ENTRY       EC 1.1.1.1                  Enzyme
NAME        alcohol dehydrogenase;
            aldehyde reductase;
            ADH;
            alcohol dehydrogenase (NAD);
            aliphatic alcohol dehydrogenase;
            ethanol dehydrogenase;
            NAD-dependent alcohol dehydrogenase;
            NAD-specific aromatic alcohol dehydrogenase;
            NADH-alcohol dehydrogenase;
            NADH-aldehyde dehydrogenase;
            primary alcohol dehydrogenase;
            yeast alcohol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     alcohol:NAD+ oxidoreductase
REACTION    an alcohol + NAD+ = an aldehyde or ketone + NADH + H+ [RN:R07326
            R07327]
ALL_REAC    R07326 > R00623 R00754 R02124 R04805 R04880 R05233 R05234 R06917
            R06927 R08281 R08306 R08557 R08558;
            R07327 > R00624 R08310;
            (other) R07105
SUBSTRATE   alcohol [CPD:C00069];
            NAD+ [CPD:C00003]
PRODUCT     aldehyde [CPD:C00071];
            ketone [CPD:C01450];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COFACTOR    Zinc [CPD:C00038]
COMMENT     A zinc protein. Acts on primary or secondary alcohols or
            hemi-acetals; the animal, but not the yeast, enzyme acts also on
            cyclic secondary alcohols.
REFERENCE   1
  AUTHORS   Branden, G.-I., Jornvall, H., Eklund, H. and Furugren, B.
  TITLE     Alcohol dehydrogenase.
  JOURNAL   In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 11, Academic
            Press, New York, 1975, p. 103-190.
REFERENCE   2  [PMID:320001]
  AUTHORS   Jornvall H.
  TITLE     Differences between alcohol dehydrogenases. Structural properties
            and evolutionary aspects.
  JOURNAL   Eur. J. Biochem. 72 (1977) 443-52.
  ORGANISM  Homo sapiens [GN:hsa], Rattus norvegicus [GN:rno], Equus caballus
            [GN:ecb], Drosophila melanogaster [GN:dme], Bacillus
            stearotherrnophilus
REFERENCE   3
  AUTHORS   Negelein, E. and Wulff, H.-J.
  TITLE     Diphosphopyridinproteid ackohol, acetaldehyd.
  JOURNAL   Biochem. Z. 293 (1937) 351-389.
REFERENCE   4
  AUTHORS   Sund, H. and Theorell, H.
  TITLE     Alcohol dehydrogenase.
  JOURNAL   In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
            ed., vol. 7, Academic Press, New York, 1963, p. 25-83.
REFERENCE   5  [PMID:13605979]
  AUTHORS   THEORELL H.
  TITLE     Kinetics and equilibria in the liver alcohol dehydrogenase system.
  JOURNAL   Adv. Enzymol. Relat. Subj. Biochem. 20 (1958) 31-49.
PATHWAY     ec00010  Glycolysis / Gluconeogenesis
            ec00071  Fatty acid metabolism
            ec00260  Glycine, serine and threonine metabolism
            ec00350  Tyrosine metabolism
            ec00625  Chloroalkane and chloroalkene degradation
            ec00626  Naphthalene degradation
            ec00830  Retinol metabolism
            ec00980  Metabolism of xenobiotics by cytochrome P450
            ec00982  Drug metabolism - cytochrome P450
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00001  alcohol dehydrogenase
            K00121  S-(hydroxymethyl)glutathione dehydrogenase / alcohol
                    dehydrogenase
            K04072  acetaldehyde dehydrogenase / alcohol dehydrogenase
            K11440  choline dehydrogenase
            K13951  alcohol dehydrogenase 1/7
            K13952  alcohol dehydrogenase 6
            K13953  alcohol dehydrogenase, propanol-preferring
            K13954  alcohol dehydrogenase
            K13980  alcohol dehydrogenase 4
GENES       HSA: 124(ADH1A) 125(ADH1B) 126(ADH1C) 127(ADH4) 128(ADH5) 130(ADH6)
                 131(ADH7)
            PTR: 461394(ADH4) 461395(ADH6) 461396(ADH1B) 471257(ADH7)
                 743928(ADH5) 744064(ADH1A) 744176(ADH1C) 744568
            PON: 100172370(ADH1A) 100450815(ADH5) 100451184(ADH4)
                 100451932(ADH1C) 100454155(ADH7)
            MCC: 697703(ADH5) 707258(ADH5) 707367(ADH4) 707585(ADH6)
                 707682(ADH1A) 707908(ADH1B) 708520(ADH7) 711061(ADH1C)
            MMU: 11522(Adh1) 11529(Adh7) 11532(Adh5) 26876(Adh4)
            RNO: 100145871(Adh5) 171178(Adh7) 24172(Adh1) 29646(Adh4)
                 310903(Adh6)
            CFA: 474946(ADH5) 478487(ADH4) 478489(ADH1C) 609781
            AML: 100466093 100466338(ADH4) 100479522
            BTA: 505515(ADH5) 509744(ADH1C) 510551(ADH6) 520508(ADH4)
            SSC: 100513366(ADH4) 100513555
            ECB: 100034175 100034242
            MDO: 100015779 100015820 100015858
            OAA: 100088518
            GGA: 395979(ADH1B) 422705(ADH5)
            TGU: 100190137 100219694 100222320 100222567
            XLA: 398993(adh1c) 432021 444547 445841(adh5) 446738(adh7)
            XTR: 100488250 496861(adh1) 496906(adh6) 496916(adh1b) 497007(adh5)
                 594969(adh1c)
            DRE: 116517(adh5)
            BFO: BRAFLDRAFT_82305 BRAFLDRAFT_82306 BRAFLDRAFT_82309
            CIN: 100187292 445671(adh3)
            SPU: 579220 756103
            DME: Dmel_CG3481(Adh) Dmel_CG6598(Fdh)
            DPO: Dpse_GA17214(Dpse_Adh) Dpse_GA19711
            DAN: Dana_GF14888(Dana_Adh) Dana_GF16175
            DER: Dere_GG17256 Dere_GG25120(Dere_Adh)
            DPE: Dper_GL12061 Dper_GL25993(Dper_Adh)
            DSE: Dsec_GM15656(Dsec_Adh) Dsec_GM26140
            DSI: Dsim_GD20694 Dsim_GD23968(Dsim_Adh)
            DWI: Dwil_GK13286 Dwil_GK18290(Dwil_Adh)
            DYA: Dyak_GE19037(Dyak_Adh) Dyak_GE24658
            DGR: Dgri_GH13025(Dgri_Adh) Dgri_GH18738
            DMO: Dmoj_GI17643(Dmoj_Adh2) Dmoj_GI24655
            DVI: Dvir_GJ18208(Dvir_Adh1) Dvir_GJ24029
            AGA: AgaP_AGAP010499
            AAG: AaeL_AAEL006458
            CQU: CpipJ_CPIJ008783
            AME: 409773(Fdh)
            NVI: 100118368(NV16308)
            TCA: 654905(Fdh)
            API: 100164837
            PHU: Phum_PHUM451780
            ISC: IscW_ISCW022174
            CEL: D2063.1 H24K24.3 K12G11.3(sodh-1) K12G11.4(sodh-2)
            CBR: CBG17892 CBG23238 CBG23239(Cbr-sodh-1)
            BMY: Bm1_52445
            SMM: Smp_044440
            HMG: 100199970
            TAD: TRIADDRAFT_29716 TRIADDRAFT_55892
            ATH: AT1G22430 AT1G22440 AT1G32780 AT1G64710 AT1G77120(ADH1)
                 AT4G22110 AT5G24760 AT5G42250 AT5G43940(HOT5)
            POP: POPTR_1075155 POPTR_176894 POPTR_232962 POPTR_294427
                 POPTR_558388 POPTR_558390 POPTR_562436 POPTR_573385(GSH-FDH2)
                 POPTR_645542(GSH-FDH1) POPTR_718546 POPTR_782655 POPTR_815974
                 POPTR_816232 POPTR_827290 POPTR_832230
            RCU: RCOM_0138590 RCOM_0138830 RCOM_0236080 RCOM_0996200
                 RCOM_1222910 RCOM_1313890 RCOM_1600190
            VVI: 100232853(ADH1) 100232854(ADH2) 100233102(ADH3) 100245520
                 100250633 100254635 100255814 100256495 100258412 100259248
                 100264420 100267821
            OSA: 4330090 4331130 4331893 4331894 4343942 4348152 4350053 4350054
                 4350055
            SBI: SORBI_01g025570 SORBI_01g025580 SORBI_01g044580 SORBI_01g044590
                 SORBI_04g027090 SORBI_04g037050 SORBI_05g009350 SORBI_05g009360
            ZMA: 100193894 100272357 100272578(cl33662_1) 100273217(pco147721a)
                 100274539 542363(adh1) 542364(adh2) 542459(fdh1)
            PPP: PHYPADRAFT_101898 PHYPADRAFT_105455 PHYPADRAFT_119828
                 PHYPADRAFT_137950 PHYPADRAFT_183406
            CRE: CHLREDRAFT_129874(FDH1)
            VCN: VOLCADRAFT_82410
            OLU: OSTLU_27414(ADHX)
            OTA: Ot15g01360
            CME: CMS125C
            SCE: YBR145W(ADH5) YDL168W(SFA1) YGL256W(ADH4) YMR083W(ADH3)
                 YMR303C(ADH2) YOL086C(ADH1)
            AGO: AGOS_AAR084W AGOS_ABL033C AGOS_ACL148C AGOS_AER032W
            KLA: KLLA0B00451g KLLA0B09064g KLLA0C19382g KLLA0D12342g
                 KLLA0F13530g KLLA0F18260g KLLA0F21010g
            LTH: KLTH0A00418g KLTH0D05588g KLTH0E05588g KLTH0G15686g
                 KLTH0H01254g
            PPA: PAS_chr2-1_0472 PAS_chr3_1028
            VPO: Kpol_1036p19 Kpol_431p8 Kpol_530p31
            ZRO: ZYRO0B05940g ZYRO0C12562g ZYRO0F11704g ZYRO0G03388g
                 ZYRO0G03410g
            CGR: CAGL0I07843g CAGL0J01441g CAGL0L01111g
            DHA: DEHA2C00880g DEHA2F03938g DEHA2G05808g DEHA2G21032g
            PIC: PICST_27980(ADH2) PICST_29252(FDH1) PICST_59150(SAD1)
                 PICST_67803(SAD2) PICST_68558(ADH1)
            PGU: PGUG_01281 PGUG_01479 PGUG_02240 PGUG_02909
            LEL: LELG_00122 LELG_00373 LELG_01971 LELG_04006 LELG_05277
            CAL: CaO19.10139(SAD1) CaO19.11480(ADH1) CaO19.11980(SAD2)
                 CaO19.12579(ADH2) CaO19.3997(ADH1) CaO19.5113(ADH2)
                 CaO19.7600(SFA1)
            CTP: CTRG_00882 CTRG_01595 CTRG_05197 CTRG_05482 CTRG_05836
                 CTRG_06113
            CDU: CD36_07850 CD36_19080 CD36_27000 CD36_35225(FDH1) CD36_54650
            YLI: YALI0A15147g YALI0A16379g YALI0D25630g YALI0E17787g
                 YALI0F09603g
            CLU: CLUG_00171 CLUG_01827 CLUG_05099 CLUG_05794
            NCR: NCU01754 NCU02476 NCU06652
            PAN: PODANSg3584 PODANSg6586 PODANSg8007
            MGR: MGG_03880(MG03880.4) MGG_06011(MG06011.4)
            FGR: FG02291.1 FG10200.1 FG10855.1 FG11557.1
            SSL: SS1G_10135 SS1G_13409
            BFU: BC1G_06394 BC1G_11838
            ANI: AN0024.2 AN2286.2 AN7632.2 AN8979.2
            AFM: AFUA_2G01040 AFUA_5G06240 AFUA_7G01010
            NFI: NFIA_033340 NFIA_036880 NFIA_045020 NFIA_113720
            AOR: AO090009000634 AO090010000616 AO090308000002 AO090701000373
                 AO090701000508
            ANG: An01g12170 An10g00510 An13g03330 An17g01530(adhA)
            AFV: AFLA_024290 AFLA_048690 AFLA_058310 AFLA_059790 AFLA_072340
                 AFLA_120970 AFLA_125860 AFLA_138950
            ACT: ACLA_009560 ACLA_066630 ACLA_094350
            PCS: Pc12g07100 Pc12g13440 Pc16g06960 Pc21g19580 Pc21g22820
                 Pc22g25070
            CIM: CIMG_00198 CIMG_03030 CIMG_06053
            CPW: CPC735_000030 CPC735_026240 CPC735_059600
            URE: UREG_00297 UREG_02928 UREG_04323
            PNO: SNOG_00802 SNOG_08675 SNOG_10173 SNOG_10471
            TML: GSTUM_00005441001 GSTUM_00006862001
            SPO: SPAC5H10.06c(adh4) SPBC1539.07c SPCC13B11.01(adh1)
                 SPCC13B11.04c
            CNE: CNE00710 CNG00600 CNM01690
            CNB: CNBE0650 CNBG4180 CNBM1570
            PPL: POSPLDRAFT_88101
            LBC: LACBIDRAFT_179500 LACBIDRAFT_292173
            MPR: MPER_03004 MPER_05513 MPER_06392
            CCI: CC1G_00131 CC1G_07718
            SCM: SCHCODRAFT_110065 SCHCODRAFT_54429 SCHCODRAFT_62676
                 SCHCODRAFT_72421 SCHCODRAFT_85910
            UMA: UM01984.1 UM02790.1 UM06244.1
            MGL: MGL_0044
            MBR: MONBRDRAFT_20739 MONBRDRAFT_32407
            NGR: NAEGRDRAFT_55836 NAEGRDRAFT_56035
            DDI: DDB_G0274085 DDB_G0281865(adh5)
            EHI: EHI_150490(124.t00001)
            EDI: EDI_342050
            CPV: cgd8_1720
            CHO: Chro.80199
            TGO: TGME49_111780
            TCR: 506357.50 511277.60
            PTI: PHATRDRAFT_12757(ADH_2)
            TPS: THAPSDRAFT_1394(ADH1) THAPSDRAFT_26523
            PIF: PITG_05373 PITG_10292
            ECO: b0356(frmA) b1241(adhE) b1478(adhP) b3589(yiaY)
            ECJ: JW0347(frmA) JW1228(adhE) JW1474(adhP) JW5648(yiaY)
            ECD: ECDH10B_0311(frmA) ECDH10B_1302(adhE) ECDH10B_1609(adhP)
                 ECDH10B_3770(yiaY)
            EBW: BWG_0245(frmA) BWG_1066(adhE) BWG_1299(adhP) BWG_3279(yiaY)
            ECE: Z0456(adhC) Z2016(adhE) Z2232(adhP) Z5010(yiaY)
            ECS: ECs0411 ECs1741 ECs2082(adhA) ECs4466
            ECF: ECH74115_0431(adhC) ECH74115_1725(adhE) ECH74115_2090
                 ECH74115_4960(adhB)
            ETW: ECSP_0420(frmA) ECSP_1631(adhE) ECSP_1962(adhP) ECSP_4582(yiaY)
            EOJ: ECO26_0392(frmA) ECO26_1752(adhE) ECO26_2076(adhP)
                 ECO26_5012(yiaY)
            EOI: ECO111_0392(frmA) ECO111_1568(adhE) ECO111_1868(adhP)
                 ECO111_4409(yiaY)
            EOH: ECO103_0338(frmA) ECO103_1341(adhE) ECO103_1607(adhP)
                 ECO103_4645(yiaY)
            ECG: E2348C_0303(frmA) E2348C_1367(adhE) E2348C_1612(adhP)
                 E2348C_3839(yiaY)
            EOK: G2583_0469(frmA) G2583_1513(adhE) G2583_1841(adhP)
                 G2583_4325(yiaY)
            ECC: c0465(adhC) c1705(adhE) c1911(adhP) c4410(yiaY)
            ECP: ECP_0421 ECP_1287 ECP_1480(adhA) ECP_3691
            ECI: UTI89_C0376(adhC) UTI89_C1438(adhE) UTI89_C1696(adhP)
                 UTI89_C4131(yiaY)
            ECV: APECO1_1645(adhC) APECO1_2864(yiaY) APECO1_355(adhE)
                 APECO1_614(adhP)
            ECX: EcHS_A0421(adhC) EcHS_A1350(adhE) EcHS_A1563 EcHS_A3794(adhB)
            ECW: EcE24377A_0381 EcE24377A_1389(adhE) EcE24377A_1660
                 EcE24377A_4087(adhB)
            ECM: EcSMS35_0387(adhC) EcSMS35_1696 EcSMS35_1901(adhE)
                 EcSMS35_3917(adhB)
            ECY: ECSE_0381 ECSE_1289 ECSE_1567 ECSE_3866
            ECR: ECIAI1_0357(frmA) ECIAI1_1259(adhE) ECIAI1_1482(adhP)
                 ECIAI1_3757(yiaY)
            ECQ: ECED1_0384(frmA) ECED1_1392(adhE) ECED1_1631(adhP)
                 ECED1_4275(yiaY)
            ECK: EC55989_0365(frmA) EC55989_1337(adhE) EC55989_1610(adhP)
                 EC55989_4047(yiaY)
            ECT: ECIAI39_0322(frmA) ECIAI39_1575(adhE) ECIAI39_1742(adhP)
                 ECIAI39_4107(yiaY)
            EUM: ECUMN_0399(frmA) ECUMN_1538(adhE) ECUMN_1733(adhP)
                 ECUMN_4104(yiaY)
            ECZ: ECS88_0356(frmA) ECS88_1308(adhE) ECS88_1572(adhP)
                 ECS88_4006(yiaY)
            ECL: EcolC_0124 EcolC_2179 EcolC_2387 EcolC_3269
            EBR: ECB_00310(frmA) ECB_01215(adhE) ECB_01436(adhP) ECB_03444(yiaY)
            EBD: ECBD_0141 ECBD_2161 ECBD_2383 ECBD_3301
            EFE: EFER_1495(adhP) EFER_1582(frmA) EFER_1714(adhE) EFER_3583(yiaY)
            STY: STY1302(adh) STY1493(adhP) STY3830
            STT: t1482(adhP) t1660(adh) t3575
            STM: STM1567(adhP) STM1627 STM1749(adhE) STM4044
            SPT: SPA1129(adh) SPA1301(adhP) SPA3887
            SEK: SSPA1048 SSPA1209 SSPA3615
            SPQ: SPAB_01493 SPAB_01652 SPAB_01731 SPAB_02687
            SEI: SPC_1980(adh) SPC_2108 SPC_2171(adhP) SPC_4148
            SEC: SC1568(adhP) SC1622(adh3) SC1744(adhE) SC3934(adh2)
            SEH: SeHA_C1744 SeHA_C1805 SeHA_C1939(adhE)
            SEE: SNSL254_A1681 SNSL254_A1741 SNSL254_A1876(adhE)
            SEW: SeSA_A1683 SeSA_A1746 SeSA_A1882(adhE) SeSA_A3881
            SEA: SeAg_B1396(adhE) SeAg_B1530 SeAg_B1598
            SED: SeD_A1579(adhE) SeD_A1715 SeD_A1776
            SEG: SG1367(adhE) SG1492 SG1560(adhP)
            SET: SEN1287(adhE) SEN1425 SEN1488(adhP) SEN3835
            SES: SARI_01204 SARI_01356 SARI_01402 SARI_03603 SARI_03967
            YPE: YPO1502 YPO2180(adhE)
            YPK: y2023(adhE) y2667(adhC)
            YPA: YPA_0797 YPA_1537
            YPN: YPN_1646 YPN_2477
            YPM: YP_1392(adhC) YP_1976(adhE)
            YPP: YPDSF_0956 YPDSF_1475
            YPG: YpAngola_A2165(adhE) YpAngola_A3011
            YPZ: YPZ3_1369(adhC) YPZ3_1666(adhE)
            YPS: YPTB1517 YPTB2103(adhE)
            YPI: YpsIP31758_1963(adhE) YpsIP31758_2473
            YPY: YPK_2072 YPK_2571
            YPB: YPTS_1627 YPTS_2171
            YEN: YE2238(adhE) YE2821
            SFL: SF1240(adhE) SF1747(adhP) SF3627(yiaY)
            SFX: S1326(adhE) S1880(adhP) S4141(yiaY)
            SFV: SFV_1253(adhE) SFV_3944(yiaY)
            SSN: SSON_0335(adhC) SSON_1939(adhE)
            SBO: SBO_1828(adhE) SBO_3589(yiaY)
            SBC: SbBS512_E0271(adhC) SbBS512_E1406(adhE) SbBS512_E4004(adhB)
            SDY: SDY_1295(adhE) SDY_1608(adhP)
            ECA: ECA2326(adhE) ECA2714(adhC)
            PCT: PC1_1667 PC1_1983 PC1_2984
            PWA: Pecwa_1288 Pecwa_1938 Pecwa_2284
            ETA: ETA_12850(adhC) ETA_15810(adhE) ETA_24370(adhP)
            EPY: EpC_13460(adhC) EpC_25500(adhP)
            EAM: EAMY_1054(adhP) EAMY_1942(adhE3) EAMY_2294(adhC1)
            EAY: EAM_1064(adhP) EAM_1900(adhE) EAM_2212(adhC)
            EBI: EbC_23190 EbC_24010 EbC_29900(adhC)
            PLU: plu1563 plu2496(adhE) plu4332(adhC)
            PAY: PAU_02030(adhE) PAU_02881(yiaY) PAU_03905(adhC)
            SGL: SG1372
            ENT: Ent638_0142 Ent638_1960 Ent638_2304 Ent638_4074
            ENC: ECL_01635 ECL_01908 ECL_02059
            ESC: Entcl_2072 Entcl_2245
            ESA: ESA_01539 ESA_01682 ESA_01709 ESA_03873
            CTU: Ctu_01340(yiaY) Ctu_22450(frmA) Ctu_22760(adhA) Ctu_23840(adhE)
            KPN: KPN_01853(adhP) KPN_01952 KPN_02199(adhE) KPN_04206
                 KPN_pKPN5p08231 KPN_pKPN5p08257
            KPE: KPK_2109(adhE) KPK_2397(adhC) KPK_2503 KPK_5475
            KPU: KP1_0065 KP1_2916(adhP) KP1_3020 KP1_3311(adhE)
            KVA: Kvar_1983 Kvar_2351 Kvar_2451
            CKO: CKO_01318 CKO_01455 CKO_03104 CKO_05045
            CRO: ROD_08021(adh) ROD_16171(adhC) ROD_17681(adhE) ROD_42281
            SPE: Spro_1557 Spro_2403 Spro_2704 Spro_3658
            PMR: PMI0450(adhC) PMI0657 PMI1486(adhE)
            EIC: NT01EI_0882 NT01EI_1665
            ETR: ETAE_0770 ETAE_1508(adhE)
            DDA: Dd703_1776 Dd703_1955 Dd703_2311
            DDC: Dd586_1822 Dd586_2144 Dd586_2347
            DDD: Dda3937_00069(adhC) Dda3937_03796(yiaY) Dda3937_04056(adhE)
            DZE: Dd1591_1857 Dd1591_2197 Dd1591_2411
            XBO: XBJ1_0925(yiaY) XBJ1_2430(adhE) XBJ1_3896(adhC)
            XNE: XNC1_1507(yiaY) XNC1_2054(adhC) XNC1_2481(adhE)
            PAM: PANA_0985(adhP) PANA_2089(adhE) PANA_2547(adhC) PANA_3008(yphC)
            PVA: Pvag_1532(adhE) Pvag_1623(adhP) Pvag_2032(adhc1)
            PAO: Pat9b_0932 Pat9b_2178 Pat9b_2644
            HIN: HI0185(adhC)
            HIP: CGSHiEE_02335
            HIQ: CGSHiGG_03525
            PMU: PM1453(adh2)
            MSU: MS1386(adhC) MS1802(eutG) MS2190(eutG)
            APL: APL_1011(adh2) APL_1208(adhC) APL_1959(adhI)
            APJ: APJL_1029(adh2) APJL_1221(adh1) APJL_2006(adh3)
            APA: APP7_1068(adhE) APP7_1259 APP7_2047
            ASU: Asuc_0067 Asuc_0403 Asuc_0591
            AAP: NT05HA_1312
            AAT: D11S_0481 D11S_1811
            XCC: XCC3389 XCC3475(adhC)
            XCB: XC_0686 XC_0775
            XCA: xccb100_0720(adh) xccb100_0810
            XCV: XCV0713 XCV0788 XCV2333
            XAC: XAC0652(adhC) XAC0734 XAC2826
            XOO: XOO1535 XOO3867
            XOM: XOO_1325 XOO_1423 XOO_3647 XOO_4231
            XOP: PXO_04416 PXO_04785
            XAL: XALc_0862 XALc_1049
            SML: Smlt3978(adhC)
            SMT: Smal_0028 Smal_3387
            PSU: Psesu_2747
            VCH: VC2033
            VCO: VC0395_A1619(adhE)
            VCM: VCM66_1957(adhE)
            VCJ: VCD_002334
            VVU: VV1_0344 VV1_3111 VV2_0019
            VVY: VV0841 VV1175 VV2175 VVA0527
            VVM: VVM_01008 VVM_03625 VVM_03960
            VPA: VP2121 VPA0071 VPA0566
            VHA: VIBHAR_03018 VIBHAR_05412 VIBHAR_06925
            VSP: VS_0958 VS_II0445 VS_II1327
            VEX: VEA_000929 VEA_001472 VEA_002931
            VFI: VF_0645(frmA) VF_0648 VF_0918(adhE) VF_1188(yiaY)
            VFM: VFMJ11_0659 VFMJ11_0663 VFMJ11_0957 VFMJ11_1266
            VSA: VSAL_I0746(adhC) VSAL_I1788(adhB) VSAL_I1855(adhE)
            PPR: PBPRA0784 PBPRA1103 PBPRA1480 PBPRA2519
            PAE: PA3629(adhC) PA5427(adhA)
            PAU: PA14_17400(adhC) PA14_71630(adhA)
            PAP: PSPA7_1510 PSPA7_6215(adhA)
            PAG: PLES_14061(adhC) PLES_30921 PLES_58221(adhA)
            PPU: PP_1616 PP_3839(adhA)
            PPF: Pput_1932(adhA) Pput_4161
            PPG: PputGB1_1170 PputGB1_3554
            PPW: PputW619_2066 PputW619_4059
            PST: PSPTO_1558(adhC) PSPTO_4285(adhB)
            PSB: Psyr_1367 Psyr_2956 Psyr_3987
            PSP: PSPPH_3816(adhC) PSPPH_3994(adhB)
            PFL: PFL_1200 PFL_1399(adhB)
            PFO: Pfl01_1125 Pfl01_1311
            PFS: PFLU1295(adhC) PFLU1412 PFLU4115
            PEN: PSEEN2613(adhC-1) PSEEN2959(adhB) PSEEN4196(adhC-2)
            PMY: Pmen_0120 Pmen_0381 Pmen_2529 Pmen_3028
            PSA: PST_0312 PST_1563(adhC) PST_2239 PST_4153(adhA)
            CJA: CJA_3340(adhC)
            AVN: Avin_00880 Avin_07960 Avin_07980 Avin_38750
            PAR: Psyc_0011 Psyc_1042 Psyc_1671(adhC)
            PCR: Pcryo_0018 Pcryo_1428 Pcryo_1939
            PRW: PsycPRwf_1032 PsycPRwf_1071
            ACI: ACIAD1879(adhC) ACIAD1950 ACIAD2015 ACIAD2929 ACIAD3339(adhA)
            ACD: AOLE_06670 AOLE_09790
            ACB: A1S_2053 A1S_2098 A1S_2702
            ABM: ABSDF0756 ABSDF1641 ABSDF2205
            ABY: ABAYE0763 ABAYE1463 ABAYE1522 ABAYE1861(frmA) p2ABAYE0004
                 p3ABAYE0024(adhC)
            ABC: ACICU_01808 ACICU_02295
            ABN: AB57_2002 AB57_2430
            ABB: ABBFA_001368 ABBFA_001721
            MCT: MCR_0444(adhC)
            SON: SO_1490(adhB) SO_2054(adhC) SO_2136(adhE) SO_A0161 SO_A0164
            SDN: Sden_2000 Sden_2578 Sden_3767
            SFR: Sfri_1898 Sfri_2798 Sfri_3427 Sfri_4059
            SAZ: Sama_0004 Sama_1693 Sama_2455
            SBL: Sbal_1321 Sbal_1922 Sbal_2419
            SBM: Shew185_1312 Shew185_1948 Shew185_2408
            SBN: Sbal195_1348 Sbal195_1955 Sbal195_2526
            SBP: Sbal223_1940 Sbal223_2371 Sbal223_3038
            SLO: Shew_1166 Shew_1540 Shew_1910
            SPC: Sputcn32_1244 Sputcn32_1811 Sputcn32_2174
            SSE: Ssed_1258 Ssed_2349 Ssed_2530 Ssed_4227
            SPL: Spea_0269 Spea_1152 Spea_2044 Spea_3021
            SHE: Shewmr4_1683 Shewmr4_1786 Shewmr4_2762
            SHM: Shewmr7_1758 Shewmr7_2191 Shewmr7_2840
            SHN: Shewana3_1788 Shewana3_1837 Shewana3_2938
            SHW: Sputw3181_1835 Sputw3181_2214 Sputw3181_2860
            SHL: Shal_1196 Shal_2250 Shal_3111 Shal_4033
            SWD: Swoo_0375 Swoo_1359 Swoo_2241
            SWP: swp_1311 swp_2093 swp_2623
            SVO: SVI_1071(adhB) SVI_2024(adhE) SVI_3328(adhC)
            ILO: IL0796 IL1773(adhC)
            CPS: CPS_0817 CPS_1431 CPS_3853
            PHA: PSHAa1386(adhC) PSHAa1488(yhdH) PSHAa2213(adhC) PSHAb0511(adhP)
            PAT: Patl_0425 Patl_1438 Patl_1481 Patl_1829
            PSM: PSM_A1422(adhC) PSM_B0592(adhP)
            SDE: Sde_0052
            MAQ: Maqu_0321 Maqu_1048 Maqu_1713 Maqu_2251
            AMC: MADE_03331
            PIN: Ping_1955 Ping_3315 Ping_3530
            TTU: TERTU_0454
            FBL: Fbal_1490 Fbal_2057 Fbal_2905
            LPN: lpg2492
            LPF: lpl2413
            LPP: lpp2558
            LPC: LPC_1984(adhT)
            LPA: lpa_03633(adhP)
            LLO: LLO_1570 LLO_2480(frmA)
            MCA: MCA0775
            FTU: FTT_0883
            FTM: FTM_0472
            FTN: FTN_0409(adhC)
            FPH: Fphi_0427
            TCX: Tcr_0211
            NOC: Noc_1394
            NWA: Nwat_1687
            AEH: Mlg_1412
            HHA: Hhal_0140
            HCH: HCH_01446(adhC) HCH_05054
            CSA: Csal_0985 Csal_1091 Csal_1426 Csal_2912
            HEL: HELO_2818(adh2) HELO_3466(adhC)
            ABO: ABO_0061 ABO_0117(adhC) ABO_0817 ABO_1231(adhA) ABO_1352(adhB)
                 ABO_2483
            KKO: Kkor_2048
            MMW: Mmwyl1_0234 Mmwyl1_0237 Mmwyl1_1967 Mmwyl1_2290 Mmwyl1_3680
            AHA: AHA_0214 AHA_1331 AHA_1463 AHA_2616
            ASA: ASA_1695(adhE) ASA_2860 ASA_2902 ASA_4180(adhC)
            TAU: Tola_2176 Tola_2876
            AFE: Lferr_0845 Lferr_1744
            AFR: AFE_0697 AFE_2088
            GPB: HDN1F_08500(adhC) HDN1F_20690
            NMA: NMA0725(adhA) NMA1518
            NME: NMB0546(adhP) NMB1304 NMB1395
            NMC: NMC0486(adhA) NMC1241(adhC)
            NMN: NMCC_0488(adhP) NMCC_1217(adhC)
            NMI: NMO_0428(adhA) NMO_1145(adhC)
            NGO: NGO0711 NGO1442(adhA)
            NGK: NGK_1316 NGK_1317
            NLA: NLA_11390(adhC) NLA_16930(adhA)
            CVI: CV_0740(adhC) CV_0808 CV_1137(adhE) CV_2728
            LHK: LHK_02379(fdhG)
            RSO: RS00889(RSp0430) RSc0181 RSc0605(adhC2) RSc1505 RSc3130(adhA)
                 RSp0069(adhC1)
            RSC: RCFBP_10307(adhA) RCFBP_11485 RCFBP_20867(adhI)
            RSL: RPSI07_0355(adhA) RPSI07_1540 RPSI07_2746(adhI)
            RPI: Rpic_0535 Rpic_4437
            RPF: Rpic12D_0522 Rpic12D_4570
            REU: Reut_B3677 Reut_B4000 Reut_B4710 Reut_B4833 Reut_B5201
                 Reut_C6082 Reut_C6089 Reut_C6321
            REH: H16_A0861 H16_A3330 H16_B0517 H16_B1195(adhC) H16_B1433(adhP)
                 H16_B1699 H16_B1745 H16_B2470
            RME: Rmet_0545 Rmet_1093 Rmet_4784(frmA) Rmet_4943 Rmet_5102
                 Rmet_5545
            CTI: RALTA_B1113(adhC) RALTA_B2189
            BMA: BMA0324 BMAA0132 BMAA0163
            BMV: BMASAVP1_1300 BMASAVP1_1333 BMASAVP1_A0622
            BML: BMA10229_A2456
            BMN: BMA10247_0070 BMA10247_A0157 BMA10247_A0189
            BPS: BPSL0820(flhA) BPSS1918 BPSS1944(adhA)
            BPM: BURPS1710b_1025(flhA) BURPS1710b_2237(eutG) BURPS1710b_A1018
                 BURPS1710b_A1046(adhA)
            BPL: BURPS1106A_0866 BURPS1106A_2097 BURPS1106A_A2605
                 BURPS1106A_A2642
            BPD: BURPS668_0862 BURPS668_2042 BURPS668_A2748 BURPS668_A2784
            BPR: GBP346_A0790 GBP346_A2168
            BTE: BTH_I0686 BTH_I2335 BTH_II0428 BTH_II0459
            BVI: Bcep1808_1701 Bcep1808_4603 Bcep1808_4991 Bcep1808_6339
                 Bcep1808_6458 Bcep1808_6708
            BUR: Bcep18194_A5935 Bcep18194_B2077 Bcep18194_B2551 Bcep18194_C6773
            BCN: Bcen_1994 Bcen_3928 Bcen_4360 Bcen_4742
            BCH: Bcen2424_2604 Bcen2424_3424 Bcen2424_4006 Bcen2424_4438
            BCM: Bcenmc03_2628 Bcenmc03_3517 Bcenmc03_4093 Bcenmc03_5867
            BCJ: BCAL2817(flhA) BCAM0286 BCAM1570(adhA) BCAS0075
            BAM: Bamb_3412 Bamb_3811 Bamb_3870 Bamb_6311
            BAC: BamMC406_1680 BamMC406_3919 BamMC406_4279 BamMC406_4330
                 BamMC406_6016
            BMU: Bmul_0693 Bmul_1502 Bmul_4573 Bmul_5179 Bmul_5633 Bmul_5905
            BMJ: BMULJ_01740(adh) BMULJ_02567(adhC) BMULJ_03339(adh)
                 BMULJ_03937(adh) BMULJ_05620(adh) BMULJ_05877(adhC)
            BXE: Bxe_A0713(flhA) Bxe_A1730 Bxe_A1844 Bxe_A1872 Bxe_B1066
                 Bxe_B2357 Bxe_B2518 Bxe_C0527 Bxe_C1266
            BPH: Bphy_0483 Bphy_5774 Bphy_5870
            BPY: Bphyt_0108 Bphyt_3253 Bphyt_5114 Bphyt_5668 Bphyt_6316
            BGL: bglu_1g29580 bglu_2g07050 bglu_2g14520 bglu_2g20380
                 bglu_2g20480
            BGE: BC1002_1594 BC1002_4131 BC1002_5918 BC1002_6141
            BRH: RBRH_01957
            BPE: BP0777 BP2601 BP3751(adhI)
            BPA: BPP2723 BPP4251(adhI)
            BBR: BB0342 BB2775 BB4838(adhI)
            BPT: Bpet0155 Bpet3517(attL)
            BAV: BAV0490 BAV3289(adhC)
            AXY: AXYL_00280(adhC) AXYL_03298 AXYL_05019(adh2)
            RFR: Rfer_0121 Rfer_2865
            POL: Bpro_1201 Bpro_3129 Bpro_5563
            PNA: Pnap_1230 Pnap_1291 Pnap_2299
            AAV: Aave_2195 Aave_3231
            AJS: Ajs_1375 Ajs_1889 Ajs_2098 Ajs_2800
            DIA: Dtpsy_1693 Dtpsy_2290
            VEI: Veis_3295 Veis_4025 Veis_4413
            DAC: Daci_0183 Daci_2414 Daci_2868
            VAP: Vapar_1703
            VPE: Varpa_1874
            CTT: CtCNB1_3405 CtCNB1_4266
            ADN: Alide_2351 Alide_2853 Alide_3464 Alide_3949
            MPT: Mpe_A0936
            HAR: HEAR0089 HEAR1070 HEAR2039 HEAR2367(adh)
            MMS: mma_0221(adhC) mma_1172(adhI)
            HSE: Hsero_0964(adhA) Hsero_2713(adhC) Hsero_2795(adhC2)
            LCH: Lcho_3255
            TIN: Tint_1602
            NEU: NE0620 NE0907(adhC1)
            NET: Neut_1385
            NMU: Nmul_A1937 Nmul_A2272
            EBA: ebA4623(adhB) ebA5713(fdhG) p2A334
            AZO: azo0111(adhA) azo1971 azo2700 azo3181 azo3317(yhdH)
                 azo3623(adhC)
            DAR: Daro_1348
            TMZ: Tmz1t_0608 Tmz1t_2296
            TBD: Tbd_1767
            APP: CAP2UW1_1635 CAP2UW1_1902
            GSU: GSU0573
            GME: Gmet_1046
            GUR: Gura_2420 Gura_3574
            GLO: Glov_3003
            GBM: Gbem_1353
            GEO: Geob_0268 Geob_2516
            GEM: GM21_2932
            PCA: Pcar_0251 Pcar_0255 Pcar_1246 Pcar_1594 Pcar_2506 Pcar_2758
                 Pcar_2847
            PPD: Ppro_0887 Ppro_1924
            DVU: DVU2396 DVU2405 DVU2885 DVU2905
            DVL: Dvul_0460 Dvul_0480 Dvul_0825 Dvul_0834
            DVM: DvMF_0321 DvMF_1315 DvMF_2322
            DDE: Dde_1164 Dde_3062 Dde_3126 Dde_3283 Dde_3523 Dde_3534
            DDS: Ddes_1943
            DMA: DMR_01890 DMR_16700
            DSA: Desal_0284 Desal_1318
            DBA: Dbac_3326
            DRT: Dret_0199
            BBA: Bd0898(adhC) Bd2813(adh)
            DPS: DP0950 DP0951 DP0952 DP0955
            DAK: DaAHT2_0946
            DPR: Despr_1637
            DOL: Dole_2290
            DAL: Dalk_4478
            DAT: HRM2_02030(adh3) HRM2_15420(adh4)
            ADE: Adeh_1418
            ACP: A2cp1_2529
            AFW: Anae109_2555 Anae109_3065 Anae109_3732 Anae109_4129
            ANK: AnaeK_2442
            MXA: MXAN_0456 MXAN_7094
            SCL: sce2769(adh2) sce4900(adh5)
            HOH: Hoch_5737
            SAT: SYN_01159
            SFU: Sfum_0829
            DBR: Deba_0709
            PUB: SAR11_0272(adhP) SAR11_0529 SAR11_1244(yhdH) SAR11_1287
            MLO: mlr0872 mlr1136 mlr1178
            MCI: Mesci_2060 Mesci_4169
            MES: Meso_1317 Meso_1868 Meso_2263 Meso_2671
            PLA: Plav_0046 Plav_2451 Plav_3009 Plav_3345
            SME: SM_b20170(fdh) SMa1296(adhA1) SMa2113(adhC2) SMc00105
                 SMc01270(adhC1) SMc03929 SMc04270
            SMD: Smed_0584 Smed_1024 Smed_2128 Smed_2747 Smed_2996 Smed_3946
            RHI: NGR_b11340 NGR_b14640(adhC2) NGR_b16300 NGR_b16470(adhC3)
                 NGR_b23560(adhC4) NGR_c03790 NGR_c07250 NGR_c12280(adhC6)
                 NGR_c20470(adhC5) NGR_c25690 NGR_c26770
            ATU: Atu0626(adhP) Atu1595 Atu1670(adhC) Atu2151(adh) Atu4289(adhC)
                 Atu5240(adhP)
            ARA: Arad_1406 Arad_2510 Arad_7565(adhA2)
            AVI: Avi_2506(adhC) Avi_5768(adhP) Avi_8187(adhP) Avi_9223(adhP)
            RET: RHE_CH00460(ypch00170) RHE_CH01189(ypch00392)
                 RHE_CH02227(adhCch) RHE_CH02474(ypch00832)
                 RHE_CH02884(ypch00995) RHE_PB00029(ypb00013) RHE_PC00105(adhA1)
                 RHE_PC00106(adhA2) RHE_PD00107(adhE) RHE_PF00203(ypf00099)
                 RHE_PF00365(ypf00190) RHE_PF00402(adhCf)
            REC: RHECIAT_CH0001280 RHECIAT_CH0002337(adhCch) RHECIAT_PB0000039
                 RHECIAT_PB0000128(adhE) RHECIAT_PC0000584(adhCc)
            RLE: RL0310 RL1325 RL1876(adh) RL2813 RL3344 pRL100135 pRL120042
                 pRL120182 pRL120524(adhI) pRL120602 pRL90027(adhA) pRL90098
            RLT: Rleg2_0831 Rleg2_1875 Rleg2_4918 Rleg2_4957
            RLG: Rleg_0950 Rleg_4830
            BME: BMEI0925 BMEI1114 BMEI1746 BMEI1819 BMEII0553 BMEII0867
            BMI: BMEA_A0137 BMEA_A0212 BMEA_A1102 BMEA_B0380
            BMF: BAB1_0128 BAB1_0204 BAB1_0871 BAB2_0506 BAB2_0821
            BMB: BruAb1_0127 BruAb1_0198 BruAb1_0864 BruAb2_0498 BruAb2_0800
            BMC: BAbS19_I01220 BAbS19_I01920
            BMS: BR0203 BR0852 BR1061 BRA0401 BRA0734
            BMT: BSUIS_A0204(adhT) BSUIS_A0890 BSUIS_A1105 BSUIS_B0404
            BOV: BOV_0195 BOV_0844 BOV_1026 BOV_A0344
            BCS: BCAN_A0133 BCAN_A0207(adhT) BCAN_A0865 BCAN_A1076 BCAN_B0404
            BMR: BMI_I1066 BMI_I133 BMI_I207 BMI_II398
            OAN: Oant_0144 Oant_0272 Oant_3883
            BJA: bll4101 bll5655 bll7898 blr2780 blr3675 blr4874 blr6070
                 blr6215(adhC)
            BRA: BRADO0250 BRADO0921(adh) BRADO2457 BRADO2866(adhA) BRADO3321
                 BRADO4151 BRADO4353 BRADO5308 BRADO5486(adhC) BRADO6611
            BBT: BBta_2803 BBta_3627 BBta_3825 BBta_4528 BBta_5308(adhA)
                 BBta_5755 BBta_5970(adhC) BBta_7131(adh)
            RPA: RPA0374 RPA1205 RPA1955 RPA2018 RPA3067 RPA3655
            RPB: RPB_0946 RPB_1148 RPB_1871 RPB_2474 RPB_3418
            RPC: RPC_0101 RPC_0105 RPC_1965 RPC_2107 RPC_2307 RPC_2974 RPC_3411
                 RPC_4481
            RPD: RPD_1250 RPD_2034 RPD_2086 RPD_2972 RPD_3495
            RPE: RPE_0587 RPE_1228 RPE_2019 RPE_3298 RPE_3692 RPE_4678
            RPT: Rpal_0378 Rpal_1398 Rpal_2166 Rpal_4176 Rpal_4444
            RPX: Rpdx1_0211 Rpdx1_1429 Rpdx1_1695 Rpdx1_3551 Rpdx1_4112
            NWI: Nwi_1739
            NHA: Nham_1916 Nham_2168 Nham_2346
            OCA: OCAR_5733 OCAR_6826 OCAR_6856
            BQU: BQ05280(adh)
            BBK: BARBAKC583_0618
            BTR: Btr_1329(adh)
            XAU: Xaut_2010 Xaut_2610
            AZC: AZC_0105 AZC_0320
            SNO: Snov_2400 Snov_3186
            MEA: Mex_1p3803
            MDI: METDI4540
            MRD: Mrad2831_2614
            MET: M446_1233 M446_6106
            MNO: Mnod_5387
            BID: Bind_0774 Bind_0909 Bind_2495
            MSL: Msil_1821 Msil_2439
            RVA: Rvan_0682 Rvan_1029
            CCR: CC_2516 CC_3029
            CCS: CCNA_02601 CCNA_03124
            CAK: Caul_0743 Caul_2341 Caul_2449 Caul_2461 Caul_3517
            CSE: Cseg_1190 Cseg_3013 Cseg_3464 Cseg_3521
            PZU: PHZ_c0845(adhI) PHZ_c2025 PHZ_c2794
            BSB: Bresu_3128 Bresu_3195
            AEX: Astex_1746 Astex_3082
            SIL: SPO1889 SPO3399 SPO3850 SPOA0272
            SIT: TM1040_0040 TM1040_0536
            RSP: RSP_1824(adh) RSP_2576(adhI) RSP_2799 RSP_3537
            RSH: Rsph17029_0472 Rsph17029_1234 Rsph17029_1501
            RSQ: Rsph17025_1947 Rsph17025_3061
            RSK: RSKD131_0130 RSKD131_0888 RSKD131_1169
            RCP: RCAP_rcc00869(adhC)
            JAN: Jann_0044 Jann_3964
            RDE: RD1_0887(flhA) RD1_3806(flhA)
            PDE: Pden_0016 Pden_2367 Pden_4206
            DSH: Dshi_0103(adhI) Dshi_0931(adhA) Dshi_1078
            KVU: EIO_0283(adhC)
            MMR: Mmar10_0803 Mmar10_2836
            HNE: HNE_0560
            HBA: Hbal_2865
            ZMO: ZMO1236 ZMO1596 ZMO1722
            ZMN: Za10_0095 Za10_1498 Za10_1617
            NAR: Saro_0874 Saro_3463
            SAL: Sala_2455 Sala_3073
            SWI: Swit_1179 Swit_1980 Swit_2089 Swit_3018
            SJP: SJA_C1-05070(adh) SJA_C2-02880(adh) SJA_C2-05100(adh)
                 SJA_P1-01350
            ELI: ELI_09625 ELI_11375
            GOX: GOX0313 GOX0314 GOX2018
            ACR: Acry_0843 Acry_2641 Acry_2794
            GDI: GDI_0902(adh) GDI_1852(frmA) GDI_2473(adh)
            GDJ: Gdia_0079 Gdia_0720 Gdia_1118 Gdia_2808
            APT: APA01_00250 APA01_08590 APA01_12700
            RRU: Rru_A0930 Rru_A3405
            RCE: RC1_0269(adhC)
            AZL: AZL_a08020(adh) AZL_c00300(adh) AZL_c02590
            PBR: PB2503_03837
            APB: SAR116_2012
            BSU: BSU26970(adhB) BSU31050(gbsB)
            BSS: BSUW23_12995(adhB) BSUW23_15075(gbsB)
            BHA: BH1829(adhB)
            BAN: BA_2222 BA_2267(adhA) BA_2588 BA_3131(adhB) BA_3566 BA_4599
            BAR: GBAA_2222 GBAA_2267(adhP) GBAA_2588 GBAA_3131(adhB) GBAA_3566
                 GBAA_4599
            BAT: BAS2066 BAS2111(adhP) BAS2412 BAS2912 BAS3306 BAS4267
            BAH: BAMEG_1479 BAMEG_2328 BAMEG_4636
            BAI: BAA_2330 BAA_3180 BAA_4619
            BAL: BACI_c22310 BACI_c30760(adhB2) BACI_c43570
            BCE: BC0802 BC2220(adhA) BC2529 BC3092 BC4365
            BCA: BCE_0198 BCE_0742 BCE_0877 BCE_1099 BCE_2252 BCE_2296(adhA)
                 BCE_2604 BCE_3145(adhB) BCE_3521 BCE_4453
            BCZ: BCZK0168 BCZK0681 BCZK2005(gbsB) BCZK2048(adhB) BCZK2331(adhB)
                 BCZK2838(adhB) BCZK3221 BCZK4115
            BCR: BCAH187_A2378 BCAH187_A3155 BCAH187_A4504 BCAH187_C0241
            BCB: BCB4264_A2248 BCB4264_A3114 BCB4264_A4490
            BCU: BCAH820_2293 BCAH820_3133 BCAH820_4451 BCAH820_B0169
            BCG: BCG9842_B0746 BCG9842_B2124 BCG9842_B3075
            BCQ: BCQ_2203(adhB) BCQ_2941(adhB) BCQ_4155 BCQ_PI181
            BCX: BCA_2350 BCA_3189 BCA_4483
            BCY: Bcer98_0768 Bcer98_1477
            BTK: BT9727_0165 BT9727_2006(gbsB) BT9727_2050(adhB)
                 BT9727_2367(adhB) BT9727_2881(adhB) BT9727_3273 BT9727_4104
            BTL: BALH_0175 BALH_0616 BALH_0714 BALH_1985 BALH_2027(adhA)
                 BALH_2794 BALH_3158 BALH_3956
            BTB: BMB171_C1997 BMB171_C2803 BMB171_C4032 BMB171_P0008
            BWE: BcerKBAB4_2089 BcerKBAB4_4218
            BLI: BL00199 BL02473(adhB) BL02563(gbsB)
            BLD: BLi03269(gbsB) BLi03502 BLi03831(adhB) BLi04290
            BAY: RBAM_003560 RBAM_005890(adhB) RBAM_017440 RBAM_028150(gbsB)
            BAO: BAMF_0303(RBAM_003560) BAMF_0490(adhB) BAMF_1848
                 BAMF_2871(gbsB)
            BAE: BATR1942_01965 BATR1942_20355
            BCL: ABC0046(adhA) ABC0979(gbsB) ABC3413 ABC3428(adhB)
            BPU: BPUM_0237(adhB) BPUM_2350(dhaT) BPUM_2734(gbsB)
            BPF: BpOF4_03860(gfaD) BpOF4_05195(adhB) BpOF4_21519
            BMQ: BMQ_1767 BMQ_3722 BMQ_5107(gbsB)
            BMD: BMD_2194 BMD_3630 BMD_3700 BMD_5094(gbsB)
            BSE: Bsel_1978
            BCO: Bcell_1344 Bcell_1976 Bcell_3340
            OIH: OB2738 OB2801
            GKA: GK0731 GK0938 GK2774
            GTN: GTNG_1754
            GWC: GWCH70_0885
            GYM: GYMC10_2063 GYMC10_2482 GYMC10_4710
            GYC: GYMC61_0742
            GYA: GYMC52_2810
            GCT: GC56T3_0718 GC56T3_2812
            GMC: GY4MC1_1852 GY4MC1_3092 GY4MC1_3718 GY4MC1_3793
            AFL: Aflv_0338(adhA) Aflv_1185(gutB) Aflv_2814
            SAU: SA0143(adhE) SA0562(adh1)
            SAV: SAV0148(adhE) SAV0605(adh1)
            SAW: SAHV_0147(adhE) SAHV_0603(adh1)
            SAH: SaurJH1_0139 SaurJH1_0643(adhA)
            SAJ: SaurJH9_0134 SaurJH9_0628(adhA)
            SAM: MW0123(adhE) MW0568(adh1)
            SAS: SAS0123 SAS0573(adhA)
            SAR: SAR0150(adhE) SAR0613(adhA)
            SAC: SACOL0135 SACOL0237 SACOL0241 SACOL0660(adhP) SACOL2177
                 SACOL2178 SACOL2367
            SAX: USA300HOU_0059(adhC) USA300HOU_0162 USA300HOU_0610(adh)
            SAA: SAUSA300_0055 SAUSA300_0151(adhE) SAUSA300_0250
                 SAUSA300_0594(adh) SAUSA300_2147
            SAO: SAOUHSC_00113 SAOUHSC_00608(adhA)
            SAE: NWMN_0094(adhE) NWMN_0577(adh1)
            SAD: SAAV_0116 SAAV_0569(adhP)
            SAB: SAB0089 SAB0557(adhA) SAB1296c
            SEP: SE0375(adhA) SE0506 SE2098
            SER: SERP0197 SERP0257(adhA) SERP0389 SERP1785 SERP1786 SERP1962
                 SERP2112 SERP2469
            SHA: SH0373(adhC) SH0522
            SSP: SSP0237 SSP1623
            SCA: Sca_2372(adhC)
            SLG: SLGD_02225
            LMO: lmo1634
            LMF: LMOf2365_1656(adhE)
            LMH: LMHCC_0928
            LMC: Lm4b_01645
            LMN: LM5578_1781
            LMY: LM5923_1733
            LIN: lin1675
            LWE: lwe1650
            LSG: lse_1555
            LSP: Bsph_4187
            ESI: Exig_1232 Exig_1536 Exig_2206
            EAT: EAT1b_0155 EAT1b_1799
            MCL: MCCL_1471(adhC)
            BBE: BBR47_08010(adhB) BBR47_46510
            PPY: PPE_00278 PPE_02400 PPE_02875
            PPM: PPSC2_c0332 PPSC2_c3256 PPSC2_c5318
            AAC: Aaci_0919 Aaci_0920 Aaci_2394
            BTS: Btus_1549 Btus_2038
            LLA: L13145(adhE) L190278(ypjA) L55758(adhA)
            LLK: LLKF_1981(adhA) LLKF_2398(adhE)
            LLC: LACR_1641 LACR_1990(adhA) LACR_2457
            LLM: llmg_0955 llmg_1991(adhA) llmg_2432(adhE)
            SPY: SPy_0044(adhA) SPy_1111
            SPZ: M5005_Spy_0039(adh2) M5005_Spy_0040(adhA) M5005_Spy_0834
            SPM: spyM18_0043(adhE) spyM18_0045(adhP) spyM18_1073
            SPG: SpyM3_0036(adh2) SpyM3_0037(adh1) SpyM3_0772
            SPS: SPs0037 SPs0038(adhA) SPs0972
            SPH: MGAS10270_Spy0042 MGAS10270_Spy0043(adhA) MGAS10270_Spy0950
            SPI: MGAS10750_Spy0041 MGAS10750_Spy0042(adhA) MGAS10750_Spy0985
            SPJ: MGAS2096_Spy0041 MGAS2096_Spy0042(adhA) MGAS2096_Spy0043
                 MGAS2096_Spy0044 MGAS2096_Spy0909
            SPK: MGAS9429_Spy0040(adh2) MGAS9429_Spy0041(adhA) MGAS9429_Spy0953
            SPF: SpyM50039(adhE) SpyM50040(adhP) SpyM50954
            SPA: M6_Spy0088 M6_Spy0090(adhA) M6_Spy0832 M6_Spy0833
            SPB: M28_Spy0039 M28_Spy0040(adhA) M28_Spy0811
            SOZ: Spy49_0038(adhE) Spy49_0039(adhP)
            SPN: SP_0285(adhA) SP_1855 SP_2026 SP_2055
            SPD: SPD_0265(adhA) SPD_1636 SPD_1834 SPD_1865
            SPR: spr0262(adhP) spr1670(adhB) spr1837(adhE) spr1866(adh)
            SPW: SPCG_0297(adhP) SPCG_1829(adhB) SPCG_1991(adhE) SPCG_2022(adh)
            SPX: SPG_0268(adhP) SPG_1938
            SNE: SPN23F_02730(adhP) SPN23F_20460(adhE)
            SPV: SPH_0401 SPH_2179 SPH_2210
            SNM: SP70585_0344 SP70585_2111
            SJJ: SPJ_0293 SPJ_2031
            SPP: SPP_0334 SPP_2062
            SNT: SPT_0330 SPT_2021
            SNC: HMPREF0837_10020(adhE) HMPREF0837_10600(adhA)
            SNB: SP670_0357 SP670_2105
            SNP: SPAP_0332 SPAP_2052
            SAG: SAG0053(adhE) SAG0054(adhP) SAG0428
            SAN: gbs0053 gbs0054(adhA) gbs1684
            SAK: SAK_0086 SAK_0087(adhA)
            SMU: SMU.119(adh) SMU.148(adhE) SMU.1867c
            SMC: SmuNN2025_0109 SmuNN2025_0126(adhE)
            STC: str0882 str0936(adhB) str1881 str1882 str1884
            STL: stu0882 stu0936(adhB) stu1881 stu1882 stu1884
            STE: STER_0949
            SSA: SSA_0068(adhE) SSA_0921(adhB) SSA_1917(adh)
            SSU: SSU05_0279(adhA) SSU05_0280 SSU05_1388
            SSV: SSU98_0274(adhA) SSU98_0275 SSU98_1402
            SSB: SSUBM407_0251(adhP) SSUBM407_0252(adhE)
            SSI: SSU0260(adhP) SSU0261(adhE)
            SSS: SSUSC84_0249(adhP) SSUSC84_0250(adhE)
            SGO: SGO_0113(acdH) SGO_0565(adhA) SGO_1774
            SEQ: SZO_00440 SZO_00460
            SEZ: Sez_0043(adh2) Sez_0046(adhA)
            SEU: SEQ_0044 SEQ_0046
            SUB: SUB0063(adhE)
            SDS: SDEG_0061(adh2) SDEG_0062(adhA)
            SGA: GALLO_0220
            SMB: smi_0231(adhE) smi_0275(adhP)
            LPL: lp_1665(adh1) lp_2873(adh2) lp_3662(adhE)
            LPJ: JDM1_2930(adhE)
            LPS: LPST_C2992(adhE)
            LJO: LJ1120 LJ1766
            LJF: FI9785_1548(adhE)
            LAC: LBA0461(adhE) LBA1114
            LSA: LSA0258 LSA0379(adhE) LSA0925(adh) LSA1364 LSA1702(adhA)
            LSL: LSL_1901
            LDE: LDBND_0837
            LBR: LVIS_0119 LVIS_0254(adhA) LVIS_0869
            LCA: LSEI_0775 LSEI_2787
            LCB: LCABL_08380(adhE)
            LCZ: LCAZH_0718
            LGA: LGAS_1561
            LRE: Lreu_0321 Lreu_1496 Lreu_1535 Lreu_1589
            LRF: LAR_0310 LAR_1406 LAR_1444
            LFE: LAF_0277 LAF_1528 LAF_1579
            LRH: LGG_00757(adhE)
            LRL: LC705_00751(adhE)
            LCR: LCRIS_00464(adhE)
            LAM: LA2_02445
            EFA: EF0900(adhE) EF1826(adhA)
            OOE: OEOE_0527 OEOE_1248 OEOE_1330
            LME: LEUM_0146 LEUM_1919
            LCI: LCK_00119(adhE) LCK_00162(adhA)
            LKI: LKI_04135 LKI_04395
            LGS: LEGAS_0220(adhE) LEGAS_0286(adhA)
            CAC: CA_C3375 CA_P0035(adhE) CA_P0162(adhe1)
            CPE: CPE0449(adh) CPE2531(adhE)
            CPF: CPF_0451 CPF_2855(adhE)
            CPR: CPR_0442 CPR_2540
            CTC: CTC01366
            CTH: Cthe_0423
            CDF: CD0334(adhE) CD2843 CD2966(adhE)
            CDC: CD196_0353(adhE) CD196_2753(adhE)
            CDL: CDR20291_0339(adhE) CDR20291_2800(adhE)
            CBO: CBO0345(aad)
            CBA: CLB_0388(adhE)
            CBH: CLC_0403(adhE)
            CBY: CLM_0413(adhE)
            CBL: CLK_3533(adhE)
            CBB: CLD_0407(adhE)
            CBI: CLJ_B0401(adhE)
            CBT: CLH_1998
            CBF: CLI_0416(adhE)
            CBE: Cbei_0305 Cbei_3864
            CKL: CKL_1067 CKL_1614(aad) CKL_2967 CKL_2978 CKL_3000 CKL_3425
            CKR: CKR_0970 CKR_1499 CKR_2631 CKR_2663 CKR_3030
            CPY: Cphy_3925
            CCE: Ccel_3198
            CLJ: CLJU_c16510(adhE1) CLJU_c16520(adhE2) CLJU_c19540
                 CLJU_c35930(dhaT3)
            CSH: Closa_1830 Closa_4287
            CCB: Clocel_2402 Clocel_3267
            AMT: Amet_1657
            STH: STH2049
            AFN: Acfer_0053
            DSY: DSY0565 DSY0623 DSY2755 DSY3044
            DHD: Dhaf_0514 Dhaf_3921 Dhaf_4212
            DRM: Dred_1495 Dred_2277
            DAE: Dtox_1709 Dtox_2962
            PTH: PTH_0606(eutG) PTH_1584
            DAU: Daud_2043
            TJR: TherJR_0855 TherJR_1111
            HMO: HM1_2632(adhE)
            EEL: EUBELI_01490 EUBELI_02054
            ELM: ELI_4403
            EHA: Ethha_1385
            RAL: Rumal_3401
            TMR: Tmar_1863 Tmar_2126
            CLO: HMPREF0868_0538(adh2)
            TTE: TTE0696(eutG)
            TEX: Teth514_0627 Teth514_1935
            TPD: Teth39_0206
            TIT: Thit_2204
            TMT: Tmath_2110
            TBO: Thebr_0212
            CHY: CHY_0925
            MTA: Moth_1911
            ADG: Adeg_1192
            CSC: Csac_0395 Csac_0407 Csac_0711
            ATE: Athe_2244
            CHD: Calhy_0244
            CKI: Calkr_0097
            TOC: Toce_0214
            TTM: Tthe_0472 Tthe_0864 Tthe_2646
            HOR: Hore_02110
            HAS: Halsa_0175 Halsa_1810
            AAR: Acear_0980 Acear_1963
            MAA: MAG_2740 MAG_4280(adhT) MAG_4340(adhT)
            MAL: MAGa4560(adhT)
            MAT: MARTH_orf738(adhA)
            MCD: MCRO_0587(adhT)
            MFR: MFE_06130
            MFM: MfeM64YM_0725(adhT)
            MBV: MBOVPG45_0516(adh-2)
            ACL: ACL_0177
            MTU: Rv0162c(adhE1) Rv0761c(adhB) Rv1530(adh) Rv1862(adhA)
            MTC: MT0171 MT0786 MT1581 MT1911
            MRA: MRA_0170(adhE1) MRA_0771(adhB) MRA_1542(adh) MRA_1873(adhA)
            MTF: TBFG_10163 TBFG_10776 TBFG_11563 TBFG_11890 TBFG_13103
            MTB: TBMG_00163(TBMG_00163.1) TBMG_00776(TBMG_00776.1)
                 TBMG_00881(TBMG_00881.1) TBMG_02132(TBMG_02132.1)
            MBO: Mb0167c(adhE1) Mb0784c(adhB) Mb1557(adh) Mb1893(adhA)
            MBB: BCG_0198c(adhE1) BCG_0813c(adhB) BCG_1582(adh) BCG_1898(adhA)
            MBT: JTY_0168(adhE1) JTY_0783(adhB) JTY_1882(adhA) JTY_3106(adhD)
            MLE: ML2053
            MLB: MLBr_02053
            MPA: MAP0595c(adhB) MAP1571(adhA_1) MAP1613c(adhA_2) MAP3596c(adhE)
            MAV: MAV_0705 MAV_1614 MAV_1943 MAV_2646 MAV_2812 MAV_2857 MAV_4101
                 MAV_5022 MAV_5214
            MSM: MSMEG_0127 MSMEG_0217 MSMEG_0590(rhaD) MSMEG_0671 MSMEG_1138
                 MSMEG_1977 MSMEG_2048 MSMEG_3388 MSMEG_3464 MSMEG_3615
                 MSMEG_3915 MSMEG_4167 MSMEG_5866 MSMEG_6242 MSMEG_6616
                 MSMEG_6833 MSMEG_6834
            MUL: MUL_0470(adhB) MUL_0495(adhX) MUL_2965(adhC) MUL_3015(adhA)
                 MUL_3976
            MVA: Mvan_0443 Mvan_0669 Mvan_3073 Mvan_5164 Mvan_5450
            MGI: Mflv_0236 Mflv_1593 Mflv_3343 Mflv_4626 Mflv_4951
            MAB: MAB_0983c MAB_2041c MAB_4560
            MMC: Mmcs_0111 Mmcs_0137 Mmcs_1096 Mmcs_1713 Mmcs_3405 Mmcs_4585
            MKM: Mkms_0120 Mkms_0513 Mkms_1113 Mkms_1759 Mkms_3468 Mkms_4673
            MJL: Mjls_0101 Mjls_0499 Mjls_1124 Mjls_1690 Mjls_3236 Mjls_3416
                 Mjls_4968
            MSP: Mspyr1_09790 Mspyr1_26740 Mspyr1_43680 Mspyr1_46810
            MMI: MMAR_0127(adhD_1) MMAR_0405(adhE) MMAR_2739(adhA) MMAR_3150
                 MMAR_4110 MMAR_4911(adhX) MMAR_4935(adhB)
            CGL: NCgl0219(cgl0222) NCgl2449(cgl2537) NCgl2709(cgl2807)
            CGB: cg0273 cg3107(adhA)
            CGT: cgR_2695
            CEF: CE0053
            CDI: DIP2114(adhA)
            CUR: cur_1829(adhA)
            CAR: cauri_0635(adhC)
            CPU: cpfrc_01892(adhA)
            NFA: nfa12770 nfa16040 nfa20970 nfa22650 nfa28910 nfa35090 nfa35620
                 nfa38820
            RHA: RHA1_ro00325(adh1) RHA1_ro00447 RHA1_ro00525 RHA1_ro01205
                 RHA1_ro02150 RHA1_ro02497 RHA1_ro02832 RHA1_ro04547
                 RHA1_ro04757 RHA1_ro05321 RHA1_ro06735 RHA1_ro08443
                 RHA1_ro08635 RHA1_ro08965(adh2) RHA1_ro11170(adhB)
            RER: RER_18210 RER_23910(adh) RER_26460 RER_34240 RER_36780
                 RER_54160 RER_56820 pREL1_0257
            ROP: ROP_01120 ROP_09280 ROP_18670 ROP_21220 ROP_22230 ROP_25560
                 ROP_30230 ROP_46300 ROP_48490(adh) ROP_67230 ROP_71160
                 ROP_pROB01-04070 ROP_pROB02-01230
            REQ: REQ_21890 REQ_27350 REQ_29010 REQ_30660 REQ_36070 REQ_36150
                 REQ_44160
            GBR: Gbro_0581 Gbro_3128 Gbro_3529 Gbro_3557 Gbro_3823
            TPR: Tpau_2883 Tpau_3448
            SRT: Srot_0472
            SCO: SCO0199(SCJ12.11c) SCO0259(SCF1.01) SCO7362(SC9H11.16c.)
            SMA: SAV_1141(adhA1) SAV_1357(adhA2) SAV_1393(adhA3) SAV_3833(adhA6)
                 SAV_5335 SAV_5871 SAV_7169
            SGR: SGR_3049 SGR_5208 SGR_5795 SGR_621 SGR_6657
            SCB: SCAB_10681 SCAB_51631 SCAB_58841 SCAB_65591 SCAB_72641
            TWH: TWT326(adh)
            TWS: TW445(adh)
            LXX: Lxx22610(adh)
            CMI: CMM_1256 CMM_2126
            CMS: CMS_1008 CMS_1091
            ART: Arth_0343 Arth_1320 Arth_3087
            AAU: AAur_0342(adhT) AAur_1148 AAur_1866 AAur_3063(adhA)
                 AAur_3716(rhaD) AAur_pTC10058 AAur_pTC20218
            ACH: Achl_1768 Achl_2787
            AAI: AARI_01380 AARI_27050
            KRH: KRH_02680 KRH_07610(adh) KRH_12360(adh)
            MLU: Mlut_21430 Mlut_22590
            RMU: RMDY18_08320
            RDN: HMPREF0733_11029(adhP)
            BCV: Bcav_3663
            BFA: Bfae_07850
            JDE: Jden_1798
            KSE: Ksed_07750 Ksed_22500 Ksed_25570
            XCE: Xcel_2405
            SKE: Sked_00450 Sked_09620
            CFL: Cfla_1049 Cfla_2836
            ICA: Intca_0337 Intca_1887 Intca_3052
            PAC: PPA0539
            PAK: HMPREF0675_3591
            PFR: PFREUD_19130
            NCA: Noca_2363 Noca_3322
            KFL: Kfla_1230 Kfla_7026
            TFU: Tfu_1270 Tfu_1489 Tfu_2771
            NDA: Ndas_1255 Ndas_2247 Ndas_3494
            TCU: Tcur_2022 Tcur_2810 Tcur_4959
            SRO: Sros_0372 Sros_1978 Sros_4103 Sros_4357 Sros_6280 Sros_8254
            FRA: Francci3_0264 Francci3_2514 Francci3_2945
            FRE: Franean1_6571 Franean1_6841
            FRI: FraEuI1c_1885 FraEuI1c_1930 FraEuI1c_3326 FraEuI1c_3514
                 FraEuI1c_4356 FraEuI1c_5104 FraEuI1c_5462 FraEuI1c_5990
                 FraEuI1c_6870
            FAL: FRAAL0199 FRAAL0607 FRAAL1637 FRAAL3122 FRAAL3376(adhC)
                 FRAAL5274(adhC1) FRAAL5467
            ACE: Acel_0138
            NML: Namu_0536 Namu_1805 Namu_3211 Namu_4805
            GOB: Gobs_1750 Gobs_3710 Gobs_4903 Gobs_4948
            KRA: Krad_2224 Krad_2470 Krad_2496 Krad_4297
            SEN: SACE_1535 SACE_2374 SACE_2733 SACE_2738 SACE_2944 SACE_2945
                 SACE_3519(adh) SACE_4085(adh) SACE_4163(adh1) SACE_4519
                 SACE_4852(adh1) SACE_6396
            SVI: Svir_17940
            TBI: Tbis_2709 Tbis_2878
            AMD: AMED_3450(adh) AMED_3504(adh) AMED_4330(adh) AMED_6206
                 AMED_7375(adh) AMED_8391(adh)
            AMI: Amir_1905 Amir_3142 Amir_5014
            STP: Strop_1166 Strop_2600 Strop_2723
            SAQ: Sare_2101 Sare_2799
            MAU: Micau_2032 Micau_2280 Micau_2389 Micau_3246
            MIL: ML5_2392 ML5_2501 ML5_5148
            CAI: Caci_1323 Caci_5895 Caci_8750
            SNA: Snas_0210
            AHE: Arch_0038
            BLO: BL1090 BL1575(adh2)
            BLJ: BLD_1704(putA2)
            BLN: Blon_2241
            BLL: BLJ_1756
            BLB: BBMN68_1612(putA2)
            BAD: BAD_0319
            BLA: BLA_0358(adh)
            BLC: Balac_0378
            BLT: Balat_0378
            BDE: BDP_0426(adh2) BDP_1355(adh3)
            BBI: BBIF_1509(adh3)
            BBP: BBPR_1563(adh2)
            GVA: HMPREF0424_0254(adh)
            GVG: HMPREF0421_20841(adhP) HMPREF0421_21285(adh2)
            RXY: Rxyl_0056 Rxyl_1958 Rxyl_3153
            CWO: Cwoe_3280 Cwoe_4551 Cwoe_5373
            APV: Apar_0629
            ELE: Elen_2478
            OLS: Olsu_0802
            SSM: Spirs_1442 Spirs_3974 Spirs_4083
            LIL: LA_0325(adhP) LA_1616 LA_2361(tdh) LA_2629 LA_3354(adhP)
            LIC: LIC10282 LIC10809(adh) LIC11357 LIC11586 LIC12166
            LBJ: LBJ_2359
            LBL: LBL_0749
            LBI: LEPBI_I1326 LEPBI_I3293
            LBF: LBF_1272(eutG) LBF_3179
            BHY: BHWA1_01827
            BRM: Bmur_1381
            BPO: BP951000_0786 BP951000_1671
            ABA: Acid345_0379 Acid345_3044 Acid345_4584
            ACA: ACP_0589 ACP_3493(adh)
            TSA: AciPR4_1211
            SUS: Acid_1558 Acid_5165 Acid_7928
            BFR: BF1290
            BVU: BVU_0760
            PGN: PGN_0723
            SRU: SRU_0710 SRU_2306
            SRM: SRM_00890(adh) SRM_02533(adh)
            RMR: Rmar_0121
            CHU: CHU_1246(adhP)
            SLI: Slin_3540
            GFO: GFO_1574 GFO_2086
            FJO: Fjoh_4167
            ZPR: ZPR_1705
            CAO: Celal_3017
            FSU: Fisuc_1458
            LBA: Lebu_0601 Lebu_2076
            STR: Sterm_1518 Sterm_3225
            SMF: Smon_0562 Smon_1052
            IPO: Ilyop_0504 Ilyop_1230
            CAA: Caka_0892
            MIN: Minf_0269(adhP) Minf_1850(adhP)
            AMU: Amuc_1911
            GAU: GAU_2688(adh) GAU_2900 GAU_3161
            RBA: RB10805 RB13260(yhdH) RB4131(yjjN) RB5320 RB5856(adh)
            PSL: Psta_4501
            PLM: Plim_2942
            IPA: Isop_0422
            EMI: Emin_0755 Emin_0772
            RSD: TGRD_595
            TAI: Taci_1643
            SYN: sll0990
            SYC: syc1059_d
            SYF: Synpcc7942_0459
            SYG: sync_1463 sync_2669
            SYX: SynWH7803_0877(adhC)
            SYP: SYNPCC7002_A0868
            CYA: CYA_0473(adhE) CYA_0992
            CYB: CYB_0241 CYB_0338
            TEL: tlr0227
            MAR: MAE_21280 MAE_49340
            CYT: cce_1588 cce_4888
            CYP: PCC8801_3587
            CYC: PCC7424_3674 PCC7424_3972 PCC7424_5710
            CYN: Cyan7425_3850 Cyan7425_4034 Cyan7425_4050
            CYH: Cyan8802_2527
            CYJ: Cyan7822_1604 Cyan7822_3027 Cyan7822_3470
            GVI: gll2836 gll4111 glr4425
            ANA: all0879 all2810
            NPU: Npun_R1946
            AVA: Ava_1089 Ava_4482
            NAZ: Aazo_4639
            PMM: PMM1234
            PMB: A9601_14521(adhC)
            TER: Tery_2840
            AMR: AM1_0442 AM1_2463 AM1_D0148
            CTE: CT1275
            CPC: Cpar_1277
            CCH: Cag_0888 Cag_1128 Cag_1710
            CPB: Cphamn1_1084
            PVI: Cvib_0926 Cvib_0955
            PAA: Paes_1246
            RRS: RoseRS_0752 RoseRS_3921
            RCA: Rcas_3224 Rcas_4434
            CAU: Caur_1113 Caur_2281 Caur_2809 Caur_3177
            CAG: Cagg_1718
            CHL: Chy400_1218 Chy400_2455 Chy400_3043 Chy400_3429
            HAU: Haur_4348
            TRO: trd_0582 trd_0767 trd_A0539 trd_A0754 trd_A0843
            STI: Sthe_2859 Sthe_3385
            ATM: ANT_18810(adh)
            DDR: Deide_03550(adh)
            TRA: Trad_0212 Trad_1539 Trad_1794
            TTH: TTC1572
            MSV: Mesil_0116
            AAE: aq_1240(adh2)
            HYA: HY04AAS1_1631
            HTH: HTH_0308
            TAL: Thal_0399
            TMA: TM0111 TM0920
            TPT: Tpet_0007 Tpet_0813
            TLE: Tlet_0180
            TRQ: TRQ2_0836
            TNA: CTN_0580
            TNP: Tnap_0741
            KOL: Kole_1524
            DTH: DICTH_0069 DICTH_0188
            DTU: Dtur_0334 Dtur_0630
            TYE: THEYE_A0694
            TTR: Tter_0303
            DDF: DEFDS_0763 DEFDS_1932
            MMP: MMP0802
            MAC: MA2630(adh)
            MBA: Mbar_A0784
            MMA: MM_2769
            MTP: Mthe_0778
            MRU: mru_1847(adh2)
            HAL: VNG2617G(adh2)
            HMA: pNG7022(adh1) pNG7101(adh8) pNG7103(adh7) pNG7278(adh12)
                 pNG7289(adh6) pNG7314(adhC) pNG7351(adh13) rrnAC0012(adh11)
                 rrnAC0191(adh3) rrnAC1300(adh9) rrnAC1402(adh4) rrnAC1975(adh5)
                 rrnAC2172(adh14) rrnAC3506(adh2)
            HWA: HQ1124A(adh) HQ1729A(adh) HQ2366A(adh) HQ3648A(adh)
            NPH: NP1260A(adh)
            HLA: Hlac_0730 Hlac_1808
            HTU: Htur_2363 Htur_2867 Htur_3740 Htur_4732
            NMG: Nmag_0345 Nmag_3786
            HVO: HVO_2428(adh1)
            HJE: HacjB3_09660 HacjB3_10120
            HBO: Hbor_35490 Hbor_37240 Hbor_38140
            TAC: Ta0832m Ta0841
            TVO: TVN0396 TVN0944 TVN1284
            PTO: PTO0757 PTO0846 PTO1151 PTO1249
            PHO: PH0743
            PFU: PF0075 PF0608
            TKO: TK1008 TK1569
            ABI: Aboo_0352
            APE: APE_1245.1 APE_1557.1 APE_1963.1 APE_2239.1(adh)
            SMR: Smar_0045 Smar_0696 Smar_1072
            SHC: Shell_1406
            DKA: DKAM_1133
            DMU: Desmu_1135
            TAG: Tagg_0918
            IAG: Igag_1026
            SSO: SSO0764(adh-2) SSO1220(adh-3) SSO1646(adh-5) SSO2494(adh-8)
                 SSO2536(adh-10) SSO2878(adh-13)
            STO: ST0038 ST0053 ST0075 ST0480 ST2577
            SAI: Saci_0911(adh) Saci_1115(adh) Saci_2057 Saci_2126(adh)
                 Saci_2205 Saci_2224(adh)
            SIS: LS215_0432
            SIA: M1425_0848
            SIM: M1627_0913
            SID: M164_0412 M164_0866
            SIY: YG5714_0392
            SIN: YN1551_2043 YN1551_2663
            SII: LD85_0297 LD85_0423 LD85_0979
            MSE: Msed_0398 Msed_0464 Msed_1426
            PAI: PAE1921 PAE2051 PAE2332 PAE2931
            PIS: Pisl_0338 Pisl_0639 Pisl_1601 Pisl_1770 Pisl_1949
            PCL: Pcal_0882 Pcal_1311 Pcal_1581
            PAS: Pars_0396 Pars_0547 Pars_1545 Pars_2114
            CMA: Cmaq_1175 Cmaq_1719
            VDI: Vdis_0262 Vdis_1460
            TPE: Tpen_1006 Tpen_1516
            NMR: Nmar_0523 Nmar_1193
            CSY: CENSYa_0510 CENSYa_1407
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.1
            IUBMB Enzyme Nomenclature: 1.1.1.1
            ExPASy - ENZYME nomenclature database: 1.1.1.1
            UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.1
            BRENDA, the Enzyme Database: 1.1.1.1
            CAS: 9031-72-5
///
ENTRY       EC 1.1.1.2                  Enzyme
NAME        alcohol dehydrogenase (NADP+);
            aldehyde reductase (NADPH2);
            NADP-alcohol dehydrogenase;
            NADP+-aldehyde reductase;
            NADP+-dependent aldehyde reductase;
            NADPH-aldehyde reductase;
            NADPH-dependent aldehyde reductase;
            nonspecific succinic semialdehyde reductase;
            ALR 1;
            low-Km aldehyde reductase;
            high-Km aldehyde reductase;
            alcohol dehydrogenase (NADP)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     alcohol:NADP+ oxidoreductase
REACTION    an alcohol + NADP+ = an aldehyde + NADPH + H+ [RN:R07328]
ALL_REAC    R07328 > R00625 R00746 R01041 R05231
SUBSTRATE   alcohol [CPD:C00069];
            NADP+ [CPD:C00006]
PRODUCT     aldehyde [CPD:C00071];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COFACTOR    Zinc [CPD:C00038]
COMMENT     A zinc protein. Some members of this group oxidize only primary
            alcohols; others act also on secondary alcohols. May be identical
            with EC 1.1.1.19 (L-glucuronate reductase), EC 1.1.1.33 [mevaldate
            reductase (NADPH)] and EC 1.1.1.55 [lactaldehyde reductase (NADPH)].
            A-specific with respect to NADPH.
REFERENCE   1  [PMID:4402936]
  AUTHORS   Bosron WF, Prairie RL.
  TITLE     Triphosphopyridine nucleotide-linked aldehyde reductase. I.
            Purification and properties of the enzyme from pig kidney cortex.
  JOURNAL   J. Biol. Chem. 247 (1972) 4480-5.
  ORGANISM  Sus scrofa [GN:ssc]
REFERENCE   2
  AUTHORS   DeMoss, R.
  TITLE     Triphosphopyridine nucleotide-specific ethanol dehydrogenase from
            Leuconostoc mesenteroides.
  JOURNAL   Bacteriol. Proc. (1953) 81.
REFERENCE   3
  AUTHORS   Reeves, R.E., Montalvo, F.E. and Lushbaugh, T.S.
  TITLE     Nicotinamide-adenine dinucleotide phosphate-dependent alcohol
            dehydrogenase. Enzyme from Entamoeba histolytica and some enzyme
            inhibitors.
  JOURNAL   Int. J. Biochem. 2 (1971) 55-64.
REFERENCE   4  [PMID:4393513]
  AUTHORS   Tabakoff B, Erwin VG.
  TITLE     Purification and characterization of a reduced nicotinamide adenine
            dinucleotide phosphate-linked aldehyde reductase from brain.
  JOURNAL   J. Biol. Chem. 245 (1970) 3263-8.
  ORGANISM  Bos taurus [GN:bta]
PATHWAY     ec00010  Glycolysis / Gluconeogenesis
            ec00561  Glycerolipid metabolism
            ec00930  Caprolactam degradation
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00002  alcohol dehydrogenase (NADP+)
GENES       HSA: 10327(AKR1A1)
            PTR: 741418(AKR1A1)
            PON: 100173796(AKR1A1)
            MCC: 693380(AKR1A1)
            MMU: 58810(Akr1a4)
            RNO: 78959(Akr1a1)
            CFA: 610537
            AML: 100466911
            BTA: 618607(AKR1A1)
            SSC: 396924(AKR1A1)
            ECB: 100052360
            MDO: 100024617
            OAA: 100076515
            GGA: 424599(AKR1A1)
            TGU: 100220342
            XLA: 444488(akr1a1)
            XTR: 548891(akr1a1)
            DRE: 799805(akr1a1b)
            SPU: 587281
            DME: Dmel_CG2767
            NVE: NEMVE_v1g181888
            HMG: 100204444
            TAD: TRIADDRAFT_29280
            OSA: 4338987
            CME: CMM296C
            SCE: YCR105W(ADH7) YMR318C(ADH6)
            KLA: KLLA0E19889g
            LTH: KLTH0B04972g KLTH0E07964g
            PPA: PAS_chr1-1_0357 PAS_chr4_0576
            VPO: Kpol_1057p24 Kpol_257p4 Kpol_526p18 Kpol_529p30
            ZRO: ZYRO0G10318g
            CGR: CAGL0H06853g CAGL0M14047g
            DHA: DEHA2C04510g DEHA2C17666g
            PIC: PICST_29079(ADH4) PICST_31312(ADH5) PICST_45137(ADH7)
            PGU: PGUG_05188
            LEL: LELG_04799
            CAL: CaO19.12963(ADH7)
            CTP: CTRG_02797
            CDU: CD36_62710
            CLU: CLUG_03198 CLUG_03199 CLUG_03797
            NCR: NCU04823 NCU11179
            PAN: PODANSg2904 PODANSg4584
            MGR: MGG_00220(MG00220.4) MGG_06489(MG06489.4) MGG_11818(MG06833.4)
            FGR: FG06619.1 FG08980.1
            SSL: SS1G_00401 SS1G_07135
            BFU: BC1G_00717 BC1G_10210
            ANI: AN2860.2
            AFM: AFUA_1G09750 AFUA_3G11900 AFUA_6G10260
            NFI: NFIA_065400
            AOR: AO090003000751 AO090023000460
            AFV: AFLA_030660
            ACT: ACLA_039770
            PCS: Pc18g00530
            PNO: SNOG_15556
            CNE: CNC05140 CNK02370
            CNB: CNBC2030
            PPL: POSPLDRAFT_106595
            UMA: UM01861.1
            EHI: EHI_023110(81.t00034) EHI_039190(73.t00013)
                 EHI_198760(34.t00053)
            EDI: EDI_307670
            TET: TTHERM_00274500
            TCR: 504339.19 504425.60 508677.80 509331.210
            LMA: LmjF23.0360
            TVA: TVAG_344880
            PTI: PHATRDRAFT_41470
            TPS: THAPSDRAFT_40021
            XFA: XF1136 XF1727 XF1734
            XFT: PD0423(adhP)
            PST: PSPTO_2182
            PSB: Psyr_1992
            PSP: PSPPH_1961
            CBD: CBUD_1937
            CBG: CbuG_1847
            ABO: ABO_2414(AKR1A1)
            RSO: RSc0632
            HPJ: jhp1429
            ABU: Abu_0783
            ATU: Atu2022(adh)
            MSM: MSMEG_2317
            CGL: NCgl0324(cgl0331)
            CGB: cg0400(adhC)
            CGT: cgR_0413
            CEF: CE0338
            CJK: jk2055(adhA)
            KRH: KRH_19860(adhC)
            PAC: PPA1072
            SEN: SACE_2652
            LIL: LA_3172(ara1)
            LIC: LIC10949(dkgA)
            PPN: Palpr_2608
            SRU: SRU_1267
            SRM: SRM_01456
            MTT: Ftrac_3685
            GFO: GFO_1874
            ZPR: ZPR_1868
            CAT: CA2559_11288
            SYN: slr0942
            SYG: sync_0822
            CYT: cce_0782
            MAC: MA0403
            MBA: Mbar_A0771
            MST: Msp_0967(adh)
            HMA: pNG7101(adh8)
            HWA: HQ1729A(adh)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.2
            IUBMB Enzyme Nomenclature: 1.1.1.2
            ExPASy - ENZYME nomenclature database: 1.1.1.2
            BRENDA, the Enzyme Database: 1.1.1.2
            CAS: 9028-12-0
///
ENTRY       EC 1.1.1.3                  Enzyme
NAME        homoserine dehydrogenase;
            HSDH;
            HSD
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-homoserine:NAD(P)+ oxidoreductase
REACTION    L-homoserine + NAD(P)+ = L-aspartate 4-semialdehyde + NAD(P)H + H+
            [RN:R01773 R01775]
ALL_REAC    R01773 R01775
SUBSTRATE   L-homoserine [CPD:C00263];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     L-aspartate 4-semialdehyde [CPD:C00441];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     The yeast enzyme acts most rapidly with NAD+; the Neurospora enzyme
            with NADP+. The enzyme from Escherichia coli is a multi-functional
            protein, which also catalyses the reaction of EC 2.7.2.4 (aspartate
            kinase).
REFERENCE   1  [PMID:14353905]
  AUTHORS   BLACK S, WRIGHT NG.
  TITLE     Homoserine dehydrogenase.
  JOURNAL   J. Biol. Chem. 213 (1955) 51-60.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
REFERENCE   2  [PMID:4551091]
  AUTHORS   Starnes WL, Munk P, Maul SB, Cunningham GN, Cox DJ, Shive W.
  TITLE     Threonine-sensitive aspartokinase-homoserine dehydrogenase complex,
            amino acid composition, molecular weight, and subunit composition of
            the complex.
  JOURNAL   Biochemistry. 11 (1972) 677-87.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   3  [PMID:4562990]
  AUTHORS   Veron M, Falcoz-Kelly F, Cohen GN.
  TITLE     The threonine-sensitive homoserine dehydrogenase and aspartokinase
            activities of Escherichia coli K12. The two catalytic activities are
            carried by two independent regions of the polypeptide chain.
  JOURNAL   Eur. J. Biochem. 28 (1972) 520-7.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00260  Glycine, serine and threonine metabolism
            ec00270  Cysteine and methionine metabolism
            ec00300  Lysine biosynthesis
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00003  homoserine dehydrogenase
            K12524  bifunctional aspartokinase / homoserine dehydrogenase 1
            K12525  bifunctional aspartokinase / homoserine dehydrogenase 2
GENES       NVE: NEMVE_v1g225948
            ATH: AT1G31230 AT4G19710(AK-HSDH_II)
            POP: POPTR_288174 POPTR_780515
            RCU: RCOM_0742100
            VVI: 100258602
            OSA: 4345328 4346642
            SBI: SORBI_02g019450
            ZMA: 542249(umc1175) 542708(akh2)
            PPP: PHYPADRAFT_131376 PHYPADRAFT_142581
            CRE: CHLREDRAFT_196925(AHD1)
            VCN: VOLCADRAFT_73076(ahd1)
            OLU: OSTLU_16870
            OTA: Ot09g03610
            CME: CMN129C
            SCE: YJR139C(HOM6)
            AGO: AGOS_ABL080W
            KLA: KLLA0B03872g
            LTH: KLTH0D17446g
            PPA: PAS_chr1-4_0049
            VPO: Kpol_1024p2
            ZRO: ZYRO0B08756g
            CGR: CAGL0M00330g
            DHA: DEHA2F01298g
            PIC: PICST_57619(HOM6)
            PGU: PGUG_03982
            LEL: LELG_01600
            CAL: CaO19.10468(HOM6)
            CTP: CTRG_04629
            CDU: CD36_02440
            YLI: YALI0D01089g
            CLU: CLUG_01603
            NCR: NCU03935
            PAN: PODANSg3030
            MGR: MGG_11450
            FGR: FG09284.1
            SSL: SS1G_14424
            BFU: BC1G_09640
            ANI: AN2882.2
            AFM: AFUA_3G11640
            NFI: NFIA_065670
            AOR: AO090003000721 AO090009000136
            ANG: An02g07430
            AFV: AFLA_030970 AFLA_053200
            ACT: ACLA_039530
            PCS: Pc13g08990
            CIM: CIMG_03660
            CPW: CPC735_006180
            URE: UREG_07422
            PNO: SNOG_08379
            TML: GSTUM_00009048001
            SPO: SPBC776.03
            CNE: CNJ02040
            CNB: CNBJ1420
            LBC: LACBIDRAFT_238324
            MPR: MPER_05297
            CCI: CC1G_07739
            SCM: SCHCODRAFT_79193
            UMA: UM01708.1
            MGL: MGL_2414
            LMA: LmjF07.0260
            LIF: LinJ07.0240
            LBZ: LbrM07_V2.0270
            PTI: PHATRDRAFT_22113
            TPS: THAPS_29008
            PIF: PITG_12514
            ECO: b0002(thrA) b3940(metL)
            ECJ: JW0001(thrA) JW3911(metL)
            ECD: ECDH10B_0002(thrA) ECDH10B_4129(metL)
            EBW: BWG_0002(thrA) BWG_3609(metL)
            ECE: Z0002(thrA) Z5495(metL)
            ECS: ECs0002(thrA) ECs4869(metL)
            ECF: ECH74115_0003(thrA) ECH74115_5400(metL)
            ETW: ECSP_0002(thrA) ECSP_5010(metL)
            EOJ: ECO26_0002(thrA) ECO26_4644(metL)
            EOI: ECO111_0002(thrA) ECO111_4766(metL)
            EOH: ECO103_0002(thrA) ECO103_4697(metL)
            ECG: E2348C_0002(thrA) E2348C_4244(metL)
            EOK: G2583_0002(thrA) G2583_4752(metL)
            ECC: c0003(thrA) c4893(metL)
            ECP: ECP_0002(thrA) ECP_4149(metL)
            ECI: UTI89_C0002(thrA) UTI89_C4525(metL)
            ECV: APECO1_1976(thrA) APECO1_2531(metL)
            ECX: EcHS_A0003(thrA) EcHS_A4174(metL)
            ECW: EcE24377A_0001(thrA) EcE24377A_4480(metL)
            ECM: EcSMS35_0001(thrA) EcSMS35_4382(metL)
            ECY: ECSE_0002(thrA) ECSE_4234(metL)
            ECR: ECIAI1_0002(thrA) ECIAI1_4149(metL)
            ECQ: ECED1_0001(thrA) ECED1_4643(metL)
            ECK: EC55989_0002(thrA) EC55989_4422(metL)
            ECT: ECIAI39_0001(thrA) ECIAI39_3054(metL)
            EUM: ECUMN_0002(thrA) ECUMN_4470(metL)
            ECZ: ECS88_0002(thrA) ECS88_4391(metL)
            ECL: EcolC_3653(thrA) EcolC_4075(metL)
            EBR: ECB_00002(thrA) ECB_03826(metL)
            EBD: ECBD_3616(thrA) ECBD_4083(metL)
            EFE: EFER_0001(thrA) EFER_3831(metL)
            STY: STY0002(thrA) STY3768(metL)
            STT: t0002(thrA) t3517(metL)
            STM: STM0002(thrA) STM4101(metL)
            SPT: SPA0002(thrA) SPA3944(metL)
            SEK: SSPA0002(thrA) SSPA3671(metL)
            SPQ: SPAB_00002(thrA) SPAB_05082(metL)
            SEI: SPC_0002(thrA) SPC_4210(metL)
            SEC: SC0002(thrA) SC3992(metL)
            SEH: SeHA_C0002(thrA) SeHA_C4435(metL)
            SEE: SNSL254_A0002(thrA) SNSL254_A4432(metL)
            SEW: SeSA_A0002(thrA) SeSA_A4318(metL)
            SEA: SeAg_B0002(thrA) SeAg_B4348(metL)
            SED: SeD_A0002(thrA) SeD_A4502(metL)
            SEG: SG0002(thrA) SG3319(metL)
            SET: SEN0001(thrA) SEN3891(metL)
            SES: SARI_02990(thrA) SARI_03555(metL)
            YPE: YPO0116(metL) YPO0459(thrA)
            YPK: y0303(metL) y3718(thrA)
            YPA: YPA_0265(metL) YPA_4051(thrA)
            YPN: YPN_0331(thrA) YPN_3738
            YPM: YP_0118(metL) YP_3723(thrA)
            YPP: YPDSF_3174(thrA) YPDSF_3791(metL)
            YPG: YpAngola_A0808(thrA) YpAngola_A3806(metL)
            YPZ: YPZ3_0099(metL) YPZ3_0446(thrA)
            YPS: YPTB0106(metL) YPTB0602(thrA)
            YPI: YpsIP31758_0122(metL) YpsIP31758_3476(thrA)
            YPY: YPK_3604(thrA) YPK_4094(metL)
            YPB: YPTS_0109(metL) YPTS_0626(thrA)
            YEN: YE0112(metL) YE0600(thrA)
            SFL: SF0002(thrA) SF4018(metL)
            SFX: S0002(thrA) S3729(metL)
            SFV: SFV_0001(thrA) SFV_4010(metL)
            SSN: SSON_0002(thrA) SSON_4114(metL)
            SBO: SBO_0001(thrA) SBO_3960(metL)
            SBC: SbBS512_E0002(thrA) SbBS512_E4426(metL)
            SDY: SDY_0002(thrA) SDY_3775(metL)
            ECA: ECA3891(thrA) ECA4251(metL)
            PCT: PC1_0178 PC1_3668
            PWA: Pecwa_0190(metL) Pecwa_3863(thrA)
            ETA: ETA_01280(metL) ETA_06980(thrA)
            EPY: EpC_01510(metL) EpC_06860(thrA)
            EAM: EAMY_0139(metL) EAMY_2951(thrA)
            EAY: EAM_0134(metL) EAM_0642(thrA)
            EBI: EbC_01650(metL) EbC_06600(thrA)
            PLU: plu0563(thrA) plu4755(metL)
            PAY: PAU_00533(thrA) PAU_04243(metL)
            BUC: BU194(thrA)
            BAS: BUsg188(thrA)
            BAB: bbp183(thrA)
            BCC: BCc_127(thrA)
            BAP: BUAP5A_191(thrA)
            BAU: BUAPTUC7_193(thrA)
            WBR: WGLp591(thrA)
            SGL: SG0404(thrA)
            ENT: Ent638_0564(thrA) Ent638_4034(metL)
            ENC: ECL_00814 ECL_05038
            ESC: Entcl_3716 Entcl_4334
            ESA: ESA_03335(thrA) ESA_03821(metL)
            CTU: Ctu_01810(metL) Ctu_06300(thrA)
            KPN: KPN_00002(thrA) KPN_04234(metL)
            KPE: KPK_4755(thrA) KPK_5445(metL)
            KPU: KP1_0096(metL) KP1_0820(thrA)
            KVA: Kvar_4392 Kvar_4984
            CKO: CKO_03054(metL) CKO_03385(thrA)
            CRO: ROD_00011(thrA) ROD_38031(metL)
            SPE: Spro_0683(thrA) Spro_4785(metL)
            PMR: PMI0001(thrA) PMI3224(metL)
            EIC: NT01EI_0659(thrA) NT01EI_3806(metL)
            ETR: ETAE_0565(thrA) ETAE_3429
            BFL: Bfl111(thrA)
            BPN: BPEN_115(thrA)
            BVA: BVAF_112(thrA)
            HDE: HDEF_1900(thrA)
            DDA: Dd703_0572(thrA) Dd703_3790(metL)
            DDC: Dd586_3603 Dd586_3932
            DDD: Dda3937_00394(thrA) Dda3937_03889(metL)
            DZE: Dd1591_0121(metL) Dd1591_0533(thrA)
            XBO: XBJ1_3515(thrA) XBJ1_4276(metL)
            XNE: XNC1_0228(metL) XNC1_0692(thrA)
            PAM: PANA_0655(thrA) PANA_3848(metL)
            PVA: Pvag_0062(thrA) Pvag_3138(metL)
            PAO: Pat9b_0608 Pat9b_3858
            RIP: RIEPE_0545
            HIN: HI0089(thrA)
            HIT: NTHI0167(thrA)
            HIP: CGSHiEE_02840(thrA)
            HIF: HIBPF01310(thrA)
            HIL: HICON_03620
            HAP: HAPS_1271(thrA)
            HSO: HS_1214(thrA)
            HSM: HSM_0349(thrA)
            PMU: PM0113(thrA)
            MSU: MS1703(thrA)
            APL: APL_0250(thrA)
            APA: APP7_0252(thrA)
            ASU: Asuc_0801(thrA)
            AAT: D11S_1497(thrA)
            XFA: XF2225(thrA)
            XFT: PD1273(thrA)
            XFM: Xfasm12_1425(thrA)
            XFN: XfasM23_1358(thrA)
            XCC: XCC1800(thrA) XCC2855
            XCB: XC_1253 XC_2389(thrA)
            XCA: xccb100_1299 xccb100_2087(thrA)
            XCV: XCV1866(thrA) XCV3175(metL)
            XAC: XAC1820(thrA) XAC3038
            XOO: XOO1820 XOO2242(thrA)
            XOM: XOO_1718 XOO_2107(thrA)
            XOP: PXO_00814(thrA) PXO_01682
            XAL: XALc_1240(thrA) XALc_2184
            SML: Smlt2156(thrA) Smlt3633(thrA)
            SMT: Smal_1749(thrA) Smal_3049
            PSU: Psesu_0760 Psesu_1249
            VCH: VC2364(thrA) VC2684(metL)
            VCO: VC0395_A1943(thrA) VC0395_A2257(metL)
            VCM: VCM66_2287(thrA) VCM66_2604(metL)
            VCJ: VCD_001684(metL) VCD_001985(thrA)
            VVU: VV1_0545(thrA) VV1_1365(metL)
            VVY: VV0650(thrA) VV3007(metL)
            VVM: VVM_00582 VVM_04124
            VPA: VP0494(thrA) VP2764(metL)
            VHA: VIBHAR_00048(metL) VIBHAR_00939(thrA)
            VSP: VS_0483(thrA) VS_2893(metL)
            VEX: VEA_002307 VEA_004457
            VFI: VF_2118(thrA) VF_2266(metL)
            VFM: VFMJ11_2224(thrA) VFMJ11_2378(metL)
            VSA: VSAL_I2556(thrA) VSAL_I2748(metL)
            PPR: PBPRA0262(metL) PBPRA0552(thrA)
            PAE: PA3736(hom)
            PAU: PA14_16070(hom)
            PAP: PSPA7_1383(hom)
            PAG: PLES_12441(hom)
            PPU: PP_0664 PP_1470(hom)
            PPF: Pput_0698 Pput_4251
            PPG: PputGB1_1075
            PPW: PputW619_4149
            PST: PSPTO_1480(hom)
            PSB: Psyr_1290
            PSP: PSPPH_1360(hom)
            PFL: PFL_1103(hom) PFL_3809(hom)
            PFO: Pfl01_1027
            PFS: PFLU2011 PFLU5006
            PEN: PSEEN4252(hom)
            PMY: Pmen_2012 Pmen_3394
            PSA: PST_1198(hom)
            CJA: CJA_1439(hom)
            AVN: Avin_39490(hom)
            PAR: Psyc_0253(hom)
            PCR: Pcryo_0279
            PRW: PsycPRwf_2010
            ACI: ACIAD0264(hom)
            ACD: AOLE_10205 AOLE_18210
            ACB: A1S_0239 A1S_1711
            ABM: ABSDF1940 ABSDF3294(hom)
            ABY: ABAYE1937 ABAYE3530(hom)
            ABC: ACICU_00262 ACICU_01746
            ABN: AB57_0328 AB57_1939
            ABB: ABBFA_001785 ABBFA_003293
            MCT: MCR_0488
            SON: SO_3415(thrA) SO_4055(metL)
            SDN: Sden_0616(metL) Sden_2740(thrA)
            SFR: Sfri_2906(thrA) Sfri_3550(metL)
            SAZ: Sama_0905(thrA) Sama_3170(metL)
            SBL: Sbal_1227(thrA) Sbal_3775
            SBM: Shew185_0537(metL) Shew185_1271(thrA)
            SBN: Sbal195_0561(metL) Sbal195_1304(thrA)
            SBP: Sbal223_0565(metL) Sbal223_3086(thrA)
            SLO: Shew_0521 Shew_1079(thrA)
            SPC: Sputcn32_0617(metL) Sputcn32_2735(thrA)
            SSE: Ssed_1175(thrA) Ssed_4040(metL)
            SPL: Spea_0561(metL) Spea_1066(thrA)
            SHE: Shewmr4_1138(thrA) Shewmr4_3438(metL)
            SHM: Shewmr7_0513(metL) Shewmr7_1209(thrA)
            SHN: Shewana3_1139(thrA) Shewana3_3613(metL)
            SHW: Sputw3181_1277(thrA) Sputw3181_3553
            SHL: Shal_0623(metL) Shal_1114(thrA)
            SWD: Swoo_0623(metL) Swoo_1270(thrA)
            SWP: swp_3750(thrA) swp_4556(metL)
            SVO: SVI_0975(thrA) SVI_3739(metL)
            ILO: IL2466(metL)
            CPS: CPS_0456(metL) CPS_4291(thrA)
            PHA: PSHAa2379(thrA) PSHAa2722(metL)
            PAT: Patl_3580(thrA)
            PSM: PSM_A0303 PSM_A0697(thrA)
            SDE: Sde_1209
            MAQ: Maqu_2274
            AMC: MADE_03328(thrA)
            PIN: Ping_1275(thrA)
            TTU: TERTU_0469 TERTU_1164
            FBL: Fbal_0766 Fbal_3512
            MCA: MCA0597(hom)
            FTW: FTW_1648
            FTA: FTA_0521
            FTM: FTM_0581(thrA)
            FTN: FTN_0525(thrA)
            FPH: Fphi_0313
            TCX: Tcr_1251
            NOC: Noc_2454
            NHL: Nhal_0725
            NWA: Nwat_0680
            ALV: Alvin_2123
            AEH: Mlg_1822
            HHA: Hhal_0125
            TGR: Tgr7_1439
            TKM: TK90_1281
            HNA: Hneap_1393
            HCH: HCH_01779(thrA)
            CSA: Csal_3010
            HEL: HELO_3857(hom)
            ABO: ABO_0806(hom)
            KKO: Kkor_1611
            MMW: Mmwyl1_3765
            AHA: AHA_0590(metL) AHA_3018(thrA)
            ASA: ASA_3040(thrA) ASA_3796(metL)
            TAU: Tola_0129(metL) Tola_0621(thrA)
            AFE: Lferr_0633
            AFR: AFE_0473(metM)
            CRP: CRP_121
            RMA: Rmag_0769
            VOK: COSY_0706(thrA)
            GPB: HDN1F_22460(thrA)
            NMA: NMA1395(hom)
            NME: NMB1228(metM)
            NMC: NMC1128(hom)
            NMN: NMCC_1109(hom)
            NMI: NMO_1040(hom)
            NGO: NGO0779
            NGK: NGK_1097
            NLA: NLA_10340(hom)
            CVI: CV_0996(metL)
            LHK: LHK_00589(metL)
            RSO: RSc1327
            RSC: RCFBP_20099(hom)
            RSL: RPSI07_2040(hom)
            RPI: Rpic_1202
            RPF: Rpic12D_1263
            REU: Reut_A1993
            REH: H16_A2266(thrA)
            RME: Rmet_1966
            CTI: RALTA_A1810(hom)
            BMA: BMA1385(hom)
            BMV: BMASAVP1_A1875(hom)
            BML: BMA10229_A0022(hom)
            BMN: BMA10247_1147(hom)
            BPS: BPSL1477(hom)
            BPM: BURPS1710b_2396(hom)
            BPL: BURPS1106A_2270(hom)
            BPD: BURPS668_2232(hom)
            BPR: GBP346_A2340
            BTE: BTH_I2198
            BVI: Bcep1808_1781
            BUR: Bcep18194_A5155
            BCN: Bcen_6225
            BCH: Bcen2424_1854
            BCM: Bcenmc03_1878 Bcenmc03_6797
            BCJ: BCAL1926(hom)
            BAM: Bamb_1792 Bamb_4289
            BAC: BamMC406_1764 BamMC406_4844
            BMU: Bmul_1419
            BMJ: BMULJ_01824(thrA)
            BXE: Bxe_A2381
            BPH: Bphy_0931
            BPY: Bphyt_1806
            BGL: bglu_1g14150 bglu_2g03030
            BGE: BC1002_1378
            BRH: RBRH_03674
            PNU: Pnuc_0438
            PNE: Pnec_0445
            BPE: BP2784
            BPA: BPP2479
            BBR: BB1926
            BPT: Bpet2747(hom)
            BAV: BAV2163(hom)
            AXY: AXYL_01901(hom)
            TEQ: TEQUI_1322
            RFR: Rfer_1912
            POL: Bpro_2190 Bpro_5333
            PNA: Pnap_2231
            AAV: Aave_0011 Aave_1238
            AJS: Ajs_3206 Ajs_4155
            DIA: Dtpsy_0012 Dtpsy_2559
            VEI: Veis_2663
            DAC: Daci_5219
            VAP: Vapar_1831
            VPE: Varpa_2093
            CTT: CtCNB1_1023
            ADN: Alide_0015 Alide_3272
            MPT: Mpe_A1541
            HAR: HEAR2150(hom)
            MMS: mma_1312(thrA)
            HSE: Hsero_2094(thrA)
            LCH: Lcho_2025
            TIN: Tint_2112
            NEU: NE2369
            NET: Neut_0865
            NMU: Nmul_A1551
            EBA: ebA4952(thrA)
            AZO: azo2081(hom)
            DAR: Daro_2386
            TMZ: Tmz1t_2578
            TBD: Tbd_0843
            MFA: Mfla_0904 Mfla_1048
            MMB: Mmol_1533
            MEH: M301_1100
            MEI: Msip34_0875
            MEP: MPQ_0912(thrA)
            APP: CAP2UW1_0892
            SLT: Slit_2218
            GCA: Galf_1820
            HPY: HP0822
            HPJ: jhp0761(hom)
            HPA: HPAG1_0808
            HPS: HPSH_02695
            HPG: HPG27_781(uvrC)
            HPP: HPP12_0829(hom)
            HPB: HELPY_0534(hom)
            HPL: HPB8_1031(thrA)
            HPC: HPPC_04160
            HPM: HPSJM_04165
            HHE: HH1750(hom)
            HAC: Hac_0726(hom)
            HMS: HMU09790(hom)
            HFE: Hfelis_14750
            WSU: WS0450(HOM)
            TDN: Suden_1904
            SKU: Sulku_2298
            CJE: Cj0149c(hom)
            CJR: CJE0145(hom)
            CJJ: CJJ81176_0185(hom)
            CJU: C8J_0146(hom)
            CJN: ICDCCJ_146
            CJD: JJD26997_0164(hom)
            CFF: CFF8240_0293
            CCV: CCV52592_0834
            CHA: CHAB381_0217
            CCO: CCC13826_1144
            CLA: Cla_1414(hom)
            ABU: Abu_0158(hom)
            ANT: Arnit_0167
            SDL: Sdel_0169
            NIS: NIS_1553
            SUN: SUN_0225
            NSA: Nitsa_1850
            NAM: NAMH_0468
            GSU: GSU1693(hom)
            GME: Gmet_1629
            GUR: Gura_2178
            GLO: Glov_1214
            GBM: Gbem_3019(hom)
            GEO: Geob_2680
            GEM: GM21_1231
            PCA: Pcar_1451
            PPD: Ppro_1294
            DVU: DVU0890(hom)
            DVL: Dvul_2094
            DVM: DvMF_1412
            DDE: Dde_2731
            DDS: Ddes_2314
            DMA: DMR_28990(hom)
            DSA: Desal_2440
            DAS: Daes_1439
            DBA: Dbac_3388
            DRT: Dret_1929
            DPS: DP1732
            DAK: DaAHT2_0885
            DPR: Despr_2571
            DOL: Dole_0291
            DAL: Dalk_0711
            DAT: HRM2_13560(hom)
            ADE: Adeh_1638 Adeh_3931
            ACP: A2cp1_2310 A2cp1_4072
            AFW: Anae109_2173
            ANK: AnaeK_2222 AnaeK_4040
            MXA: MXAN_0971 MXAN_2278
            SCL: sce4845(hom)
            HOH: Hoch_2251
            SAT: SYN_00890
            SFU: Sfum_1218
            DBR: Deba_1382
            PUB: SAR11_0852 SAR11_1025(hom)
            MLO: mll0934
            MCI: Mesci_4216
            MES: Meso_1922
            PLA: Plav_2946
            SME: SMc00293(thrA)
            SMD: Smed_1453
            RHI: NGR_b07030(thrA) NGR_c14020(thrA)
            ATU: Atu1588(hom)
            ARA: Arad_2162(thrA)
            AVI: Avi_2279(hom)
            RET: RHE_CH01878(thrA)
            REC: RHECIAT_CH0001964(thrA)
            RLE: RL2097(hom) pRL80071(hom)
            RLT: Rleg2_1545 Rleg2_5063
            RLG: Rleg_1739
            LAS: CLIBASIA_03995(thrA)
            LSO: CKC_04665
            BME: BMEI0725
            BMI: BMEA_A1320
            BMF: BAB1_1293
            BMB: BruAb1_1275(hom)
            BMC: BAbS19_I12070
            BMS: BR1274(hom)
            BMT: BSUIS_A1323
            BOV: BOV_1237(hom)
            BCS: BCAN_A1295
            BMR: BMI_I1285(hom)
            OAN: Oant_1917
            BJA: blr4362(hom)
            BRA: BRADO3572(hom)
            BBT: BBta_3996(hom)
            RPA: RPA2504(HDH)
            RPB: RPB_2966
            RPC: RPC_2816
            RPD: RPD_2495
            RPE: RPE_2937
            RPT: Rpal_2783
            RPX: Rpdx1_3012
            NWI: Nwi_1647
            NHA: Nham_2309
            OCA: OCAR_6016
            BHE: BH10030(metM)
            BTR: Btr_1379(hom)
            BGR: Bgr_12260(hom)
            XAU: Xaut_3521
            AZC: AZC_1848
            SNO: Snov_1365
            MEX: Mext_1967
            MEA: Mex_1p1941(hom)
            MDI: METDI2730(hom)
            MRD: Mrad2831_2919
            MET: M446_2698
            MPO: Mpop_1922
            MCH: Mchl_2243
            MNO: Mnod_3264
            BID: Bind_1387
            MSL: Msil_2074
            HDN: Hden_1523
            RVA: Rvan_3670
            CCR: CC_1383
            CCS: CCNA_01447
            CAK: Caul_3015
            CSE: Cseg_1683
            PZU: PHZ_c1643(hom)
            SIL: SPO1734(hom)
            SIT: TM1040_2164
            RSP: RSP_0403
            RSH: Rsph17029_2057
            RSQ: Rsph17025_0834
            RSK: RSKD131_1734
            RCP: RCAP_rcc03061(hom)
            JAN: Jann_2998
            RDE: RD1_2538(hom)
            PDE: Pden_3678
            DSH: Dshi_2273
            KVU: EIO_2461
            MMR: Mmar10_1098 Mmar10_2618
            HNE: HNE_2310(hom)
            HBA: Hbal_1864
            ZMO: ZMO0483
            ZMN: Za10_0771
            NAR: Saro_0019
            SAL: Sala_0810
            SWI: Swit_4731
            SJP: SJA_C1-07280(thrA)
            ELI: ELI_13775
            GOX: GOX1517
            GBE: GbCGDNIH1_1434
            ACR: Acry_1298
            GDI: GDI_1033
            GDJ: Gdia_2504
            APT: APA01_21340
            RRU: Rru_A2410
            RCE: RC1_1305(hom)
            MAG: amb3728
            AZL: AZL_010930(thrA)
            PBR: PB2503_10209
            APB: SAR116_0486
            MGM: Mmc1_1756
            DIN: Selin_0814
            BSU: BSU32260(hom)
            BSS: BSUW23_15730(hom)
            BHA: BH1253 BH1737 BH3422(hom)
            BAN: BA_1968(hom-1) BA_2608 BA_5654(hom-2)
            BAR: GBAA_1968(hom-1) GBAA_2608 GBAA_5654(hom-2)
            BAT: BAS1825 BAS2433 BAS5256
            BAH: BAMEG_1987 BAMEG_2623(hom1) BAMEG_5698(hom2)
            BAI: BAA_2036(hom1) BAA_2671 BAA_5681(hom2)
            BAL: BACI_c19420(hom1) BACI_c25870(hom2) BACI_c53990(hom3)
            BCE: BC1964 BC2548 BC5404
            BCA: BCE_2051(hom) BCE_2626 BCE_5533(hom)
            BCZ: BCZK1782(hom) BCZK2354(hom) BCZK5102(hom)
            BCR: BCAH187_A2073(hom1) BCAH187_A2664 BCAH187_A5583(hom2)
            BCB: BCB4264_A1970(hom1) BCB4264_A2580 BCB4264_A5527(hom2)
            BCU: BCAH820_2002(hom1) BCAH820_2625 BCAH820_5499
            BCG: BCG9842_B2743 BCG9842_B3357(hom1) BCG9842_B5424(hom2)
            BCQ: BCQ_1957(hom) BCQ_2482(hom) BCQ_5246(hom)
            BCX: BCA_2030(hom1) BCA_2698 BCA_5556
            BCY: Bcer98_1496 Bcer98_3923
            BTK: BT9727_1799(hom) BT9727_2388(hom) BT9727_5085(hom)
            BTL: BALH_1741(hom) BALH_2348(hom) BALH_4905(hom)
            BTB: BMB171_C1752(hom1) BMB171_C2310 BMB171_C4998(hom2)
            BWE: BcerKBAB4_1833 BcerKBAB4_2526 BcerKBAB4_5197
            BLI: BL02137(hom)
            BLD: BLi03414(hom)
            BAY: RBAM_029370(hom)
            BAO: BAMF_3030(hom)
            BAE: BATR1942_13955
            BCL: ABC0023 ABC1578 ABC2942(hom)
            BPU: BPUM_2888(thrA)
            BPF: BpOF4_04890(hdhA) BpOF4_11785(hom) BpOF4_15865(hom)
            BMQ: BMQ_4976(hom)
            BMD: BMD_4962(hom)
            BSE: Bsel_3261
            BCO: Bcell_3357 Bcell_4171
            OIH: OB0466
            GKA: GK2964
            GTN: GTNG_2268 GTNG_2914
            GWC: GWCH70_2896
            GYM: GYMC10_1550
            GYC: GYMC61_3041
            GYA: GYMC52_3064
            GCT: GC56T3_0541
            GMC: GY4MC1_0529
            AFL: Aflv_2414(hom)
            SAU: SA1164(dhoM)
            SAV: SAV1328(dhoM)
            SAW: SAHV_1317(dhoM)
            SAH: SaurJH1_1416
            SAJ: SaurJH9_1389
            SAM: MW1215(dhoM)
            SAS: SAS1268
            SAR: SAR1338
            SAC: SACOL1362(hom)
            SAX: USA300HOU_1273(thrA)
            SAA: SAUSA300_1226
            SAO: SAOUHSC_01320
            SAE: NWMN_1240(metL)
            SAD: SAAV_1308
            SAB: SAB1186
            SEP: SE1009
            SER: SERP0897(hom)
            SHA: SH1579(dhoM)
            SSP: SSP1438
            SCA: Sca_0970(hom)
            SLG: SLGD_01570
            SSD: SPSINT_1059
            LMO: lmo2547(hom)
            LMF: LMOf2365_2520(hom)
            LMH: LMHCC_0050
            LMC: Lm4b_02516(hom)
            LMN: LM5578_2742(hom)
            LMY: LM5923_2691(hom)
            LIN: lin2691
            LWE: lwe2496(hom)
            LSG: lse_2448(hom)
            LSP: Bsph_0843
            MCL: MCCL_0985
            BBE: BBR47_18540(hom) BBR47_30190 BBR47_30780
            PJD: Pjdr2_4407
            PPY: PPE_03652
            PPM: PPSC2_c4133
            AAC: Aaci_2233
            BTS: Btus_0940
            LLA: L0090(hom)
            LLK: LLKF_1185(hom)
            LLC: LACR_1280
            LLM: llmg_1332(hom)
            SPN: SP_1361
            SPD: SPD_1195(hom)
            SPR: spr1219(hom)
            SPW: SPCG_1350(hom)
            SPX: SPG_1302(metM)
            SNE: SPN23F_13270(hom)
            SPV: SPH_1493
            SNM: SP70585_1400
            SJJ: SPJ_1261
            SPP: SPP_1381
            SNC: HMPREF0837_11188(hom)
            SNB: SP670_0935
            SNP: SPAP_1391
            SAG: SAG1120(hom)
            SAN: gbs1187
            SAK: SAK_1205(hom)
            SMU: SMU.965
            SMC: SmuNN2025_1056
            STC: str0469(hom)
            STL: stu0469(hom)
            STE: STER_0506
            SSA: SSA_1043(hom)
            SSU: SSU05_0801
            SSV: SSU98_0801
            SSB: SSUBM407_1086(hom)
            SSI: SSU0747(hom)
            SSS: SSUSC84_0712(hom)
            SGO: SGO_0801(hom)
            SEQ: SZO_08990
            SEZ: Sez_1067(hom)
            SEU: SEQ_1121
            SUB: SUB0810(hom)
            SDS: SDEG_0858
            SGA: GALLO_1241(hom)
            SMB: smi_0773(thrA)
            LPL: lp_0571(hom2) lp_2535(hom1)
            LPJ: JDM1_0468(hom2) JDM1_2041(hom1)
            LPS: LPST_C0477(hom2) LPST_C2089(hom1)
            LAC: LBA1212
            LSL: LSL_1519(thrA)
            LDB: Ldb1350
            LBU: LBUL_1259
            LDE: LDBND_1293
            LCA: LSEI_2151
            LCB: LCABL_23330(thrA)
            LCZ: LCAZH_2111
            LGA: LGAS_1075
            LFE: LAF_1145
            LRH: LGG_02155(thrA)
            LRL: LC705_02162(thrA)
            LCR: LCRIS_01232(hom)
            EFA: EF2422(hom)
            OOE: OEOE_1546
            LME: LEUM_0786
            LCI: LCK_00723(hom)
            LKI: LKI_09900
            LGS: LEGAS_1092(thrA)
            CAC: CA_C0998
            CTC: CTC00886 CTC02355
            CNO: NT01CX_0896
            CTH: Cthe_0290 Cthe_1376
            CDF: CD1166(hom1) CD1580(hom2)
            CDC: CD196_1025(hom1) CD196_1502(hom2)
            CDL: CDR20291_1003(hom1) CDR20291_1477(hom2)
            CBO: CBO1641(hom) CBO1875(hom)
            CBA: CLB_1658(hom-1) CLB_1812(hom-2)
            CBH: CLC_1667(hom-1) CLC_1819(hom-2)
            CBY: CLM_1882(hom) CLM_2091(hom)
            CBL: CLK_1105(hom) CLK_1265(hom)
            CBK: CLL_A1041(hom)
            CBB: CLD_2762(hom) CLD_2914(hom)
            CBI: CLJ_B1750(hom_1) CLJ_B2061(hom_2)
            CBT: CLH_0975(hom)
            CBF: CLI_1718(hom-1) CLI_1939(hom-2)
            CBE: Cbei_1551
            CKL: CKL_0859(hom1) CKL_1105(hom2)
            CKR: CKR_0772 CKR_1006
            CPY: Cphy_3603
            CCE: Ccel_1452
            CLJ: CLJU_c07150(hom1) CLJU_c10090(hom2)
            CSH: Closa_0617
            CCB: Clocel_2875
            CST: CLOST_0901
            AMT: Amet_0566
            AOE: Clos_2186
            STH: STH2739
            SWO: Swol_1319
            SLP: Slip_1468
            VPR: Vpar_0899
            AFN: Acfer_1233
            DSY: DSY1363
            DHD: Dhaf_2479
            DRM: Dred_1165
            DAE: Dtox_2114
            PTH: PTH_1601(thrA)
            DAU: Daud_1073
            TJR: TherJR_2114
            HMO: HM1_1936(thrA)
            FMA: FMG_0319
            EEL: EUBELI_00370 EUBELI_01437
            ERE: EUBREC_0724
            ELM: ELI_3154
            BPB: bpr_I2441
            EHA: Ethha_2767
            RAL: Rumal_3157
            TMR: Tmar_1285
            TTE: TTE2152(thrA) TTE2620(thrA2)
            TEX: Teth514_0975 Teth514_2311
            TPD: Teth39_0140 Teth39_0500
            TIT: Thit_1836 Thit_2272
            TMT: Tmath_1812 Tmath_2179
            TBO: Thebr_0146 Thebr_0513
            CHY: CHY_1912(hom)
            MTA: Moth_1307
            ADG: Adeg_0882
            CSC: Csac_0993
            ATE: Athe_1959
            COB: COB47_1769
            CHD: Calhy_0816
            COW: Calow_1683
            CKI: Calkr_0744
            CKN: Calkro_0733
            TTM: Tthe_2599
            NTH: Nther_0669
            HOR: Hore_08020
            HAS: Halsa_1190
            AAR: Acear_1069
            MTU: Rv1294(thrA)
            MTC: MT1333(thrA)
            MRA: MRA_1302(thrA)
            MTF: TBFG_11321
            MTB: TBMG_02686(TBMG_02686.1)
            MBO: Mb1326(thrA)
            MBB: BCG_1354(thrA)
            MBT: JTY_1329(thrA)
            MLE: ML1129(hom)
            MLB: MLBr_01129(hom)
            MPA: MAP2468c(thrA)
            MAV: MAV_1509
            MSM: MSMEG_4957
            MUL: MUL_3970(thrA)
            MVA: Mvan_4348
            MGI: Mflv_2298
            MAB: MAB_1435
            MMC: Mmcs_3896
            MKM: Mkms_3970
            MJL: Mjls_3882
            MSP: Mspyr1_17300
            MMI: MMAR_4103(thrA)
            CGL: NCgl1136(cgl1183)
            CGB: cg1337(hom)
            CGT: cgR_1262
            CEF: CE1289
            CDI: DIP1036(thrA)
            CJK: jk1352(hom)
            CUR: cur_0694
            CAR: cauri_1049(hom)
            CKP: ckrop_1290
            CPU: cpfrc_00833(hom)
            NFA: nfa10490(thrA)
            RHA: RHA1_ro01488(thrA)
            RER: RER_39220(hom)
            ROP: ROP_11980
            REQ: REQ_17440(thrA)
            GBR: Gbro_1901
            TPR: Tpau_1230
            SRT: Srot_0682
            SCO: SCO0420(SCF51.19c) SCO5354(SCBAC5H2.23)
            SMA: SAV_2918(thrA)
            SGR: SGR_2182
            SCB: SCAB_28961(thrA) SCAB_3841
            TWH: TWT439(thrA)
            TWS: TW329(hom)
            LXX: Lxx06870(thrA)
            CMI: CMM_1153(thrA)
            CMS: CMS_1477
            ART: Arth_2623 Arth_3560
            AAU: AAur_2612(thrA)
            ACH: Achl_2356
            AAI: AARI_12590(thrA)
            RSA: RSal33209_1429
            KRH: KRH_09640(hom)
            MLU: Mlut_08020
            RMU: RMDY18_13080
            RDN: HMPREF0733_11706(thrA)
            BCV: Bcav_1281
            BFA: Bfae_19340
            JDE: Jden_1790
            KSE: Ksed_14810
            XCE: Xcel_2465
            SKE: Sked_09870
            CFL: Cfla_1055
            ICA: Intca_2453
            PAC: PPA1258
            PAK: HMPREF0675_4321
            PFR: PFREUD_10320(thrA)
            NCA: Noca_1744
            KFL: Kfla_5066
            TFU: Tfu_2424
            NDA: Ndas_0318
            TCU: Tcur_3939
            SRO: Sros_1638
            FRA: Francci3_3725
            FRE: Franean1_1005
            FRI: FraEuI1c_0923
            FAL: FRAAL5951(hom)
            ACE: Acel_0630
            NML: Namu_2095
            GOB: Gobs_4153
            KRA: Krad_1252
            SEN: SACE_2236 SACE_6298(thrA)
            SVI: Svir_29960
            TBI: Tbis_0879
            AMD: AMED_7795(thrA)
            AMI: Amir_6156
            STP: Strop_3651
            SAQ: Sare_4033
            MAU: Micau_5158
            MIL: ML5_3152
            CAI: Caci_1199
            SNA: Snas_5546
            MCU: HMPREF0573_10380(hom)
            BLO: BL1274(thrA)
            BLJ: BLD_1607(thrA)
            BLN: Blon_2316
            BLL: BLJ_1842
            BLB: BBMN68_1532(thrA)
            BAD: BAD_1416(thrA)
            BLA: BLA_0616(thrA)
            BLC: Balac_1415
            BLT: Balat_1415
            BDE: BDP_1929(thrA)
            BBI: BBIF_0263(thrA)
            BBP: BBPR_0241(thrA)
            GVA: HMPREF0424_1231
            GVG: HMPREF0421_20315(thrA)
            RXY: Rxyl_1091
            CWO: Cwoe_1792
            AFO: Afer_1813
            CCU: Ccur_01680
            SHI: Shel_26330
            APV: Apar_0540
            ELE: Elen_0280
            OLS: Olsu_0762
            SSM: Spirs_2770
            LIL: LA_3638(thrA)
            LIC: LIC10571(hom)
            LBJ: LBJ_2852(thrA)
            LBL: LBL_0219(thrA)
            LBI: LEPBI_I0064(hom)
            LBF: LBF_0064(thrA)
            BHY: BHWA1_00358
            BRM: Bmur_0171
            BPO: BP951000_0061
            ABA: Acid345_1481 Acid345_4165
            ACA: ACP_0317
            TSA: AciPR4_3474
            SUS: Acid_0526 Acid_7030
            BTH: BT_2403(thrA)
            BFR: BF0608(thrA)
            BFS: BF0558(thrA)
            BVU: BVU_2050(thrA)
            BHL: Bache_1164
            PDI: BDI_0261(thrA)
            PPN: Palpr_0165
            APS: CFPG_657(thrA)
            PRU: PRU_1016(thrA)
            PMZ: HMPREF0659_A6944
            SRU: SRU_0482 SRU_0691(thrA)
            SRM: SRM_00562(thrA) SRM_00867(metL)
            RMR: Rmar_2222
            CHU: CHU_0073(thrA)
            DFE: Dfer_3152(thrA)
            SLI: Slin_4514
            LBY: Lbys_0631
            MTT: Ftrac_1141 Ftrac_2862
            CPI: Cpin_1962 Cpin_5429
            PHE: Phep_1873 Phep_3804(thrA)
            GFO: GFO_0318(hom) GFO_1970(thrA)
            FJO: Fjoh_1492 Fjoh_1494 Fjoh_2575(thrA)
            FPS: FP0255
            COC: Coch_0411
            RBI: RB2501_12949(thrA)
            ZPR: ZPR_2267
            CAT: CA2559_07425
            RAN: Riean_1577
            FBC: FB2170_15118
            CAO: Celal_2921
            SMG: SMGWSS_141(thrA)
            SMS: SMDSEM_149(thrA)
            SMH: DMIN_01370
            SUM: SMCARI_156(thrA)
            BBL: BLBBGE_501(thrA)
            BPI: BPLAN_138(thrA)
            FSU: Fisuc_2253
            LBA: Lebu_0845
            STR: Sterm_3015
            IPO: Ilyop_0666
            OTE: Oter_2235
            CAA: Caka_2602
            MIN: Minf_0747(thrA)
            AMU: Amuc_1964
            GAU: GAU_1367
            RBA: RB8510(hom)
            PSL: Psta_4305
            PLM: Plim_2809
            IPA: Isop_0683
            EMI: Emin_0284 Emin_0860
            RSD: TGRD_569
            TAI: Taci_0506
            ACO: Amico_0287 Amico_0491 Amico_0519 Amico_1642
            SYN: sll0455(thrA)
            SYW: SYNW0711(thrA)
            SYC: syc2003_c(thrA)
            SYF: Synpcc7942_2090
            SYD: Syncc9605_1957
            SYE: Syncc9902_0704
            SYG: sync_0941(hom)
            SYR: SynRCC307_0723(thrA)
            SYX: SynWH7803_1606(thrA)
            SYP: SYNPCC7002_A2131(hom)
            CYA: CYA_1100(hom)
            CYB: CYB_1425(hom)
            TEL: tll0277(thrA)
            MAR: MAE_45060(thrA)
            CYT: cce_2359(thrA)
            CYP: PCC8801_0799
            CYC: PCC7424_0286
            CYN: Cyan7425_4262
            CYH: Cyan8802_0827
            CYJ: Cyan7822_1985
            CYU: UCYN_03990
            GVI: gvip559(thrA)
            ANA: all4120(thrA)
            NPU: Npun_R2750
            AVA: Ava_0783
            NAZ: Aazo_4841
            PMA: Pro1150(thrA)
            PMM: PMM1051(thrA)
            PMT: PMT1143(thrA)
            PMN: PMN2A_0702
            PMI: PMT9312_1062
            PMB: A9601_11561(thrA)
            PMC: P9515_11421(thrA)
            PMF: P9303_08881(thrA)
            PMG: P9301_11571(thrA)
            PMH: P9215_11861(thrA)
            PMJ: P9211_11401(thrA)
            PME: NATL1_15361(thrA)
            TER: Tery_4567
            AMR: AM1_2061(thrA)
            CTE: CT2030(thrA)
            CPC: Cpar_1907(thrA)
            CCH: Cag_0142(thrA)
            CPH: Cpha266_2542(thrA)
            CPB: Cphamn1_0299(thrA)
            CLI: Clim_2330(thrA)
            PVI: Cvib_1626(thrA)
            PLT: Plut_1983(thrA)
            PPH: Ppha_2703(thrA)
            PAA: Paes_0264(thrA)
            CTS: Ctha_1361(thrA)
            DET: DET1206(metM)
            DEH: cbdb_A1123(metM)
            DEB: DehaBAV1_1016
            DEV: DhcVS_989(metM)
            DEG: DehalGT_0947
            DLY: Dehly_0961
            RRS: RoseRS_1971 RoseRS_2987
            RCA: Rcas_1559 Rcas_2086
            CAU: Caur_1922 Caur_3338
            CAG: Cagg_1017 Cagg_2574
            CHL: Chy400_2076 Chy400_3600
            TRO: trd_0367
            STI: Sthe_1548
            ATM: ANT_27540(hom)
            DRA: DR_1278
            DGE: Dgeo_0610
            DDR: Deide_15930
            DMR: Deima_1460
            TRA: Trad_2552
            TTH: TTC0115
            TTJ: TTHA0489
            TSC: TSC_c19560
            MRB: Mrub_2400
            MSV: Mesil_1361
            OPR: Ocepr_1317
            AAE: aq_1812(thrA)
            HYA: HY04AAS1_1413
            HTH: HTH_0313(thrA)
            TAL: Thal_0606
            SUL: SYO3AOP1_0498
            SAF: SULAZ_0413
            PMX: PERMA_1054
            TAM: Theam_0190
            TMA: TM0547
            TPT: Tpet_0373
            TLE: Tlet_1364
            TRQ: TRQ2_0390
            TNA: CTN_0121
            TNP: Tnap_0327
            PMO: Pmob_1153
            DTH: DICTH_1252
            DTU: Dtur_1366
            TYE: THEYE_A1986
            NDE: NIDE4114(hom)
            TTR: Tter_0844
            DDF: DEFDS_1176(hom)
            DAP: Dacet_1419
            CNI: Calni_0867
            MJA: MJ_1602
            MFE: Mefer_0316
            MVU: Metvu_1166
            MFS: MFS40622_0463
            MIF: Metin_0011
            MMP: MMP1702(hom)
            MMQ: MmarC5_1704
            MMX: MmarC6_0969
            MMZ: MmarC7_0977
            MAE: Maeo_1209
            MVN: Mevan_1004
            MVO: Mvol_1260
            MAC: MA2572
            MBA: Mbar_A1898
            MMA: MM_2713
            MBU: Mbur_1087
            MMH: Mmah_0568
            MEV: Metev_0891
            MTP: Mthe_0845
            MHU: Mhun_2292
            MLA: Mlab_0481
            MEM: Memar_0971
            MPI: Mpet_1242
            MBN: Mboo_1354
            MPL: Mpal_1993
            MPD: MCP_1713
            MTH: MTH1232 MTH417
            MMG: MTBMA_c08120(thrA) MTBMA_c16200(hom)
            MST: Msp_0487
            MSI: Msm_0154
            MRU: mru_1140(hom)
            MFV: Mfer_0421
            MKA: MK1554(thrA)
            AFU: AF0935(hom)
            APO: Arcpr_0276
            FPL: Ferp_0062
            HAL: VNG2650G(hom)
            HSL: OE4722R(hom)
            HMA: rrnAC2408(hom)
            HWA: HQ3386A(hom)
            NPH: NP0302A(hom)
            HLA: Hlac_0155
            HUT: Huta_0812
            HMU: Hmuk_0498
            HTU: Htur_0818
            NMG: Nmag_2515
            HVO: HVO_0358(hom1) HVO_0601(hom2)
            HJE: HacjB3_15185
            HBO: Hbor_28120
            TAC: Ta1179
            TVO: TVN0385
            PTO: PTO1417
            PHO: PH1075
            PAB: PAB0610(hom)
            PFU: PF1104
            TKO: TK1627
            TON: TON_0036
            TGA: TGAM_2031(hom)
            TSI: TSIB_1477
            TBA: TERMP_00085
            RCI: LRC427(thrA)
            APE: APE_1144.1(hom)
            IAG: Igag_1758
            SSO: SSO0657(thrA)
            STO: ST1519
            SAI: Saci_1636(hdh)
            SIS: LS215_1587
            SIA: M1425_1479
            SIM: M1627_1594
            SID: M164_1476
            SIY: YG5714_1483
            SIN: YN1551_1353
            SII: LD85_1686
            MSE: Msed_2003
            PAI: PAE2868
            PIS: Pisl_0271
            PCL: Pcal_0379
            PAS: Pars_0949
            CMA: Cmaq_0731
            TNE: Tneu_1842
            VDI: Vdis_0607
            NMR: Nmar_0696
            CSY: CENSYa_0263
            KCR: Kcr_0008
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.3
            IUBMB Enzyme Nomenclature: 1.1.1.3
            ExPASy - ENZYME nomenclature database: 1.1.1.3
            BRENDA, the Enzyme Database: 1.1.1.3
            CAS: 9028-13-1
///
ENTRY       EC 1.1.1.4                  Enzyme
NAME        (R,R)-butanediol dehydrogenase;
            butyleneglycol dehydrogenase;
            D-butanediol dehydrogenase;
            D-(-)-butanediol dehydrogenase;
            butylene glycol dehydrogenase;
            diacetyl (acetoin) reductase;
            D-aminopropanol dehydrogenase;
            D-aminopropanol dehydrogenase;
            1-amino-2-propanol dehydrogenase;
            2,3-butanediol dehydrogenase;
            D-1-amino-2-propanol dehydrogenase;
            (R)-diacetyl reductase;
            (R)-2,3-butanediol dehydrogenase;
            D-1-amino-2-propanol:NAD+ oxidoreductase;
            1-amino-2-propanol oxidoreductase;
            aminopropanol oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R,R)-butane-2,3-diol:NAD+ oxidoreductase
REACTION    (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+ [RN:R02946]
ALL_REAC    R02946
SUBSTRATE   (R,R)-butane-2,3-diol [CPD:C03044];
            NAD+ [CPD:C00003]
PRODUCT     (R)-acetoin [CPD:C00810];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also converts diacetyl into acetoin with NADH as reductant.
REFERENCE   1  [PMID:13211662]
  AUTHORS   STRECKER HJ, HARARY I.
  TITLE     Bacterial butylene glycol dehydrogenase and diacetyl reductase.
  JOURNAL   J. Biol. Chem. 211 (1954) 263-70.
  ORGANISM  Klebsiella pneumoniae [GN:kpn], Staphylococcus aureus
REFERENCE   2  [PMID:13837186]
  AUTHORS   TAYLOR MB, JUNI E.
  TITLE     Stereoisomeric specificities of 2,3-butanediol dehydrogenases.
  JOURNAL   Biochim. Biophys. Acta. 39 (1960) 448-57.
  ORGANISM  Bacillus subtilis [GN:bsu], Bacillus polymyxa
PATHWAY     ec00650  Butanoate metabolism
ORTHOLOGY   K00004  (R,R)-butanediol dehydrogenase / diacetyl reductase
            K03366  (R,R)-butanediol dehydrogenase / diacetyl reductase
GENES       SCE: YAL060W(BDH1) YAL061W(BDH2)
            KLA: KLLA0F00506g KLLA0F00528g
            LTH: KLTH0D00616g
            VPO: Kpol_1049p18
            CGR: CAGL0D00198g
            PIC: PICST_89701(SOR1)
            PGU: PGUG_04554
            CAL: CaO19.769(BDH1)
            CTP: CTRG_04478
            CDU: CD36_04500
            ECY: ECSE_P3-0048
            ECA: ECA0310(budC)
            PCT: PC1_0296
            PWA: Pecwa_0303
            EBI: EbC_pEb17201130
            ENT: Ent638_2028
            ENC: ECL_03125
            ESA: ESA_00862
            CTU: Ctu_29850(budC)
            KPN: KPN_02061
            KPE: KPK_2269(budC)
            KPU: KP1_3140
            KVA: Kvar_2212
            PMR: PMI2092(budC)
            DDA: Dd703_0990
            DDC: Dd586_3192
            DDD: Dda3937_03162
            DZE: Dd1591_0974
            PAM: PANA_3970(budC)
            PVA: Pvag_pPag10121(butA)
            PRW: PsycPRwf_2380
            ACI: ACIAD1021 ACIAD1022(budC)
            ACD: AOLE_10240
            ACB: A1S_1704 A1S_1705
            ABM: ABSDF1933(budC) ABSDF1934
            ABY: ABAYE1943 ABAYE1944(budC)
            ABC: ACICU_01739 ACICU_01740
            ABN: AB57_1932 AB57_1933
            ABB: ABBFA_001791(gutB) ABBFA_001792
            MCT: MCR_1660
            SFR: Sfri_0232
            ILO: IL0792
            PIN: Ping_2541
            NOC: Noc_0093
            NWA: Nwat_2599
            MMW: Mmwyl1_2069
            NMA: NMA0808
            NME: NMB0604
            NMC: NMC0547
            NMN: NMCC_0550
            NMI: NMO_0489(tdh)
            NGO: NGO0186
            NGK: NGK_0240
            BUR: Bcep18194_B2443
            DAC: Daci_2959
            PCA: Pcar_0903 Pcar_2068
            PPD: Ppro_3110
            SME: SMc01455(dld)
            SMD: Smed_3132
            ATU: Atu2053
            ARA: Arad_8177
            RET: RHE_CH02403(ypch00793)
            REC: RHECIAT_CH0002498
            RLE: RL2725
            RLT: Rleg2_2038
            RLG: Rleg_2261
            XAU: Xaut_4042
            AZC: AZC_1906
            BID: Bind_0358
            RSH: Rsph17029_3545
            DSH: Dshi_4158
            HBA: Hbal_1494
            GOX: GOX2036
            GDI: GDI_2623(budA)
            GDJ: Gdia_0838
            AZL: AZL_009050
            BSS: BSUW23_09960
            BCE: BC0668
            BCA: BCE_3248(gutB)
            BLI: BL01177
            BLD: BLi02066
            BCL: ABC0681
            SAU: SA0122(butA)
            SAV: SAV0126(butA)
            SAW: SAHV_0125(butA)
            SAH: SaurJH1_0117
            SAJ: SaurJH9_0113
            SAM: MW0100(butA)
            SAS: SAS0101
            SAR: SAR0129
            SAC: SACOL0111
            SAX: USA300HOU_0138
            SAA: SAUSA300_0129
            SAO: SAOUHSC_00086
            SAE: NWMN_0071
            SAD: SAAV_0094
            SAB: SAB0066
            SEP: SE0197 SE2225
            SER: SERP2257 SERP2379
            SCA: Sca_0065
            SLG: SLGD_00178 SLGD_01196
            LLA: L117145(butB) L118271(butA)
            LLK: LLKF_0924(butB) LLKF_0925(butA)
            LLC: LACR_0363 LACR_0974
            LLM: llmg_0339(dar) llmg_1641(butA) llmg_1642(butB)
            SPZ: M5005_Spy_0534 M5005_Spy_0535
            SPM: spyM18_0709
            SPG: SpyM3_0458
            SPS: SPs1397
            SPH: MGAS10270_Spy0529
            SPI: MGAS10750_Spy0553
            SPJ: MGAS2096_Spy0546
            SPK: MGAS9429_Spy0525
            SPF: SpyM51329
            SPA: M6_Spy0555
            SPB: M28_Spy0513
            SOZ: Spy49_0540
            SAG: SAG0523
            SAN: gbs0569
            SAK: SAK_0674
            SMU: SMU.1322(budC)
            SMC: SmuNN2025_0740(budC)
            SGO: SGO_1096(butA)
            SGA: GALLO_0485
            SMB: smi_0567
            LSA: LSA0292(budC)
            LBR: LVIS_0187 LVIS_1802
            LRE: Lreu_1449
            LRF: LAR_1360
            LFE: LAF_1480
            PPE: PEPE_0286
            OOE: OEOE_0077 OEOE_0693
            LME: LEUM_0117 LEUM_0145 LEUM_1148
            LCI: LCK_00104 LCK_00504
            LKI: LKI_00845 LKI_02490 LKI_04070
            LGS: LEGAS_0209(butA1) LEGAS_1299(butA2)
            CNO: NT01CX_0344
            MSM: MSMEG_5020
            MVA: Mvan_0789
            MGI: Mflv_0124
            MMC: Mmcs_0625
            MKM: Mkms_0638
            MJL: Mjls_0618
            MSP: Mspyr1_06590
            CGL: NCgl2582(cgl2674)
            CGB: cg2958(butA)
            CGT: cgR_2577
            CDI: DIP2135
            CKP: ckrop_1425
            NFA: nfa30760
            RHA: RHA1_ro01633 RHA1_ro05279
            RER: RER_06590 RER_40280
            ROP: ROP_13310 ROP_53210
            GBR: Gbro_3625
            SCO: SCO0256(SCF20.02)
            ART: Arth_0880
            KRH: KRH_22550
            MLU: Mlut_07590
            RMU: RMDY18_10670
            JDE: Jden_0784
            NML: Namu_1091 Namu_1092
            SEN: SACE_3985
            SVI: Svir_32140
            BLA: BLA_1253(butA)
            BLC: Balac_0727
            BLT: Balat_0727
            GAU: GAU_0247
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.4
            IUBMB Enzyme Nomenclature: 1.1.1.4
            ExPASy - ENZYME nomenclature database: 1.1.1.4
            BRENDA, the Enzyme Database: 1.1.1.4
            CAS: 37250-09-2
///
ENTRY       EC 1.1.1.5        Obsolete  Enzyme
NAME        Transferred to 1.1.1.303 and 1.1.1.304
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
COMMENT     Transferred entry: acetoin dehydrogenase. Now EC 1.1.1.303, diacetyl
            reductase [(R)-acetoin forming] and EC 1.1.1.304, diacetyl reductase
            [(S)-acetoin forming] (EC 1.1.1.5 created 1961, modified 1976,
            deleted 2010)
///
ENTRY       EC 1.1.1.6                  Enzyme
NAME        glycerol dehydrogenase;
            glycerin dehydrogenase;
            NAD+-linked glycerol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     glycerol:NAD+ 2-oxidoreductase
REACTION    glycerol + NAD+ = glycerone + NADH + H+ [RN:R01034]
ALL_REAC    R01034
SUBSTRATE   glycerol [CPD:C00116];
            NAD+ [CPD:C00003]
PRODUCT     glycerone [CPD:C00184];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also acts on propane-1,2-diol.
REFERENCE   1  [PMID:13069498]
  AUTHORS   ASNIS RE, BRODIE AF.
  TITLE     A glycerol dehydrogenase from Escherichia coli.
  JOURNAL   J. Biol. Chem. 203 (1953) 153-9.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   2
  AUTHORS   Burton, R.M. and Kaplan, N.O.
  TITLE     A DPN specific glycerol dehydrogenase from Aerobacter aerogenes.
  JOURNAL   J. Am. Chem. Soc. 75 (1953) 1005-1007.
REFERENCE   3  [PMID:14417009]
  AUTHORS   LIN EC, MAGASANIK B.
  TITLE     The activation of glycerol dehydrogenase from Aerobacter aerogenes
            by monovalent cations.
  JOURNAL   J. Biol. Chem. 235 (1960) 1820-3.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
PATHWAY     ec00561  Glycerolipid metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K00005  glycerol dehydrogenase
GENES       SPO: SPAC13F5.03c(gld1)
            DDI: DDB_G0273503
            ECO: b3945(gldA)
            ECJ: JW5556(gldA)
            ECD: ECDH10B_4134(gldA)
            EBW: BWG_3614(gldA)
            ECE: Z5500(gldA)
            ECS: ECs4874(gldA)
            ECF: ECH74115_5406(gldA)
            ETW: ECSP_5015(gldA)
            EOJ: ECO26_5062(gldA)
            EOI: ECO111_4771(gldA)
            EOH: ECO103_4702(gldA)
            ECG: E2348C_4258(gldA)
            EOK: G2583_4757(gldA)
            ECC: c4904(gldA)
            ECP: ECP_4159(gldA)
            ECI: UTI89_C4536(gldA) UTI89_C5025(gldA)
            ECV: APECO1_2102(gldA) APECO1_2521(gldA)
            ECX: EcHS_A4180(gldA)
            ECW: EcE24377A_4485(gldA)
            ECM: EcSMS35_4393(gldA) EcSMS35_4859(gldA)
            ECY: ECSE_4239(gldA)
            ECR: ECIAI1_4154(gldA)
            ECQ: ECED1_4651(gldA)
            ECK: EC55989_4428(gldA)
            ECT: ECIAI39_3043(gldA)
            EUM: ECUMN_4477(gldA)
            ECZ: ECS88_4401(gldA)
            ECL: EcolC_4070(gldA)
            EBR: ECB_03831(gldA)
            EBD: ECBD_4078(gldA)
            EFE: EFER_3817(gldA)
            STY: STY3759(gldA)
            STT: t3509(gldA)
            STM: STM3529(gldA) STM4108(gldA)
            SPT: SPA3953(gldA)
            SEK: SSPA3679(gldA)
            SPQ: SPAB_04384(gldA) SPAB_05091(gldA)
            SEI: SPC_3598(gldA) SPC_4218(gldA)
            SEC: SC3460(gldA) SC4000(gldA)
            SEH: SeHA_C3838(gldA) SeHA_C4443(gldA)
            SEE: SNSL254_A3796(gldA) SNSL254_A4440(gldA)
            SEW: SeSA_A4325(gldA)
            SEA: SeAg_B3730(gldA) SeAg_B4356(gldA)
            SED: SeD_A3899(gldA) SeD_A4514(gldA)
            SEG: SG3308(gldA) SG3910(gldA)
            SET: SEN3354(gldA) SEN3902(gldA)
            SES: SARI_03549(gldA)
            YEN: YE0539(gldA)
            SSN: SSON_4119(gldA)
            SBO: SBO_3965(gldA)
            SBC: SbBS512_E4432(gldA)
            SDY: SDY_3780(gldA)
            ECA: ECA0846(gldA) ECA1523
            PCT: PC1_0734 PC1_1396
            PWA: Pecwa_1794
            EBI: EbC_14070 EbC_25200(gldA) EbC_39050
            PLU: plu4115(gldA)
            PAY: PAU_03738(gldA)
            ENT: Ent638_4031(gldA)
            ENC: ECL_05035
            ESC: Entcl_3458 Entcl_4294
            CTU: Ctu_05350(gldA)
            KPN: KPN_03494(dhaD) KPN_04241(gldA)
            KPE: KPK_0620 KPK_1827 KPK_5440(gldA)
            KPU: KP1_0104(gldA) KP1_4790(dhaD)
            KVA: Kvar_0606 Kvar_4980
            CKO: CKO_03049(gldA) CKO_04473
            CRO: ROD_37991(gldA)
            SPE: Spro_4273
            PMR: PMI2766(gldA) PMI3595(gldA)
            ETR: ETAE_0899(gldA)
            HDE: HDEF_2221(gldA)
            DDA: Dd703_1296 Dd703_2634
            DDC: Dd586_2938
            DDD: Dda3937_00057
            XBO: XBJ1_0544(gldA)
            XNE: XNC1_0651(gldA)
            PAM: PANA_0902(dhaD) PANA_2213(gldA)
            PVA: Pvag_1678(glda1) Pvag_1903(glda3) Pvag_pPag30203(gldA)
            PAO: Pat9b_1227 Pat9b_2319 Pat9b_5720
            VVY: VV0158(gldA)
            VPA: VP0363(gldA)
            VEX: VEA_001639
            PPW: PputW619_1690(gldA)
            AVN: Avin_39990
            SBL: Sbal_3356(gldA)
            SBM: Shew185_0985(gldA)
            SBN: Sbal195_1019(gldA)
            SBP: Sbal223_1007(gldA)
            SPC: Sputcn32_2945(gldA)
            SHW: Sputw3181_0997(gldA)
            AHA: AHA_2415(gldA) AHA_4005(gldA)
            ASA: ASA_2274(gldA) ASA_4048(gldA)
            TAU: Tola_1892(gldA)
            REU: Reut_B4570(gldA)
            BAC: BamMC406_4666
            BAV: BAV0489(gldA)
            AXY: AXYL_04860(gldA)
            VEI: Veis_1883(gldA)
            GLO: Glov_0712
            DAS: Daes_2321
            DAL: Dalk_0861(gldA)
            SFU: Sfum_0519
            DBR: Deba_0798
            SME: SMc02038(gldA)
            SMD: Smed_2460(gldA)
            AVI: Avi_6106(gldA)
            XAU: Xaut_0011 Xaut_1714
            MNO: Mnod_5662
            BLI: BL03089(gldA)
            BLD: BLi00828(gldA)
            BAY: RBAM_005990(gldA)
            BAO: BAMF_0498
            BAE: BATR1942_00370(gldA)
            BCL: ABC0560(gldA)
            BMQ: BMQ_1805(dhaD)
            OIH: OB0323(gldA)
            GMC: GY4MC1_2951
            SEP: SE0235(gldA)
            SER: SERP2346(gldA)
            ESI: Exig_1181(gldA)
            EAT: EAT1b_1857(gldA)
            PJD: Pjdr2_5051(gldA)
            PPY: PPE_02457 PPE_03074 PPE_03502
            PPM: PPSC2_c2809 PPSC2_c3418 PPSC2_c4011
            SPY: SPy_2047(gldA)
            SPZ: M5005_Spy_1741(gldA)
            SPM: spyM18_2108(gldA)
            SPG: SpyM3_1747(gldA)
            SPS: SPs1745(gldA)
            SPH: MGAS10270_Spy1810(gldA)
            SPI: MGAS10750_Spy1835(gldA)
            SPJ: MGAS2096_Spy1775(gldA)
            SPK: MGAS9429_Spy1750(gldA)
            SPF: SpyM51704(gldA)
            SPA: M6_Spy1741(gldA)
            SPB: M28_Spy1728(gldA)
            SOZ: Spy49_1695c(gldA)
            SPN: SP_0253(gldA)
            SPD: SPD_0237(gldA)
            SPR: spr0234(gldA)
            SPW: SPCG_0264(gldA)
            SPX: SPG_0240(gldA)
            SNE: SPN23F_02430(gldA)
            SPV: SPH_0371(gldA)
            SNM: SP70585_0315(gldA)
            SJJ: SPJ_0265(gldA)
            SPP: SPP_0305(gldA)
            SNT: SPT_0301(gldA)
            SNC: HMPREF0837_10569(gldA)
            SNB: SP670_0327
            SNP: SPAP_0302
            SAG: SAG0333(gldA) SAG2046
            SAN: gbs0321(gldA) gbs2002
            SAK: SAK_0403(gldA) SAK_1985
            SMU: SMU.1309c SMU.495(gldA)
            SMC: SmuNN2025_0750 SmuNN2025_1477(gldA)
            SSA: SSA_0287(gldA)
            SSU: SSU05_0717(gldA)
            SSV: SSU98_0716(gldA)
            SSB: SSUBM407_1161(gldA)
            SSI: SSU0670(gldA)
            SSS: SSUSC84_0636(gldA)
            SGO: SGO_1786(gldA)
            SEQ: SZO_18150(gldA)
            SEZ: Sez_1806(gldA)
            SEU: SEQ_2104(gldA)
            SDS: SDEG_0177(gldA)
            LSL: LSL_0028(gldA)
            LBR: LVIS_2165
            LRE: Lreu_1840
            LRF: LAR_1724
            LFE: LAF_0639
            EFA: EF1358(gldA)
            LCI: LCK_01397(gldA)
            LGS: LEGAS_0463(gldA)
            CPE: CPE0099(gldA)
            CPF: CPF_0094(gldA)
            CTC: CTC00596(gldA)
            CNO: NT01CX_0287(gldA) NT01CX_1239
            CBO: CBO0976(gldA) CBO1999(gldA)
            CBA: CLB_1016(gldA) CLB_1939(gldA)
            CBH: CLC_1030(gldA) CLC_1945(gldA)
            CBY: CLM_1132(gldA) CLM_2215(gldA)
            CBL: CLK_0424(gldA) CLK_1452(gldA)
            CBK: CLL_A0537(gldA) CLL_A1018 CLL_A1318
            CBB: CLD_2625(gldA) CLD_3589(gldA)
            CBI: CLJ_B1021(gldA) CLJ_B2203(gldA)
            CBT: CLH_0952 CLH_1267
            CBF: CLI_1062(gldA) CLI_2065(gldA)
            CBE: Cbei_2753(gldA)
            CLJ: CLJU_c26570
            CSH: Closa_0217
            CCB: Clocel_1990
            AOE: Clos_2306
            STH: STH1267(gldA)
            VPR: Vpar_1592
            AFN: Acfer_0865
            TJR: TherJR_0633
            ELM: ELI_1587 ELI_3470
            EHA: Ethha_1726 Ethha_1736
            MTA: Moth_0464
            TOC: Toce_0515
            TTM: Tthe_1821
            NTH: Nther_2706
            HAS: Halsa_2163
            AAR: Acear_0809 Acear_1494
            CDI: DIP1893
            CPU: cpfrc_01701
            TPR: Tpau_0498
            SKE: Sked_00260
            TFU: Tfu_2801(gldA)
            NDA: Ndas_2426
            FRE: Franean1_5962
            SHI: Shel_27210
            APV: Apar_0061 Apar_1052
            BHY: BHWA1_00133(gldA)
            BRM: Bmur_0051
            BPO: BP951000_2234(gldA)
            SRU: SRU_1614(gldA)
            SRM: SRM_01814(gldA)
            LBA: Lebu_0722
            STR: Sterm_1067
            IPO: Ilyop_1077
            SYN: slr1167(gldA)
            SYW: SYNW0939
            SYC: syc1815_d(gldA) syc2433_d(gldA)
            SYF: Synpcc7942_1653(gldA) Synpcc7942_2285
            SYD: Syncc9605_1626
            SYE: Syncc9902_1388
            SYG: sync_0649 sync_1026
            SYR: SynRCC307_0551(gldH) SynRCC307_0787(gldA)
            SYX: SynWH7803_1536(gldA)
            SYP: SYNPCC7002_A0605(gldA)
            TEL: tll2051(gldA)
            MAR: MAE_25770
            CYT: cce_1310(gldA)
            CYP: PCC8801_0088
            CYC: PCC7424_1321
            CYN: Cyan7425_3601
            CYH: Cyan8802_0085
            CYJ: Cyan7822_0246
            CYU: UCYN_03890
            GVI: gll1456
            ANA: alr2764
            NPU: Npun_R5095
            AVA: Ava_0016
            NAZ: Aazo_3356
            PMA: Pro1108(gldA)
            PMM: PMM1087(gldA)
            PMT: PMT1062(gldA)
            PMN: PMN2A_0661
            PMI: PMT9312_1098
            PMB: A9601_11931(gldA)
            PMC: P9515_11781(gldA)
            PMF: P9303_09901(gldA)
            PMG: P9301_11941(gldA)
            PMH: P9215_12231(gldA)
            PME: NATL1_14931(gldA)
            TER: Tery_1022
            AMR: AM1_3576(gldA)
            CPC: Cpar_1063
            PPH: Ppha_1046
            TRA: Trad_1223
            TMA: TM0423(gldA)
            TPT: Tpet_0498(gldA)
            TRQ: TRQ2_0522(gldA)
            TNA: CTN_0247(gldA)
            KOL: Kole_0505(gldA)
            MPL: Mpal_0772
            HAL: VNG6270G(gldA)
            HSL: OE5160F(gldA)
            HMA: rrnAC0175(egsA)
            HLA: Hlac_2109(gldA)
            NMG: Nmag_3814
            HJE: HacjB3_10515(gldA)
            IAG: Igag_0314
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.6
            IUBMB Enzyme Nomenclature: 1.1.1.6
            ExPASy - ENZYME nomenclature database: 1.1.1.6
            BRENDA, the Enzyme Database: 1.1.1.6
            CAS: 9028-14-2
///
ENTRY       EC 1.1.1.7                  Enzyme
NAME        propanediol-phosphate dehydrogenase;
            PDP dehydrogenase;
            1,2-propanediol-1-phosphate:NAD+ oxidoreductase;
            propanediol phosphate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     propane-1,2-diol-1-phosphate:NAD+ oxidoreductase
REACTION    propane-1,2-diol 1-phosphate + NAD+ = hydroxyacetone phosphate +
            NADH + H+ [RN:R04236]
ALL_REAC    R04236
SUBSTRATE   propane-1,2-diol 1-phosphate [CPD:C03894];
            NAD+ [CPD:C00003]
PRODUCT     hydroxyacetone phosphate [CPD:C03505];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13672935]
  AUTHORS   SELLINGER OZ, MILLER ON.
  TITLE     The metabolism of acetol phosphate. II. 1,2-Propanediol-1-phosphate
            dehydrogenase.
  JOURNAL   J. Biol. Chem. 234 (1959) 1641-6.
  ORGANISM  Oryctolagus cuniculus
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.7
            IUBMB Enzyme Nomenclature: 1.1.1.7
            ExPASy - ENZYME nomenclature database: 1.1.1.7
            BRENDA, the Enzyme Database: 1.1.1.7
            CAS: 9028-15-3
///
ENTRY       EC 1.1.1.8                  Enzyme
NAME        glycerol-3-phosphate dehydrogenase (NAD+);
            alpha-glycerol phosphate dehydrogenase (NAD+);
            alpha-glycerophosphate dehydrogenase (NAD+);
            glycerol 1-phosphate dehydrogenase;
            glycerol phosphate dehydrogenase (NAD+);
            glycerophosphate dehydrogenase (NAD+);
            hydroglycerophosphate dehydrogenase;
            L-alpha-glycerol phosphate dehydrogenase;
            L-alpha-glycerophosphate dehydrogenase;
            L-glycerol phosphate dehydrogenase;
            L-glycerophosphate dehydrogenase (ambiguous);
            NAD+-alpha-glycerophosphate dehydrogenase;
            NAD+-dependent glycerol phosphate dehydrogenase;
            NAD+-dependent glycerol-3-phosphate dehydrogenase;
            NAD+-L-glycerol-3-phosphate dehydrogenase;
            NAD+-linked glycerol 3-phosphate dehydrogenase;
            NADH-dihydroxyacetone phosphate reductase;
            glycerol-3-phosphate dehydrogenase (NAD+);
            L-glycerol-3-phosphate dehydrogenase (ambiguous)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     sn-glycerol-3-phosphate:NAD+ 2-oxidoreductase
REACTION    sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+
            [RN:R00842]
ALL_REAC    R00842
SUBSTRATE   sn-glycerol 3-phosphate [CPD:C00093];
            NAD+ [CPD:C00003]
PRODUCT     glycerone phosphate [CPD:C00111];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also acts on propane-1,2-diol phosphate and glycerone sulfate (but
            with a much lower affinity).
REFERENCE   1
  AUTHORS   Baranowski, T.
  TITLE     alpha-Glycerophosphate dehydrogenase.
  JOURNAL   In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
            ed., vol. 7, Academic Press, New York, 1963, p. 85-96.
REFERENCE   2  [PMID:4307630]
  AUTHORS   Brosemer RW, Kuhn RW.
  TITLE     Comparative structural properties of honeybee and rabbit
            alpha-glycerophosphate dehydrogenases.
  JOURNAL   Biochemistry. 8 (1969) 2095-105.
  ORGANISM  Apis mellifera [GN:ame], Oryctolagus cuniculus
REFERENCE   3  [PMID:4340553]
  AUTHORS   O'Brien SJ, MacIntyre RJ.
  TITLE     The  -glycerophosphate cycle in Drosophila melanogaster. I.
            Biochemical and developmental aspects.
  JOURNAL   Biochem. Genet. 7 (1972) 141-61.
  ORGANISM  Drosophila melanogaster [GN:dme]
REFERENCE   4  [PMID:4200180]
  AUTHORS   Warkentin DL, Fondy TP.
  TITLE     Isolation and characterization of cytoplasmic L-glycerol-3-phosphate
            dehydrogenase from rabbit-renal-adipose tissue and its comparison
            with the skeletal-muscle enzyme.
  JOURNAL   Eur. J. Biochem. 36 (1973) 97-109.
  ORGANISM  Oryctolagus cuniculus
REFERENCE   5  [PMID:1499720]
  AUTHORS   Albertyn J, van Tonder A, Prior BA.
  TITLE     Purification and characterization of glycerol-3-phosphate
            dehydrogenase of Saccharomyces cerevisiae.
  JOURNAL   FEBS. Lett. 308 (1992) 130-2.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
REFERENCE   6  [PMID:7671141]
  AUTHORS   Koekemoer TC, Litthauer D, Oelofsen W.
  TITLE     Isolation and characterization of adipose tissue
            glycerol-3-phosphate dehydrogenase.
  JOURNAL   Int. J. Biochem. Cell. Biol. 27 (1995) 625-32.
  ORGANISM  Homo sapiens [GN:hsa]
PATHWAY     ec00564  Glycerophospholipid metabolism
ORTHOLOGY   K00006  glycerol-3-phosphate dehydrogenase (NAD+)
GENES       HSA: 23171(GPD1L) 2819(GPD1)
            PTR: 741054(GPD1)
            PON: 100172201(GPD1) 100173675(GPD1L)
            MCC: 707723 713384(GPD1)
            MMU: 14555(Gpd1) 333433(Gpd1l)
            RNO: 363159(Gpd1l) 60666(Gpd1)
            CFA: 485626(GPD1L) 607942(GPD1)
            AML: 100470374 100473892
            BTA: 514456(GPD1L) 525042(GPD1)
            SSC: 100153250(GPD1) 100155892
            ECB: 100052204(GPD1) 100057124
            MDO: 100021123
            OAA: 100077586 100085954
            GGA: 420664(GPD1L) 424263(GPD1)
            TGU: 100219677(GPD1L) 100219837 100225600
            XLA: 379962(gpd1l) 399227(gpd1) 444456
            XTR: 394623(gpd1l) 448519(gpd1)
            DRE: 325181(gpd1b) 406615(gpd1) 449663(gpd1l) 550404(gpd1a)
            BFO: BRAFLDRAFT_226348
            CIN: 100181104
            DME: Dmel_CG3215 Dmel_CG9042(Gpdh)
            DPO: Dpse_GA16715
            DAN: Dana_GF13315 Dana_GF15589(Dana_Gpdh)
            DER: Dere_GG20063 Dere_GG25104(Dere_Gpdh)
            DPE: Dper_GL11294 Dper_GL19044(Dper_Gpdh)
            DSE: Dsec_GM15578
            DSI: Dsim_GD23370(Dsim_Gpdh) Dsim_GD25078
            DWI: Dwil_GK14706(Dwil_Gpdh) Dwil_GK19593
            DYA: Dyak_GE11600 Dyak_GE25734(Dyak_Gpdh)
            DGR: Dgri_GH11012 Dgri_GH23061
            DMO: Dmoj_GI17532 Dmoj_GI21131
            DVI: Dvir_GJ15413(Dvir_Gpdh) Dvir_GJ20981
            AGA: AgaP_AGAP007593
            AAG: AaeL_AAEL001593
            CQU: CpipJ_CPIJ000232
            AME: 726445(Gpdh)
            NVI: 100123685(NV14099) 100123687(NV14101)
            TCA: 663884
            API: 100160658
            PHU: Phum_PHUM174010
            ISC: IscW_ISCW005254
            CEL: F47G4.3(gpdh-1) K11H3.1(gpdh-2)
            CBR: CBG09958(Cbr-gpdh-2) CBG18871(Cbr-gpdh-1)
            BMY: Bm1_45570
            SMM: Smp_030500.1
            NVE: NEMVE_v1g156868 NEMVE_v1g211642
            HMG: 100200028
            TAD: TRIADDRAFT_38307
            ATH: AT5G40610
            POP: POPTR_908191
            RCU: RCOM_0531780
            VVI: 100261224
            SBI: SORBI_03g047310
            ZMA: 100284124
            PPP: PHYPADRAFT_186920
            CRE: CHLREDRAFT_96789
            VCN: VOLCADRAFT_57957
            CME: CMD113C
            SCE: YDL022W(GPD1) YOL059W(GPD2)
            AGO: AGOS_ADR311C
            KLA: KLLA0C04004g
            LTH: KLTH0F06622g
            PPA: PAS_chr2-2_0111
            VPO: Kpol_1037p2 Kpol_1045p48
            ZRO: ZYRO0A05390g
            CGR: CAGL0C05137g CAGL0K01683g
            DHA: DEHA2F09372g
            PIC: PICST_83071(GPD2) PICST_90446(GPD1)
            PGU: PGUG_01519 PGUG_05498
            LEL: LELG_02389 LELG_04817
            CAL: CaO19.1756(GPD1) CaO19.691(GPD2)
            CTP: CTRG_02011 CTRG_02898
            CDU: CD36_24300(GPD1) CD36_62130
            YLI: YALI0B02948g
            CLU: CLUG_03347 CLUG_05143
            NCR: NCU00742
            PAN: PODANSg09885
            MGR: MGG_00067(MG00067.4)
            FGR: FG05023.1
            SSL: SS1G_12794
            BFU: BC1G_05277
            ANI: AN0351.2 AN6792.2
            AFM: AFUA_1G02150 AFUA_2G08250
            NFI: NFIA_022500 NFIA_083910
            AOR: AO090005000883 AO090011000879
            ANG: An01g06110 An15g07390
            AFV: AFLA_046760 AFLA_081330
            ACT: ACLA_032280 ACLA_080090
            PCS: Pc20g06370 Pc22g22110
            CIM: CIMG_09984
            CPW: CPC735_011590
            URE: UREG_06029
            PNO: SNOG_03768
            TML: GSTUM_00004115001
            SPO: SPAC23D3.04c(gpd2) SPBC215.05(gpd1)
            CNE: CNA01100 CNC02480
            CNB: CNBA1070 CNBC4750
            MPR: MPER_10941
            SCM: SCHCODRAFT_54510
            UMA: UM00555.1
            MGL: MGL_2451
            ECU: ECU05_0270
            PFA: PF11_0157 PFL0780w
            PFD: PFDG_02150
            PFH: PFHG_03289 PFHG_04100
            PYO: PY00789 PY05585
            PCB: PC000289.03.0
            PBE: PB000629.01.0 PB001193.02.0
            PKN: PKH_091190 PKH_143330
            PVX: PVX_091380 PVX_123490
            TAN: TA21330
            TPV: TP01_0302
            BBO: BBOV_IV004480(23.m06005)
            CPV: cgd2_210
            CHO: Chro.20028
            TGO: TGME49_107570
            TBR: Tb927.8.3530
            LMA: LmjF10.0510(GPD)
            LIF: LinJ10.0850
            LBZ: LbrM10_V2.0640
            TVA: TVAG_230610 TVAG_382880
            PTI: PHATR_36821
            TPS: THAPSDRAFT_260786
            PIF: PITG_04065
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.8
            IUBMB Enzyme Nomenclature: 1.1.1.8
            ExPASy - ENZYME nomenclature database: 1.1.1.8
            BRENDA, the Enzyme Database: 1.1.1.8
            CAS: 9075-65-4
///
ENTRY       EC 1.1.1.9                  Enzyme
NAME        D-xylulose reductase;
            NAD+-dependent xylitol dehydrogenase;
            xylitol dehydrogenase;
            erythritol dehydrogenase;
            2,3-cis-polyol(DPN) dehydrogenase (C3-5);
            pentitol-DPN dehydrogenase;
            xylitol-2-dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)
REACTION    xylitol + NAD+ = D-xylulose + NADH + H+ [RN:R01896]
ALL_REAC    R01896
SUBSTRATE   xylitol [CPD:C00379];
            NAD+ [CPD:C00003]
PRODUCT     D-xylulose [CPD:C00310];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also acts as an L-erythrulose reductase.
REFERENCE   1  [PMID:13692998]
  AUTHORS   CHIANG C, KNIGHT SG.
  TITLE     A new pathway of pentose metabolism.
  JOURNAL   Biochem. Biophys. Res. Commun. 3 (1960) 554-9.
  ORGANISM  Penicillium chrysogenum [GN:pcs]
REFERENCE   2  [PMID:13654257]
  AUTHORS   HICKMAN J, ASHWELL G.
  TITLE     A sensitive and stereospecific enzymatic assay for xylulose.
  JOURNAL   J. Biol. Chem. 234 (1959) 758-61.
  ORGANISM  Cavia porcellus
REFERENCE   3  [PMID:13789254]
  AUTHORS   JAKOBY WB, FREDERICKS J.
  TITLE     Erythritol dehydrogenase from Aerobacter aerogenes.
  JOURNAL   Biochim. Biophys. Acta. 48 (1961) 26-32.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec01100  Metabolic pathways
ORTHOLOGY   K05351  D-xylulose reductase
GENES       SCE: YLR070C(XYL2)
            DHA: DEHA2A13992g
            PIC: PICST_86924(XYL2)
            CAL: CaO19.7676(XYL2)
            CTP: CTRG_05796
            CDU: CD36_35570(XYL2)
            CLU: CLUG_02658
            ANI: AN9064.2
            AFM: AFUA_7G02550
            NFI: NFIA_115270
            AOR: AO090038000631
            ANG: An12g00030
            ACT: ACLA_065000
            PCS: Pc21g11540
            ETA: ETA_16670
            PLU: plu1960
            PAY: PAU_02204(ydjJ)
            SGL: SG0610
            AVN: Avin_16590 Avin_20290
            SPL: Spea_2286
            SHL: Shal_2008
            CSA: Csal_2609
            BMA: BMAA1076
            BMV: BMASAVP1_0068
            BML: BMA10229_0351
            BMN: BMA10247_A1235
            BPS: BPSS1235
            BPM: BURPS1710b_A0234
            BPL: BURPS1106A_A1653
            BPD: BURPS668_A1742
            BTE: BTH_II1176
            BUR: Bcep18194_B3068
            BCN: Bcen_5063
            BCH: Bcen2424_5797
            BCM: Bcenmc03_4382
            BCJ: BCAM0097
            BPH: Bphy_6662
            BGE: BC1002_5589
            HSE: Hsero_3396
            MLO: mlr4915
            SME: SMc01992
            SMD: Smed_0849
            ATU: Atu4318
            ARA: Arad_8677
            RET: RHE_PE00268(ype00129)
            REC: RHECIAT_PA0000213
            RLE: pRL110382
            RLT: Rleg2_5833
            RLG: Rleg_6746
            SNO: Snov_0847
            BID: Bind_2341 Bind_3810
            RSQ: Rsph17025_3580
            RDE: RD1_3623(xdh)
            PDE: Pden_2163
            DSH: Dshi_0551(xylD)
            GDI: GDI_3142
            GDJ: Gdia_3230
            RRU: Rru_A0252
            BFA: Bfae_15800
            BLJ: BLD_1700(tdh3)
            BAD: BAD_0317
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.9
            IUBMB Enzyme Nomenclature: 1.1.1.9
            ExPASy - ENZYME nomenclature database: 1.1.1.9
            BRENDA, the Enzyme Database: 1.1.1.9
            CAS: 9028-16-4
///
ENTRY       EC 1.1.1.10                 Enzyme
NAME        L-xylulose reductase;
            xylitol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming)
REACTION    xylitol + NADP+ = L-xylulose + NADPH + H+ [RN:R01904]
ALL_REAC    R01904
SUBSTRATE   xylitol [CPD:C00379];
            NADP+ [CPD:C00006]
PRODUCT     L-xylulose [CPD:C00312];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:2981816]
  AUTHORS   Doten RC, Mortlock RP.
  TITLE     Characterization of xylitol-utilizing mutants of Erwinia uredovora.
  JOURNAL   J. Bacteriol. 161 (1985) 529-33.
  ORGANISM  Erwinia uredovora
REFERENCE   2  [PMID:13654257]
  AUTHORS   HICKMAN J, ASHWELL G.
  TITLE     A sensitive and stereospecific enzymatic assay for xylulose.
  JOURNAL   J. Biol. Chem. 234 (1959) 758-61.
  ORGANISM  Cavia porcellus
REFERENCE   3  [PMID:13416220]
  AUTHORS   HOLLMANN S, TOUSTER O.
  TITLE     The L-xylulose-xylitol enzyme and other polyol dehydrogenases of
            guinea pig liver mitochondria.
  JOURNAL   J. Biol. Chem. 225 (1957) 87-102.
  ORGANISM  Cavia porcellus
REFERENCE   4  [PMID:13357463]
  AUTHORS   HUTCHESON RM, REYNOLDS VH, TOUSTER O.
  TITLE     The reduction of L-xylulose to xylitol by guinea pig liver
            mitochondria.
  JOURNAL   J. Biol. Chem. 221 (1956) 697-709.
  ORGANISM  Cavia porcellus
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec01100  Metabolic pathways
ORTHOLOGY   K03331  L-xylulose reductase
GENES       HSA: 51181(DCXR)
            PTR: 454983(DCXR)
            PON: 100451797
            MCC: 715513(DCXR)
            MMU: 67880(Dcxr)
            RNO: 171408(Dcxr)
            CFA: 475926(DCXR)
            AML: 100478538
            BTA: 526937(DCXR)
            ECB: 100147313
            MDO: 100029860
            GGA: 374066(DCXR)
            TGU: 100223059
            XLA: 734498(dcxr)
            XTR: 394704(dcxr)
            DRE: 550282(dcxr)
            SPU: 591319
            AME: 413567
            NVI: 100114175(NV17556)
            TCA: 659735
            CEL: R11D1.11(dhs-21)
            CBR: CBG08572(Cbr-dhs-21)
            BPD: BURPS668_1913
            MSM: MSMEG_3262
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.10
            IUBMB Enzyme Nomenclature: 1.1.1.10
            ExPASy - ENZYME nomenclature database: 1.1.1.10
            BRENDA, the Enzyme Database: 1.1.1.10
            CAS: 9028-17-5
///
ENTRY       EC 1.1.1.11                 Enzyme
NAME        D-arabinitol 4-dehydrogenase;
            D-arabitol dehydrogenase;
            arabitol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-arabinitol:NAD+ 4-oxidoreductase
REACTION    D-arabinitol + NAD+ = D-xylulose + NADH + H+ [RN:R05604]
ALL_REAC    R05604;
            (other) R00868
SUBSTRATE   D-arabinitol [CPD:C01904];
            NAD+ [CPD:C00003]
PRODUCT     D-xylulose [CPD:C00310];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13762204]
  AUTHORS   LIN EC.
  TITLE     An inducible D-arabitol dehydrogenase from Aerobacter aerogenes.
  JOURNAL   J. Biol. Chem. 236 (1961) 31-6.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
REFERENCE   2  [PMID:13786517]
  AUTHORS   WOOD WA, McDONOUGH MJ, JACOBS LB.
  TITLE     Rihitol and D-arabitol utilization by Aerobacter aerogenes.
  JOURNAL   J. Biol. Chem. 236 (1961) 2190-5.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec00051  Fructose and mannose metabolism
ORTHOLOGY   K00007  D-arabinitol 4-dehydrogenase
GENES       ECG: E2348C_2230(atlD)
            EOK: G2583_2617
            EFE: EFER_2176
            YPE: YPO2325(dalD)
            YPK: y2008
            YPA: YPA_1674
            YPN: YPN_1784
            YPM: YP_2112(dalD)
            YPP: YPDSF_0821
            YPG: YpAngola_A2216
            YPZ: YPZ3_1551(dalD)
            YPS: YPTB2244(dalD)
            YPI: YpsIP31758_1812
            YPY: YPK_1922
            YPB: YPTS_2320
            ETA: ETA_34090(dalD)
            EPY: EpC_36240(dalD)
            EAM: EAMY_3630(dalD)
            EAY: EAM_3408(dalD)
            EBI: EbC_20110(dalD)
            KPN: KPN_02543
            KPE: KPK_1622(dalD)
            KPU: KP1_3760
            KVA: Kvar_1520
            CKO: CKO_00692
            PAM: PANA_2657(dalD)
            TAU: Tola_3084
            RSO: RSc2129(dalD)
            BMA: BMA0344
            BMV: BMASAVP1_A0643
            BML: BMA10229_A2478
            BMN: BMA10247_0091
            BPS: BPSL0840(dalD)
            BPM: BURPS1710b_1047(dalD)
            BPL: BURPS1106A_0888
            BPD: BURPS668_0885
            BPR: GBP346_A0812
            BTE: BTH_I0703
            BVI: Bcep1808_2702
            BUR: Bcep18194_A5916
            BCN: Bcen_1975
            BCH: Bcen2424_2585
            BCM: Bcenmc03_2609
            BCJ: BCAL2798(dalD)
            BAM: Bamb_2633
            BAC: BamMC406_2504
            BMU: Bmul_0712
            BMJ: BMULJ_02548(mtlK)
            BXE: Bxe_A0730
            BPH: Bphy_0498
            BPY: Bphyt_3238
            BGL: bglu_1g29420
            BGE: BC1002_2497
            VEI: Veis_3167
            VAP: Vapar_1112
            VPE: Varpa_1195
            HSE: Hsero_0445(dalD)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.11
            IUBMB Enzyme Nomenclature: 1.1.1.11
            ExPASy - ENZYME nomenclature database: 1.1.1.11
            BRENDA, the Enzyme Database: 1.1.1.11
            CAS: 9028-18-6
///
ENTRY       EC 1.1.1.12                 Enzyme
NAME        L-arabinitol 4-dehydrogenase;
            pentitol-DPN dehydrogenase;
            L-arabitol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming)
REACTION    L-arabinitol + NAD+ = L-xylulose + NADH + H+ [RN:R01903]
ALL_REAC    R01903
SUBSTRATE   L-arabinitol [CPD:C00532];
            NAD+ [CPD:C00003]
PRODUCT     L-xylulose [CPD:C00312];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13692998]
  AUTHORS   CHIANG C, KNIGHT SG.
  TITLE     A new pathway of pentose metabolism.
  JOURNAL   Biochem. Biophys. Res. Commun. 3 (1960) 554-9.
  ORGANISM  Penicillium chrysogenum [GN:pcs]
REFERENCE   2  [PMID:13692999]
  AUTHORS   CHIANG C, KNIGHT SG.
  TITLE     L-Arabinose metabolism by cell-free extracts of Penicillium
            chrysogenum.
  JOURNAL   Biochim. Biophys. Acta. 46 (1961) 271-8.
  ORGANISM  Penicillium chrysogenum [GN:pcs]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec01100  Metabolic pathways
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.12
            IUBMB Enzyme Nomenclature: 1.1.1.12
            ExPASy - ENZYME nomenclature database: 1.1.1.12
            BRENDA, the Enzyme Database: 1.1.1.12
            CAS: 9028-19-7
///
ENTRY       EC 1.1.1.13                 Enzyme
NAME        L-arabinitol 2-dehydrogenase;
            L-arabinitol dehydrogenase (ribulose-forming);
            L-arabinitol (ribulose-forming) dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-arabinitol:NAD+ 2-oxidoreductase (L-ribulose-forming)
REACTION    L-arabinitol + NAD+ = L-ribulose + NADH + H+ [RN:R02441]
ALL_REAC    R02441
SUBSTRATE   L-arabinitol [CPD:C00532];
            NAD+ [CPD:C00003]
PRODUCT     L-ribulose [CPD:C00508];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13692999]
  AUTHORS   CHIANG C, KNIGHT SG.
  TITLE     L-Arabinose metabolism by cell-free extracts of Penicillium
            chrysogenum.
  JOURNAL   Biochim. Biophys. Acta. 46 (1961) 271-8.
  ORGANISM  Penicillium chrysogenum [GN:pcs]
PATHWAY     ec00040  Pentose and glucuronate interconversions
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.13
            IUBMB Enzyme Nomenclature: 1.1.1.13
            ExPASy - ENZYME nomenclature database: 1.1.1.13
            BRENDA, the Enzyme Database: 1.1.1.13
            CAS: 9028-20-0
///
ENTRY       EC 1.1.1.14                 Enzyme
NAME        L-iditol 2-dehydrogenase;
            polyol dehydrogenase;
            sorbitol dehydrogenase;
            L-iditol:NAD+ 5-oxidoreductase;
            L-iditol (sorbitol) dehydrogenase;
            glucitol dehydrogenase;
            L-iditol:NAD+ oxidoreductase;
            NAD+-dependent sorbitol dehydrogenase;
            NAD+-dependent sorbitol dehydrogenase;
            NAD+-sorbitol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-iditol:NAD+ 2-oxidoreductase
REACTION    L-iditol + NAD+ = L-sorbose + NADH + H+ [RN:R07145]
ALL_REAC    R07145;
            (other) R00875
SUBSTRATE   L-iditol [CPD:C01507];
            NAD+ [CPD:C00003]
PRODUCT     L-sorbose [CPD:C00247];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also acts on D-glucitol (giving D-fructose) and other closely
            related sugar alcohols.
REFERENCE   1
  AUTHORS   Bailey, J.P., Renz, C. and McGuinness, E.T.
  TITLE     Sorbitol dehydrogenase from horse liver: purification,
            characterization and comparative properties.
  JOURNAL   Comp. Biochem. Physiol. 69B (1981) 909-914.
REFERENCE   2  [PMID:6852349]
  AUTHORS   Burnell JN, Holmes RS.
  TITLE     Purification and properties of sorbitol dehydrogenase from mouse
            liver.
  JOURNAL   Int. J. Biochem. 15 (1983) 507-11.
  ORGANISM  Mus musculus [GN:mmu]
REFERENCE   3  [PMID:667078]
  AUTHORS   Leissing N, McGuinness ET.
  TITLE     Rapid affinity purification and properties of rat liver sorbitol
            dehydrogenase.
  JOURNAL   Biochim. Biophys. Acta. 524 (1978) 254-61.
  ORGANISM  Rattus norvegicus [GN:rno]
REFERENCE   4  [PMID:16660917]
  AUTHORS   Negm FB, Loescher WH.
  TITLE     Detection and Characterization of Sorbitol Dehydrogenase from Apple
            Callus Tissue.
  JOURNAL   Plant. Physiol. 64 (1979) 69-73.
  ORGANISM  Malus domestica
REFERENCE   5  [PMID:6870831]
  AUTHORS   O'Brien MM, Schofield PJ, Edwards MR.
  TITLE     Polyol-pathway enzymes of human brain. Partial purification and
            properties of sorbitol dehydrogenase.
  JOURNAL   Biochem. J. 211 (1983) 81-90.
  ORGANISM  Homo sapiens [GN:hsa]
PATHWAY     ec00051  Fructose and mannose metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K00008  L-iditol 2-dehydrogenase
GENES       HSA: 6652(SORD)
            PTR: 453394(SORD)
            PON: 100173784(SORD)
            MCC: 712784(SORD)
            MMU: 20322(Sord)
            RNO: 24788(Sord)
            CFA: 487535(SORD)
            AML: 100469986
            BTA: 508954(SORD)
            SSC: 100158181(SORD)
            ECB: 100070575
            MDO: 100012620
            GGA: 415332(SORD)
            TGU: 100226453
            XLA: 446317(sord)
            XTR: 496715(sord)
            DRE: 570613(MGC174502)
            BFO: BRAFLDRAFT_67673
            CIN: 100184593
            SPU: 585570
            DME: Dmel_CG1982(Sodh-1) Dmel_CG4649(Sodh-2)
            DPO: Dpse_GA26401
            DAN: Dana_GF18841
            DER: Dere_GG17814
            DPE: Dper_GL12569
            DSE: Dsec_GM23911
            DSI: Dsim_GD19902
            DWI: Dwil_GK13991
            DYA: Dyak_GE26061
            DGR: Dgri_GH14504
            DMO: Dmoj_GI22936
            DVI: Dvir_GJ15399
            AGA: AgaP_AGAP003583 AgaP_AGAP003584
            AAG: AaeL_AAEL011112 AaeL_AAEL011126
            CQU: CpipJ_CPIJ013378
            AME: 408871
            TCA: 661035
            API: 100159783
            PHU: Phum_PHUM242730
            ISC: IscW_ISCW022542
            CEL: R04B5.5 R04B5.6
            CBR: CBG08605
            NVE: NEMVE_v1g193535
            HMG: 100197994
            ATH: AT5G51970
            POP: POPTR_823499 POPTR_890818
            RCU: RCOM_1497640
            VVI: 100232980 100265888
            OSA: 4346217
            SBI: SORBI_07g025220
            ZMA: 100283066(sdh1)
            PPP: PHYPADRAFT_179590
            CME: CMA009C
            SCE: YDL246C(SOR2) YJR159W(SOR1)
            AGO: AGOS_ABR229C
            KLA: KLLA0D05511g
            VPO: Kpol_1058p11
            DHA: DEHA2E24332g
            PIC: PICST_40172(SOR3)
            YLI: YALI0E12463g
            NCR: NCU00643 NCU00891 NCU07022
            PAN: PODANSg076 PODANSg09492 PODANSg3737
            MGR: MGG_01231(MG01231.4) MGG_13917(MG07936.4)
            FGR: FG00655.1 FG08942.1 FG09599.1
            SSL: SS1G_05959 SS1G_09416 SS1G_12678
            BFU: BC1G_05697 BC1G_12937 BC1G_15180
            ANI: AN0942.2 AN8109.2
            AFM: AFUA_1G11020 AFUA_1G11030 AFUA_1G14390 AFUA_1G16270
                 AFUA_8G02000
            NFI: NFIA_009170
            AOR: AO090005001078 AO090009000575 AO090011000369 AO090020000647
                 AO090023000346 AO090103000393 AO090701000411
            ANG: An01g10920 An07g01290 An08g09380 An09g03900 An16g01710
            AFV: AFLA_049230 AFLA_083240
            ACT: ACLA_019290 ACLA_021030
            PCS: Pc14g00190 Pc16g10230 Pc16g10990 Pc16g12970 Pc21g19650
                 Pc21g23190
            CPW: CPC735_009740 CPC735_042480
            URE: UREG_07050 UREG_07581
            PNO: SNOG_13783 SNOG_14274
            TML: GSTUM_00001999001 GSTUM_00008518001
            SPO: SPBC1773.05c(tms1)
            CNE: CNA01050 CNG00100 CNH02960
            CNB: CNBG4640 CNBL3030
            LBC: LACBIDRAFT_174052
            CCI: CC1G_00854
            SCM: SCHCODRAFT_85048
            UMA: UM00412.1 UM02150.1
            ECI: UTI89_C1970(ydjJ) UTI89_C1972(ydjL)
            ECT: ECIAI39_1279(ydjJ)
            SEA: SeAg_B4593
            YPE: YPO2502(gutB)
            YPK: y1686
            YPA: YPA_1997
            YPN: YPN_2096
            YPM: YP_2317(gutB)
            YPP: YPDSF_1914
            YPG: YpAngola_A1762
            YPS: YPTB2538(gutB)
            YPI: YpsIP31758_1506
            YPY: YPK_1610
            HCH: HCH_02471
            BMA: BMA1195
            BMV: BMASAVP1_A1639
            BML: BMA10229_A0301
            BMN: BMA10247_0860
            BPS: BPSL1790
            BPM: BURPS1710b_2072(gutB)
            BPL: BURPS1106A_1924
            BPD: BURPS668_1911
            BTE: BTH_I2432
            BUR: Bcep18194_B0887 Bcep18194_B3148 Bcep18194_C7277 Bcep18194_C7304
            BCN: Bcen_3550
            BCM: Bcenmc03_5466
            BMU: Bmul_3786
            POL: Bpro_1286
            DAC: Daci_4579
            VAP: Vapar_0341
            MLO: mlr3340
            MES: Meso_3701
            ATU: Atu3164
            RET: RHE_CH02965(ypch01030) RHE_PD00350 RHE_PE00181(ype00084)
            RLE: RL0651
            BJA: bll5566
            RDE: RD1_0514(gutB) RD1_3810(gutB)
            BSU: BSU06150(gutB)
            BSS: BSUW23_03100(gutB)
            BHA: BH0187(gutB) BH0189
            BCZ: BCZK0739(gutB)
            BAY: RBAM_006540(gutB)
            BAO: BAMF_0606(gutB3)
            BAE: BATR1942_00565
            BCL: ABC1039(gutB) ABC3342 ABC3344 ABC4080
            BPU: BPUM_1170(gutB)
            BMD: BMD_3588(gutB)
            OIH: OB2750 OB2752 OB3238 OB3258
            SAU: SA0239 SA0240
            SAV: SAV0248 SAV0250
            SAW: SAHV_0247 SAHV_0249
            SAH: SaurJH1_0239 SaurJH1_0241
            SAJ: SaurJH9_0233 SaurJH9_0235
            SAM: MW0224 MW0226
            SAS: SAS0224 SAS0226
            SAR: SAR0243 SAR0245
            SAC: SACOL0233(gutB) SACOL0235
            SAX: USA300HOU_0259(gutB) USA300HOU_0261
            SAA: SAUSA300_0242(gutB) SAUSA300_0244
            SAO: SAOUHSC_00217 SAOUHSC_00219
            SAE: NWMN_0183 NWMN_0184
            SAB: SAB0187 SAB0189
            SHA: SH0215(gutB)
            SSP: SSP0366
            SLG: SLGD_02536
            LMO: lmo0506 lmo2663 lmo2664
            LMF: LMOf2365_0535 LMOf2365_2643 LMOf2365_2644
            LMH: LMHCC_2134 LMHCC_2870
            LMC: Lm4b_00528 Lm4b_02637
            LMN: LM5578_0196 LM5578_0529
            LMY: LM5923_0196 LM5923_0528
            LIN: lin0506 lin2812 lin2813
            LWE: lwe2612 lwe2613
            LSG: lse_2567 lse_2568
            LPL: lp_3545(gutB)
            LPJ: JDM1_2831(gutB)
            CPF: CPF_0732
            CTH: Cthe_0388
            CDF: CD0490 CD2323 CD2324(gatD)
            CDC: CD196_0447 CD196_2167(gatD)
            CDL: CDR20291_0433 CDR20291_2213(gatD)
            CBO: CBO3418
            CBA: CLB_3475
            CBH: CLC_3363
            CBY: CLM_3884
            CBL: CLK_2861
            CBK: CLL_A3334
            CBB: CLD_1088
            CBI: CLJ_B3725
            CBT: CLH_2693
            CBF: CLI_3601
            CBE: Cbei_0223 Cbei_0544
            CCE: Ccel_1029 Ccel_2189
            CST: CLOST_0774(ydjJ)
            AMT: Amet_0590
            PTH: PTH_0271(tdh)
            CHY: CHY_1307(gutB)
            TOC: Toce_0293 Toce_1442 Toce_1443
            TTM: Tthe_1909 Tthe_1910
            MSM: MSMEG_3605
            MVA: Mvan_5590
            MKM: Mkms_2830
            RHA: RHA1_ro02784 RHA1_ro02809 RHA1_ro03291
            AAU: AAur_2421
            RSA: RSal33209_3124
            BCV: Bcav_4187
            BFA: Bfae_28190
            PAC: PPA0918
            NDA: Ndas_4221
            FRE: Franean1_7070
            NML: Namu_3324
            GOB: Gobs_2793
            CWO: Cwoe_5082
            TDE: TDE0075
            ABA: Acid345_1743 Acid345_1744
            ACA: ACP_0816
            SUS: Acid_1264
            CPI: Cpin_5213
            STR: Sterm_0041 Sterm_3153 Sterm_3155
            RBA: RB3488
            TEL: tll0970 tlr1436
            GVI: glr0369 glr0940
            ANA: alr2335 alr5117
            NPU: Npun_F2709 Npun_R1726
            AVA: Ava_0154 Ava_1615 Ava_2347
            NAZ: Aazo_1007 Aazo_3723
            AMR: AM1_4548
            DET: DET0125
            DEH: cbdb_A145
            DGE: Dgeo_2864
            DDR: Deide_3p02130
            TRA: Trad_2181 Trad_2895
            DTH: DICTH_0120
            DTU: Dtur_0389
            TYE: THEYE_A0455 THEYE_A1024
            TTR: Tter_2272
            SSO: SSO3237
            STO: ST2341
            SAI: Saci_0410
            SIS: LS215_2293
            SIA: M1425_2130
            SIM: M1627_2210
            SID: M164_2134
            SIY: YG5714_2257
            SIN: YN1551_0659
            SII: LD85_2397
            MSE: Msed_0196
            NMR: Nmar_1079
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.14
            IUBMB Enzyme Nomenclature: 1.1.1.14
            ExPASy - ENZYME nomenclature database: 1.1.1.14
            BRENDA, the Enzyme Database: 1.1.1.14
            CAS: 9028-21-1
///
ENTRY       EC 1.1.1.15                 Enzyme
NAME        D-iditol 2-dehydrogenase;
            D-sorbitol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-iditol:NAD+ 2-oxidoreductase
REACTION    D-iditol + NAD+ = D-sorbose + NADH + H+ [RN:R02896]
ALL_REAC    R02896;
            (other) R00875 R05831 R08536
SUBSTRATE   D-iditol [CPD:C01489];
            NAD+ [CPD:C00003]
PRODUCT     D-sorbose [CPD:C00764];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also converts xylitol into L-xylulose and L-glucitol into
            L-fructose.
REFERENCE   1  [PMID:13373783]
  AUTHORS   SHAW DR.
  TITLE     Polyol dehydrogenases.  3.  Galactitol dehydrogenase and D-iditol
            dehydrogenase.
  JOURNAL   Biochem. J. 64 (1956) 394-405.
  ORGANISM  Pseudomonas sp.
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec00051  Fructose and mannose metabolism
            ec01100  Metabolic pathways
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.15
            IUBMB Enzyme Nomenclature: 1.1.1.15
            ExPASy - ENZYME nomenclature database: 1.1.1.15
            BRENDA, the Enzyme Database: 1.1.1.15
            CAS: 9028-22-2
///
ENTRY       EC 1.1.1.16                 Enzyme
NAME        galactitol 2-dehydrogenase;
            dulcitol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     galactitol:NAD+ 2-oxidoreductase
REACTION    galactitol + NAD+ = D-tagatose + NADH + H+ [RN:R02928]
ALL_REAC    R02928
SUBSTRATE   galactitol [CPD:C01697];
            NAD+ [CPD:C00003]
PRODUCT     D-tagatose [CPD:C00795];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also converts other alditols containing an L-threo-configuration
            adjacent to a primary alcohol group into the corresponding sugars.
REFERENCE   1  [PMID:13373783]
  AUTHORS   SHAW DR.
  TITLE     Polyol dehydrogenases.  3.  Galactitol dehydrogenase and D-iditol
            dehydrogenase.
  JOURNAL   Biochem. J. 64 (1956) 394-405.
  ORGANISM  Pseudomonas sp.
PATHWAY     ec00052  Galactose metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.16
            IUBMB Enzyme Nomenclature: 1.1.1.16
            ExPASy - ENZYME nomenclature database: 1.1.1.16
            BRENDA, the Enzyme Database: 1.1.1.16
            CAS: 9028-23-3
///
ENTRY       EC 1.1.1.17                 Enzyme
NAME        mannitol-1-phosphate 5-dehydrogenase;
            hexose reductase;
            mannitol 1-phosphate dehydrogenase;
            D-mannitol-1-phosphate dehydrogenase;
            fructose 6-phosphate reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-mannitol-1-phosphate:NAD+ 5-oxidoreductase
REACTION    D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+
            [RN:R00758]
ALL_REAC    R00758 > R02703
SUBSTRATE   D-mannitol 1-phosphate [CPD:C00644];
            NAD+ [CPD:C00003]
PRODUCT     D-fructose 6-phosphate [CPD:C00085];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:14367396]
  AUTHORS   MARMUR J, HOTCHKISS RD.
  TITLE     Mannitol metabolism, a transferable property of pneumococcus.
  JOURNAL   J. Biol. Chem. 214 (1955) 383-96.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   2
  AUTHORS   Wolfe, J.B. and Kaplan, N.O.
  TITLE     Hexose phosphate and hexose reductase. A. D-Mannitol-1-phosphate
            dehydrogenase from E. coli.
  JOURNAL   Methods Enzymol. 1 (1955) 346-348.
REFERENCE   3  [PMID:13295236]
  AUTHORS   WOLFF JB, KAPLAN NO.
  TITLE     D-Mannitol 1-phosphate dehydrogenase from Escherichia coli.
  JOURNAL   J. Biol. Chem. 218 (1956) 849-69.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00051  Fructose and mannose metabolism
ORTHOLOGY   K00009  mannitol-1-phosphate 5-dehydrogenase
GENES       ZMA: 100382636
            NCR: NCU07318
            MGR: MGG_10503(MG10503.4)
            SSL: SS1G_14022
            BFU: BC1G_11550
            ANI: AN5975.2
            AFM: AFUA_2G10660
            NFI: NFIA_086010
            AOR: AO090011000576
            ANG: An02g05830
            AFV: AFLA_043980
            ACT: ACLA_069650
            PCS: Pc22g20800
            CIM: CIMG_07907
            CPW: CPC735_019790
            URE: UREG_02218
            PNO: SNOG_12666
            ECO: b3600(mtlD)
            ECJ: JW3574(mtlD)
            ECD: ECDH10B_3781(mtlD)
            EBW: BWG_3290(mtlD)
            ECE: Z5024(mtlD)
            ECS: ECs4476
            ECF: ECH74115_4970(mtlD)
            ETW: ECSP_4593(mtlD)
            EOJ: ECO26_5000(mtlD)
            EOI: ECO111_4421(mtlD)
            EOH: ECO103_4582(mtlD)
            ECG: E2348C_3846(mtlD)
            EOK: G2583_4336(mtlD)
            ECC: c4417(mtlD)
            ECP: ECP_3698
            ECI: UTI89_C4138(mtlD)
            ECV: APECO1_2857(mtlD)
            ECX: EcHS_A3807(mtlD)
            ECW: EcE24377A_4099(mtlD)
            ECM: EcSMS35_3933(mtlD)
            ECY: ECSE_3879
            ECR: ECIAI1_3770(mtlD)
            ECQ: ECED1_4282(mtlD)
            ECK: EC55989_4064(mtlD)
            ECT: ECIAI39_4115(mtlD)
            EUM: ECUMN_4111(mtlD)
            ECZ: ECS88_4013(mtlD)
            ECL: EcolC_0112
            EBR: ECB_03455(mtlD)
            EBD: ECBD_0128
            EFE: EFER_3591(mtlD)
            STY: STY4110(mtlD)
            STT: t3833(mtlD)
            STM: STM3686(mtlD)
            SPT: SPA3538(mtlD)
            SEK: SSPA3303
            SPQ: SPAB_04579
            SEI: SPC_3767
            SEC: SC3610(mtlD)
            SEH: SeHA_C4009(mtlD)
            SEE: SNSL254_A3964(mtlD)
            SEW: SeSA_A3886(mtlD)
            SEA: SeAg_B3902(mtlD)
            SED: SeD_A4071(mtlD)
            SEG: SG3744(mtlD)
            SET: SEN3508(mtlD)
            SES: SARI_03954
            YPE: YPO4067(mtlD)
            YPK: y4086(mtlD)
            YPA: YPA_3015
            YPN: YPN_3714
            YPM: YP_3978(mtlD2)
            YPP: YPDSF_0026
            YPG: YpAngola_A3779(mtlD)
            YPZ: YPZ3_3489(mtlD)
            YPS: YPTB3919(mtlD)
            YPI: YpsIP31758_4127(mtlD)
            YPY: YPK_0027
            YPB: YPTS_4139
            YEN: YE4147(mtlD)
            SFL: SF3634(mtlD)
            SFX: S4134(mtlD)
            SFV: SFV_3937(mtlD)
            SSN: SSON_3808(mtlD)
            SBO: SBO_3598(mtlD)
            SBC: SbBS512_E4017(mtlD)
            ECA: ECA0088(mtlD)
            PCT: PC1_4164
            PWA: Pecwa_4446
            ETA: ETA_34190(mtlD)
            EPY: EpC_36340(mtlD)
            EAM: EAMY_3641(mtlD)
            EAY: EAM_3417(mtlD)
            EBI: EbC_45230(mtlD)
            BUC: BU571(mtlD)
            BAS: BUsg551(mtlD)
            BAB: bbp516(mtlD)
            BAP: BUAP5A_564(mtlD)
            BAU: BUAPTUC7_565(mtlD)
            SGL: SG0015
            ENT: Ent638_0135
            ENC: ECL_00169
            ESC: Entcl_0144
            ESA: ESA_03878
            CTU: Ctu_01280(mtlD)
            KPN: KPN_03943(mtlD)
            KPE: KPK_0152(mtlD)
            KPU: KP1_5290(mtlD)
            KVA: Kvar_0158
            CKO: CKO_05055
            CRO: ROD_42211(mtlD)
            SPE: Spro_0073
            DDC: Dd586_0062
            DDD: Dda3937_00994(mtlD)
            DZE: Dd1591_0053
            PAM: PANA_0111(mtlD)
            PVA: Pvag_3336(mtlD)
            PAO: Pat9b_0085
            HSO: HS_1251(mtlD)
            HSM: HSM_0826
            PMU: PM1062(mtlD)
            MSU: MS0410(mtlD)
            APL: APL_1629(mtlD)
            APJ: APJL_1662(mtlD)
            APA: APP7_1691
            ASU: Asuc_0456
            AAT: D11S_1815
            VCH: VCA1046
            VCO: VC0395_0195(mtlD)
            VCM: VCM66_A1004(mtlD)
            VCJ: VCD_000294
            VVU: VV1_0639
            VVY: VV0504
            VVM: VVM_04216
            VPA: VP0369
            VHA: VIBHAR_00833
            VEX: VEA_001633
            VSA: VSAL_I2814(mtlD)
            PPR: PBPRB0362
            PIN: Ping_0089
            AHA: AHA_0550
            ASA: ASA_3756(mtlD)
            TAU: Tola_0284
            BSU: BSU03990(mtlD)
            BSS: BSUW23_02065(mtlD)
            BHA: BH3851(mtlD)
            BLI: BL02815(mtlD)
            BLD: BLi00507(mtlD)
            BAY: RBAM_004250(mtlD)
            BAO: BAMF_0368(mtlD)
            BAE: BATR1942_20710
            BCL: ABC2926(mtlD)
            BPU: BPUM_0371(mtlD)
            BPF: BpOF4_05135(mtlD)
            BMQ: BMQ_0204
            BMD: BMD_0198
            OIH: OB2600
            GKA: GK1945
            GTN: GTNG_1844
            GYM: GYMC10_6187
            GYC: GYMC61_2794
            GYA: GYMC52_1924
            GCT: GC56T3_1569
            GMC: GY4MC1_2237
            AFL: Aflv_1562(mtlD)
            SAU: SA1963(mtlD)
            SAV: SAV2159(mtlD)
            SAW: SAHV_2143(mtlD)
            SAH: SaurJH1_2229
            SAJ: SaurJH9_2191
            SAM: MW2085(mtlD)
            SAS: SAS2060
            SAR: SAR2247(mtlD)
            SAC: SACOL2149(mtlD)
            SAX: USA300HOU_2149(mtlD)
            SAA: SAUSA300_2108(mtlD)
            SAO: SAOUHSC_02403
            SAE: NWMN_2060(mtlD)
            SAD: SAAV_2213(mtlD)
            SAB: SAB2039(mtlD)
            SHA: SH0232(mtlD)
            SSP: SSP0725
            SCA: Sca_1661(mtlD)
            SSD: SPSINT_1822
            ESI: Exig_1718
            EAT: EAT1b_2204
            BBE: BBR47_56360
            PJD: Pjdr2_6223
            PPY: PPE_03539
            PPM: PPSC2_c4042
            AAC: Aaci_0223
            LLA: L33416(mtlD)
            LLK: LLKF_0026(mtlD)
            LLC: LACR_0030
            LLM: llmg_0025(mtlD)
            SPN: SP_0397
            SPD: SPD_0363
            SPR: spr0359(mtlD)
            SPW: SPCG_0397(mtlD)
            SPX: SPG_0365
            SNE: SPN23F_03730(mtlD)
            SPV: SPH_0507
            SNM: SP70585_0470
            SJJ: SPJ_0386
            SNB: SP670_0469
            SMU: SMU.1182(mtlD)
            SMC: SmuNN2025_0863(mtlD)
            SUB: SUB0287 SUB0994(mtlD)
            SGA: GALLO_0996(mtlD)
            LPL: lp_0233(mtlD)
            LPJ: JDM1_0217(mtlD)
            LPS: LPST_C0190(mtlD)
            LSL: LSL_1618(mtlD)
            LDE: LDBND_0442(mtlD)
            LCA: LSEI_2885
            LCB: LCABL_04520 LCABL_31030(mtlD)
            LCZ: LCAZH_0415 LCAZH_2892
            LRH: LGG_02909(mtlD)
            LRL: LC705_02873(mtlD)
            LCR: LCRIS_00469(mtlD)
            LAM: LA2_02470
            EFA: EF0413(mtlD)
            CAC: CA_C0157(mtlD)
            CDF: CD2331(mtlD)
            CDC: CD196_2174(mtlD)
            CDL: CDR20291_2220(mtlD)
            CBE: Cbei_0245 Cbei_0531
            CCB: Clocel_2405
            EHA: Ethha_2757
            TTE: TTE0342(mtlD)
            TEX: Teth514_0271
            TPD: Teth39_1939
            TIT: Thit_0305
            TMT: Tmath_0378
            TBO: Thebr_1986
            TOC: Toce_0055
            MPN: MPN652(mtlD)
            MPU: MYPU_7500(mtlD)
            MMY: MSC_0017(mtlD)
            MHY: mhp568(mtlD)
            MHJ: MHJ_0553(mtlD)
            MHP: MHP7448_0549(mtlD)
            MCP: MCAP_0032
            MCO: MCJ_006410(mtlD)
            MHR: MHR_0170(mtlD)
            MLC: MSB_A0038
            LXX: Lxx00800(mtlD)
            CMI: CMM_2589(mtlD)
            CMS: CMS_0311(mtlD)
            ART: Arth_4003
            AAU: AAur_3858(mtlD)
            ACH: Achl_3788
            BFA: Bfae_07050
            NML: Namu_0056
            STR: Sterm_1384 Sterm_1848 Sterm_3835
            IPO: Ilyop_1254
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.17
            IUBMB Enzyme Nomenclature: 1.1.1.17
            ExPASy - ENZYME nomenclature database: 1.1.1.17
            BRENDA, the Enzyme Database: 1.1.1.17
            CAS: 9028-24-4
///
ENTRY       EC 1.1.1.18                 Enzyme
NAME        inositol 2-dehydrogenase;
            myo-inositol 2-dehydrogenase;
            myo-inositol:NAD+ oxidoreductase;
            inositol dehydrogenase;
            myo-inositol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     myo-inositol:NAD+ 2-oxidoreductase
REACTION    myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH +
            H+ [RN:R01183]
ALL_REAC    R01183
SUBSTRATE   myo-inositol [CPD:C00137];
            NAD+ [CPD:C00003]
PRODUCT     2,4,6/3,5-pentahydroxycyclohexanone [CPD:C00691];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:5905122]
  AUTHORS   Berman T, Magasanik B.
  TITLE     The pathway of myo-inositol degradation in Aerobacter aerogenes.
            Dehydrogenation and dehydration.
  JOURNAL   J. Biol. Chem. 241 (1966) 800-6.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
REFERENCE   2  [PMID:13292912]
  AUTHORS   LARNER J, JACKSON WT, GRAVES DJ, STAMER JR.
  TITLE     Inositol dehydrogenase from Aerobacter aerogenes.
  JOURNAL   Arch. Biochem. Biophys. 60 (1956) 352-63.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
REFERENCE   3  [PMID:4351258]
  AUTHORS   Vidal-Leiria M, van Uden N.
  TITLE     Inositol dehydrogenase from the yeast Cryptococcus melibiosum.
  JOURNAL   Biochim. Biophys. Acta. 293 (1973) 295-303.
  ORGANISM  Cryptococcus melibiosum
PATHWAY     ec00521  Streptomycin biosynthesis
            ec00562  Inositol phosphate metabolism
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00010  myo-inositol 2-dehydrogenase
GENES       BFO: BRAFLDRAFT_69830
            AME: 552024
            NVI: 100120331(NV11389)
            TCA: 658577
            CME: CMF086C CMR475C
            DHA: DEHA2F22044g
            PIC: PICST_64256 PICST_78306
            FGR: FG04702.1 FG08414.1
            ANI: AN5984.2
            AFM: AFUA_2G10240
            NFI: NFIA_085630
            AOR: AO090011000611 AO090011000612
            ANG: An09g01970 An16g04750
            AFV: AFLA_044390
            ACT: ACLA_069260
            PCS: Pc22g20320
            PNO: SNOG_07471
            CNB: CNBC0340
            PTI: PHATRDRAFT_51869
            TPS: THAPSDRAFT_8703
            PIF: PITG_18299
            ECQ: ECED1_0304(iolG) ECED1_0315
            STM: STM4425 STM4433
            SPQ: SPAB_05572 SPAB_05582
            SEA: SeAg_B4707 SeAg_B4715
            YPA: YPA_2521 YPA_2522
            YPN: YPN_1063 YPN_1064
            YPP: YPDSF_2674 YPDSF_2675
            YPZ: YPZ3_2278 YPZ3_2279
            YPS: YPTB1073
            YPI: YpsIP31758_2974
            YPY: YPK_3046
            YPB: YPTS_1129
            YEN: YE4026(idh)
            ECA: ECA1458(idhA)
            PCT: PC1_1336
            PWA: Pecwa_1046 Pecwa_3001
            ETA: ETA_32880(iolG)
            EPY: EpC_34990(iolG)
            EAM: EAMY_3507(iolG)
            EAY: EAM_3304(idh)
            EBI: EbC_21670 EbC_42640(iolG) EbC_42810
            PLU: plu1804
            PAY: PAU_02711(idhA)
            ENC: ECL_03807(iolG)
            ESC: Entcl_1259
            CTU: Ctu_08980(iolG)
            KPN: KPN_00507 KPN_04675
            KPE: KPK_4081(idhA) KPK_4990(idh)
            KPU: KP1_0560 KP1_1420
            KVA: Kvar_3231 Kvar_3871 Kvar_4579
            CKO: CKO_03991
            SPE: Spro_2393 Spro_4658
            EIC: NT01EI_2135
            DDC: Dd586_0708
            DDD: Dda3937_01203(idhA)
            DZE: Dd1591_3339
            XNE: XNC1_2983
            PAM: PANA_3736(idh)
            PVA: Pvag_3022(iolG) Pvag_pPag10076(idhA) Pvag_pPag10103
                 Pvag_pPag30219(iolG)
            PAO: Pat9b_0381 Pat9b_0388 Pat9b_3719 Pat9b_4536 Pat9b_5337
            HAP: HAPS_1534(iolG)
            HSO: HS_1576(iolG)
            HSM: HSM_0435
            AAP: NT05HA_1322
            AAT: D11S_1813
            PPR: PBPRB0470
            PST: PSPTO_3047 PSPTO_3494(iolG)
            PSB: Psyr_3268
            PSP: PSPPH_2336 PSPPH_3188(iolG)
            PFL: PFL_2591
            PFS: PFLU2385 PFLU2580
            AVN: Avin_09420 Avin_31420 Avin_50110(idh)
            LPN: lpg1652
            LPF: lpl1618(iolG)
            LPP: lpp1623(iolG)
            LPC: LPC_1082(iolG)
            LPA: lpa_02388
            LLO: LLO_2235(iolG)
            HCH: HCH_05773
            HEL: HELO_4239(idhA)
            MMW: Mmwyl1_1599
            RSO: RSc1246(iolG)
            RSC: RCFBP_20180(iolG) RCFBP_20196
            RSL: RPSI07_2116(iolG) RPSI07_2135
            BMA: BMA0918
            BMV: BMASAVP1_A1449 BMASAVP1_A1451
            BML: BMA10229_A0430 BMA10229_A0431
            BMN: BMA10247_0731 BMA10247_0732
            BPS: BPSL1988 BPSL1989
            BPM: BURPS1710b_1836(idhA) BURPS1710b_1838
            BPL: BURPS1106A_1682 BURPS1106A_1683
            BPD: BURPS668_1660 BURPS668_1661
            BPR: GBP346_A1705 GBP346_A1706
            BTE: BTH_I2641 BTH_I2642
            BVI: Bcep1808_1391
            BUR: Bcep18194_A4572 Bcep18194_A6014
            BCN: Bcen_0946 Bcen_2075
            BCH: Bcen2424_1428 Bcen2424_2686
            BCM: Bcenmc03_1406 Bcenmc03_2715
            BCJ: BCAL0917 BCAL1435(idh)
            BAM: Bamb_1308 Bamb_2740 Bamb_3338
            BAC: BamMC406_1347
            BMU: Bmul_0611 Bmul_1887
            BMJ: BMULJ_01354(iolG) BMULJ_02649(iolG)
            BXE: Bxe_A1331 Bxe_A1332
            BPH: Bphy_1594 Bphy_1595
            BPY: Bphyt_2803 Bphyt_2804
            BGL: bglu_1g21980 bglu_1g21990
            BGE: BC1002_2041 BC1002_2042
            VEI: Veis_0056 Veis_1850
            DAC: Daci_2925
            HSE: Hsero_2421 Hsero_2422
            LCH: Lcho_0840 Lcho_2412 Lcho_3282 Lcho_3283
            MLO: mll1000 mll4991
            MCI: Mesci_0496
            SME: SM_b20899(idhA)
            SMD: Smed_0190 Smed_4469
            RHI: NGR_b19660 NGR_c24190(idhA2) NGR_c26010(iolG)
            ATU: Atu4012(idhA) Atu4554(iolG)
            ARA: Arad_0103(idhA) Arad_0116 Arad_3362(idhA) Arad_8534(idhA)
            AVI: Avi_0074(idhA)
            RET: RHE_CH01209(ypch00405) RHE_CH02357(ypch00774) RHE_CH03170(idhA)
            REC: RHECIAT_CH0003391(idhA) RHECIAT_PC0000701
            RLE: RL3622
            RLT: Rleg2_2918 Rleg2_4853
            RLG: Rleg_3183 Rleg_5295
            BME: BMEII0574
            BMI: BMEA_B0686
            BMF: BAB2_0528
            BMB: BruAb2_0519(idhA)
            BMC: BAbS19_II04980
            BMS: BRA0711(idhA)
            BMT: BSUIS_B0698
            BOV: BOV_A0667(idhA)
            BCS: BCAN_B0716(mocA)
            BMR: BMI_II705(idhA)
            OAN: Oant_3835
            BRA: BRADO2244(idhA)
            BBT: BBta_0488(idhA)
            MNO: Mnod_7807
            BID: Bind_2828
            CCR: CC_1296
            CCS: CCNA_01354(idhA)
            AEX: Astex_3578
            SIT: TM1040_3352
            RSP: RSP_3283 RSP_3670
            RSH: Rsph17029_3405 Rsph17029_4015
            RSK: RSKD131_3457 RSKD131_3900
            JAN: Jann_1416
            RDE: RD1_0217(idhA) RD1_3876
            PDE: Pden_1678
            DSH: Dshi_1265(idhA)
            GOX: GOX1187
            ACR: Acry_2320 Acry_2329
            GDI: GDI_0366(idhA)
            GDJ: Gdia_2417
            AZL: AZL_b00980(iolG)
            APB: SAR116_0266
            BSU: BSU27770(yrbE) BSU39700(iolG)
            BSS: BSUW23_02820(idh) BSUW23_05500(yisS) BSUW23_13450(yrbE)
                 BSUW23_19810(iolG)
            BHA: BH2220 BH2221 BH2316(iolG)
            BAN: BA_2511
            BAR: GBAA_2511
            BAT: BAS2332
            BAH: BAMEG_2091
            BAI: BAA_2567
            BAL: BACI_c24800
            BCZ: BCZK2251 pE33L466_0294(iolG) pE33L466_0299(iolG)
            BCU: BCAH820_2526
            BCX: BCA_2596
            BTK: BT9727_2295
            BTL: BALH_2257
            BLI: BL00240(idh) BL01338(yisS)
            BLD: BLi01181(yisS) BLi04245(idh)
            BAY: RBAM_036720(iolG)
            BAO: BAMF_1169(yisS) BAMF_3782(iolG)
            BAE: BATR1942_03040 BATR1942_17860
            BCL: ABC0427(iolG) ABC0429
            BMQ: BMQ_0488(iolG) BMQ_3466(iolG) BMQ_pBM70037
            BMD: BMD_0491(iolG) BMD_3461(iolG)
            GKA: GK1897
            GTN: GTNG_1811 GTNG_1817
            GYM: GYMC10_3672
            GMC: GY4MC1_2179
            PJD: Pjdr2_1952
            LPL: lp_3605(iolG1) lp_3606(iolG2) lp_3608(iolG3) lp_3612(iolG4)
            LCB: LCABL_02210(iolG1) LCABL_02220(iolG2)
            LCZ: LCAZH_0256 LCAZH_0257
            LRH: LGG_00266(iolG1) LGG_00267(iolG2)
            LRL: LC705_00257(iolG1) LC705_00258(iolG2)
            CPE: CPE0090 CPE0093
            CPF: CPF_0085 CPF_0088
            CTC: CTC00511 CTC00513
            CBK: CLL_A1305
            CBT: CLH_1256
            CBE: Cbei_4547
            CSH: Closa_3962
            CLO: HMPREF0868_0020 HMPREF0868_0021
            CSC: Csac_2738
            HAS: Halsa_0171
            MHY: mhp144 mhp150
            MHJ: MHJ_0222 MHJ_0228
            MHP: MHP7448_0228 MHP7448_0235
            MSM: MSMEG_4650 MSMEG_4666
            MVA: Mvan_0387 Mvan_3968 Mvan_4020
            MGI: Mflv_2598 Mflv_2613
            MSP: Mspyr1_20330 Mspyr1_20480
            CGL: NCgl0161(cgl0164) NCgl2029(cgl2110) NCgl2957(cgl3062)
                 NCgl2958(cgl3063)
            CGB: cg0204(iolG) cg2313(idhA3) cg3391(idhA1) cg3392(idhA2)
            CGT: cgR_0243 cgR_1994 cgR_2947 cgR_2948
            RHA: RHA1_ro01355 RHA1_ro02992 RHA1_ro03886 RHA1_ro05267
            RER: RER_20160(idh) RER_20290(idh) RER_20320 RER_20390
            ROP: ROP_05130(idh) ROP_05170(idh) ROP_10710 ROP_37550(idh)
                 ROP_53120
            GBR: Gbro_1982 Gbro_3594 Gbro_3609
            TPR: Tpau_1361
            SCO: SCO6255(SCAH10.20c) SCO6984(SC8F11.10c) SCO7254(SC5H1.38)
            SMA: SAV_1234(iolG) SAV_1985 SAV_7188
            SGR: SGR_1277 SGR_5937(strI)
            SCB: SCAB_16031 SCAB_18231 SCAB_9601
            LXX: Lxx24320
            CMI: CMM_0793
            ART: Arth_0825 Arth_0833 Arth_0834
            AAU: AAur_1982 AAur_1991 AAur_1993 AAur_1994
            ACH: Achl_0120 Achl_0146 Achl_0942
            RSA: RSal33209_0365 RSal33209_3165
            BCV: Bcav_0731 Bcav_1659
            PAC: PPA0469
            PAK: HMPREF0675_3511
            PFR: PFREUD_19030(iolG1)
            KFL: Kfla_1684 Kfla_1694 Kfla_1699
            SRO: Sros_5561 Sros_8496
            FRA: Francci3_3374
            ACE: Acel_1805 Acel_1809 Acel_1814
            NML: Namu_1848 Namu_3353 Namu_4534
            GOB: Gobs_2747 Gobs_2759 Gobs_2766
            KRA: Krad_0031 Krad_0276 Krad_4051 Krad_4156
            SEN: SACE_2980(iolG) SACE_3276(idhA2) SACE_4537(iolG)
                 SACE_4657(iolG) SACE_5193(iolG)
            TBI: Tbis_3080
            AMD: AMED_1890(iolG)
            AMI: Amir_6853
            STP: Strop_2344
            SAQ: Sare_2488
            MAU: Micau_2610
            MIL: ML5_0854 ML5_5784
            CAI: Caci_4486
            SNA: Snas_0653
            AHE: Arch_0042
            BBI: BBIF_1355(iolG)
            BBP: BBPR_1400
            RXY: Rxyl_1723 Rxyl_1727
            SSM: Spirs_1664 Spirs_2579 Spirs_2985 Spirs_2990
            SUS: Acid_1485 Acid_4014
            DFE: Dfer_5698
            LBY: Lbys_0019
            STR: Sterm_4008 Sterm_4014
            IPO: Ilyop_2125
            AVA: Ava_0798
            TRA: Trad_1231 Trad_1233
            MRB: Mrub_1694 Mrub_1699
            MSV: Mesil_0994
            TMA: TM0414
            TPT: Tpet_0506
            TNA: CTN_0255
            TNP: Tnap_0206
            KOL: Kole_0987
            TTR: Tter_1523 Tter_1526
            CMA: Cmaq_0681
            TPE: Tpen_1013
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.18
            IUBMB Enzyme Nomenclature: 1.1.1.18
            ExPASy - ENZYME nomenclature database: 1.1.1.18
            BRENDA, the Enzyme Database: 1.1.1.18
            CAS: 9028-25-5
///
ENTRY       EC 1.1.1.19                 Enzyme
NAME        glucuronate reductase;
            aldehyde reductase;
            L-hexonate:NADP dehydrogenase;
            TPN-L-gulonate dehydrogenase;
            aldehyde reductase II;
            NADP-L-gulonate dehydrogenase;
            D-glucuronate dehydrogenase;
            D-glucuronate reductase;
            L-glucuronate reductase (incorrect)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-gulonate:NADP+ 6-oxidoreductase
REACTION    L-gulonate + NADP+ = D-glucuronate + NADPH + H+ [RN:R01481]
ALL_REAC    R01481
SUBSTRATE   L-gulonate [CPD:C00800];
            NADP+ [CPD:C00006]
PRODUCT     D-glucuronate [CPD:C00191];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also reduces D-galacturonate. May be identical with EC 1.1.1.2
            [alcohol dehydrogenase (NADP+)].
REFERENCE   1  [PMID:13913518]
  AUTHORS   SIVAK A, HOFFMANN-OSTENHOF O.
  TITLE     Enzymes of mesoinositol catabolism in the yeast Schwanniomyces
            accidentalis.
  JOURNAL   Biochim. Biophys. Acta. 53 (1961) 426-8.
  ORGANISM  Schwanniomyces occidentalis
REFERENCE   2
  AUTHORS   von Wartburg, J.P. and Wermoth, B.
  TITLE     Aldehyde reductase.
  JOURNAL   In: Jakoby, W.B. (Ed.), Enzymatic Basis of Detoxication, vol. 1,
            Academic Press, New York, 1980, p. 249-260.
REFERENCE   3  [PMID:13787380]
  AUTHORS   YORK JL, GROLLMAN AP, BUBLITZ C.
  TITLE     TPN-L-gluonate dehydrogenase.
  JOURNAL   Biochim. Biophys. Acta. 47 (1961) 298-306.
  ORGANISM  Rattus norvegicus [GN:rno], Sus scofa [GN:ssc]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec00053  Ascorbate and aldarate metabolism
            ec01100  Metabolic pathways
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.19
            IUBMB Enzyme Nomenclature: 1.1.1.19
            ExPASy - ENZYME nomenclature database: 1.1.1.19
            BRENDA, the Enzyme Database: 1.1.1.19
            CAS: 9028-29-9
///
ENTRY       EC 1.1.1.20                 Enzyme
NAME        glucuronolactone reductase;
            GRase;
            gulonolactone dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-gulono-1,4-lactone:NADP+ 1-oxidoreductase
REACTION    L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + NADPH + H+
            [RN:R03183]
ALL_REAC    R03183
SUBSTRATE   L-gulono-1,4-lactone [CPD:C01040];
            NADP+ [CPD:C00006]
PRODUCT     D-glucurono-3,6-lactone [CPD:C02670];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1
  AUTHORS   Suzuki, K., Mano, Y. and Shimazono, N.
  TITLE     Conversion of L-gulonolactone to L-ascorbic acid; properties of the
            microsomal enzyme in rat liver.
  JOURNAL   J. Biochem. (Tokyo) 48 (1960) 313-315.
PATHWAY     ec00053  Ascorbate and aldarate metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.20
            IUBMB Enzyme Nomenclature: 1.1.1.20
            ExPASy - ENZYME nomenclature database: 1.1.1.20
            BRENDA, the Enzyme Database: 1.1.1.20
            CAS: 9028-30-2
///
ENTRY       EC 1.1.1.21                 Enzyme
NAME        aldehyde reductase;
            aldose reductase;
            polyol dehydrogenase (NADP+);
            ALR2;
            alditol:NADP+ oxidoreductase;
            alditol:NADP+ 1-oxidoreductase;
            NADPH-aldopentose reductase;
            NADPH-aldose reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     alditol:NAD(P)+ 1-oxidoreductase
REACTION    alditol + NAD(P)+ = aldose + NAD(P)H + H+ [RN:R02819 R02820]
ALL_REAC    R02819 > R01036 R01093 R01758;
            R02820 > R01041 R01095 R01431 R01759 R01787;
            (other) R02531 R02577
SUBSTRATE   alditol [CPD:C00717];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     aldose [CPD:C01370];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
INHIBITOR   HOE-252 [CPD:C01426];
            Tolrestat [CPD:C01621];
            Zopolrestat [CPD:C01865];
            Salfredin [CPD:C05152]
COMMENT     Has wide specificity.
REFERENCE   1  [PMID:4216364]
  AUTHORS   Attwood MA, Doughty CC.
  TITLE     Purification and properties of calf liver aldose reductase.
  JOURNAL   Biochim. Biophys. Acta. 370 (1974) 358-68.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   2  [PMID:36151]
  AUTHORS   Boghosian RA, McGuinness ET.
  TITLE     Affinity purification and properties of porcine brain aldose
            reductase.
  JOURNAL   Biochim. Biophys. Acta. 567 (1979) 278-86.
  ORGANISM  Sus scofa [GN:ssc]
REFERENCE   3  [PMID:14401390]
  AUTHORS   HERS HG.
  TITLE     [Aldose reductase.]
  JOURNAL   Biochim. Biophys. Acta. 37 (1960) 120-6.
  ORGANISM  Rattus norvegicus [GN:rno]
REFERENCE   4  [PMID:4381350]
  AUTHORS   Scher BM, Horecker BL.
  TITLE     Pentose metabolism in Candida. 3. The triphosphopyridine
            nucleotide-specific polyol dehydrogenase of Candida utilis.
  JOURNAL   Arch. Biochem. Biophys. 116 (1966) 117-28.
  ORGANISM  Candida utilis
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec00051  Fructose and mannose metabolism
            ec00052  Galactose metabolism
            ec00561  Glycerolipid metabolism
            ec00620  Pyruvate metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K00011  aldehyde reductase
GENES       HSA: 231(AKR1B1)
            PTR: 737737(AKR1B1)
            PON: 100444840
            MCC: 705957(AKR1B1) 706406
            MMU: 100504386 11677(Akr1b3) 11997(Akr1b7) 14187(Akr1b8)
            RNO: 24192(Akr1b1)
            CFA: 482334
            AML: 100479370
            BTA: 317748(AKR1B1)
            SSC: 396816(ALR2)
            ECB: 100065145
            MDO: 100021757
            OAA: 100075884
            GGA: 418169(AKR1B10) 418170 418171(AKR1B1) 425137
            TGU: 100231722
            XLA: 398904(akr1b1)
            XTR: 496546(akr1b1)
            DRE: 553452(zgc:153855)
            BFO: BRAFLDRAFT_122465
            CIN: 100176226
            SPU: 589385
            DME: Dmel_CG10863 Dmel_CG12766 Dmel_CG6083 Dmel_CG6084 Dmel_CG9436
            DPO: Dpse_GA19342
            DAN: Dana_GF24531
            DER: Dere_GG13904
            DPE: Dper_GL22808
            DSE: Dsec_GM24729
            DSI: Dsim_GD12789
            DWI: Dwil_GK14636 Dwil_GK17015
            DYA: Dyak_GE20195
            DGR: Dgri_GH16631
            DMO: Dmoj_GI11589
            DVI: Dvir_GJ11267
            AGA: AgaP_AGAP011050
            AAG: AaeL_AAEL004088
            CQU: CpipJ_CPIJ003391
            AME: 551968
            NVI: 100120526(NV13783)
            TCA: 657943 658019 658097
            API: 100164695 100165768
            PHU: Phum_PHUM282300 Phum_PHUM335220
            ISC: IscW_ISCW002128
            CEL: Y39G8B.1
            CBR: CBG20740
            BMY: Bm1_43535
            SMM: Smp_053220.1
            SCE: YHR104W(GRE3)
            EHI: EHI_029620(466.t00004)
            TET: TTHERM_00697540 TTHERM_01051730 TTHERM_01080350 TTHERM_01080360
            TVA: TVAG_007830
            PAT: Patl_2877
            REH: H16_A3186
            RPA: RPA3161(yafB) RPA4297
            ABA: Acid345_2661
            SUS: Acid_2860
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.21
            IUBMB Enzyme Nomenclature: 1.1.1.21
            ExPASy - ENZYME nomenclature database: 1.1.1.21
            BRENDA, the Enzyme Database: 1.1.1.21
            CAS: 9028-31-3
///
ENTRY       EC 1.1.1.22                 Enzyme
NAME        UDP-glucose 6-dehydrogenase;
            UDP-glucose dehydrogenase;
            uridine diphosphoglucose dehydrogenase;
            UDPG dehydrogenase;
            UDPG:NAD oxidoreductase;
            UDP-alpha-D-glucose:NAD oxidoreductase;
            UDP-glucose:NAD+ oxidoreductase;
            uridine diphosphate glucose dehydrogenase;
            UDP-D-glucose dehydrogenase;
            uridine diphosphate D-glucose dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     UDP-glucose:NAD+ 6-oxidoreductase
REACTION    UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH + 2 H+
            [RN:R00286]
ALL_REAC    R00286
SUBSTRATE   UDP-glucose [CPD:C00029];
            NAD+ [CPD:C00003];
            H2O [CPD:C00001]
PRODUCT     UDP-glucuronate [CPD:C00167];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also acts on UDP-2-deoxyglucose.
REFERENCE   1  [PMID:1091296]
  AUTHORS   Druzhinina TN, Kusov YY, Shibaev VN, Kochetkov NK, Biely P, Kucar S,
            Bauer S.
  TITLE     Uridine diphosphate 2-deoxyglucose. Chemical synthesis, enzymic
            oxidation and epimerization.
  JOURNAL   Biochim. Biophys. Acta. 381 (1975) 301-7.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   2  [PMID:13373402]
  AUTHORS   KALCKAR HM, MAXWELL ES, STROMINGER JL.
  TITLE     Some properties of uridine diphosphoglucose dehydrogenase.
  JOURNAL   Arch. Biochem. Biophys. 65 (1956) 2-10.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   3  [PMID:13459898]
  AUTHORS   STROMINGER JL, MAPSON LW.
  TITLE     Uridine diphosphoglucose dehydrogenase of pea seedlings.
  JOURNAL   Biochem. J. 66 (1957) 567-72.
  ORGANISM  Pisum sativum
REFERENCE   4  [PMID:13398389]
  AUTHORS   AXELROD J, KALCKAR HM, MAXWELL ES, STROMINGER JL.
  TITLE     Enzymatic formation of uridine diphosphoglucuronic acid.
  JOURNAL   J. Biol. Chem. 224 (1957) 79-90.
  ORGANISM  Bos taurus [GN:bta]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec00053  Ascorbate and aldarate metabolism
            ec00500  Starch and sucrose metabolism
            ec00520  Amino sugar and nucleotide sugar metabolism
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00012  UDPglucose 6-dehydrogenase
GENES       HSA: 7358(UGDH)
            PTR: 471171(UGDH)
            PON: 100174620(UGDH)
            MCC: 699500(UGDH)
            MMU: 22235(Ugdh)
            RNO: 83472(Ugdh)
            CFA: 479107(UGDH)
            AML: 100466428(UGDH)
            BTA: 281564(UGDH)
            ECB: 100055067(UGDH)
            MDO: 100016058
            OAA: 100078689(UGDH)
            GGA: 422792(UGDH) 771129
            TGU: 100217939
            XLA: 379152(ugdh-b) 734199(ugdh-a)
            XTR: 541452(ugdh)
            DRE: 116991(ugdh)
            BFO: BRAFLDRAFT_126506
            CIN: 100178373(ugdh)
            SPU: 579664
            DME: Dmel_CG10072(sgl)
            DPO: Dpse_GA10050
            DAN: Dana_GF10882
            DER: Dere_GG15016
            DPE: Dper_GL15063
            DSE: Dsec_GM13805
            DSI: Dsim_GD13103
            DWI: Dwil_GK17198
            DYA: Dyak_GE20458
            DGR: Dgri_GH16103
            DMO: Dmoj_GI12367
            DVI: Dvir_GJ12259
            AGA: AgaP_AGAP006532
            AAG: AaeL_AAEL011242
            CQU: CpipJ_CPIJ002992
            AME: 413356
            NVI: 100114791(NV17389)
            TCA: 659908
            API: 100167376
            PHU: Phum_PHUM527160
            ISC: IscW_ISCW009911
            CEL: F29F11.1(sqv-4)
            CBR: CBG09668(Cbr-sqv-4)
            BMY: Bm1_47645
            SMM: Smp_084830
            NVE: NEMVE_v1g191320
            HMG: 100208824
            TAD: TRIADDRAFT_57391
            ATH: AT1G26570(UGD1) AT3G29360 AT5G15490 AT5G39320
            POP: POPTR_566943 POPTR_832653 POPTR_835719
            RCU: RCOM_1470440 RCOM_1621050 RCOM_1621090 RCOM_1621100
            VVI: 100261061 100264653
            OSA: 4333156 4333410 4334169 4352146 4352147
            SBI: SORBI_01g014970 SORBI_01g043150 SORBI_02g000970
            ZMA: 100279549(TIDP3299) 100282847(gpm540b) 100285497
            PPP: PHYPADRAFT_189559 PHYPADRAFT_208903 PHYPADRAFT_225811
                 PHYPADRAFT_226507
            CRE: CHLREDRAFT_185081(UGD2) CHLREDRAFT_205498(UGD1)
            VCN: VOLCADRAFT_107492 VOLCADRAFT_72551
            OLU: OSTLU_27143
            OTA: Ot13g01740
            CME: CMB031C CMT471C
            YLI: YALI0D02321g
            NCR: NCU04936 NCU08228
            PAN: PODANSg4717
            FGR: FG04232.1
            BFU: BC1G_03453
            ANI: AN9172.2
            AFM: AFUA_1G17020 AFUA_8G00920
            NFI: NFIA_008350 NFIA_094350
            AOR: AO090001000557 AO090005000972 AO090010000065
            ANG: An01g09820 An03g03480
            AFV: AFLA_082270 AFLA_116430
            ACT: ACLA_044720
            CNE: CNL06460
            CNB: CNBI0390
            LBC: LACBIDRAFT_317263
            MPR: MPER_11684
            CCI: CC1G_06970
            SCM: SCHCODRAFT_82564
            UMA: UM00118.1
            MGL: MGL_2955
            MBR: MONBRDRAFT_34909
            NGR: NAEGRDRAFT_58202 NAEGRDRAFT_61772
            CPV: cgd8_920
            CHO: Chro.80111
            TET: TTHERM_00494360
            PTM: GSPATT00025077001 GSPATT00036211001
            TCR: 509715.90 510105.100
            TVA: TVAG_114530
            PTI: PHATR_18745(UGDH1)
            TPS: THAPSDRAFT_42368(UGDH1)
            PIF: PITG_18375
            ECO: b2028(ugd)
            ECJ: JW2010(ugd)
            ECD: ECDH10B_2176(ugd)
            EBW: BWG_1819(ugd)
            ECE: Z3190(ugd)
            ECS: ECs2829
            ECF: ECH74115_2961(ugd)
            ETW: ECSP_2779(ugd)
            EOJ: ECO26_2939(ugd)
            EOI: ECO111_2754(ugd)
            EOH: ECO103_2507(ugd)
            ECG: E2348C_2169(ugd)
            EOK: G2583_2549(ugd)
            ECC: c2555(ugd)
            ECP: ECP_2071
            ECI: UTI89_C2301(ugd)
            ECV: APECO1_1125(ugd)
            ECX: EcHS_A2178(ugd)
            ECW: EcE24377A_2319(ugd)
            ECM: EcSMS35_1032(ugd)
            ECY: ECSE_2302
            ECR: ECIAI1_2108(ugd)
            ECQ: ECED1_2377(ugd)
            ECK: EC55989_2287(ugd)
            ECT: ECIAI39_0990(ugd)
            EUM: ECUMN_2370(ugd)
            ECZ: ECS88_2127(ugd)
            ECL: EcolC_1614
            EBR: ECB_01930(ugd)
            EBD: ECBD_1631
            EFE: EFER_2111(ugd)
            STY: STY2289(ugd)
            STT: t0793(ugd)
            STM: STM2080(udg)
            SPT: SPA0791(ugd)
            SEK: SSPA0741
            SPQ: SPAB_00953
            SEI: SPC_1632(ugd)
            SEC: SC2090(udg)
            SEH: SeHA_C2306
            SEE: SNSL254_A2259
            SEW: SeSA_A2308(ugd)
            SEA: SeAg_B2205
            SED: SeD_A2418
            SEG: SG2110(udg)
            SET: SEN2079(udg)
            SES: SARI_00804
            YPE: YPO2174
            YPK: y2147
            YPA: YPA_1532
            YPN: YPN_1641
            YPM: YP_1973(ugd)
            YPP: YPDSF_0960
            YPG: YpAngola_A2330
            YPZ: YPZ3_1671
            YPS: YPTB2100
            YPI: YpsIP31758_1968
            YPY: YPK_2077
            YPB: YPTS_2166
            YEN: YE2242
            SSN: SSON_2099(ugd)
            SBO: SBO_0857(ugd)
            SBC: SbBS512_E1203
            SDY: SDY_2213(ugd)
            ECA: ECA3147(ugd)
            PCT: PC1_2929
            PWA: Pecwa_1349
            ETA: ETA_15770(ugd)
            EPY: EpC_16460(ugd)
            EAM: EAMY_1961(ugd)
            EAY: EAM_1917
            EBI: EbC_24050(ugd)
            PLU: plu2500
            PAY: PAU_02026(ugd)
            WBR: WGLp368(ugd)
            SGL: SG1368
            ENT: Ent638_2641
            ENC: ECL_03349
            ESC: Entcl_1665
            ESA: ESA_01534
            CTU: Ctu_23880(udg)
            KPN: KPN_02493(ugd)
            KPE: KPK_1670(ugd)
            KPU: KP1_3701(ugd)
            KVA: Kvar_1563
            CKO: CKO_00757
            CRO: ROD_21661(ugd)
            SPE: Spro_2708
            PMR: PMI3189(ugd)
            EIC: NT01EI_1312
            ETR: ETAE_1202(ugd)
            HDE: HDEF_0538(ugd)
            DDA: Dd703_1202 Dd703_2679
            DDC: Dd586_1253
            DDD: Dda3937_03269(ugd)
            DZE: Dd1591_2849
            XBO: XBJ1_2434 XBJ1_4328(ugd)
            XNE: XNC1_2487
            PAM: PANA_2093(udg)
            PVA: Pvag_1536(ugd)
            PAO: Pat9b_2182
            PMU: PM0776
            ASU: Asuc_0055
            AAP: NT05HA_1457
            AAT: D11S_2063
            XFA: XF1606
            XFT: PD1167(ugd)
            XFM: Xfasm12_1276
            XFN: XfasM23_1244
            XCC: XCC1503(ugd)
            XCB: XC_2733
            XCA: xccb100_2769(ugd)
            XCV: XCV1594(ugd1) XCV3705(ugd2)
            XAC: XAC1551(ugd) XAC3581(ugd)
            XOO: XOO2066(ugd)
            XOM: XOO_1946
            XOP: PXO_01224
            XAL: XALc_1655(ugd)
            SML: Smlt3181
            SMT: Smal_2616
            PSU: Psesu_2997
            VCH: VCA0780
            VCO: VC0395_0720(ugd)
            VCM: VCM66_A0739(ugd)
            VCJ: VCD_000542
            VVU: VV1_0774
            VVY: VV0365
            VVM: VVM_04345
            VPA: VP0236
            VHA: VIBHAR_00706
            VEX: VEA_001761
            VFM: VFMJ11_0190
            PPR: PBPRA2657 PBPRA2675
            PAE: PA2022 PA3559
            PAU: PA14_18300 PA14_38360(ugd)
            PAP: PSPA7_1586 PSPA7_3266
            PAG: PLES_14741 PLES_33011
            PPU: PP_2926
            PPF: Pput_2766
            PPG: PputGB1_2846
            PPW: PputW619_3190
            PST: PSPTO_2891 PSPTO_5585
            PSB: Psyr_2696 Psyr_5105
            PSP: PSPPH_2809
            PFL: PFL_3050(udg) PFL_3078
            PFO: Pfl01_2024 Pfl01_2817 Pfl01_2848 Pfl01_4070
            PFS: PFLU3036 PFLU3676(udg)
            PEN: PSEEN3359
            PMY: Pmen_2354
            CJA: CJA_3434
            AVN: Avin_12150 Avin_27790
            PAR: Psyc_0110
            PCR: Pcryo_0119
            PRW: PsycPRwf_0273 PsycPRwf_0275
            ACI: ACIAD0072(ugd) ACIAD0100
            ACD: AOLE_19065
            ACB: A1S_0063
            ABM: ABSDF0080
            ABY: ABAYE3802
            ABC: ACICU_00089
            ABN: AB57_0112
            ABB: ABBFA_003448
            MCT: MCR_1807(ugd)
            SON: SO_4687(ugd)
            SFR: Sfri_1373
            SAZ: Sama_2236
            SBL: Sbal_0071
            SBM: Shew185_4328
            SBN: Sbal195_3019 Sbal195_4468
            SBP: Sbal223_4273
            SSE: Ssed_0919
            SPL: Spea_1418
            SHE: Shewmr4_1330 Shewmr4_3885
            SHM: Shewmr7_3978
            SHN: Shewana3_1387 Shewana3_4088
            SHW: Sputw3181_0063
            SHL: Shal_1501
            SVO: SVI_1495(ugd)
            ILO: IL0538(ugd)
            CPS: CPS_0591(ugd)
            PHA: PSHAa0444(ugd)
            PAT: Patl_3200
            SDE: Sde_2115
            MAQ: Maqu_1710
            AMC: MADE_00992
            TTU: TERTU_1418
            FBL: Fbal_0147 Fbal_0443 Fbal_1087
            CBU: CBU_0680 CBU_0846(ugd)
            CBS: COXBURSA331_A0798 COXBURSA331_A1104(ugd)
            CBD: CBUD_0693 CBUD_0911(ugd)
            CBG: CbuG_1155(ugd) CbuG_1323
            CBC: CbuK_0714(ugd) CbuK_1575
            LLO: LLO_3155(ugd)
            MCA: MCA2487(ugd)
            TCX: Tcr_0609 Tcr_1510
            NOC: Noc_2015
            NHL: Nhal_3283
            NWA: Nwat_1086
            ALV: Alvin_2378
            AEH: Mlg_0289
            HHA: Hhal_2178
            TGR: Tgr7_2339
            TKM: TK90_1572
            HNA: Hneap_1236
            HCH: HCH_04682(ugd) HCH_04938
            CSA: Csal_1761 Csal_1860
            HEL: HELO_2329(ugd) HELO_2573(ugd2)
            ABO: ABO_0932(ugd1) ABO_0935(ugd2)
            MMW: Mmwyl1_0800 Mmwyl1_3483
            AHA: AHA_0993 AHA_2880
            ASA: ASA_3306(ugd)
            TAU: Tola_2842
            AFE: Lferr_0769
            AFR: AFE_0618 AFE_1343 AFE_1405
            GPB: HDN1F_10520(ugd)
            CVI: CV_3041(ugd)
            RSO: RSc0913(ugd)
            RSC: RCFBP_20568(ugd)
            RSL: RPSI07_2471(ugd)
            RPI: Rpic_0783
            RPF: Rpic12D_0578 Rpic12D_0854
            REU: Reut_A2565
            REH: H16_A0802(ugd)
            RME: Rmet_0726
            CTI: RALTA_A0783(ugd)
            BMA: BMA0423(ugd)
            BMV: BMASAVP1_A2567(ugd)
            BML: BMA10229_A0942(ugd)
            BMN: BMA10247_0206(ugd)
            BPS: BPSL2511(udg) BPSS1833(udg2)
            BPM: BURPS1710b_2988(udg) BURPS1710b_A0917(udg2)
            BPL: BURPS1106A_2941(udg) BURPS1106A_A2484(udg)
            BPD: BURPS668_2878(udg) BURPS668_A2622(udg)
            BPR: GBP346_A3058
            BTE: BTH_I1642 BTH_II0544
            BVI: Bcep1808_0972 Bcep1808_4202 Bcep1808_6511
            BUR: Bcep18194_A4164 Bcep18194_B0866 Bcep18194_B2275
            BCN: Bcen_0572 Bcen_4542
            BCH: Bcen2424_1051 Bcen2424_3821
            BCM: Bcenmc03_1010 Bcenmc03_3703
            BCJ: BCAL2946(udg) BCAM0855(bceC) BCAM2034
            BAM: Bamb_0927 Bamb_5547
            BAC: BamMC406_0931 BamMC406_3724
            BMU: Bmul_2253 Bmul_3767 Bmul_4918
            BMJ: BMULJ_00986(ugd) BMULJ_03596(ugd) BMULJ_04749(ugd)
            BXE: Bxe_A0986 Bxe_A2245 Bxe_C1072
            BPH: Bphy_0750 Bphy_1058
            BPY: Bphyt_1956 Bphyt_2997
            BGL: bglu_1g08840 bglu_2g16520
            BGE: BC1002_1501 BC1002_2227
            BRH: RBRH_01721
            PNU: Pnuc_0503
            PNE: Pnec_1305
            BPE: BP3728(rkpK)
            BPA: BPP4227(rkpK)
            BBR: BB4815(rkpK)
            BPT: Bpet0183(ugd)
            BAV: BAV3273(rkpK)
            AXY: AXYL_00231(ugd)
            AJS: Ajs_0408
            DIA: Dtpsy_0400
            VPE: Varpa_3050 Varpa_5657
            CTT: CtCNB1_0107 CtCNB1_2758
            ADN: Alide_0481
            MPT: Mpe_A0606
            HSE: Hsero_2003(ugd) Hsero_3685(ugdH)
            LCH: Lcho_2323
            TIN: Tint_1149
            NEU: NE1343(udg)
            NET: Neut_1093
            EBA: ebA899(ugd)
            AZO: azo1076(ugd) azo2232(udgH)
            DAR: Daro_1284
            TMZ: Tmz1t_1121 Tmz1t_1858
            TBD: Tbd_0961
            MMB: Mmol_1785
            MEI: Msip34_1725 Msip34_1812
            MEP: MPQ_1725(ugd)
            APP: CAP2UW1_3291
            SLT: Slit_1377
            GCA: Galf_1166
            HHE: HH0644(kfiD)
            WSU: WS0583
            TDN: Suden_1968
            SKU: Sulku_2135
            CJE: Cj1441c(kfiD)
            CJU: C8J_1345
            CJN: ICDCCJ_1372
            CFF: CFF8240_1388
            CCV: CCV52592_1223
            CCO: CCC13826_0463
            ABU: Abu_0659(ugd)
            ANT: Arnit_2574
            SDL: Sdel_1795
            NIS: NIS_0741
            NAM: NAMH_1674
            GSU: GSU1816(ugd)
            GME: Gmet_1430
            GUR: Gura_2308
            GLO: Glov_1142
            GBM: Gbem_2287(ugd)
            GEO: Geob_2929
            GEM: GM21_1936
            PCA: Pcar_1466(ugd) Pcar_1806
            PPD: Ppro_1022
            DVU: DVU1907(ugd)
            DVL: Dvul_1257
            DVM: DvMF_0282
            DDE: Dde_2042
            DDS: Ddes_1145
            DMA: DMR_27530(rkpK)
            DSA: Desal_1991
            DAS: Daes_1737
            LIP: LI0730(ugd)
            DBA: Dbac_1843
            DRT: Dret_1693
            DPS: DP0014 DPPB70
            DAK: DaAHT2_1793 DaAHT2_1833
            DPR: Despr_2195
            DOL: Dole_1279
            DAL: Dalk_1701
            DAT: HRM2_29740(ugd)
            ADE: Adeh_1057 Adeh_4305
            ACP: A2cp1_1185 A2cp1_4460
            AFW: Anae109_3213 Anae109_4447
            ANK: AnaeK_1116 AnaeK_4441
            MXA: MXAN_1048
            SCL: sce2793(rkpK)
            HOH: Hoch_6075
            SAT: SYN_00532
            SFU: Sfum_3370
            DBR: Deba_2080
            RPR: RP779
            RTY: RT0766(udg)
            RCM: A1E_04980
            RCO: RC1212(udg)
            RFE: RF_1245(udg)
            RAK: A1C_06055
            RRI: A1G_06645
            RRJ: RrIowa_1420
            RMS: RMA_1229(udg)
            RPK: RPR_04805
            RAF: RAF_ORF1104(udg)
            RBE: RBE_0075(udg)
            RBO: A1I_07570
            WOL: WD0620
            WRI: WRi_005820
            PUB: SAR11_1086(ugd)
            MLO: mlr5265
            MCI: Mesci_0237
            MES: Meso_0484 Meso_2782
            PLA: Plav_1921
            SME: SMc02641(rkpK)
            SMD: Smed_0688
            RHI: NGR_c08370(ugdH)
            ATU: Atu4149(ugdH)
            ARA: Arad_3519(rkpK) Arad_7616(rkpK)
            AVI: Avi_1502(ugdH)
            RET: RHE_CH03238(rkpK)
            REC: RHECIAT_CH0003478(rkpK)
            RLE: RL3667
            RLT: Rleg2_2987
            RLG: Rleg_3235
            BME: BMEII0727
            BMI: BMEA_B0518
            BMF: BAB2_0692(ugd)
            BMB: BruAb2_0677(ugd)
            BMC: BAbS19_II06470
            BMS: BRA0545(ugd)
            BMT: BSUIS_B0541
            BOV: BOV_A0476(ugd)
            BCS: BCAN_B0544
            BMR: BMI_II539(ugd)
            OAN: Oant_1714 Oant_4414
            BJA: bll8129(ugdH) blr2383(ugdH)
            BRA: BRADO0754(rkpK)
            BBT: BBta_7353(rkpK)
            RPA: RPA4018
            RPB: RPB_1585
            RPC: RPC_4156
            RPD: RPD_1593
            RPE: RPE_1120 RPE_1513 RPE_3505 RPE_4206
            RPT: Rpal_4548
            RPX: Rpdx1_4277
            NWI: Nwi_0543 Nwi_2380
            NHA: Nham_1057 Nham_2755
            OCA: OCAR_6122 OCAR_7565
            XAU: Xaut_3551
            AZC: AZC_2260
            SNO: Snov_0558 Snov_3337
            MEX: Mext_1948 Mext_3028 Mext_3681
            MEA: Mex_1p1822(ugdH) Mex_1p3235(ugdH)
            MDI: METDI2710(ugdH) METDI3800(ugdH)
            MRD: Mrad2831_0953 Mrad2831_4606
            MET: M446_5192
            MPO: Mpop_1839 Mpop_3217
            MCH: Mchl_2224 Mchl_3252
            MNO: Mnod_0775 Mnod_1947
            BID: Bind_0795 Bind_2639
            MSL: Msil_2329
            HDN: Hden_3055
            RVA: Rvan_2278
            CCR: CC_2379 CC_2382
            CCS: CCNA_02464 CCNA_02465
            CAK: Caul_4824
            CSE: Cseg_0087 Cseg_0502
            PZU: PHZ_c2961(ugd)
            BSB: Bresu_2964
            AEX: Astex_2223
            SIT: TM1040_3775
            RSP: RSP_0653
            RSH: Rsph17029_2306
            RSQ: Rsph17025_0579 Rsph17025_4098
            RSK: RSKD131_2010
            RCP: RCAP_rcc01383(ugd)
            JAN: Jann_0076
            RDE: RD1_B0057(ugd)
            DSH: Dshi_3861
            MMR: Mmar10_2489
            HNE: HNE_3236
            HBA: Hbal_3189
            ZMO: ZMO0819
            ZMN: Za10_0469
            NAR: Saro_3255
            SAL: Sala_1563
            SWI: Swit_4534
            SJP: SJA_C1-19330(ugd) SJA_C1-22200(ugd)
            ELI: ELI_01215
            GOX: GOX0924
            GBE: GbCGDNIH1_2221
            ACR: Acry_0210 Acry_1348
            GDI: GDI_1140 GDI_2545(ugd)
            GDJ: Gdia_0785 Gdia_1853
            APT: APA01_17690
            RRU: Rru_A2116
            RCE: RC1_1698(rkpK)
            MAG: amb0576
            AZL: AZL_d00320(ugd)
            PBR: PB2503_09164
            APB: SAR116_1673
            MGM: Mmc1_0333
            DIN: Selin_0716
            BSU: BSU30860(ytcA) BSU35580(tuaD) BSU36230(ywqF)
            BSS: BSUW23_14980(ytcA) BSUW23_17445(tuaD) BSUW23_17825(ywqF)
            BHA: BH3708
            BAN: BA_5434(ugd)
            BAR: GBAA_5434(ugd) GBAA_pXO1_0130(ugd)
            BAT: BAS5049
            BAH: BAMEG_5484(ugd) BAMEG_A0123
            BAI: BAA_5462(ugd) BAA_A0129
            BAL: BACI_c51860(ugd) BACI_pCIXO101150
            BCE: BC5202
            BCA: BCE_5308(ugd) BCE_5385(ugd)
            BCZ: BCZK4894(ugd)
            BCR: BCAH187_A5366(ugd)
            BCB: BCB4264_A5321(ugd)
            BCU: BCAH820_5290(ugd)
            BCG: BCG9842_B5638(ugd)
            BCQ: BCQ_5022(ugd)
            BCX: BCA_5330(ugd) BCA_5413 BCA_A0114
            BCY: Bcer98_2076
            BTK: BT9727_4879(ugd)
            BTL: BALH_4694(ugd) BALH_4773(ugd)
            BTB: BMB171_C4793(ugd)
            BWE: BcerKBAB4_4994 BcerKBAB4_5066 BcerKBAB4_5424
            BLI: BL03352(tuaD)
            BLD: BLi03804(tuaD)
            BAY: RBAM_032730(tuaD) RBAM_033450(ywqF)
            BAO: BAMF_3399(tuaD) BAMF_3467(ywqF)
            BAE: BATR1942_15685 BATR1942_16035
            BCL: ABC3167 ABC3686
            BPU: BPUM_3208(tuaD) BPUM_3276(ywqF)
            BPF: BpOF4_06530(ugd)
            BMQ: BMQ_1118(tuaD)
            BMD: BMD_1122
            BSE: Bsel_3032 Bsel_3035
            BCO: Bcell_3719
            OIH: OB2884 OB2929
            GKA: GK0840 GK3254
            GTN: GTNG_0722
            GWC: GWCH70_3180
            GYC: GYMC61_1642 GYMC61_3344
            GYA: GYMC52_0766 GYMC52_3375
            GCT: GC56T3_2704 GC56T3_3257 GC56T3_3298
            GMC: GY4MC1_1977 GY4MC1_3634
            AFL: Aflv_2095 Aflv_2667
            SSP: SSP0068
            ESI: Exig_2624 Exig_2651
            EAT: EAT1b_1174
            BBE: BBR47_25230(ywqF)
            PJD: Pjdr2_0365 Pjdr2_0414 Pjdr2_5490
            PPY: PPE_01134 PPE_01150
            PPM: PPSC2_c1213 PPSC2_c1230
            LLM: llmg_1616(ugd)
            SPY: SPy_0542 SPy_2201(hasB)
            SPZ: M5005_Spy_0449 M5005_Spy_1852(hasB)
            SPM: spyM18_0608 spyM18_2237(hasB)
            SPG: SpyM3_0385 SpyM3_1852(hasB)
            SPS: SPs1468 SPs1848
            SPH: MGAS10270_Spy0450 MGAS10270_Spy1971(hasB) MGAS10270_Spy1972
            SPI: MGAS10750_Spy0469(hasB)
            SPJ: MGAS2096_Spy0468 MGAS2096_Spy1883(hasB)
            SPK: MGAS9429_Spy0448 MGAS9429_Spy1863(hasB)
            SPF: SpyM51415 SpyM51825(hasB)
            SPA: M6_Spy0483 M6_Spy1870
            SPB: M28_Spy0437 M28_Spy1885(hasB)
            SOZ: Spy49_0459 Spy49_1806(hasB)
            SPD: SPD_0143 SPD_0326(cps2K)
            SPR: spr0139(ugd) spr0318(cps2K)
            SPW: SPCG_0142(ugd)
            SPX: SPG_0142
            SNE: SPN23F_01500(ugd)
            SPV: SPH_0252
            SNM: SP70585_0425(ugd)
            SJJ: SPJ_0170
            SPP: SPP_0210 SPP_0393
            SNC: HMPREF0837_10450(udg)
            SNB: SP670_0220(ugd)
            SNP: SPAP_0204
            STE: STER_0150
            SEQ: SZO_01710
            SEZ: Sez_0200(hasB)
            SEU: SEQ_0270
            SUB: SUB1027(hasB2) SUB1696(hasB1)
            LSL: LSL_0979(ugd)
            OOE: OEOE_1737
            CPE: CPE0494
            CTH: Cthe_1352
            CDF: CD2771(rkpK)
            CDC: CD196_2612(rkpK)
            CDL: CDR20291_2659(rkpK)
            CBE: Cbei_4738
            CKL: CKL_2099(rkpK)
            CKR: CKR_1838
            CPY: Cphy_1210
            STH: STH785
            SWO: Swol_0617
            VPR: Vpar_0683
            AFN: Acfer_0499 Acfer_0569
            DSY: DSY2447
            DHD: Dhaf_3605
            DRM: Dred_3027
            DAE: Dtox_2846 Dtox_4079 Dtox_4084
            APR: Apre_1256
            ELM: ELI_1796 ELI_4123
            BPB: bpr_I0828
            EHA: Ethha_0653
            RAL: Rumal_0413
            TMR: Tmar_0717
            TEX: Teth514_2277
            CKI: Calkr_2446
            TOC: Toce_0502
            CPO: COPRO5265_0430
            NTH: Nther_1581 Nther_2536
            HOR: Hore_22770
            HAS: Halsa_2338
            AAR: Acear_2158
            MMO: MMOB6010(udgA)
            MTU: Rv0322(udgA)
            MTC: MT0337(ugdA)
            MRA: MRA_0331(udgA)
            MTF: TBFG_10327
            MTB: TBMG_00326(TBMG_00326.1)
            MBO: Mb0330(udgA)
            MBB: BCG_0362(udgA)
            MBT: JTY_0332(udgA)
            MPA: MAP3825(udgA)
            MAV: MAV_4092 MAV_4823
            MSM: MSMEG_0680 MSMEG_5982
            MVA: Mvan_0598
            MGI: Mflv_0289
            MAB: MAB_4295c
            MMC: Mmcs_0931 Mmcs_3113
            MKM: Mkms_0948 Mkms_3173
            MJL: Mjls_0966
            MSP: Mspyr1_04850
            MMI: MMAR_0603(udgA)
            CGL: NCgl0351(cgl0360) NCgl2750(cgl2847)
            CGB: cg0435(udgA1) cg3154(udgA2)
            CGT: cgR_0673 cgR_2736
            CEF: CE2662
            CDI: DIP2141
            CJK: jk0173(udgA)
            CUR: cur_1836
            CAR: cauri_2345(udgA)
            CKP: ckrop_0269
            CPU: cpfrc_01934(udgA)
            NFA: nfa54240(ugd)
            RHA: RHA1_ro05446 RHA1_ro05455
            RER: RER_13140(udg) RER_13260(udg) RER_13290(udg)
            ROP: ROP_55130(udg) ROP_55250(udg)
            REQ: REQ_25580 REQ_40650
            GBR: Gbro_4346
            TPR: Tpau_2984
            SRT: Srot_1228
            SCO: SCO3052(SCBAC19G2.07)
            SMA: SAV_5025(udgA)
            SGR: SGR_4481
            SCB: SCAB_40291 SCAB_54911
            LXX: Lxx03520(udgA)
            CMI: CMM_1429(udgA)
            CMS: CMS_1524
            ART: Arth_1069 Arth_3207
            AAU: AAur_1182 AAur_3170 AAur_4110
            ACH: Achl_1159
            AAI: AARI_23120
            RSA: RSal33209_2984
            KRH: KRH_12660(rkpK)
            MLU: Mlut_08720
            BCV: Bcav_1006 Bcav_1163
            BFA: Bfae_02040
            JDE: Jden_0034
            KSE: Ksed_26860
            XCE: Xcel_2850
            SKE: Sked_28520
            CFL: Cfla_3192
            ICA: Intca_1205
            PAC: PPA0593
            PAK: HMPREF0675_3654
            PFR: PFREUD_02540(udgA)
            NCA: Noca_4579
            KFL: Kfla_1451
            TFU: Tfu_2544
            NDA: Ndas_3879
            TCU: Tcur_2901
            SRO: Sros_1344
            FRA: Francci3_0709 Francci3_3549
            FRE: Franean1_5905 Franean1_6546 Franean1_6677 Franean1_7280
            FRI: FraEuI1c_0159 FraEuI1c_0590 FraEuI1c_6112
            FAL: FRAAL1223(ugd) FRAAL5745(udgA)
            ACE: Acel_0408
            NML: Namu_4461
            GOB: Gobs_0421 Gobs_0912
            KRA: Krad_3900
            SEN: SACE_0095(rkpK) SACE_5565(rkpK) SACE_5566
            SVI: Svir_11200
            TBI: Tbis_0713
            AMD: AMED_0105(ugd) AMED_4269(ugd)
            STP: Strop_0933 Strop_1504
            SAQ: Sare_0875
            MAU: Micau_0940
            MIL: ML5_1188
            CAI: Caci_7670
            SNA: Snas_5678
            BLN: Blon_2389
            BLL: BLJ_1891
            BLB: BBMN68_1501
            BLA: BLA_0593
            BLC: Balac_1388
            BLT: Balat_1388
            BDE: BDP_2033
            RXY: Rxyl_3115
            CWO: Cwoe_4614
            PCU: pc1695(rkpK)
            WCH: wcw_1168(ugd)
            SSM: Spirs_4274
            LIL: LA_1459(ugd)
            LIC: LIC12294(ugd)
            LBJ: LBJ_0959(ugd)
            LBL: LBL_2074(ugd)
            LBI: LEPBI_I0937(ugd)
            LBF: LBF_0904(ugd)
            BHY: BHWA1_02543(ugd)
            BRM: Bmur_0119
            BPO: BP951000_0339(ugd)
            ABA: Acid345_3497 Acid345_3806
            ACA: ACP_0750(tuaD)
            TSA: AciPR4_2176
            SUS: Acid_0622 Acid_6697 Acid_7497
            BTH: BT_0379 BT_0599 BT_0829 BT_1341
            BFR: BF1839 BF2297 BF3920
            BFS: BF1554 BF1904(wcfY) BF2386(rkpK)
            BVU: BVU_3154
            BHL: Bache_2331
            PGI: PG1143
            PGN: PGN_1243
            PDI: BDI_0441 BDI_1463 BDI_2215 BDI_3238 BDI_3822
            PPN: Palpr_0247 Palpr_0973
            APS: CFPG_595
            PRU: PRU_1313 PRU_1769
            PMZ: HMPREF0659_A5525
            SRU: SRU_0596 SRU_2709
            SRM: SRM_02917(udg)
            RMR: Rmar_1859
            CHU: CHU_0901(ugd) CHU_3394(ugd)
            DFE: Dfer_0064 Dfer_3001
            SLI: Slin_3526
            LBY: Lbys_0096
            MTT: Ftrac_1465 Ftrac_2666
            CPI: Cpin_1513 Cpin_2363
            PHE: Phep_3615
            GFO: GFO_2038
            FJO: Fjoh_0358
            FPS: FP1295(ugd)
            COC: Coch_0712
            RBI: RB2501_06660
            ZPR: ZPR_0543
            CAT: CA2559_13173
            RAN: Riean_1488
            FBC: FB2170_10026
            CAO: Celal_3146
            FBA: FIC_00331 FIC_02322
            FSU: Fisuc_0961 Fisuc_0997
            STR: Sterm_3094
            IPO: Ilyop_0397 Ilyop_2242
            OTE: Oter_2734
            CAA: Caka_1567
            MIN: Minf_0010(ugd)
            AMU: Amuc_1435
            GAU: GAU_2707(ugd)
            RBA: RB1784(ugdH)
            PSL: Psta_1357
            PLM: Plim_3736
            IPA: Isop_0060
            TAI: Taci_0276
            SYN: slr1299
            SYW: SYNW0199(Ugd)
            SYC: syc0570_d(ugd)
            SYF: Synpcc7942_0973
            SYD: Syncc9605_0190
            SYE: Syncc9902_0222
            SYG: sync_0233
            SYR: SynRCC307_0187(ugd)
            SYX: SynWH7803_0244(ugd)
            SYP: SYNPCC7002_A2340
            CYA: CYA_0485
            CYB: CYB_1930
            TEL: tll0664
            MAR: MAE_18150
            CYT: cce_3423(ugd)
            CYP: PCC8801_0894
            CYC: PCC7424_1850
            CYN: Cyan7425_3290
            CYH: Cyan8802_0920
            CYJ: Cyan7822_5295
            CYU: UCYN_11770
            GVI: gll0969 gll1798 gll2180 gll3719 glr1062
            ANA: alr0658
            NPU: Npun_R5160
            AVA: Ava_4589
            NAZ: Aazo_2628
            PMA: Pro1312(ugd)
            PMM: PMM1261(ugd)
            PMT: PMT1904(ugd)
            PMN: PMN2A_0062
            PMI: PMT9312_1312
            PMB: A9601_13901(ugd)
            PMC: P9515_14211(ugd)
            PMF: P9303_25391(ugd)
            PMG: P9301_13981(ugd)
            PMH: P9215_14111(ugd)
            PMJ: P9211_03421(ugd)
            PME: NATL1_06831(ugd)
            TER: Tery_2477
            AMR: AM1_2366(tuaD)
            CTE: CT1177
            CPC: Cpar_1724
            CCH: Cag_0821
            CPH: Cpha266_1534
            CPB: Cphamn1_1280
            CLI: Clim_1408
            PVI: Cvib_0945
            PLT: Plut_0956
            PPH: Ppha_1502
            PAA: Paes_1003
            CTS: Ctha_0204
            RRS: RoseRS_1617
            RCA: Rcas_3421
            CAU: Caur_2850
            CAG: Cagg_1110
            CHL: Chy400_3087
            HAU: Haur_3139
            TRO: trd_0813
            STI: Sthe_1193
            ATM: ANT_27250
            DGE: Dgeo_2649
            DMR: Deima_0155
            TRA: Trad_2856
            MSV: Mesil_2750
            AAE: aq_024(nsd)
            HYA: HY04AAS1_0500
            HTH: HTH_0366(nsd)
            TAL: Thal_1243
            SUL: SYO3AOP1_1498
            SAF: SULAZ_0327
            PMX: PERMA_1666
            TAM: Theam_0450
            TME: Tmel_1067
            TAF: THA_883
            DTH: DICTH_0556
            DTU: Dtur_0718
            TYE: THEYE_A0998
            NDE: NIDE2887(udg) NIDE4145(udg)
            TTR: Tter_0698 Tter_1130
            DDF: DEFDS_0115
            DAP: Dacet_2439
            CNI: Calni_2007
            MJA: MJ_1054
            MFE: Mefer_0525
            MVU: Metvu_0061
            MIF: Metin_1456
            MMQ: MmarC5_0495
            MMX: MmarC6_0603
            MMZ: MmarC7_1350
            MAE: Maeo_0414
            MVN: Mevan_0413
            MAC: MA4457
            MBA: Mbar_A1120
            MMA: MM_1132
            MBU: Mbur_1796
            MMH: Mmah_1928
            MEV: Metev_0052
            MTP: Mthe_0952 Mthe_1081
            MHU: Mhun_2113 Mhun_3078
            MEM: Memar_0207 Memar_0699
            MPI: Mpet_1016
            MBN: Mboo_1764
            MPD: MCP_2416(ugd)
            MST: Msp_0210
            MSI: Msm_1612
            MRU: mru_1051
            MFV: Mfer_0807
            AFU: AF0302(ugd-1) AF0596(ugd-2)
            APO: Arcpr_1218
            FPL: Ferp_2384
            HAL: VNG0046G(ugd) VNG1048G(udg1)
            HSL: OE1077R(ugd2) OE2524R(ugd1)
            HMA: rrnAC3239(ugd2)
            HWA: HQ2680A(ugd)
            NPH: NP2322A(ugd_2) NP4668A(ugd_1)
            HUT: Huta_1141
            HMU: Hmuk_1430
            HTU: Htur_2781
            NMG: Nmag_0917
            HVO: HVO_1531(aglM)
            HJE: HacjB3_03390
            HBO: Hbor_16990
            PAB: PAB0770(ugd)
            PFU: PF0771 PF1355
            TGA: TGAM_2146(algD)
            RCI: RCIX2404(ugd)
            SSO: SSO0810(ugd)
            SIS: LS215_1019
            SIA: M1425_0644
            SIM: M1627_0650
            SID: M164_0668
            SIN: YN1551_2332 YN1551_2405
            SII: LD85_1086
            MSE: Msed_1810
            PIS: Pisl_1505
            TPE: Tpen_1719
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.22
            IUBMB Enzyme Nomenclature: 1.1.1.22
            ExPASy - ENZYME nomenclature database: 1.1.1.22
            BRENDA, the Enzyme Database: 1.1.1.22
            CAS: 9028-26-6
///
ENTRY       EC 1.1.1.23                 Enzyme
NAME        histidinol dehydrogenase;
            L-histidinol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-histidinol:NAD+ oxidoreductase
REACTION    L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 3 H+
            [RN:R01158]
ALL_REAC    R01158;
            (other) R01163 R03012
SUBSTRATE   L-histidinol [CPD:C00860];
            NAD+ [CPD:C00003];
            H2O [CPD:C00001]
PRODUCT     L-histidine [CPD:C00135];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also oxidizes L-histidinal. The Neurospora enzyme also catalyses the
            reactions of EC 3.5.4.19 (phosphoribosyl-AMP cyclohydrolase) and EC
            3.6.1.31 (phosphoribosyl-ATP diphosphatase).
REFERENCE   1  [PMID:13192138]
  AUTHORS   ADAMS E.
  TITLE     The enzymatic synthesis of histidine from histidinol.
  JOURNAL   J. Biol. Chem. 209 (1954) 829-46.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   2  [PMID:13271397]
  AUTHORS   ADAMS E.
  TITLE     L-Histidinal, a biosynthetic precursor of histidine.
  JOURNAL   J. Biol. Chem. 217 (1955) 325-44.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   3  [PMID:4872177]
  AUTHORS   Yourno J, Ino I.
  TITLE     Purification and crystallization of histidinol dehydrogenase from
            Salmonella typhimurium LT-2.
  JOURNAL   J. Biol. Chem. 243 (1968) 3273-6.
  ORGANISM  Salmonella typhimurium [GN:stm]
REFERENCE   4  [PMID:4872176]
  AUTHORS   Loper JC.
  TITLE     Histidinol dehydrogenase from Salmonella typhimurium.
            Crystallization and composition studies.
  JOURNAL   J. Biol. Chem. 243 (1968) 3264-72.
  ORGANISM  Salmonella typhimurium [GN:stm]
PATHWAY     ec00340  Histidine metabolism
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00013  histidinol dehydrogenase
            K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP
                    cyclohydrolase / histidinol dehydrogenase
GENES       ATH: AT5G63890(ATHDH)
            RCU: RCOM_1045330
            VVI: 100253086
            OSA: 4324282
            PPP: PHYPADRAFT_145772
            CRE: CHLREDRAFT_126232(HDH1)
            OLU: OSTLU_13980
            CME: CMQ082C
            SCE: YCL030C(HIS4)
            AGO: AGOS_AFR703W
            KLA: KLLA0C01452g
            LTH: KLTH0F01430g
            PPA: PAS_chr1-4_0160
            VPO: Kpol_2002p40
            ZRO: ZYRO0F17578g
            CGR: CAGL0B00902g
            DHA: DEHA2F09086g
            PIC: PICST_89228(HIS2)
            PGU: PGUG_01505
            LEL: LELG_04328
            CAL: CaO19.13084(HIS4)
            CTP: CTRG_00122
            CDU: CD36_40210(HIS4)
            YLI: YALI0A15950g
            CLU: CLUG_05130
            NCR: NCU03139
            PAN: PODANSg5851
            MGR: MGG_01309(MG01309.4)
            FGR: FG00865.1
            SSL: SS1G_12269
            BFU: BC1G_01879
            ANI: AN0797.2 AN2723.2
            AFM: AFUA_1G14570 AFUA_1G17660
            NFI: NFIA_007520 NFIA_010850
            AOR: AO090003000477 AO090005000146
            ANG: An01g12570 An14g07210
            AFV: AFLA_033390 AFLA_073900
            ACT: ACLA_020860
            PCS: Pc16g14140
            CIM: CIMG_03310
            CPW: CPC735_008880
            URE: UREG_07141
            PNO: SNOG_07871 SNOG_11402
            TML: GSTUM_00010427001
            SPO: SPBC1711.13(his2)
            CNE: CND06120
            CNB: CNBD0280
            LBC: LACBIDRAFT_231720
            CCI: CC1G_00367
            SCM: SCHCODRAFT_71835
            UMA: UM03974.1
            MGL: MGL_2613
            MBR: MONBRDRAFT_29130
            PTI: PHATR_3140
            TPS: THAPSDRAFT_268256
            ECO: b2020(hisD)
            ECJ: JW2002(hisD)
            ECD: ECDH10B_2168(hisD)
            EBW: BWG_1811(hisD)
            ECE: Z3182(hisD)
            ECS: ECs2821(hisD)
            ECF: ECH74115_2953(hisD)
            ETW: ECSP_2771(hisD)
            EOJ: ECO26_2931(hisD)
            EOI: ECO111_2744(hisD)
            EOH: ECO103_2499(hisD)
            ECG: E2348C_2161(hisD)
            EOK: G2583_2541(hisD)
            ECC: c2547(hisD)
            ECP: ECP_2063(hisD)
            ECI: UTI89_C2293(hisD)
            ECV: APECO1_1117(hisD)
            ECX: EcHS_A2159(hisD)
            ECW: EcE24377A_2311(hisD)
            ECM: EcSMS35_1040(hisD)
            ECY: ECSE_2294(hisD)
            ECR: ECIAI1_2090(hisD)
            ECQ: ECED1_2369(hisD)
            ECK: EC55989_2279(hisD)
            ECT: ECIAI39_0998(hisD)
            EUM: ECUMN_2362(hisD)
            ECZ: ECS88_2119(hisD)
            ECL: EcolC_1622(hisD)
            EBR: ECB_01922(hisD)
            EBD: ECBD_1639(hisD)
            EFE: EFER_2103(hisD)
            STY: STY2281(hisD)
            STT: t0801(hisD)
            STM: STM2072(hisD)
            SPT: SPA0799(hisD)
            SEK: SSPA0749(hisD)
            SPQ: SPAB_00961(hisD)
            SEI: SPC_1640(hisD)
            SEC: SC2082(hisD)
            SEH: SeHA_C2298(hisD)
            SEE: SNSL254_A2251(hisD)
            SEW: SeSA_A2300(hisD)
            SEA: SeAg_B2197(hisD)
            SED: SeD_A2410(hisD)
            SEG: SG2102(hisD)
            SET: SEN2071(hisD)
            SES: SARI_00812(hisD)
            YPE: YPO1548(hisD)
            YPK: y2621(hisD)
            YPA: YPA_0844(hisD)
            YPN: YPN_2431(hisD)
            YPM: YP_1437(hisD)
            YPP: YPDSF_1428(hisD)
            YPG: YpAngola_A3170(hisD)
            YPZ: YPZ3_1413(hisD)
            YPS: YPTB1561(hisD)
            YPI: YpsIP31758_2429(hisD)
            YPY: YPK_2526(hisD)
            YPB: YPTS_1670(hisD)
            YEN: YE2766(hisD)
            SFL: SF2082(hisD)
            SFX: S2203(hisD)
            SFV: SFV_2080(hisD)
            SSN: SSON_2091(hisD)
            SBO: SBO_0846(hisD)
            SBC: SbBS512_E1212(hisD)
            SDY: SDY_2221(hisD)
            ECA: ECA2583(hisD)
            PCT: PC1_1744
            PWA: Pecwa_2011(hisD)
            ETA: ETA_13550(hisD)
            EPY: EpC_14190(hisD)
            EAM: EAMY_2221(hisD)
            EAY: EAM_2142(hisD)
            EBI: EbC_29100(hisD)
            PLU: plu1569(hisD)
            PAY: PAU_02874(hisCD)
            BUC: BU100(hisD)
            BAS: BUsg093(hisD)
            BAB: bbp094(hisD)
            BCC: BCc_064(hisD)
            BAP: BUAP5A_098(hisD)
            BAU: BUAPTUC7_099(hisD)
            SGL: SG1129(hisD)
            ENT: Ent638_2632(hisD)
            ENC: ECL_03340
            ESC: Entcl_1673
            ESA: ESA_01197(hisD)
            CTU: Ctu_27170(hisD)
            KPN: KPN_02476(hisD)
            KPE: KPK_1689(hisD)
            KPU: KP1_3680(hisD)
            KVA: Kvar_1579
            CKO: CKO_00765(hisD)
            CRO: ROD_21581(hisD)
            SPE: Spro_1615(hisD)
            PMR: PMI0664(hisD)
            EIC: NT01EI_2565
            ETR: ETAE_2276(hisD)
            BFL: Bfl463(hisD)
            BPN: BPEN_478(hisD)
            BVA: BVAF_464(hisD)
            DDA: Dd703_2228
            DDC: Dd586_2270
            DDD: Dda3937_02973(hisD)
            DZE: Dd1591_2330
            XBO: XBJ1_0917(hisD)
            XNE: XNC1_1519(hisD)
            PAM: PANA_2468(hisD)
            PVA: Pvag_1952(hisD)
            PAO: Pat9b_2563 Pat9b_4925
            HIN: HI0469(hisD)
            HIT: NTHI0600(hisD)
            HIP: CGSHiEE_00645(hisD)
            HIQ: CGSHiGG_05590(hisD)
            HIF: HIBPF18600
            HIL: HICON_09450
            PMU: PM1198(hisD)
            MSU: MS1892(hisD)
            APL: APL_2020(hisD)
            APJ: APJL_2070(hisD)
            APA: APP7_2107(hisD)
            ASU: Asuc_0631(hisD)
            AAP: NT05HA_1776(hisD)
            XFA: XF2219(hisD)
            XFT: PD1267(hisD)
            XFM: Xfasm12_1419(hisD)
            XFN: XfasM23_1352(hisD)
            XCC: XCC1809(hisD)
            XCB: XC_2380(hisD)
            XCA: xccb100_2096(hisD)
            XCV: XCV1875(hisD)
            XAC: XAC1829(hisD)
            XOO: XOO2256(hisD)
            XOM: XOO_2119(hisD)
            XOP: PXO_00833(hisD)
            XAL: XALc_1254(hisD)
            SML: Smlt2163(hisD)
            SMT: Smal_1757(hisD)
            PSU: Psesu_1819
            VCH: VC1133(hisD)
            VCO: VC0395_A0703(hisD)
            VCM: VCM66_1089(hisD)
            VCJ: VCD_003209(hisD)
            VVU: VV1_2919(hisD)
            VVY: VV1351(hisD)
            VVM: VVM_03445
            VPA: VP1138(hisD)
            VHA: VIBHAR_01831(hisD) VIBHAR_02554
            VSP: VS_2025(hisD)
            VEX: VEA_003848
            VFI: VF_1013(hisD)
            VFM: VFMJ11_1096(hisD)
            VSA: VSAL_I1134(hisD)
            PPR: PBPRA1091(hisD)
            PAE: PA4448(hisD)
            PAU: PA14_57780(hisD)
            PAP: PSPA7_5020(hisD)
            PAG: PLES_48271(hisD)
            PPU: PP_0966(hisD)
            PPF: Pput_1005(hisD)
            PPG: PputGB1_0973(hisD)
            PPW: PputW619_4249(hisD)
            PST: PSPTO_4438(hisD)
            PSB: Psyr_4133(hisD)
            PSP: PSPPH_4137(hisD)
            PFL: PFL_0929(hisD)
            PFO: Pfl01_0871(hisD)
            PFS: PFLU0896(hisD) PFLU1949
            PEN: PSEEN1107(hisD)
            PMY: Pmen_0884(hisD)
            PSA: PST_1046(hisD)
            CJA: CJA_2794(hisD)
            AVN: Avin_12930(hisD)
            PAR: Psyc_1902(hisD)
            PCR: Pcryo_2192(hisD)
            PRW: PsycPRwf_0503(hisD)
            ACI: ACIAD0663(hisD)
            ACD: AOLE_16315(hisD)
            ACB: A1S_0687
            ABM: ABSDF2839(hisD)
            ABY: ABAYE3131(hisD)
            ABC: ACICU_00632(hisD)
            ABB: ABBFA_002929(hisD)
            MCT: MCR_1746(hisD)
            SON: SO_2073(hisD)
            SDN: Sden_1617(hisD)
            SFR: Sfri_1719(hisD)
            SAZ: Sama_1942(hisD)
            SBL: Sbal_2426(hisD)
            SBM: Shew185_2419(hisD)
            SBN: Sbal195_2537(hisD)
            SBP: Sbal223_1932(hisD)
            SLO: Shew_2198(hisD)
            SPC: Sputcn32_2179(hisD)
            SSE: Ssed_2542(hisD)
            SPL: Spea_2457(hisD)
            SHE: Shewmr4_1799(hisD)
            SHM: Shewmr7_2178(hisD)
            SHN: Shewana3_1853(hisD)
            SHW: Sputw3181_1830(hisD)
            SHL: Shal_1823(hisD)
            SWD: Swoo_2091(hisD)
            SWP: swp_3003(hisD)
            SVO: SVI_2489(hisD)
            ILO: IL1835(hisD)
            CPS: CPS_2061(hisD) CPS_3890(hisD2)
            PHA: PSHAb0493(hisD)
            PAT: Patl_2881
            PSM: PSM_B0572(hisD)
            SDE: Sde_3168
            MAQ: Maqu_2701
            AMC: MADE_01117
            PIN: Ping_1656
            TTU: TERTU_3809(hisD)
            FBL: Fbal_1712
            LPN: lpg1199(hisD)
            LPF: lpl1207(hisD)
            LPP: lpp1201(hisD)
            LPC: LPC_0666(hisD)
            LPA: lpa_01857(hisD)
            LLO: LLO_1303(hisD)
            MCA: MCA1963(hisD)
            FPH: Fphi_0068
            TCX: Tcr_0989
            NOC: Noc_2778
            NHL: Nhal_0351
            NWA: Nwat_0310
            ALV: Alvin_2834
            AEH: Mlg_2215(hisD)
            HHA: Hhal_2112(hisD)
            TGR: Tgr7_0745(hisD)
            TKM: TK90_0378
            HNA: Hneap_0767
            HCH: HCH_05305
            CSA: Csal_2212
            HEL: HELO_1937(hisD)
            ABO: ABO_0562
            KKO: Kkor_0860
            MMW: Mmwyl1_2406
            AHA: AHA_2195(hisD)
            ASA: ASA_2102(hisD)
            TAU: Tola_1736
            AFE: Lferr_2650
            AFR: AFE_3041(hisD)
            BCI: BCI_0404(hisD)
            RMA: Rmag_0602(hisD)
            VOK: COSY_0556(hisD)
            GPB: HDN1F_06430(hisD)
            NMA: NMA1770(hisD)
            NME: NMB1581(hisD)
            NMC: NMC1501(hisD)
            NMN: NMCC_1485(hisD)
            NMI: NMO_1409(hisD)
            NGO: NGO1240(hisD)
            NGK: NGK_0267(hisD)
            NLA: NLA_7020(hisD)
            CVI: CV_0611(hisD)
            LHK: LHK_00184(hisD)
            RSO: RSc2952(hisD)
            RSC: RCFBP_10499(hisD)
            RSL: RPSI07_0547(hisD)
            RPI: Rpic_3229(hisD)
            RPF: Rpic12D_2882(hisD)
            REU: Reut_A3111(hisD) Reut_C6092
            REH: H16_A1694 H16_A3416(hisD)
            RME: Rmet_3248(hisD)
            CTI: RALTA_A2875(hisD)
            BMA: BMA2714(hisD)
            BMV: BMASAVP1_A3239(hisD)
            BML: BMA10229_A1788(hisD)
            BMN: BMA10247_2765(hisD)
            BPS: BPSL3139(hisD)
            BPM: BURPS1710b_3693(hisD)
            BPL: BURPS1106A_3724(hisD)
            BPD: BURPS668_3666(hisD)
            BPR: GBP346_A3851(hisD)
            BTE: BTH_I2993(hisD)
            BVI: Bcep1808_0404(hisD)
            BUR: Bcep18194_A3523(hisD)
            BCN: Bcen_1517 Bcen_2682(hisD)
            BCH: Bcen2424_0425(hisD) Bcen2424_6312
            BCM: Bcenmc03_0404(hisD) Bcenmc03_6970
            BCJ: BCAL0312(hisD)
            BAM: Bamb_0343(hisD)
            BAC: BamMC406_0352(hisD)
            BMU: Bmul_0328(hisD)
            BMJ: BMULJ_02926(hisD)
            BXE: Bxe_A0398(hisD) Bxe_C0309
            BPH: Bphy_2759(hisD) Bphy_7422
            BPY: Bphyt_3560(hisD)
            BGL: bglu_1g03310(hisD)
            BGE: BC1002_2818
            BRH: RBRH_02293
            PNU: Pnuc_0107
            PNE: Pnec_0106
            BPE: BP3768(hisD)
            BPA: BPP4267(hisD)
            BBR: BB4854(hisD)
            BPT: Bpet0138(hisD)
            BAV: BAV3314(hisD)
            AXY: AXYL_00190(hisD1) AXYL_01399(hisD2)
            RFR: Rfer_2946(hisD)
            POL: Bpro_0804(hisD)
            PNA: Pnap_0696(hisD)
            AAV: Aave_1024(hisD)
            AJS: Ajs_0760(hisD)
            DIA: Dtpsy_0727(hisD)
            VEI: Veis_0208(hisD) Veis_0769
            DAC: Daci_5524(hisD)
            VAP: Vapar_1165(hisD)
            VPE: Varpa_1251
            CTT: CtCNB1_0712
            ADN: Alide_0874 Alide_2313
            MPT: Mpe_A0831(hisD)
            HAR: HEAR3069(hisD)
            MMS: mma_3288(hisD)
            HSE: Hsero_4069(hisD)
            ZIN: ZICARI_184(hisD)
            LCH: Lcho_1587(hisD)
            TIN: Tint_0862
            NEU: NE0872(hisD)
            NET: Neut_1206(hisD)
            NMU: Nmul_A0819(hisD)
            EBA: ebA1299(hisD)
            AZO: azo0818(hisD)
            DAR: Daro_3387
            TMZ: Tmz1t_0900(hisD)
            TBD: Tbd_1713(hisD)
            MFA: Mfla_0248(hisD)
            MMB: Mmol_0311(hisD)
            MEH: M301_0302
            MEI: Msip34_0266(hisD)
            MEP: MPQ_0279(hisD)
            APP: CAP2UW1_4033
            SLT: Slit_0697
            GCA: Galf_0543
            HHE: HH1721(hisD)
            HMS: HMU12680(hisD)
            WSU: WS1587(hisD)
            TDN: Suden_0497(hisD)
            SKU: Sulku_0639
            CJE: Cj1598(hisD)
            CJR: CJE1770(hisD)
            CJJ: CJJ81176_1585(hisD)
            CJU: C8J_1500(hisD)
            CJN: ICDCCJ_1510
            CJD: JJD26997_1951(hisD)
            CFF: CFF8240_0519(hisD)
            CCV: CCV52592_0109(hisD)
            CHA: CHAB381_1216(hisD)
            CCO: CCC13826_2188(hisD)
            CLA: Cla_0098(hisD)
            ABU: Abu_0384(hisD)
            ANT: Arnit_0643
            SDL: Sdel_1337
            NIS: NIS_0566(hisD)
            SUN: SUN_1800(hisD)
            NSA: Nitsa_1362
            NAM: NAMH_0882(hisD)
            GSU: GSU3100(hisD)
            GME: Gmet_0384(hisD)
            GUR: Gura_4057(hisD)
            GLO: Glov_0822(hisD)
            GBM: Gbem_3704(hisD)
            GEO: Geob_0689(hisD)
            GEM: GM21_3799(hisD)
            PCA: Pcar_2688(hisD)
            PPD: Ppro_3042(hisD)
            DVU: DVU0796(hisD)
            DVL: Dvul_2178(hisD)
            DVM: DvMF_2814(hisD)
            DDE: Dde_1008(hisD)
            DDS: Ddes_1051(hisD)
            DMA: DMR_22040(hisD)
            DSA: Desal_2020(hisD)
            DAS: Daes_1231
            DBA: Dbac_0309(hisD)
            DRT: Dret_1370(hisD)
            DPS: DP1282(hisD)
            DAK: DaAHT2_1943
            DPR: Despr_0907
            DOL: Dole_3222
            DAL: Dalk_0826
            DAT: HRM2_03140(hisD1) HRM2_45560(hisD2)
            ADE: Adeh_0712(hisD)
            ACP: A2cp1_0749(hisD)
            AFW: Anae109_0753(hisD)
            ANK: AnaeK_0748(hisD)
            MXA: MXAN_4229(hisD)
            SCL: sce2464(hisD)
            HOH: Hoch_4273
            SAT: SYN_01792
            SFU: Sfum_3299(hisD)
            DBR: Deba_1224
            PUB: SAR11_0475(hisD) SAR11_0801(hisD)
            MLO: mll6456(hisD) mlr6649 mlr7107
            MCI: Mesci_2368 Mesci_2664
            MES: Meso_0190(hisD) Meso_1928
            PLA: Plav_0521
            SME: SMa0398(hisD2) SMc02307(hisD)
            SMD: Smed_0208(hisD) Smed_1713 Smed_4290 Smed_6310
            RHI: NGR_b04410 NGR_b16070(hisD1) NGR_c02240(hisD)
            ATU: Atu0537(hisD)
            ARA: Arad_12308 Arad_4040(hisD)
            AVI: Avi_0643(hisD)
            RET: RHE_CH00581(hisD)
            REC: RHECIAT_CH0000656(hisD) RHECIAT_PC0000802
            RLE: RL0613(hisD) pRL80041(hisD)
            RLT: Rleg2_0239(hisD) Rleg2_5007(hisD)
            RLG: Rleg_0267(hisD)
            BME: BMEI1668(hisD)
            BMI: BMEA_A0287(hisD)
            BMF: BAB1_0285(hisD)
            BMB: BruAb1_0280(hisD)
            BMC: BAbS19_I02600(hisD)
            BMS: BR0252(hisD)
            BMT: BSUIS_A0275(hisD)
            BOV: BOV_0270(hisD)
            BCS: BCAN_A0256(hisD)
            BMR: BMI_I256(hisD)
            OAN: Oant_0326(hisD) Oant_3581
            BJA: blr1256(hisD)
            BRA: BRADO6637(hisD)
            BBT: BBta_0897(hisD)
            RPA: RPA4531(hisD)
            RPB: RPB_4350(hisD)
            RPC: RPC_4417(hisD)
            RPD: RPD_4279(hisD)
            RPE: RPE_4484(hisD)
            RPT: Rpal_5022(hisD)
            RPX: Rpdx1_4734
            NWI: Nwi_0247(hisD)
            NHA: Nham_0286(hisD)
            OCA: OCAR_4730(hisD)
            XAU: Xaut_1231(hisD)
            AZC: AZC_3149(hisD)
            SNO: Snov_0129 Snov_0212 Snov_2959
            MEX: Mext_1984
            MEA: Mex_1p1961(hisD)
            MDI: METDI2749(hisD)
            MRD: Mrad2831_3512
            MET: M446_2638
            MPO: Mpop_1939
            MCH: Mchl_2261
            MNO: Mnod_4267 Mnod_4790
            BID: Bind_0668
            MSL: Msil_3070
            HDN: Hden_2713
            RVA: Rvan_0548
            HCI: HCDSEM_101(hisD)
            CCR: CC_2346(hisD)
            CCS: CCNA_02431(hisD)
            CAK: Caul_3588(hisD)
            CSE: Cseg_3130
            PZU: PHZ_c2199(hisD)
            BSB: Bresu_1043
            AEX: Astex_0817
            SIL: SPO0594(hisD) SPO0981(hisD) SPOA0202(hisD)
            SIT: TM1040_3563(hisD)
            RSP: RSP_0632(hisD) RSP_2155(hisD)
            RSH: Rsph17029_0829(hisD) Rsph17029_2284(hisD)
            RSQ: Rsph17025_0593(hisD)
            RSK: RSKD131_0466(hisD) RSKD131_1986(hisD)
            RCP: RCAP_rcc02558(hisD)
            JAN: Jann_1104 Jann_1398 Jann_2883(hisD)
            RDE: RD1_1068(hisD) RD1_3808(hisD) RD1_3948(hisD)
            PDE: Pden_1091 Pden_1959(hisD) Pden_3579
            DSH: Dshi_0979(hisD) Dshi_2034(hisD2) Dshi_2242(hisD3)
            KVU: EIO_2040(hisD)
            MMR: Mmar10_1614
            HNE: HNE_1346(hisD)
            HBA: Hbal_1769
            ZMO: ZMO1551
            ZMN: Za10_1655
            NAR: Saro_2920(hisD) Saro_3423
            SAL: Sala_2026(hisD)
            SWI: Swit_2776(hisD)
            SJP: SJA_C1-02790(hisD)
            ELI: ELI_02595(hisD)
            GOX: GOX0991(hisD)
            GBE: GbCGDNIH1_1031(hisD)
            ACR: Acry_2693
            GDI: GDI_1440(hisD)
            GDJ: Gdia_2140(hisD)
            APT: APA01_19890(hisD)
            RRU: Rru_A2771(hisD)
            RCE: RC1_1650(hisD)
            MAG: amb3342(hisD)
            AZL: AZL_d03600(hisD)
            PBR: PB2503_02002
            APB: SAR116_0046 SAR116_1319 SAR116_2138
            MGM: Mmc1_1220
            DIN: Selin_1974
            BSU: BSU34910(hisD)
            BSS: BSUW23_17110(hisD)
            BHA: BH3582(hisD)
            BAN: BA_1426(hisD)
            BAR: GBAA_1426(hisD)
            BAT: BAS1317(hisD)
            BAH: BAMEG_3169(hisD)
            BAI: BAA_1493(hisD)
            BAL: BACI_c14450(hisD)
            BCE: BC1406(hisD)
            BCA: BCE_1526(hisD)
            BCZ: BCZK1291(hisD)
            BCR: BCAH187_A1565(hisD)
            BCB: BCB4264_A1459(hisD)
            BCU: BCAH820_1497(hisD)
            BCG: BCG9842_B3885(hisD)
            BCQ: BCQ_1479(hisD)
            BCX: BCA_1461(hisD)
            BCY: Bcer98_1129(hisD)
            BTK: BT9727_1290(hisD)
            BTL: BALH_1261(hisD)
            BTB: BMB171_C1244(hisD)
            BWE: BcerKBAB4_1328(hisD)
            BLI: BL03408(hisD)
            BLD: BLi03736(hisD)
            BAY: RBAM_032120(hisD)
            BAO: BAMF_3337(hisD)
            BAE: BATR1942_15360(hisD)
            BCL: ABC1168 ABC3048(hisD)
            BPU: BPUM_3126(hisD)
            BPF: BpOF4_05380(hisD)
            BMQ: BMQ_5069(hisD)
            BMD: BMD_1657(hisD) BMD_5057(hisD)
            BSE: Bsel_1097
            BCO: Bcell_3538
            OIH: OB0551
            GKA: GK3075(hisD)
            GTN: GTNG_3025(hisD)
            GWC: GWCH70_2979(hisD)
            GYM: GYMC10_0146
            GYC: GYMC61_3156(hisD)
            GYA: GYMC52_3184
            GCT: GC56T3_3096
            GMC: GY4MC1_0397
            AFL: Aflv_2535(hisD)
            SAU: SA2470
            SAV: SAV2678
            SAW: SAHV_2662
            SAH: SaurJH1_2759
            SAJ: SaurJH9_2702
            SAM: MW2597
            SAS: SAS2563
            SAR: SAR2760(hisD)
            SAC: SACOL2702(hisD)
            SAX: USA300HOU_2679(hisD)
            SAA: SAUSA300_2611(hisD)
            SAO: SAOUHSC_03013
            SAE: NWMN_2576(hisD)
            SAD: SAAV_2752(hisD)
            SAB: SAB2554c(hisD)
            SEP: SE0272
            SER: SERP2305(hisD)
            SSP: SSP0429
            SCA: Sca_0635(hisD)
            SSD: SPSINT_2219
            LMO: lmo0567(hisD)
            LMF: LMOf2365_0596(hisD)
            LMH: LMHCC_2064(hisD)
            LMC: Lm4b_00593(hisD)
            LMN: LM5578_0595(hisD)
            LMY: LM5923_0594(hisD)
            LIN: lin0576(hisD)
            LWE: lwe0533(hisD)
            LSG: lse_0475(hisD)
            LSP: Bsph_0440(hisD)
            ESI: Exig_2366
            EAT: EAT1b_0083
            BBE: BBR47_52700(hisD)
            PJD: Pjdr2_0161
            PPY: PPE_00175
            PPM: PPSC2_c0167
            AAC: Aaci_0925
            BTS: Btus_2172 Btus_2894
            LLA: L0067(hisD)
            LLK: LLKF_1250(hisD)
            LLC: LACR_1332
            LLM: llmg_1295(hisD)
            SMU: SMU.1270(hisD)
            SMC: SmuNN2025_0785(hisD)
            STE: STER_1204(hisD)
            SSA: SSA_1446(hisD)
            SGO: SGO_1408(hisD)
            SGA: GALLO_1470(hisD)
            LPL: lp_2559(hisD)
            LPJ: JDM1_2059(hisD)
            LPS: LPST_C2109(hisD)
            LCA: LSEI_1433(hisD)
            LCB: LCABL_16550(hisD)
            LCZ: LCAZH_1421
            LFE: LAF_0757(hisD)
            LRH: LGG_01443(hisD)
            LRL: LC705_01460(hisD)
            LME: LEUM_1554
            LKI: LKI_08170
            LGS: LEGAS_0624(hisD)
            CAC: CA_C0937(hisD)
            CNO: NT01CX_1062(hisD)
            CTH: Cthe_2882
            CDF: CD1582(hisD)
            CDC: CD196_1504(hisD)
            CDL: CDR20291_1479(hisD)
            CBO: CBO1567(hisD)
            CBA: CLB_1587(hisD)
            CBH: CLC_1598(hisD)
            CBY: CLM_1808(hisD)
            CBB: CLD_2985(hisD)
            CBI: CLJ_B1674(hisD)
            CBT: CLH_2630(hisD)
            CBF: CLI_1649(hisD)
            CBE: Cbei_1317
            CKL: CKL_1295(hisD)
            CKR: CKR_1191(hisD)
            CPY: Cphy_2785
            CCE: Ccel_0382
            CLJ: CLJU_c11680(hisD)
            CSH: Closa_1979
            CCB: Clocel_3924
            CST: CLOST_0521(hisD)
            AMT: Amet_0572
            STH: STH2837(hisD)
            SWO: Swol_1768
            SLP: Slip_0612
            VPR: Vpar_0126
            AFN: Acfer_0917
            DSY: DSY3913(hisD)
            DHD: Dhaf_1492(hisD)
            DRM: Dred_2355(hisD)
            DAE: Dtox_0752
            PTH: PTH_1680(hisD) PTH_2538(hisD)
            DAU: Daud_1627
            TJR: TherJR_0836
            HMO: HM1_3051(hisD)
            EEL: EUBELI_01022
            ERE: EUBREC_1687
            ELM: ELI_0361
            BPB: bpr_I1449(hisD)
            EHA: Ethha_1440
            RAL: Rumal_2118
            TMR: Tmar_0595
            TTE: TTE2138(hisD)
            TEX: Teth514_1001(hisD)
            TPD: Teth39_0516(hisD)
            TIT: Thit_1819
            TMT: Tmath_1798
            TBO: Thebr_0531
            CHY: CHY_1085(hisD)
            MTA: Moth_2035
            ADG: Adeg_0313
            CSC: Csac_2025
            ATE: Athe_1478
            COB: COB47_1076
            CHD: Calhy_1258
            COW: Calow_1257
            CKI: Calkr_1463
            CKN: Calkro_1232
            TTM: Tthe_0560
            NTH: Nther_1898
            HOR: Hore_02200
            HAS: Halsa_2269
            AAR: Acear_1459
            MTU: Rv1599(hisD)
            MTC: MT1635(hisD)
            MRA: MRA_1609(hisD)
            MTF: TBFG_11615(hisD)
            MTB: TBMG_02395(hisD)
            MBO: Mb1625(hisD)
            MBB: BCG_1637(hisD)
            MBT: JTY_1612(hisD)
            MLE: ML1257(hisD)
            MLB: MLBr_01257(hisD)
            MPA: MAP1293(hisD)
            MAV: MAV_3187(hisD)
            MSM: MSMEG_2012(hisD) MSMEG_3205(hisD) MSMEG_5656(hisD)
            MUL: MUL_1572(hisD)
            MVA: Mvan_2804(hisD)
            MGI: Mflv_3613(hisD)
            MAB: MAB_2670c(hisD)
            MMC: Mmcs_3063(hisD)
            MKM: Mkms_3122(hisD)
            MJL: Mjls_3079(hisD)
            MSP: Mspyr1_29560
            MMI: MMAR_2395(hisD)
            CGL: NCgl2021(hisD)
            CGB: cg2305(hisD)
            CGT: cgR_0116 cgR_1986(hisD)
            CEF: CE2003(hisD)
            CDI: DIP1566(hisD)
            CJK: jk0786(hisD)
            CUR: cur_1176(hisD)
            CAR: cauri_1625(hisD)
            CKP: ckrop_0787(hisD)
            CPU: cpfrc_01365(hisD)
            NFA: nfa18450(hisD)
            RHA: RHA1_ro01031(hisD) RHA1_ro04557(hisD2)
            RER: RER_34520(hisD)
            ROP: ROP_07570(hisD) ROP_44710(hisD)
            REQ: REQ_26790(hisD)
            GBR: Gbro_2960
            TPR: Tpau_2023
            SRT: Srot_1833
            SCO: SCO2054(hisD)
            SMA: SAV_6153(hisD)
            SGR: SGR_5450(hisD)
            SCB: SCAB_68351(hisD) SCAB_89041(hisD)
            LXX: Lxx15120(hisD)
            CMI: CMM_1848(hisD)
            CMS: CMS_1384(hisD)
            ART: Arth_1585(hisD) Arth_4260(hisD)
            AAU: AAur_1724(hisD)
            ACH: Achl_1585(hisD)
            AAI: AARI_20630(hisD)
            RSA: RSal33209_2479(hisD)
            KRH: KRH_14700(hisD)
            MLU: Mlut_19310(hisD)
            BFA: Bfae_22020(hisD)
            JDE: Jden_1089
            KSE: Ksed_09670(hisD)
            XCE: Xcel_1302
            SKE: Sked_22650
            CFL: Cfla_1611
            ICA: Intca_1538
            PAC: PPA1152(hisD)
            PAK: HMPREF0675_4213(hisD)
            PFR: PFREUD_11790(hisD)
            NCA: Noca_3045(hisD)
            KFL: Kfla_2919
            TFU: Tfu_1150(hisD)
            NDA: Ndas_3192
            TCU: Tcur_2897
            SRO: Sros_2907
            FRA: Francci3_3027(hisD)
            FRE: Franean1_1916(hisD)
            FRI: FraEuI1c_4994
            FAL: FRAAL5004(hisD)
            ACE: Acel_1058(hisD)
            NML: Namu_3163(hisD)
            GOB: Gobs_3242
            KRA: Krad_2498 Krad_3181(hisD)
            SEN: SACE_3119(hisD2) SACE_5778(hisD)
            SVI: Svir_10870(hisD)
            TBI: Tbis_1434
            AMD: AMED_2251(hisD)
            AMI: Amir_5722(hisD)
            STP: Strop_3196(hisD)
            SAQ: Sare_3422(hisD)
            MAU: Micau_4455
            MIL: ML5_3848
            CAI: Caci_5730(hisD)
            SNA: Snas_3997
            MCU: HMPREF0573_11853(hisD)
            BLO: BL1295(hisD)
            BLJ: BLD_0152(hisD)
            BLN: Blon_0823(hisD)
            BLL: BLJ_1330(hisD)
            BLB: BBMN68_180(hisD)
            BAD: BAD_1129(hisD)
            BLA: BLA_0803(hisD)
            BLC: Balac_1225(hisD)
            BLT: Balat_1225(hisD)
            BDE: BDP_1583
            BBI: BBIF_0549(hisD)
            BBP: BBPR_0524(hisD)
            RXY: Rxyl_1102
            CWO: Cwoe_0128 Cwoe_3531
            AFO: Afer_1111
            SHI: Shel_15280
            ELE: Elen_1079
            OLS: Olsu_1300
            SSM: Spirs_2270
            LIL: LA_2515(hisD)
            LIC: LIC11453(hisD)
            LBJ: LBJ_1668(hisD)
            LBL: LBL_1887(hisD)
            LBI: LEPBI_I1825(hisD)
            LBF: LBF_1772(hisD)
            BHY: BHWA1_02328(hisD)
            BRM: Bmur_1963
            ABA: Acid345_3683
            ACA: ACP_2340(hisD)
            TSA: AciPR4_3063
            SUS: Acid_3855
            BTH: BT_0201(hisD)
            BFR: BF3189(hisD)
            BFS: BF3029(hisD)
            BVU: BVU_2362(hisD)
            BHL: Bache_2987
            PDI: BDI_0967(hisD)
            PPN: Palpr_3042
            APS: CFPG_031(hisD)
            PRU: PRU_0389(hisD)
            SRU: SRU_2127(hisD)
            SRM: SRM_02351(hisD)
            RMR: Rmar_0666
            CHU: CHU_1861(hisD)
            DFE: Dfer_1141
            SLI: Slin_1784
            LBY: Lbys_3586
            MTT: Ftrac_0078
            CPI: Cpin_1818
            PHE: Phep_3192
            GFO: GFO_1763(hisD)
            FJO: Fjoh_2877(hisD)
            FPS: FP0959(hisD)
            RBI: RB2501_15154
            ZPR: ZPR_2387
            CAT: CA2559_09011
            FBC: FB2170_10921
            CAO: Celal_4157
            FBA: FIC_00842
            BBL: BLBBGE_434(hisD)
            BPI: BPLAN_206(hisD)
            FSU: Fisuc_2758
            LBA: Lebu_1238
            STR: Sterm_2175
            IPO: Ilyop_2701
            OTE: Oter_0190
            CAA: Caka_2357
            MIN: Minf_0243(hisD)
            AMU: Amuc_1714
            GAU: GAU_0139(hisD)
            RBA: RB1584(hisD)
            PSL: Psta_4385
            PLM: Plim_2170
            IPA: Isop_3602
            EMI: Emin_0715
            RSD: TGRD_499
            TAI: Taci_0033
            ACO: Amico_0684
            SYN: slr0682(hisD) slr1848(hisD)
            SYW: SYNW0610(hisD)
            SYC: syc2504_c(hisD)
            SYF: Synpcc7942_1519(hisD)
            SYD: Syncc9605_2070(hisD)
            SYE: Syncc9902_0602(hisD)
            SYG: sync_2362(hisD)
            SYR: SynRCC307_1962(hisD)
            SYX: SynWH7803_2065(hisD)
            SYP: SYNPCC7002_A2049(hisD)
            CYA: CYA_0591(hisD)
            CYB: CYB_0073(hisD)
            TEL: tll2252(hisD)
            MAR: MAE_16690(hisD) MAE_21460(hisD)
            CYT: cce_2314(hisD) cce_4520(hisD2)
            CYP: PCC8801_0205(hisD) PCC8801_2651
            CYC: PCC7424_0738 PCC7424_2689(hisD)
            CYN: Cyan7425_5103(hisD)
            CYH: Cyan8802_0200(hisD) Cyan8802_3453
            CYJ: Cyan7822_2269 Cyan7822_5327
            GVI: gvip194(hisD)
            ANA: all1591(hisD) alr3056(hisD)
            NPU: Npun_R4982(hisD)
            AVA: Ava_0855 Ava_4204(hisD)
            NAZ: Aazo_1020
            PMA: Pro1643(hisD)
            PMM: PMM1488(hisD)
            PMT: PMT1510(hisD)
            PMN: PMN2A_1019(hisD)
            PMI: PMT9312_1581(hisD)
            PMB: A9601_16921(hisD)
            PMC: P9515_16681(hisD)
            PMF: P9303_04331(hisD)
            PMG: P9301_16791(hisD)
            PMH: P9215_17571(hisD)
            PMJ: P9211_16101(hisD)
            PME: NATL1_18891(hisD)
            TER: Tery_2942(hisD)
            AMR: AM1_2902(hisD) AM1_3589(hisD)
            CTE: CT0546(hisD)
            CPC: Cpar_1440(hisD)
            CCH: Cag_1289(hisD)
            CPH: Cpha266_0801(hisD)
            CPB: Cphamn1_1819(hisD)
            CLI: Clim_0513(hisD)
            PVI: Cvib_0596(hisD)
            PLT: Plut_0554(hisD)
            PPH: Ppha_0849(hisD)
            PAA: Paes_0693(hisD)
            CTS: Ctha_0232(hisD)
            DET: DET0844(hisD)
            DEH: cbdb_A826(hisD)
            DEB: DehaBAV1_0763(hisD)
            DEV: DhcVS_748(hisD)
            DEG: DehalGT_0724
            DLY: Dehly_0654
            RRS: RoseRS_3179
            RCA: Rcas_2906
            CAU: Caur_2694
            CAG: Cagg_0934
            CHL: Chy400_2911
            HAU: Haur_2013
            TRO: trd_0637(hisD)
            STI: Sthe_1676
            ATM: ANT_23750(hisD)
            DRA: DR_2140
            DGE: Dgeo_0584
            DDR: Deide_03740(hisD)
            DMR: Deima_1474
            TRA: Trad_1355
            TTH: TTC0370(hisD)
            TTJ: TTHA0722(hisD)
            TSC: TSC_c08580(hisD)
            MRB: Mrub_0766 Mrub_2545
            MSV: Mesil_2365
            OPR: Ocepr_0752
            AAE: aq_782(hisD)
            HYA: HY04AAS1_0891
            HTH: HTH_0355(hisD)
            TAL: Thal_1450
            SUL: SYO3AOP1_1125
            SAF: SULAZ_1021(hisD)
            PMX: PERMA_1846(hisD)
            TAM: Theam_1327
            TMA: TM1041(hisD)
            TPT: Tpet_1709(hisD)
            TRQ: TRQ2_1767(hisD)
            TNA: CTN_1525(hisD)
            TNP: Tnap_1723
            PMO: Pmob_1017(hisD)
            DTH: DICTH_0993(hisD)
            DTU: Dtur_1121
            TYE: THEYE_A1817(hisD)
            NDE: NIDE0981(hisD)
            TTR: Tter_0659
            DDF: DEFDS_1965(hisD)
            DAP: Dacet_0409
            CNI: Calni_1277
            MJA: MJ_1456(hisD)
            MFE: Mefer_1145(hisD)
            MVU: Metvu_1444(hisD)
            MFS: MFS40622_0893
            MIF: Metin_0099
            MMP: MMP0968(hisD)
            MMQ: MmarC5_0791(hisD)
            MMX: MmarC6_1687(hisD)
            MMZ: MmarC7_0213(hisD)
            MAE: Maeo_0863(hisD)
            MVN: Mevan_0291(hisD)
            MVO: Mvol_0159
            MAC: MA3201(hisD)
            MBA: Mbar_A3507(hisD)
            MMA: MM_0424(hisD)
            MBU: Mbur_1103(hisD)
            MMH: Mmah_0561
            MEV: Metev_0178
            MTP: Mthe_0843(hisD)
            MHU: Mhun_2531(hisD)
            MLA: Mlab_0461(hisD)
            MEM: Memar_1876(hisD)
            MPI: Mpet_2395
            MBN: Mboo_2149(hisD)
            MPL: Mpal_2206(hisD)
            MPD: MCP_0704(hisD)
            MTH: MTH225(hisD)
            MMG: MTBMA_c06740(hisD)
            MST: Msp_0134(hisD)
            MSI: Msm_1238(hisD)
            MRU: mru_1015(hisD)
            MFV: Mfer_0590
            MKA: MK0711(hisD)
            AFU: AF0212(hisD)
            APO: Arcpr_0997
            FPL: Ferp_1527
            HAL: VNG1444G(hisD)
            HSL: OE3071F(hisD)
            HMA: rrnAC0272(hisD)
            HWA: HQ2720A(hisD)
            NPH: NP2876A(hisD)
            HLA: Hlac_2478(hisD)
            HUT: Huta_0450(hisD)
            HMU: Hmuk_2450(hisD)
            HTU: Htur_1869
            NMG: Nmag_0023
            HVO: HVO_2675(hisD)
            HJE: HacjB3_07080(hisD)
            HBO: Hbor_11320
            PTO: PTO1336(hisD)
            PFU: PF1659(hisD)
            TKO: TK0244(hisD)
            TON: TON_0880(hisD)
            TGA: TGAM_1608(hisD)
            TBA: TERMP_00438
            RCI: RCIX41(hisD)
            IHO: Igni_0384
            IAG: Igag_1574
            SSO: SSO0599(hisD)
            STO: ST1464(hisD)
            SAI: Saci_1579(hisD)
            SIS: LS215_1643(hisD)
            SIA: M1425_1535(hisD)
            SIM: M1627_1650(hisD)
            SID: M164_1532(hisD)
            SIY: YG5714_1539(hisD)
            SIN: YN1551_1297(hisD)
            SII: LD85_1742
            MSE: Msed_1947(hisD)
            PAI: PAE0988
            PIS: Pisl_1215
            PCL: Pcal_0136
            PAS: Pars_0167
            CMA: Cmaq_1407
            TNE: Tneu_0153
            VDI: Vdis_0596
            NMR: Nmar_1558
            CSY: CENSYa_2036
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.23
            IUBMB Enzyme Nomenclature: 1.1.1.23
            ExPASy - ENZYME nomenclature database: 1.1.1.23
            BRENDA, the Enzyme Database: 1.1.1.23
            CAS: 9028-27-7
///
ENTRY       EC 1.1.1.24                 Enzyme
NAME        quinate dehydrogenase;
            quinic dehydrogenase;
            quinate:NAD oxidoreductase;
            quinate 5-dehydrogenase;
            quinate:NAD+ 5-oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-quinate:NAD+ 3-oxidoreductase
REACTION    L-quinate + NAD+ = 3-dehydroquinate + NADH + H+ [RN:R01872]
ALL_REAC    R01872
SUBSTRATE   L-quinate [CPD:C00296];
            NAD+ [CPD:C00003]
PRODUCT     3-dehydroquinate [CPD:C00944];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     The enzyme is specific for quinate as substrate; phenylpyruvate,
            phenylalanine, cinnamate and shikimate will not act as substrates.
            NAD+ cannot be replaced by NADP+.
REFERENCE   1
  AUTHORS   Gamborg, O.L.
  TITLE     Aromatic metabolism in plants. III. Quinate dehydrogenase from mung
            bean cell suspension cultures.
  JOURNAL   Biochim. Biophys. Acta 128 (1966) 483-491.
REFERENCE   2  [PMID:13208693]
  AUTHORS   MITSUHASHI S, DAVIS BD.
  TITLE     Aromatic biosynthesis. XIII. Conversion of quinic acid to
            5-dehydroquinic acid by quinic dehydrogenase.
  JOURNAL   Biochim. Biophys. Acta. 15 (1954) 268-80.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
PATHWAY     ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ORTHOLOGY   K09484  quinate dehydrogenase
GENES       NCR: NCU06025
            PAN: PODANSg2393
            MGR: MGG_07781(MG07781.4)
            FGR: FG05704.1
            SSL: SS1G_09188
            BFU: BC1G_01047
            ANI: AN1137.2
            AFM: AFUA_1G11590
            NFI: NFIA_013950
            AOR: AO090038000263
            ANG: An03g03710
            AFV: AFLA_068130
            ACT: ACLA_024050
            PCS: Pc13g08380
            PNO: SNOG_11439
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.24
            IUBMB Enzyme Nomenclature: 1.1.1.24
            ExPASy - ENZYME nomenclature database: 1.1.1.24
            BRENDA, the Enzyme Database: 1.1.1.24
            CAS: 9028-28-8
///
ENTRY       EC 1.1.1.25                 Enzyme
NAME        shikimate dehydrogenase;
            dehydroshikimic reductase;
            shikimate oxidoreductase;
            shikimate:NADP+ oxidoreductase;
            5-dehydroshikimate reductase;
            shikimate 5-dehydrogenase;
            5-dehydroshikimic reductase;
            DHS reductase;
            shikimate:NADP+ 5-oxidoreductase;
            AroE
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     shikimate:NADP+ 3-oxidoreductase
REACTION    shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+ [RN:R02413]
ALL_REAC    R02413
SUBSTRATE   shikimate [CPD:C00493];
            NADP+ [CPD:C00006]
PRODUCT     3-dehydroshikimate [CPD:C02637];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     NAD+ cannot replace NADP+ [3]. In higher organisms, this enzyme
            forms part of a multienzyme complex with EC 4.2.1.10,
            3-dehydroquinate dehydratase [4].
REFERENCE   1  [PMID:13686342]
  AUTHORS   BALINSKY D, DAVIES DD.
  TITLE     Aromatic biosynthesis in higher plants. 1. Preparation and
            properties of dehydroshikimic reductase.
  JOURNAL   Biochem. J. 80 (1961) 292-6.
  ORGANISM  Saccharomyces cerevisiae [GN:sce], Escherichia coli [GN:eco],
            Spinacia oleracea, Pisum sativum, Klebsiella pneumoniae [GN:kpn],
            Euglena gracilis
REFERENCE   2  [PMID:13208693]
  AUTHORS   MITSUHASHI S, DAVIS BD.
  TITLE     Aromatic biosynthesis. XIII. Conversion of quinic acid to
            5-dehydroquinic acid by quinic dehydrogenase.
  JOURNAL   Biochim. Biophys. Acta. 15 (1954) 268-80.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
REFERENCE   3  [PMID:14367339]
  AUTHORS   YANIV H, GILVARG C.
  TITLE     Aromatic biosynthesis. XIV. 5-Dehydroshikimic reductase.
  JOURNAL   J. Biol. Chem. 213 (1955) 787-95.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   4  [PMID:3883995]
  AUTHORS   Chaudhuri S, Coggins JR.
  TITLE     The purification of shikimate dehydrogenase from Escherichia coli.
  JOURNAL   Biochem. J. 226 (1985) 217-23.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   5  [PMID:3277621]
  AUTHORS   Anton IA, Coggins JR.
  TITLE     Sequencing and overexpression of the Escherichia coli aroE gene
            encoding shikimate dehydrogenase.
  JOURNAL   Biochem. J. 249 (1988) 319-26.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   6  [PMID:12837789]
  AUTHORS   Ye S, Von Delft F, Brooun A, Knuth MW, Swanson RV, McRee DE.
  TITLE     The crystal structure of shikimate dehydrogenase (AroE) reveals a
            unique NADPH binding mode.
  JOURNAL   J. Bacteriol. 185 (2003) 4144-51.
  ORGANISM  Haemophilus influenzae
PATHWAY     ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00014  shikimate dehydrogenase
            K13830  pentafunctional AROM polypeptide
            K13832  3-dehydroquinate dehydratase / shikimate dehydrogenase
GENES       ATH: AT3G06350(MEE32)
            POP: POPTR_240966(DHQD3) POPTR_565769(DHQD4) POPTR_570919(DHQD2)
                 POPTR_742170(DHQD1) POPTR_824203(DHQD5)
            RCU: RCOM_0556770 RCOM_0679510 RCOM_1429640 RCOM_1429650
            VVI: 100242676 100243536 100248678 100253776
            OSA: 4325444
            SBI: SORBI_03g018040 SORBI_08g016970
            ZMA: 100191894(sad1) 100272333 100285997(cl40355_1)
            PPP: PHYPADRAFT_62585
            CRE: CHLREDRAFT_196935(SHKD1)
            VCN: VOLCADRAFT_82062
            OLU: OSTLU_39392
            OTA: Ot12g02660
            CME: CMK269C
            SCE: YDR127W(ARO1)
            AGO: AGOS_AGR066W
            KLA: KLLA0F19712g
            LTH: KLTH0G13090g
            PPA: PAS_chr3_0506
            VPO: Kpol_1033p17
            ZRO: ZYRO0D06578g
            CGR: CAGL0M11484g
            PIC: PICST_89141
            PGU: PGUG_03670
            LEL: LELG_05773
            CAL: CaO19.12175(ARO1) CaO19.4704(ARO1)
            CTP: CTRG_00061
            CDU: CD36_40930
            YLI: YALI0F12639g
            CLU: CLUG_04813
            NCR: NCU01632
            PAN: PODANSg7061
            MGR: MGG_01128(MG01128.4)
            FGR: FG04287.1
            SSL: SS1G_13550
            AFM: AFUA_1G13740 AFUA_3G14790 AFUA_3G14800
            NFI: NFIA_011760 NFIA_062460 NFIA_062470
            AOR: AO090012000502
            AFV: AFLA_017680
            ACT: ACLA_021700
            PCS: Pc16g12160
            CIM: CIMG_03391
            CPW: CPC735_008210
            URE: UREG_07217
            PNO: SNOG_01444 SNOG_10413
            TML: GSTUM_00004770001
            SPO: SPAC1834.02(aro1)
            CNE: CNB01990
            CNB: CNBB3730
            LBC: LACBIDRAFT_233717
            MPR: MPER_05383
            CCI: CC1G_09809
            SCM: SCHCODRAFT_83545
            UMA: UM03607.1
            MGL: MGL_3989
            MBR: MONBRDRAFT_32780
            PTI: PHATRDRAFT_45535
            TPS: THAPSDRAFT_268552
            PIF: PITG_17925
            ECO: b3281(aroE)
            ECJ: JW3242(aroE)
            ECD: ECDH10B_3456(aroE)
            EBW: BWG_2972(aroE)
            ECE: Z4652(aroE)
            ECS: ECs4147(aroE)
            ECF: ECH74115_4604(aroE)
            ETW: ECSP_4252(aroE)
            EOJ: ECO26_4383(aroE)
            EOI: ECO111_4101(aroE)
            EOH: ECO103_4013(aroE)
            ECG: E2348C_3544(aroE)
            EOK: G2583_4000(aroE)
            ECC: c4042(aroE)
            ECP: ECP_3369(aroE)
            ECI: UTI89_C3726(aroE)
            ECV: APECO1_3165(aroE)
            ECX: EcHS_A3475(aroE)
            ECW: EcE24377A_3764(aroE)
            ECM: EcSMS35_3577(aroE) EcSMS35_4475
            ECY: ECSE_3556(aroE)
            ECR: ECIAI1_3431(aroE)
            ECQ: ECED1_3945(aroE)
            ECK: EC55989_3698(aroE)
            ECT: ECIAI39_3775(aroE) ECIAI39_4411
            EUM: ECUMN_3755(aroE)
            ECZ: ECS88_3669(aroE)
            ECL: EcolC_0432(aroE)
            EBR: ECB_03132(aroE)
            EBD: ECBD_0470(aroE)
            EFE: EFER_0091(aroE) EFER_2592 EFER_3265(aroE)
            STY: STY3924(aroE) STY4396(aroE)
            STT: t3664(aroE) t4103(aroE)
            STM: STM3401(aroE) STM3859(aroE)
            SPT: SPA3268(aroE)
            SEK: SSPA3047(aroE)
            SPQ: SPAB_04242(aroE) SPAB_04800
            SEI: SPC_3470(aroE) SPC_3944(aroE)
            SEC: SC3337(aroE) SC3772(aroE)
            SEH: SeHA_C3705(aroE) SeHA_C4190
            SEE: SNSL254_A3670(aroE) SNSL254_A4140
            SEW: SeSA_A3598(aroE) SeSA_A4068
            SEA: SeAg_B3597(aroE) SeAg_B4084
            SED: SeD_A3768(aroE) SeD_A4248
            SEG: SG3574 SG4038(aroE)
            SET: SEN3229(aroE) SEN3673
            SES: SARI_04226(aroE)
            YPE: YPO0246(aroE) YPO1610(aroE)
            YPK: y1769(aroE) y4028(aroE)
            YPA: YPA_1912 YPA_3226(aroE)
            YPN: YPN_2019 YPN_3822(aroE)
            YPM: YP_0245(aroE) YP_2244(aroE)
            YPP: YPDSF_0169(aroE) YPDSF_1837
            YPG: YpAngola_A0622(aroE)
            YPZ: YPZ3_0211(aroE) YPZ3_2079
            YPS: YPTB2454(aroE) YPTB3660(aroE)
            YPI: YpsIP31758_1587 YpsIP31758_3877(aroE)
            YPY: YPK_0321(aroE) YPK_1695
            YPB: YPTS_2538 YPTS_3852(aroE)
            YEN: YE1700 YE3884(aroE)
            SFL: SF3313(aroE)
            SFX: S3537(aroE)
            SFV: SFV_3302(aroE)
            SSN: SSON_3422(aroE)
            SBO: SBO_3275(aroE)
            SBC: SbBS512_E3666(aroE)
            SDY: SDY_3458(aroE)
            ECA: ECA3995(aroE)
            PCT: PC1_3784
            PWA: Pecwa_3963(aroE)
            ETA: ETA_25900 ETA_31230(aroE)
            EPY: EpC_33360(aroE)
            EAM: EAMY_3345(aroE)
            EAY: EAM_3157(aroE)
            EBI: EbC_05000 EbC_40920(aroE)
            PLU: plu4691(aroE)
            PAY: PAU_04173(aroE)
            BUC: BU493(aroE)
            BAS: BUsg474(aroE)
            BAB: bbp437(aroE)
            BCC: BCc_312(aroE)
            BAP: BUAP5A_486(aroE)
            BAU: BUAPTUC7_487(aroE)
            SGL: SG2242(aroE)
            ENT: Ent638_3713(aroE)
            ENC: ECL_04658
            ESC: Entcl_0433
            ESA: ESA_00044(aroE)
            CTU: Ctu_38090(aroE)
            KPN: KPN_00075(aroE) KPN_00387 KPN_02128 KPN_03682(aroE) KPN_04401
            KPE: KPK_0434(aroE) KPK_2195 KPK_4297 KPK_4667(aroE) KPK_5273
            KPU: KP1_0890(aroE) KP1_1255 KP1_3223 KP1_5000(aroE)
            KVA: Kvar_0422 Kvar_2147 Kvar_3994 Kvar_4308 Kvar_4845
            CKO: CKO_04694(aroE)
            CRO: ROD_04821 ROD_45401(aroE)
            SPE: Spro_4506(aroE)
            PMR: PMI3292(aroE)
            EIC: NT01EI_3347 NT01EI_3555(aroE)
            ETR: ETAE_2934(aroE1) ETAE_3194(aroE2)
            BFL: Bfl221(aroE)
            BPN: BPEN_228(aroE)
            BVA: BVAF_222(aroE)
            HDE: HDEF_1254(aroE)
            DDA: Dd703_0444
            DDC: Dd586_3698
            DDD: Dda3937_00722 Dda3937_01528(aroE)
            DZE: Dd1591_0361
            XBO: XBJ1_4206(aroE)
            XNE: XNC1_0354(aroE)
            PAM: PANA_0701(aroE) PANA_3584(aroE)
            PVA: Pvag_2850(aroE)
            PAO: Pat9b_2993 Pat9b_3603 Pat9b_4384
            RIP: RIEPE_0420(aroE)
            HIN: HI0607(aroE) HI0655(aroE)
            HIT: NTHI0776(aroE) NTHI0862(aroE)
            HIP: CGSHiEE_02010 CGSHiEE_08920(aroE)
            HIQ: CGSHiGG_06560(aroE) CGSHiGG_06975
            HIF: HIBPF16030 HIBPF16240
            HIL: HICON_06910 HICON_07400
            HDU: HD0415(aroE)
            HAP: HAPS_1181(aroE) HAPS_1936(aroE)
            HSO: HS_0006(aroE)
            HSM: HSM_1897(aroE)
            PMU: PM1271(aroE) PM1429(aroE)
            MSU: MS0133(aroE) MS2315(aroE)
            APL: APL_1139(aroE)
            APJ: APJL_1158(aroE)
            APA: APP7_1197(aroE)
            ASU: Asuc_0337(aroE)
            AAP: NT05HA_1165 NT05HA_2300(aroE)
            AAT: D11S_0227(aroE) D11S_1096
            XFA: XF0624(aroE)
            XFT: PD1532(aroE)
            XFM: Xfasm12_1685(aroE)
            XFN: XfasM23_1617(aroE)
            XCC: XCC3953(aroE)
            XCB: XC_4041(aroE)
            XCA: xccb100_4141(aroE)
            XCV: XCV4126(aroE)
            XAC: XAC4034(aroE)
            XOO: XOO4712(aroE)
            XOM: XOO_0372(aroE)
            XOP: PXO_02821(aroE)
            XAL: XALc_2993(aroE)
            SML: Smlt4495(aroE)
            SMT: Smal_3856(aroE)
            PSU: Psesu_2832
            VCH: VC0056(aroE)
            VCO: VC0395_A2464(aroE)
            VCM: VCM66_0056(aroE)
            VCJ: VCD_001524(aroE)
            VVU: VV1_1057(aroE)
            VVY: VV3215(aroE)
            VVM: VVM_00095
            VPA: VP3033(aroE)
            VHA: VIBHAR_00382(aroE)
            VSP: VS_3117(aroE)
            VEX: VEA_002067
            VFI: VF_2535(aroE)
            VFM: VFMJ11_2666(aroE)
            VSA: VSAL_I0083(aroE)
            PPR: PBPRA3571(aroE)
            PAE: PA0025(aroE) PA0244
            PAU: PA14_00290(aroE) PA14_03020(aroE)
            PAP: PSPA7_0026(aroE) PSPA7_0329
            PAG: PLES_00241(aroE) PLES_02411
            PPU: PP_0074(aroE) PP_2406(aroE) PP_2608 PP_3002(aroE-2)
                 PP_3768(aroE)
            PPF: Pput_0090(aroE) Pput_1995 Pput_2691 Pput_3117 Pput_3289
            PPG: PputGB1_0090(aroE) PputGB1_2040 PputGB1_2135 PputGB1_3217
            PPW: PputW619_0093(aroE) PputW619_1912 PputW619_2099 PputW619_2153
            PST: PSPTO_0169(aroE) PSPTO_2348 PSPTO_2685
            PSB: Psyr_0025(aroE) Psyr_2132(aroE) Psyr_2418(aroE)
            PSP: PSPPH_0027(aroE) PSPPH_2107 PSPPH_2576
            PFL: PFL_0028(aroE) PFL_4005(aroE) PFL_5382(aroE)
            PFO: Pfl01_0023(aroE) Pfl01_3713(aroE) Pfl01_4903(aroE)
            PFS: PFLU0024(aroE) PFLU2134 PFLU5365(aroE)
            PEN: PSEEN0031(aroE) PSEEN2020 PSEEN3214
            PMY: Pmen_0061(aroE)
            PSA: PST_0027(aroE)
            CJA: CJA_3588(aroE)
            AVN: Avin_00230(aroE) Avin_03620 Avin_20210 Avin_38080 Avin_46700
            PAR: Psyc_0139(aroE)
            PCR: Pcryo_0150
            PRW: PsycPRwf_0119
            ACI: ACIAD0418(aroE)
            ACD: AOLE_01940(aroE) AOLE_08765
            ACB: A1S_3109(aroE)
            ABM: ABSDF0386(aroE)
            ABY: ABAYE0377(aroE)
            ABC: ACICU_03310(aroE)
            ABN: AB57_3561(aroE)
            ABB: ABBFA_000402(aroE)
            MCT: MCR_0233(aroE)
            SON: SO_0040(aroE)
            SDN: Sden_0034(aroE)
            SFR: Sfri_0034(aroE)
            SAZ: Sama_0052
            SBL: Sbal_0040(aroE)
            SBM: Shew185_0035(aroE)
            SBN: Sbal195_0039(aroE)
            SBP: Sbal223_0039(aroE)
            SLO: Shew_3727(aroE)
            SPC: Sputcn32_0032(aroE)
            SSE: Ssed_0043
            SPL: Spea_0040
            SHE: Shewmr4_0037(aroE)
            SHM: Shewmr7_0035(aroE)
            SHN: Shewana3_0043(aroE)
            SHW: Sputw3181_0032(aroE)
            SHL: Shal_0035
            SWD: Swoo_0047
            SWP: swp_0066
            SVO: SVI_0073(aroE)
            ILO: IL0024(aroE)
            CPS: CPS_0030(aroE)
            PHA: PSHAa0031(aroE)
            PAT: Patl_0031
            PSM: PSM_A0037
            SDE: Sde_0026
            MAQ: Maqu_0048(aroE)
            AMC: MADE_00031
            PIN: Ping_0071(aroE) Ping_3002
            TTU: TERTU_0043(aroE)
            FBL: Fbal_0033
            CBU: CBU_0010(aroE)
            CBS: COXBURSA331_A2191(aroE)
            CBD: CBUD_0135(aroE)
            CBG: CbuG_0279(aroE)
            CBC: CbuK_0199(aroE)
            LPN: lpg2808(aroE)
            LPF: lpl2723(aroE)
            LPP: lpp2854(aroE)
            LPC: LPC_3094(aroE)
            LPA: lpa_04080
            LLO: LLO_0262(aroE)
            MCA: MCA2794(aroE)
            FTU: FTT_0238(aroE1) FTT_0411c(aroE2)
            FTF: FTF0238(aroE1) FTF0411c(aroE2)
            FTW: FTW_1662 FTW_1853
            FTL: FTL_0173 FTL_0481
            FTH: FTH_0167(aroE1) FTH_0479(aroE2)
            FTA: FTA_0189(aroE) FTA_0507
            FTM: FTM_0567 FTM_1611
            FTN: FTN_0078(aroE) FTN_0511
            FPH: Fphi_0330 Fphi_0755
            TCX: Tcr_0153
            NOC: Noc_2575
            NHL: Nhal_3712
            NWA: Nwat_0544
            ALV: Alvin_3065
            AEH: Mlg_2825
            HHA: Hhal_1054
            TGR: Tgr7_0119
            TKM: TK90_2281
            HNA: Hneap_0694
            HCH: HCH_00037(aroE)
            CSA: Csal_0293 Csal_2862
            HEL: HELO_1380(aroE)
            ABO: ABO_0136(aroE)
            KKO: Kkor_0160
            MMW: Mmwyl1_0062 Mmwyl1_0070 Mmwyl1_3919
            AHA: AHA_0266(aroE)
            ASA: ASA_4132(aroE)
            TAU: Tola_0160(aroE) Tola_2080
            DNO: DNO_0509(aroE)
            AFE: Lferr_0361
            AFR: AFE_0182(aroE)
            BCI: BCI_0418(aroE)
            RMA: Rmag_0435(aroE)
            VOK: COSY_0405(aroE)
            GPB: HDN1F_00580(aroE)
            NMA: NMA2129
            NME: NMB0358(aroE)
            NMC: NMC1810(aroE)
            NMN: NMCC_1783(aroE)
            NMI: NMO_1682(aroE)
            NGO: NGO1602
            NGK: NGK_1905
            NLA: NLA_4190(aroE)
            CVI: CV_3587(aroE)
            LHK: LHK_01873(aroE)
            RSO: RSc2777(aroE) RSp1398(aroE)
            RSC: RCFBP_10684(aroE)
            RSL: RPSI07_0732(aroE) RPSI07_mp1386(aroE)
            RPI: Rpic_3021(aroE) Rpic_4302
            RPF: Rpic12D_2611(aroE) Rpic12D_4412
            REU: Reut_A2855(aroE) Reut_B5029
            REH: H16_A3161(aroE)
            RME: Rmet_3054(aroE)
            CTI: RALTA_A2636(aroE)
            BMA: BMA2494(aroE) BMAA0850(aroE)
            BMV: BMASAVP1_1754 BMASAVP1_A0414(aroE)
            BML: BMA10229_2208 BMA10229_A1274(aroE)
            BMN: BMA10247_3291(aroE) BMA10247_A0893
            BPS: BPSL2976(aroE) BPSS0341(aroE)
            BPM: BURPS1710b_3493(aroE) BURPS1710b_A1897(aroE)
            BPL: BURPS1106A_3496(aroE) BURPS1106A_A0483(aroE)
            BPD: BURPS668_3458(aroE) BURPS668_A0580(aroE)
            BPR: GBP346_A3640(aroE)
            BTE: BTH_I1171(aroE) BTH_II2057
            BVI: Bcep1808_0587(aroE) Bcep1808_3551 Bcep1808_4752
            BUR: Bcep18194_A3695(aroE) Bcep18194_B0345(aroE)
            BCN: Bcen_0130(aroE) Bcen_3064 Bcen_5532
            BCH: Bcen2424_0613(aroE) Bcen2424_5303 Bcen2424_5896
            BCM: Bcenmc03_0581(aroE) Bcenmc03_4965 Bcenmc03_6405
            BCJ: BCAL3413(aroE) BCAM2501(aroE) BCAS0366
            BAM: Bamb_0514(aroE) Bamb_4664 Bamb_5913 Bamb_6532
            BAC: BamMC406_0538(aroE) BamMC406_4665 BamMC406_5192 BamMC406_5799
                 BamMC406_6247
            BMU: Bmul_2772(aroE) Bmul_3420 Bmul_6127
            BMJ: BMULJ_00465(aroE) BMULJ_05108(aroE) BMULJ_05404(aroE)
            BXE: Bxe_A0539(aroE) Bxe_B0884 Bxe_C0879
            BPH: Bphy_2622(aroE) Bphy_6024 Bphy_6097 Bphy_6410
            BPY: Bphyt_3419(aroE) Bphyt_4569 Bphyt_5512 Bphyt_5792 Bphyt_6063
            BGL: bglu_1g05140(aroE) bglu_2g03870 bglu_2g09580
            BGE: BC1002_2675 BC1002_3347 BC1002_4264 BC1002_4378 BC1002_5625
            BRH: RBRH_03200
            PNU: Pnuc_0217
            PNE: Pnec_0238
            BPE: BP3004(aroE)
            BPA: BPP3924(aroE)
            BBR: BB4397(aroE)
            BPT: Bpet0567(aroE)
            BAV: BAV3004(aroE)
            AXY: AXYL_00612(aroE) AXYL_04856 AXYL_05925
            RFR: Rfer_3413(aroE)
            POL: Bpro_1087(aroE) Bpro_1847 Bpro_4495 Bpro_4503
            PNA: Pnap_1555 Pnap_1561 Pnap_1649 Pnap_2706 Pnap_3407(aroE)
            AAV: Aave_0841(aroE)
            AJS: Ajs_3656(aroE)
            DIA: Dtpsy_2966(aroE)
            VEI: Veis_2197(aroE)
            DAC: Daci_1482(aroE) Daci_4437
            VAP: Vapar_0935 Vapar_3325 Vapar_3329 Vapar_5700
            VPE: Varpa_0992 Varpa_2293 Varpa_2294
            CTT: CtCNB1_1926 CtCNB1_4102
            ADN: Alide_3683
            MPT: Mpe_A3201(aroE)
            HAR: HEAR2753(aroE)
            MMS: mma_2962(aroE)
            HSE: Hsero_0401(aroE) Hsero_3766(aroE)
            LCH: Lcho_0419 Lcho_1437 Lcho_2414(aroE) Lcho_2425 Lcho_3685
            TIN: Tint_2534
            NEU: NE1627(aroE1)
            NET: Neut_0496
            NMU: Nmul_A0538
            EBA: ebA1735(aroE)
            AZO: azo0707(aroE)
            DAR: Daro_3907
            TMZ: Tmz1t_3680(aroE)
            TBD: Tbd_2504
            MFA: Mfla_2445
            MMB: Mmol_2136
            MEH: M301_1630 M301_2548
            MEI: Msip34_2490
            MEP: MPQ_2436(aroE)
            APP: CAP2UW1_0285
            SLT: Slit_0482
            GCA: Galf_2091
            HPY: HP1249(aroE)
            HPJ: jhp1170(aroE)
            HPA: HPAG1_1192(aroE)
            HPS: HPSH_06470(aroE)
            HPG: HPG27_1194(aroE)
            HPP: HPP12_1215(aroE)
            HPB: HELPY_1225(aroE)
            HPL: HPB8_231(aroE)
            HPC: HPPC_06135(aroE)
            HPM: HPSJM_06245(aroE)
            HHE: HH1247(aroE)
            HAC: Hac_0244(aroE)
            HMS: HMU12570(aroE)
            HFE: Hfelis_10150(aroE)
            WSU: WS2168(aroE)
            TDN: Suden_1278(aroE)
            SKU: Sulku_1159
            CJE: Cj0405(aroE)
            CJR: CJE0454(aroE)
            CJJ: CJJ81176_0429(aroE)
            CJU: C8J_0380(aroE)
            CJN: ICDCCJ_369
            CJD: JJD26997_1552(aroE)
            CFF: CFF8240_1138(aroE)
            CCV: CCV52592_1353(aroE)
            CHA: CHAB381_1649(aroE)
            CCO: CCC13826_0229(aroE)
            CLA: Cla_0492(aroE)
            ABU: Abu_1073(aroE)
            ANT: Arnit_1865
            SDL: Sdel_0571
            NIS: NIS_1181(aroE)
            SUN: SUN_0470(aroE)
            NSA: Nitsa_0690
            NAM: NAMH_0904(aroE)
            GSU: GSU1490(aroE)
            GME: Gmet_1392
            GUR: Gura_2683
            GLO: Glov_1652
            GBM: Gbem_2596(aroE)
            GEO: Geob_3375
            GEM: GM21_1630
            PCA: Pcar_2150 Pcar_2192
            PPD: Ppro_2359
            DVU: DVU0115(aroE)
            DVL: Dvul_2848
            DVM: DvMF_1962
            DDE: Dde_3564
            DDS: Ddes_2096
            DMA: DMR_07350(aroE)
            DSA: Desal_3822
            DAS: Daes_3168
            DBA: Dbac_2724
            DRT: Dret_0088
            BBA: Bd1508(aroE)
            DPS: DP3012
            DAK: DaAHT2_0009
            DPR: Despr_0290
            DOL: Dole_3109
            DAL: Dalk_1761
            DAT: HRM2_22490(aroE1) HRM2_30830(aroE2)
            ADE: Adeh_0185
            ACP: A2cp1_0207
            AFW: Anae109_0205
            ANK: AnaeK_0196
            SCL: sce1639(aroE1) sce2226(aroE2) sce2476(aroE3)
            HOH: Hoch_6806
            SAT: SYN_01937
            SFU: Sfum_2721
            DBR: Deba_3217
            PUB: SAR11_0341(aroE)
            MLO: mlr4492(aroE)
            MCI: Mesci_0866 Mesci_2588
            MES: Meso_2294 Meso_3480(aroE) Meso_3972
            PLA: Plav_1254
            SME: SM_b20037(aroE) SMc02791(aroE)
            SMD: Smed_3211(aroE) Smed_5698
            RHI: NGR_b00200 NGR_b06000 NGR_b22730 NGR_c33520(aroE)
            ATU: Atu0003(aroE) Atu4295(aroE) Atu4532(aroE)
            ARA: Arad_0002(aroE) Arad_7777(aroEc) Arad_8808(aroEc)
            AVI: Avi_0004(aroE) Avi_5454(aroE)
            RET: RHE_CH00003(aroE) RHE_CH02291(aroEch2) RHE_PC00214(aroEc)
            REC: RHECIAT_CH0000004(aroE)
            RLE: RL0003(aroE) RL2845(aroE) RL2847 pRL110081
            RLT: Rleg2_3465 Rleg2_3937(aroE) Rleg2_5945 Rleg2_6263
            RLG: Rleg_4263(aroE) Rleg_7085
            BME: BMEI2058(aroE) BMEII0871
            BMI: BMEA_A2131(aroE) BMEA_B0036 BMEA_B0376
            BMF: BAB1_2070(aroE) BAB2_0033 BAB2_0825
            BMB: BruAb1_2044(aroE) BruAb2_0034 BruAb2_0804
            BMC: BAbS19_I19380(aroE) BAbS19_II00320 BAbS19_II07640
            BMS: BR2069(aroE) BRA0397
            BMT: BSUIS_A1910(aroE) BSUIS_B0036 BSUIS_B0400
            BOV: BOV_1989(aroE) BOV_A0031 BOV_A0340
            BCS: BCAN_A2115(aroE) BCAN_B0036 BCAN_B0400(aroE)
            BMR: BMI_I2091(aroE) BMI_II34 BMI_II394
            OAN: Oant_0851(aroE) Oant_4426
            BJA: bll1059(aroE) bll3660 bll6391(aroE) bll6392 bll7412(aroE)
                 blr2257(aroE) blr3543 blr3858
            BRA: BRADO0968 BRADO2346(aroE) BRADO5598(aroE) BRADO5961(aroE)
            BBT: BBta_1809(aroE) BBta_6119(aroE) BBta_7088
            RPA: RPA4325(aroE)
            RPB: RPB_1302
            RPC: RPC_4117
            RPD: RPD_3919
            RPE: RPE_4171
            RPT: Rpal_4803
            RPX: Rpdx1_4538
            NWI: Nwi_2977
            NHA: Nham_1109
            OCA: OCAR_7169(aroE)
            BHE: BH00030(aroE)
            BQU: BQ00030(aroE)
            BBK: BARBAKC583_0006(aroE)
            BTR: Btr_0003(aroE)
            BGR: Bgr_00030(aroE)
            XAU: Xaut_1616 Xaut_1829 Xaut_2703
            AZC: AZC_0003 AZC_1453
            SNO: Snov_3814
            MEX: Mext_1489
            MEA: Mex_1p1380
            MDI: METDI2150
            MRD: Mrad2831_0333 Mrad2831_4285
            MET: M446_1035 M446_4753(aroE)
            MPO: Mpop_1489
            MCH: Mchl_1767
            MNO: Mnod_0118 Mnod_0120(aroE) Mnod_1275 Mnod_3753 Mnod_5661
                 Mnod_8643
            BID: Bind_0104 Bind_3294 Bind_3572
            MSL: Msil_2537
            HDN: Hden_3272
            RVA: Rvan_2689
            CCR: CC_0003
            CCS: CCNA_00003
            CAK: Caul_0575 Caul_5013
            CSE: Cseg_4222
            PZU: PHZ_c0003(aroE)
            BSB: Bresu_0359
            AEX: Astex_0150
            SIL: SPO2425(aroE) SPO3891(aroE)
            SIT: TM1040_2860(aroE)
            RSP: RSP_1234(aroE)
            RSH: Rsph17029_2895(aroE)
            RSQ: Rsph17025_2671(aroE)
            RSK: RSKD131_2632(aroE)
            RCP: RCAP_rcc00068(aroE)
            JAN: Jann_0196(aroE)
            RDE: RD1_0438(aroE)
            PDE: Pden_2813(aroE) Pden_4664
            DSH: Dshi_3450(aroE)
            KVU: EIO_0027 EIO_2756(aroE)
            MMR: Mmar10_2976
            HNE: HNE_0003(aroE)
            HBA: Hbal_3146
            ZMO: ZMO0041
            ZMN: Za10_1136
            NAR: Saro_0115 Saro_1590
            SAL: Sala_2840
            SWI: Swit_2830
            SJP: SJA_C1-00030(aroE)
            ELI: ELI_12990
            GOX: GOX0859 GOX1959
            GBE: GbCGDNIH1_2144
            ACR: Acry_2761
            GDI: GDI_0015 GDI_2966(aroE)
            GDJ: Gdia_1772 Gdia_3384
            APT: APA01_08690
            RRU: Rru_A3613(aroE)
            RCE: RC1_2801(aroE)
            MAG: amb4547(aroE)
            AZL: AZL_000030(aroE) AZL_028730(aroE) AZL_c01580(aroE)
            PBR: PB2503_04377
            APB: SAR116_0098
            MGM: Mmc1_0022
            DIN: Selin_0249
            BSU: BSU25660(aroE)
            BSS: BSUW23_12730(aroD)
            BHA: BH1324(aroE)
            BAN: BA_4561(aroE)
            BAR: GBAA_4561(aroE)
            BAT: BAS4232(aroE)
            BAH: BAMEG_4597(aroE)
            BAI: BAA_4579(aroE)
            BAL: BACI_c43030(aroE)
            BCE: BC4331(aroE)
            BCA: BCE_4415(aroE)
            BCZ: BCZK4080(aroE)
            BCR: BCAH187_A4467(aroE)
            BCB: BCB4264_A4454(aroE)
            BCU: BCAH820_4356(aroE)
            BCG: BCG9842_B0783(aroE)
            BCQ: BCQ_4120(aroE)
            BCX: BCA_4445(aroE)
            BCY: Bcer98_3060(aroE)
            BTK: BT9727_4070(aroE)
            BTL: BALH_3922(aroE)
            BTB: BMB171_C3998(aroE)
            BWE: BcerKBAB4_4185(aroE)
            BLI: BL02079(aroE)
            BLD: BLi02759(aroE)
            BAY: RBAM_008060 RBAM_008070 RBAM_023960(aroE)
            BAO: BAMF_0755(RBAM_008070) BAMF_2464(aroD)
            BAE: BATR1942_01520 BATR1942_11150(aroE)
            BCL: ABC1638(aroD)
            BPU: BPUM_2300(aroE) BPUM_3656
            BPF: BpOF4_13235(aroE)
            BMQ: BMQ_0974(aroD) BMQ_4584(aroD)
            BMD: BMD_0975(aroD) BMD_4570(aroD)
            BSE: Bsel_2383
            BCO: Bcell_1568
            OIH: OB1987
            GKA: GK2524(aroE)
            GTN: GTNG_2460(aroE)
            GWC: GWCH70_2458(aroE)
            GYM: GYMC10_1710
            GYC: GYMC61_0993(aroE)
            GYA: GYMC52_2558
            GCT: GC56T3_0966
            GMC: GY4MC1_1041
            AFL: Aflv_0813(aroE)
            SAU: SA1424(aroE)
            SAV: SAV1596(aroE)
            SAW: SAHV_1583(aroE)
            SAH: SaurJH1_1688
            SAJ: SaurJH9_1653
            SAM: MW1547(aroE)
            SAS: SAS1533
            SAR: SAR1673(aroE)
            SAC: SACOL1652(aroE)
            SAX: USA300HOU_1597(aroE)
            SAA: SAUSA300_1555(aroE)
            SAO: SAOUHSC_01699
            SAE: NWMN_1498(aroE)
            SAD: SAAV_1587(aroE)
            SAB: SAB1468c(aroE)
            SEP: SE1282
            SER: SERP1163(aroE)
            SHA: SH1319(aroE)
            SSP: SSP1162
            SCA: Sca_1218(aroE)
            SLG: SLGD_01319
            SSD: SPSINT_1364
            LMO: lmo0490(aroE) lmo1490 lmo2236
            LMF: LMOf2365_0520(aroE) LMOf2365_1509(aroE-2) LMOf2365_2269
            LMH: LMHCC_0306 LMHCC_1080(aroE) LMHCC_2147(aroE)
            LMC: Lm4b_00513(aroE) Lm4b_01500 Lm4b_02263
            LMN: LM5578_0513(aroE) LM5578_1632 LM5578_2439
            LMY: LM5923_0512(aroE) LM5923_1584 LM5923_2390
            LIN: lin0493(aroE) lin1525 lin2338
            LWE: lwe0461(aroE) lwe1503(aroE) lwe2253
            LSG: lse_0405(aroE-1) lse_1405(aroE-2) lse_2216
            LSP: Bsph_3851
            ESI: Exig_0765
            EAT: EAT1b_2517
            MCL: MCCL_1245
            BBE: BBR47_19890(aroE)
            PJD: Pjdr2_4021
            PPY: PPE_00893 PPE_03242
            PPM: PPSC2_c0946 PPSC2_c3667
            AAC: Aaci_2016
            BTS: Btus_1206
            LLA: L0061(aroE)
            LLK: LLKF_1929(aroE)
            LLC: LACR_1921(aroE)
            LLM: llmg_1939(aroE)
            SPY: SPy_0534(aroE) SPy_1584(aroE)
            SPZ: M5005_Spy_0441(aroE) M5005_Spy_1303(aroE)
            SPM: spyM18_0600(aroE) spyM18_1592(aroE)
            SPG: SpyM3_0378(aroE) SpyM3_1284(aroE.1)
            SPS: SPs0577 SPs1475(aroE)
            SPH: MGAS10270_Spy0442(aroE) MGAS10270_Spy1418(aroE)
            SPI: MGAS10750_Spy0461(aroE) MGAS10750_Spy1412(aroE)
            SPJ: MGAS2096_Spy0460(aroE) MGAS2096_Spy1323(aroE)
            SPK: MGAS9429_Spy0440(aroE) MGAS9429_Spy1297(aroE)
            SPF: SpyM50552(aroE) SpyM51423(aroE)
            SPA: M6_Spy0475(aroE) M6_Spy1321
            SPB: M28_Spy0429(aroE) M28_Spy1344(aroE)
            SOZ: Spy49_0450(aroE) Spy49_1225c(aroE1)
            SPN: SP_1376(aroE)
            SPD: SPD_1210(aroE)
            SPR: spr1234(aroE)
            SPW: SPCG_1366(aroE)
            SPX: SPG_1317(aroE)
            SNE: SPN23F_13420(aroE)
            SPV: SPH_1508(aroE)
            SNM: SP70585_1415(aroE)
            SJJ: SPJ_1276(aroE)
            SPP: SPP_1396(aroE)
            SNT: SPT_0897(aroE)
            SNC: HMPREF0837_11172(aroE)
            SNB: SP670_0920(aroE)
            SNP: SPAP_1407
            SAG: SAG1680(aroE)
            SAN: gbs1724
            SAK: SAK_1692(aroE)
            SMU: SMU.778(aroE)
            SMC: SmuNN2025_1228(aroE)
            STC: str0639(aroE)
            STL: stu0639(aroE)
            STE: STER_0689(aroE)
            SSA: SSA_1469(aroE)
            SSU: SSU05_1251(aroE)
            SSV: SSU98_1266(aroE)
            SSB: SSUBM407_0701(aroE)
            SSI: SSU1088(aroE)
            SSS: SSUSC84_1121(aroE)
            SGO: SGO_1374(aroE)
            SEQ: SZO_04610
            SEZ: Sez_1495(aroE)
            SEU: SEQ_1681
            SUB: SUB1362(aroE)
            SDS: SDEG_1576(aroE)
            SGA: GALLO_1355(aroD)
            SMB: smi_0756(aroE)
            LPL: lp_1084(aroD1) lp_3494(aroE) lp_3498(aroD3) lp_3499(aroD4)
            LPJ: JDM1_0894(aroD1) JDM1_2786(aroE) JDM1_2789(aroD3)
                 JDM1_2790(aroD4)
            LPS: LPST_C0869(aroD1) LPST_C2864(aroE)
            LSA: LSA0892(aroE)
            LSL: LSL_1795(aroE)
            LCA: LSEI_0476 LSEI_0478(aroE)
            LCB: LCABL_05410(aroD4) LCABL_05430(aroE)
            LCZ: LCAZH_0506 LCAZH_0508
            LHE: lhv_1539
            LRH: LGG_00564(aroE) LGG_00566(aroE)
            EFA: EF1561(aroE)
            LME: LEUM_1168
            LCI: LCK_00697(aroE)
            LKI: LKI_09795
            LGS: LEGAS_1113(aroE)
            CAC: CA_C0897(aro)
            CPE: CPE0700(aroE)
            CPF: CPF_0693(aroE)
            CPR: CPR_0693(aroE)
            CTC: CTC01117
            CNO: NT01CX_0621(aroE)
            CTH: Cthe_0854
            CDF: CD1837(aroE) CD2708(ydiB)
            CDC: CD196_1757(aroE) CD196_2549(ydiB)
            CDL: CDR20291_1732(aroE) CDR20291_2596(ydiB)
            CBO: CBO2540
            CBA: CLB_2416(aroE)
            CBH: CLC_2398(aroE)
            CBY: CLM_2844(aroE)
            CBL: CLK_1923(aroE)
            CBK: CLL_A3139(aroE)
            CBB: CLD_2096(aroE)
            CBI: CLJ_B2770(aroE)
            CBT: CLH_0668(aroE) CLH_2889(aroE)
            CBF: CLI_2602(aroE)
            CBE: Cbei_4572
            CKL: CKL_0790(aroE1) CKL_1008(aroE) CKL_1014(aroE3)
            CKR: CKR_0707 CKR_0912(aroE) CKR_0918
            CPY: Cphy_2525
            CCE: Ccel_0663
            CLJ: CLJU_c28750(aroE1) CLJU_c29120(aroE2)
            CSH: Closa_2600
            CCB: Clocel_1279
            CST: CLOST_2376(aroE)
            AMT: Amet_1075
            AOE: Clos_0042
            STH: STH1952
            SWO: Swol_0524
            SLP: Slip_0395
            AFN: Acfer_0290 Acfer_1607
            DSY: DSY2394
            DHD: Dhaf_3537
            DRM: Dred_1018
            DAE: Dtox_2746
            PTH: PTH_1129(aroE)
            DAU: Daud_0987
            TJR: TherJR_1756
            HMO: HM1_0245(aroE)
            EEL: EUBELI_01327
            ERE: EUBREC_2843(aroE) EUBREC_2850
            ELM: ELI_0966
            EHA: Ethha_2653
            RAL: Rumal_0018
            TMR: Tmar_0219
            TTE: TTE1261(aroE)
            TEX: Teth514_1503
            TPD: Teth39_1066
            TIT: Thit_1055
            TMT: Tmath_1110
            TBO: Thebr_1093
            CHY: CHY_0623(aroE)
            MTA: Moth_1558
            ADG: Adeg_0656
            CSC: Csac_1055
            ATE: Athe_1889
            COB: COB47_1697
            CHD: Calhy_0895
            COW: Calow_1605
            CKI: Calkr_0811
            CKN: Calkro_0826
            TOC: Toce_1463
            TTM: Tthe_1276
            NTH: Nther_1732
            HOR: Hore_05960
            HAS: Halsa_1449
            AAR: Acear_1775
            ACL: ACL_0220(aroE)
            MTU: Rv2552c(aroE)
            MTC: MT2629(aroE)
            MRA: MRA_2581(aroE)
            MTF: TBFG_12573(aroE)
            MTB: TBMG_01420(aroE)
            MBO: Mb2582c(aroE)
            MBB: BCG_2575c(aroE)
            MBT: JTY_2569(aroE)
            MLE: ML0515(aroE)
            MLB: MLBr_00515(aroE)
            MPA: MAP1080(aroE)
            MAV: MAV_3428(aroE)
            MSM: MSMEG_3028(aroE) MSMEG_5457 MSMEG_6704
            MUL: MUL_1757(aroE)
            MVA: Mvan_2643(aroE) Mvan_4817
            MGI: Mflv_1916 Mflv_3760(aroE)
            MAB: MAB_2848c(aroE)
            MMC: Mmcs_2349(aroE) Mmcs_4283
            MKM: Mkms_2396(aroE) Mkms_4369
            MJL: Mjls_2390(aroE) Mjls_4662
            MSP: Mspyr1_13180 Mspyr1_31010
            MMI: MMAR_2173(aroE)
            CGL: NCgl0409(aroE) NCgl1087(aroE) NCgl1567(aroE)
            CGB: cg0504(aroE) cg1283(aroE) cg1835(aroE)
            CGT: cgR_0495 cgR_1216 cgR_1677(aroE)
            CEF: CE0443(aroE) CE1194(aroE) CE1745(aroE)
            CDI: DIP1006(aroE) DIP1347(aroE)
            CJK: jk1035(aroE)
            CUR: cur_0955
            CAR: cauri_1390(aroE)
            CKP: ckrop_1004
            CPU: cpfrc_00801 cpfrc_01147(aroE)
            NFA: nfa36410(aroE)
            RHA: RHA1_ro01342(aroE1) RHA1_ro01564(aroE2) RHA1_ro01853(aroE3)
                 RHA1_ro07138(aroE)
            RER: RER_29880(aroE) RER_38080 RER_39840 RER_46930
            ROP: ROP_10580(aroE) ROP_12660 ROP_15380(aroE) ROP_21990(aroE)
                 ROP_69190(aroE)
            REQ: REQ_17000(aroE) REQ_21540(aroE)
            GBR: Gbro_2323 Gbro_2789
            TPR: Tpau_1310 Tpau_1978
            SRT: Srot_1646
            SCO: SCO1498(aroE)
            SMA: SAV_1777(aroE) SAV_6853(aroE)
            SGR: SGR_6037(aroE)
            SCB: SCAB_12121 SCAB_15781(aroE) SCAB_75091(aroE)
            TWH: TWT373(aroE)
            TWS: TW396(aroE)
            LXX: Lxx00310(aroE) Lxx10940(aroE)
            CMI: CMM_1799(aroE)
            CMS: CMS_0732
            ART: Arth_2275 Arth_2889 Arth_3498 Arth_4080
            AAU: AAur_2278(aroE) AAur_2878(aroE) AAur_4046(aroE)
            ACH: Achl_2012 Achl_2599 Achl_3856
            AAI: AARI_17270(aroE) AARI_26000
            RSA: RSal33209_1678 RSal33209_1976
            KRH: KRH_13430(aroE)
            MLU: Mlut_12690
            RMU: RMDY18_00180 RMDY18_00530 RMDY18_09790
            RDN: HMPREF0733_10885(aroE) HMPREF0733_12001(aroE2)
            BCV: Bcav_2017
            BFA: Bfae_16330
            JDE: Jden_1348
            KSE: Ksed_12540
            XCE: Xcel_1693
            SKE: Sked_17730
            CFL: Cfla_1821
            ICA: Intca_1590
            PAC: PPA1181
            PAK: HMPREF0675_4242
            PFR: PFREUD_01580(aroE)
            NCA: Noca_2410
            KFL: Kfla_4369
            TFU: Tfu_2067
            NDA: Ndas_3072
            TCU: Tcur_2138
            SRO: Sros_6090
            FRA: Francci3_0433 Francci3_3211
            FRE: Franean1_1663 Franean1_1697 Franean1_7015 Franean1_7058
            FRI: FraEuI1c_1667
            FAL: FRAAL0918 FRAAL5249(aroE)
            ACE: Acel_1327
            NML: Namu_2895 Namu_3294 Namu_4100 Namu_5349
            GOB: Gobs_2247 Gobs_3155
            KRA: Krad_3029(aroE) Krad_3445
            SEN: SACE_2055(aroE) SACE_2867(rifI)
            SVI: Svir_15300(aroE)
            TBI: Tbis_2043
            AMD: AMED_0626(rifI) AMED_2716(aroE) AMED_4360(aroE)
            AMI: Amir_5262(aroE)
            STP: Strop_1831
            SAQ: Sare_1274 Sare_1822
            MAU: Micau_2321
            MIL: ML5_2433
            CAI: Caci_2381(aroE)
            SNA: Snas_3875 Snas_5094
            AHE: Arch_0913
            MCU: HMPREF0573_11724(aroE)
            BLO: BL0704(aroE)
            BLJ: BLD_0429(aroE)
            BLN: Blon_1084
            BLL: BLJ_1071
            BLB: BBMN68_396(aroE)
            BAD: BAD_0838(aroE)
            BLA: BLA_1369(aroE)
            BLC: Balac_0854
            BLT: Balat_0854
            BDE: BDP_1133
            BBI: BBIF_0985(aroE)
            BBP: BBPR_1041(aroE)
            GVA: HMPREF0424_0911
            GVG: HMPREF0421_20764(aroE)
            RXY: Rxyl_1362
            CWO: Cwoe_3037
            AFO: Afer_0954
            CCU: Ccur_12500
            SHI: Shel_06560
            ELE: Elen_2551
            CTR: CT370(aroDE)
            CTA: CTA_0402(aroDE)
            CTB: CTL0624(aroDE)
            CTL: CTLon_0622(aroDE)
            CTJ: JALI_3681(aroDE)
            CTZ: CTB_3681(aroDE)
            CMU: TC0649(aroDE)
            CPN: CPn1035(aroDE)
            CPA: CP0817(aroDE)
            CPJ: CPj1035(aroDE)
            CPT: CpB1075(aroDE)
            CCA: CCA00727(aroDE)
            CAB: CAB694(aroDE)
            CFE: CF0289(aroDE)
            WCH: wcw_1305(aroDE)
            SSM: Spirs_2853
            LIL: LA_0638(aroE)
            LIC: LIC12949(aroE)
            LBJ: LBJ_2329(aroE)
            LBL: LBL_0779(aroE)
            LBI: LEPBI_I0837(aroE)
            LBF: LBF_0806(aroE)
            BHY: BHWA1_01175(aroE)
            BRM: Bmur_2356
            BPO: BP951000_1374(aroE)
            ABA: Acid345_4110
            ACA: ACP_2227
            TSA: AciPR4_0897
            SUS: Acid_3092 Acid_3529 Acid_7159
            BTH: BT_4215
            BFR: BF0916
            BFS: BF0838(aroE)
            BVU: BVU_2541
            BHL: Bache_1413
            PGI: PG0978(aroE)
            PGN: PGN_0974
            PDI: BDI_1989
            PPN: Palpr_2801
            APS: CFPG_567
            PRU: PRU_0721
            PMZ: HMPREF0659_A6714
            SRU: SRU_2277(aroE)
            SRM: SRM_02503(aroE)
            RMR: Rmar_0148
            CHU: CHU_0006(aroE)
            DFE: Dfer_4321
            SLI: Slin_0705
            LBY: Lbys_3152
            MTT: Ftrac_1118 Ftrac_2672
            CPI: Cpin_1671
            PHE: Phep_4157
            GFO: GFO_0767(aroE)
            FJO: Fjoh_2589
            FPS: FP1769(aroE)
            COC: Coch_2085
            RBI: RB2501_01815
            ZPR: ZPR_1666
            CAT: CA2559_06730
            RAN: Riean_1659
            FBC: FB2170_09246
            CAO: Celal_2728
            FBA: FIC_01652
            SMG: SMGWSS_180(aroE)
            SMS: SMDSEM_184(aroE)
            SMH: DMIN_01750
            SUM: SMCARI_196(aroE)
            BBL: BLBBGE_142
            BPI: BPLAN_492(aroE)
            FSU: Fisuc_2245
            FNU: FN0044 FN0045
            LBA: Lebu_1670
            STR: Sterm_2373
            SMF: Smon_0743
            IPO: Ilyop_1867
            OTE: Oter_0500 Oter_3896
            CAA: Caka_0415
            MIN: Minf_2478(aroE)
            AMU: Amuc_1971
            GAU: GAU_1681(aroE)
            RBA: RB6488
            PSL: Psta_2225 Psta_4018
            PLM: Plim_1839
            IPA: Isop_0641
            RSD: TGRD_695
            TAI: Taci_1636
            SYN: slr1559(aroE)
            SYW: SYNW2509(aroE)
            SYC: syc1637_d(aroE)
            SYF: Synpcc7942_2467(aroE)
            SYD: Syncc9605_2675(aroE)
            SYE: Syncc9902_2304(aroE)
            SYG: sync_2924(aroE)
            SYR: SynRCC307_2518(aroE)
            SYX: SynWH7803_2515(aroE)
            SYP: SYNPCC7002_A1730(aroE)
            CYA: CYA_2729(aroE)
            CYB: CYB_1006(aroE)
            TEL: tll0590(aroE)
            MAR: MAE_37780(aroE)
            CYT: cce_4473(aroE)
            CYP: PCC8801_4417(aroE)
            CYC: PCC7424_0690(aroE)
            CYN: Cyan7425_2736(aroE)
            CYH: Cyan8802_4481(aroE)
            CYJ: Cyan7822_5300
            CYU: UCYN_12120
            GVI: gvip451(aroE)
            ANA: alr2057(aroE)
            NPU: Npun_R4233(aroE)
            AVA: Ava_3106(aroE)
            NAZ: Aazo_1154
            PMA: Pro1872(aroE)
            PMM: PMM1705(aroE)
            PMT: PMT2257(aroE)
            PMN: PMN2A_1314(aroE)
            PMI: PMT9312_1798(aroE)
            PMB: A9601_19151(aroE)
            PMC: P9515_18961(aroE)
            PMF: P9303_30051(aroE)
            PMG: P9301_18961(aroE)
            PMH: P9215_19781(aroE)
            PMJ: P9211_18411
            PME: NATL1_21871(aroE)
            TER: Tery_2187(aroE)
            AMR: AM1_3157(aroE)
            CTE: CT1809(aroE)
            CPC: Cpar_1649
            CCH: Cag_1345
            CPH: Cpha266_0708
            CPB: Cphamn1_1774
            CLI: Clim_1797
            PVI: Cvib_0539
            PLT: Plut_0483
            PPH: Ppha_2066
            PAA: Paes_1654
            CTS: Ctha_1609
            DET: DET0465(aroE)
            DEH: cbdb_A429(aroE)
            DEB: DehaBAV1_0442(aroE)
            DEV: DhcVS_408(aroE)
            DEG: DehalGT_0406
            DLY: Dehly_0222
            RRS: RoseRS_1564
            RCA: Rcas_3415
            CAU: Caur_1944
            CAG: Cagg_1838
            CHL: Chy400_2098
            HAU: Haur_4468
            TRO: trd_A0871(aroE)
            STI: Sthe_3266
            ATM: ANT_01900(aroE)
            DRA: DR_0077(aroE) DR_1173
            DGE: Dgeo_1192 Dgeo_1271 Dgeo_2374
            DDR: Deide_10210 Deide_10760(aroE) Deide_1p01400
            DMR: Deima_1561 Deima_2346
            TRA: Trad_0509 Trad_1640
            TTH: TTC0688
            TTJ: TTHA1050
            TSC: TSC_c09370(aroE)
            MRB: Mrub_1819
            MSV: Mesil_2226
            OPR: Ocepr_1052
            AAE: aq_901(aroE)
            HYA: HY04AAS1_1184
            HTH: HTH_1306(aroE)
            TAL: Thal_0975
            SUL: SYO3AOP1_1303
            SAF: SULAZ_1462(aroE)
            PMX: PERMA_1072(aroE)
            TAM: Theam_0140
            TMA: TM0346
            TPT: Tpet_0574
            TRQ: TRQ2_0589
            TNA: CTN_0325
            TNP: Tnap_0981
            PMO: Pmob_1201
            DTH: DICTH_0912(aroE)
            DTU: Dtur_1054
            TYE: THEYE_A0423(aroE)
            NDE: NIDE0446(aroE)
            TTR: Tter_0108
            DDF: DEFDS_1108(aroE)
            DAP: Dacet_1333
            CNI: Calni_1649
            MJA: MJ_1084(aroE)
            MFE: Mefer_1347(aroE)
            MVU: Metvu_0191(aroE)
            MFS: MFS40622_0173
            MIF: Metin_0656
            MMP: MMP0936(aroE)
            MMQ: MmarC5_0743(aroE)
            MMX: MmarC6_1719(aroE)
            MMZ: MmarC7_0183(aroE)
            MAE: Maeo_0450
            MVN: Mevan_0253(aroE)
            MVO: Mvol_0777
            MAC: MA4594(aroE)
            MBA: Mbar_A0923
            MMA: MM_1274
            MBU: Mbur_1998
            MMH: Mmah_0238
            MEV: Metev_1695
            MTP: Mthe_1501
            MHU: Mhun_1030
            MPD: MCP_0167(aroE)
            MMG: MTBMA_c06920(aroE)
            MST: Msp_0647(aroE)
            MSI: Msm_1179
            MRU: mru_1244(aroE)
            MFV: Mfer_1220
            MKA: MK0117(aroE)
            AFU: AF2327(aroE)
            APO: Arcpr_0877
            FPL: Ferp_0898
            HAL: VNG0382G(aroE)
            HSL: OE1565F(aroE)
            HMA: rrnAC0707(aroE)
            HWA: HQ1245A(aroE)
            NPH: NP0806A(aroE)
            HLA: Hlac_0456
            HUT: Huta_2478
            HMU: Hmuk_2932
            HTU: Htur_1368
            NMG: Nmag_2790
            HVO: HVO_0712(aroE2) HVO_0713(aroE1)
            HJE: HacjB3_12670
            HBO: Hbor_25040
            TAC: Ta0284(aroE)
            TVO: TVN1317(aroE)
            PTO: PTO0600(aroE)
            PAB: PAB0300(aroE)
            PFU: PF1693(aroE)
            TKO: TK0265(aroE)
            TON: TON_1136(aroE)
            TGA: TGAM_1595(aroE)
            TBA: TERMP_00423
            RCI: RCIX1312(aroE)
            APE: APE_0574.1(aroE)
            IHO: Igni_0215
            IAG: Igag_1734
            SSO: SSO0306(aroE)
            STO: ST2273
            SAI: Saci_0185(aroE)
            SIS: LS215_1936
            SIA: M1425_1796
            SIM: M1627_1914
            SID: M164_1844
            SIY: YG5714_1913
            SIN: YN1551_1012
            SII: LD85_2055
            MSE: Msed_1874
            PAI: PAE1913
            PIS: Pisl_1764
            PCL: Pcal_0880
            PAS: Pars_2118
            CMA: Cmaq_0805
            TNE: Tneu_0781
            VDI: Vdis_0217
            NMR: Nmar_0550
            CSY: CENSYa_0203
            KCR: Kcr_1090
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.25
            IUBMB Enzyme Nomenclature: 1.1.1.25
            ExPASy - ENZYME nomenclature database: 1.1.1.25
            BRENDA, the Enzyme Database: 1.1.1.25
            CAS: 9026-87-3
///
ENTRY       EC 1.1.1.26                 Enzyme
NAME        glyoxylate reductase;
            NADH-glyoxylate reductase;
            glyoxylic acid reductase;
            NADH-dependent glyoxylate reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     glycolate:NAD+ oxidoreductase
REACTION    glycolate + NAD+ = glyoxylate + NADH + H+ [RN:R00717]
ALL_REAC    R00717;
            (other) R01388
SUBSTRATE   glycolate [CPD:C00160];
            NAD+ [CPD:C00003]
PRODUCT     glyoxylate [CPD:C00048];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Reduces glyoxylate to glycolate or hydroxypyruvate to D-glycerate.
REFERENCE   1  [PMID:13061410]
  AUTHORS   ZELITCH I.
  TITLE     Oxidation and reduction of glycolic and glyoxylic acids in plants.
            II.  Glyoxylic acid reductase.
  JOURNAL   J. Biol. Chem. 201 (1953) 719-26.
  ORGANISM  Spinacia oleracea
REFERENCE   2  [PMID:13271335]
  AUTHORS   ZELITCH I.
  TITLE     The isolation and action of crystalline glyoxylic acid reductase
            from tobacco leaves.
  JOURNAL   J. Biol. Chem. 216 (1955) 553-75.
  ORGANISM  Nicotiana tabacum
PATHWAY     ec00630  Glyoxylate and dicarboxylate metabolism
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00015  glyoxylate reductase
GENES       HSA: 9380(GRHPR)
            CME: CMQ289C
            UMA: UM04061.1
            BPM: BURPS1710b_2926
            BPD: BURPS668_2809
            BUR: Bcep18194_A4216 Bcep18194_B1307
            BMJ: BMULJ_01041(gyaR)
            HAR: HEAR0804
            DAL: Dalk_2294
            DAT: HRM2_20310(gyaR)
            AFW: Anae109_1983
            PLA: Plav_2807 Plav_3643
            SMD: Smed_3380
            RLE: RL0145(gyaR) pRL110162(gyaR)
            RLT: Rleg2_4089
            RLG: Rleg_4409
            BCS: BCAN_A2219(gyaR)
            OAN: Oant_0734
            BJA: bll0766
            BRA: BRADO0066 BRADO3050
            BBT: BBta_0073 BBta_5085
            RPA: RPA0422
            RPB: RPB_0616
            RPC: RPC_0354
            RPD: RPD_0217
            RPE: RPE_0244
            NWI: Nwi_0037
            NHA: Nham_0045
            OCA: OCAR_4494
            XAU: Xaut_4126
            AZC: AZC_0236
            SNO: Snov_0241
            MEX: Mext_0421
            MEA: Mex_1p0336
            MDI: METDI0491
            MET: M446_2232
            MCH: Mchl_0454
            MNO: Mnod_0378
            BID: Bind_0511
            MSL: Msil_2485
            HDN: Hden_3510
            RVA: Rvan_2261
            CAK: Caul_5058
            CSE: Cseg_4172
            BSB: Bresu_0577
            SIT: TM1040_0480
            RSH: Rsph17029_0987
            RSQ: Rsph17025_2187
            RCP: RCAP_rcc00524(gyaR1)
            JAN: Jann_0915
            RDE: RD1_1164(gyaR) RD1_3437(gyaR) RD1_4247(gyaR)
            PDE: Pden_1941
            DSH: Dshi_2970(gyaR)
            HNE: HNE_3433(gyaR)
            HBA: Hbal_3053
            NAR: Saro_2308
            SAL: Sala_0778
            SWI: Swit_4583
            SJP: SJA_C1-23240
            RRU: Rru_A1815 Rru_A3790
            RCE: RC1_3133(gyaR)
            MAG: amb0195
            AZL: AZL_002190
            APB: SAR116_1568
            BMQ: BMQ_4977(gyaR)
            BMD: BMD_4963(gyaR)
            BSE: Bsel_1172
            GWC: GWCH70_2897
            GYC: GYMC61_3042
            GCT: GC56T3_0540
            LSP: Bsph_0853
            BTS: Btus_0385
            DHD: Dhaf_2820
            HMO: HM1_0770(gyaR)
            TTE: TTE1946(ldhA2)
            MSM: MSMEG_0604 MSMEG_2529 MSMEG_2550 MSMEG_6299
            RHA: RHA1_ro04923
            AAU: AAur_4149
            ACH: Achl_0089
            KRH: KRH_00410(gyaR)
            CWO: Cwoe_5009
            CYP: PCC8801_3049
            CYH: Cyan8802_3073
            CYJ: Cyan7822_2477
            AVA: Ava_4238
            PMG: P9301_12531
            RRS: RoseRS_0216
            RCA: Rcas_4324
            CAU: Caur_0825
            CAG: Cagg_2722
            CHL: Chy400_0891
            TRO: trd_0796
            STI: Sthe_1212
            MSV: Mesil_2536
            TLE: Tlet_1697
            TAF: THA_1150
            FNO: Fnod_1147
            NDE: NIDE2639(ghrB)
            TTR: Tter_0350
            PHO: PH0597
            PAB: PAB2374
            PFU: PF0319
            TKO: TK0683
            TON: TON_0945
            TGA: TGAM_1867(gyaR)
            TSI: TSIB_1280
            TBA: TERMP_01127
            ABI: Aboo_0052
            APE: APE_1265.1 APE_1831.1(gyaR) APE_2507.1
            IAG: Igag_0372
            HBU: Hbut_0860
            MSE: Msed_0256
            VDI: Vdis_2030
            TPE: Tpen_0823
            ASC: ASAC_0119
            NMR: Nmar_0412
            KCR: Kcr_1548
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.26
            IUBMB Enzyme Nomenclature: 1.1.1.26
            ExPASy - ENZYME nomenclature database: 1.1.1.26
            BRENDA, the Enzyme Database: 1.1.1.26
            CAS: 9028-32-4
///
ENTRY       EC 1.1.1.27                 Enzyme
NAME        L-lactate dehydrogenase;
            lactic acid dehydrogenase;
            L(+)-nLDH;
            L-(+)-lactate dehydrogenase;
            L-lactic dehydrogenase;
            L-lactic acid dehydrogenase;
            lactate dehydrogenase;
            lactate dehydrogenase NAD+-dependent;
            lactic dehydrogenase;
            NAD+-lactate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-lactate:NAD+ oxidoreductase
REACTION    (S)-lactate + NAD+ = pyruvate + NADH + H+ [RN:R00703]
ALL_REAC    R00703;
            (other) R01000 R03104
SUBSTRATE   (S)-lactate [CPD:C00186];
            NAD+ [CPD:C00003]
PRODUCT     pyruvate [CPD:C00022];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also oxidizes other (S)-2-hydroxymonocarboxylic acids. NADP+ also
            acts, more slowly, with the animal, but not the bacterial, enzyme.
REFERENCE   1  [PMID:13815938]
  AUTHORS   DENNIS D, KAPLAN NO.
  TITLE     D- and L-lactic acid dehydrogenases in Lactobacillus plantarum.
  JOURNAL   J. Biol. Chem. 235 (1960) 810-8.
  ORGANISM  Lactobacillus plantarum [GN:lpl]
REFERENCE   2  [PMID:4146647]
  AUTHORS   Adams MJ, Buehner M, Chandrasekhar K, Ford GC, Hackert ML, Liljas A,
            Rossmann MG, Smiley IE, Allison WS, Everse J, Kaplan NO, Taylor SS.
  TITLE     Structure-function relationships in lactate dehydrogenase.
  JOURNAL   Proc. Natl. Acad. Sci. U. S. A. 70 (1973) 1968-72.
  ORGANISM  Squalus acanthius
REFERENCE   3
  AUTHORS   Holbrook, J.J., Liljas, A., Steindel, S.J. and Rossmann, M.G.
  TITLE     Lactate dehydrogenase.
  JOURNAL   In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 11, Academic
            Press, New York, 1975, p. 191-292.
REFERENCE   4  [PMID:114469]
  AUTHORS   Schar HP, Zuber H.
  TITLE     Structure and function of L-lactate dehydrogenases from thermophilic
            and mesophilic bacteria. I) Isolation and characterization of
            lactate dehydrogenases from thermophilic and mesophilic bacilli.
  JOURNAL   Hoppe. Seylers. Z. Physiol. Chem. 360 (1979) 795-807.
  ORGANISM  Bacillus subtilis [GN:bsu], Bacillus stearothermophilus, Bacillus
            caldotenax
PATHWAY     ec00010  Glycolysis / Gluconeogenesis
            ec00270  Cysteine and methionine metabolism
            ec00620  Pyruvate metabolism
            ec00640  Propanoate metabolism
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00016  L-lactate dehydrogenase
GENES       HSA: 160287(LDHAL6A) 3939(LDHA) 3945(LDHB) 3948(LDHC) 92483(LDHAL6B)
            PTR: 451063(LDHA) 451064(LDHC) 464999 465337(LDHB) 466460(LDHAL6A)
                 747141(LDHAL6B)
            PON: 100173786(LDHA) 100439283(LDHAL6B) 100443907 100453251(LDHB)
            MCC: 693731(LDHC) 693802(LDHB) 693907 694309(LDHA) 696854(LDHA)
                 696935(LDHB) 702403(LDHAL6B) 706110(LDHB) 716800(LDHB)
                 718082(LDHB)
            MMU: 106557(Ldhal6b) 16828(Ldha) 16832(Ldhb) 16833(Ldhc)
                 433229(Gm5514)
            RNO: 24533(Ldha) 24534(Ldhb) 29634(Ldhc) 369018(Ldhal6b)
                 500965(RGD1562690)
            CFA: 475101 476213 476882(LDHA) 476883(LDHC) 477675(LDHB) 477883
                 479371 481004 482405 484048(LDHAL6B) 485449 490690 609013
                 610330 611702
            AML: 100469967 100472134 100472384 100483734
            BTA: 281274(LDHA) 281275(LDHB) 509519(LDHAL6B) 784938(LDHA)
            SSC: 100153697 100502559(LDHC) 407245(LDHA) 407246(LDHB)
            ECB: 100033997(LDHB) 100057016(LDHA) 100057054 100059970
            MDO: 100012604 100016009 100023295 100028279 100028290 503513(LDHA)
                 554182(LDHB)
            OAA: 100086588 791112(LDHA)
            GGA: 373997(LDHB) 396221(LDHA)
            TGU: 100190454(LDHB) 100223914
            XLA: 380394(ldha-a) 380546(ldhb-a) 394355(ldhb-b) 398121(ldha-b)
            XTR: 394477(ldhb) 394758(ldha)
            DRE: 30496(ldha) 30497(ldhba) 436747(ldhbb)
            CIN: 100174998
            SPU: 586683
            DME: Dmel_CG10160(ImpL3) Dmel_CG13334
            DPO: Dpse_GA10121 Dpse_GA24202
            DAN: Dana_GF10902 Dana_GF13705
            DER: Dere_GG14061 Dere_GG20393
            DPE: Dper_GL17466
            DSE: Dsec_GM13843 Dsec_GM21480
            DSI: Dsim_GD10977 Dsim_GD13128
            DWI: Dwil_GK15970 Dwil_GK17340
            DYA: Dyak_GE12554 Dyak_GE20486
            DGR: Dgri_GH16279
            DMO: Dmoj_GI13222
            DVI: Dvir_GJ11996 Dvir_GJ17738
            AGA: AgaP_AGAP004880
            AAG: AaeL_AAEL012014
            CQU: CpipJ_CPIJ014454 CpipJ_CPIJ016131
            AME: 411188
            NVI: 100118743(NV16814)
            TCA: 656589
            PHU: Phum_PHUM581610
            CEL: F13D12.2(ldh-1)
            CBR: CBG03136(Cbr-ldh-1)
            BMY: Bm1_43730
            SMM: Smp_038950 Smp_038960
            ATH: AT4G17260
            POP: POPTR_554197
            RCU: RCOM_0540790 RCOM_0540800
            VVI: 100248878 100250615
            OSA: 4328012 4339856
            SBI: SORBI_04g000580 SORBI_04g000590
            ZMA: 100193279 100282503(cl2158_1)
            PPP: PHYPADRAFT_146489 PHYPADRAFT_195311 PHYPADRAFT_55784
            CME: CMA145C CMC188C CMI306C CMJ002C CMK006C
            LTH: KLTH0D00440g KLTH0G19558g
            NCR: NCU00720
            PAN: PODANSg09793 PODANSg866
            MGR: MGG_10453(MG10453.4)
            FGR: FG10444.1
            ANI: AN5842.2
            AFM: AFUA_5G14800
            ANG: An04g08220
            ACT: ACLA_004370
            PNO: SNOG_10492
            SPO: SPAC186.08c
            MBR: MONBRDRAFT_32392
            PFA: PF13_0141(PfLDH)
            ECG: E2348C_4376
            ECC: c5039
            ECP: ECP_4280
            ECI: UTI89_C4637
            ECV: APECO1_2404
            ECZ: ECS88_4540
            EFE: EFER_4154
            ENT: Ent638_2002
            ESA: ESA_01812
            CTU: Ctu_21690(ldh2)
            KPN: KPN_01632
            KPE: KPK_2747
            KPU: KP1_2672
            KVA: Kvar_2702
            CKO: CKO_01547 CKO_03848
            VVU: VV2_1457
            VVY: VVA0276
            VVM: VVM_00528
            VPA: VPA0147
            VEX: VEA_000852
            TTU: TERTU_0352
            TGR: Tgr7_1919
            TAU: Tola_1750
            REH: H16_A0666(ldh)
            RME: Rmet_0559
            BGL: bglu_2g19240
            BGE: BC1002_3504
            BPE: BP0379(ldh)
            BPA: BPP4051(ldh)
            BBR: BB4524(ldh) BB4684
            BAV: BAV3171(ldh)
            AXY: AXYL_06161
            VEI: Veis_4538
            CJE: Cj1167(ldh)
            CJR: CJE1301(ldh)
            CJJ: CJJ81176_1182(ldh)
            CJU: C8J_1111(ldh)
            CJN: ICDCCJ_1120
            CJD: JJD26997_0565
            ANT: Arnit_1568
            SDL: Sdel_0325
            GEO: Geob_0424
            DVU: DVU0600(ldh)
            DVL: Dvul_2352
            SCL: sce5245(ldh)
            AVI: Avi_4103(mdh)
            RLE: pRL120231
            RCP: RCAP_rcc00817(ldh)
            RCE: RC1_3506
            AZL: AZL_026880(ldh)
            BSU: BSU03050(ldh)
            BSS: BSUW23_01560(ldh)
            BHA: BH3937(lctE)
            BAN: BA_1923(ldh) BA_5125(ldh) BA_5240(ldh)
            BAR: GBAA_1923(ldh) GBAA_5125(ldh) GBAA_5240(ldh)
            BAT: BAS1784(ldh) BAS4762(ldh) BAS4869(ldh)
            BAH: BAMEG_2667(ldh) BAMEG_5157(ldh) BAMEG_5294(ldh)
            BAI: BAA_1993(ldh) BAA_5136(ldh) BAA_5272(ldh)
            BAL: BACI_c19060(ldh1) BACI_c48760(ldh2) BACI_c50080(ldh3)
            BCE: BC1924(ldh) BC4870(ldh) BC4996(ldh)
            BCA: BCE_2007(ldh) BCE_5032(ldh) BCE_5135(ldh)
            BCZ: BCZK1741(ldh) BCZK4624(ldh) BCZK4723(ldh)
            BCR: BCAH187_A2028(ldh) BCAH187_A5012(ldh) BCAH187_A5142(ldh)
            BCB: BCB4264_A1927(ldh) BCB4264_A5002(ldh) BCB4264_A5140(ldh)
            BCU: BCAH820_1959(ldh) BCAH820_4981(ldh) BCAH820_5106(ldh)
            BCG: BCG9842_B0100(ldh) BCG9842_B0236(ldh) BCG9842_B3415(ldh)
            BCQ: BCQ_4689(ldh) BCQ_4814(ldh)
            BCX: BCA_1989(ldh) BCA_5005(ldh) BCA_5136(ldh)
            BCY: Bcer98_1484(ldh) Bcer98_3505(ldh) Bcer98_3591(ldh)
            BTK: BT9727_1763(ldh) BT9727_4600(ldh) BT9727_4708(ldh)
            BTL: BALH_1702(ldh) BALH_4435(ldh) BALH_4532(ldh)
            BTB: BMB171_C1712(ldh) BMB171_C4509(ldh) BMB171_C4605(ldh)
            BWE: BcerKBAB4_1798(ldh) BcerKBAB4_4713(ldh) BcerKBAB4_4826(ldh)
            BLI: BL01703(ldh)
            BLD: BLi00366(ldh)
            BAY: RBAM_003290(ldh)
            BAO: BAMF_0277(ldh)
            BAE: BATR1942_20165(ldh)
            BCL: ABC2872(ldh)
            BPU: BPUM_0277(ldh)
            BPF: BpOF4_04835(ldh)
            BMQ: BMQ_0521(ldh)
            BMD: BMD_0524(ldh)
            BSE: Bsel_2311
            BCO: Bcell_1656
            OIH: OB3279
            GKA: GK0475(ldh)
            GTN: GTNG_0487(ldh)
            GWC: GWCH70_0489(ldh)
            GYM: GYMC10_3602
            GYC: GYMC61_1361(ldh)
            GYA: GYMC52_0482
            GCT: GC56T3_2991
            GMC: GY4MC1_3298
            AFL: Aflv_0889(ldh)
            SAU: SA0232(lctE) SA2395
            SAV: SAV0241(lctE) SAV2602
            SAW: SAHV_0240(lctE) SAHV_2586
            SAH: SaurJH1_0231 SaurJH1_2678
            SAJ: SaurJH9_0225 SaurJH9_2624
            SAM: MW0217(lctE) MW2521
            SAS: SAS0217 SAS2487
            SAR: SAR0234(ldh1) SAR2680(ldh2)
            SAC: SACOL0222(ldh1) SACOL2618(ldh2)
            SAX: USA300HOU_0251(ldh)
            SAA: SAUSA300_0235 SAUSA300_2537
            SAO: SAOUHSC_00206 SAOUHSC_02922
            SAE: NWMN_0176(ldh1) NWMN_2499(ldh)
            SAD: SAAV_0206(ldh1) SAAV_2668(ldh2)
            SAB: SAB0180 SAB2475c(ldh)
            SEP: SE2145
            SER: SERP2156(ldh)
            SHA: SH0525
            SSP: SSP0249 SSP1001
            SCA: Sca_0343(ldh) Sca_1369(ldh)
            SLG: SLGD_00048 SLGD_00459
            SSD: SPSINT_1529 SPSINT_2058
            LMO: lmo0210(ldh) lmo1534 lmo1667
            LMF: LMOf2365_0221(ldh) LMOf2365_1553(ldh-2) LMOf2365_1691
            LMH: LMHCC_0899 LMHCC_1035 LMHCC_2433(ldh)
            LMC: Lm4b_00208(ldh) Lm4b_01077 Lm4b_01544 Lm4b_01680
            LMN: LM5578_1814 LM5578_2808(ldh)
            LMY: LM5923_1766 LM5923_2757(ldh)
            LIN: lin0242(ldh) lin1569 lin1775
            LWE: lwe0172(ldh) lwe1034 lwe1547(ldhB) lwe1685
            LSG: lse_0196(ldh-1) lse_1449(ldh-2) lse_1635
            ESI: Exig_0870
            EAT: EAT1b_0554
            MCL: MCCL_0163(lctD) MCCL_0255
            PJD: Pjdr2_5353
            PPY: PPE_00452 PPE_02467
            PPM: PPSC2_c0485 PPSC2_c2820
            AAC: Aaci_0520
            LLA: L0017(ldh) L0018(ldhB) L142159(ldhX)
            LLK: LLKF_0427(ldhB) LLKF_0494 LLKF_1154(ldhX) LLKF_1422(ldhL)
            LLC: LACR_0421 LACR_1239 LACR_1455(ldh)
            LLM: llmg_0392(ldhB) llmg_1120(ldh) llmg_1429(ldhX)
            SPY: SPy_1151(ldh)
            SPZ: M5005_Spy_0873(ldh)
            SPM: spyM18_1111(ldh)
            SPG: SpyM3_0809(ldh)
            SPS: SPs1008(ldh)
            SPH: MGAS10270_Spy0987(ldh)
            SPI: MGAS10750_Spy1022(ldh)
            SPJ: MGAS2096_Spy0947(ldh)
            SPK: MGAS9429_Spy0991(ldh)
            SPF: SpyM50917(ldh)
            SPA: M6_Spy0869(ldh)
            SPB: M28_Spy0847(ldh)
            SOZ: Spy49_0904c(ldh)
            SPN: SP_1220(ldh)
            SPD: SPD_1078(ldh)
            SPR: spr1100(ldh)
            SPW: SPCG_1081(ldh)
            SPX: SPG_1112(ldh)
            SNE: SPN23F_11170(ldh)
            SPV: SPH_1335(ldh)
            SNM: SP70585_1267(ldh)
            SJJ: SPJ_1135(ldh)
            SPP: SPP_1258(ldh)
            SNT: SPT_1008(ldh)
            SNC: HMPREF0837_11282(ldh)
            SNB: SP670_1059
            SNP: SPAP_1246
            SAG: SAG0128 SAG0959(ldh)
            SAN: gbs0126 gbs0947(ldh)
            SAK: SAK_0179 SAK_1054(ldh)
            SMU: SMU.1115(ldh)
            SMC: SmuNN2025_0926(ldh)
            STC: str0644(hdhL) str1280(ldh)
            STL: stu0644(hdhL) stu1280(ldh)
            STE: STER_0694 STER_1257(ldh)
            SSA: SSA_1221(ldh)
            SSU: SSU05_1076(ldh)
            SSV: SSU98_1087(ldh)
            SSB: SSUBM407_0854(ldh)
            SSI: SSU0927(ldh)
            SSS: SSUSC84_0970(ldh)
            SGO: SGO_1232(ldh) SGO_1369
            SEQ: SZO_09420(ldh)
            SEZ: Sez_1022(ldh)
            SEU: SEQ_1169(ldh)
            SUB: SUB0879(ldh)
            SDS: SDEG_0911(ldh)
            SGA: GALLO_1350
            SMB: smi_1006(ldh)
            LPL: lp_0537(ldhL1) lp_1101(ldh) lp_1245(hicD2) lp_2349(hicD3)
            LPJ: JDM1_0436(ldhL1) JDM1_0908(ldh) JDM1_1054(hicD2)
                 JDM1_1964(hicD3)
            LPS: LPST_C0295(hicD1) LPST_C0446(ldhL1) LPST_C0882(ldh)
                 LPST_C1010(hicD2) LPST_C1952(hicD3)
            LJO: LJ0274 LJ1403(ldh)
            LJF: FI9785_1528(hicD) FI9785_337(ldh) FI9785_863(ldh)
            LAC: LBA0271 LBA0910(ldh) LBA1516
            LSA: LSA1606(ldh)
            LSL: LSL_1362(ldh)
            LDB: Ldb0120(ldh)
            LBU: LBUL_0100(ldh)
            LDE: LDBND_0067 LDBND_0089(ldh)
            LBR: LVIS_0514
            LCA: LSEI_0634 LSEI_2549 LSEI_2607
            LCB: LCABL_06930(ldh) LCABL_27160(ldh) LCABL_27730(hicD3)
            LCZ: LCAZH_0554 LCAZH_2512 LCAZH_2572
            LGA: LGAS_0269 LGAS_0849(ldh)
            LRE: Lreu_0194 Lreu_0716 Lreu_0907 Lreu_1272
            LRF: LAR_0185 LAR_0688 LAR_0853 LAR_1206
            LHE: lhv_0289 lhv_0978(ldh) lhv_1578
            LFE: LAF_0348 LAF_0806
            LRH: LGG_00606(ldh) LGG_02523(ldh) LGG_02591(hicD)
            LRL: LC705_00585(ldh) LC705_02527(ldh) LC705_02599(hicD)
            LCR: LCRIS_00274(ldh1) LCRIS_00963(ldh2) LCRIS_01483(ldh3)
            LAM: LA2_01445 LA2_04745(ldh) LA2_08490
            PPE: PEPE_1554
            EFA: EF0255(ldh) EF0641(ldh-2)
            LCI: LCK_01655
            LKI: LKI_06135
            LGS: LEGAS_1815
            CAC: CA_C0267(ldh) CA_C3552
            CPE: CPE0103(ldh)
            CPF: CPF_0098(ldh)
            CPR: CPR_0102(ldh)
            CTC: CTC01998(ldh)
            CNO: NT01CX_0236(ldh)
            CTH: Cthe_1053(ldh)
            CDF: CD2164(ldh)
            CDC: CD196_2027(ldh)
            CDL: CDR20291_2070(ldh)
            CBO: CBO1519(ldh)
            CBA: CLB_1540(ldh)
            CBH: CLC_1552(ldh)
            CBY: CLM_1754(ldh)
            CBL: CLK_0997(ldh)
            CBK: CLL_A2569 CLL_A3511
            CBB: CLD_3035(ldh)
            CBI: CLJ_B1617(ldh)
            CBT: CLH_2335 CLH_3305
            CBF: CLI_1599(ldh)
            CBE: Cbei_1014 Cbei_2789 Cbei_4903
            CKL: CKL_1381
            CKR: CKR_1277
            CPY: Cphy_1117 Cphy_1232
            CCE: Ccel_2485(ldh)
            CSH: Closa_1306
            CCB: Clocel_1533 Clocel_2700
            VPR: Vpar_0498
            AFN: Acfer_1037
            DRM: Dred_2797
            PTH: PTH_0747(mdh)
            DAU: Daud_1522
            TJR: TherJR_0751
            HMO: HM1_2756(ldh)
            APR: Apre_1065
            EEL: EUBELI_20026
            ERE: EUBREC_2331
            EHA: Ethha_1350 Ethha_2705
            CLO: HMPREF0868_0218
            TEX: Teth514_0216
            TPD: Teth39_1997
            TIT: Thit_0237
            TMT: Tmath_0320
            TBO: Thebr_2046
            MTA: Moth_1826
            ADG: Adeg_1582
            CSC: Csac_1027
            ATE: Athe_1918
            COB: COB47_1726
            CHD: Calhy_0866
            COW: Calow_1634
            CKI: Calkr_0782
            CKN: Calkro_0797
            TOC: Toce_1441
            TTM: Tthe_2412
            HOR: Hore_16140
            HAS: Halsa_1287
            AAR: Acear_0295
            MGE: MG_460(ldh)
            MPN: MPN674(ldh)
            MPU: MYPU_7590(ldh)
            MPE: MYPE9640
            MGA: MGA_0746(ldh)
            MMY: MSC_0532(ldh)
            MMO: MMOB0410(ldh)
            MHY: mhp245(ictD) mhp469(ldh)
            MHJ: MHJ_0133(ldh) MHJ_0468
            MHP: MHP7448_0137(ldh) MHP7448_0471
            MSY: MS53_0461(ldh)
            MCP: MCAP_0439(ldh)
            MAA: MAG_4900(ldh)
            MAL: MAGa5370(ldh)
            MAT: MARTH_orf109(ldh)
            MCO: MCJ_001000 MCJ_006130(ldh)
            MHO: MHO_3580(ldh)
            MHR: MHR_0023(ldh) MHR_0431(ldh)
            MBV: MBOVPG45_0326(ldh)
            MLC: MSB_A0453
            ACL: ACL_1028(ldh)
            MFL: Mfl596
            MVA: Mvan_0439
            MGI: Mflv_0307
            MMC: Mmcs_0382
            MKM: Mkms_0391
            MJL: Mjls_0370
            MSP: Mspyr1_04500
            CGL: NCgl2810(ldh)
            CGB: cg3219(ldh)
            CGT: cgR_2812(ldh)
            CEF: CE2753(ldh)
            CDI: DIP0427 DIP2255(ldh)
            CJK: jk0113(ldh)
            CAR: cauri_2403(ldh)
            CKP: ckrop_0111(ldh) ckrop_1700
            CPU: cpfrc_00300(ldhA) cpfrc_01996(ldhB)
            RER: RER_42180(ldh)
            GBR: Gbro_1116
            SMA: SAV_339(ldhA)
            ART: Arth_3978
            KRH: KRH_05010(ldh)
            MLU: Mlut_21510
            RDN: HMPREF0733_11916(mdh)
            BCV: Bcav_2434
            JDE: Jden_1053
            XCE: Xcel_1257
            SKE: Sked_23050
            CFL: Cfla_1564
            ICA: Intca_3315
            PAC: PPA0012 PPA0887 PPA1952
            PAK: HMPREF0675_3011 HMPREF0675_3945 HMPREF0675_5012
            PFR: PFREUD_11570(ldh1) PFREUD_12840(ldh2)
            NML: Namu_0206
            AHE: Arch_1453
            BLO: BL0710(ldh1) BL1308(ldh2)
            BLJ: BLD_0165(ldh) BLD_0435
            BLN: Blon_0840 Blon_1090
            BLL: BLJ_1065 BLJ_1311
            BLB: BBMN68_193(ldh) BBMN68_402
            BAD: BAD_1117(ldh2)
            BLA: BLA_0305(ldh) BLA_0792
            BLC: Balac_0321 Balac_1214
            BLT: Balat_0321 Balat_1214
            BBI: BBIF_0564(ldh2) BBIF_0979(ldh3)
            BBP: BBPR_0539(ldh) BBPR_1035(ldhL)
            GVA: HMPREF0424_0663
            GVG: HMPREF0421_20527(ldh2) HMPREF0421_20719(ldh1)
            APV: Apar_0054
            ELE: Elen_2253
            OLS: Olsu_0043
            BBU: BB0087
            BBZ: BbuZS7_0087
            BGA: BG0088(ldh)
            BAF: BAPKO_0088(ldh)
            BTU: BT0087
            BHR: BH0087
            BDU: BDU_90(ldh)
            BRE: BRE_89(ldh)
            TDE: TDE0351(ldh)
            LIL: LA_1488(lldD)
            BHY: BHWA1_01750(ldh)
            BRM: Bmur_1505
            BPO: BP951000_2248(ldh)
            ABA: Acid345_1483
            SRU: SRU_0681
            SRM: SRM_00857(ldh)
            RMR: Rmar_0132
            FNU: FN1169
            STR: Sterm_2675
            SMF: Smon_0985
            OTE: Oter_1299
            RBA: RB2566(ldh) RB856(ldh)
            PSL: Psta_3289
            PLM: Plim_1203 Plim_1746
            IPA: Isop_1634
            CYA: CYA_2670
            CYB: CYB_2165
            MAR: MAE_05340
            CYT: cce_5187(ldh)
            CYC: PCC7424_3778
            CYJ: Cyan7822_4413
            GVI: gll3324
            NPU: Npun_R1983
            AMR: AM1_5026(ldh)
            CTS: Ctha_2381
            CAU: Caur_1675
            CAG: Cagg_2397
            CHL: Chy400_1816
            ATM: ANT_16210(ldh)
            DRA: DR_2364
            DDR: Deide_22290(ldh)
            DMR: Deima_3081
            TTH: TTC0748
            TTJ: TTHA1113
            TMA: TM1867
            TPT: Tpet_0930
            TLE: Tlet_1246
            TRQ: TRQ2_0952
            TNA: CTN_0802
            TNP: Tnap_0624
            TAF: THA_1478
            FNO: Fnod_1175
            PMO: Pmob_1893
            KOL: Kole_0912
            DTH: DICTH_0539
            DTU: Dtur_0700
            HUT: Huta_0463
            HVO: HVO_0214
            HJE: HacjB3_00765
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.27
            IUBMB Enzyme Nomenclature: 1.1.1.27
            ExPASy - ENZYME nomenclature database: 1.1.1.27
            BRENDA, the Enzyme Database: 1.1.1.27
            CAS: 9001-60-9
///
ENTRY       EC 1.1.1.28                 Enzyme
NAME        D-lactate dehydrogenase;
            lactic acid dehydrogenase;
            lactic acid dehydrogenase;
            D-specific lactic dehydrogenase;
            D-(-)-lactate dehydrogenase (NAD+);
            D-lactic acid dehydrogenase;
            D-lactic dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-lactate:NAD+ oxidoreductase
REACTION    (R)-lactate + NAD+ = pyruvate + NADH + H+ [RN:R00704]
ALL_REAC    R00704
SUBSTRATE   (R)-lactate [CPD:C00256];
            NAD+ [CPD:C00003]
PRODUCT     pyruvate [CPD:C00022];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13815938]
  AUTHORS   DENNIS D, KAPLAN NO.
  TITLE     D- and L-lactic acid dehydrogenases in Lactobacillus plantarum.
  JOURNAL   J. Biol. Chem. 235 (1960) 810-8.
  ORGANISM  Lactobacillus plantarum [GN:lpl]
PATHWAY     ec00620  Pyruvate metabolism
ORTHOLOGY   K03777  D-lactate dehydrogenase
            K03778  D-lactate dehydrogenase
GENES       NCR: NCU00780
            MGR: MGG_08725(MG08725.4)
            FGR: FG09696.1
            ANI: AN0628.2
            AFM: AFUA_1G17040
            NFI: NFIA_008330
            AOR: AO090023000577
            ANG: An01g09780
            AFV: AFLA_109930
            ACT: ACLA_018480
            PCS: Pc21g23650
            CNE: CNA08110
            CNB: CNBA7930
            TET: TTHERM_01014570
            PTM: GSPATT00008304001
            ECO: b1380(ldhA) b2133(dld)
            ECJ: JW1375(ldhA) JW2121(dld)
            ECD: ECDH10B_1505(ldhA) ECDH10B_2289(dld)
            EBW: BWG_1209(ldhA) BWG_1917(dld)
            ECE: Z2329(ldhA) Z3382(dld)
            ECS: ECs2002 ECs3020
            ECF: ECH74115_2002(idhA) ECH74115_3259(dld)
            ETW: ECSP_1878(ldhA) ECSP_3005(dld)
            EOJ: ECO26_1984(ldhA) ECO26_3046(dld)
            EOI: ECO111_1773(ldhA) ECO111_2851(dld)
            EOH: ECO103_1516(ldhA) ECO103_2609(dld)
            ECG: E2348C_1542(ldhA) E2348C_2280(dld)
            EOK: G2583_1757(ldhA) G2583_2670(dld)
            ECC: c1827(ldhA) c2664(dld)
            ECP: ECP_1406 ECP_2172
            ECI: UTI89_C1623(ldhA) UTI89_C2407(dld)
            ECV: APECO1_4416(dld) APECO1_554(ldhA)
            ECX: EcHS_A1467(idhA) EcHS_A2268(dld)
            ECW: EcE24377A_1565(idhA) EcE24377A_2423(dld)
            ECM: EcSMS35_0911(dld) EcSMS35_1771(idhA)
            ECY: ECSE_1465 ECSE_2401
            ECR: ECIAI1_1380(ldhA) ECIAI1_2211(dld)
            ECQ: ECED1_1564(ldhA) ECED1_2577(dld)
            ECK: EC55989_1516(ldhA) EC55989_2383(dld)
            ECT: ECIAI39_0863(dld) ECIAI39_1705(ldhA)
            EUM: ECUMN_1647(ldhA) ECUMN_2467(dld)
            ECZ: ECS88_1496(ldhA) ECS88_2277(dld)
            ECL: EcolC_1514 EcolC_2275
            EBR: ECB_01352(ldhA) ECB_02063(dld)
            EBD: ECBD_1525 ECBD_2243
            EFE: EFER_1618(ldhA) EFER_2220(dld)
            STY: STY1422(ldhA) STY2397(dld)
            STT: t0688(dld) t1550(ldhA)
            STM: STM1647(ldhA) STM2167(dld)
            SPT: SPA0684(dld) SPA1239(ldhA)
            SEK: SSPA0643 SSPA1148
            SPQ: SPAB_00852 SPAB_01625
            SEI: SPC_1536(dld) SPC_2088(ldhA)
            SEC: SC1642(ldhA) SC2183(dld)
            SEH: SeHA_C1827 SeHA_C2401
            SEE: SNSL254_A1764 SNSL254_A2356
            SEW: SeSA_A1767 SeSA_A2405
            SEA: SeAg_B1509 SeAg_B2312
            SED: SeD_A1692 SeD_A2513
            SEG: SG1472(ldhA) SG2203(dld)
            SET: SEN1405(ldhA) SEN2161(dld)
            SES: SARI_00732 SARI_01337
            YPE: YPO1177(dld) YPO2329(hslI)
            YPK: y2004(ldhA) y3012(dld)
            YPA: YPA_0888 YPA_1678
            YPN: YPN_1788 YPN_2800
            YPM: YP_0960(dld) YP_2115(ldhA1)
            YPP: YPDSF_0817 YPDSF_2519
            YPG: YpAngola_A1351(dld) YpAngola_A2212(ldhA)
            YPZ: YPZ3_1085 YPZ3_1548(ldhA)
            YPS: YPTB1218(dld) YPTB2248(ldhA)
            YPI: YpsIP31758_1808(ldhA) YpsIP31758_2805(dld)
            YPY: YPK_1918 YPK_2884
            YPB: YPTS_1306 YPTS_2324
            YEN: YE2098(hslI) YE2883(dld)
            SFL: SF1814(ldhA) SF2218(dld)
            SFX: S1459(ldhA) S2347(dld)
            SFV: SFV_1805(ldhA) SFV_2209(dld)
            SSN: SSON_1744(ldhA) SSON_2190(dld)
            SBO: SBO_1011(dld) SBO_1686(ldhA)
            SBC: SbBS512_E0839(dld) SbBS512_E1618(idhA)
            SDY: SDY_1464(ldhA) SDY_2155(dld)
            ECA: ECA2000(ldhA) ECA3181(dld)
            PCT: PC1_2294
            PWA: Pecwa_1315 Pecwa_2594
            ETA: ETA_16590(ldhA) ETA_22430(dld)
            EPY: EpC_17290(ldhA) EpC_23750(dld)
            EAM: EAMY_1235(dld) EAMY_1851(ldhA)
            EAY: EAM_1235(dld) EAM_1816(ldhA)
            EBI: EbC_13750(dld) EbC_22810(idhA)
            PLU: plu2145(ldhA) plu2848(dld)
            PAY: PAU_01690(dld) PAU_02421(ldhA)
            ENT: Ent638_1942 Ent638_2732
            ENC: ECL_02165 ECL_03443
            ESC: Entcl_1569 Entcl_2431
            ESA: ESA_01106 ESA_01687
            CTU: Ctu_22700(ldhA) Ctu_28020(dld)
            KPN: KPN_01449(ldhA) KPN_02569(dld)
            KPE: KPK_1598(dld) KPK_3023(ldhA)
            KPU: KP1_2458(ldhA) KP1_3796(dld)
            KVA: Kvar_1495 Kvar_2919
            CKO: CKO_00661 CKO_01429
            CRO: ROD_16401(ldhA) ROD_22521(dld)
            SPE: Spro_1364 Spro_2600
            PMR: PMI0847(dld) PMI1181(ldhA)
            EIC: NT01EI_1147 NT01EI_1938
            ETR: ETAE_1048(dld) ETAE_1771(ldhA)
            HDE: HDEF_1992(ldhA)
            DDA: Dd703_1743
            DDC: Dd586_1740
            DDD: Dda3937_03144(ldhA)
            DZE: Dd1591_1778
            XBO: XBJ1_2373(ldhA) XBJ1_2871(dld)
            XNE: XNC1_2204(ldhA) XNC1_2755(dld)
            PAM: PANA_1245(dld) PANA_2011(ldhA)
            PVA: Pvag_0621(dld) Pvag_1438(ldhA)
            PAO: Pat9b_1192 Pat9b_2025
            RIP: RIEPE_0262
            HIN: HI0085(ldhA) HI1649(dld)
            HIT: NTHI0099(ddh) NTHI1952(dld)
            HIP: CGSHiEE_03810
            HIQ: CGSHiGG_01925 CGSHiGG_02970(cysS)
            HIF: HIBPF00830 HIBPF05920
            HIL: HICON_03580 HICON_14500
            HAP: HAPS_1875(dld) HAPS_2117(ldhA)
            HSO: HS_0784(dld)
            HSM: HSM_1251
            MSU: MS2079(ldhA)
            APL: APL_0687(dld)
            APJ: APJL_0685(dld)
            APA: APP7_0729
            ASU: Asuc_0005
            AAP: NT05HA_1399
            AAT: D11S_1899
            XFA: XF0347
            XFT: PD1708
            XFM: Xfasm12_1878
            XFN: XfasM23_1801
            XCC: XCC0708(dld)
            XCB: XC_3526
            XCA: xccb100_3647(dld)
            XCV: XCV0814
            XAC: XAC0762(dld)
            XOO: XOO3841(dld)
            XOM: XOO_3619
            XOP: PXO_04382
            XAL: XALc_2827(glcD)
            SML: Smlt0738(glcD) Smlt1351(ldhA) Smlt2907(dld)
            SMT: Smal_0587 Smal_1136 Smal_2359
            PSU: Psesu_0627
            VCH: VCA0192
            VCO: VC0395_1085(ldhA)
            VCM: VCM66_A0188(ldhA)
            VCJ: VCD_000057
            VVU: VV1_2200
            VVY: VV2174
            VVM: VVM_02104
            VPA: VPA0144 VPA1005
            VHA: VIBHAR_05675 VIBHAR_06767
            VSP: VS_II0150
            VEX: VEA_000051 VEA_000855
            VFI: VF_1055(ldhA)
            VFM: VFMJ11_1128
            PPR: PBPRA1210 PBPRA2224
            PAE: PA0927(ldhA)
            PAU: PA14_52270(ldhA)
            PAP: PSPA7_4583(ldhA)
            PAG: PLES_43891(ldhA)
            PPU: PP_1649(ldhA)
            PPF: Pput_4068
            PPG: PputGB1_1251
            PPW: PputW619_1211
            PFL: PFL_4452(ldhA)
            PFO: Pfl01_4223
            PFS: PFLU3778
            PEN: PSEEN1358(ldhA)
            PMY: Pmen_1729 Pmen_3636
            PSA: PST_0207(ldhA)
            CJA: CJA_1606
            AVN: Avin_07010
            PRW: PsycPRwf_1080
            ACI: ACIAD0109(dld)
            ACD: AOLE_19020
            ACB: A1S_0070
            ABM: ABSDF0088(dld)
            ABY: ABAYE3796(dld)
            ABC: ACICU_00096
            ABN: AB57_0119
            ABB: ABBFA_003442
            SON: SO_0968(ldhA)
            SDN: Sden_3047
            SFR: Sfri_0518
            SAZ: Sama_0612
            SBL: Sbal_0858
            SBM: Shew185_3506
            SBN: Sbal195_3629
            SBP: Sbal223_3434
            SLO: Shew_0787
            SPC: Sputcn32_0904
            SSE: Ssed_0825
            SPL: Spea_0742
            SHE: Shewmr4_0807
            SHM: Shewmr7_3216
            SHN: Shewana3_3319
            SHW: Sputw3181_3268
            SHL: Shal_0795
            SWD: Swoo_0923
            SWP: swp_4333
            SVO: SVI_3585(ldhA)
            PAT: Patl_2088
            PSM: PSM_A1762
            SDE: Sde_2866
            MAQ: Maqu_3853
            AMC: MADE_01443 MADE_01510 MADE_01901
            PIN: Ping_0091
            TTU: TERTU_1470 TERTU_3161
            FBL: Fbal_1852
            MCA: MCA0182
            TCX: Tcr_1607
            NOC: Noc_0352
            NHL: Nhal_0471
            NWA: Nwat_0800 Nwat_2751
            ALV: Alvin_0120
            TGR: Tgr7_0755
            TKM: TK90_0079 TK90_2214
            HNA: Hneap_0071 Hneap_0673 Hneap_2252
            CSA: Csal_3144
            MMW: Mmwyl1_2752 Mmwyl1_3029
            AHA: AHA_4145
            ASA: ASA_0168(ldhA)
            TAU: Tola_1538
            AFE: Lferr_0313 Lferr_2757
            AFR: AFE_0140 AFE_3161
            NMA: NMA1205(dld) NMA1944
            NME: NMB0997(dld) NMB1685(ldhA)
            NMC: NMC0984(dld) NMC1603(ldhA)
            NMN: NMCC_0940(dld) NMCC_1598(ldhA)
            NMI: NMO_0906(dld) NMO_1504(ldhA)
            NGO: NGO0890 NGO1336
            NGK: NGK_0915 NGK_1561
            NLA: NLA_12360(dld) NLA_5960(ldhA)
            RSO: RSc3131(ldhA)
            RSC: RCFBP_10306(ldhA)
            RSL: RPSI07_0354(ldhA)
            RPI: Rpic_3406
            RPF: Rpic12D_3060
            REU: Reut_B4140
            REH: H16_A1681(ldhA1) H16_A1682(ldhA2)
            CTI: RALTA_A1561(ldhA)
            BMA: BMA2050(ldhA)
            BMV: BMASAVP1_A0863(ldhA)
            BML: BMA10229_A2695(ldhA)
            BMN: BMA10247_1915(ldhA)
            BPS: BPSL2734(ldhA)
            BPM: BURPS1710b_3221
            BPL: BURPS1106A_3207
            BPD: BURPS668_3168
            BPR: GBP346_A3348
            BTE: BTH_I1402
            BVI: Bcep1808_0762 Bcep1808_6274
            BUR: Bcep18194_A3918
            BCN: Bcen_0342
            BCH: Bcen2424_0825
            BCM: Bcenmc03_0795
            BCJ: BCAL2487(dld) BCAL3179(ldhA)
            BAM: Bamb_0705
            BAC: BamMC406_0722
            BMU: Bmul_2558
            BMJ: BMULJ_00680(ldhA)
            BXE: Bxe_A3894 Bxe_B2160
            BPH: Bphy_2429
            BPY: Bphyt_0787 Bphyt_2057
            BGE: BC1002_0555 BC1002_5601
            BPE: BP0651(dld)
            BBR: BB4787(dld)
            AJS: Ajs_2163 Ajs_2682
            DAC: Daci_3347
            HSE: Hsero_2511(ldhA) Hsero_4055(dld)
            NEU: NE0899(ldhA) NE1009
            NET: Neut_1304 Neut_2388
            NMU: Nmul_A0193
            TBD: Tbd_1998
            MFA: Mfla_0399
            MMB: Mmol_0658
            MEH: M301_0677
            NIS: NIS_0056
            NAM: NAMH_0636
            MXA: MXAN_7165(ldhA)
            HOH: Hoch_1800
            MES: Meso_3888
            ATU: Atu3870(ldhA)
            BME: BMEII0185
            BMI: BMEA_B1063
            BMF: BAB2_1073
            BMC: BAbS19_II09980
            BMT: BSUIS_B1109
            BMR: BMI_II1115(dld)
            RPB: RPB_2257
            RPC: RPC_4634
            MEX: Mext_0035 Mext_4349
            MEA: Mex_1p4794(ldhA)
            MDI: METDI5391(ldhA)
            MCH: Mchl_1278 Mchl_4751
            MNO: Mnod_3071
            BID: Bind_3451
            RVA: Rvan_1963
            CAK: Caul_1358
            CSE: Cseg_3088
            PZU: PHZ_p0157(ldhA)
            BSB: Bresu_0723
            RSP: RSP_0407
            RSH: Rsph17029_2061
            RSQ: Rsph17025_2329
            RSK: RSKD131_1738
            RDE: RD1_0074(dld)
            PDE: Pden_2928
            KVU: EIO_0742
            HNE: HNE_1654(dld)
            ZMO: ZMO0256 ZMO1237
            ZMN: Za10_0094 Za10_0962
            SJP: SJA_C1-13620(dld)
            GOX: GOX1253
            APT: APA01_20440
            MGM: Mmc1_3296
            SAU: SA2312(ddh) SA2346
            SAV: SAV2524(ddh) SAV2559
            SAW: SAHV_2508(ddh) SAHV_2543
            SAH: SaurJH1_2599 SaurJH1_2635
            SAJ: SaurJH9_2547 SaurJH9_2581
            SAM: MW2444(ddh) MW2480
            SAS: SAS2410 SAS2445
            SAR: SAR2605(ddh) SAR2640
            SAC: SACOL2535 SACOL2574
            SAX: USA300HOU_2513(ddh) USA300HOU_2554
            SAA: SAUSA300_2463(ddh) SAUSA300_2496
            SAO: SAOUHSC_02830 SAOUHSC_02875
            SAE: NWMN_2422 NWMN_2459
            SAD: SAAV_2589 SAAV_2625
            SAB: SAB2398(ddh) SAB2432c
            SEP: SE2074 SE2121
            SER: SERP2087 SERP2133
            SHA: SH0493 SH0545(ddh)
            SSP: SSP0295
            SCA: Sca_2121(ddh)
            SLG: SLGD_00428 SLGD_00476
            SSD: SPSINT_0522
            MCL: MCCL_0071
            PPM: PPSC2_c5290
            LLC: LACR_C33
            SPY: SPy_1170(ddh)
            SPZ: M5005_Spy_0890(ddh)
            SPH: MGAS10270_Spy1004(ddh)
            SPI: MGAS10750_Spy1039(ddh)
            SPJ: MGAS2096_Spy0963(ddh)
            SPK: MGAS9429_Spy1007(ddh)
            SPB: M28_Spy0863(ddh)
            SOZ: Spy49_0919
            SAG: SAG0695(ldhA)
            SAN: gbs0668
            SAK: SAK_0821(ldhA)
            SDS: SDEG_1003(ddh)
            LPL: lp_2057(ldhD)
            LPJ: JDM1_0728 JDM1_1719(ldhD)
            LPS: LPST_C0684 LPST_C1647(ldhD)
            LJO: LJ0045
            LJF: FI9785_110(ldhD)
            LAC: LBA0055(ldhD)
            LSL: LSL_0308(ldhA) LSL_1887(ldhD)
            LDB: Ldb0101(ldhA) Ldb1010 Ldb2021
            LBU: LBUL_0084 LBUL_0917 LBUL_1868
            LDE: LDBND_0073 LDBND_0723 LDBND_0904 LDBND_1860
            LBR: LVIS_0201 LVIS_1352
            LCA: LSEI_0145 LSEI_2156
            LCB: LCABL_01370(ldhD) LCABL_06520(dld) LCABL_23380(ldhA)
            LCZ: LCAZH_0158 LCAZH_2116
            LGA: LGAS_0043
            LRE: Lreu_0043 Lreu_0683 Lreu_1631 Lreu_1692
            LRF: LAR_0040 LAR_0656 LAR_1523 LAR_1580
            LHE: lhv_0064
            LFE: LAF_0030 LAF_0632 LAF_1102 LAF_1770
            LRH: LGG_00158(ldhD) LGG_02163(ldhA)
            LRL: LC705_00155(ldhD) LC705_02167(ldhA)
            LCR: LCRIS_00051(ldhA)
            LAM: LA2_00300
            PPE: PEPE_0876
            EFA: EF2295
            OOE: OEOE_0413 OEOE_1182 OEOE_1709
            LME: LEUM_0373 LEUM_1756 LEUM_2043
            LCI: LCK_00027(ddh) LCK_00222 LCK_00389(ldhD) LCK_00928
            LKI: LKI_03605 LKI_04640 LKI_05650 LKI_06025
            LGS: LEGAS_0052 LEGAS_0107(ldhD2) LEGAS_0329 LEGAS_1415(ldhD1)
                 LEGAS_1857(dld)
            CAC: CA_C1543 CA_C2691
            CPE: CPE0530(ldhD)
            CPF: CPF_0510
            CPR: CPR_0499(idhA)
            CTC: CTC01840
            CDF: CD0394(ldhA)
            CDC: CD196_0379(ldhA)
            CDL: CDR20291_0365(ldhA)
            CBO: CBO3283(ldhA1) CBO3284(fldH)
            CBA: CLB_3339(ldhA-1) CLB_3340(ldhA-2)
            CBH: CLC_3225(ldhA-1) CLC_3226(ldhA-2)
            CBY: CLM_3716(ldhA) CLM_3717(ldhA)
            CBL: CLK_2699(ldhA) CLK_2700(ldhA)
            CBB: CLD_1239(ldhA) CLD_1240(ldhA)
            CBI: CLJ_B3563(ldhA_1) CLJ_B3564(ldhA_2)
            CBT: CLH_2763
            CBF: CLI_3453(ldhA-1) CLI_3454(ldhA-2)
            CBE: Cbei_1506
            CKL: CKL_2215
            CKR: CKR_1949
            CPY: Cphy_1923
            CLJ: CLJU_c32190
            AFN: Acfer_0976
            EEL: EUBELI_00181
            ELM: ELI_3346 ELI_4443
            MPE: MYPE2650
            MMY: MSC_0034(ldh)
            MAA: MAG_1490(ldhD)
            MAL: MAGa1530(ldhD)
            MCD: MCRO_0586 MCRO_0651
            MFR: MFE_01520(ldhA2) MFE_02270(ldhA1)
            MFM: MfeM64YM_0176(ldhD) MfeM64YM_0279
            MBV: MBOVPG45_0163(ldhA)
            MLC: MSB_A0019(pdxB)
            CGL: NCgl0865(cgl0901)
            CGB: cg1027(dld)
            TPR: Tpau_0524
            SCO: SCO2118(dldh2) SCO3594(dldH)
            SGR: SGR_5384
            AAI: AARI_22340(dld)
            BFA: Bfae_05140
            PFR: PFREUD_16710(dld)
            KFL: Kfla_3619
            FRE: Franean1_7138
            AMD: AMED_8290(vanH)
            STP: Strop_2972
            SAQ: Sare_3196
            CAI: Caci_5794
            SNA: Snas_5355
            CWO: Cwoe_1413
            APV: Apar_1039
            OLS: Olsu_0550
            TPA: TP0037
            TPP: TPASS_0037
            SSM: Spirs_4021
            BHY: BHWA1_00747(ldhA)
            BRM: Bmur_2742
            BTH: BT_1575
            BFR: BF1459
            BFS: BF1389(ldhA)
            BVU: BVU_2499
            BHL: Bache_1835
            PDI: BDI_1057
            PMZ: HMPREF0659_A5803
            CHU: CHU_2980(ldhA)
            DFE: Dfer_1648
            SLI: Slin_3550
            CPI: Cpin_5669
            PHE: Phep_1678
            FJO: Fjoh_1917
            COC: Coch_1563
            ZPR: ZPR_0009 ZPR_3405
            FBC: FB2170_14423
            CAO: Celal_2963 Celal_3023
            FNU: FN0487 FN0511
            LBA: Lebu_0987
            STR: Sterm_3357
            SMF: Smon_0230
            IPO: Ilyop_1686
            CAA: Caka_1349
            RBA: RB8859(ldhA)
            PSL: Psta_1479
            IPA: Isop_2965
            EMI: Emin_1013
            SYN: slr1556(ddh)
            SYC: syc0206_d(ldhA)
            SYF: Synpcc7942_1347
            SYP: SYNPCC7002_G0164(ldhA)
            TEL: tlr0711
            CYT: cce_1601
            CYP: PCC8801_2255
            CYN: Cyan7425_2727
            CYH: Cyan8802_2306
            ANA: alr0058
            NPU: Npun_F2517
            AVA: Ava_2660
            PMA: Pro1755(dld)
            PMJ: P9211_13031
            AMR: AM1_5122
            RRS: RoseRS_4355
            RCA: Rcas_0709
            STI: Sthe_3421
            TRA: Trad_1498
            AAE: aq_1769(dld1) aq_727(ldhA)
            HYA: HY04AAS1_0837
            TAL: Thal_0210
            SUL: SYO3AOP1_0314
            SAF: SULAZ_1655
            PMX: PERMA_0506
            TAM: Theam_0973
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.28
            IUBMB Enzyme Nomenclature: 1.1.1.28
            ExPASy - ENZYME nomenclature database: 1.1.1.28
            BRENDA, the Enzyme Database: 1.1.1.28
            CAS: 9028-36-8
///
ENTRY       EC 1.1.1.29                 Enzyme
NAME        glycerate dehydrogenase;
            D-glycerate dehydrogenase;
            hydroxypyruvate reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-glycerate:NAD+ oxidoreductase
REACTION    (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+ [RN:R01388]
ALL_REAC    R01388;
            (other) R00717
SUBSTRATE   (R)-glycerate [CPD:C00258];
            NAD+ [CPD:C00003]
PRODUCT     hydroxypyruvate [CPD:C00168];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13522707]
  AUTHORS   HOLZER H, HOLLDORF A.
  TITLE     [Isolation of D-glycerate dehydrogenase, some properties of the
            enzyme and its application to the enzymic-optic determination of
            hydroxypyruvate in presence of pyruvate.]
  JOURNAL   Biochem. Z. 329 (1957) 292-312.
REFERENCE   2  [PMID:13163046]
  AUTHORS   STAFFORD HA, MAGALDI A, VENNESLAND B.
  TITLE     The enzymatic reduction of hydroxypyruvic acid to D-glyceric acid in
            higher plants.
  JOURNAL   J. Biol. Chem. 207 (1954) 621-9.
  ORGANISM  Pisum sativum
PATHWAY     ec00260  Glycine, serine and threonine metabolism
            ec00630  Glyoxylate and dicarboxylate metabolism
            ec00680  Methane metabolism
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00018  glycerate dehydrogenase
GENES       SSL: SS1G_11729
            BFU: BC1G_06934
            ANI: AN0701.2
            AFM: AFUA_1G13630 AFUA_6G10090
            ANG: An08g06710
            PCS: Pc21g03190
            ECI: UTI89_C3974
            ECA: ECA2721(hprA)
            PAM: PANA_0570(hprA)
            HIN: HI1556
            HIT: NTHI1577
            HIP: CGSHiEE_05360
            HIQ: CGSHiGG_00175
            HAP: HAPS_0755(ldhA)
            HSO: HS_0945(ldhA)
            HSM: HSM_1420
            PMU: PM0559
            MSU: MS1188(ldhA)
            APL: APL_2039(ldhA)
            APJ: APJL_2090
            APA: APP7_2126
            ASU: Asuc_1432
            AAP: NT05HA_0663
            AAT: D11S_0982
            VCH: VC2504
            VCO: VC0395_A2086
            VVU: VV1_1462
            VVY: VV2923
            VPA: VP2678
            VHA: VIBHAR_03673
            VSP: VS_0352
            VEX: VEA_002395
            PPR: PBPRA0407
            PAE: PA4626(hprA)
            PAU: PA14_61210(hprA)
            PAP: PSPA7_5272(hprA)
            PAG: PLES_50111(hprA)
            PPU: PP_0762(hprA)
            PPF: Pput_0790
            PPG: PputGB1_0804
            PPW: PputW619_4426
            PFL: PFL_5121
            PFO: Pfl01_4711
            PFS: PFLU0920(hprA)
            PEN: PSEEN0907
            PMY: Pmen_3664
            PSA: PST_1117(hprA)
            AVN: Avin_41230
            PAR: Psyc_1987
            PCR: Pcryo_2289
            PRW: PsycPRwf_0110
            ACI: ACIAD1301 ACIAD3278(hprA)
            MCT: MCR_1529
            SON: SO_3631(hprA)
            SDN: Sden_2881
            SFR: Sfri_3072
            SAZ: Sama_2811
            SBL: Sbal_0985
            SBM: Shew185_1054
            SBN: Sbal195_1087
            SBP: Sbal223_3304
            SLO: Shew_0887
            SPC: Sputcn32_0997
            SSE: Ssed_0972
            SPL: Spea_0870
            SHE: Shewmr4_0913
            SHM: Shewmr7_3107
            SHN: Shewana3_3201
            SHW: Sputw3181_3170
            SHL: Shal_0923
            SWD: Swoo_1022
            SWP: swp_4079
            SVO: SVI_0804(hprA)
            ILO: IL1569
            CPS: CPS_4284
            MAQ: Maqu_3054
            AMC: MADE_04030
            FBL: Fbal_3352
            LLO: LLO_1420
            NOC: Noc_2032
            NHL: Nhal_2802
            AEH: Mlg_1400
            HHA: Hhal_0010
            TGR: Tgr7_1201
            HCH: HCH_01519
            CSA: Csal_1842
            HEL: HELO_2556(hprA)
            ABO: ABO_2391(hprA)
            KKO: Kkor_0180
            MMW: Mmwyl1_2206
            AHA: AHA_3230
            ASA: ASA_1084
            DNO: DNO_0848
            GPB: HDN1F_14010
            NMA: NMA0274
            NME: NMB0029(hprA)
            NMC: NMC0006
            NMN: NMCC_0030(hprA)
            NMI: NMO_1977
            NLA: NLA_0030
            CVI: CV_3789
            LHK: LHK_01809
            REH: H16_B0611(hprA)
            BUR: Bcep18194_A4851
            BCN: Bcen_1211
            BCH: Bcen2424_1690
            BCM: Bcenmc03_1662
            BCJ: BCAL1748(hprA)
            BXE: Bxe_B0983
            NEU: NE0101(hprA)
            NET: Neut_2243
            AZO: azo0826
            TMZ: Tmz1t_1148
            CCV: CCV52592_1540
            CHA: CHAB381_0045
            ANT: Arnit_0144
            GSU: GSU1672(hprA)
            GME: Gmet_2695
            GUR: Gura_2789
            GLO: Glov_2385
            GBM: Gbem_1648(hprA)
            GEO: Geob_1052
            GEM: GM21_2565
            PCA: Pcar_2462
            PPD: Ppro_2951
            DVU: DVU1412
            DVL: Dvul_1662
            DVM: DvMF_0209
            DDE: Dde_1681
            DDS: Ddes_0856
            DSA: Desal_2628
            LIP: LI1043(hprA)
            SAT: SYN_00869
            BJA: bll2918
            XAU: Xaut_1534
            MEX: Mext_1796
            MEA: Mex_1p1727(hprA)
            MDI: METDI2479(hprA)
            MET: M446_6553
            MNO: Mnod_7113
            GBE: GbCGDNIH1_0049 GbCGDNIH1_0364
            LLK: LLKF_2278
            LSL: LSL_1099(serA)
            LRL: LC705_02864(hprA)
            OOE: OEOE_0701
            LME: LEUM_0970
            LKI: LKI_03675
            CAC: CA_C2945
            CBE: Cbei_1946
            CCE: Ccel_3425
            CLJ: CLJU_c33430
            CSH: Closa_1790
            CCB: Clocel_0642
            AMT: Amet_2953
            VPR: Vpar_0250
            DSY: DSY0996
            DHD: Dhaf_2079
            HAS: Halsa_2088
            ELE: Elen_2575
            TDE: TDE1616(hprA)
            SSM: Spirs_2574
            BHY: BHWA1_02068
            BRM: Bmur_1725
            SUS: Acid_4712
            BTH: BT_1207
            BFR: BF1882
            BFS: BF1944
            BVU: BVU_3910
            PGI: PG1190(hprA)
            PRU: PRU_0689(hprA)
            PMZ: HMPREF0659_A7303
            DFE: Dfer_4232
            SLI: Slin_4694
            COC: Coch_1961
            IPO: Ilyop_1073
            RBA: RB6394
            TTH: TTC0124
            TTJ: TTHA0500
            SAF: SULAZ_0219
            PMX: PERMA_1233
            MMP: MMP0870
            MMQ: MmarC5_0678
            MMX: MmarC6_1785
            MMZ: MmarC7_0118
            TAC: Ta0858
            TVO: TVN0960
            PTO: PTO1116
            RCI: RCIX739(hprA)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.29
            IUBMB Enzyme Nomenclature: 1.1.1.29
            ExPASy - ENZYME nomenclature database: 1.1.1.29
            BRENDA, the Enzyme Database: 1.1.1.29
            CAS: 9028-37-9
///
ENTRY       EC 1.1.1.30                 Enzyme
NAME        3-hydroxybutyrate dehydrogenase;
            NAD-beta-hydroxybutyrate dehydrogenase;
            hydroxybutyrate oxidoreductase;
            beta-hydroxybutyrate dehydrogenase;
            D-beta-hydroxybutyrate dehydrogenase;
            D-3-hydroxybutyrate dehydrogenase;
            D-(-)-3-hydroxybutyrate dehydrogenase;
            beta-hydroxybutyric acid dehydrogenase;
            3-D-hydroxybutyrate dehydrogenase;
            beta-hydroxybutyric dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-3-hydroxybutanoate:NAD+ oxidoreductase
REACTION    (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH + H+ [RN:R01361]
ALL_REAC    R01361
SUBSTRATE   (R)-3-hydroxybutanoate [CPD:C01089];
            NAD+ [CPD:C00003]
PRODUCT     acetoacetate [CPD:C00164];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also oxidizes other 3-hydroxymonocarboxylic acids.
REFERENCE   1  [PMID:4291491]
  AUTHORS   Bergmeyer HU, Gawehn K, Klotzsch H, Krebs HA, Williamson DH.
  TITLE     Purification and properties of crystalline 3-hydroxybutyrate
            dehydrogenase from Rhodopseudomonas spheroides.
  JOURNAL   Biochem. J. 102 (1967) 423-31.
  ORGANISM  Rhodopseudomonas spheroides
REFERENCE   2  [PMID:4954074]
  AUTHORS   Delafield FP, Cooksey KE, Doudoroff M.
  TITLE     beta-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas
            lemoignei.
  JOURNAL   J. Biol. Chem. 240 (1965) 4023-8.
  ORGANISM  Pseudomonas lemoignei
REFERENCE   3  [PMID:14415394]
  AUTHORS   LEHNINGER AL, SUDDUTH HC, WISE JB.
  TITLE     D-beta-Hydroxybutyric dehydrogenase of muitochondria.
  JOURNAL   J. Biol. Chem. 235 (1960) 2450-5.
  ORGANISM  Rattus norvegicus [GN:rno]
PATHWAY     ec00072  Synthesis and degradation of ketone bodies
            ec00650  Butanoate metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K00019  3-hydroxybutyrate dehydrogenase
GENES       HSA: 56898(BDH2) 622(BDH1)
            PTR: 460970(BDH1) 462895
            PON: 100433252 100445288
            MCC: 709490 711108
            MMU: 69772(Bdh2) 71911(Bdh1)
            RNO: 117099(Bdh1) 295458(Bdh2)
            CFA: 478497(BDH2) 488037(BDH1)
            AML: 100465803 100469005
            BTA: 515321(BDH2) 534090(BDH1)
            SSC: 100155725(BDH1) 100156120 100522692
            ECB: 100068172 100069438
            MDO: 100012027 100032119
            OAA: 100076108 100082234
            GGA: 422715(BDH2) 424891(BDH1)
            TGU: 100220657 100225954
            XLA: 734851(bdh2)
            XTR: 100485678 100495647
            DRE: 100037356(bdh1) 550507(bdh2)
            BFO: BRAFLDRAFT_280425 BRAFLDRAFT_290934 BRAFLDRAFT_290938
            CIN: 100176396 100183445
            SPU: 586067
            DME: Dmel_CG12068 Dmel_CG13377
            DSI: Dsim_GD25863
            ISC: IscW_ISCW021418
            ZMA: 100382931
            AFM: AFUA_5G09290
            DDI: DDB_G0292602
            TET: TTHERM_00039050 TTHERM_01005260
            TBR: Tb10.389.1850
            TCR: 506567.70 507049.60
            ECW: EcE24377A_1665(bdhA)
            ECR: ECIAI1_1486
            ENC: ECL_02406
            KPN: KPN_02057
            KPE: KPK_2273(bdhA)
            KPU: KP1_3134
            KVA: Kvar_2216
            CRO: ROD_15521
            SPE: Spro_0595
            ETR: ETAE_2118
            HSM: HSM_0811
            XCC: XCC2162(hbdH1)
            XCB: XC_1956
            XCA: xccb100_2019
            XCV: XCV2206(bdhA)
            XAC: XAC2045(hbdH1)
            XOO: XOO2218(hbdH1)
            XOM: XOO_2083
            XOP: PXO_00926
            XAL: XALc_1641(bdhA)
            SML: Smlt2084
            SMT: Smal_1682
            PSU: Psesu_1253
            PAE: PA2003(bdhA)
            PAU: PA14_38590(bdhA)
            PAP: PSPA7_3286(bdhA)
            PAG: PLES_33201(bdhA)
            PPU: PP_3073(bdhA)
            PPF: Pput_2651
            PPG: PputGB1_2793
            PPW: PputW619_2718
            PFL: PFL_3576
            PFO: Pfl01_3079
            PFS: PFLU2628
            PEN: PSEEN3158(bdhA)
            PMY: Pmen_4355
            PSA: PST_0861
            AVN: Avin_17590
            PAR: Psyc_1428
            PCR: Pcryo_1592
            PRW: PsycPRwf_1704
            ACI: ACIAD2509(bdhA)
            ACD: AOLE_10030
            ACB: A1S_1737
            ABY: ABAYE1909(bdhA)
            ABC: ACICU_01774
            ABN: AB57_1967
            ABB: ABBFA_001757
            SAZ: Sama_0517
            SHN: Shewana3_3466
            CPS: CPS_0943(bdhA1) CPS_4091(bdhA2)
            PHA: PSHAa2944(bdhA)
            PAT: Patl_1976
            PSM: PSM_A3048(bdhA)
            SDE: Sde_1324
            MAQ: Maqu_0088
            AMC: MADE_02266
            TTU: TERTU_2759
            LPN: lpg2316(bdhA)
            LPF: lpl2236
            LPP: lpp2264
            LPC: LPC_1783(bdhA)
            LPA: lpa_03322(bdhA)
            LLO: LLO_0620
            FTL: FTL_1281
            FPH: Fphi_1807
            CSA: Csal_1825
            HEL: HELO_2542(bdh)
            ABO: ABO_1479
            CVI: CV_0695(bdhA)
            RSO: RS02396(RSp1059) RSc1572
            RSC: RCFBP_11568(bdhA)
            RSL: RPSI07_1661(bdhA) RPSI07_mp1092
            RPI: Rpic_1981 Rpic_4270
            RPF: Rpic12D_1651 Rpic12D_4380
            REU: Reut_A1271 Reut_B3729
            REH: H16_A1334 H16_A1814
            RME: Rmet_0546 Rmet_1156
            CTI: RALTA_A1256
            BMA: BMAA0017(bdhA-1) BMAA0876(bdhA-2)
            BMV: BMASAVP1_1167(bdhA-1)
            BML: BMA10229_0018(bdhA-2) BMA10229_1447(bdhA-1)
            BMN: BMA10247_A0021(bdhA-1) BMA10247_A0918(bdhA-2)
            BPS: BPSS0017 BPSS0354
            BPM: BURPS1710b_A1524(bdhA-1) BURPS1710b_A1918(bdhA-2)
            BPL: BURPS1106A_A0021(bdhA) BURPS1106A_A0505(bdhA)
            BPD: BURPS668_A0023(bdhA) BURPS668_A0602(bdhA)
            BTE: BTH_II0019 BTH_II2038
            BVI: Bcep1808_2297 Bcep1808_3778
            BUR: Bcep18194_A5540 Bcep18194_B3167
            BCN: Bcen_5146 Bcen_5865
            BCH: Bcen2424_2212 Bcen2424_5713
            BCM: Bcenmc03_2236 Bcenmc03_4526
            BCJ: BCAL2304 BCAM0022
            BAM: Bamb_2250 Bamb_4982
            BAC: BamMC406_2129 BamMC406_3125 BamMC406_5564
            BMU: Bmul_1065 Bmul_5312
            BMJ: BMULJ_02193(bdh) BMULJ_03209(bdh)
            BXE: Bxe_A3156 Bxe_B0969
            BPH: Bphy_1961 Bphy_5791
            BPY: Bphyt_1393 Bphyt_2411
            BGL: bglu_2g00220
            BGE: BC1002_1010
            PNU: Pnuc_1386
            PNE: Pnec_0575
            BPE: BP0229 BP2454
            BPA: BPP3441 BPP3638
            BBR: BB3891 BB4073
            BPT: Bpet1600 Bpet1647
            BAV: BAV0263(bdhA) BAV2676(hbdH)
            AXY: AXYL_01235(bdhA1) AXYL_04586(bdhA2) AXYL_06209(bdhA4)
            RFR: Rfer_2069 Rfer_3285
            POL: Bpro_2705
            PNA: Pnap_2539
            AAV: Aave_1586
            AJS: Ajs_3151
            DIA: Dtpsy_2498
            VEI: Veis_4364
            DAC: Daci_1543 Daci_2854
            VAP: Vapar_2220 Vapar_2585
            VPE: Varpa_3338 Varpa_3666
            CTT: CtCNB1_1975
            ADN: Alide_1315
            MPT: Mpe_A1576
            HAR: HEAR1805(bdhA)
            MMS: mma_1483(bdh)
            HSE: Hsero_1246
            LCH: Lcho_1897
            TIN: Tint_0677
            EBA: ebA5833
            HMS: HMU10830(bdhA)
            DAL: Dalk_4766
            DAT: HRM2_27420(fabG6)
            ADE: Adeh_2140
            ACP: A2cp1_1817
            AFW: Anae109_1674
            RCM: A1E_05640 A1E_05645
            RFE: RF_1389 RF_1390
            RAK: A1C_06835
            RRJ: RrIowa_1594
            RBE: RBE_1385
            RBO: A1I_07695
            MLO: mll3632 mlr2400
            MCI: Mesci_1333 Mesci_1461
            MES: Meso_3335
            SME: SM_b21010(bdhA)
            SMD: Smed_4500
            RHI: NGR_b05400(bdhA1) NGR_c23850(bdhA2)
            ATU: Atu2308(bdhA) Atu4131
            ARA: Arad_3311(bdhA)
            AVI: Avi_3319(bdhA)
            RET: RHE_CH03123(bdhA)
            REC: RHECIAT_CH0003282(bdhA)
            RLE: RL3569(bdhA) pRL90175(bdhA)
            RLT: Rleg2_2860
            RLG: Rleg_3132 Rleg_6202
            BME: BMEI0268 BMEII1090
            BMI: BMEA_A1829
            BMF: BAB1_1789
            BMB: BruAb1_1762
            BMC: BAbS19_I16720
            BMS: BR1779
            BMT: BSUIS_B1255
            BCS: BCAN_A1817
            BMR: BMI_I1797
            OAN: Oant_1122
            BJA: blr1488(bdhA) blr7029(bdhA)
            BRA: BRADO1076
            BBT: BBta_6971
            RPA: RPA4206
            RPB: RPB_1408
            RPC: RPC_1997 RPC_2000 RPC_4002
            RPD: RPD_1388
            RPE: RPE_1773
            RPT: Rpal_4687
            RPX: Rpdx1_4423
            NWI: Nwi_2755
            NHA: Nham_3554
            OCA: OCAR_7381
            XAU: Xaut_1887
            AZC: AZC_3211 AZC_4577
            SNO: Snov_2821
            MEX: Mext_4730
            MEA: Mex_1p5182(hbd)
            MDI: METDI5783(hbd)
            MRD: Mrad2831_3482
            MET: M446_4798
            MPO: Mpop_5269
            MCH: Mchl_5197
            MNO: Mnod_4591 Mnod_8088
            BID: Bind_2696 Bind_3009
            MSL: Msil_0811
            HDN: Hden_0803
            RVA: Rvan_0168
            CCR: CC_3384
            CCS: CCNA_03495
            CAK: Caul_4481
            CSE: Cseg_0309
            PZU: PHZ_c0562
            BSB: Bresu_2563
            AEX: Astex_1971 Astex_3427
            SIL: SPO1015 SPO2065(bdh-1)
            SIT: TM1040_1342 TM1040_3270
            RSP: RSP_2857
            RSH: Rsph17029_1436
            RSQ: Rsph17025_1507
            RSK: RSKD131_1100
            RCP: RCAP_rcc01817(bdhA)
            JAN: Jann_2311
            RDE: RD1_2738(bdhA)
            PDE: Pden_0932
            DSH: Dshi_1544
            MMR: Mmar10_0826
            HNE: HNE_0125(bdhA)
            HBA: Hbal_1593
            NAR: Saro_1750
            SAL: Sala_0938
            SWI: Swit_3432
            SJP: SJA_C1-05660(bdh) SJA_C1-24630(bdh)
            ELI: ELI_07105
            ACR: Acry_0494 Acry_2355
            RRU: Rru_A1057
            RCE: RC1_1846(bdhA)
            MAG: amb2677
            AZL: AZL_003180(bdh) AZL_d00150(bdh)
            PBR: PB2503_10594
            APB: SAR116_1330
            BSU: BSU38970(yxjF)
            BSS: BSUW23_19325(yxjF)
            BAN: BA_4249
            BAR: GBAA_4249
            BAT: BAS3941
            BAH: BAMEG_4288
            BAI: BAA_4270
            BAL: BACI_c39970
            BCE: BC4030
            BCA: BCE_4084
            BCZ: BCZK3788
            BCR: BCAH187_A4157
            BCB: BCB4264_A4137
            BCU: BCAH820_4051
            BCG: BCG9842_B1101
            BCQ: BCQ_3820
            BCX: BCA_4141
            BCY: Bcer98_2729
            BTK: BT9727_3773
            BTL: BALH_3648
            BTB: BMB171_C3694
            BWE: BcerKBAB4_3859
            BAY: RBAM_018200(yxjF) RBAM_037840(yxjF1)
            BAO: BAMF_1916(yxjF)
            BAE: BATR1942_17505
            BCL: ABC3434(bdh)
            BMQ: BMQ_2208
            BMD: BMD_2166
            OIH: OB2631
            GKA: GK1983
            GTN: GTNG_1881
            GYC: GYMC61_2816
            GYA: GYMC52_1946
            GCT: GC56T3_1530
            SSP: SSP2198
            LSP: Bsph_1310
            ESI: Exig_1174
            EAT: EAT1b_0231
            BBE: BBR47_03510(yxjF)
            AAC: Aaci_0240
            SPY: SPy_1640
            SPZ: M5005_Spy_1347
            SPM: spyM18_1649
            SPG: SpyM3_1381 SpyM3_1382
            SPS: SPs0480 SPs0481
            SPH: MGAS10270_Spy1464
            SPI: MGAS10750_Spy1456
            SPJ: MGAS2096_Spy1368
            SPK: MGAS9429_Spy1342
            SPF: SpyM50444
            SPA: M6_Spy1393
            SPB: M28_Spy1388
            SOZ: Spy49_1271
            SEQ: SZO_05220
            SEZ: Sez_1434
            SEU: SEQ_1624
            SUB: SUB1397
            SDS: SDEG_1703
            CDF: CD2679(bdhA)
            CDC: CD196_2520(bdhA)
            CDL: CDR20291_2567(bdhA)
            MSM: MSMEG_6026
            MVA: Mvan_5299
            MGI: Mflv_1472
            MMC: Mmcs_4701
            MKM: Mkms_4787
            MJL: Mjls_5086
            MSP: Mspyr1_46950
            CGT: cgR_2407
            CEF: CE2393
            NFA: nfa28660
            RHA: RHA1_ro04778
            RER: RER_20930(bdhA)
            ROP: ROP_48680(bdhA)
            TPR: Tpau_0773
            SCO: SCO1012(2SCG2.25c)
            SMA: SAV_1420(bdhA)
            SGR: SGR_1195
            ART: Arth_0366
            AAU: AAur_0392(bdh)
            ACH: Achl_0578
            AAI: AARI_28270(bdhA)
            RSA: RSal33209_3111
            KRH: KRH_02330(bdh)
            KSE: Ksed_10310
            ICA: Intca_1917
            KFL: Kfla_5322
            TFU: Tfu_0081
            NDA: Ndas_0047
            SRO: Sros_8513
            NML: Namu_3917
            GOB: Gobs_4841
            SEN: SACE_3718 SACE_6685
            SVI: Svir_10030
            AMD: AMED_5954(bdh)
            STP: Strop_1807
            SAQ: Sare_1797
            MAU: Micau_2287
            MIL: ML5_2399
            CAI: Caci_7916
            SNA: Snas_5331
            RXY: Rxyl_2343
            CWO: Cwoe_0126
            CYC: PCC7424_0442
            CYJ: Cyan7822_4863
            CAU: Caur_2956
            CAG: Cagg_3770
            CHL: Chy400_3201
            DGE: Dgeo_0952
            DDR: Deide_14910
            DMR: Deima_2547
            TRA: Trad_2000
            TTH: TTC0333
            TTJ: TTHA0693
            TSC: TSC_c09010
            MRB: Mrub_1680
            MSV: Mesil_2335
            OPR: Ocepr_2085
            CNI: Calni_1356
            HMA: rrnAC0648(bdhA)
            NPH: NP6040A
            HUT: Huta_0855
            HTU: Htur_1329
            NMG: Nmag_2584
            HJE: HacjB3_04110
            HBO: Hbor_25950 Hbor_32220
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.30
            IUBMB Enzyme Nomenclature: 1.1.1.30
            ExPASy - ENZYME nomenclature database: 1.1.1.30
            BRENDA, the Enzyme Database: 1.1.1.30
            CAS: 9028-38-0
///
ENTRY       EC 1.1.1.31                 Enzyme
NAME        3-hydroxyisobutyrate dehydrogenase;
            beta-hydroxyisobutyrate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase
REACTION    3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate +
            NADH + H+ [RN:R02047]
ALL_REAC    R02047 > R05066
SUBSTRATE   3-hydroxy-2-methylpropanoate [CPD:C01188];
            NAD+ [CPD:C00003]
PRODUCT     2-methyl-3-oxopropanoate [CPD:C00349];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13416257]
  AUTHORS   ROBINSON WG, COON MJ.
  TITLE     The purification and properties of beta-hydroxyisobutyric
            dehydrogenase.
  JOURNAL   J. Biol. Chem. 225 (1957) 511-21.
  ORGANISM  Sus scofa [GN:ssc]
PATHWAY     ec00280  Valine, leucine and isoleucine degradation
            ec01100  Metabolic pathways
ORTHOLOGY   K00020  3-hydroxyisobutyrate dehydrogenase
GENES       HSA: 11112(HIBADH)
            PTR: 463313(HIBADH)
            PON: 100174700(HIBADH)
            MCC: 702794(HIBADH) 706933(N-PAC)
            MMU: 58875(Hibadh)
            RNO: 63938(Hibadh)
            CFA: 479610(HIBADH)
            AML: 100468892
            BTA: 512002(HIBADH)
            SSC: 100516656
            ECB: 100054707(HIBADH)
            MDO: 100010435 100019201(GLYR1)
            OAA: 100080437
            GGA: 420632(HIBADH)
            TGU: 100229283
            XLA: 431794(hibadh) 495134
            XTR: 594992(hibadh)
            DRE: 394135(hibadhb)
            BFO: BRAFLDRAFT_270300
            CIN: 100178943
            DME: Dmel_CG15093 Dmel_CG4747
            DPO: Dpse_GA13484 Dpse_GA18401
            DAN: Dana_GF13754
            DER: Dere_GG20945
            DPE: Dper_GL11305
            DSE: Dsec_GM19876
            DSI: Dsim_GD25359
            DYA: Dyak_GE13884
            DGR: Dgri_GH19800
            DMO: Dmoj_GI20341
            DVI: Dvir_GJ22064
            AGA: AgaP_AGAP005581
            AAG: AaeL_AAEL006684 AaeL_AAEL013904
            CQU: CpipJ_CPIJ000400 CpipJ_CPIJ015209
            AME: 551208
            PHU: Phum_PHUM035240
            CEL: B0250.5
            CBR: CBG05595
            NVE: NEMVE_v1g178116 NEMVE_v1g238019
            HMG: 100212438
            TAD: TRIADDRAFT_50898
            ATH: AT4G20930
            POP: POPTR_550610
            RCU: RCOM_1337110
            VVI: 100242424
            OSA: 9268115
            ZMA: 100283587
            PPP: PHYPADRAFT_205200
            OLU: OSTLU_45774
            DHA: DEHA2A06116g
            PIC: PICST_35865(HIB1)
            PGU: PGUG_03513
            LEL: LELG_04908
            CAL: CaO19.13011 CaO19.5565
            CTP: CTRG_05388
            CDU: CD36_63190
            YLI: YALI0F02607g
            CLU: CLUG_05312
            NCR: NCU06559 NCU10110
            PAN: PODANSg171
            MGR: MGG_01687(MG01687.4) MGG_03097(MG03097.4)
            FGR: FG05284.1
            SSL: SS1G_08367 SS1G_12199
            BFU: BC1G_01790 BC1G_08732
            ANI: AN0593.2 AN2335.2
            AFM: AFUA_3G09470 AFUA_5G01250 AFUA_5G10280 AFUA_6G11020
            NFI: NFIA_056750 NFIA_076980
            AOR: AO090010000515 AO090023000518
            ANG: An08g07890 An14g04420
            AFV: AFLA_109320 AFLA_119960
            ACT: ACLA_013350 ACLA_084700
            PCS: Pc21g20910 Pc21g22380 Pc22g13160
            CIM: CIMG_00035 CIMG_02428
            CPW: CPC735_040550 CPC735_060780
            URE: UREG_00163 UREG_03280
            PNO: SNOG_00771 SNOG_05709 SNOG_08720
            TML: GSTUM_00004370001
            LBC: LACBIDRAFT_316080
            CCI: CC1G_05163
            SCM: SCHCODRAFT_65610
            UMA: UM02189.1
            DDI: DDB_G0292566(hibA)
            TGO: TGME49_072410
            TET: TTHERM_01123840
            PTM: GSPATT00035541001
            PTI: PHATRDRAFT_45141
            TPS: THAPSDRAFT_2669 THAPSDRAFT_413
            PIF: PITG_00912
            ECI: UTI89_C5030(ghbD)
            ECV: APECO1_2097(ghbD)
            YPM: YP_3899(mmsB)
            YPP: YPDSF_0255
            EBI: EbC_20420
            KPN: KPN_01687
            KPE: KPK_2679
            KPU: KP1_2739
            KVA: Kvar_2635
            XBO: XBJ1_2393
            PVA: Pvag_1277
            PMU: PM1366
            APL: APL_1197
            APJ: APJL_1213
            APA: APP7_1251
            ASU: Asuc_0552
            XCC: XCC1264(mmsB)
            XCB: XC_2977
            XCA: xccb100_3039
            XCV: XCV1367
            XAC: XAC1316(mmsB)
            XOO: XOO1846(mmsB)
            XOM: XOO_1742
            XOP: PXO_01707(mmsB)
            SML: Smlt0268(mmsB)
            SMT: Smal_0223
            VCH: VCA0007
            VCO: VC0395_0123(garR)
            VVU: VV2_0489 VV2_1637
            VVY: VVA0448 VVA1038
            VPA: VPA0625 VPA1118 VPA1419
            VHA: VIBHAR_05191 VIBHAR_05487
            VEX: VEA_000370 VEA_001550
            VFI: VF_A0173
            PPR: PBPRB1107
            PAE: PA0743 PA1576 PA3312 PA3569(mmsB)
            PAU: PA14_18140(mmsB) PA14_21180 PA14_54670
            PAP: PSPA7_1575(mmsB2) PSPA7_1807 PSPA7_4777(mmsB1)
            PAG: PLES_14641(mmsB) PLES_17531 PLES_46001
            PPU: PP_1143 PP_4666(mmsB)
            PPF: Pput_1177 Pput_4530
            PPG: PputGB1_4274 PputGB1_4664
            PPW: PputW619_0768 PputW619_1160
            PST: PSPTO_0783(mmsB) PSPTO_1880 PSPTO_5060
            PSB: Psyr_0466 Psyr_0690 Psyr_3525
            PSP: PSPPH_0457 PSPPH_3467
            PFL: PFL_0748(mmsB) PFL_1303 PFL_2928 PFL_3346
            PFO: Pfl01_0696 Pfl01_1251
            PFS: PFLU2352 PFLU5202
            PEN: PSEEN0700(mmsB) PSEEN1291
            PMY: Pmen_1371 Pmen_3196
            PSA: PST_1924(mmsB) PST_2974
            AVN: Avin_10700
            PAR: Psyc_0904(mmsB)
            PCR: Pcryo_1513
            PRW: PsycPRwf_0297
            ACI: ACIAD0032 ACIAD1605(mmsB) ACIAD2316 ACIAD3074
            ACD: AOLE_18815
            ACB: A1S_0103
            ABM: ABSDF0122(mmsB)
            ABY: ABAYE3767(mmsB)
            ABC: ACICU_00130
            ABN: AB57_0145(mmsB)
            ABB: ABBFA_003415(mmsB)
            SON: SO_1682(mmsB)
            SDN: Sden_1938
            SFR: Sfri_1343
            SAZ: Sama_1380
            SBL: Sbal_1500
            SBM: Shew185_1494
            SBN: Sbal195_1530
            SBP: Sbal223_2851
            SLO: Shew_1672
            SPC: Sputcn32_1402
            SSE: Ssed_1478 Ssed_2619
            SPL: Spea_2778
            SHE: Shewmr4_2592
            SHM: Shewmr7_2659
            SHN: Shewana3_2554 Shewana3_2766
            SHW: Sputw3181_2699
            SHL: Shal_2873
            SWD: Swoo_3197
            SWP: swp_3382
            SVO: SVI_3098(mmsB)
            ILO: IL0867(mmsB) IL1375
            CPS: CPS_2007 CPS_3424(mmsB)
            PHA: PSHAa1459 PSHAa1750
            PAT: Patl_0951 Patl_2175
            MAQ: Maqu_1147 Maqu_2129
            AMC: MADE_01512
            FBL: Fbal_1023
            CBU: CBU_0926(mmsB)
            CBS: COXBURSA331_A1018(mmsB)
            CBD: CBUD_1148(mmsB)
            CBG: CbuG_1079(mmsB)
            LPN: lpg0128
            LPF: lpl0127
            LPP: lpp0142
            LPC: LPC_0148
            LPA: lpa_00189
            LLO: LLO_3272
            FTU: FTT_1666c
            FTF: FTF1666c
            FTL: FTL_0026 FTL_0027
            FTM: FTM_0006
            NOC: Noc_2077
            NHL: Nhal_1873
            HCH: HCH_00638(mmsB) HCH_04751
            CSA: Csal_1707 Csal_3178
            HEL: HELO_2317 HELO_2425(mmsB)
            ABO: ABO_0022(mmsB) ABO_1503(mmsB)
            MMW: Mmwyl1_0115 Mmwyl1_2547
            AHA: AHA_2083(mmsB)
            ASA: ASA_1917(mmsB)
            GPB: HDN1F_22580(mmsB)
            NMA: NMA1773
            NME: NMB1584
            NMC: NMC1504
            NMN: NMCC_1488
            NMI: NMO_1412
            NGO: NGO1243
            NGK: NGK_0264
            NLA: NLA_6990
            CVI: CV_2081(mmsB) CV_3944
            LHK: LHK_00220 LHK_00757
            RSO: RSp0649(mmsB)
            RSL: RPSI07_mp0526(mmsB)
            RPI: Rpic_3732 Rpic_3976
            RPF: Rpic12D_3409 Rpic12D_4089
            REU: Reut_A1427 Reut_B3944 Reut_B4259 Reut_B5532 Reut_C5900
                 Reut_C5958
            REH: H16_A1239 H16_A1562 H16_A3004 H16_B1190 H16_B1657 H16_B1750
            RME: Rmet_1835 Rmet_2821 Rmet_4459
            CTI: RALTA_A1488 RALTA_B1108(mmsB)
            BMA: BMAA2000
            BMV: BMASAVP1_1021
            BML: BMA10229_1309
            BMN: BMA10247_A2287
            BPS: BPSS0620(mmsB) BPSS2264
            BPM: BURPS1710b_0030 BURPS1710b_A0438 BURPS1710b_A1397
                 BURPS1710b_A2181(mmsB)
            BPL: BURPS1106A_3862 BURPS1106A_A0829(mmsB) BURPS1106A_A3051
            BPD: BURPS668_A0921(mmsB) BURPS668_A3180
            BTE: BTH_II1800(mmsB) BTH_II2294
            BVI: Bcep1808_3334 Bcep1808_4620
            BUR: Bcep18194_A3406 Bcep18194_A5291 Bcep18194_B0478 Bcep18194_B0717
                 Bcep18194_B1214 Bcep18194_B2034 Bcep18194_B2531 Bcep18194_C7141
            BCN: Bcen_3212 Bcen_3407 Bcen_3712 Bcen_4320 Bcen_6098
            BCH: Bcen2424_1979 Bcen2424_4046 Bcen2424_4656 Bcen2424_4960
                 Bcen2424_5155
            BCM: Bcenmc03_2003 Bcenmc03_3479 Bcenmc03_5124 Bcenmc03_5326
                 Bcenmc03_5648
            BCJ: BCAL2056 BCAM1150(mmsB) BCAM2193(mmsB) BCAM2395
            BAM: Bamb_0226 Bamb_3441 Bamb_4382 Bamb_4550
            BAC: BamMC406_3948 BamMC406_4901 BamMC406_5073
            BMU: Bmul_3500 Bmul_3659 Bmul_4543 Bmul_4985
            BMJ: BMULJ_03967(mmsB) BMULJ_04858(mmsB) BMULJ_05017(mmsB)
            BXE: Bxe_A1115 Bxe_A3575 Bxe_B0073 Bxe_B0704 Bxe_B1087 Bxe_B2130
                 Bxe_B2172 Bxe_C0245
            BPH: Bphy_4423 Bphy_4931 Bphy_5129 Bphy_5795
            BPY: Bphyt_5647 Bphyt_5931
            BGL: bglu_2g02820 bglu_2g04900 bglu_2g06290
            BGE: BC1002_3478 BC1002_4207
            PNU: Pnuc_1557 Pnuc_1634
            BPE: BP1169 BP1447(mmsB) BP3053
            BPA: BPP1554(mmsB) BPP1597 BPP3779
            BBR: BB0653 BB0974 BB1031 BB2632(mmsB) BB4224
            BPT: Bpet1194 Bpet2509(mmsB)
            BAV: BAV1760(mmsB)
            AXY: AXYL_02832(mmsB1) AXYL_05994 AXYL_06711
            RFR: Rfer_0446 Rfer_3876
            POL: Bpro_2471 Bpro_4883
            AAV: Aave_0633 Aave_2600
            AJS: Ajs_0417 Ajs_2005
            DIA: Dtpsy_0409 Dtpsy_1809
            VEI: Veis_1431 Veis_1692 Veis_2971 Veis_3388 Veis_3539
            DAC: Daci_1065 Daci_2567 Daci_2811 Daci_3690
            VAP: Vapar_3253 Vapar_5146
            CTT: CtCNB1_2789 CtCNB1_3086
            MPT: Mpe_A3763 Mpe_B0561
            HSE: Hsero_0959(mmsB) Hsero_3066(mmsB) Hsero_4234
            LCH: Lcho_1636
            AZO: azo2540(mmsB)
            HPJ: jhp0585
            HPA: HPAG1_0625
            HPG: HPG27_603
            HPP: HPP12_0654
            HPB: HELPY_0730
            GSU: GSU1372 GSU1451
            GME: Gmet_1972
            GLO: Glov_1328
            DAT: HRM2_44930(ywkC)
            HOH: Hoch_1498 Hoch_3369
            SFU: Sfum_2944
            PUB: SAR11_0863 SAR11_1196(mmsB)
            MLO: mlr0552 mlr1203 mlr2606
            MES: Meso_1308 Meso_1565
            PLA: Plav_2894 Plav_2900
            SME: SM_b20668 SM_b20751 SMc00133
            SMD: Smed_1595 Smed_4243 Smed_4321
            RHI: NGR_b20330 NGR_b20850
            ATU: Atu4129(mmsB)
            ARA: Arad_0837(mmsB) Arad_9439
            RET: RHE_CH02433(ypch00812) RHE_PE00281(ype00138)
                 RHE_PF00345(ypf00176)
            REC: RHECIAT_PA0000227 RHECIAT_PC0000550
            RLE: pRL110152 pRL110406 pRL120616
            RLT: Rleg2_5308 Rleg2_5817
            RLG: Rleg_5012 Rleg_6723
            BME: BMEI0688 BMEI1024
            BMI: BMEA_A0989 BMEA_A1362(mmsB)
            BMF: BAB1_1334
            BMB: BruAb1_1315(mmsB)
            BMC: BAbS19_I12460
            BMS: BR0950 BR1314(mmsB)
            BMT: BSUIS_A0990 BSUIS_A1365(mmsB)
            BOV: BOV_0943 BOV_1276(mmsB)
            BCS: BCAN_A0962 BCAN_A1339(mmsB)
            BMR: BMI_I1327(mmsB) BMI_I948
            OAN: Oant_1870 Oant_2239
            BJA: bll3740 bll6323 blr3957
            BRA: BRADO2551 BRADO3016 BRADO3140 BRADO4737 BRADO5847 BRADO6607
            BBT: BBta_0929 BBta_1985 BBta_2897 BBta_3463 BBta_3581 BBta_5125
            RPA: RPA1973 RPA3446
            RPB: RPB_2122 RPB_3005 RPB_3394
            RPC: RPC_2065 RPC_3091
            RPD: RPD_1854 RPD_2047 RPD_3299
            RPE: RPE_1979 RPE_2387
            RPT: Rpal_2186 Rpal_3935
            NWI: Nwi_1213 Nwi_2156
            NHA: Nham_1470 Nham_2556
            OCA: OCAR_6482(mmsB)
            XAU: Xaut_1027 Xaut_1538 Xaut_2189 Xaut_3451
            AZC: AZC_0577 AZC_2777 AZC_2905
            MRD: Mrad2831_1134 Mrad2831_3004 Mrad2831_3782
            MET: M446_2479 M446_2626
            MNO: Mnod_2177 Mnod_4384 Mnod_4652 Mnod_5498
            BID: Bind_0615 Bind_1788 Bind_2085
            HDN: Hden_1858
            RVA: Rvan_0900 Rvan_3414
            CCR: CC_1354 CC_1574
            CCS: CCNA_01416
            CAK: Caul_3050
            CSE: Cseg_1654
            PZU: PHZ_c1678 PHZ_c1686
            BSB: Bresu_1872 Bresu_1879
            SIL: SPO0792 SPO2213(mmsB-1) SPO2859 SPO3097(mmsB-2)
            SIT: TM1040_0514 TM1040_1101 TM1040_1353
            RSP: RSP_0154 RSP_2846 RSP_3171
            RSH: Rsph17029_1447 Rsph17029_1787 Rsph17029_3909
            RSQ: Rsph17025_1337 Rsph17025_1496
            RSK: RSKD131_1114
            JAN: Jann_1907 Jann_3485
            RDE: RD1_2540(garR) RD1_2751 RD1_2991(mmsB) RD1_3786(mmsB)
            PDE: Pden_3216 Pden_3256 Pden_4003 Pden_4482
            DSH: Dshi_1752(mmsB) Dshi_3047(glxR)
            MMR: Mmar10_1542 Mmar10_1552
            HNE: HNE_0895 HNE_1826(mmsB)
            HBA: Hbal_2700
            NAR: Saro_0861 Saro_1098
            SAL: Sala_3056
            SWI: Swit_0647
            SJP: SJA_C1-15190(mmsB) SJA_C1-20720(mmsB)
            ELI: ELI_10045
            ACR: Acry_0625 Acry_2431 Acry_2697 Acry_3405 Acry_3409
            RRU: Rru_A1833
            RCE: RC1_1347(mmsB)
            MAG: amb3587
            AZL: AZL_a04610 AZL_d04810(mmsB)
            APB: SAR116_1425 SAR116_1436
            MGM: Mmc1_3551
            BSU: BSU07990(yfjR)
            BHA: BH2634
            BAN: BA_2353(garR)
            BAR: GBAA_2353(garR)
            BAT: BAS2192 BAS3952 BAS3953
            BCE: BC2289 BC4042
            BCZ: BCZK2115(garR) BCZK3799
            BCU: BCAH820_4063
            BTK: BT9727_2129(garR) BT9727_3784
            BTL: BALH_2097 BALH_3659
            BWE: BcerKBAB4_2160
            BLI: BL00292 BL03574(ykwC)
            BLD: BLi01606(ykwC)
            BAY: RBAM_013720(ykwC)
            BCL: ABC1808 ABC2403 ABC3811
            BPU: BPUM_1286(ykwC)
            OIH: OB0581 OB0815
            GKA: GK1027
            GTN: GTNG_0889
            GYM: GYMC10_5210
            GCT: GC56T3_2545
            AFL: Aflv_1934
            LMO: lmo1005
            LMF: LMOf2365_1026
            LIN: lin1004
            LWE: lwe0989
            ESI: Exig_1153 Exig_2666
            MCL: MCCL_0178(mmsB)
            PJD: Pjdr2_1256
            BTS: Btus_0939
            LLA: L81616(ywjF)
            LLM: llmg_2494(ywjF)
            LPL: lp_2548(hibD)
            LSA: LSA0463
            LSL: LSL_0010(mmsB)
            LBR: LVIS_1796
            LCA: LSEI_0245
            EFA: EF2889(glxR)
            LME: LEUM_2069
            LCI: LCK_00028
            CAC: CA_C3342
            CPE: CPE0393
            STH: STH938
            DSY: DSY4048
            NTH: Nther_2161
            MPE: MYPE3160
            ACL: ACL_0082(mmsB)
            MTU: Rv0751c(mmsB)
            MTC: MT0775(mmsB) MT0794
            MRA: MRA_0760(mmsB)
            MTF: TBFG_10765
            MTB: TBMG_00765(TBMG_00765.1)
            MBO: Mb0773c(mmsB) Mb0793
            MBB: BCG_0802c(mmsB)
            MBT: JTY_0772(mmsB)
            MPA: MAP0604 MAP4213c(mmsB)
            MAV: MAV_4419(mmsB)
            MSM: MSMEG_1496(mmsB)
            MUL: MUL_0835(mmsB)
            MVA: Mvan_1360 Mvan_4822
            MGI: Mflv_5012
            MAB: MAB_1186c MAB_4486
            MMC: Mmcs_1062
            MKM: Mkms_1078
            MJL: Mjls_1089
            MMI: MMAR_1077(mmsB)
            CAR: cauri_0879(mmsB)
            NFA: nfa10400 nfa46610
            RHA: RHA1_ro01539(mmsB1) RHA1_ro05332(mmsB2) RHA1_ro07079(mmsB3)
                 RHA1_ro08845
            RER: RER_39520(mmsB)
            ROP: ROP_12420(mmsB) ROP_45040(mmsB)
            GBR: Gbro_3849 Gbro_3900
            TPR: Tpau_3068
            SRT: Srot_0672
            SCO: SCO0907(SCM1.40c)
            SMA: SAV_1542
            SGR: SGR_1218
            SCB: SCAB_47481
            CMI: CMM_0268 CMM_0480
            CMS: CMS_0232
            ART: Arth_0422 Arth_1322 Arth_3591
            AAU: AAur_0255 AAur_0501(mmsB) AAur_0651(mmsB)
            ACH: Achl_0632
            RSA: RSal33209_1840(igiB.1) RSal33209_1849 RSal33209_2972
            KRH: KRH_02400(mmsB) KRH_16530(mmsB)
            MLU: Mlut_01370 Mlut_02850
            KSE: Ksed_22120
            NCA: Noca_2159
            NDA: Ndas_2509
            FRA: Francci3_0803
            FRE: Franean1_4518 Franean1_5896
            FRI: FraEuI1c_5400
            FAL: FRAAL2958 FRAAL6073(mmsB)
            SEN: SACE_1371 SACE_1459(mmsB) SACE_3558
            AMD: AMED_3839(mmsB) AMED_6207(mmsB) AMED_6573(mmsB)
            SAQ: Sare_2204
            RXY: Rxyl_0425
            APV: Apar_0981
            OLS: Olsu_1431
            TDE: TDE1000
            LIL: LA_2054(mmsB)
            LIC: LIC11860(mmsB)
            SUS: Acid_7137
            GAU: GAU_2702(mmsB) GAU_3188
            RBA: RB13140(mmsB) RB3816
            ACO: Amico_0028
            SYN: slr0229(mmsB)
            SYW: SYNW2430
            SYC: syc2237_d(mmsB)
            SYF: Synpcc7942_1857
            SYD: Syncc9605_2461 Syncc9605_2601
            SYE: Syncc9902_2237
            SYG: sync_2712
            SYR: SynRCC307_0898
            SYX: SynWH7803_0822
            SYP: SYNPCC7002_A1558(mmsB) SYNPCC7002_A2814
            MAR: MAE_06400 MAE_39960
            CYT: cce_0405(mmsB)
            CYP: PCC8801_1305
            CYJ: Cyan7822_3289
            GVI: glr3759
            ANA: alr3358
            NAZ: Aazo_3884
            PMA: Pro1229(mmsB)
            PMT: PMT2105
            PMN: PMN2A_0231
            PMF: P9303_27951(mmsB)
            PMJ: P9211_11961
            PME: NATL1_08981(mmsB)
            AMR: AM1_4940
            RRS: RoseRS_3990
            RCA: Rcas_2700 Rcas_3343
            HAU: Haur_1907
            DRA: DR_0499
            DDR: Deide_10300
            TTH: TTC1749
            TTJ: TTHA0237
            MRB: Mrub_1312
            MSV: Mesil_0836
            OPR: Ocepr_1773
            AAE: aq_038(hibD)
            HYA: HY04AAS1_1335
            HTH: HTH_0468
            TAL: Thal_1084
            PMX: PERMA_1078
            TYE: THEYE_A0982
            TTR: Tter_1979
            DDF: DEFDS_0651
            CNI: Calni_0288
            MAC: MA0614
            MBN: Mboo_1645
            TAC: Ta0161
            TVO: TVN0231
            PFU: PF0716
            TBA: TERMP_01423
            RCI: RRC500(hibD)
            APE: APE_0756.1
            SMR: Smar_0243
            IAG: Igag_0515
            SSO: SSO0974 SSO1560
            STO: ST0619
            SAI: Saci_0385
            SIS: LS215_0462 LS215_1337
            SIA: M1425_0448 M1425_1250
            SIM: M1627_0461 M1627_1300
            SID: M164_0486 M164_1234
            SIY: YG5714_0423 YG5714_1235
            SIN: YN1551_1613 YN1551_2593
            SII: LD85_0458 LD85_1361
            MSE: Msed_1759
            PAI: PAE1145
            PIS: Pisl_1265
            PCL: Pcal_0699
            PAS: Pars_0236
            CMA: Cmaq_0209 Cmaq_1097
            TNE: Tneu_0210
            VDI: Vdis_0068 Vdis_0379
            TPE: Tpen_0076
            ASC: ASAC_1039
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.31
            IUBMB Enzyme Nomenclature: 1.1.1.31
            ExPASy - ENZYME nomenclature database: 1.1.1.31
            BRENDA, the Enzyme Database: 1.1.1.31
            CAS: 9028-39-1
///
ENTRY       EC 1.1.1.32                 Enzyme
NAME        mevaldate reductase;
            mevalonic dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-mevalonate:NAD+ oxidoreductase
REACTION    (R)-mevalonate + NAD+ = mevaldate + NADH + H+ [RN:R02246]
ALL_REAC    R02246
SUBSTRATE   (R)-mevalonate [CPD:C00418];
            NAD+ [CPD:C00003]
PRODUCT     mevaldate [CPD:C00772];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13747804]
  AUTHORS   SCHLESINGER MJ, COON MJ.
  TITLE     Reduction of mevaldic acid to mevalonic acid by a partially purified
            enzyme from liver.
  JOURNAL   J. Biol. Chem. 236 (1961) 2421-4.
  ORGANISM  Sus scofa [GN:ssc]
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.32
            IUBMB Enzyme Nomenclature: 1.1.1.32
            ExPASy - ENZYME nomenclature database: 1.1.1.32
            BRENDA, the Enzyme Database: 1.1.1.32
            CAS: 9028-33-5
///
ENTRY       EC 1.1.1.33                 Enzyme
NAME        mevaldate reductase (NADPH);
            mevaldate (reduced nicotinamide adenine dinucleotide phosphate)
            reductase;
            mevaldate reductase (NADPH)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-mevalonate:NADP+ oxidoreductase
REACTION    (R)-mevalonate + NADP+ = mevaldate + NADPH + H+ [RN:R02247]
ALL_REAC    R02247
SUBSTRATE   (R)-mevalonate [CPD:C00418];
            NADP+ [CPD:C00006]
PRODUCT     mevaldate [CPD:C00772];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     May be identical with EC 1.1.1.2 [alcohol dehydrogenase (NADP+)].
REFERENCE   1
  AUTHORS   Coon, M.J., Kupiecki, F.P., Dekker, E.E., Schlesinger, M.J. and del
            Campillo, A.
  TITLE     The enzymic synthesis of branched-chain acids.
  JOURNAL   In: Wolstenholme, G.E.W. and O'Connor, M. (Eds.), CIBA Symposium on
            the Biosynthesis of Terpenes and Sterols, CIBA Symposium on the
            Biosynthesis of Terpenes and Sterols, London, 1959, p. 62-74.
REFERENCE   2
  AUTHORS   von Wartburg, J.P. and Wermoth, B.
  TITLE     Aldehyde reductase.
  JOURNAL   In: Jakoby, W.B. (Ed.), Enzymatic Basis of Detoxication, vol. 1,
            Academic Press, New York, 1980, p. 249-260.
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.33
            IUBMB Enzyme Nomenclature: 1.1.1.33
            ExPASy - ENZYME nomenclature database: 1.1.1.33
            BRENDA, the Enzyme Database: 1.1.1.33
            CAS: 9028-34-6
///
ENTRY       EC 1.1.1.34                 Enzyme
NAME        hydroxymethylglutaryl-CoA reductase (NADPH);
            hydroxymethylglutaryl coenzyme A reductase (reduced nicotinamide
            adenine dinucleotide phosphate);
            3-hydroxy-3-methylglutaryl-CoA reductase;
            beta-hydroxy-beta-methylglutaryl coenzyme A reductase;
            hydroxymethylglutaryl CoA reductase (NADPH);
            S-3-hydroxy-3-methylglutaryl-CoA reductase;
            NADPH-hydroxymethylglutaryl-CoA reductase;
            HMGCoA reductase-mevalonate:NADP-oxidoreductase (acetylating-CoA);
            3-hydroxy-3-methylglutaryl CoA reductase (NADPH);
            hydroxymethylglutaryl-CoA reductase (NADPH2)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-mevalonate:NADP+ oxidoreductase (CoA-acylating)
REACTION    (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA
            + 2 NADPH + 2 H+ [RN:R02082]
ALL_REAC    R02082
SUBSTRATE   (R)-mevalonate [CPD:C00418];
            CoA [CPD:C00010];
            NADP+ [CPD:C00006]
PRODUCT     (S)-3-hydroxy-3-methylglutaryl-CoA [CPD:C00356];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
INHIBITOR   Pravastatin [CPD:C01844]
COMMENT     The enzyme is inactivated by EC 2.7.11.31
            {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} and
            reactivated by EC 3.1.3.47 {[hydroxymethylglutaryl-CoA reductase
            (NADPH)]-phosphatase}.
REFERENCE   1
  AUTHORS   Bucher, N.L.R., Overath, P. and Lynen, F.
  TITLE     beta-Hydroxy-beta-methylglutaryl coenzyme A reductase, cleavage and
            condensing enzymes in relation to cholesterol formation in rat
            liver.
  JOURNAL   Biochim. Biophys. Acta 40 (1960) 491-501.
REFERENCE   2  [PMID:13818862]
  AUTHORS   DURR IF, RUDNEY H.
  TITLE     The reduction of beta-hydroxy-beta-methyl-glutaryl coenzyme A to
            mevalonic acid.
  JOURNAL   J. Biol. Chem. 235 (1960) 2572-8.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
REFERENCE   3  [PMID:4985697]
  AUTHORS   Kawachi T, Rudney H.
  TITLE     Solubilization and purification of beta-hydroxy-beta-methylglutaryl
            coenzyme A reductase from rat liver.
  JOURNAL   Biochemistry. 9 (1970) 1700-5.
  ORGANISM  Rattus norvegicus [GN:rno]
PATHWAY     ec00900  Terpenoid backbone biosynthesis
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00021  hydroxymethylglutaryl-CoA reductase (NADPH)
GENES       HSA: 3156(HMGCR)
            PTR: 471516(HMGCR)
            PON: 100173499(HMGCR)
            MCC: 705479(HMGCR)
            MMU: 15357(Hmgcr)
            RNO: 25675(Hmgcr)
            CFA: 479182(HMGCR)
            AML: 100464316(HMGCR)
            BTA: 407159(HMGCR)
            SSC: 100144446(HMGR)
            ECB: 100065577
            MDO: 100014439
            GGA: 395145(HMGCR)
            TGU: 100228972
            XLA: 397750(hmgcr)
            XTR: 100380121(hmgcr)
            DRE: 541479(hmgcrb) 559054(hmgcra) 796384
            BFO: BRAFLDRAFT_57278
            CIN: 100187175
            SPU: 373355(HMGCR)
            DME: Dmel_CG10367(Hmgcr)
            DPO: Dpse_GA10278
            DAN: Dana_GF16258
            DER: Dere_GG11225
            DPE: Dper_GL23258
            DSE: Dsec_GM26526
            DWI: Dwil_GK22403
            DYA: Dyak_GE10390
            DGR: Dgri_GH23594
            DMO: Dmoj_GI10363
            DVI: Dvir_GJ22582
            AGA: AgaP_AGAP002288
            AAG: AaeL_AAEL009311
            CQU: CpipJ_CPIJ004077
            AME: 550724(Hmgcr)
            NVI: 100117068(NV14819)
            TCA: 662673
            API: 100165462
            PHU: Phum_PHUM388720
            ISC: IscW_ISCW009466
            CEL: F08F8.2
            CBR: CBG15296
            BMY: Bm1_54020
            NVE: NEMVE_v1g211859
            HMG: 100215451
            TAD: TRIADDRAFT_37359
            ATH: AT1G76490(HMG1) AT2G17370(HMG2)
            POP: POPTR_595031 POPTR_798252 POPTR_820962 POPTR_829982
                 POPTR_831722 POPTR_834149
            RCU: RCOM_0612970 RCOM_1565000 RCOM_1602200
            VVI: 100243051 100245191 100265082
            OSA: 4346017 4347443
            SBI: SORBI_02g028630 SORBI_04g030030 SORBI_07g027480
            ZMA: 100191922 100274191 100280335 100383280
            PPP: PHYPADRAFT_173789 PHYPADRAFT_189945 PHYPADRAFT_76806
            SCE: YLR450W(HMG2) YML075C(HMG1)
            AGO: AGOS_AER152W
            KLA: KLLA0B04642g
            LTH: KLTH0D16786g
            PPA: PAS_chr2-2_0230
            VPO: Kpol_1001p4 Kpol_520p23
            ZRO: ZYRO0B14696g
            CGR: CAGL0L11506g
            DHA: DEHA2D09372g
            PIC: PICST_72872(HMG1)
            PGU: PGUG_04712
            LEL: LELG_01348
            CAL: CaO19.1031(HMG1)
            CTP: CTRG_04347
            CDU: CD36_03520
            YLI: YALI0E04807g
            CLU: CLUG_04490
            NCR: NCU00712
            PAN: PODANSg09736
            MGR: MGG_08975(MG08975.4)
            FGR: FG09197.1
            SSL: SS1G_06018
            BFU: BC1G_01518
            ANI: AN3817.2
            AFM: AFUA_1G11230 AFUA_2G03700
            NFI: NFIA_014400 NFIA_036050
            AOR: AO090103000311 AO090120000217
            ANG: An07g08280
            AFV: AFLA_092010
            ACT: ACLA_090820
            PCS: Pc18g05230
            CIM: CIMG_04488
            CPW: CPC735_072790
            URE: UREG_01707
            PNO: SNOG_09830
            TML: GSTUM_00009050001
            SPO: SPCC162.09c(hmg1)
            CNE: CNF04830
            CNB: CNBF0070
            LBC: LACBIDRAFT_165672 LACBIDRAFT_184183
            MPR: MPER_15512
            CCI: CC1G_05275
            SCM: SCHCODRAFT_78529
            UMA: UM03014.1
            MGL: MGL_3624
            ECU: ECU10_1720
            MBR: MONBRDRAFT_32700
            NGR: NAEGRDRAFT_81695
            DDI: DDB_G0269142(hmgA) DDB_G0276615(hmgB)
            TBR: Tb927.6.4540
            TCR: 506831.40 509167.20
            LMA: LmjF30.3190
            LIF: LinJ30.3600
            LBZ: LbrM30_V2.3180
            TVA: TVAG_056640
            PTI: PHATRDRAFT_16870
            TPS: THAPSDRAFT_33680
            PAY: PAU_02226
            VCH: VCA0723
            VCO: VC0395_0662
            VCM: VCM66_A0681(hmgA)
            VCJ: VCD_000596
            VVU: VV2_0117
            VVY: VVA0625
            VVM: VVM_01267
            VPA: VPA0968
            VHA: VIBHAR_05704
            VSP: VS_II0457
            VEX: VEA_000087
            VFI: VF_A0841
            VFM: VFMJ11_A0972
            VSA: VSAL_II0253
            PAT: Patl_0427
            AMC: MADE_03398 MADE_03508
            CBU: CBU_0030 CBU_0610
            CBS: COXBURSA331_A0723(hmgA) COXBURSA331_A2174
            CBD: CBUD_0151 CBUD_0622(hmgA)
            CBG: CbuG_0298 CbuG_1393(hmgA)
            CBC: CbuK_0218 CbuK_1440(hmgA)
            TCX: Tcr_1717
            DNO: DNO_0797
            GPB: HDN1F_32470
            CVI: CV_1806
            LAS: CLIBASIA_04615
            LSO: CKC_03800
            PBR: PB2503_02617
            MUL: MUL_3522
            MMI: MMAR_3214
            CKP: ckrop_0031(mvaA)
            NFA: nfa22110
            SUS: Acid_5728 Acid_6132
            SRU: SRU_2422
            SRM: SRM_02640(hmgA)
            MTT: Ftrac_1626
            STR: Sterm_1947
            MJA: MJ_0705
            MFE: Mefer_1084
            MVU: Metvu_1468
            MFS: MFS40622_1470
            MIF: Metin_1136
            MMP: MMP0087(hmgA)
            MMQ: MmarC5_1589
            MMX: MmarC6_0860
            MMZ: MmarC7_1086
            MAE: Maeo_0718
            MVN: Mevan_1099
            MVO: Mvol_1440
            MAC: MA3073(hmgA)
            MBA: Mbar_A1972
            MMA: MM_0335
            MBU: Mbur_1098
            MMH: Mmah_0566
            MEV: Metev_1366
            MHU: Mhun_3004
            MLA: Mlab_1655
            MEM: Memar_2365
            MPI: Mpet_0546
            MBN: Mboo_0137
            MPL: Mpal_2647
            MPD: MCP_3002(hmgA-2)
            MTH: MTH562
            MMG: MTBMA_c09500(hmgA)
            MST: Msp_0584(hmgA)
            MSI: Msm_0227
            MRU: mru_1092(hmgA)
            MFV: Mfer_0012
            MKA: MK0355(HMG1)
            HAL: VNG1875G(mvaA)
            HSL: OE3637R(hmgR)
            HMA: rrnAC3412(mvaA)
            HWA: HQ3215A(hmgR)
            NPH: NP0368A(mvaA_2) NP2422A(mvaA_1)
            HLA: Hlac_2019
            HUT: Huta_0276
            HMU: Hmuk_1499
            HTU: Htur_0537
            NMG: Nmag_2929
            HVO: HVO_2583(hmgA)
            HJE: HacjB3_06610
            HBO: Hbor_10010
            PHO: PH1805
            PAB: PAB2106(mvaA)
            PFU: PF1848
            TKO: TK0914
            TON: TON_0399
            TGA: TGAM_1146(hmgA)
            TSI: TSIB_0612
            TBA: TERMP_00401
            RCI: RCIX1027(hmgA)
            APE: APE_1869(hmgA)
            SMR: Smar_1337
            SHC: Shell_1110
            IHO: Igni_0476
            HBU: Hbut_1531
            SSO: SSO0531
            STO: ST1352
            SAI: Saci_1359
            SIS: LS215_1692
            SIA: M1425_1584
            SIM: M1627_1700
            SID: M164_1581
            SIY: YG5714_1588
            SIN: YN1551_1248
            SII: LD85_1792
            MSE: Msed_1649
            PAI: PAE2182
            PIS: Pisl_0814
            PCL: Pcal_1085
            PAS: Pars_0796
            CMA: Cmaq_0412
            TNE: Tneu_1359
            VDI: Vdis_1666
            ASC: ASAC_1038
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.34
            IUBMB Enzyme Nomenclature: 1.1.1.34
            ExPASy - ENZYME nomenclature database: 1.1.1.34
            BRENDA, the Enzyme Database: 1.1.1.34
            CAS: 9028-35-7
///
ENTRY       EC 1.1.1.35                 Enzyme
NAME        3-hydroxyacyl-CoA dehydrogenase;
            beta-hydroxyacyl dehydrogenase;
            beta-keto-reductase;
            3-keto reductase;
            3-hydroxyacyl coenzyme A dehydrogenase;
            beta-hydroxyacyl-coenzyme A synthetase;
            beta-hydroxyacylcoenzyme A dehydrogenase;
            beta-hydroxybutyrylcoenzyme A dehydrogenase;
            3-hydroxyacetyl-coenzyme A dehydrogenase;
            L-3-hydroxyacyl coenzyme A dehydrogenase;
            L-3-hydroxyacyl CoA dehydrogenase;
            beta-hydroxyacyl CoA dehydrogenase;
            3beta-hydroxyacyl coenzyme A dehydrogenase;
            3-hydroxybutyryl-CoA dehydrogenase;
            beta-ketoacyl-CoA reductase;
            beta-hydroxy acid dehydrogenase;
            3-L-hydroxyacyl-CoA dehydrogenase;
            3-hydroxyisobutyryl-CoA dehydrogenase;
            1-specific DPN-linked beta-hydroxybutyric dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase
REACTION    (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+ [RN:R01778]
ALL_REAC    R01778 > R01975 R04203 R04737 R04739 R04741 R04743 R04745 R04748
            R04810 R04812 R06941 R07890 R07894 R07898;
            (other) R05066 R05575 R08094
SUBSTRATE   (S)-3-hydroxyacyl-CoA [CPD:C00640];
            NAD+ [CPD:C00003]
PRODUCT     3-oxoacyl-CoA [CPD:C00264];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and
            S-3-hydroxyacyl-hydrolipoate. Some enzymes act, more slowly, with
            NADP+. Broad specificity to acyl chain-length (cf. EC 1.1.1.211
            [long-chain-3-hydroxyacyl-CoA dehydrogenase]).
REFERENCE   1
  AUTHORS   Hillmer, P. and Gottschalk, G.
  TITLE     Solubilization and partial characterisation of particulate
            dehydrogenases from Clostridium kluyveri.
  JOURNAL   Biochim. Biophys. Acta 334 (1974) 12-23.
REFERENCE   2  [PMID:13115428]
  AUTHORS   LEHNINGER AL, GREVILLE GD.
  TITLE     The enzymic oxidation of alpha- and 2-beta-hydroxybutyrate.
  JOURNAL   Biochim. Biophys. Acta. 12 (1953) 188-202.
  ORGANISM  Rattus norvegicus [GN:rno]
REFERENCE   3  [PMID:13499396]
  AUTHORS   STERN JR.
  TITLE     Crystalline beta-hydroxybutyryl dehydrogenase from pig heart.
  JOURNAL   Biochim. Biophys. Acta. 26 (1957) 448-9.
  ORGANISM  Sus scofa [GN:ssc]
REFERENCE   4  [PMID:13163047]
  AUTHORS   WAKIL SJ, GREEN DE, MII S, MAHLER HR.
  TITLE     Studies on the fatty acid oxidizing system of animal tissues. VI.
            beta-Hydroxyacyl coenzyme A dehydrogenase.
  JOURNAL   J. Biol. Chem. 207 (1954) 631-8.
  ORGANISM  Bos taurus [GN:bta]
PATHWAY     ec00062  Fatty acid elongation in mitochondria
            ec00071  Fatty acid metabolism
            ec00120  Primary bile acid biosynthesis
            ec00280  Valine, leucine and isoleucine degradation
            ec00281  Geraniol degradation
            ec00310  Lysine degradation
            ec00380  Tryptophan metabolism
            ec00623  Toluene degradation
            ec00650  Butanoate metabolism
            ec00930  Caprolactam degradation
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00022  3-hydroxyacyl-CoA dehydrogenase
            K01782  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase /
                    3-hydroxybutyryl-CoA epimerase
            K01825  3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase /
                    3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase
            K07514  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /
                    3,2-trans-enoyl-CoA isomerase
            K07516  3-hydroxyacyl-CoA dehydrogenase
            K07547  2-[hydroxy(phenyl)methyl]-succinyl-CoA dehydrogenase BbsC
                    subunit
            K07548  2-[hydroxy(phenyl)methyl]-succinyl-CoA dehydrogenase BbsD
                    subunit
            K08683  3-hydroxyacyl-CoA dehydrogenase /
                    3-hydroxy-2-methylbutyryl-CoA dehydrogenase
            K10527  enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase
            K12405  3-hydroxyacyl-CoA dehydrogenase /
                    3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase
GENES       HSA: 1962(EHHADH) 3028(HSD17B10) 3033(HADH) 3295(HSD17B4)
            PTR: 460996(EHHADH) 461424(HADH) 462019(HSD17B4) 465649(HSD17B10)
            PON: 100174685(EHHADH) 100447416 100448539 100459385
            MCC: 696181(HADH) 698369(HSD17B4) 700018(HSD17B10) 701193(EHHADH)
            MMU: 15107(Hadh) 15108(Hsd17b10) 15488(Hsd17b4) 74147(Ehhadh)
            RNO: 113965(Hadh) 171142(Ehhadh) 63864(Hsd17b10) 79244(Hsd17b4)
            CFA: 474630(HSD17B4) 478506(HADH) 480930(HSD17B10) 488110(EHHADH)
            AML: 100466232 100468058 100471749(HSD17B4) 100483379
            BTA: 281809(HSD17B10) 493643(HSD17B4) 518852(EHHADH) 532785(HADH)
            SSC: 100524293 397574(HSD17B4) 397604(HADH)
            ECB: 100034046 100060335 100067714(EHHADH) 100072956
            MDO: 100010946 100019657 100028098(HSD17B4)
            OAA: 100080904 100081754(HSD17B4) 100081790 100082172(EHHADH)
            GGA: 395785(HSD17B4) 420290(HADH) 424877(EHHADH) 425758(HSD17B10)
            TGU: 100218671 100228698 100231239
            XLA: 380594(hadh) 444492(hsd17b4) 446903(hsd17b10)
            XTR: 100216115(ehhadh) 496484(hadh) 549265(hsd17b10) 613082(hsd17b4)
            DRE: 100000859(ehhadh) 393105(hsd17b4) 445121(hadh) 450078(hsd17b10)
            BFO: BRAFLDRAFT_125738 BRAFLDRAFT_220780 BRAFLDRAFT_291364
                 BRAFLDRAFT_66113
            CIN: 100180343 100182913 100187421 100187496
            SPU: 579135 581580 582126
            DME: Dmel_CG3415 Dmel_CG7113(scu)
            DPO: Dpse_GA17436 Dpse_GA20113
            DAN: Dana_GF19024 Dana_GF19368
            DER: Dere_GG17944 Dere_GG19147
            DPE: Dper_GL14944 Dper_GL15827
            DSE: Dsec_GM22877
            DSI: Dsim_GD17383
            DWI: Dwil_GK25326 Dwil_GK25668
            DYA: Dyak_GE17252 Dyak_GE17707
            DGR: Dgri_GH12555 Dgri_GH24783
            DMO: Dmoj_GI11209 Dmoj_GI14682
            DVI: Dvir_GJ16589 Dvir_GJ18503
            AGA: AgaP_AGAP003414 AgaP_AGAP008667
            AAG: AaeL_AAEL002841 AaeL_AAEL007023 AaeL_AAEL009324
            CQU: CpipJ_CPIJ001576 CpipJ_CPIJ006479 CpipJ_CPIJ014285
            AME: 409986 725274
            NVI: 100114736(NV10288) 100123018(NV16550)
            TCA: 660648 661810 663655(17-beta-HD4)
            API: 100164493 100167575 100169569(Hadh)
            PHU: Phum_PHUM268940 Phum_PHUM414590 Phum_PHUM489260
            ISC: IscW_ISCW005296 IscW_ISCW014460 IscW_ISCW018873
            CEL: B0272.3 F01G10.2(ech-8) F01G10.3(ech-9) F01G4.2(ard-1) F54C8.1
                 R09B5.6(hacd-1)
            CBR: CBG03387(Cbr-ech-8) CBG03388(Cbr-ech-9) CBG06017(Cbr-ard-1)
                 CBG10094 CBG10899(Cbr-dhs-28) CBG13089(Cbr-maoc-1) CBG16139
            BMY: Bm1_06360 Bm1_14640 Bm1_21570 Bm1_24050 Bm1_44740
            SMM: Smp_151030
            NVE: NEMVE_v1g163220 NEMVE_v1g200530 NEMVE_v1g217427
            HMG: 100198712 100208540 100209647
            TAD: TRIADDRAFT_19721 TRIADDRAFT_22420 TRIADDRAFT_51183
                 TRIADDRAFT_63801
            ATH: AT3G06860(MFP2) AT4G29010(AIM1)
            VVI: 100262653
            OSA: 4326503 4328997
            OLU: OSTLU_49128
            FGR: FG00090.1
            ANI: AN7238.2
            AOR: AO090009000113
            ANG: An12g03260 An19g00140
            AFV: AFLA_040900
            PCS: Pc19g00460
            CNE: CNC03600 CNH00460 CNI02410
            CNB: CNBC3610 CNBH2290 CNBL0440
            UMA: UM01099.1 UM03275.1
            MGL: MGL_2947
            MBR: MONBRDRAFT_23152 MONBRDRAFT_34126 MONBRDRAFT_35161
            NGR: NAEGRDRAFT_79710
            DDI: DDB_G0272128
            CHO: Chro.30048
            TGO: TGME49_034570
            TET: TTHERM_00016060 TTHERM_00085280 TTHERM_00085290 TTHERM_00085300
                 TTHERM_00085310
            PTM: GSPATT00031585001
            TBR: Tb927.2.4130
            TCR: 509717.90 510105.240
            LMA: LmjF24.2030 LmjF36.1140
            LIF: LinJ36.1490
            LBZ: LbrM35_V2.1270
            PTI: PHATRDRAFT_39681(HAD2)
            TPS: THAPSDRAFT_11182 THAPS_263178(HCD1)
            PIF: PITG_02607 PITG_05542 PITG_08061
            ECO: b2341(fadJ) b3846(fadB)
            ECJ: JW2338(yfcX) JW3822(fadB)
            ECD: ECDH10B_2504(fadJ) ECDH10B_4035(fadB)
            EBW: BWG_2113(fadJ) BWG_3522(fadB)
            ECE: Z3604(fadJ) Z5367(fadB)
            ECS: ECs3224(fadJ) ECs4774(fadB)
            ECF: ECH74115_3484(fadJ) ECH74115_5285(fadB)
            ETW: ECSP_3215(fadJ) ECSP_4899(fadB)
            EOJ: ECO26_3328(fadJ) ECO26_4741(fadB)
            EOI: ECO111_3088(fadJ) ECO111_4672(fadB)
            EOH: ECO103_2805(fadJ) ECO103_4319(fadB)
            ECG: E2348C_2480(fadJ) E2348C_4158(fadB)
            EOK: G2583_2877(fadJ) G2583_4644(fadB)
            ECC: c2886(fadJ) c4793(fadB)
            ECP: ECP_2379(fadJ) ECP_4059(fadB)
            ECI: UTI89_C2625(fadJ) UTI89_C4431(fadB)
            ECV: APECO1_2611(fadB) APECO1_4225(fadJ)
            ECX: EcHS_A2492(fadJ) EcHS_A4069(fadB)
            ECW: EcE24377A_2637(fadJ) EcE24377A_4365(fadB)
            ECM: EcSMS35_2500(fadJ) EcSMS35_4227(fadB)
            ECY: ECSE_2650(fadJ) ECSE_4132(fadB)
            ECR: ECIAI1_2418(fadJ) ECIAI1_4039(fadB)
            ECQ: ECED1_2804(fadJ) ECED1_4548(fadB)
            ECK: EC55989_2585(fadJ) EC55989_4321(fadB)
            ECT: ECIAI39_2493(fadJ) ECIAI39_3149(fadB)
            EUM: ECUMN_2680(fadJ) ECUMN_4370(fadB)
            ECZ: ECS88_2488(fadJ) ECS88_4294(fadB)
            ECL: EcolC_1312(fadJ) EcolC_4164(fadB)
            EBR: ECB_02265(fadJ) ECB_03737(fadB)
            EBD: ECBD_1319(fadJ) ECBD_4179(fadB)
            EFE: EFER_0823(fadJ) EFER_3635(fadB)
            STY: STY2620(fadJ) STY3577(fadB)
            STT: t0476(fadJ) t3315(fadB)
            STM: STM2388(fadJ) STM3983(fadB)
            SPT: SPA0476(fadJ) SPA3823(fadB)
            SEK: SSPA0440(fadJ) SSPA3560(fadB)
            SPQ: SPAB_00579(fadJ) SPAB_04939(fadB)
            SEI: SPC_1317(fadJ) SPC_4090(fadB)
            SEC: SC2390(fadJ) SC3880(fadB)
            SEH: SeHA_C2630(fadJ) SeHA_C4309(fadB)
            SEE: SNSL254_A2577(fadJ) SNSL254_A4262(fadB)
            SEW: SeSA_A2617(fadJ) SeSA_A4190(fadB)
            SEA: SeAg_B2528(fadJ) SeAg_B4213(fadB)
            SED: SeD_A2742(fadJ) SeD_A4369(fadB)
            SEG: SG2418(fadJ) SG3469(fadB)
            SET: SEN2370(fadJ) SEN3777(fadB)
            SES: SARI_00511(fadJ) SARI_03676(fadB)
            YPE: YPO2747(fadJ) YPO3766(fadB)
            YPK: y0464(fadB) y1580(fadJ)
            YPA: YPA_2097(fadJ) YPA_3436(fadB)
            YPN: YPN_0198(fadB) YPN_2200(fadJ)
            YPM: YP_2417(fadJ) YP_3282(fadB)
            YPP: YPDSF_2013(fadJ) YPDSF_3386(fadB)
            YPG: YpAngola_A0382(fadJ) YpAngola_A1912(fadB)
            YPZ: YPZ3_2556(faoA) YPZ3_3324(fadB)
            YPS: YPTB0267(fadB) YPTB2636(fadJ)
            YPI: YpsIP31758_0283(fadB) YpsIP31758_1400(fadJ)
            YPY: YPK_1509(fadJ) YPK_3933(fadB)
            YPB: YPTS_0283(fadB) YPTS_2733(fadJ)
            YEN: YE0268(fadB) YE1277(fadJ)
            SFL: SF2419(fadJ) SF3922(fadB)
            SFX: S2554(fadJ) S3830(fadB)
            SFV: SFV_2409(fadJ) SFV_3654(fadB)
            SSN: SSON_2397(fadJ) SSON_4019(fadB)
            SBO: SBO_2379(fadJ)
            SBC: SbBS512_E2721(fadJ) SbBS512_E4316(fadB)
            SDY: SDY_2542(fadJ) SDY_3899(fadB)
            ECA: ECA0208(fadB) ECA3078(fadJ)
            PCT: PC1_2821 PC1_4044
            PWA: Pecwa_1444(fadJ) Pecwa_4234(fadB)
            ETA: ETA_02460(fadB) ETA_11500(fadJ)
            EPY: EpC_02330(fadB) EpC_12010(fadJ)
            EAM: EAMY_0223(fadB) EAMY_2433(fadJ)
            EAY: EAM_0213(fadB) EAM_2346(fadJ)
            EBI: EbC_02440(fadB) EbC_31380(fadJ)
            PLU: plu3200(fadJ) plu4402(fadB)
            PAY: PAU_01417(fadJ) PAU_03873(fadB)
            ENT: Ent638_2881(fadJ) Ent638_3949(fadB)
            ENC: ECL_03682 ECL_04951
            ESC: Entcl_1392 Entcl_4192
            ESA: ESA_00882(fadJ) ESA_03714(fadB)
            CTU: Ctu_02770(fadB) Ctu_29620(fadJ)
            KPN: KPN_02723(fadJ) KPN_04340(fadB)
            KPE: KPK_1416(fadJ) KPK_5333(fadB)
            KPU: KP1_0203(fadB) KP1_3973(fadJ)
            KVA: Kvar_1326 Kvar_4892
            CKO: CKO_00188(fadB) CKO_00449(fadJ)
            CRO: ROD_27451(fadJ) ROD_39091(fadB)
            SPE: Spro_0261(fadB) Spro_3378(fadJ)
            PMR: PMI1807(fadJ) PMI3550(fadB)
            DDA: Dd703_2597 Dd703_3747(fadB)
            DDC: Dd586_0200 Dd586_2799
            DDD: Dda3937_00489(yfcX) Dda3937_02077(fadB)
            DZE: Dd1591_1341 Dd1591_3901(fadB)
            XBO: XBJ1_0517(fadB) XBJ1_2992(fadJ)
            XNE: XNC1_3194(fadJ) XNC1_3875(fadB)
            PAM: PANA_0201(fadB) PANA_2693(fadJ)
            PVA: Pvag_2148(fadJ) Pvag_3442(fadB)
            PAO: Pat9b_0194 Pat9b_2786
            HAP: HAPS_0676(fadJ)
            APL: APL_0888(fadJ)
            APJ: APJL_0900(fadJ)
            APA: APP7_0947
            XCC: XCC1266(fadB) XCC1979(fadB)
            XCB: XC_2205 XC_2975
            XCA: xccb100_2278(fadB2) xccb100_3037(fadB3)
            XCV: XCV1369(fadB) XCV2064(fadB)
            XAC: XAC1318(fadB) XAC2013(fadB)
            XOO: XOO1848(fadB) XOO2537(fadB)
            XOM: XOO_1744 XOO_2395
            XOP: PXO_01050 PXO_01709
            XAL: XALc_1594(fadB) XALc_2548(fadJ)
            SML: Smlt2052 Smlt3556
            SMT: Smal_1654 Smal_2982
            PSU: Psesu_1392 Psesu_1994
            VCH: VC1047(fadJ) VC2758(fadB)
            VCO: VC0395_A0565(fadJ) VC0395_A2534(fadB)
            VCM: VCM66_1002(fadJ) VCM66_2678(fadB)
            VCJ: VCD_001454(fadB) VCD_003295(fadJ)
            VVU: VV1_0981(fadB) VV1_1976(fadJ)
            VVY: VV0029(fadB) VV2440(fadJ)
            VVM: VVM_01692 VVM_04535
            VPA: VP0030(fadB) VP2208(fadJ)
            VHA: VIBHAR_00460(fadB) VIBHAR_03120(fadJ)
            VSP: VS_0041(fadB) VS_0865(fadJ)
            VEX: VEA_001988 VEA_002857
            VFI: VF_0025(fadB) VF_1810(fadJ)
            VFM: VFMJ11_0024(fadB) VFMJ11_1943(fadJ)
            VSA: VSAL_I2974(fadB)
            PPR: PBPRA0064(fadB) PBPRA0962(fadJ)
            PAE: PA1737 PA3014(faoA)
            PAU: PA14_25080(fadB) PA14_42080(fadB)
            PAP: PSPA7_2145(fadB) PSPA7_3568
            PAG: PLES_20481(fadB) PLES_35921
            PPU: PP_2136(fadB)
            PPF: Pput_3606(fadB)
            PPG: PputGB1_1676(fadB)
            PPW: PputW619_1652(fadB)
            PST: PSPTO_3517(fadB)
            PSB: Psyr_3290(fadB)
            PSP: PSPPH_3210(fadB)
            PFL: PFL_1479 PFL_1836(fadB) PFL_1940(fadB)
            PFO: Pfl01_1740 Pfl01_2754 Pfl01_3879(fadB)
            PFS: PFLU1553(fadB) PFLU4661
            PEN: PSEEN3728(fadB)
            PMY: Pmen_1580(fadB) Pmen_2590
            PSA: PST_0099 PST_1726(fadB)
            AVN: Avin_14440(fadB) Avin_17350
            PAR: Psyc_1399 Psyc_1934(fadB)
            PCR: Pcryo_1539 Pcryo_2227(fadB)
            PRW: PsycPRwf_1185 PsycPRwf_2100(fadB)
            ACI: ACIAD0335(fadB) ACIAD2989
            ACD: AOLE_02960 AOLE_17905(fadB)
            ACB: A1S_2854
            ABM: ABSDF0590 ABSDF3220(fadB)
            ABY: ABAYE0628 ABAYE3470(fadB)
            ABC: ACICU_00322(fadB) ACICU_03101
            ABN: AB57_0387(fadB) AB57_3357
            ABB: ABBFA_000607 ABBFA_003230(fadB)
            MCT: MCR_0091(fadB)
            SON: SO_0021(fadB) SO_3088(fadJ)
            SDN: Sden_0015(fadB) Sden_1530(fadJ)
            SFR: Sfri_0013(fadB) Sfri_2676(fadJ)
            SAZ: Sama_0032(fadB) Sama_2167(fadJ)
            SBL: Sbal_0021(fadB) Sbal_2760(fadJ)
            SBM: Shew185_0016(fadB) Shew185_2780(fadJ)
            SBN: Sbal195_0020(fadB) Sbal195_2855(fadJ)
            SBP: Sbal223_0020(fadB) Sbal223_1598(fadJ)
            SLO: Shew_0019(fadB) Shew_2425(fadJ) Shew_2864
            SPC: Sputcn32_0013(fadB) Sputcn32_2459(fadJ)
            SSE: Ssed_0023(fadB) Ssed_1629(fadJ)
            SPL: Spea_0018(fadB) Spea_2598(fadJ)
            SHE: Shewmr4_0018(fadB) Shewmr4_1408(fadJ)
            SHM: Shewmr7_0016(fadB) Shewmr7_1473(fadJ)
            SHN: Shewana3_0024(fadB) Shewana3_1461(fadJ)
            SHW: Sputw3181_0013(fadB) Sputw3181_1549(fadJ)
            SHL: Shal_0016(fadB) Shal_2670(fadJ)
            SWD: Swoo_0021(fadB) Swoo_0214 Swoo_3026(fadJ)
            SWP: swp_0035(fadB) swp_3139(fadJ)
            SVO: SVI_0052(fadB-1) SVI_2905(fadB-2)
            ILO: IL0011(fadB) IL0993(fadJ)
            CPS: CPS_0393(fadB) CPS_3156(fadJ)
            PHA: PSHAa0011(fadB) PSHAa0967(fadJ)
            PAT: Patl_0201(fadB) Patl_1664(fadJ) Patl_1916
            PSM: PSM_A0012(fadB) PSM_A1037(fadJ)
            SDE: Sde_1605(fadB)
            MAQ: Maqu_1144(fadB) Maqu_2490
            AMC: MADE_02318 MADE_02700(fadJ) MADE_03736(fadB)
            PIN: Ping_2604
            TTU: TERTU_1620(fadB)
            FBL: Fbal_0012 Fbal_2630
            CBU: CBU_0576(yfcX)
            CBS: COXBURSA331_A0690
            CBD: CBUD_1487
            CBG: CbuG_1422(yfcX)
            CBC: CbuK_1262(yfcX)
            LPN: lpg1352(fadB) lpg1596(yfcX)
            LPF: lpl1305 lpl1429
            LPP: lpp1306 lpp1554
            LPC: LPC_0768(fadB) LPC_1023(yfcX)
            LPA: lpa_01996 lpa_02315(yfcX)
            LLO: LLO_1816(yfcX) LLO_2331(fadB)
            FTU: FTT_1530(fadB)
            FTF: FTF1530(fadB)
            FTW: FTW_0401
            FTL: FTL_0584
            FTH: FTH_0584(fadB)
            FTA: FTA_0618
            FTM: FTM_0368
            FTN: FTN_1438
            FPH: Fphi_1237
            NOC: Noc_0826 Noc_1733(fadJ)
            NHL: Nhal_2077 Nhal_2479
            NWA: Nwat_1383 Nwat_2284
            AEH: Mlg_2111 Mlg_2126
            HCH: HCH_02185(fadB) HCH_03409 HCH_04756(fadB)
            CSA: Csal_2393(fadB)
            HEL: HELO_1758(fadB)
            ABO: ABO_1566(fadB) ABO_1652(fadB)
            KKO: Kkor_0013(fadB) Kkor_1978
            MMW: Mmwyl1_1578(fadB)
            AHA: AHA_0139(fadB) AHA_2154(fadJ)
            ASA: ASA_2145(fadJ) ASA_4250(fadB)
            GPB: HDN1F_10070(fadB) HDN1F_30400
            CVI: CV_2720(fadB)
            LHK: LHK_01609(fadB)
            RSO: RSc0474 RSc1759
            RSC: RCFBP_11768(fadB) RCFBP_21010
            RSL: RPSI07_1802(fadB) RPSI07_2894
            RPI: Rpic_0349 Rpic_1447 Rpic_4929
            RPF: Rpic12D_0364 Rpic12D_1488 Rpic12D_3852
            REU: Reut_A0447 Reut_A1405 Reut_B3873
            REH: H16_A0461 H16_A1526 H16_B0724
            RME: Rmet_0386 Rmet_1855 Rmet_4582(fadB) Rmet_5511
            CTI: RALTA_A0404 RALTA_A1467(fadB)
            BMA: BMA0198 BMA1438
            BMV: BMASAVP1_A1928 BMASAVP1_A2747 BMASAVP1_A3485
            BML: BMA10229_A1822 BMA10229_A2331 BMA10229_A3376
            BMN: BMA10247_1201 BMA10247_2411 BMA10247_2730
            BPS: BPSL0063 BPSL0649 BPSL1424
            BPM: BURPS1710b_0287(fadB) BURPS1710b_0858(fadB) BURPS1710b_2455
            BPL: BURPS1106A_0073 BURPS1106A_0696 BURPS1106A_2333
            BPD: BURPS668_0075 BURPS668_0681 BURPS668_2294
            BPR: GBP346_A0608 GBP346_A2403 GBP346_A4262
            BTE: BTH_I0062 BTH_I0565 BTH_I2142
            BVI: Bcep1808_1838 Bcep1808_2826 Bcep1808_2976
            BUR: Bcep18194_A5207 Bcep18194_A6047 Bcep18194_A6221 Bcep18194_C7186
            BCN: Bcen_2108 Bcen_2265 Bcen_6173
            BCH: Bcen2424_1906 Bcen2424_2720
            BCM: Bcenmc03_1929 Bcenmc03_2747 Bcenmc03_2890
            BCJ: BCAL0716 BCAL0885 BCAL1979
            BAM: Bamb_1894 Bamb_2772 Bamb_2934
            BAC: BamMC406_1824 BamMC406_2638 BamMC406_2796
            BMU: Bmul_0424 Bmul_0579 Bmul_1368
            BMJ: BMULJ_01875(fadB) BMULJ_02682(fadB) BMULJ_02831(fadB)
            BXE: Bxe_A1391 Bxe_A2274 Bxe_A4037 Bxe_C0280
            BPH: Bphy_0386 Bphy_1028 Bphy_7224
            BPY: Bphyt_0662 Bphyt_1926 Bphyt_2736
            BGL: bglu_1g13710 bglu_1g30710 bglu_1g31980
            BGE: BC1002_0381 BC1002_1473 BC1002_1988
            BRH: RBRH_01798 RBRH_02089
            PNE: Pnec_0963
            BPE: BP0669
            BPA: BPP2341 BPP2343 BPP4217
            BBR: BB1792 BB1794 BB4805
            BPT: Bpet2962(fadB1) Bpet3411(fadB2) Bpet3413(fadB1)
            BAV: BAV2553(phbB)
            AXY: AXYL_03650 AXYL_04498 AXYL_04500(fadN) AXYL_04661(fadJ1)
                 AXYL_06691(fadJ3)
            RFR: Rfer_2386 Rfer_2595 Rfer_2754 Rfer_3517
            POL: Bpro_2573 Bpro_3016 Bpro_3956
            PNA: Pnap_1842 Pnap_3476
            AAV: Aave_2880 Aave_4087 Aave_4314
            AJS: Ajs_0594 Ajs_1684 Ajs_3739
            DIA: Dtpsy_0573 Dtpsy_2020 Dtpsy_3020
            VEI: Veis_1792 Veis_4457 Veis_4959
            DAC: Daci_1339 Daci_1393 Daci_3313
            VAP: Vapar_0812 Vapar_0844 Vapar_2925 Vapar_5874
            VPE: Varpa_0837 Varpa_0880 Varpa_3186
            CTT: CtCNB1_1297 CtCNB1_2954 CtCNB1_3763 CtCNB1_4204
            ADN: Alide_0677 Alide_1563 Alide_3290 Alide_3762
            MPT: Mpe_A0417 Mpe_A1775
            HAR: HEAR2837(yusL)
            MMS: mma_3090
            HSE: Hsero_0255(fadB)
            LCH: Lcho_0845 Lcho_4031
            TIN: Tint_1595 Tint_2601
            NEU: NE1528
            NET: Neut_0724
            NMU: Nmul_A0097
            EBA: c1A208(fadB) c2A313(bbsD) c2A314(bbsC) ebA2315
            AZO: azo0465(fadB1) azo0468(fadB2)
            DAR: Daro_1547 Daro_1549 Daro_2350(fadB)
            TMZ: Tmz1t_0807 Tmz1t_0809
            APP: CAP2UW1_3459 CAP2UW1_3462
            SLT: Slit_1856
            GCA: Galf_1860
            ANT: Arnit_1347
            GME: Gmet_1530 Gmet_1531 Gmet_2196
            GUR: Gura_1591
            GBM: Gbem_2126
            GEO: Geob_2429 Geob_2430
            GEM: GM21_2092
            BBA: Bd1836
            DOL: Dole_0155
            DAL: Dalk_3659
            DAT: HRM2_48410(fadB)
            ADE: Adeh_0358 Adeh_0408(fadJ)
            ACP: A2cp1_0388 A2cp1_0437(fadJ)
            AFW: Anae109_2877 Anae109_4162(fadJ)
            ANK: AnaeK_0386 AnaeK_0436(fadJ)
            MXA: MXAN_5136 MXAN_5371(fadJ) MXAN_6987(fadJ)
            SCL: sce0048(fadJ) sce7555
            HOH: Hoch_1658 Hoch_1660 Hoch_2339 Hoch_3456 Hoch_6697
            DBR: Deba_0086 Deba_1863
            RPR: RP560
            RTY: RT0547(fadB)
            RFE: RF_0890(fadB)
            RAK: A1C_04325
            PUB: SAR11_1333(fadB)
            MLO: mll4199 mlr5629
            MCI: Mesci_1071 Mesci_6001
            MES: Meso_0021 Meso_1524
            PLA: Plav_0465 Plav_1949
            SME: SMc02227(fadB)
            SMD: Smed_0144
            RHI: NGR_c01670(fadB) NGR_c26080
            ATU: Atu0503(fadB)
            ARA: Arad_0816(fadB2)
            AVI: Avi_0597(fadB)
            RET: RHE_CH00559(fadB2)
            REC: RHECIAT_CH0000632(fadB2)
            RLE: RL0594
            RLT: Rleg2_0216
            RLG: Rleg_0244
            BME: BMEII0497
            BMI: BMEA_B0772
            BMF: BAB2_0444
            BMB: BruAb2_0439(fadB)
            BMC: BAbS19_II04190
            BMS: BRA0793(fadB)
            BMT: BSUIS_B0785
            BOV: BOV_A0744(fadB)
            BCS: BCAN_B0807(fadJ)
            BMR: BMI_II787(fadB)
            OAN: Oant_4019 Oant_4031
            BJA: bll7821 blr1160(fadB) blr2428
            BRA: BRADO0981(pimF) BRADO6723
            BBT: BBta_0817 BBta_7074(pimF)
            RPA: RPA0818 RPA3717(pimF)
            RPB: RPB_1746 RPB_4604
            RPC: RPC_0735 RPC_2226
            RPD: RPD_0807 RPD_3553
            RPE: RPE_0674 RPE_3780
            RPT: Rpal_0887 Rpal_4238
            RPX: Rpdx1_0979 Rpdx1_1632
            NWI: Nwi_2993
            NHA: Nham_0357 Nham_1087
            OCA: OCAR_5223
            XAU: Xaut_0624 Xaut_0906 Xaut_0915 Xaut_4444
            AZC: AZC_2873 AZC_2973
            MEX: Mext_3241
            MEA: Mex_1p3452
            MDI: METDI4031
            MRD: Mrad2831_0006 Mrad2831_1058
            MET: M446_0234 M446_3281
            MPO: Mpop_3437
            MCH: Mchl_3565
            MNO: Mnod_3360 Mnod_5242 Mnod_5442
            BID: Bind_1755 Bind_3269
            MSL: Msil_1395(fadB) Msil_1742
            HDN: Hden_1403
            RVA: Rvan_0558 Rvan_0849 Rvan_2899
            CCR: CC_0076 CC_3189
            CCS: CCNA_00074 CCNA_03293
            CAK: Caul_0125 Caul_0813
            CSE: Cseg_0771
            PZU: PHZ_c3217
            BSB: Bresu_0610
            AEX: Astex_1079
            SIL: SPO0739 SPO0772 SPO2920(fabJ-1) SPOA0424(fabJ-2)
            SIT: TM1040_0360 TM1040_1562
            RSP: RSP_2196 RSP_3535
            RSH: Rsph17029_0871 Rsph17029_3178
            RSQ: Rsph17025_2296 Rsph17025_2834
            RSK: RSKD131_0512 RSKD131_3703
            RCP: RCAP_rcc00520(fadB)
            JAN: Jann_0676 Jann_2977
            RDE: RD1_3973(fadJ)
            PDE: Pden_2871 Pden_3225 Pden_4792
            DSH: Dshi_0835(fadJ) Dshi_3826
            MMR: Mmar10_0543 Mmar10_2653
            HNE: HNE_0672
            HBA: Hbal_0931
            SAL: Sala_3068
            SWI: Swit_0322 Swit_0828 Swit_3796
            SJP: SJA_C1-01440(ehhadh3) SJA_C1-02110 SJA_C1-03820(fadB)
                 SJA_C1-20800(fadB) SJA_C2-01730 SJA_C2-03840(fadB)
                 SJA_C2-03960(fadB)
            ELI: ELI_00320
            ACR: Acry_0006 Acry_0255
            RRU: Rru_A1309
            RCE: RC1_0547 RC1_1743(fadJ) RC1_1947
            MAG: amb2990
            AZL: AZL_a10860(fadB) AZL_a11100(fadB) AZL_c00480(fadB)
            PBR: PB2503_07067
            APB: SAR116_0556 SAR116_1179
            MGM: Mmc1_3556
            DIN: Selin_1409
            BSU: BSU32840(fadN)
            BSS: BSUW23_16060(fadN)
            BHA: BH3488
            BAN: BA_5249
            BAR: GBAA_5249
            BAT: BAS4877
            BAH: BAMEG_5303
            BAI: BAA_5281
            BAL: BACI_c50160(fadB)
            BCE: BC5004
            BCA: BCE_5144
            BCZ: BCZK4734(fadB)
            BCR: BCAH187_A5156
            BCB: BCB4264_A5150
            BCU: BCAH820_5118
            BCG: BCG9842_B0094
            BCQ: BCQ_4825(fadB)
            BCX: BCA_5154
            BCY: Bcer98_3597
            BTK: BT9727_4719(fadB)
            BTL: BALH_4547(fadB)
            BTB: BMB171_C4613
            BWE: BcerKBAB4_4835
            BLI: BL02180(yusL)
            BLD: BLi03466(yusL)
            BAY: RBAM_029920(yusL)
            BAO: BAMF_3124(fadN)
            BAE: BATR1942_14340
            BCL: ABC2990
            BPU: BPUM_2942
            BPF: BpOF4_05120
            BMQ: BMQ_5007(fadN)
            BMD: BMD_4992(fadN)
            BSE: Bsel_1140
            BCO: Bcell_3450
            OIH: OB2395
            GKA: GK3008
            GTN: GTNG_2960
            GWC: GWCH70_2937
            GYM: GYMC10_0260
            GYC: GYMC61_3088
            GYA: GYMC52_3113
            GCT: GC56T3_0495
            GMC: GY4MC1_0494
            SAU: SA0224
            SAV: SAV0232
            SAW: SAHV_0231
            SAH: SaurJH1_0222
            SAJ: SaurJH9_0216
            SAM: MW0208
            SAS: SAS0208
            SAR: SAR0224(fadB)
            SAC: SACOL0212
            SAX: USA300HOU_0241
            SAA: SAUSA300_0226
            SAO: SAOUHSC_00196
            SAE: NWMN_0168(fadB)
            SAD: SAAV_0197
            SAB: SAB0171c
            SSP: SSP2424
            SCA: Sca_2409
            SSD: SPSINT_2293
            LSP: Bsph_0533
            ESI: Exig_2354
            EAT: EAT1b_0817
            BBE: BBR47_48990(fadN)
            PJD: Pjdr2_0489
            AAC: Aaci_1594
            BTS: Btus_1056
            SDS: SDEG_1598
            STH: STH3012
            DSY: DSY3369
            DHD: Dhaf_4532
            DRM: Dred_0347
            HMO: HM1_0073
            TMR: Tmar_0897
            CHY: CHY_1609
            MTU: Rv0860(fadB)
            MTC: MT0883
            MRA: MRA_0868(fadB)
            MTF: TBFG_10877
            MTB: TBMG_03130(TBMG_03130.1)
            MBO: Mb0883(fadB)
            MBB: BCG_0912(fadB)
            MBT: JTY_0882(fadB)
            MLE: ML2161(fadB)
            MLB: MLBr_02161(fadB)
            MPA: MAP0790(fadB_1)
            MAV: MAV_0981
            MSM: MSMEG_5720
            MUL: MUL_0295(fadB)
            MVA: Mvan_5066
            MGI: Mflv_1692
            MAB: MAB_0851
            MMC: Mmcs_4492
            MKM: Mkms_4579
            MJL: Mjls_4875
            MSP: Mspyr1_10740
            MMI: MMAR_4676(fadB)
            CEF: CE0722
            CJK: jk0159(fadB1)
            CUR: cur_0178(fadB1)
            CAR: cauri_0585(fadB)
            CKP: ckrop_0257(fadB1)
            NFA: nfa2860(fadB)
            RHA: RHA1_ro04205(fadB1)
            RER: RER_03810(fadB)
            ROP: ROP_25300(fadB) ROP_26130(fadB) ROP_41320(fadB)
            REQ: REQ_03780
            GBR: Gbro_4503
            TPR: Tpau_4183
            SRT: Srot_2536
            SCO: SCO6732(SC5F2A.15)
            SMA: SAV_1680(fadB1)
            SGR: SGR_993
            SCB: SCAB_13351(fadB1)
            RSA: RSal33209_3440
            NCA: Noca_4562
            KFL: Kfla_3678
            FRA: Francci3_1329
            FRE: Franean1_2944
            FRI: FraEuI1c_5724
            FAL: FRAAL2096
            SEN: SACE_5040 SACE_6362(fadB)
            SVI: Svir_30240
            AMD: AMED_7893(fadB)
            AMI: Amir_4372 Amir_5669
            MAU: Micau_2142
            MIL: ML5_2247
            CAI: Caci_5261
            SNA: Snas_3890
            RXY: Rxyl_2057 Rxyl_2453
            CWO: Cwoe_1505
            WCH: wcw_1274(fadB)
            ABA: Acid345_2469
            ACA: ACP_1047(fadB)
            SUS: Acid_5546 Acid_5696
            SRU: SRU_1210 SRU_1459(yfcX)
            SRM: SRM_01398 SRM_01651(fadJ)
            RMR: Rmar_1469 Rmar_1707
            CHU: CHU_3591(fadB)
            DFE: Dfer_3526
            SLI: Slin_4424 Slin_6109
            LBY: Lbys_2827
            MTT: Ftrac_1686
            CPI: Cpin_7062
            PHE: Phep_3724
            GFO: GFO_1047
            FJO: Fjoh_4753
            FPS: FP1723
            RBI: RB2501_00411
            ZPR: ZPR_2469
            CAT: CA2559_06180
            RAN: Riean_0064
            FBC: FB2170_13963
            CAO: Celal_0104
            FBA: FIC_00946
            GAU: GAU_2755 GAU_2856(fadJ)
            RBA: RB1092(faoA)
            PSL: Psta_1892
            CYN: Cyan7425_3065
            AMR: AM1_2148
            RRS: RoseRS_2970
            RCA: Rcas_1887
            CAU: Caur_3221
            CAG: Cagg_0347
            CHL: Chy400_3477
            HAU: Haur_4394
            TRO: trd_A0098
            STI: Sthe_1473 Sthe_2923
            DRA: DR_1487 DR_2477
            DGE: Dgeo_0617 Dgeo_0754
            DDR: Deide_09650 Deide_17260
            DMR: Deima_0378 Deima_2296
            TRA: Trad_1406 Trad_2740
            TTH: TTC0534
            TTJ: TTHA0890
            TSC: TSC_c13200
            MRB: Mrub_1466
            MSV: Mesil_1798
            OPR: Ocepr_0933
            NDE: NIDE3103
            DDF: DEFDS_1467
            CNI: Calni_0350
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.35
            IUBMB Enzyme Nomenclature: 1.1.1.35
            ExPASy - ENZYME nomenclature database: 1.1.1.35
            UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.35
            BRENDA, the Enzyme Database: 1.1.1.35
            CAS: 9028-40-4
///
ENTRY       EC 1.1.1.36                 Enzyme
NAME        acetoacetyl-CoA reductase;
            acetoacetyl coenzyme A reductase;
            hydroxyacyl coenzyme-A dehydrogenase;
            NADP-linked acetoacetyl CoA reductase;
            NADPH:acetoacetyl-CoA reductase;
            D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase;
            short chain beta-ketoacetyl(acetoacetyl)-CoA reductase;
            beta-ketoacyl-CoA reductase;
            D-3-hydroxyacyl-CoA reductase;
            (R)-3-hydroxyacyl-CoA dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase
REACTION    (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+
            [RN:R01779]
ALL_REAC    R01779 > R01977
SUBSTRATE   (R)-3-hydroxyacyl-CoA [CPD:C01086];
            NADP+ [CPD:C00006]
PRODUCT     3-oxoacyl-CoA [CPD:C00264];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:14004466]
  AUTHORS   WAKIL S, BRESSLER R.
  TITLE     Studies on the mechanism of fatty acid synthesis. X. Reduced
            triphosphopyridine nucleotide-acetoacetyl coenzyme A reductase.
  JOURNAL   J. Biol. Chem. 237 (1962) 687-93.
  ORGANISM  pigeon
PATHWAY     ec00630  Glyoxylate and dicarboxylate metabolism
            ec00650  Butanoate metabolism
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00023  acetoacetyl-CoA reductase
GENES       CRO: ROD_12481
            XFA: XF0319(fabG)
            XFT: PD0262(fabG)
            XFM: Xfasm12_0283(fabG)
            XFN: XfasM23_0254(fabG)
            XCC: XCC2294(phbB) XCC3355(fabG)
            XCB: XC_0809(fabG) XC_1821
            XCA: xccb100_0842(fabG) xccb100_1884
            XCV: XCV2598(phbB) XCV3614(fabG)
            XAC: XAC2401(phbB) XAC3486(fabG)
            XOO: XOO1102(fabG) XOO2728(phbB)
            XOM: XOO_1000(fabG) XOO_2573
            XOP: PXO_00406 PXO_02411(fabG)
            XAL: XALc_1098(phbB)
            SML: Smlt3325(phbB) Smlt3952(fabG)
            SMT: Smal_2750 Smal_3362(fabG)
            PSU: Psesu_1356
            VCH: VCA0691
            VCO: VC0395_0631
            VCM: VCM66_A0649
            VCJ: VCD_000634
            VVU: VV2_0742
            VVY: VVA1211
            VVM: VVM_02299
            VPA: VPA1205
            VHA: VIBHAR_05365
            VSP: VS_II0584
            VEX: VEA_000520
            PPR: PBPRB0350(fabG) PBPRB1841
            PSA: PST_0685(phaB)
            AVN: Avin_23650(phbB)
            SON: SO_3263
            SAZ: Sama_2250
            CPS: CPS_2625(phbB1) CPS_4092(phbB2)
            SDE: Sde_1330
            MAQ: Maqu_3915
            TTU: TERTU_2753(phbB)
            FBL: Fbal_3526
            LPN: lpg0560(phaB) lpg0561(phaB) lpg1059(phaB)
            LPF: lpl0603 lpl0604 lpl1056 lpl2305
            LPP: lpp0620 lpp0621 lpp2322
            LPC: LPC_2098 LPC_2215(phaB) LPC_2738(phaB2) LPC_2739(phaB)
            LPA: lpa_00885 lpa_00889 lpa_01645(phaB) lpa_03464
            LLO: LLO_0418(fabG) LLO_0419(fabG) LLO_p0045(fabG)
            ALV: Alvin_0066
            AEH: Mlg_0994(fabG) Mlg_2486
            HHA: Hhal_0557 Hhal_2205
            TGR: Tgr7_1515 Tgr7_1519
            HCH: HCH_04996(phbB)
            CSA: Csal_3029
            HEL: HELO_3876(phbB)
            AHA: AHA_1951
            ASA: ASA_2343
            TAU: Tola_2469
            CVI: CV_2364(phaB)
            LHK: LHK_01110(phaB)
            RSO: RSc1633(phbB)
            RSC: RCFBP_10870(phaB) RCFBP_11641(phaB)
            RSL: RPSI07_0940(phaB) RPSI07_1726(phaB)
            RPI: Rpic_1914 Rpic_4412
            RPF: Rpic12D_1585 Rpic12D_4545
            REU: Reut_A1349 Reut_B3865 Reut_B4127 Reut_C6018
            REH: H16_A1439(phaB1) H16_A2002(phaB2) H16_A2171(phaB3)
            RME: Rmet_1333 Rmet_1358 Rmet_5123(phaB3)
            CTI: RALTA_A1352(phaB1) RALTA_A1758(phaB2)
            BMA: BMA1320(phbB-1) BMAA0166(phbB-2)
            BMV: BMASAVP1_1337(phbB-1) BMASAVP1_A1809(phbB-2)
            BML: BMA10229_A0087(phbB-1)
            BMN: BMA10247_1080(phbB-2) BMA10247_A0193(phbB-1)
            BPS: BPSL1536(phbB) BPSS1916(phbB)
            BPM: BURPS1710b_2329(phbB-1) BURPS1710b_A1014(phbB-2)
            BPL: BURPS1106A_2201(phbB) BURPS1106A_A2601(phbB)
            BPD: BURPS668_2164(phbB) BURPS668_A2744(phbB)
            BPR: GBP346_A2272(phbB)
            BTE: BTH_I2257 BTH_II0461
            BVI: Bcep1808_1716 Bcep1808_2876 Bcep1808_6164 Bcep1808_6330
            BUR: Bcep18194_A5090 Bcep18194_A6101
            BCN: Bcen_2157 Bcen_6290
            BCH: Bcen2424_1789 Bcen2424_2771
            BCM: Bcenmc03_1813 Bcenmc03_2782
            BCJ: BCAL0833(phbB) BCAL1861(phbB) BCAM0296(phbB)
            BAM: Bamb_1727 Bamb_2823 Bamb_3819
            BAC: BamMC406_1700 BamMC406_2690 BamMC406_4287
            BMU: Bmul_0544 Bmul_1485 Bmul_5756 Bmul_5895
            BMJ: BMULJ_01757(phbB) BMULJ_02716(phbB) BMULJ_05630(phbB)
                 BMULJ_05765(phbB)
            BXE: Bxe_A2341 Bxe_B0354
            BPH: Bphy_0971 Bphy_1131 Bphy_6555
            BPY: Bphyt_1845 Bphyt_5566
            BGL: bglu_1g14730 bglu_2g20290
            BGE: BC1002_1414 BC1002_6070 BC1002_6131
            BRH: RBRH_03709
            PNU: Pnuc_0924(fabG)
            PNE: Pnec_0917
            BPE: BP1150(fabG)
            BPA: BPP3195(fabG)
            BBR: BB3595(fabG)
            BPT: Bpet1850(fabG)
            BAV: BAV1222(fabG)
            AXY: AXYL_01381(phbB2) AXYL_01666(phbB3) AXYL_05665(phbB4)
            RFR: Rfer_2560(fabG)
            POL: Bpro_1198 Bpro_2141(fabG)
            PNA: Pnap_2803(fabG)
            AAV: Aave_2479(fabG)
            AJS: Ajs_2072(fabG)
            DIA: Dtpsy_1310 Dtpsy_1895(fabG)
            VEI: Veis_2347(fabG)
            DAC: Daci_3602(fabG)
            VAP: Vapar_2031(fabG) Vapar_5342
            VPE: Varpa_0734 Varpa_3856
            CTT: CtCNB1_2350
            ADN: Alide_2263 Alide_2843
            MPT: Mpe_A1868(fabG)
            HAR: HEAR0578(phbB) HEAR2345(phbB)
            MMS: mma_0556(phbB)
            HSE: Hsero_2998(phbB)
            LCH: Lcho_2085(fabG)
            TIN: Tint_1317
            EBA: ebA4729(phbB) ebA4731(adh)
            AZO: azo1022(phbB1) azo1023(phbB2)
            DAR: Daro_1609 Daro_1610
            TMZ: Tmz1t_1025 Tmz1t_3122 Tmz1t_3123
            APP: CAP2UW1_3919
            GBM: Gbem_1433(fabG-3)
            GEM: GM21_2821
            PCA: Pcar_1120
            RPR: RP035
            RTY: RT0095(phbB)
            RCO: RC0054(phbB)
            RFE: RF_0153(phbB)
            RAK: A1C_00095
            RRJ: RrIowa_0072
            RAF: RAF_ORF0048(phbB)
            RBE: RBE_1370(phbB)
            RBO: A1I_07605
            MLO: mlr3848
            MCI: Mesci_1328
            MES: Meso_3375
            PLA: Plav_1574 Plav_3449
            SME: SMc03878(phbB)
            SMD: Smed_3116
            RHI: NGR_c32710
            ATU: Atu2770(phbB)
            ARA: Arad_4680(phbB) Arad_8221(phbB)
            AVI: Avi_4345(phbB)
            RET: RHE_CH04019(phbB)
            REC: RHECIAT_CH0004307(phbB)
            RLE: RL4620(phaB)
            RLT: Rleg2_3821
            RLG: Rleg_4149
            BJA: bll0225(phbB) blr3725(phbB)
            BRA: BRADO0563(phbB)
            BBT: BBta_7613(phbB)
            RPA: RPA0532
            RPB: RPB_0508
            RPC: RPC_0505
            RPD: RPD_0305
            RPE: RPE_0167
            RPT: Rpal_0533
            RPX: Rpdx1_0562
            NWI: Nwi_3061
            NHA: Nham_3689
            OCA: OCAR_4106 OCAR_4863
            XAU: Xaut_3107
            AZC: AZC_0305
            SNO: Snov_2736
            MEX: Mext_3470
            MEA: Mex_1p3701(phaB)
            MDI: METDI4273(phaB)
            MRD: Mrad2831_5119
            MET: M446_1247 M446_5281
            MPO: Mpop_3668
            MCH: Mchl_3778
            MNO: Mnod_4780
            BID: Bind_0426
            MSL: Msil_2997
            HDN: Hden_2770
            RVA: Rvan_0022
            CCR: CC_0511
            CCS: CCNA_00545
            CAK: Caul_1946 Caul_4514
            CSE: Cseg_0393
            PZU: PHZ_c0432(phbB) PHZ_p0110(phbB)
            BSB: Bresu_0821
            AEX: Astex_0842
            SIL: SPO0325(phbB)
            SIT: TM1040_3736
            RSP: RSP_0747 RSP_3963
            RSH: Rsph17029_2402
            RSQ: Rsph17025_2467
            RSK: RSKD131_2105
            RCP: RCAP_rcc03179(phbB)
            JAN: Jann_0492
            RDE: RD1_3395(phbB)
            PDE: Pden_2027
            DSH: Dshi_3067(fabG1)
            MMR: Mmar10_2384
            HNE: HNE_3404(phbB)
            HBA: Hbal_2358
            NAR: Saro_3212
            SAL: Sala_2255
            SWI: Swit_4599
            SJP: SJA_C1-10300(phbB)
            ELI: ELI_12280
            GBE: GbCGDNIH1_0449
            ACR: Acry_2753
            GDI: GDI_3305
            GDJ: Gdia_3065
            RRU: Rru_A0273
            RCE: RC1_3949(phbB)
            MAG: amb0843
            AZL: AZL_023120(phbB)
            PBR: PB2503_01567
            MGM: Mmc1_1166
            BAN: BA_1330(fabG)
            BAR: GBAA_1330(fabG)
            BAT: BAS1230(fabG)
            BAH: BAMEG_3266(phbB)
            BAI: BAA_1397(phbB)
            BAL: BACI_c13500(fabG2)
            BCE: BC1317(fabG)
            BCA: BCE_1429(fabG)
            BCZ: BCZK1209(fabG)
            BCR: BCAH187_A1470(phbB)
            BCB: BCB4264_A1368(phbB)
            BCU: BCAH820_1405(phbB)
            BCG: BCG9842_B3976(phbB)
            BCQ: BCQ_1389(phaB)
            BCX: BCA_1368(phbB)
            BCY: Bcer98_1043
            BTK: BT9727_1207(fabG)
            BTL: BALH_1179(phaB)
            BTB: BMB171_C1160(phbB)
            BWE: BcerKBAB4_1231
            BMQ: BMQ_1230(phaB)
            BMD: BMD_1215(phaB)
            BTS: Btus_1590
            GOB: Gobs_2422
            RXY: Rxyl_2393(fabG)
            MAR: MAE_50050(phaB)
            CYN: Cyan7425_4055
            CYJ: Cyan7822_1327
            CAU: Caur_1462(fabG)
            CAG: Cagg_1951(fabG)
            CHL: Chy400_1585(fabG)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.36
            IUBMB Enzyme Nomenclature: 1.1.1.36
            ExPASy - ENZYME nomenclature database: 1.1.1.36
            UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.36
            BRENDA, the Enzyme Database: 1.1.1.36
            CAS: 9028-41-5
///
ENTRY       EC 1.1.1.37                 Enzyme
NAME        malate dehydrogenase;
            malic dehydrogenase;
            L-malate dehydrogenase;
            NAD-L-malate dehydrogenase;
            malic acid dehydrogenase;
            NAD-dependent malic dehydrogenase;
            NAD-malate dehydrogenase;
            NAD-malic dehydrogenase;
            malate (NAD) dehydrogenase;
            NAD-dependent malate dehydrogenase;
            NAD-specific malate dehydrogenase;
            NAD-linked malate dehydrogenase;
            MDH;
            L-malate-NAD+ oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-malate:NAD+ oxidoreductase
REACTION    (S)-malate + NAD+ = oxaloacetate + NADH + H+ [RN:R00342]
ALL_REAC    R00342
SUBSTRATE   (S)-malate [CPD:C00149];
            NAD+ [CPD:C00003]
PRODUCT     oxaloacetate [CPD:C00036];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also oxidizes some other 2-hydroxydicarboxylic acids.
REFERENCE   1
  AUTHORS   Banaszak, L.J. and Bradshaw, R.A.
  TITLE     Malate dehydrogenase.
  JOURNAL   In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 11, Academic
            Press, New York, 1975, p. 369-396.
REFERENCE   2  [PMID:5637713]
  AUTHORS   Guha A, Englard S, Listowsky I.
  TITLE     Beef heart malic dehydrogenases. VII. Reactivity of sulfhydryl
            groups and conformation of the supernatant enzyme.
  JOURNAL   J. Biol. Chem. 243 (1968) 609-15.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   3  [PMID:4313528]
  AUTHORS   McReynolds MS, Kitto GB.
  TITLE     Purification and properties of Drosophila malate dehydrogenases.
  JOURNAL   Biochim. Biophys. Acta. 198 (1970) 165-75.
  ORGANISM  Drosophila melanogaster [GN:dme], Drosophila virilis [GN:dvi]
REFERENCE   4  [PMID:13345798]
  AUTHORS   WOLFE RG, NEILANDS JB.
  TITLE     Some molecular and kinetic properties of heart malic dehydrogenase.
  JOURNAL   J. Biol. Chem. 221 (1956) 61-9.
  ORGANISM  Sus scofa [GN:ssc]
PATHWAY     ec00020  Citrate cycle (TCA cycle)
            ec00620  Pyruvate metabolism
            ec00630  Glyoxylate and dicarboxylate metabolism
            ec00680  Methane metabolism
            ec00710  Carbon fixation in photosynthetic organisms
            ec00720  Carbon fixation in prokaryotes
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00024  malate dehydrogenase
            K00025  malate dehydrogenase
            K00026  malate dehydrogenase
GENES       HSA: 4190(MDH1) 4191(MDH2)
            PTR: 459271(MDH1) 463484(MDH2)
            PON: 100174759(MDH2) 100454132(MDH1)
            MCC: 694703(MDH1) 719983
            MMU: 17448(Mdh2) 17449(Mdh1)
            RNO: 24551(Mdh1) 81829(Mdh2)
            CFA: 474614(MDH1) 482601 482945(MDH2) 485162
            AML: 100464508 100482261
            BTA: 281306(MDH2) 535182(MDH1)
            SSC: 396894(MDH1)
            ECB: 100051612 100061046(MDH2)
            MDO: 100018146 100031872
            OAA: 100082315
            GGA: 417517(MDH2) 421281(MDH1)
            TGU: 100190381 100190484
            XLA: 398872(mdh1) 443751(mdh2-b) 446263(mdh2-a)
            XTR: 448318(mdh1) 496892(mdh2)
            DRE: 335715(mdh1b) 399662(mdh1a) 406405(wu:fj48c08)
            BFO: BRAFLDRAFT_114460 BRAFLDRAFT_81385
            CIN: 100178529 100187217
            SPU: 587163 591635
            DME: Dmel_CG10748 Dmel_CG10749 Dmel_CG5362 Dmel_CG7998
            DPO: Dpse_GA10540 Dpse_GA10541 Dpse_GA20754
            DAN: Dana_GF10673 Dana_GF14102 Dana_GF23071 Dana_GF23749
            DER: Dere_GG13791 Dere_GG15612 Dere_GG22759 Dere_GG23937
            DPE: Dper_GL12005 Dper_GL19158 Dper_GL24873 Dper_GL25264
            DSE: Dsec_GM11692 Dsec_GM15290 Dsec_GM24618 Dsec_GM25384
            DSI: Dsim_GD12684 Dsim_GD14416 Dsim_GD19217 Dsim_GD22263
            DWI: Dwil_GK22135 Dwil_GK22161 Dwil_GK22386 Dwil_GK23502
            DYA: Dyak_GE20084 Dyak_GE21938 Dyak_GE25523 Dyak_GE25998
            DGR: Dgri_GH13357 Dgri_GH18558 Dgri_GH21421 Dgri_GH21422
            DMO: Dmoj_GI18261 Dmoj_GI18598 Dmoj_GI24757
            DVI: Dvir_GJ17520 Dvir_GJ20394 Dvir_GJ22544
            AGA: AgaP_AGAP001903 AgaP_AGAP009510
            AAG: AaeL_AAEL007707 AaeL_AAEL008166
            CQU: CpipJ_CPIJ002460 CpipJ_CPIJ008366
            AME: 408950 411014 552575 726838
            NVI: 100114033(NV17544) 100118243(NV15023) 100119291(NV16898)
            TCA: 662339 664447
            API: 100145825(Mdh2) 100163431
            PHU: Phum_PHUM590780
            ISC: IscW_ISCW003528 IscW_ISCW007624
            CEL: F20H11.3(mdh-1) F46E10.10
            CBR: CBG15213(Cbr-mdh-1) CBG18957
            BMY: Bm1_04060 Bm1_46465
            SMM: Smp_035270.1 Smp_035270.2 Smp_047370
            NVE: NEMVE_v1g185681 NEMVE_v1g248519
            HMG: 100208342 100208718 100210170
            TAD: TRIADDRAFT_63987
            ATH: AT1G04410 AT1G53240 AT2G22780(PMDH1) AT3G15020 AT3G47520(MDH)
                 AT5G09660(PMDH2) AT5G43330 AT5G56720
            POP: POPTR_551994 POPTR_551996 POPTR_564942 POPTR_583880
                 POPTR_649749 POPTR_707785 POPTR_747123 POPTR_758803
                 POPTR_785828 POPTR_798097 POPTR_820117 POPTR_822907
                 POPTR_837445
            RCU: RCOM_0339260 RCOM_0400230 RCOM_0400340 RCOM_1014110
                 RCOM_1381350 RCOM_1471880 RCOM_1520380 RCOM_1609380
            VVI: 100232859(MDH) 100247511 100248145 100253198 100253273
                 100253724 100256452 100260994 100265585
            OSA: 4326249 4327423 4334274 4336595 4339682 4343993 4345657 4348905
                 4352871
            SBI: SORBI_01g019280 SORBI_02g040190 SORBI_03g029570 SORBI_06g024610
                 SORBI_08g022770 SORBI_09g029240
            ZMA: 100193491(pco104294) 100193663 100193743(pco143139c) 100272900
                 100273428 100274264 100280767 100282134 542598(mdh5)
            PPP: PHYPADRAFT_118897 PHYPADRAFT_129976 PHYPADRAFT_131843
                 PHYPADRAFT_135701 PHYPADRAFT_143364 PHYPADRAFT_162162
                 PHYPADRAFT_195276 PHYPADRAFT_207351
            CRE: CHLREDRAFT_126023(MDH2) CHLREDRAFT_137163(MDH1)
                 CHLREDRAFT_158129(MDH3) CHLREDRAFT_60444(MDH4)
            VCN: VOLCADRAFT_75816(mdh3) VOLCADRAFT_77493(mdh1)
                 VOLCADRAFT_82979(mdh2)
            OLU: OSTLU_12282 OSTLU_24671 OSTLU_32875 OSTLU_87414
            OTA: Ot06g00180
            CME: CMP193C CMT611C
            SCE: YDL078C(MDH3) YKL085W(MDH1) YOL126C(MDH2)
            AGO: AGOS_ADL164C AGOS_ADR152C AGOS_ADR252W
            KLA: KLLA0E07525g KLLA0F17050g KLLA0F25960g
            LTH: KLTH0C01188g KLTH0E09614g KLTH0F18854g
            PPA: PAS_chr2-1_0238 PAS_chr4_0815
            VPO: Kpol_1020p28 Kpol_1041p28 Kpol_1073p7
            ZRO: ZYRO0A08470g ZYRO0C02684g ZYRO0E00880g
            CGR: CAGL0E01705g CAGL0L05236g CAGL0L06798g
            DHA: DEHA2B02596g DEHA2B03058g
            PIC: PICST_40132(MDHM) PICST_66451(MDH1) PICST_78343(MDH2)
            PGU: PGUG_01503 PGUG_02540 PGUG_02579
            LEL: LELG_00466 LELG_02620 LELG_04196
            CAL: CaO19.12072(MDH1) CaO19.12783(MDH3) CaO19.4602(MDH1)
                 CaO19.7481(MDH2)
            CTP: CTRG_00226 CTRG_01021 CTRG_02024
            CDU: CD36_24490 CD36_25650 CD36_41790
            YLI: YALI0D16753g YALI0E14190g
            CLU: CLUG_04330 CLUG_04354 CLUG_05128
            NCR: NCU04899 NCU06211
            PAN: PODANSg5466 PODANSg6062
            MGR: MGG_08835(MG08835.4) MGG_09367(MG09367.4)
            FGR: FG02461.1 FG02504.1
            SSL: SS1G_08975 SS1G_13825
            BFU: BC1G_07409 BC1G_10724
            ANI: AN6499.2 AN6717.2
            AFM: AFUA_6G05210 AFUA_7G05740
            NFI: NFIA_026980 NFIA_051790
            AOR: AO090005000438 AO090701000013
            ANG: An07g02160 An15g00070
            AFV: AFLA_054750 AFLA_076710
            ACT: ACLA_007430 ACLA_095320
            PCS: Pc12g04750 Pc20g01610
            CIM: CIMG_02580 CIMG_05466
            CPW: CPC735_037510 CPC735_066110
            URE: UREG_03159 UREG_06260
            PNO: SNOG_05974 SNOG_09027
            TML: GSTUM_00001731001 GSTUM_00005180001
            SPO: SPCC306.08c
            CNE: CNG03100 CNG03490
            CNB: CNBG1280 CNBG1650
            LBC: LACBIDRAFT_185536 LACBIDRAFT_326114
            MPR: MPER_07111
            CCI: CC1G_06656 CC1G_09115
            SCM: SCHCODRAFT_71301 SCHCODRAFT_85988
            UMA: UM00403.1
            MGL: MGL_2703 MGL_3809
            MBR: MONBRDRAFT_15806 MONBRDRAFT_38523
            DDI: DDB_G0280255(mdhC) DDB_G0290207(mdhA) DDB_G0292600(mdhB)
            EHI: EHI_030810(195.t00006) EHI_067860(8.t00059)
                 EHI_152670(24.t00003)
            EDI: EDI_082420 EDI_092900
            TET: TTHERM_00030190 TTHERM_00052260 TTHERM_00237500 TTHERM_01029960
            PTM: GSPATT00014396001 GSPATT00028542001 GSPATT00036328001
            TBR: Tb10.61.0980 Tb10.70.5110 Tb10.70.5120 Tb11.01.3040
            TCR: 506195.110 506503.69 506937.10 507883.100 507883.109 510437.40
                 511293.69
            LMA: LmjF19.0710 LmjF28.2860 LmjF34.0130 LmjF34.0140 LmjF34.0150
                 LmjF34.0160
            LIF: LinJ19.0540 LinJ28.3010 LinJ34.0140 LinJ34.0150 LinJ34.0160
                 LinJ34.0170
            LBZ: LbrM19_V2.1020 LbrM20_V2.0010 LbrM20_V2.0020 LbrM20_V2.0030
                 LbrM20_V2.0040 LbrM28_V2.3070
            GLA: GL50803_3331
            TVA: TVAG_171090 TVAG_171100 TVAG_193000 TVAG_204360 TVAG_354940
                 TVAG_381310 TVAG_534540
            PTI: PHATRDRAFT_51297(MDH)
            TPS: THAPSDRAFT_20726(MDH1) THAPS_41425
            PIF: PITG_13614
            ECO: b3236(mdh)
            ECJ: JW3205(mdh)
            ECD: ECDH10B_3413(mdh)
            EBW: BWG_2937(mdh)
            ECE: Z4595(mdh)
            ECS: ECs4109
            ECF: ECH74115_4553(mdh)
            ETW: ECSP_4205(mdh)
            EOJ: ECO26_4335(mdh)
            EOI: ECO111_4056(mdh)
            EOH: ECO103_3977(mdh)
            ECG: E2348C_3507(mdh)
            EOK: G2583_3956(mdh)
            ECC: c3991(mdh)
            ECP: ECP_3319
            ECI: UTI89_C3667(mdh)
            ECV: APECO1_3208(mdh)
            ECX: EcHS_A3425(mdh)
            ECW: EcE24377A_3719(mdh)
            ECM: EcSMS35_3532(mdh)
            ECY: ECSE_3515
            ECR: ECIAI1_3378(mdh)
            ECQ: ECED1_3886(mdh)
            ECK: EC55989_3649(mdh)
            ECT: ECIAI39_3727(mdh)
            EUM: ECUMN_3710(mdh)
            ECZ: ECS88_3612(mdh)
            ECL: EcolC_0470
            EBR: ECB_03096(mdh)
            EBD: ECBD_0511
            EFE: EFER_3213(mdh)
            STY: STY3539(mdh)
            STT: t3274(mdh)
            STM: STM3359(mdh)
            SPT: SPA3226(mdh)
            SEK: SSPA3012
            SPQ: SPAB_04185
            SEI: SPC_3429(mdh)
            SEC: SC3297(mdh)
            SEH: SeHA_C3657(mdh)
            SEE: SNSL254_A3622(mdh)
            SEW: SeSA_A3551(mdh)
            SEA: SeAg_B3550(mdh)
            SED: SeD_A3719(mdh)
            SEG: SG3249(mdh)
            SET: SEN3192(mdh)
            SES: SARI_04274
            YPE: YPO3516(mdh)
            YPK: y0668(mdh)
            YPA: YPA_0066
            YPN: YPN_3260
            YPM: YP_0567(mdh)
            YPP: YPDSF_3565
            YPG: YpAngola_A3971(mdh)
            YPZ: YPZ3_3246(mdh)
            YPS: YPTB0460(mdh)
            YPI: YpsIP31758_3616(mdh)
            YPY: YPK_3761
            YPB: YPTS_0490
            YEN: YE0414(mdh)
            SFL: SF3276(mdh)
            SFX: S3491(mdh)
            SFV: SFV_3263(mdh)
            SSN: SSON_3378(mdh)
            SBO: SBO_3153(mdh)
            SBC: SbBS512_E3540(mdh)
            SDY: SDY_3412(mdh)
            ECA: ECA0685(mdh)
            PCT: PC1_0553
            PWA: Pecwa_0788
            ETA: ETA_02980(mdh)
            EPY: EpC_03060(mdh)
            EAM: EAMY_0298(mdh)
            EAY: EAM_3121(mdh)
            EBI: EbC_40570(mdh)
            PLU: plu4547(mdh)
            PAY: PAU_04048(mdh)
            ENT: Ent638_3671
            ENC: ECL_04617
            ESC: Entcl_0474
            ESA: ESA_03622
            CTU: Ctu_03560(mdh)
            KPN: KPN_03644(mdh)
            KPE: KPK_0477(mdh)
            KPU: KP1_4960(mdh)
            KVA: Kvar_0455
            CKO: CKO_04641
            CRO: ROD_45871(mdh)
            SPE: Spro_0469
            PMR: PMI3400(mdh)
            EIC: NT01EI_0446
            ETR: ETAE_0386(mdh)
            HDE: HDEF_0460(mdh)
            DDA: Dd703_3365
            DDC: Dd586_0581
            DDD: Dda3937_03529(mdh)
            DZE: Dd1591_3484
            XBO: XBJ1_0349(mdh)
            XNE: XNC1_0485(mdh)
            PAM: PANA_3548(mdh)
            PVA: Pvag_2806(mdh)
            PAO: Pat9b_3569
            HIN: HI1210(mdh)
            HIT: NTHI1381(mdh)
            HIP: CGSHiEE_05985
            HIQ: CGSHiGG_09775
            HIF: HIBPF10540
            HIL: HICON_00870
            HDU: HD0264(mdh)
            HAP: HAPS_0981(mdh)
            HSO: HS_1055(mdh)
            HSM: HSM_1539
            PMU: PM0550(mdh_2)
            MSU: MS1266(mdh)
            APL: APL_1296(mdh)
            APJ: APJL_1309(mdh)
            APA: APP7_1347
            ASU: Asuc_1612
            AAP: NT05HA_1109
            AAT: D11S_1114
            XFA: XF1211
            XFT: PD0492(mdh)
            XFM: Xfasm12_0550
            XFN: XfasM23_0485
            XCC: XCC0928(mdh)
            XCB: XC_3307
            XCA: xccb100_3426(mdh)
            XCV: XCV1034(mdh)
            XAC: XAC1006(mdh)
            XOO: XOO0971(mdh)
            XOM: XOO_0886
            XOP: PXO_02545
            XAL: XALc_0546(mdh)
            SML: Smlt0944(mdh)
            SMT: Smal_0790
            PSU: Psesu_2303
            VCH: VC0432
            VCO: VC0395_A2850(mdh)
            VCM: VCM66_0417(mdh)
            VCJ: VCD_001175
            VVU: VV1_0673
            VVY: VV0467
            VVM: VVM_04251
            VPA: VP0325
            VHA: VIBHAR_00795
            VSP: VS_0358
            VEX: VEA_001676
            VFI: VF_0276(mdh)
            VFM: VFMJ11_0264(mdh)
            VSA: VSAL_I0359(mdh)
            PPR: PBPRA0391
            PPU: PP_0654(mdh)
            PPF: Pput_0687
            PPG: PputGB1_0697
            PEN: PSEEN2621(mdh)
            CJA: CJA_1983(mdh)
            PAR: Psyc_1763(mdh)
            PCR: Pcryo_2044
            PRW: PsycPRwf_1873
            ACI: ACIAD3155(mdh)
            ACD: AOLE_02365
            ACB: A1S_3025
            ABM: ABSDF0482(mdh)
            ABY: ABAYE0465(mdh)
            ABC: ACICU_03222
            ABN: AB57_3474
            ABB: ABBFA_000492
            MCT: MCR_1446(mdh)
            SON: SO_0770(mdh)
            SDN: Sden_0826
            SFR: Sfri_3173
            SAZ: Sama_0672
            SBL: Sbal_0609
            SBM: Shew185_3685
            SBN: Sbal195_3809
            SBP: Sbal223_3627
            SLO: Shew_0867
            SPC: Sputcn32_3219
            SSE: Ssed_0952
            SPL: Spea_0850
            SHE: Shewmr4_3339
            SHM: Shewmr7_0614
            SHN: Shewana3_3509
            SHW: Sputw3181_0722
            SHL: Shal_0903
            SWD: Swoo_1002
            SWP: swp_4100
            SVO: SVI_0784(mdh)
            ILO: IL0472(mdh)
            CPS: CPS_4514(mdh)
            PHA: PSHAa2658(mdh)
            PAT: Patl_0539
            PSM: PSM_A2695(mdh)
            SDE: Sde_1659
            AMC: MADE_00736
            PIN: Ping_0297
            TTU: TERTU_1732
            FBL: Fbal_3374
            CBU: CBU_1241(mdh)
            CBS: COXBURSA331_A1384(mdh)
            CBD: CBUD_1325(mdh)
            CBG: CbuG_0769(mdh)
            CBC: CbuK_1102(mdh)
            LPN: lpg2352(mdh)
            LPF: lpl2274(mdh)
            LPP: lpp2301(mdh)
            LPC: LPC_1821(mdh)
            LPA: lpa_03369(mdh)
            LLO: LLO_2851(mdh)
            MCA: MCA0610(mdh)
            FTU: FTT_0535c(mdh)
            FTF: FTF0535c(mdh)
            FTW: FTW_1007(mdh)
            FTL: FTL_0987
            FTH: FTH_0966(mdh)
            FTA: FTA_1040(mdh)
            FTM: FTM_1149(mdh)
            FTN: FTN_0980(mdh)
            FPH: Fphi_1620
            NOC: Noc_2802
            NHL: Nhal_0324
            NWA: Nwat_0286
            AEH: Mlg_0487
            HHA: Hhal_0830
            TGR: Tgr7_2971
            TKM: TK90_2377
            HCH: HCH_01978(mdh)
            HEL: HELO_1693(mdh)
            ABO: ABO_1248(mdh)
            KKO: Kkor_2420
            AHA: AHA_0659(mdh)
            ASA: ASA_0659(mdh)
            TAU: Tola_2549
            AFE: Lferr_2610
            AFR: AFE_3000
            GPB: HDN1F_34290
            CVI: CV_1062(mdh)
            LHK: LHK_02423(mdh)
            RSO: RSc1998(mdh)
            RSC: RCFBP_11387(mdh)
            RSL: RPSI07_1431(mdh)
            RPI: Rpic_2153
            RPF: Rpic12D_1829
            REU: Reut_A2327
            REH: H16_A2634(mdh1)
            RME: Rmet_2489
            CTI: RALTA_A2133(mdh)
            BMA: BMAA1751(mdh)
            BMV: BMASAVP1_1619(mdh)
            BML: BMA10229_1827(mdh)
            BMN: BMA10247_A0497(mdh)
            BPS: BPSS1722(mdh)
            BPM: BURPS1710b_A0795(mdh)
            BPL: BURPS1106A_A2336
            BPD: BURPS668_A2474
            BTE: BTH_II0658 BTH_II1617
            BVI: Bcep1808_3766 Bcep1808_4408
            BUR: Bcep18194_B2154
            BCN: Bcen_4435
            BCH: Bcen2424_3932
            BCM: Bcenmc03_3596
            BCJ: BCAM0965(mdh)
            BAM: Bamb_3309
            BAC: BamMC406_3825 BamMC406_4642
            BMU: Bmul_4651
            BMJ: BMULJ_03862(mdh)
            BXE: Bxe_B2898
            BPH: Bphy_4358
            BPY: Bphyt_6858
            BGL: bglu_2g08210
            BGE: BC1002_5195
            BRH: RBRH_00167
            PNU: Pnuc_0756
            PNE: Pnec_1065
            BPE: BP2365(mdh)
            BPA: BPP3232(mdh)
            BBR: BB3684(mdh)
            BPT: Bpet1818(mdh1)
            BAV: BAV1180(mdh)
            AXY: AXYL_01627
            TEQ: TEQUI_1590
            RFR: Rfer_1803 Rfer_2403
            POL: Bpro_3598
            PNA: Pnap_3030
            AAV: Aave_2206
            AJS: Ajs_2791
            DIA: Dtpsy_2281
            VEI: Veis_4356
            DAC: Daci_2429
            VAP: Vapar_1432
            VPE: Varpa_1576
            CTT: CtCNB1_3388
            ADN: Alide_1963
            MPT: Mpe_A2172 Mpe_B0497
            HAR: HEAR1780(mdh)
            MMS: mma_1504(mdh)
            HSE: Hsero_2976(mdh)
            LCH: Lcho_2708
            TIN: Tint_2342
            NEU: NE0773
            NET: Neut_1633
            NMU: Nmul_A0864
            EBA: ebA6695(mdh)
            AZO: azo1547(mdh)
            DAR: Daro_2867
            TMZ: Tmz1t_2552
            APP: CAP2UW1_1299 CAP2UW1_2380
            SLT: Slit_1842
            GCA: Galf_1330
            HHE: HH1571(mdh)
            WSU: WS1064(citH)
            TDN: Suden_1048
            SKU: Sulku_1463
            CJE: Cj0532(mdh)
            CJR: CJE0636(mdh)
            CJJ: CJJ81176_0557(mdh)
            CJU: C8J_0493(mdh)
            CJN: ICDCCJ_479
            CJD: JJD26997_1398(mdh)
            CFF: CFF8240_0912
            CCV: CCV52592_1883
            CHA: CHAB381_1136
            CCO: CCC13826_2254
            CLA: Cla_0818(mdh)
            ABU: Abu_1315(mdh)
            ANT: Arnit_1922
            SDL: Sdel_1088
            NIS: NIS_0835(mdh)
            SUN: SUN_0571 SUN_0572
            NSA: Nitsa_0356
            NAM: NAMH_1234(mdh)
            GSU: GSU1466(mdh)
            GME: Gmet_1360
            GUR: Gura_2193
            GLO: Glov_1625
            GBM: Gbem_2900(mdh)
            GEO: Geob_2664
            GEM: GM21_1325
            PCA: Pcar_1037(mdh)
            PPD: Ppro_2327
            BBA: Bd0928(mdh)
            DPS: DP0661
            DAK: DaAHT2_0941
            DPR: Despr_2759
            DOL: Dole_2374
            DAL: Dalk_0818
            ADE: Adeh_1626 Adeh_2226
            ACP: A2cp1_1722 A2cp1_2322
            AFW: Anae109_1589 Anae109_2185
            ANK: AnaeK_1649 AnaeK_2234
            MXA: MXAN_3538(mdh)
            SCL: sce1050(mdh)
            HOH: Hoch_4268
            SFU: Sfum_0460
            DBR: Deba_1366
            RPR: RP376
            RTY: RT0365(mdh)
            RCM: A1E_03540
            RCO: RC0520(mdh)
            RFE: RF_0590(mdh)
            RAK: A1C_02825
            RRI: A1G_02950
            RRJ: RrIowa_0618
            RMS: RMA_0536(mdh)
            RPK: RPR_05955
            RAF: RAF_ORF0481(mdh)
            RBE: RBE_0644(mdh)
            RBO: A1I_04320
            OTS: OTBS_1845(mdh)
            OTT: OTT_1326(mdh)
            WOL: WD1121(mdh)
            WBM: Wbm0244
            WRI: WRi_012940(mdh)
            WPI: WPa_0855(mdh)
            AMA: AM564(mdh)
            AMF: AMF_421(mdh)
            ACN: ACIS_00745(mdh)
            APH: APH_0629(mdh)
            ERU: Erum4090(mdh)
            ERW: ERWE_CDS_04240(mdh)
            ERG: ERGA_CDS_04180(mdh)
            ECN: Ecaj_0398
            ECH: ECH_0641(mdh)
            NSE: NSE_0956(mdh)
            NRI: NRI_0913
            PUB: SAR11_0240(mdh)
            MLO: mll4308
            MCI: Mesci_0987
            MES: Meso_3395
            PLA: Plav_1450
            SME: SMc02479(mdh)
            SMD: Smed_2944
            RHI: NGR_c31300
            ATU: Atu2639
            ARA: Arad_4338(mdh)
            AVI: Avi_4129(mdh)
            RET: RHE_CH03891(mdh)
            REC: RHECIAT_CH0004174(mdh)
            RLE: RL4439(mdh)
            RLT: Rleg2_3685
            RLG: Rleg_3974
            LAS: CLIBASIA_04750(mdh)
            LSO: CKC_03190
            BME: BMEI0137
            BMI: BMEA_A1984(mdh)
            BMF: BAB1_1927(mdh)
            BMB: BruAb1_1903(mdh)
            BMC: BAbS19_I18080
            BMS: BR1927(mdh)
            BMT: BSUIS_A1767(mdh)
            BOV: BOV_1856(mdh)
            BCS: BCAN_A1971(mdh)
            BMR: BMI_I1949(mdh)
            OAN: Oant_0930
            BJA: bll0456(mdh)
            BRA: BRADO0403(mdh)
            BBT: BBta_0392(mdh)
            RPA: RPA0192(mdh)
            RPB: RPB_0281
            RPC: RPC_0194 RPC_4584
            RPD: RPD_0535
            RPE: RPE_0300
            RPT: Rpal_0187
            RPX: Rpdx1_0446
            NWI: Nwi_0419
            NHA: Nham_0545
            OCA: OCAR_4581
            BHE: BH16570(mdh)
            BQU: BQ13450(mdh)
            BBK: BARBAKC583_0022(mdh)
            BTR: Btr_2679(mdh)
            BGR: Bgr_20150(mdh)
            BCD: BARCL_1381(mdh)
            XAU: Xaut_0153 Xaut_0258 Xaut_1673
            AZC: AZC_4016 AZC_4186
            SNO: Snov_3299
            MEX: Mext_1643
            MEA: Mex_1p1537(mdh)
            MDI: METDI2311(mdh)
            MRD: Mrad2831_0919
            MET: M446_2161
            MPO: Mpop_1587
            MCH: Mchl_1925
            MNO: Mnod_1123
            BID: Bind_3604
            MSL: Msil_2501
            HDN: Hden_3231
            RVA: Rvan_0646
            CCR: CC_3655
            CCS: CCNA_03770
            CAK: Caul_5004
            CSE: Cseg_4147
            PZU: PHZ_c0152(mdh)
            BSB: Bresu_0442
            AEX: Astex_0205
            SIL: SPO0349(mdh)
            SIT: TM1040_3517
            RSP: RSP_0968(mdh)
            RSH: Rsph17029_2628
            RSQ: Rsph17025_0080
            RSK: RSKD131_2360
            RCP: RCAP_rcc00718(mdh)
            JAN: Jann_0818
            RDE: RD1_1617(mdh)
            PDE: Pden_0561
            DSH: Dshi_2876(mdh)
            KVU: EIO_0118
            MMR: Mmar10_2829
            HNE: HNE_3218(mdh)
            HBA: Hbal_2253
            NAR: Saro_1182
            SAL: Sala_2230
            SWI: Swit_1300
            SJP: SJA_C1-24340(mdh)
            ELI: ELI_07980
            GBE: GbCGDNIH1_2071
            ACR: Acry_3063
            RRU: Rru_A1210
            RCE: RC1_4080(mdh)
            MAG: amb3957
            AZL: AZL_025750(mdh)
            PBR: PB2503_01232
            APB: SAR116_1831
            MGM: Mmc1_0813
            DIN: Selin_2133
            BSU: BSU29120(mdh)
            BSS: BSUW23_14155(mdh)
            BHA: BH3158(citH)
            BAN: BA_4837(mdh)
            BAR: GBAA_4837(mdh)
            BAT: BAS4486
            BAH: BAMEG_4868(mdh)
            BAI: BAA_4848(mdh)
            BAL: BACI_c45840(mdh1)
            BCE: BC4592
            BCA: BCE_4723(mdh)
            BCZ: BCZK4333(mdh)
            BCR: BCAH187_A4718(mdh)
            BCB: BCB4264_A4702(mdh)
            BCU: BCAH820_4707(mdh)
            BCG: BCG9842_B0536(mdh)
            BCQ: BCQ_4396(mdh)
            BCX: BCA_4702(mdh)
            BCY: Bcer98_3276
            BTK: BT9727_4321(mdh)
            BTL: BALH_4176(mdh)
            BTB: BMB171_C4235(mdh)
            BWE: BcerKBAB4_4422
            BLI: BL00397(mdh)
            BLD: BLi03060(mdh)
            BAY: RBAM_026160(mdh)
            BAO: BAMF_2715(mdh)
            BAE: BATR1942_12345
            BCL: ABC2713(mdh)
            BPU: BPUM_2554(mdh)
            BPF: BpOF4_03355(mdhA)
            BMQ: BMQ_3673(mdh) BMQ_4768(mdh)
            BMD: BMD_3656(mdh) BMD_4754(mdh)
            BSE: Bsel_1355
            BCO: Bcell_3218
            OIH: OB2166(citH)
            GKA: GK2734
            GTN: GTNG_2658
            GWC: GWCH70_2677
            GYM: GYMC10_4926
            GYC: GYMC61_0783
            GYA: GYMC52_2769
            GCT: GC56T3_0759
            GMC: GY4MC1_0835
            AFL: Aflv_0506(mdh)
            SEP: SE0461
            SER: SERP0347(mdh)
            SSP: SSP2027
            SCA: Sca_0338(mdh)
            SLG: SLGD_02139
            SSD: SPSINT_0402
            LMN: LM5578_1679
            LMY: LM5923_1631
            LSP: Bsph_2109 Bsph_4120
            ESI: Exig_2207
            EAT: EAT1b_0665
            MCL: MCCL_1360
            BBE: BBR47_13910(mdh) BBR47_56130(mdh)
            PJD: Pjdr2_4471
            PPY: PPE_01588
            PPM: PPSC2_c1757
            AAC: Aaci_2347
            BTS: Btus_2428
            SGA: GALLO_1129(ldhA)
            STH: STH2543
            DSY: DSY3584
            DHD: Dhaf_1799
            DRM: Dred_1867
            PTH: PTH_1367(mmcK)
            DAU: Daud_1121
            HMO: HM1_1472(mdh)
            TMR: Tmar_1268
            MTU: Rv1240(mdh)
            MTC: MT1278(mdh)
            MRA: MRA_1249(mdh)
            MTF: TBFG_11265
            MTB: TBMG_02741(TBMG_02741.1)
            MBO: Mb1272(mdh)
            MBB: BCG_1300(mdh)
            MBT: JTY_1275(mdh)
            MLE: ML1091(mdh)
            MLB: MLBr_01091(mdh)
            MPA: MAP2541c(mdh)
            MAV: MAV_1380
            MUL: MUL_4504(mdh)
            MVA: Mvan_3067
            MGI: Mflv_3339
            MSP: Mspyr1_26700
            MMI: MMAR_4198(mdh)
            CGL: NCgl2297(cgl2380)
            CGB: cg2613(mdh)
            CGT: cgR_2262
            CEF: CE2285(mdh)
            CDI: DIP1787(mdh)
            CJK: jk0548(mdh)
            CUR: cur_1376
            CAR: cauri_1878(mdh)
            CKP: ckrop_1368(mdh)
            CPU: cpfrc_01600(mdh)
            NFA: nfa36620(mdh)
            RHA: RHA1_ro06244(mdh)
            RER: RER_29370(mdh)
            ROP: ROP_63030(mdh)
            REQ: REQ_21010
            GBR: Gbro_2783
            SRT: Srot_0534
            SCO: SCO4827(mdh)
            SMA: SAV_3436(mdh)
            SGR: SGR_2711
            SCB: SCAB_35681(mdh)
            AAU: AAur_0570(mdh)
            KRH: KRH_08010(mdh)
            MLU: Mlut_00950
            RMU: RMDY18_10640
            BCV: Bcav_3006
            JDE: Jden_0688
            KSE: Ksed_07840
            XCE: Xcel_0743
            SKE: Sked_28070
            CFL: Cfla_2522
            ICA: Intca_1119
            PAC: PPA1740
            PAK: HMPREF0675_4794
            PFR: PFREUD_06860(mdh)
            NCA: Noca_3578
            KFL: Kfla_1287
            TFU: Tfu_0092
            NDA: Ndas_0774
            TCU: Tcur_4209
            SRO: Sros_1259
            FRA: Francci3_3441
            FRE: Franean1_5970
            FRI: FraEuI1c_4622
            FAL: FRAAL5612(mdh)
            ACE: Acel_0387
            NML: Namu_2256 Namu_2341
            GOB: Gobs_4414
            SEN: SACE_3674(mdh)
            SVI: Svir_19950
            TBI: Tbis_2659
            AMD: AMED_4640(mdh)
            AMI: Amir_6492
            STP: Strop_3794
            SAQ: Sare_4174
            MAU: Micau_5383
            MIL: ML5_0476
            CAI: Caci_7973
            SNA: Snas_0615
            AHE: Arch_1287
            MCU: HMPREF0573_10269(mdh)
            BDE: BDP_1558(ldh2)
            GVA: HMPREF0424_0584
            RXY: Rxyl_1290
            CWO: Cwoe_5280
            AFO: Afer_1880
            ELE: Elen_1140
            CTR: CT376(mdhC)
            CTA: CTA_0410(mdhC)
            CTB: CTL0630(mdhC)
            CTL: CTLon_0628(mdhC)
            CTJ: JALI_3741(mdhC)
            CTZ: CTB_3741(mdhC)
            CMU: TC0655(mdh)
            CPN: CPn1028(mdhC)
            CPA: CP0824
            CPJ: CPj1028(mdhC)
            CPT: CpB1067
            CCA: CCA00734(mdh)
            CAB: CAB701
            CFE: CF0282(mdhC)
            PCU: pc1772(mdh)
            LIL: LA_2139(mdh)
            LIC: LIC11781(mdh)
            LBJ: LBJ_1874(mdh)
            LBL: LBL_1410(mdh)
            LBI: LEPBI_I1144(mdh)
            LBF: LBF_1102(mdh)
            ABA: Acid345_1951
            ACA: ACP_0090(mdh)
            SUS: Acid_1549
            BTH: BT_2510 BT_3911
            BFR: BF0541 BF3978
            BFS: BF0489 BF3753(mdh)
            BVU: BVU_0256 BVU_0462
            BHL: Bache_0106 Bache_0270
            PGI: PG1949(mdh)
            PGN: PGN_1880
            PDI: BDI_0389 BDI_0711
            PPN: Palpr_2611
            APS: CFPG_305
            PRU: PRU_2158
            PMZ: HMPREF0659_A5283
            SRU: SRU_1571(mdh)
            SRM: SRM_01768(mdh)
            RMR: Rmar_0912
            CHU: CHU_3020(mdh)
            DFE: Dfer_4459
            SLI: Slin_4496
            LBY: Lbys_1576
            MTT: Ftrac_0965
            CPI: Cpin_1656
            PHE: Phep_0864
            GFO: GFO_2747(mdh)
            FJO: Fjoh_2255
            FPS: FP0528(mdh)
            COC: Coch_1689
            RBI: RB2501_10467
            ZPR: ZPR_3792
            CAT: CA2559_08746
            RAN: Riean_0627
            FBC: FB2170_01791
            CAO: Celal_0509
            FBA: FIC_02092
            BBL: BLBBGE_617(mdh)
            BPI: BPLAN_024(mdh)
            FSU: Fisuc_2615
            OTE: Oter_0511
            CAA: Caka_2804
            MIN: Minf_1373(mdh)
            AMU: Amuc_1436
            GAU: GAU_1670(mdh)
            RBA: RB7652(mdh)
            PSL: Psta_4330
            PLM: Plim_1133
            IPA: Isop_3050
            SYN: sll0891(citH)
            SYP: SYNPCC7002_A2093(mdh)
            MAR: MAE_09540
            CYT: cce_1850(mdh)
            CYP: PCC8801_0522
            CYC: PCC7424_2178
            CYH: Cyan8802_0539
            CYJ: Cyan7822_3004
            GVI: gll2542
            ANA: alr4322
            NPU: Npun_R3934
            AVA: Ava_1273
            AMR: AM1_2135(mdh)
            CTE: CT1507(mdh)
            CPC: Cpar_1594
            CCH: Cag_0862
            CPH: Cpha266_1900
            CPB: Cphamn1_0832
            CLI: Clim_1713
            PVI: Cvib_1331
            PLT: Plut_1510
            PPH: Ppha_1029
            PAA: Paes_1603
            CTS: Ctha_0098
            DET: DET0451(mdh)
            DEH: cbdb_A409(mdh)
            DEB: DehaBAV1_0428
            DEV: DhcVS_393(mdh)
            DEG: DehalGT_0392
            DLY: Dehly_0359
            RRS: RoseRS_0253
            RCA: Rcas_0283
            CAU: Caur_0900
            CAG: Cagg_2290
            CHL: Chy400_0980
            HAU: Haur_4206
            TRO: trd_0921(mdh)
            STI: Sthe_1112
            DRA: DR_0325
            DGE: Dgeo_2161
            DDR: Deide_20240(mdh)
            DMR: Deima_0786
            TRA: Trad_2990
            TTH: TTC0168
            TTJ: TTHA0536
            TSC: TSC_c07070(mdh)
            MRB: Mrub_0978
            MSV: Mesil_1713
            OPR: Ocepr_1164
            AAE: aq_1665(mdh2) aq_1782(mdh1)
            HYA: HY04AAS1_0605
            HTH: HTH_0756(mdh)
            TAL: Thal_0684
            SUL: SYO3AOP1_0624
            SAF: SULAZ_0634
            PMX: PERMA_1130
            TAM: Theam_0602
            TYE: THEYE_A1587(mdh1)
            NDE: NIDE3562(mdh)
            DDF: DEFDS_0919(mdh)
            DAP: Dacet_2346
            CNI: Calni_0463
            MJA: MJ_0490
            MFE: Mefer_0722
            MVU: Metvu_0361
            MFS: MFS40622_1761
            MIF: Metin_1004
            MMP: MMP0645(mdh)
            MMQ: MmarC5_0959
            MMX: MmarC6_0244
            MMZ: MmarC7_1669
            MAE: Maeo_0610
            MVN: Mevan_1548
            MVO: Mvol_0901
            MAC: MA0819
            MBA: Mbar_A1748
            MMA: MM_1966
            MMH: Mmah_1107
            MEV: Metev_1117
            MHU: Mhun_1155 Mhun_2343
            MLA: Mlab_0615 Mlab_1271
            MEM: Memar_0797 Memar_2444
            MPI: Mpet_0162 Mpet_1928
            MBN: Mboo_0492 Mboo_1109
            MPL: Mpal_1741 Mpal_2590
            MTH: MTH188
            MMG: MTBMA_c06400(mdh)
            MST: Msp_0672
            MRU: mru_1255(mdh)
            MKA: MK1069(ldh)
            AFU: AF0855(mdhA)
            APO: Arcpr_0622
            FPL: Ferp_2001
            HAL: VNG2367G(mdhA)
            HSL: OE4323F(mdhA)
            HMA: rrnAC2706(mdh)
            HWA: HQ3459A(mdhA)
            NPH: NP0498A(mdhA)
            HLA: Hlac_2649
            HMU: Hmuk_0803
            HTU: Htur_3728
            NMG: Nmag_1974
            HVO: HVO_3007(mdhA)
            HBO: Hbor_02300
            TAC: Ta0952
            TVO: TVN1097
            PTO: PTO0994
            TSI: TSIB_1633
            APE: APE_0672.1(mdh)
            IHO: Igni_1263
            SSO: SSO2585(sqdB)
            STO: ST1811
            SAI: Saci_0246
            SIS: LS215_2892
            SIA: M1425_2725
            SIM: M1627_2779
            SID: M164_2710
            SIY: YG5714_2905
            SIN: YN1551_3092
            SII: LD85_3051
            MSE: Msed_0455
            PAI: PAE2370
            PIS: Pisl_0612
            PCL: Pcal_1699
            PAS: Pars_1571
            CMA: Cmaq_1675
            TNE: Tneu_1509
            VDI: Vdis_1757
            ASC: ASAC_0288
            NMR: Nmar_0338
            CSY: CENSYa_1575
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.37
            IUBMB Enzyme Nomenclature: 1.1.1.37
            ExPASy - ENZYME nomenclature database: 1.1.1.37
            BRENDA, the Enzyme Database: 1.1.1.37
            CAS: 9001-64-3
///
ENTRY       EC 1.1.1.38                 Enzyme
NAME        malate dehydrogenase (oxaloacetate-decarboxylating);
            'malic' enzyme;
            pyruvic-malic carboxylase;
            NAD+-specific malic enzyme;
            NAD+-malic enzyme;
            NAD+-linked malic enzyme
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)
REACTION    (S)-malate + NAD+ = pyruvate + CO2 + NADH [RN:R00214]
ALL_REAC    R00214;
            (other) R00217
SUBSTRATE   (S)-malate [CPD:C00149];
            NAD+ [CPD:C00003]
PRODUCT     pyruvate [CPD:C00022];
            CO2 [CPD:C00011];
            NADH [CPD:C00004]
COMMENT     Also decarboxylates added oxaloacetate.
REFERENCE   1  [PMID:14917678]
  AUTHORS   KAUFMAN S, KORKES S, DEL CAMPILLO A.
  TITLE     Biosynthesis of dicarboxylic acids by carbon dioxide fixation. V.
            Further study of the "malic" enzyme of Lactobacillus arabinosus.
  JOURNAL   J. Biol. Chem. 192 (1951) 301-12.
  ORGANISM  Lactobacillus arabinosus
PATHWAY     ec00620  Pyruvate metabolism
ORTHOLOGY   K00027  malate dehydrogenase (oxaloacetate-decarboxylating)
GENES       HSA: 4200(ME2)
            PTR: 455422(ME2)
            PON: 100440529(ME2)
            MCC: 711129(ME2)
            MMU: 107029(Me2)
            RNO: 307270(Me2)
            CFA: 476198(ME2)
            AML: 100465573(ME2)
            BTA: 507817(ME2)
            SSC: 100524659(ME2)
            ECB: 100069637
            MDO: 100010878(ME2)
            OAA: 100078022
            TGU: 100221226
            XLA: 398584(me2)
            XTR: 548395(me2)
            DRE: 445233(me2)
            SCE: YKL029C(MAE1)
            AGO: AGOS_AGL068W
            KLA: KLLA0E18635g
            LTH: KLTH0D06732g
            PPA: PAS_chr3_0181
            VPO: Kpol_1018p36 Kpol_348p7
            ZRO: ZYRO0B01914g
            CGR: CAGL0L02035g
            DHA: DEHA2F12012g
            PIC: PICST_89732(MAE1)
            PGU: PGUG_00881
            LEL: LELG_04771
            CAL: CaO19.10923(MAE1)
            CTP: CTRG_02875
            CDU: CD36_61770
            YLI: YALI0E18634g
            CLU: CLUG_05483
            NCR: NCU02906
            PAN: PODANSg09257
            MGR: MGG_08562(MG08562.4)
            FGR: FG00805.1
            SSL: SS1G_12079
            BFU: BC1G_13155
            ANI: AN6933.2
            AFM: AFUA_7G02420
            NFI: NFIA_115160
            AOR: AO090038000621
            ANG: An12g00160
            AFV: AFLA_071570
            ACT: ACLA_065100
            PCS: Pc21g20250
            PNO: SNOG_09809
            TML: GSTUM_00004787001
            SPO: SPCC794.12c(mae2)
            CNE: CNF03780
            CNB: CNBF1040 CNBH2110
            PPL: POSPLDRAFT_89079
            LBC: LACBIDRAFT_240874 LACBIDRAFT_255095
            SCM: SCHCODRAFT_62284 SCHCODRAFT_74986
            EHI: EHI_044970(425.t00002)
            EDI: EDI_245690
            TET: TTHERM_00569410
            PTM: GSPATT00016144001
            TBR: Tb11.02.3120 Tb11.02.3130
            TCR: 505183.20 505183.30 508647.270 508647.280
            LMA: LmjF24.0770
            LIF: LinJ24.0420 LinJ24.0430
            LBZ: LbrM24_V2.0780 LbrM24_V2.0790
            TVA: TVAG_009460 TVAG_241160 TVAG_412220
            ECO: b1479(maeA)
            ECJ: JW5238(sfcA)
            ECD: ECDH10B_1610(maeA)
            EBW: BWG_1300(maeA)
            ECE: Z2231(sfcA)
            ECS: ECs2083
            ECF: ECH74115_2091(sfcA)
            ETW: ECSP_1963(sfcA)
            EOJ: ECO26_2077(sfcA)
            EOI: ECO111_1869(sfcA)
            EOH: ECO103_1608(sfcA)
            ECG: E2348C_1613(maeA)
            EOK: G2583_1842(maeA)
            ECC: c1912(sfcA)
            ECP: ECP_1481
            ECI: UTI89_C1697(sfcA)
            ECV: APECO1_615(sfcA)
            ECX: EcHS_A1564(sfcA)
            ECW: EcE24377A_1661(sfcA)
            ECM: EcSMS35_1695(sfcA)
            ECY: ECSE_1568
            ECR: ECIAI1_1483(sfcA)
            ECQ: ECED1_1632(sfcA)
            ECK: EC55989_1611(sfcA)
            ECT: ECIAI39_1743(sfcA)
            EUM: ECUMN_1734(sfcA)
            ECZ: ECS88_1573(sfcA)
            ECL: EcolC_2178
            EBR: ECB_01437(sfcA)
            EBD: ECBD_2160
            EFE: EFER_1496(sfcA)
            STY: STY1494(sfcA)
            STT: t1481(sfcA)
            STM: STM1566(sfcA)
            SPT: SPA1302(sfcA)
            SEK: SSPA1210
            SPQ: SPAB_01733
            SEI: SPC_2172(sfcA)
            SEC: SC1567(sfcA)
            SEH: SeHA_C1743
            SEE: SNSL254_A1680
            SEW: SeSA_A1682
            SEA: SeAg_B1599
            SED: SeD_A1777
            SEG: SG1561(sfcA)
            SET: SEN1489(sfcA)
            SES: SARI_01403
            YPE: YPO1511(sfcA)
            YPK: y2658(sfcA)
            YPA: YPA_0806
            YPN: YPN_2468
            YPM: YP_1401(sfcA1)
            YPP: YPDSF_1463
            YPZ: YPZ3_1378(sfcA)
            YPS: YPTB1526(sfcA)
            YPI: YpsIP31758_2463
            YPY: YPK_2562
            YPB: YPTS_1636
            YEN: YE2794(maeA)
            SFL: SF1746(sfcA)
            SFX: S1879(sfcA)
            SFV: SFV_1742(sfcA)
            SSN: SSON_1645(sfcA)
            SBO: SBO_1578(sfcA)
            SBC: SbBS512_E1742(sfcA)
            ECA: ECA2831(sfcA)
            PCT: PC1_1494
            PWA: Pecwa_2971
            ETA: ETA_12950(sfcA)
            EPY: EpC_13570(sfcA)
            EAM: EAMY_2284(sfcA)
            EAY: EAM_2203(sfcA)
            EBI: EbC_29780(sfcA)
            PLU: plu1546(maeA)
            PAY: PAU_02896(sfcA)
            SGL: SG0967
            ENT: Ent638_2047
            ENC: ECL_01882 ECL_01910
            ESC: Entcl_1687 Entcl_2342
            ESA: ESA_02975
            CTU: Ctu_08890(sfcA)
            KPN: KPN_01847(sfcA)
            KPE: KPK_1916 KPK_2508(sfcA)
            KPU: KP1_2910(sfcA)
            KVA: Kvar_1737 Kvar_2456
            CKO: CKO_01517
            CRO: ROD_15561(sfcA)
            SPE: Spro_1567
            PMR: PMI0642(sfcA)
            EIC: NT01EI_1281
            ETR: ETAE_1161
            HDE: HDEF_1806(sfcA)
            DDA: Dd703_2451
            DDC: Dd586_2497
            DDD: Dda3937_03741(sfcA)
            DZE: Dd1591_2546
            XBO: XBJ1_0940(sfcA)
            XNE: XNC1_1492(sfcA)
            PAM: PANA_2537(sfcA)
            PVA: Pvag_2021(sfcA)
            PAO: Pat9b_2634
            AAT: D11S_1980
            VCH: VC1188
            VCO: VC0395_A0809(sfcA)
            VCM: VCM66_1143(sfcA)
            VCJ: VCD_003155
            VVU: VV1_2801
            VVY: VV1464 VV2242
            VVM: VVM_03336
            VPA: VP1258
            VHA: VIBHAR_02034
            VSP: VS_1202
            VEX: VEA_003737
            VFI: VF_1558(maeA)
            VFM: VFMJ11_1654
            VSA: VSAL_I1274(sfcA)
            PPR: PBPRA1997 PBPRB1354
            PAE: PA3471
            PAU: PA14_19190(sfcA)
            PAP: PSPA7_1656
            PAG: PLES_15411
            PST: PSPTO_3924(sfcA)
            PSB: Psyr_1561
            PSP: PSPPH_1545
            CJA: CJA_1688(sfcA1)
            PAR: Psyc_1387
            PCR: Pcryo_0982
            ACI: ACIAD0166(sfcA)
            ACD: AOLE_18640
            ACB: A1S_0140
            ABY: ABAYE3731(sfcA)
            ABC: ACICU_00164
            ABN: AB57_0179
            ABB: ABBFA_003379(sfcA)
            SON: SO_3855(sfcA)
            SDN: Sden_0736
            SFR: Sfri_0833
            SAZ: Sama_2621
            SBL: Sbal_0676
            SBM: Shew185_3634
            SBN: Sbal195_3757
            SBP: Sbal223_3566
            SLO: Shew_2962
            SPC: Sputcn32_0784
            SSE: Ssed_3518
            SPL: Spea_3186
            SHE: Shewmr4_3188
            SHM: Shewmr7_0778
            SHN: Shewana3_0750
            SHW: Sputw3181_3391
            SHL: Shal_3267
            SWD: Swoo_0902
            SWP: swp_3875
            SVO: SVI_3447(sfcA)
            ILO: IL0598(sfcA)
            CPS: CPS_4262(sfcA)
            PHA: PSHAa1565(sfcA)
            PAT: Patl_0724
            PSM: PSM_A1540(sfcA)
            AMC: MADE_00517
            PIN: Ping_0537
            FBL: Fbal_1754
            CBU: CBU_0823(sfcA)
            CBS: COXBURSA331_A1127(sfcA)
            CBD: CBUD_0888(sfcA)
            CBG: CbuG_1178(sfcA)
            CBC: CbuK_0691(sfcA)
            LPN: lpg0651 lpg1280(sfcA) lpg2971(maeA)
            LPF: lpl1243(sfcA) lpl2901
            LPP: lpp1243(sfcA) lpp3043
            LPC: LPC_0705(sfcA) LPC_3286(maeA)
            LPA: lpa_01911 lpa_04355
            LLO: LLO_0429(sfcA) LLO_0659 LLO_1147(sfcA)
            MCA: MCA1836(sfcA)
            FTU: FTT_0917(maeA)
            FTF: FTF0917(maeA)
            FTW: FTW_1262
            FTL: FTL_0438
            FTH: FTH_0430(maeA)
            FTA: FTA_0460
            FTM: FTM_0505(maeA)
            FTN: FTN_0443(maeA)
            FPH: Fphi_0394
            CSA: Csal_2963
            HEL: HELO_3817(sfcA)
            KKO: Kkor_2441
            AHA: AHA_1243 AHA_1278 AHA_3059
            ASA: ASA_1233(sfcA) ASA_1264(maeA)
            TAU: Tola_0213
            RMA: Rmag_0819
            NMA: NMA0870
            NME: NMB0671(sfcA)
            NMC: NMC0620(maeA)
            NMN: NMCC_0624(maeA)
            NGO: NGO0240
            BPD: BURPS668_0794
            HHE: HH1094
            CJE: Cj1287c
            ABU: Abu_1076(maeA)
            GSU: GSU2308(scfA)
            DDS: Ddes_1534
            BBA: Bd2834(sfcA)
            DPS: DP2203
            DAK: DaAHT2_0492
            DAT: HRM2_13730(mae)
            SCL: sce5603(maeB1)
            SAT: SYN_00517
            MET: M446_1242
            ZMO: ZMO1955
            ZMN: Za10_1214
            GBE: GbCGDNIH1_2016
            BSU: BSU23550(mleA) BSU29220(ytsJ) BSU29880(malS) BSU37050(ywkA)
            BSS: BSUW23_11570(mleA) BSUW23_14205(ytsJ) BSUW23_14480(malS)
                 BSUW23_18290(maeA)
            BHA: BH0399 BH3168
            BAN: BA_0579 BA_1801(ykwA) BA_3145 BA_4848
            BAR: GBAA_0579 GBAA_1801(ykwA) GBAA_3145 GBAA_4848
            BAT: BAS0548 BAS1668 BAS2923 BAS4497
            BAH: BAMEG_1466 BAMEG_2791(malS) BAMEG_4007 BAMEG_4879
            BAI: BAA_0662 BAA_1871(malS) BAA_3192 BAA_4859
            BAL: BACI_c05890(sfcA) BACI_c17950 BACI_c45950(mdh2)
            BCE: BC0580 BC1741 BC4604
            BCA: BCE_0642 BCE_1873(ykwA) BCE_4734
            BCZ: BCZK0492(sfcA) BCZK1615 BCZK4344(mdh)
            BCR: BCAH187_A1922(malS) BCAH187_A4729
            BCB: BCB4264_A0617 BCB4264_A1812(malS) BCB4264_A3134 BCB4264_A4713
            BCU: BCAH820_0635 BCAH820_1848(malS) BCAH820_4718
            BCG: BCG9842_B0524 BCG9842_B3529(malS) BCG9842_B4722
            BCQ: BCQ_0645(sfcA) BCQ_1813(ykwA) BCQ_4407(mdh)
            BCX: BCA_0610 BCA_1808(malS) BCA_4713
            BCY: Bcer98_0499 Bcer98_3287
            BTK: BT9727_0490(sfcA) BT9727_1650 BT9727_4332(mdh)
            BTL: BALH_0520(sfcA) BALH_1583(ykwA) BALH_4186(mdh)
            BTB: BMB171_C0501 BMB171_C1608(malS) BMB171_C4245
            BWE: BcerKBAB4_0493 BcerKBAB4_1666 BcerKBAB4_4433
            BLI: BL00044(malS) BL00406(ytsJ) BL00922(mleA) BL03976(maeA)
            BLD: BLi03071(ytsJ) BLi03139(malS) BLi03953(ywkA) BLi04137(mleA)
            BAY: RBAM_021680(mleA) RBAM_026270(ytsJ) RBAM_026990(malS)
                 RBAM_034210(ywkA)
            BAO: BAMF_2252(mleA) BAMF_2725(ytsJ) BAMF_2787(malS2)
                 BAMF_3542(maeA)
            BAE: BATR1942_10060 BATR1942_12395 BATR1942_12745 BATR1942_16485
            BCL: ABC0918 ABC2723
            BPU: BPUM_2565 BPUM_2635(malS) BPUM_3348(ywkA)
            BPF: BpOF4_03405(mdhP) BpOF4_18115(mdhP2)
            BMQ: BMQ_2057 BMQ_2080 BMQ_4778
            BMD: BMD_2014 BMD_2037 BMD_4764
            BSE: Bsel_1345
            BCO: Bcell_3229
            OIH: OB2176 OB3218
            GKA: GK1440 GK1534
            GTN: GTNG_1301 GTNG_1385
            GWC: GWCH70_1376 GWCH70_1912
            GYM: GYMC10_0780
            GYC: GYMC61_2232 GYMC61_2371
            GYA: GYMC52_1360 GYMC52_1499
            GCT: GC56T3_1976 GC56T3_2108
            GMC: GY4MC1_1629 GY4MC1_2386
            AFL: Aflv_0495 Aflv_2045
            SAU: SA1524
            SAV: SAV1702
            SAW: SAHV_1688
            SAH: SaurJH1_1792
            SAJ: SaurJH9_1758
            SAM: MW1645
            SAS: SAS1629
            SAR: SAR0824 SAR1780
            SAC: SACOL1749
            SAX: USA300HOU_1688
            SAA: SAUSA300_1648
            SAO: SAOUHSC_01810
            SAE: NWMN_1596(maeB)
            SAD: SAAV_1711
            SAB: SAB0723 SAB1560c
            SEP: SE1377
            SER: SERP1265
            SHA: SH1223
            SSP: SSP1065
            SCA: Sca_1307
            SLG: SLGD_01228
            SSD: SPSINT_1458
            LMO: lmo1915
            LMF: LMOf2365_1944(sfcA)
            LMH: LMHCC_0641
            LMC: Lm4b_01932
            LMN: LM5578_2116
            LMY: LM5923_2067
            LIN: lin2029
            LWE: lwe1934(malS)
            LSG: lse_1901(sfcA)
            LSP: Bsph_2148
            BBE: BBR47_13780(ytsJ)
            PJD: Pjdr2_5002
            PPY: PPE_01305 PPE_02985 PPE_03209 PPE_03596 PPE_03731
            PPM: PPSC2_c1401 PPSC2_c3366 PPSC2_c3633 PPSC2_c4210
            AAC: Aaci_0140 Aaci_2141
            BTS: Btus_2435
            LLA: L121483(mleS) L3227(mae)
            LLK: LLKF_0928(mleS)
            LLM: llmg_1638(mleS)
            SPZ: M5005_Spy_0833
            SPM: spyM18_1072
            SPA: M6_Spy0831
            SPB: M28_Spy0810
            SOZ: Spy49_0864
            SAG: SAG1919
            SAN: gbs1906
            SAK: SAK_1878
            SMU: SMU.137(mleS)
            SSA: SSA_0297(mleS)
            SGO: SGO_0372
            SUB: SUB0825
            SDS: SDEG_0873
            SGA: GALLO_2049(mleS)
            LPL: lp_1105(mae) lp_1118(mleS)
            LPJ: JDM1_0911(mae) JDM1_0922(mleS)
            LPS: LPST_C0885(mae) LPST_C0897(mleS)
            LAC: LBA1075
            LSA: LSA0441(mleS)
            LSL: LSL_1313
            LBR: LVIS_2203
            LCA: LSEI_0740
            LCB: LCABL_08060(mleS) LCABL_30690(mae)
            LCZ: LCAZH_0682 LCAZH_2876
            LRE: Lreu_1532
            LRF: LAR_1441
            LRH: LGG_00726(sfcA) LGG_02875
            LRL: LC705_00719(sfcA) LC705_02859(mae)
            PPE: PEPE_1617
            EFA: EF3316
            OOE: OEOE_0418 OEOE_1564
            LME: LEUM_1005
            LCI: LCK_00106 LCK_00751(mleS)
            LKI: LKI_04095 LKI_10035
            LGS: LEGAS_0212(citM) LEGAS_0941(mleS)
            CAC: CA_C1589(malS) CA_C1596(malS)
            CPE: CPE1151
            CPR: CPR_0140
            CTC: CTC00356 CTC02463
            CNO: NT01CX_2051
            CTH: Cthe_0344
            CDF: CD1005
            CDC: CD196_0878
            CDL: CDR20291_0858
            CBO: CBO0210 CBO0246
            CBA: CLB_0251 CLB_0289
            CBH: CLC_0266 CLC_0304
            CBY: CLM_0260
            CBL: CLK_3389
            CBK: CLL_A3577
            CBB: CLD_0518 CLD_0565
            CBI: CLJ_B0258
            CBT: CLH_3371
            CBF: CLI_0275 CLI_0318
            CBE: Cbei_4008 Cbei_5075
            CKL: CKL_2408(maeB)
            CKR: CKR_2124
            CPY: Cphy_0409
            CCE: Ccel_0138
            CLJ: CLJU_c04160(maeB) CLJU_c25360 CLJU_c38460
            CSH: Closa_2356
            CCB: Clocel_0393
            CST: CLOST_2399
            AMT: Amet_1304 Amet_2965 Amet_3229
            STH: STH1319 STH2534
            VPR: Vpar_0439
            AFN: Acfer_0014 Acfer_0693
            DSY: DSY1923
            DHD: Dhaf_0902 Dhaf_3085
            DRM: Dred_2955
            PTH: PTH_2899(sfcA)
            TJR: TherJR_1506
            FMA: FMG_0499
            APR: Apre_0229
            EEL: EUBELI_01448
            ERE: EUBREC_1483
            ELM: ELI_1675
            BPB: bpr_I2277(mdh)
            EHA: Ethha_0739
            RAL: Rumal_0456
            TMR: Tmar_1267
            CLO: HMPREF0868_0752
            TTE: TTE2332(sfcA)
            TEX: Teth514_0830
            TPD: Teth39_0337
            TIT: Thit_2019
            TMT: Tmath_1962
            TBO: Thebr_0347
            CHY: CHY_1369
            MTA: Moth_0401
            ADG: Adeg_0169
            CSC: Csac_2059
            ATE: Athe_1062
            COB: COB47_1463
            CHD: Calhy_1674
            COW: Calow_0879
            CKI: Calkr_1051
            CKN: Calkro_1632
            TOC: Toce_1827
            TTM: Tthe_0395
            CPO: COPRO5265_0583
            NTH: Nther_2399
            HOR: Hore_10070
            HAS: Halsa_0179 Halsa_0180 Halsa_1186
            AAR: Acear_0517 Acear_0955 Acear_1425
            POY: PAM_721(sfcA)
            AYW: AYWB_051(sfcA)
            PML: ATP_00450(sfcA)
            PAL: PAa_0769(sfcA)
            MTU: Rv2332(mez)
            MTC: MT2394(sfcA)
            MRA: MRA_2352(mez)
            MTF: TBFG_12356
            MTB: TBMG_01646(TBMG_01646.1)
            MBO: Mb2360(mez)
            MBB: BCG_2354(mez)
            MBT: JTY_2348(mez)
            MPA: MAP2540c
            MAV: MAV_1381
            MSM: MSMEG_5055
            MUL: MUL_1467(mez) MUL_4503(mez_1)
            MVA: Mvan_4481
            MGI: Mflv_2214
            MAB: MAB_1384
            MMC: Mmcs_3977
            MKM: Mkms_4051
            MJL: Mjls_3991
            MSP: Mspyr1_16460
            MMI: MMAR_3643(mez) MMAR_4197(mez_1)
            CGT: cgR_2895
            CEF: CE2839(malE)
            CKP: ckrop_0541(mez)
            NFA: nfa47090
            RHA: RHA1_ro00492 RHA1_ro02571 RHA1_ro06000 RHA1_ro08928
                 RHA1_ro11316
            RER: RER_41320
            ROP: ROP_22960 ROP_33750 ROP_60600
            REQ: REQ_14600
            GBR: Gbro_0588
            SCO: SCO2951(SCE59.10c) SCO5261(2SC7G11.23)
            SMA: SAV_1514(malS1) SAV_2981 SAV_3870(malS2) SAV_5126
            SGR: SGR_2236 SGR_4581
            SCB: SCAB_29861 SCAB_55931
            ART: Arth_3432 Arth_3994
            AAU: AAur_3406 AAur_3836
            ACH: Achl_3211 Achl_3773
            AAI: AARI_28210 AARI_33440
            RSA: RSal33209_2445
            BCV: Bcav_3529
            BFA: Bfae_08210 Bfae_20210
            KSE: Ksed_00620 Ksed_10480
            SKE: Sked_33400
            CFL: Cfla_2803
            ICA: Intca_0585 Intca_2523 Intca_2854
            PAC: PPA0313 PPA0888
            PAK: HMPREF0675_3355 HMPREF0675_3946
            PFR: PFREUD_08630(PPA0888)
            NCA: Noca_0113 Noca_1727 Noca_2034
            KFL: Kfla_1778 Kfla_5195
            TFU: Tfu_0562 Tfu_2390
            NDA: Ndas_0366 Ndas_3685
            TCU: Tcur_3684 Tcur_3884
            SRO: Sros_1706 Sros_8298
            FRA: Francci3_3751
            FRE: Franean1_0980
            FRI: FraEuI1c_0817
            FAL: FRAAL5985
            ACE: Acel_1647
            NML: Namu_0264 Namu_1419 Namu_4139
            GOB: Gobs_0212 Gobs_2964 Gobs_4173
            SEN: SACE_0563 SACE_6415
            SVI: Svir_30630 Svir_34210
            TBI: Tbis_0923 Tbis_2900
            AMD: AMED_7961(sfcA) AMED_8523(sfcA)
            AMI: Amir_0465 Amir_6279
            STP: Strop_1448 Strop_3695
            SAQ: Sare_1406 Sare_4075
            MAU: Micau_1551 Micau_5233
            MIL: ML5_1812 ML5_3059
            CAI: Caci_1467 Caci_4404 Caci_7700
            SNA: Snas_4565 Snas_5158
            AHE: Arch_0422
            BDE: BDP_1119
            RXY: Rxyl_1110
            CWO: Cwoe_0486 Cwoe_2866
            AFO: Afer_0622 Afer_1947
            SHI: Shel_05030
            APV: Apar_1191
            OLS: Olsu_0379
            TDE: TDE2446
            ACA: ACP_2736
            SUS: Acid_2954
            PMZ: HMPREF0659_A5560
            SRU: SRU_1786
            SRM: SRM_01998
            AAS: Aasi_0353
            LBA: Lebu_1156
            STR: Sterm_1956
            IPO: Ilyop_2027
            RBA: RB307
            PLM: Plim_1786
            EMI: Emin_0296
            RSD: TGRD_287
            TAI: Taci_0215 Taci_0810
            ACO: Amico_0137 Amico_1353 Amico_1790
            SYN: slr0721(me)
            SYC: syc0256_c
            SYF: Synpcc7942_1297
            SYP: SYNPCC7002_A0448
            CYA: CYA_0662
            CYB: CYB_0613
            TEL: tll1440
            MAR: MAE_07860
            CYT: cce_3246
            CYP: PCC8801_2893
            CYC: PCC7424_1195
            CYN: Cyan7425_0554
            CYH: Cyan8802_3203
            CYJ: Cyan7822_4201
            GVI: gll2149
            ANA: alr4596
            NPU: Npun_F1023
            AVA: Ava_2458
            NAZ: Aazo_1656
            TER: Tery_3983
            AMR: AM1_3904
            CPH: Cpha266_1271
            CLI: Clim_1316
            PLT: Plut_0896
            PPH: Ppha_1089
            CTS: Ctha_2660
            RRS: RoseRS_2286 RoseRS_3704
            RCA: Rcas_2490 Rcas_3529
            CAU: Caur_1614
            CAG: Cagg_3355
            CHL: Chy400_1751
            TRO: trd_A0309
            STI: Sthe_3014
            DRA: DR_2583 DR_A0276
            DGE: Dgeo_2154
            DDR: Deide_20160
            DMR: Deima_1129
            TTH: TTC0144
            TTJ: TTHA0520
            TSC: TSC_c06850(sfcA)
            MRB: Mrub_0979
            MSV: Mesil_2079
            OPR: Ocepr_1163
            TMA: TM0542
            TPT: Tpet_0379
            TLE: Tlet_0836
            TRQ: TRQ2_0395
            TNA: CTN_0126
            TNP: Tnap_0322
            FNO: Fnod_0471
            PMO: Pmob_0949
            KOL: Kole_0487
            DTH: DICTH_0823
            DTU: Dtur_0967
            TYE: THEYE_A0769
            NDE: NIDE2442(maeA) NIDE3846(maeA2)
            DAP: Dacet_1216
            CNI: Calni_0732
            MAC: MA1735
            MBA: Mbar_A3045
            MMA: MM_2632
            MMH: Mmah_0476
            MTP: Mthe_0409
            MHU: Mhun_0147
            MPI: Mpet_1092 Mpet_1335
            MPL: Mpal_0242
            AFU: AF1727(mae)
            APO: Arcpr_1849
            TAC: Ta0456m
            TVO: TVN0768
            PTO: PTO0957
            PAB: PAB1792(mae)
            PFU: PF1026
            TKO: TK1963
            TGA: TGAM_0399(maeB)
            TSI: TSIB_0123
            TBA: TERMP_01602
            ABI: Aboo_0985
            APE: APE_0392
            IAG: Igag_1596
            HBU: Hbut_0153
            SSO: SSO2869
            STO: ST0114 ST0278
            SAI: Saci_2154
            SIS: LS215_2611
            SIA: M1425_2439
            SIM: M1627_2515
            SID: M164_2444
            SIY: YG5714_2590
            SIN: YN1551_0317
            SII: LD85_2753
            PAI: PAE1688
            PIS: Pisl_1691
            PCL: Pcal_0564
            PAS: Pars_2233
            CMA: Cmaq_0373
            VDI: Vdis_0932
            ASC: ASAC_0512 ASAC_0978
            KCR: Kcr_0950
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.38
            IUBMB Enzyme Nomenclature: 1.1.1.38
            ExPASy - ENZYME nomenclature database: 1.1.1.38
            BRENDA, the Enzyme Database: 1.1.1.38
            CAS: 9080-52-8
///
ENTRY       EC 1.1.1.39                 Enzyme
NAME        malate dehydrogenase (decarboxylating);
            'malic' enzyme;
            pyruvic-malic carboxylase;
            NAD-specific malic enzyme;
            NAD-malic enzyme
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-malate:NAD+ oxidoreductase (decarboxylating)
REACTION    (S)-malate + NAD+ = pyruvate + CO2 + NADH [RN:R00214]
ALL_REAC    R00214
SUBSTRATE   (S)-malate [CPD:C00149];
            NAD+ [CPD:C00003]
PRODUCT     pyruvate [CPD:C00022];
            CO2 [CPD:C00011];
            NADH [CPD:C00004]
COMMENT     Does not decarboxylate added oxaloacetate.
REFERENCE   1  [PMID:13416294]
  AUTHORS   SAZ HJ, HUBBARD JA.
  TITLE     The oxidative decarboxylation of malate by Ascaris lumbricoides.
  JOURNAL   J. Biol. Chem. 225 (1957) 921-33.
  ORGANISM  Ascaris lumbricoides
PATHWAY     ec00620  Pyruvate metabolism
            ec00710  Carbon fixation in photosynthetic organisms
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00028  malate dehydrogenase (decarboxylating)
GENES       ATH: AT2G13560 AT4G00570
            POP: POPTR_731028 POPTR_816506
            RCU: RCOM_0658870 RCOM_1614520
            VVI: 100241371 100261633
            OSA: 4343294 4349051
            SBI: SORBI_01g017790 SORBI_02g033920
            ZMA: 100501486
            PPP: PHYPADRAFT_198570
            CRE: CHLREDRAFT_196833(MME1)
            MLO: mlr0809
            MES: Meso_1536
            SME: SMc00169(dme)
            ATU: Atu1652(maeB)
            RET: RHE_CH02355(dme)
            RLE: RL2671(maeB)
            BHE: BH07470
            BQU: BQ05320
            BBK: BARBAKC583_0622(dme)
            BTR: Btr_0109(maeB1) Btr_1325(maeB2)
            SIL: SPO2932
            SPY: SPy_1110
            SPG: SpyM3_0771
            SPS: SPs0971
            SPH: MGAS10270_Spy0949
            SPI: MGAS10750_Spy0984
            SPJ: MGAS2096_Spy0908
            SPK: MGAS9429_Spy0952
            SPF: SpyM50955
            LCA: LSEI_2866
            EFA: EF1206
            NPH: NP0132A(mdh_1)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.39
            IUBMB Enzyme Nomenclature: 1.1.1.39
            ExPASy - ENZYME nomenclature database: 1.1.1.39
            BRENDA, the Enzyme Database: 1.1.1.39
            CAS: 9028-46-0
///
ENTRY       EC 1.1.1.40                 Enzyme
NAME        malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+);
            'malic' enzyme;
            pyruvic-malic carboxylase;
            malate dehydrogenase (decarboxylating, NADP+);
            NADP+-linked decarboxylating malic enzyme;
            NADP+-malic enzyme;
            NADP+-specific malic enzyme;
            NADP+-specific malate dehydrogenase;
            malate dehydrogenase (NADP+, decarboxylating);
            L-malate:NADP+ oxidoreductase;
            malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)
REACTION    (S)-malate + NADP+ = pyruvate + CO2 + NADPH [RN:R00216]
ALL_REAC    R00216;
            (other) R00217
SUBSTRATE   (S)-malate [CPD:C00149];
            NADP+ [CPD:C00006]
PRODUCT     pyruvate [CPD:C00022];
            CO2 [CPD:C00011];
            NADPH [CPD:C00005]
COMMENT     Also decarboxylates added oxaloacetate.
REFERENCE   1  [PMID:13084629]
  AUTHORS   HARARY I, KOREY SR, OCHOA S.
  TITLE     Biosynthesis of dicarboxylic acids by carbon dioxide fixation. VII.
            Equilibrium of malic enzyme reaction.
  JOURNAL   J. Biol. Chem. 203 (1953) 595-604.
  ORGANISM  pigeon, Lactobacillus arabinosus
REFERENCE   2  [PMID:18871257]
  AUTHORS   OCHOA S, MEHLER AH, KORNBERG A
  TITLE     Biosynthesis of dicarboxylic acids by carbon dioxide fixation;
            isolation and properties of an enzyme from pigeon liver catalyzing
            the reversible oxidative decarboxylation of 1-malic acid.
  JOURNAL   J. Biol. Chem. 174 (1948) 979-1000.
REFERENCE   3  [PMID:13563505]
  AUTHORS   RUTTER WJ, LARDY HA.
  TITLE     Purification and properties of pigeon liver malic enzyme.
  JOURNAL   J. Biol. Chem. 233 (1958) 374-82.
  ORGANISM  pigeon
REFERENCE   4  [PMID:13834656]
  AUTHORS   STICKLAND RG.
  TITLE     Some properties of the malic enzyme of pigeon liver. 1. Conversion
            of malate into pyruvate.
  JOURNAL   Biochem. J. 73 (1959) 646-54.
  ORGANISM  pigeon
REFERENCE   5  [PMID:13834657]
  AUTHORS   STICKLAND RG.
  TITLE     Some properties of the malic enzyme of pigeon liver. 2. Synthesis of
            malate from pyruvate.
  JOURNAL   Biochem. J. 73 (1959) 654-9.
  ORGANISM  pigeon
REFERENCE   6  [PMID:13842495]
  AUTHORS   WALKER DA.
  TITLE     Physiological studies on acid metabolism. 7. Malic enzyme from
            Kalanchoe crenata: effects of carbon dioxide concentration.
  JOURNAL   Biochem. J. 74 (1960) 216-23.
  ORGANISM  Kalanchoe crenata
PATHWAY     ec00620  Pyruvate metabolism
            ec00710  Carbon fixation in photosynthetic organisms
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00029  malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+)
GENES       HSA: 10873(ME3) 4199(ME1)
            PTR: 451467(ME3) 462853(ME1)
            PON: 100452211
            MCC: 694739(ME1) 704422(ME3)
            MMU: 109264(Me3) 17436(Me1)
            RNO: 24552(Me1) 361602(Me3)
            CFA: 403709(ME1) 485151(ME3)
            AML: 100465272 100470128(ME3)
            BTA: 525813(ME3) 540985(ME1)
            SSC: 100520040(ME3) 397538(ME1)
            ECB: 100061008 100070127
            MDO: 100024530 100025953 100029738
            OAA: 100082160
            GGA: 374189(ME1)
            TGU: 100219269 100228758
            XLA: 495390(me3)
            XTR: 100135099(me3) 100145399(me1) 100489590
            DRE: 492719(me3) 768196(me1)
            BFO: BRAFLDRAFT_115266
            SPU: 575178
            DME: Dmel_CG10120(Men) Dmel_CG5889(Mdh) Dmel_CG7848
                 Dmel_CG7964(Menl-1) Dmel_CG7969(Menl-2)
            DPO: Dpse_GA10087 Dpse_GA15647 Dpse_GA19206 Dpse_GA20630
            DAN: Dana_GF11263 Dana_GF11264 Dana_GF11265 Dana_GF18099
                 Dana_GF23280
            DER: Dere_GG11530 Dere_GG17100 Dere_GG22266 Dere_GG22267
                 Dere_GG22268
            DPE: Dper_GL11343 Dper_GL11344 Dper_GL11345 Dper_GL23167
                 Dper_GL23904
            DSE: Dsec_GM10372 Dsec_GM20055 Dsec_GM20056 Dsec_GM20057
                 Dsec_GM25984
            DSI: Dsim_GD20544(Dsim_Men) Dsim_GD25536 Dsim_GD25537 Dsim_GD25538
            DWI: Dwil_GK10867 Dwil_GK11883 Dwil_GK21699
            DYA: Dyak_GE14059 Dyak_GE14060 Dyak_GE14061 Dyak_GE23720
                 Dyak_GE24490
            DGR: Dgri_GH17523 Dgri_GH19210 Dgri_GH20645 Dgri_GH20647
            DMO: Dmoj_GI19011 Dmoj_GI19012 Dmoj_GI23201 Dmoj_GI24244
            DVI: Dvir_GJ10817 Dvir_GJ19974 Dvir_GJ22862
            AGA: AgaP_AGAP000184 AgaP_AGAP004159
            AAG: AaeL_AAEL001091 AaeL_AAEL005790
            CQU: CpipJ_CPIJ009607 CpipJ_CPIJ012341
            AME: 409682(Mdh) 411813(Men)
            NVI: 100121413(NV16370) 100124190(NV10467)
            TCA: 657607 657686
            API: 100163010 100165091
            ISC: IscW_ISCW011260
            CEL: Y48B6A.12
            BMY: Bm1_53260 Bm1_53540
            SMM: Smp_128360
            NVE: NEMVE_v1g173675
            HMG: 100197083
            TAD: TRIADDRAFT_50795
            ATH: AT1G79750 AT2G19900 AT5G11670 AT5G25880
            POP: POPTR_561733 POPTR_711993 POPTR_737670 POPTR_825669
                 POPTR_844184
            RCU: RCOM_0801560 RCOM_1049930 RCOM_1489870
            VVI: 100233075(VVME2) 100233140(NADP-ME)
            OSA: 4324717 4326552 4326769 4338007
            SBI: SORBI_03g003220 SORBI_03g034280 SORBI_09g005810
            ZMA: 100284598 100286036(AY104511) 542209(me4) 542233(me3)
                 542331(me2)
            PPP: PHYPADRAFT_111236 PHYPADRAFT_179808 PHYPADRAFT_201540
            CRE: CHLREDRAFT_126820(MME6) CHLREDRAFT_147722(MME2)
                 CHLREDRAFT_196351(MME5) CHLREDRAFT_196831(MME4)
                 CHLREDRAFT_196832(MME3)
            VCN: VOLCADRAFT_77886 VOLCADRAFT_78607
            OLU: OSTLU_12474 OSTLU_41212
            OTA: Ot01g00040 Ot04g03750 Ot06g03980 Ot07g00930
            CME: CMJ051C
            NCR: NCU03651
            PAN: PODANSg8969
            MGR: MGG_08173(MG08173.4)
            FGR: FG07191.1
            SSL: SS1G_08827
            BFU: BC1G_09224 BC1G_12552
            ANI: AN6168.2
            AFM: AFUA_2G08280
            NFI: NFIA_083930
            AOR: AO090011000876
            ANG: An05g00930
            AFV: AFLA_046740
            ACT: ACLA_080110
            PCS: Pc13g04510
            CIM: CIMG_00874
            CPW: CPC735_054470
            URE: UREG_00830
            PNO: SNOG_03133
            TML: GSTUM_00003300001
            CNE: CNF03780 CNN01010
            LBC: LACBIDRAFT_188199 LACBIDRAFT_297458
            CCI: CC1G_07119 CC1G_07719
            SCM: SCHCODRAFT_79137
            UMA: UM02307.1
            MGL: MGL_2702
            MBR: MONBRDRAFT_33221
            NGR: NAEGRDRAFT_59395
            DDI: DDB_G0272524(malA)
            CPV: cgd5_750
            CHO: Chro.50314
            TVA: TVAG_340290
            PTI: PHATRDRAFT_51970 PHATRDRAFT_56501(ME1)
            TPS: THAPSDRAFT_34030(MAO1)
            PIF: PITG_17753
            ECO: b2463(maeB)
            ECJ: JW2447(maeB)
            ECD: ECDH10B_2628(maeB)
            EBW: BWG_2225(maeB)
            ECE: Z3719
            ECS: ECs3325
            ECF: ECH74115_3684(maeB)
            ETW: ECSP_3401(maeB)
            EOJ: ECO26_3506(maeB)
            EOI: ECO111_3183(maeB)
            EOH: ECO103_2972(maeB)
            ECG: E2348C_2697(maeB)
            EOK: G2583_2985(maeB)
            ECC: c2988
            ECP: ECP_2475
            ECI: UTI89_C2787(maeB)
            ECV: APECO1_4094
            ECX: EcHS_A2592(maeB)
            ECW: EcE24377A_2741(maeB)
            ECM: EcSMS35_2609(maeB)
            ECY: ECSE_2744
            ECR: ECIAI1_2511(maeB)
            ECQ: ECED1_2896(maeB)
            ECK: EC55989_2743(maeB)
            ECT: ECIAI39_2600(maeB)
            EUM: ECUMN_2775(maeB)
            ECZ: ECS88_2642(maeB)
            ECL: EcolC_1214
            EBR: ECB_02354(maeB)
            EBD: ECBD_1227
            EFE: EFER_0716(maeB)
            STY: STY2709(maeB)
            STT: t0387(maeB)
            STM: STM2472(maeB)
            SPT: SPA0397(maeB)
            SEK: SSPA0371
            SPQ: SPAB_00481
            SEI: SPC_1189(maeB)
            SEC: SC2467(maeB)
            SEH: SeHA_C2731
            SEE: SNSL254_A2664
            SEW: SeSA_A2705(maeB)
            SEA: SeAg_B2616
            SED: SeD_A2838
            SEG: SG2502(maeB)
            SET: SEN2451(maeB)
            SES: SARI_00411
            YPE: YPO3034(maeB)
            YPK: y1449
            YPA: YPA_2222
            YPN: YPN_1351
            YPM: YP_2657(sfcA2)
            YPP: YPDSF_2139
            YPG: YpAngola_A2786(maeB)
            YPZ: YPZ3_2673
            YPS: YPTB2756(maeB)
            YPI: YpsIP31758_1277(maeB)
            YPY: YPK_1391
            YPB: YPTS_2859
            YEN: YE1162(maeB)
            SFL: SF2505
            SFX: S2656
            SFV: SFV_2507
            SSN: SSON_2543
            SBO: SBO_2478
            SBC: SbBS512_E2829(maeB)
            SDY: SDY_2645
            ECA: ECA0871(maeB)
            PCT: PC1_0754
            PWA: Pecwa_0990
            EBI: EbC_33060(maeB)
            PLU: plu2719(maeB)
            PAY: PAU_01820(maeB)
            ENT: Ent638_2958
            ENC: ECL_03760
            ESC: Entcl_1304
            ESA: ESA_00790
            CTU: Ctu_30530(maeB)
            KPN: KPN_02797(maeB)
            KPE: KPK_1340(maeB)
            KPU: KP1_4048(maeB)
            KVA: Kvar_1258
            CKO: CKO_00332
            CRO: ROD_24111(maeB)
            SPE: Spro_3472
            PMR: PMI1552(maeB)
            EIC: NT01EI_1233
            ETR: ETAE_1122(maeB)
            DDA: Dd703_3213
            DDC: Dd586_0779
            DDD: Dda3937_01399(maeB)
            DZE: Dd1591_3292
            XBO: XBJ1_2590(maeB)
            XNE: XNC1_2651(maeB)
            PAM: PANA_2778(maeB)
            PAO: Pat9b_2854
            RIP: RIEPE_0182
            HIN: HI1245
            HIT: NTHI1920(mao2)
            HIP: CGSHiEE_03975
            HIQ: CGSHiGG_01785
            HIF: HIBPF06200
            HIL: HICON_14810
            HDU: HD1247(maeA)
            HAP: HAPS_2176(sfcA)
            HSO: HS_0465(mdh)
            HSM: HSM_0764
            PMU: PM0002(mdh_1)
            MSU: MS0390(sfcA)
            APL: APL_0486(maeB)
            APA: APP7_0564
            ASU: Asuc_0669
            AAP: NT05HA_0023
            AAT: D11S_2005
            XFA: XF0977
            XFT: PD0272(maeB)
            XFM: Xfasm12_0295
            XFN: XfasM23_0265
            XCC: XCC3345(maeB)
            XCB: XC_0821
            XCA: xccb100_0853(maeB)
            XCV: XCV3598(maeB)
            XAC: XAC3470(maeB)
            XOO: XOO1118(maeB)
            XOM: XOO_1015
            XOP: PXO_02395
            XAL: XALc_0739(maeB)
            SML: Smlt3940(maeB)
            SMT: Smal_3352
            PSU: Psesu_2730
            VCH: VC2681
            VCO: VC0395_A2254
            VCM: VCM66_2601
            VCJ: VCD_001687
            VVU: VV1_1361
            VVY: VV3010
            VVM: VVM_00577
            VPA: VP2767
            VHA: VIBHAR_00051
            VSP: VS_2896
            VEX: VEA_002303
            VFI: VF_2272(maeB)
            VFM: VFMJ11_2384
            VSA: VSAL_I2745(maeB)
            PPR: PBPRA0259
            PAE: PA5046
            PAU: PA14_66680(maeB)
            PAP: PSPA7_5783
            PAG: PLES_54361
            PPU: PP_5085(maeB)
            PPF: Pput_4958
            PPG: PputGB1_5135
            PPW: PputW619_0380 PputW619_2300
            PSB: Psyr_0401
            PSP: PSPPH_0388(maeB)
            PFS: PFLU0405
            PEN: PSEEN0327
            PMY: Pmen_0540
            PSA: PST_0550(maeB)
            AVN: Avin_43250(maeB2) Avin_45330(maeB)
            PAR: Psyc_1367(maeB)
            PCR: Pcryo_0997
            PRW: PsycPRwf_1269
            ACI: ACIAD2287
            ACD: AOLE_05325
            ACB: A1S_2338
            ABM: ABSDF1183
            ABY: ABAYE1138
            ABC: ACICU_02540
            ABN: AB57_2773
            ABB: ABBFA_001103
            MCT: MCR_0455(maeB)
            SDN: Sden_3353
            SFR: Sfri_3757
            SAZ: Sama_0448
            SBL: Sbal_3841
            SBM: Shew185_0478
            SBN: Sbal195_0499
            SBP: Sbal223_0502
            SLO: Shew_0383
            SPC: Sputcn32_0554
            SSE: Ssed_0538
            SPL: Spea_3774
            SHE: Shewmr4_3492
            SHM: Shewmr7_0460
            SHW: Sputw3181_3618
            SHL: Shal_3859
            SWD: Swoo_4423
            SWP: swp_0481
            SVO: SVI_0280
            ILO: IL2463
            CPS: CPS_0331 CPS_2051 CPS_4881
            PHA: PSHAa2725(maeB)
            PAT: Patl_4187
            PSM: PSM_A0300(maeB)
            SDE: Sde_0661
            MAQ: Maqu_0824
            AMC: MADE_03522
            PIN: Ping_1744
            TTU: TERTU_1358
            FBL: Fbal_3519
            LPF: lpl0687
            LPP: lpp0705
            LPC: LPC_2643(mao2)
            LPA: lpa_01017(sfcA)
            LLO: LLO_2561
            NOC: Noc_0244 Noc_1582
            NHL: Nhal_1352 Nhal_3894
            NWA: Nwat_0342 Nwat_1551
            ALV: Alvin_3051
            AEH: Mlg_0246
            HHA: Hhal_1029
            TGR: Tgr7_1729 Tgr7_2970
            TKM: TK90_2378
            HNA: Hneap_2058
            HCH: HCH_05974(scfA)
            CSA: Csal_0605
            HEL: HELO_3763(maeB)
            ABO: ABO_2239(maeB)
            MMW: Mmwyl1_4123
            AHA: AHA_4195
            ASA: ASA_0131(maeB)
            TAU: Tola_0482
            DNO: DNO_0020(maeB)
            AFE: Lferr_0809
            AFR: AFE_0660
            VOK: COSY_0748(maeB)
            GPB: HDN1F_20620
            NMI: NMO_0556(maeA)
            NGK: NGK_0374
            NLA: NLA_15710(maeA)
            CVI: CV_0916(maeB)
            LHK: LHK_01391(maeB)
            RSO: RSc2123(maeB1) RSc2767(maeB2)
            RSC: RCFBP_10693(maeB) RCFBP_11271(maeB)
            RSL: RPSI07_0742(maeB) RPSI07_1300 RPSI07_1310(maeB)
                 RPSI07_1528(maeB)
            RPI: Rpic_2263 Rpic_3013
            RPF: Rpic12D_1940 Rpic12D_2603
            REU: Reut_A2441 Reut_A2847
            REH: H16_A1002(maeB) H16_A3153(maeA)
            RME: Rmet_0878 Rmet_3046
            CTI: RALTA_A0986(maeB) RALTA_A2627(maeB2)
            BMA: BMA2477(maeB1) BMA2586(maeB-2)
            BMV: BMASAVP1_A0396(maeB1) BMASAVP1_A3123(maeB-2) BMASAVP1_A3533
            BML: BMA10229_A1256(maeB1) BMA10229_A1969(maeB-2)
            BMN: BMA10247_3309(maeB1) BMA10247_3524
            BPS: BPSL2959(maeB) BPSL3242
            BPM: BURPS1710b_0019(maeB-2) BURPS1710b_3474(maeB)
            BPL: BURPS1106A_3476 BURPS1106A_3849
            BPD: BURPS668_3439 BURPS668_3788
            BPR: GBP346_A3620 GBP346_A3975
            BTE: BTH_I1189 BTH_I3110
            BVI: Bcep1808_0300 Bcep1808_0605 Bcep1808_3396
            BUR: Bcep18194_A3417 Bcep18194_A3713 Bcep18194_B2662
            BCN: Bcen_0148 Bcen_2788
            BCH: Bcen2424_0318 Bcen2424_0631 Bcen2424_3496
            BCM: Bcenmc03_0298 Bcenmc03_0599 Bcenmc03_4026
            BCJ: BCAL0205 BCAL3395(maeB) BCAM0519(maeB)
            BAM: Bamb_0237 Bamb_0532 Bamb_4462
            BAC: BamMC406_0245 BamMC406_0556 BamMC406_4982
            BMU: Bmul_0220 Bmul_2754
            BMJ: BMULJ_00483(maeB) BMULJ_03043(maeB)
            BXE: Bxe_A0283 Bxe_A0557 Bxe_A3355
            BPH: Bphy_2604 Bphy_2869
            BPY: Bphyt_3399 Bphyt_3674
            BGL: bglu_1g02290 bglu_1g05290 bglu_2g14660
            BGE: BC1002_2658 BC1002_2927 BC1002_5901
            BRH: RBRH_00373 RBRH_03194
            PNU: Pnuc_0224
            BPE: BP1120(maeB) BP3456(maeB)
            BPA: BPP0832(maeB) BPP3221(maeB)
            BBR: BB0926(maeB) BB1376(maeB) BB3673(maeB)
            BPT: Bpet1828(maeB1) Bpet3628(maeB2)
            BAV: BAV0859(maeB1) BAV1200(maeB) BAV3422(maeB2)
            AXY: AXYL_01637(maeB1) AXYL_05121(maeB2) AXYL_05297(maeB3)
            TEQ: TEQUI_1308
            RFR: Rfer_0093 Rfer_1424
            POL: Bpro_1421 Bpro_4858
            PNA: Pnap_1010 Pnap_4071
            AAV: Aave_1095 Aave_4759
            AJS: Ajs_1112 Ajs_4106
            DIA: Dtpsy_1033 Dtpsy_3465
            VEI: Veis_0807 Veis_1646
            DAC: Daci_2106 Daci_6030
            VAP: Vapar_3958 Vapar_5270 Vapar_5338
            VPE: Varpa_4575 Varpa_5991
            CTT: CtCNB1_3723 CtCNB1_4796
            ADN: Alide_3112 Alide_4374
            MPT: Mpe_A0207
            HAR: HEAR0648
            MMS: mma_0611(maeB)
            HSE: Hsero_1145(maeB) Hsero_3360(maeB)
            ZIN: ZICARI_081(maeB)
            LCH: Lcho_0359 Lcho_3916
            TIN: Tint_0097
            NEU: NE0438
            NET: Neut_0596
            EBA: ebA4043(maeB2) ebA4392(maeB1)
            AZO: azo0821(maeB1) azo3211(maeB2)
            DAR: Daro_0666 Daro_3943
            TMZ: Tmz1t_1093 Tmz1t_1580
            TBD: Tbd_1181
            MMB: Mmol_0756
            MEH: M301_0693
            MEI: Msip34_2203
            MEP: MPQ_2154(sfcA)
            APP: CAP2UW1_0018 CAP2UW1_0772
            SLT: Slit_0450
            GCA: Galf_2598
            CJR: CJE1479
            CJJ: CJJ81176_1304
            CJU: C8J_1230
            CJN: ICDCCJ_1235
            CJD: JJD26997_0435
            CFF: CFF8240_1560
            CCV: CCV52592_0547
            CHA: CHAB381_0112
            CCO: CCC13826_0241(tktA)
            CLA: Cla_1292(mez)
            ANT: Arnit_1863
            SDL: Sdel_2195
            NIS: NIS_1640
            SUN: SUN_0515
            NSA: Nitsa_1263
            NAM: NAMH_1202
            GSU: GSU1700(maeB)
            GME: Gmet_1637
            GUR: Gura_2073
            GBM: Gbem_1455(maeB-2)
            GEO: Geob_0240 Geob_2882
            GEM: GM21_2798
            DVU: DVU0414
            DVL: Dvul_2520
            DVM: DvMF_1539
            DDE: Dde_1253 Dde_3637
            DMA: DMR_34340
            DSA: Desal_0725
            DAS: Daes_2995
            LIP: LI0351(mdh)
            DBA: Dbac_3061
            DRT: Dret_0778
            BBA: Bd1833(mdh) Bd1834
            DPR: Despr_1999
            DAL: Dalk_0610
            ADE: Adeh_3930
            ACP: A2cp1_4071
            AFW: Anae109_0502
            ANK: AnaeK_4039
            SCL: sce9116(maeB2)
            HOH: Hoch_4217
            SFU: Sfum_2777
            DBR: Deba_2141
            RPR: RP373
            RTY: RT0361(tme)
            RCM: A1E_03585
            RCO: RC0507(tme)
            RFE: RF_0584(tme)
            RAK: A1C_02765
            RRI: A1G_02875
            RRJ: RrIowa_0602
            RMS: RMA_0527(tme)
            RPK: RPR_06045
            RAF: RAF_ORF0474(tme)
            RBE: RBE_0869(tme)
            RBO: A1I_02555
            OTT: OTT_0582(tme)
            WOL: WD0488(maeB)
            WBM: Wbm0674
            WRI: WRi_002570
            WPI: WPa_1210(maeB)
            AMA: AM024(maeB)
            AMF: AMF_020(maeB)
            ACN: ACIS_00022(maeB)
            APH: APH_0042
            ERU: Erum1200(maeB)
            ERW: ERWE_CDS_01170(tme)
            ERG: ERGA_CDS_01130(tme)
            ECN: Ecaj_0118
            ECH: ECH_0175
            NSE: NSE_0420
            NRI: NRI_0399
            PUB: SAR11_0375(maeB)
            MLO: mlr5329
            MCI: Mesci_0182 Mesci_4113
            MES: Meso_4030
            PLA: Plav_3598
            SME: SMc01126(tme)
            SMD: Smed_0029 Smed_1558
            RHI: NGR_c00300 NGR_c16880(dme)
            ATU: Atu3356
            ARA: Arad_0638(pta) Arad_2672(dme)
            AVI: Avi_1891(maeB)
            RET: RHE_CH00389(tme)
            REC: RHECIAT_CH0000430(maeB) RHECIAT_CH0002453(dme)
            RLE: RL0407(maeB)
            RLT: Rleg2_0033 Rleg2_1993
            RLG: Rleg_0048 Rleg_2206
            LAS: CLIBASIA_00080(maeB)
            LSO: CKC_04950
            BME: BMEI0967 BMEI1802 BMEI1803
            BMI: BMEA_A1058
            BMF: BAB1_1036
            BMB: BruAb1_1022(maeB)
            BMC: BAbS19_I01360 BAbS19_I01370 BAbS19_I09620
            BMS: BR1017(maeB)
            BMT: BSUIS_A1060
            BOV: BOV_0984(maeB)
            BCS: BCAN_A1032
            BMR: BMI_I1020(maeB) BMI_I149
            OAN: Oant_0158 Oant_2100
            BJA: blr3726(tme) blr4145(dme)
            BRA: BRADO3367 BRADO5322
            BBT: BBta_3876 BBta_5810
            RPA: RPA3042(mao)
            RPB: RPB_2497
            RPC: RPC_2337
            RPD: RPD_2946
            RPE: RPE_3275
            RPT: Rpal_3452
            RPX: Rpdx1_2385
            NWI: Nwi_1587
            NHA: Nham_2110
            OCA: OCAR_6333(maeB)
            BHE: BH01010(maeB)
            BQU: BQ00940(maeB)
            BBK: BARBAKC583_1298
            BGR: Bgr_00990(maeB1) Bgr_11560(maeB2)
            BCD: BARCL_0835(maeB)
            XAU: Xaut_3143 Xaut_3937
            AZC: AZC_0119 AZC_3656
            SNO: Snov_1122
            MEX: Mext_0827
            MEA: Mex_1p0594(dme)
            MDI: METDI0965(dme)
            MRD: Mrad2831_0498
            MET: M446_1243 M446_2472 M446_6546
            MPO: Mpop_0750
            MCH: Mchl_0787
            MNO: Mnod_2174 Mnod_2328 Mnod_7102
            BID: Bind_2063
            MSL: Msil_0083
            RVA: Rvan_0258 Rvan_1566
            CCR: CC_2622 CC_3549
            CCS: CCNA_02704 CCNA_03663
            CAK: Caul_3722 Caul_4968
            CSE: Cseg_0131 Cseg_1074
            PZU: PHZ_c3418
            BSB: Bresu_0511
            AEX: Astex_0036
            SIL: SPO0012(maeB)
            SIT: TM1040_1573 TM1040_2877
            RSP: RSP_1217 RSP_1593
            RSH: Rsph17029_0246 Rsph17029_2878
            RSQ: Rsph17025_0274 Rsph17025_2654
            RSK: RSKD131_2615 RSKD131_2993
            RCP: RCAP_rcc00443(maeB1) RCAP_rcc03496(maeB2)
            JAN: Jann_0210 Jann_2989
            RDE: RD1_0421(tme)
            PDE: Pden_0848 Pden_2224
            DSH: Dshi_0826 Dshi_3467(maeB)
            KVU: EIO_3307
            MMR: Mmar10_3020
            HNE: HNE_0296(maeB)
            HBA: Hbal_3099
            NAR: Saro_3291
            SAL: Sala_2792
            SWI: Swit_1904 Swit_2760
            SJP: SJA_C1-21620(maeB) SJA_C1-35000(maeB)
            ELI: ELI_14205
            ACR: Acry_2289
            GDI: GDI_1628(mod1)
            GDJ: Gdia_1833
            APT: APA01_01110
            RRU: Rru_A3542
            RCE: RC1_0405(dme) RC1_3260(tme)
            MAG: amb0289 amb0720
            AZL: AZL_000200(maeB) AZL_a05660(maeB) AZL_a08520(maeB)
            PBR: PB2503_04852
            APB: SAR116_1600
            MGM: Mmc1_0767
            DIN: Selin_0305
            SSM: Spirs_0987
            LIL: LA_0181(sfcA)
            LIC: LIC10160(maeB)
            LBI: LEPBI_I0143(maeB)
            LBF: LBF_0140(sfcA)
            BHY: BHWA1_01613(mdh)
            BPO: BP951000_1737(mdh)
            SUS: Acid_4539
            BTH: BT_1969
            BFR: BF3605
            BFS: BF3408(maeB)
            BVU: BVU_0245
            BHL: Bache_3198
            PGI: PG0279(maeB)
            PGN: PGN_1685
            PDI: BDI_1733
            PPN: Palpr_0613
            APS: CFPG_496
            PMZ: HMPREF0659_A6863
            CHU: CHU_0027(maeB)
            DFE: Dfer_0248
            SLI: Slin_2911
            LBY: Lbys_0673
            MTT: Ftrac_3335
            CPI: Cpin_1209
            PHE: Phep_3833
            GFO: GFO_0179(maeB)
            FJO: Fjoh_1651
            FPS: FP2123(maeB)
            COC: Coch_0765
            RBI: RB2501_03625
            ZPR: ZPR_0588
            CAT: CA2559_01220
            RAN: Riean_1470
            FBC: FB2170_03030
            CAO: Celal_2073
            FBA: FIC_02253
            SMG: SMGWSS_145(maeA)
            SMH: DMIN_01410
            SUM: SMCARI_161(maeA)
            BBL: BLBBGE_412(maeB)
            BPI: BPLAN_230(maeB)
            FSU: Fisuc_0790
            OTE: Oter_3293
            AMU: Amuc_2106
            GAU: GAU_2389
            CYT: cce_4356
            CYP: PCC8801_0448
            CYH: Cyan8802_0461
            DGE: Dgeo_2155
            PMX: PERMA_1685(maeB)
            DDF: DEFDS_1074
            DAP: Dacet_1531
            CNI: Calni_1022
            HAL: VNG1624G(mdh)
            HSL: OE3308F(mdh)
            HMA: rrnAC1754(maeB)
            HWA: HQ2736A(mdh)
            NPH: NP1772A(mdh_2)
            HLA: Hlac_1525
            HUT: Huta_3014
            HMU: Hmuk_1754
            HTU: Htur_2471
            NMG: Nmag_0500
            HVO: HVO_2436(tme)
            HJE: HacjB3_09740
            HBO: Hbor_08740
            MSE: Msed_0031 Msed_1054
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.40
            IUBMB Enzyme Nomenclature: 1.1.1.40
            ExPASy - ENZYME nomenclature database: 1.1.1.40
            BRENDA, the Enzyme Database: 1.1.1.40
            CAS: 9028-47-1
///
ENTRY       EC 1.1.1.41                 Enzyme
NAME        isocitrate dehydrogenase (NAD+);
            isocitric dehydrogenase;
            beta-ketoglutaric-isocitric carboxylase;
            isocitric acid dehydrogenase;
            NAD dependent isocitrate dehydrogenase;
            NAD isocitrate dehydrogenase;
            NAD-linked isocitrate dehydrogenase;
            NAD-specific isocitrate dehydrogenase;
            NAD isocitric dehydrogenase;
            isocitrate dehydrogenase (NAD);
            IDH (ambiguous);
            nicotinamide adenine dinucleotide isocitrate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     isocitrate:NAD+ oxidoreductase (decarboxylating)
REACTION    isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH [RN:R00709]
ALL_REAC    R00709
SUBSTRATE   isocitrate [CPD:C00311];
            NAD+ [CPD:C00003]
PRODUCT     2-oxoglutarate [CPD:C00026];
            CO2 [CPD:C00011];
            NADH [CPD:C00004]
COMMENT     Requires Mn2+ or Mg2+ for activity. Unlike EC 1.1.1.42, isocitrate
            dehydrogenase (NADP+), oxalosuccinate cannot be used as a substrate.
            In eukaryotes, isocitrate dehydrogenase exists in two forms: an
            NAD+-linked enzyme found only in mitochondria and displaying
            allosteric properties, and a non-allosteric, NADP+-linked enzyme
            that is found in both mitochondria and cytoplasm [7]. The enzyme
            from some species can also use NADP+ but much more slowly [9].
REFERENCE   1  [PMID:14063317]
  AUTHORS   HATHAWAY JA, ATKINSON DE.
  TITLE     THE EFFECT OF ADENYLIC ACID ON YEAST NICOTINAMIDE ADENINE
            DINUCLEOTIDE ISOCITRATE DEHYDROGENASE, A POSSIBLE METABOLIC CONTROL
            MECHANISM.
  JOURNAL   J. Biol. Chem. 238 (1963) 2875-81.
  ORGANISM  Acetobacter peroxydans
REFERENCE   2  [PMID:14832224]
  AUTHORS   KORNBERG A, PRICER WE Jr.
  TITLE     Di- and triphosphopyridine nucleotide isocitric dehydrogenases in
            yeast.
  JOURNAL   J. Biol. Chem. 189 (1951) 123-36.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
REFERENCE   3
  AUTHORS   Plaut, G.W.E.
  TITLE     Isocitrate dehydrogenases.
  JOURNAL   In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
            ed., vol. 7, Academic Press, New York, 1963, p. 105-126.
REFERENCE   4  [PMID:13152105]
  AUTHORS   PLAUT GW, SUNG SC.
  TITLE     Diphosphopyridine nucleotide isocitric dehydrogenase from animal
            tissues.
  JOURNAL   J. Biol. Chem. 207 (1954) 305-14.
  ORGANISM  Cavia porcellus
REFERENCE   5
  AUTHORS   Ramakrishnan, C.V. and Martin, S.M.
  TITLE     Isocitric dehydrogenase in Aspergillus niger.
  JOURNAL   Arch. Biochem. Biophys. 55 (1955) 403-407.
REFERENCE   6  [PMID:13925783]
  AUTHORS   VICKERY HB.
  TITLE     A suggested new nomenclature for the isomers of isocitric acid.
  JOURNAL   J. Biol. Chem. 237 (1962) 1739-41.
REFERENCE   7  [PMID:8593959]
  AUTHORS   Camacho ML, Brown RA, Bonete MJ, Danson MJ, Hough DW.
  TITLE     Isocitrate dehydrogenases from Haloferax volcanii and Sulfolobus
            solfataricus: enzyme purification, characterisation and N-terminal
            sequence.
  JOURNAL   FEMS. Microbiol. Lett. 134 (1995) 85-90.
  ORGANISM  Sulfolobus solfataricus [GN:sso], Haloferax volcanii
REFERENCE   8  [PMID:10601238]
  AUTHORS   Kim YO, Koh HJ, Kim SH, Jo SH, Huh JW, Jeong KS, Lee IJ, Song BJ,
            Huh TL.
  TITLE     Identification and functional characterization of a novel,
            tissue-specific NAD(+)-dependent isocitrate dehydrogenase beta
            subunit isoform.
  JOURNAL   J. Biol. Chem. 274 (1999) 36866-75.
  ORGANISM  Homo sapiens [GN:hsa]
REFERENCE   9  [PMID:12204383]
  AUTHORS   Inoue H, Tamura T, Ehara N, Nishito A, Nakayama Y, Maekawa M, Imada
            K, Tanaka H, Inagaki K.
  TITLE     Biochemical and molecular characterization of the NAD(+)-dependent
            isocitrate dehydrogenase from the chemolithotroph Acidithiobacillus
            thiooxidans.
  JOURNAL   FEMS. Microbiol. Lett. 214 (2002) 127-32.
  ORGANISM  Acidithiobacillus thiooxidans
PATHWAY     ec00020  Citrate cycle (TCA cycle)
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00030  isocitrate dehydrogenase (NAD+)
GENES       HSA: 3419(IDH3A) 3420(IDH3B) 3421(IDH3G)
            PTR: 453565(IDH3A) 458048(IDH3B)
            PON: 100172089(IDH3A) 100172344(IDH3B) 100436005(IDH3G)
            MCC: 677715(IDH3A) 698558(IDH3G) 716726
            MMU: 15929(Idh3g) 170718(Idh3b) 67834(Idh3a)
            RNO: 114096(Idh3a) 25179(Idh3g) 94173(Idh3B)
            CFA: 477177(IDH3B) 479066(IDH3A) 481081(IDH3G)
            AML: 100466084 100482520 100483295
            BTA: 282446(IDH3A) 613338(IDH3B) 614145(IDH3G)
            SSC: 100152633(AFF2) 100157242(IDH3A) 100525850 733641(IDH3B)
            ECB: 100052969 100057896 100060114
            MDO: 100012825 100027983
            OAA: 100080286 100082669
            GGA: 415362(IDH3A) 426573(IDH3B)
            TGU: 100190682 100224627
            XLA: 443821(idh3b) 444419(idh3a) 444551(idh3g)
            XTR: 100144949(idh3b) 394979(idh3a) 594985(idh3g)
            DRE: 393926(idh3a) 415247(idh3b) 550579(wu:fc88f06)
            BFO: BRAFLDRAFT_124233 BRAFLDRAFT_280706
            CIN: 100177499 100181307 100186950
            SPU: 578131 587700
            DME: Dmel_CG12233(l(1)G0156) Dmel_CG32026 Dmel_CG3483 Dmel_CG5028
                 Dmel_CG6439
            DPO: Dpse_GA11495 Dpse_GA16620 Dpse_GA17474 Dpse_GA18606
                 Dpse_GA19594
            DAN: Dana_GF16768 Dana_GF16953 Dana_GF20487
            DER: Dere_GG11421 Dere_GG12546 Dere_GG18052
            DPE: Dper_GL14780 Dper_GL21529 Dper_GL23725
            DSE: Dsec_GM10262 Dsec_GM22739 Dsec_GM23677
            DSI: Dsim_GD15579 Dsim_GD18486 Dsim_GD21232
            DWI: Dwil_GK12856 Dwil_GK13007 Dwil_GK25509
            DYA: Dyak_GE23616 Dyak_GE24066
            DGR: Dgri_GH17867 Dgri_GH18988 Dgri_GH19869
            DMO: Dmoj_GI16435 Dmoj_GI22037 Dmoj_GI22415
            DVI: Dvir_GJ10975 Dvir_GJ11248 Dvir_GJ24090
            AGA: AgaP_AGAP002192 AgaP_AGAP002728 AgaP_AGAP007786
            AAG: AaeL_AAEL000454 AaeL_AAEL010143 AaeL_AAEL010814
            CQU: CpipJ_CPIJ002859 CpipJ_CPIJ009491
            AME: 409292 410396 552128
            NVI: 100115212(NV19148) 100115918(NV15997) 100123725(NV10824)
            TCA: 657626 658559 662783 662903
            API: 100161204 100162792
            PHU: Phum_PHUM417630 Phum_PHUM420870 Phum_PHUM425180
            ISC: IscW_ISCW004116 IscW_ISCW017423
            CEL: C30F12.7 C37E2.1 F35G12.2 F43G9.1
            CBR: CBG03937 CBG12504 CBG16309 CBG18040
            BMY: Bm1_13415 Bm1_14945 Bm1_37675
            SMM: Smp_018680 Smp_056200 Smp_134590
            NVE: NEMVE_v1g173016 NEMVE_v1g245762
            HMG: 100197570 100201384 100203218 100204979
            TAD: TRIADDRAFT_54615 TRIADDRAFT_63943
            ATH: AT1G32480 AT2G17130(IDH2) AT3G09810 AT4G35260(IDH1) AT4G35650
                 AT5G03290
            POP: POPTR_558763 POPTR_589452 POPTR_819931 POPTR_825258
                 POPTR_827247 POPTR_832930
            RCU: RCOM_0519460 RCOM_1355470
            VVI: 100245625 100253697 100263635
            OSA: 4324442 4329858 4336169
            SBI: SORBI_03g011050 SORBI_04g024840
            ZMA: 100191841 100272953 100274026 100283574
            PPP: PHYPADRAFT_129687 PHYPADRAFT_133156 PHYPADRAFT_144112
                 PHYPADRAFT_185348 PHYPADRAFT_193492 PHYPADRAFT_59205
            CRE: CHLREDRAFT_196042(IDH1) CHLREDRAFT_196044(IDH2)
            VCN: VOLCADRAFT_104752(idh2)
            CME: CMS272C CMT412C
            SCE: YNL037C(IDH1) YOR136W(IDH2)
            AGO: AGOS_ADL223W AGOS_AFR137C
            KLA: KLLA0E03125g KLLA0F04103g
            LTH: KLTH0F15048g KLTH0G10186g
            PPA: PAS_chr2-1_0120 PAS_chr4_0580
            VPO: Kpol_1039p35 Kpol_440p12 Kpol_543p8
            ZRO: ZYRO0D02838g ZYRO0D11220g
            CGR: CAGL0G02673g CAGL0I07227g
            DHA: DEHA2C10758g DEHA2G05786g
            PIC: PICST_42313(IDH2) PICST_91057(IDH1)
            PGU: PGUG_02910 PGUG_03146
            LEL: LELG_00480 LELG_01294
            CAL: CaO19.12289(IDH1) CaO19.13213(IDH2) CaO19.4826(IDH1)
                 CaO19.5791(IDH2)
            CTP: CTRG_01317 CTRG_03395
            CDU: CD36_09070 CD36_17850
            YLI: YALI0D06303g YALI0E05137g
            CLU: CLUG_05434 CLUG_05795
            NCR: NCU00775 NCU07697
            PAN: PODANSg09844 PODANSg7259
            MGR: MGG_01712(MG01712.4) MGG_01995(MG01995.4)
            FGR: FG05733.1 FG09580.1
            SSL: SS1G_04160 SS1G_09958
            BFU: BC1G_00206 BC1G_07285
            ANI: AN1003.2 AN5790.2
            AFM: AFUA_1G12800 AFUA_6G06370
            NFI: NFIA_012760 NFIA_052000
            AOR: AO090003000008 AO090012000629
            ANG: An08g05580 An18g06760
            AFV: AFLA_018850 AFLA_037910
            ACT: ACLA_022670 ACLA_088150
            PCS: Pc13g11380 Pc14g01170
            CIM: CIMG_06836 CIMG_07263
            CPW: CPC735_000710 CPC735_032440
            URE: UREG_03641 UREG_07827
            PNO: SNOG_03647 SNOG_06082
            TML: GSTUM_00004106001 GSTUM_00009134001
            SPO: SPAC11G7.03(idh1) SPBC902.05c(idh2)
            CNE: CNA04610 CNJ02060
            CNB: CNBA4420 CNBJ1400
            LBC: LACBIDRAFT_311842 LACBIDRAFT_311861
            CCI: CC1G_00350 CC1G_00372
            SCM: SCHCODRAFT_48000 SCHCODRAFT_80265
            UMA: UM01328.1 UM01329.1
            MGL: MGL_0301 MGL_0302
            MBR: MONBRDRAFT_19354 MONBRDRAFT_37916 MONBRDRAFT_6048
            DDI: DDB_G0271344(idhA) DDB_G0293872(idhB)
            TET: TTHERM_00344030 TTHERM_00723390
            PTM: GSPATT00012691001 GSPATT00013309001 GSPATT00017313001
                 GSPATT00023050001 GSPATT00025896001
            XFA: XF2596
            XFT: PD1973
            XFM: Xfasm12_2166
            XFN: XfasM23_2077
            XCC: XCC0967(icd)
            XCB: XC_3268
            XCA: xccb100_3384(icd1)
            XCV: XCV1076
            XAC: XAC1046(icd)
            XOO: XOO1024(icd)
            XOM: XOO_0926
            XOP: PXO_02485
            XAL: XALc_0579
            SML: Smlt0982
            SMT: Smal_0828
            SON: SO_1538
            SDN: Sden_2561
            SFR: Sfri_2779
            SAZ: Sama_2423
            SBL: Sbal_1368
            SBM: Shew185_1354
            SBN: Sbal195_1393
            SBP: Sbal223_2992
            SLO: Shew_2760
            SPC: Sputcn32_1286
            SSE: Ssed_3318
            SPL: Spea_2980
            SHE: Shewmr4_2720
            SHM: Shewmr7_2791
            SHN: Shewana3_2890
            SHW: Sputw3181_2820
            SHL: Shal_3069
            SWD: Swoo_3466
            SWP: swp_3606
            SVO: SVI_1132
            ILO: IL0861
            CPS: CPS_3540
            PHA: PSHAb0465
            PAT: Patl_3197
            AMC: MADE_03050
            FBL: Fbal_2814
            MCA: MCA3071
            AEH: Mlg_0664
            CSA: Csal_1434
            ABO: ABO_0296(icd)
            AHA: AHA_1152
            ASA: ASA_3183
            REH: H16_B1016(icd3)
            BXE: Bxe_C0665
            RFR: Rfer_2380 Rfer_2411
            VAP: Vapar_4079
            HAR: HEAR3270
            MMS: mma_3499(idh)
            LCH: Lcho_4250
            TIN: Tint_2512
            BBA: Bd1264(leuB)
            DPS: DP0778
            MXA: MXAN_6337
            SCL: sce5773(icd1) sce6432(leuB2)
            HOH: Hoch_0287
            SAT: SYN_01410
            MET: M446_0777
            GBE: GbCGDNIH1_2050
            GDI: GDI_1991
            GDJ: Gdia_0214
            APT: APA01_10420
            BHA: BH3159(citC)
            BCE: BC4593
            BCA: BCE_4724(citC)
            BCZ: BCZK4334(citC)
            BTK: BT9727_4322(citC)
            BTL: BALH_4177(citC)
            BCL: ABC2714(citC)
            OIH: OB2167(citC)
            GKA: GK2735
            GTN: GTNG_2659
            SAH: SaurJH1_1785
            SAJ: SaurJH9_1751
            SAS: SAS1622
            SAR: SAR1773(citC)
            SAC: SACOL1741(icd)
            SAA: SAUSA300_1640(icd)
            SAO: SAOUHSC_01801
            SAE: NWMN_1587(citC)
            SAB: SAB1553c(citC)
            SER: SERP1257(icd)
            LWE: lwe1579(citC)
            CAC: CA_C0972(citC)
            CNO: NT01CX_0139
            CDF: CD0834
            CDC: CD196_0783
            CDL: CDR20291_0764
            CBO: CBO0419
            CBA: CLB_0452
            CBH: CLC_0485
            CBY: CLM_0498
            CBL: CLK_3621
            CBB: CLD_0324
            CBI: CLJ_B0487
            CBF: CLI_0504
            CLJ: CLJU_c06630
            CCB: Clocel_2469
            AMT: Amet_1319
            PTH: PTH_2517(leuB)
            DAU: Daud_1038
            APR: Apre_1101
            CHY: CHY_1107
            MTA: Moth_0993
            ADG: Adeg_1102
            CSC: Csac_0751
            ATE: Athe_0525
            COB: COB47_0470
            HOR: Hore_08060
            HAS: Halsa_2046
            AAR: Acear_2053
            RXY: Rxyl_1297
            CCU: Ccur_02380
            ELE: Elen_2334
            LIL: LA_4067(icd)
            LBJ: LBJ_0210(icdA)
            ABA: Acid345_4042
            ACA: ACP_1462
            SUS: Acid_7350
            SRU: SRU_1677
            SRM: SRM_01881(icd)
            LBA: Lebu_1446
            STR: Sterm_2154
            IPO: Ilyop_0225
            GAU: GAU_2477(icd)
            PSL: Psta_0983
            PLM: Plim_0079
            EMI: Emin_0404
            ACO: Amico_1301
            SYW: SYNW0166(icd)
            SYG: sync_0214(icd)
            CYA: CYA_1467
            CYB: CYB_1678
            TEL: tlr0302
            GVI: gvip428(icd)
            PMA: Pro1752(icd)
            PMM: PMM1596(icd)
            PMT: PMT1935(icd)
            PMB: A9601_18051(icd)
            PMC: P9515_17831(icd)
            PMF: P9303_25761(icd)
            PMG: P9301_17881(icd)
            PME: NATL1_20451(icd)
            AMR: AM1_5753(icd)
            CTS: Ctha_2161
            DET: DET0450
            DEH: cbdb_A408
            DEB: DehaBAV1_0427
            DEV: DhcVS_392
            DEG: DehalGT_0391
            DLY: Dehly_0358
            HAU: Haur_1453
            STI: Sthe_1662
            TPT: Tpet_1602
            PMO: Pmob_1706
            TYE: THEYE_A1278
            TTR: Tter_0788
            MTP: Mthe_0549
            ABI: Aboo_1463
            IAG: Igag_1773
            KCR: Kcr_0970
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.41
            IUBMB Enzyme Nomenclature: 1.1.1.41
            ExPASy - ENZYME nomenclature database: 1.1.1.41
            BRENDA, the Enzyme Database: 1.1.1.41
            CAS: 9001-58-5
///
ENTRY       EC 1.1.1.42                 Enzyme
NAME        isocitrate dehydrogenase (NADP+);
            oxalosuccinate decarboxylase;
            oxalsuccinic decarboxylase;
            isocitrate (NADP) dehydrogenase;
            isocitrate (nicotinamide adenine dinucleotide phosphate)
            dehydrogenase;
            NADP-specific isocitrate dehydrogenase;
            NADP-linked isocitrate dehydrogenase;
            NADP-dependent isocitrate dehydrogenase;
            NADP isocitric dehydrogenase;
            isocitrate dehydrogenase (NADP-dependent);
            NADP-dependent isocitric dehydrogenase;
            triphosphopyridine nucleotide-linked isocitrate
            dehydrogenase-oxalosuccinate carboxylase;
            NADP+-linked isocitrate dehydrogenase;
            IDH (ambiguous);
            dual-cofactor-specific isocitrate dehydrogenase;
            NADP+-ICDH;
            NADP+-IDH;
            IDP;
            IDP1;
            IDP2;
            IDP3
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     isocitrate:NADP+ oxidoreductase (decarboxylating)
REACTION    (1) isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+ (overall
            reaction) [RN:R00267];
            (2) (1a) isocitrate + NADP+ = oxalosuccinate + NADPH + H+
            [RN:R01899];
            (3) (1b) oxalosuccinate = 2-oxoglutarate + CO2 [RN:R00268]
ALL_REAC    R00267 R00268 R01899
SUBSTRATE   isocitrate [CPD:C00311];
            NADP+ [CPD:C00006];
            oxalosuccinate [CPD:C05379]
PRODUCT     2-oxoglutarate [CPD:C00026];
            CO2 [CPD:C00011];
            NADPH [CPD:C00005];
            H+ [CPD:C00080];
            oxalosuccinate [CPD:C05379]
COMMENT     Requires Mn2+ or Mg2+ for activity. Unlike EC 1.1.1.41, isocitrate
            dehydrogenase (NAD+), oxalosuccinate can be used as a substrate. In
            eukaryotes, isocitrate dehydrogenase exists in two forms: an
            NAD+-linked enzyme found only in mitochondria and displaying
            allosteric properties, and a non-allosteric, NADP+-linked enzyme
            that is found in both mitochondria and cytoplasm [6]. The enzyme
            from some species can also use NAD+ but much more slowly [6,7].
REFERENCE   1  [PMID:13363868]
  AUTHORS   AGOSIN M, WEINBACH EC.
  TITLE     Partial purification and characterization of the isocitric
            dehydrogenase from Trypanosoma cruzi.
  JOURNAL   Biochim. Biophys. Acta. 21 (1956) 117-26.
  ORGANISM  Trypanosoma cruzi [GN:tcr]
REFERENCE   2  [PMID:13355848]
  AUTHORS   DIXON M, MOYLE J.
  TITLE     Purification of the isocitric enzyme (triphosphopyridine
            nucleotide-linked isocitric dehydrogenase-oxalosuccinic
            carboxylase).
  JOURNAL   Biochem. J. 63 (1956) 548-52.
  ORGANISM  Sus scofa [GN:ssc]
REFERENCE   3
  AUTHORS   Plaut, G.W.E.
  TITLE     Isocitrate dehydrogenases.
  JOURNAL   In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
            ed., vol. 7, Academic Press, New York, 1963, p. 105-126.
REFERENCE   4  [PMID:13438885]
  AUTHORS   SIEBERT G, DUBUC J, WARNER RC, PLAUT GW.
  TITLE     The preparation of isocitric dehydrogenase from mammalian heart.
  JOURNAL   J. Biol. Chem. 226 (1957) 965-75.
  ORGANISM  Sus scofa [GN:ssc]
REFERENCE   5  [PMID:13925783]
  AUTHORS   VICKERY HB.
  TITLE     A suggested new nomenclature for the isomers of isocitric acid.
  JOURNAL   J. Biol. Chem. 237 (1962) 1739-41.
REFERENCE   6  [PMID:8593959]
  AUTHORS   Camacho ML, Brown RA, Bonete MJ, Danson MJ, Hough DW.
  TITLE     Isocitrate dehydrogenases from Haloferax volcanii and Sulfolobus
            solfataricus: enzyme purification, characterisation and N-terminal
            sequence.
  JOURNAL   FEMS. Microbiol. Lett. 134 (1995) 85-90.
  ORGANISM  Sulfolobus solfataricus [GN:sso], Haloferax volcanii
REFERENCE   7  [PMID:9325430]
  AUTHORS   Steen IH, Lien T, Birkeland NK.
  TITLE     Biochemical and phylogenetic characterization of isocitrate
            dehydrogenase from a hyperthermophilic archaeon, Archaeoglobus
            fulgidus.
  JOURNAL   Arch. Microbiol. 168 (1997) 412-20.
  ORGANISM  Archaeoglobus fulgidus [GN:afu]
REFERENCE   8  [PMID:15254034]
  AUTHORS   Koh HJ, Lee SM, Son BG, Lee SH, Ryoo ZY, Chang KT, Park JW, Park DC,
            Song BJ, Veech RL, Song H, Huh TL.
  TITLE     Cytosolic NADP+-dependent isocitrate dehydrogenase plays a key role
            in lipid metabolism.
  JOURNAL   J. Biol. Chem. 279 (2004) 39968-74.
  ORGANISM  Rattus norvegicus [GN:rno]
REFERENCE   9  [PMID:12207025]
  AUTHORS   Ceccarelli C, Grodsky NB, Ariyaratne N, Colman RF, Bahnson BJ.
  TITLE     Crystal structure of porcine mitochondrial NADP+-dependent
            isocitrate dehydrogenase complexed with Mn2+ and isocitrate.
            Insights into the enzyme mechanism.
  JOURNAL   J. Biol. Chem. 277 (2002) 43454-62.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00020  Citrate cycle (TCA cycle)
            ec00480  Glutathione metabolism
            ec00720  Carbon fixation in prokaryotes
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00031  isocitrate dehydrogenase
GENES       HSA: 3417(IDH1) 3418(IDH2)
            PTR: 453645(IDH2) 460113(IDH1)
            PON: 100171634(IDH1) 100441867(IDH2)
            MCC: 701480(IDH2) 710019(IDH1)
            MMU: 15926(Idh1) 269951(Idh2)
            RNO: 24479(Idh1) 361596(Idh2)
            CFA: 478889(IDH1) 479043(IDH2)
            AML: 100478074 100480163
            BTA: 281235(IDH1) 327669(IDH2)
            SSC: 100155880(IDH2) 397603(IDH2)
            ECB: 100066416(IDH1) 100069086
            MDO: 100015156 751083(IDH1)
            OAA: 100076051(IDH2) 100080086
            GGA: 424112(IDH1) 431056
            XLA: 380013(idh2) 494713(idh1)
            XTR: 448026(idh2) 448164(idh1)
            DRE: 100006589(idh1) 386951(idh2)
            BFO: BRAFLDRAFT_115608 BRAFLDRAFT_118551
            CIN: 100175603 100184016
            SPU: 580429 581147
            DME: Dmel_CG7176(Idh)
            DPO: Dpse_GA20156
            DAN: Dana_GF10112
            DER: Dere_GG15087
            DPE: Dper_GL24577
            DSE: Dsec_GM24945
            DSI: Dsim_GD12997
            DWI: Dwil_GK18037
            DYA: Dyak_GE21312
            DGR: Dgri_GH16411
            DMO: Dmoj_GI12492
            DVI: Dvir_GJ12396
            AGA: AgaP_AGAP003168 AgaP_AGAP006660
            AAG: AaeL_AAEL000746 AaeL_AAEL012614
            CQU: CpipJ_CPIJ000337 CpipJ_CPIJ003304
            AME: 551276(Idh)
            NVI: 100122999(NV11525)
            TCA: 657289 659013 661014
            API: 100159933 100167396
            PHU: Phum_PHUM098590 Phum_PHUM450200
            ISC: IscW_ISCW001977 IscW_ISCW003975
            CEL: C34F6.8 F59B8.2
            CBR: CBG17397 CBG21657
            BMY: Bm1_48935
            SMM: Smp_163050
            NVE: NEMVE_v1g185113 NEMVE_v1g205753 NEMVE_v1g226098
            HMG: 100208927
            TAD: TRIADDRAFT_23270 TRIADDRAFT_35221
            ATH: AT1G54340(ICDH) AT1G65930 AT5G14590
            POP: POPTR_648243 POPTR_770098 POPTR_797853 POPTR_803363
            RCU: RCOM_0113200 RCOM_0988350 RCOM_1095740
            VVI: 100243260 100249290 100261578
            OSA: 4324176 4327213 4336353 4339674
            SBI: SORBI_06g022050
            ZMA: 100191657 100217128 100272371(idh2) 100274592(gpm541)
            PPP: PHYPADRAFT_222920 PHYPADRAFT_93341
            CRE: CHLREDRAFT_196567(IDH3)
            VCN: VOLCADRAFT_77629(idh3)
            OLU: OSTLU_47417
            CME: CMT216C
            SCE: YDL066W(IDP1) YLR174W(IDP2) YNL009W(IDP3)
            AGO: AGOS_AAL022W AGOS_AER061C
            KLA: KLLA0B03355g KLLA0F12342g
            LTH: KLTH0D14476g KLTH0H12012g
            PPA: PAS_chr1-1_0233 PAS_chr2-1_0580
            VPO: Kpol_1048p70 Kpol_1055p78
            ZRO: ZYRO0B12496g ZYRO0E05016g
            CGR: CAGL0B04917g CAGL0D00770g CAGL0H03663g
            PIC: PICST_43870(IDP2) PICST_72104(IDP1)
            PGU: PGUG_02805 PGUG_03659
            LEL: LELG_00093 LELG_00976
            CAL: CaO19.12678(IDP1) CaO19.3733(IDP2) CaO19.5211(IDP1)
            CTP: CTRG_00909 CTRG_01521
            CDU: CD36_20310 CD36_27320
            YLI: YALI0F04095g
            CLU: CLUG_01682 CLUG_02078
            NCR: NCU03857
            PAN: PODANSg976
            MGR: MGG_07268(MG07268.4)
            FGR: FG10347.1
            SSL: SS1G_04924
            BFU: BC1G_14721
            ANI: AN2999.2
            AFM: AFUA_3G08660
            NFI: NFIA_068460
            AOR: AO090005001404
            ANG: An02g12430(icdA)
            AFV: AFLA_086400
            ACT: ACLA_036650
            PCS: Pc20g03610
            CIM: CIMG_07673
            CPW: CPC735_042850
            URE: UREG_07614
            PNO: SNOG_01446
            TML: GSTUM_00011853001
            SPO: SPAC6G10.08(idp1)
            CNE: CNB04090
            CNB: CNBB1650
            LBC: LACBIDRAFT_317084
            CCI: CC1G_11465
            SCM: SCHCODRAFT_83125
            UMA: UM06111.1
            MGL: MGL_1821
            MBR: MONBRDRAFT_31232
            NGR: NAEGRDRAFT_82731
            DDI: DDB_G0272208(idhC) DDB_G0272210(idhM)
            PFA: PF13_0242
            PFD: PFDG_02772
            PFH: PFHG_02400
            PYO: PY00592 PY02505
            PCB: PC000412.00.0
            PBE: PB000917.03.0
            PKN: PKH_120870
            PVX: PVX_083185
            TAN: TA10850
            TPV: TP04_0620
            BBO: BBOV_III007260(17.m07637)
            TGO: TGME49_066760 TGME49_113140
            TET: TTHERM_00196200 TTHERM_00794110
            PTM: GSPATT00005218001 GSPATT00009194001 GSPATT00020509001
                 GSPATT00022820001 GSPATT00027349001 GSPATT00029781001
            TBR: Tb11.03.0230 Tb927.8.3690
            TCR: 506925.319 511575.60
            LMA: LmjF10.0290 LmjF33.2550
            LIF: LinJ10.0610 LinJ33.2340
            LBZ: LbrM10_V2.0310 LbrM33_V2.2820
            PIF: PITG_07056 PITG_23158
            ECO: b1136(icd)
            ECJ: JW1122(icd)
            ECD: ECDH10B_1208(icd)
            EBW: BWG_0984(icd)
            ECE: Z1865(icdA)
            ECS: ECs1608
            ECF: ECH74115_1598(icd)
            ETW: ECSP_1516(icd)
            EOJ: ECO26_1670(icd)
            EOI: ECO111_1484(icd)
            EOH: ECO103_1260(icd)
            ECG: E2348C_1277(icd)
            EOK: G2583_1412(icd)
            ECC: c1517(icdA)
            ECP: ECP_1131
            ECI: UTI89_C1266(icdA)
            ECV: APECO1_218
            ECX: EcHS_A1256(icd)
            ECW: EcE24377A_1299(icd)
            ECM: EcSMS35_1989(icd)
            ECY: ECSE_1202
            ECR: ECIAI1_1174(icd)
            ECQ: ECED1_1280(icd)
            ECK: EC55989_1249(icd)
            ECT: ECIAI39_1995(icd)
            EUM: ECUMN_1380(icd)
            ECZ: ECS88_1151(icd)
            ECL: EcolC_2467
            EBR: ECB_01134(icdA)
            EBD: ECBD_2463
            EFE: EFER_1794(icd)
            STY: STY1278(icdA)
            STT: t1682(icdA)
            STM: STM1238(icdA)
            SPT: SPA1612(icdA)
            SEK: SSPA1497
            SPQ: SPAB_02276
            SEI: SPC_2506(icdA)
            SEC: SC1189(icdA)
            SEH: SeHA_C1355(icd)
            SEE: SNSL254_A1339(icd)
            SEW: SeSA_A1317(icd)
            SEA: SeAg_B1946(icd)
            SED: SeD_A2128(icd)
            SEG: SG1883(icdA)
            SET: SEN1811(icdA)
            SES: SARI_01752
            YPE: YPO1641(icdA)
            YPK: y1802(icdA)
            YPA: YPA_1883
            YPN: YPN_1990
            YPM: YP_1771(icdA)
            YPP: YPDSF_1807
            YPG: YpAngola_A2848(icd)
            YPZ: YPZ3_2051(icdA)
            YPS: YPTB2427(icdA)
            YPI: YpsIP31758_1615(icd)
            YPY: YPK_1723
            YPB: YPTS_2510
            YEN: YE1725(icd)
            SFL: SF1155(icdA)
            SFX: S1238(icdA)
            SFV: SFV_1171(icdA)
            SSN: SSON_1154(icdA)
            SBO: SBO_1903(icdA)
            SBC: SbBS512_E1315(icd)
            SDY: SDY_2016(icdA)
            ECA: ECA2439(icd)
            PCT: PC1_1872
            PWA: Pecwa_2157
            ETA: ETA_19490(icd)
            EPY: EpC_20880(icd)
            EAM: EAMY_1537(icdA)
            EAY: EAM_1520(icdA)
            EBI: EbC_16940(icd)
            PLU: plu2801(icd)
            PAY: PAU_01740(icdA)
            SGL: SG0700
            ENT: Ent638_1649
            ENC: ECL_02498
            ESC: Entcl_2658
            ESA: ESA_02209
            CTU: Ctu_17140(icd)
            KPN: KPN_01144(icdA)
            KPE: KPK_3407(icd)
            KPU: KP1_2146(icdA)
            KVA: Kvar_3235
            CKO: CKO_01835
            CRO: ROD_12261(icd)
            SPE: Spro_2025
            PMR: PMI0891(icd)
            EIC: NT01EI_2315
            ETR: ETAE_2050
            HDE: HDEF_2304(icdA)
            DDA: Dd703_2060
            DDC: Dd586_1934
            DDD: Dda3937_02082(icd)
            DZE: Dd1591_1945
            XBO: XBJ1_2828(icd)
            XNE: XNC1_2703(icd)
            PAM: PANA_1518(icd)
            PVA: Pvag_0940(icdA)
            PAO: Pat9b_1523
            HAP: HAPS_2276(icd)
            HSO: HS_1641(icd)
            HSM: HSM_1803
            PMU: PM1606(idp)
            MSU: MS2370(icd)
            XFA: XF2700
            XFT: PD2056(icd)
            XFM: Xfasm12_2249
            XFN: XfasM23_2159
            XCC: XCC3782(icd)
            XCB: XC_3854
            XCA: xccb100_3965(icd2)
            XCV: XCV3960(icd)
            XAC: XAC3835(icd)
            XOO: XOO4167(icd)
            XOM: XOO_3943
            XOP: PXO_03994
            XAL: XALc_2883 XALc_3137
            SML: Smlt4273(icd)
            SMT: Smal_3684
            PSU: Psesu_3064
            VCH: VC1141
            VCO: VC0395_A0711(icd)
            VCM: VCM66_1097(icd)
            VCJ: VCD_003201
            VVU: VV1_2118
            VVY: VV2325
            VVM: VVM_01942
            VPA: VP1011
            VHA: VIBHAR_01563
            VSP: VS_1071
            VEX: VEA_003959
            VFI: VF_1775
            VFM: VFMJ11_1902
            VSA: VSAL_I2205(icd)
            PPR: PBPRA1149
            PAE: PA2623(icd) PA2624(idh)
            PAU: PA14_30180(idh) PA14_30190(icd)
            PAP: PSPA7_2583 PSPA7_2584(icd)
            PAG: PLES_24811(idh) PLES_24821(icd)
            PPU: PP_4011(icd) PP_4012
            PPF: Pput_1821 Pput_1822
            PPG: PputGB1_3616 PputGB1_3617
            PPW: PputW619_3415 PputW619_3416
            PST: PSPTO_3356
            PSB: Psyr_3186
            PSP: PSPPH_3100
            PFL: PFL_3888(icd) PFL_3889
            PFO: Pfl01_3593 Pfl01_3594
            PFS: PFLU3808 PFLU3809
            PEN: PSEEN2202(idh) PSEEN2204(icd)
            PMY: Pmen_2396 Pmen_2397
            PSA: PST_2301(icd) PST_2302(idh)
            CJA: CJA_2571
            AVN: Avin_28310(icd)
            PAR: Psyc_0287(icd2)
            PCR: Pcryo_0314 Pcryo_0315
            PRW: PsycPRwf_2086 PsycPRwf_2087
            ACI: ACIAD1187(idh) ACIAD1190(icd)
            ACD: AOLE_04755 AOLE_04765
            ACB: A1S_2475 A1S_2477
            ABM: ABSDF0995(idh)
            ABY: ABAYE0980(idh) ABAYE0982(icd)
            ABC: ACICU_02687 ACICU_02689
            ABN: AB57_2919(icd) AB57_2921
            ABB: ABBFA_000966 ABBFA_000968(icd)
            MCT: MCR_0327(icd)
            SON: SO_2629(icd)
            SDN: Sden_1831
            SFR: Sfri_2257
            SAZ: Sama_2059
            SBL: Sbal_2475
            SBM: Shew185_2468
            SBN: Sbal195_2588
            SBP: Sbal223_1876
            SLO: Shew_1563
            SPC: Sputcn32_2230
            SSE: Ssed_1883
            SPL: Spea_2535
            SHE: Shewmr4_1606
            SHM: Shewmr7_1681
            SHN: Shewana3_1750 Shewana3_2424
            SHW: Sputw3181_1779
            SHL: Shal_1718
            SWD: Swoo_2702
            SWP: swp_1868
            SVO: SVI_1824(icd)
            ILO: IL1433
            CPS: CPS_1354 CPS_2896(icd) CPS_2897
            PHA: PSHAa1303(icd) PSHAa1727
            PAT: Patl_2377
            PSM: PSM_A1311 PSM_A1689(icd)
            SDE: Sde_1684
            MAQ: Maqu_0090
            AMC: MADE_02366
            PIN: Ping_0983
            TTU: TERTU_1960
            FBL: Fbal_1990 Fbal_1991
            CBU: CBU_1200(icd)
            CBS: COXBURSA331_A1349(icd)
            CBD: CBUD_1288(icd)
            CBG: CbuG_0809(icd)
            CBC: CbuK_1064(icd)
            LPN: lpg0816(icd)
            LPF: lpl0849(icd)
            LPP: lpp0878(icd)
            LPC: LPC_2479(icd)
            LPA: lpa_01245(icd)
            LLO: LLO_2043(icd)
            FTU: FTT_1526c(idh)
            FTF: FTF1526c(idh)
            FTW: FTW_0405(icd)
            FTL: FTL_0588
            FTH: FTH_0588
            FTA: FTA_0622
            FTM: FTM_0372(icd)
            FTN: FTN_1434(icd)
            FPH: Fphi_1241
            TCX: Tcr_1101
            NOC: Noc_1378
            NHL: Nhal_2539
            NWA: Nwat_1248
            ALV: Alvin_2218
            AEH: Mlg_0262 Mlg_1121
            HHA: Hhal_2290
            TGR: Tgr7_1840
            TKM: TK90_1264
            HNA: Hneap_0618
            HCH: HCH_02336(icd) HCH_03212
            CSA: Csal_0525
            HEL: HELO_3063(icd)
            ABO: ABO_1281(icd) ABO_1282(icdA)
            KKO: Kkor_1100
            MMW: Mmwyl1_3267
            AHA: AHA_1436(icd)
            ASA: ASA_2942(icd)
            TAU: Tola_2323
            AFE: Lferr_0586
            AFR: AFE_0424(icd)
            RMA: Rmag_0423
            VOK: COSY_0392(icd)
            GPB: HDN1F_15670(icd)
            NMA: NMA1116
            NME: NMB0920(icd)
            NMC: NMC0897(icd)
            NMN: NMCC_0861(icd)
            NMI: NMO_0815(icd)
            NGO: NGO1082
            NGK: NGK_0685
            NLA: NLA_13420(icd)
            CVI: CV_3664
            LHK: LHK_00368(icd1)
            RSO: RSc2490(icd)
            RSC: RCFBP_10910(icd)
            RSL: RPSI07_0976(icd)
            RPI: Rpic_2752
            RPF: Rpic12D_2349
            REU: Reut_A2756 Reut_B4201
            REH: H16_A3056(icd1) H16_B1931(icd2)
            RME: Rmet_2895 Rmet_3729(icdA)
            CTI: RALTA_A2531(icd) RALTA_B1630(icd)
            BMA: BMA0486(icd)
            BMV: BMASAVP1_A0683(icd)
            BML: BMA10229_A1015(icd)
            BMN: BMA10247_0132(icd)
            BPS: BPSL0896(icd)
            BPM: BURPS1710b_1108(icd)
            BPL: BURPS1106A_0960(icd)
            BPD: BURPS668_0956(icd)
            BPR: GBP346_A0885(icd)
            BTE: BTH_I0759(icd)
            BVI: Bcep1808_2601 Bcep1808_2602
            BUR: Bcep18194_A5855 Bcep18194_A5856
            BCN: Bcen_1912 Bcen_1913
            BCH: Bcen2424_2523 Bcen2424_2524
            BCM: Bcenmc03_2548 Bcenmc03_2549
            BCJ: BCAL2735 BCAL2736
            BAM: Bamb_2571 Bamb_2572
            BAC: BamMC406_2442 BamMC406_2443
            BMU: Bmul_0770 Bmul_0771
            BMJ: BMULJ_02489(icd) BMULJ_02490(icd)
            BXE: Bxe_A0797 Bxe_B0532
            BPH: Bphy_0565 Bphy_5456
            BPY: Bphyt_3169 Bphyt_4080
            BGL: bglu_1g28910 bglu_1g28920
            BGE: BC1002_0850 BC1002_2409 BC1002_4714
            BRH: RBRH_00946
            PNU: Pnuc_0366
            PNE: Pnec_0369
            BPE: BP2488(icd)
            BPA: BPP3475(icd)
            BBR: BB3924(icd)
            BPT: Bpet1567(icd)
            BAV: BAV1860(icd) BAV2709(icd)
            AXY: AXYL_01184(icd1) AXYL_03079(icd2)
            TEQ: TEQUI_1024
            RFR: Rfer_2761
            POL: Bpro_2942
            PNA: Pnap_1930 Pnap_3680
            AAV: Aave_2572
            AJS: Ajs_2297 Ajs_2300
            DIA: Dtpsy_1559 Dtpsy_1562
            VEI: Veis_0624
            DAC: Daci_3645 Daci_3661
            VAP: Vapar_2649
            VPE: Varpa_1457 Varpa_3278
            CTT: CtCNB1_2811 CtCNB1_2815
            ADN: Alide_2620 Alide_2622
            MPT: Mpe_A2468
            HAR: HEAR3467(idh)
            MMS: mma_3692(icd)
            HSE: Hsero_1396(icd) Hsero_2515(icd)
            LCH: Lcho_2769 Lcho_4382
            TIN: Tint_1393
            NEU: NE1730(icd)
            NET: Neut_2045
            NMU: Nmul_A2245
            EBA: ebA829(icd) ebA832(icd2)
            AZO: azo1146(icd2) azo1147(icd1)
            DAR: Daro_3119 Daro_3120
            TMZ: Tmz1t_0171 Tmz1t_1261
            TBD: Tbd_0854
            MFA: Mfla_2139
            MMB: Mmol_0597
            MEH: M301_0605
            MEI: Msip34_0589
            MEP: MPQ_0615(icd)
            APP: CAP2UW1_0663
            SLT: Slit_0968
            GCA: Galf_2246
            HPY: HP0027
            HPJ: jhp0023(icd)
            HPA: HPAG1_0025
            HPS: HPSH_00135
            HPG: HPG27_24(icd)
            HPP: HPP12_0023(icd)
            HPB: HELPY_0025(icd)
            HPL: HPB8_1597(icd)
            HPC: HPPC_00125
            HPM: HPSJM_00155
            HHE: HH1196
            HAC: Hac_0041(icdA)
            HMS: HMU04060(icd)
            HFE: Hfelis_06280(leuB)
            WSU: WS1454
            TDN: Suden_1047
            SKU: Sulku_1464
            CJE: Cj0531(icd)
            CJR: CJE0635(icd)
            CJJ: CJJ81176_0556(icd)
            CJU: C8J_0492(icd)
            CJN: ICDCCJ_478
            CJD: JJD26997_1399(icd)
            CFF: CFF8240_0913
            CHA: CHAB381_1135
            CCO: CCC13826_1088
            ABU: Abu_1314(icd)
            ANT: Arnit_1921
            SDL: Sdel_1089
            NIS: NIS_0834
            SUN: SUN_0570
            NSA: Nitsa_0355
            NAM: NAMH_1235
            GSU: GSU1465(icd)
            GME: Gmet_1359
            GUR: Gura_2194
            GLO: Glov_1624
            GBM: Gbem_2901(icd)
            GEO: Geob_2663
            GEM: GM21_1324
            PCA: Pcar_1038(icd)
            PPD: Ppro_0452
            DVU: DVU0477(icd)
            DVL: Dvul_2464
            DVM: DvMF_1739
            DDE: Dde_3476
            DDS: Ddes_0101
            DMA: DMR_28220(icd)
            DSA: Desal_1093
            DAS: Daes_2678
            DBA: Dbac_1985
            DRT: Dret_0439
            BBA: Bd3723(icdA)
            DAK: DaAHT2_1237
            DPR: Despr_0574
            DOL: Dole_1908
            DAL: Dalk_1934
            DAT: HRM2_41030(icd)
            ADE: Adeh_1625 Adeh_2227
            ACP: A2cp1_1721 A2cp1_2323
            AFW: Anae109_1588 Anae109_2186
            ANK: AnaeK_1648 AnaeK_2235
            MXA: MXAN_3537(icd)
            SCL: sce6818(icd2)
            HOH: Hoch_1645
            SFU: Sfum_3896
            DBR: Deba_1275
            RPR: RP265
            RTY: RT0256(icd)
            RCM: A1E_01530
            RCO: RC0353(icd)
            RFE: RF_1015(icd)
            RAK: A1C_01920
            RRI: A1G_02020
            RRJ: RrIowa_0425
            RMS: RMA_0358(icd)
            RPK: RPR_02250
            RAF: RAF_ORF0327(icd)
            RBE: RBE_0289(icd)
            RBO: A1I_06360
            OTS: OTBS_0842(icd)
            OTT: OTT_1639(icd)
            WOL: WD0791
            WBM: Wbm0367
            WRI: WRi_006330
            WPI: WPa_0547
            AMA: AM1131(icd)
            AMF: AMF_855(icd)
            ACN: ACIS_00241(icd)
            APH: APH_1166
            ERU: Erum8530(icd)
            ERW: ERWE_CDS_09040(icd)
            ERG: ERGA_CDS_08940(icd)
            ECN: Ecaj_0890
            ECH: ECH_1114
            NSE: NSE_0172
            NRI: NRI_0168(icd)
            PUB: SAR11_0644(icdA)
            MLO: mll0036
            MCI: Mesci_4376
            MES: Meso_1267
            PLA: Plav_2580
            SME: SMc00480(icd)
            SMD: Smed_1519
            RHI: NGR_c16430(icd)
            ATU: Atu1870(icdA)
            ARA: Arad_2613
            AVI: Avi_1913(icdA)
            REC: RHECIAT_CH0002414(icd)
            RLE: RL2631(icd)
            RLT: Rleg2_1953
            RLG: Rleg_2164
            LAS: CLIBASIA_04005
            LSO: CKC_04365
            BME: BMEI0791
            BMI: BMEA_A1243
            BMF: BAB1_1221
            BMB: BruAb1_1204
            BMC: BAbS19_I11370
            BMS: BR1199
            BMT: BSUIS_A1247
            BOV: BOV_1161
            BCS: BCAN_A1221
            BMR: BMI_I1210
            OAN: Oant_1992
            BJA: blr5747(icdA)
            BRA: BRADO2759(icd)
            BBT: BBta_5427(icd)
            RPA: RPA3834(idh)
            RPB: RPB_3732
            RPC: RPC_1576
            RPD: RPD_1737
            RPE: RPE_1602
            RPT: Rpal_4362
            RPX: Rpdx1_1511
            NWI: Nwi_1294
            NHA: Nham_1623
            OCA: OCAR_5440
            BHE: BH10050(icdA)
            BQU: BQ07780(icdA)
            BBK: BARBAKC583_0743
            BTR: Btr_1381(icdA)
            BGR: Bgr_12280(icdA)
            BCD: BARCL_0663(icdA)
            XAU: Xaut_4569
            AZC: AZC_1865
            SNO: Snov_2160
            MEX: Mext_3141
            MEA: Mex_1p3354(icd)
            MDI: METDI3925(icd)
            MRD: Mrad2831_5765
            MET: M446_2631
            MPO: Mpop_3338
            MCH: Mchl_3463
            MNO: Mnod_4814
            BID: Bind_1133 Bind_2545
            MSL: Msil_3530
            HDN: Hden_2121
            RVA: Rvan_1989
            CCR: CC_2522
            CCS: CCNA_02607
            CAK: Caul_3527
            CSE: Cseg_1184
            PZU: PHZ_c0989(icd)
            BSB: Bresu_1170
            AEX: Astex_2510
            SIL: SPOA0315(icd)
            SIT: TM1040_0477
            RSP: RSP_0446 RSP_1559(icd)
            RSH: Rsph17029_0210 Rsph17029_2099
            RSQ: Rsph17025_2367 Rsph17025_3039
            RSK: RSKD131_1778 RSKD131_2956
            RCP: RCAP_rcc01887(icd)
            JAN: Jann_2371 Jann_2372
            RDE: RD1_2204(icd) RD1_2704(icd)
            PDE: Pden_2961
            DSH: Dshi_1986(icd)
            KVU: EIO_1866(icd)
            MMR: Mmar10_1011
            HNE: HNE_1177
            HBA: Hbal_0575
            ZMO: ZMO0544
            ZMN: Za10_0709
            NAR: Saro_1282
            SAL: Sala_1964
            SWI: Swit_0457
            SJP: SJA_C1-24210(icd)
            ELI: ELI_07700
            GOX: GOX1336
            GBE: GbCGDNIH1_1366
            ACR: Acry_0565 Acry_2029
            GDI: GDI_0904(icd)
            GDJ: Gdia_1117
            APT: APA01_06250
            RRU: Rru_A0356
            RCE: RC1_0906(icd)
            MAG: amb0607 amb0608
            AZL: AZL_016830(icd) AZL_016900(idh)
            PBR: PB2503_11134
            APB: SAR116_0090
            MGM: Mmc1_1603
            DIN: Selin_2134
            BSU: BSU29130(icd)
            BSS: BSUW23_14160(icd)
            BAN: BA_4838(citC)
            BAR: GBAA_4838(citC)
            BAT: BAS4487
            BAH: BAMEG_4869(icd)
            BAI: BAA_4849(icd)
            BAL: BACI_c45850(citC)
            BCR: BCAH187_A4719(citC)
            BCB: BCB4264_A4703(citC)
            BCU: BCAH820_4708(citC)
            BCG: BCG9842_B0535(citC)
            BCQ: BCQ_4397(citC)
            BCX: BCA_4703(icd)
            BCY: Bcer98_3277
            BTB: BMB171_C4236(citC)
            BWE: BcerKBAB4_4423
            BLI: BL00398(icd)
            BLD: BLi03061(icd)
            BAY: RBAM_026170(icd)
            BAO: BAMF_2716(icd)
            BAE: BATR1942_12350
            BPU: BPUM_2555(icd)
            BPF: BpOF4_03360(idhA)
            BMQ: BMQ_4769(icd)
            BMD: BMD_4755(icd)
            BSE: Bsel_1354
            BCO: Bcell_2843 Bcell_3219
            GWC: GWCH70_0444 GWCH70_2678
            GYM: GYMC10_4927
            GYC: GYMC61_0782
            GYA: GYMC52_2770
            GCT: GC56T3_0758
            GMC: GY4MC1_0834
            AFL: Aflv_0505(icd)
            SAU: SA1517(citC)
            SAV: SAV1694(citC)
            SAW: SAHV_1680(citC)
            SAM: MW1638(citC)
            SAX: USA300HOU_1681(icd)
            SAD: SAAV_1684(icd)
            SEP: SE1370
            SHA: SH1231(citC)
            SSP: SSP1072
            SCA: Sca_1300(icd)
            SLG: SLGD_01235
            SSD: SPSINT_1452
            LMO: lmo1566(citC)
            LMF: LMOf2365_1588(icd)
            LMH: LMHCC_1003(icd)
            LMC: Lm4b_01577(citC)
            LMN: LM5578_1712(citC)
            LMY: LM5923_1664(citC)
            LIN: lin1601
            LSG: lse_1481(citC)
            LSP: Bsph_4121
            ESI: Exig_2208
            EAT: EAT1b_0666
            MCL: MCCL_1361(citC)
            BBE: BBR47_13900(icd)
            PJD: Pjdr2_4472
            PPY: PPE_01587(icd)
            PPM: PPSC2_c1756
            AAC: Aaci_1557 Aaci_2348
            BTS: Btus_2429
            LLA: L71075(icd)
            LLK: LLKF_0648(icd)
            LLC: LACR_0699
            LLM: llmg_0637(icd)
            SMU: SMU.672(idh)
            SMC: SmuNN2025_1319(idh)
            STC: str1266(icd)
            STL: stu1266(icd)
            STE: STER_1244
            SSA: SSA_0704
            SSU: SSU05_1202
            SSV: SSU98_1216
            SSB: SSUBM407_0746(icd)
            SSI: SSU1040(icd)
            SSS: SSUSC84_1078(icd)
            SGO: SGO_1611(icd)
            SGA: GALLO_0709(icd)
            LFE: LAF_0939
            CTH: Cthe_0285
            CBK: CLL_A2649
            CBT: CLH_2401
            CBE: Cbei_4199
            CKL: CKL_0546(idh)
            CKR: CKR_0483
            CCE: Ccel_2576
            CSH: Closa_3348
            STH: STH2544
            SLP: Slip_0511
            AFN: Acfer_0606
            DSY: DSY3882
            DHD: Dhaf_1523
            DRM: Dred_3254
            DAE: Dtox_2878
            TJR: TherJR_0875
            HMO: HM1_1471(icd)
            EEL: EUBELI_01275
            ERE: EUBREC_1968
            BPB: bpr_I1102(icd)
            RAL: Rumal_3116
            TTE: TTE0387(icd)
            TEX: Teth514_0327
            TPD: Teth39_1882
            TIT: Thit_0372
            TMT: Tmath_0443
            TBO: Thebr_1931
            TTM: Tthe_2244
            MTU: Rv0066c(icd2) Rv3339c(icd1)
            MTC: MT0072(icd-1) MT3442(icd-2)
            MRA: MRA_0068(icd2) MRA_3380(icd1)
            MTF: TBFG_10066 TBFG_13371
            MTB: TBMG_00066(TBMG_00066.1) TBMG_03388(TBMG_03388.1)
            MBO: Mb0067c(icd2) Mb3371c(icd1)
            MBB: BCG_0097c(icd2) BCG_3409c(icd1)
            MBT: JTY_0068(icd2) JTY_3409(icd1)
            MLE: ML2672(icd2)
            MLB: MLBr_02672(icd2)
            MPA: MAP3455c(icd1) MAP3456c(icd2)
            MAV: MAV_4311 MAV_4313 MAV_5105
            MSM: MSMEG_1654
            MUL: MUL_4939(icd2)
            MVA: Mvan_3212
            MGI: Mflv_3455
            MAB: MAB_3686c
            MMC: Mmcs_1209
            MKM: Mkms_1226
            MJL: Mjls_1236
            MSP: Mspyr1_27920
            MMI: MMAR_0158(icd2) MMAR_1186(icd1)
            CGL: NCgl0634(cgl0664)
            CGB: cg0766(icd)
            CGT: cgR_0784
            CEF: CE0682(icd)
            CDI: DIP0631(icd)
            CJK: jk1693(icd)
            CUR: cur_0425
            CAR: cauri_0526(icd)
            CKP: ckrop_1566(icd)
            CPU: cpfrc_00461(icd)
            NFA: nfa9230
            RHA: RHA1_ro00618 RHA1_ro06238
            RER: RER_20050(icd)
            ROP: ROP_47620(icd) ROP_62970(icd)
            REQ: REQ_34420
            GBR: Gbro_2518
            TPR: Tpau_2261
            SRT: Srot_1311 Srot_1886
            SCO: SCO7000(idh)
            SMA: SAV_7214(icdA)
            SGR: SGR_1224
            SCB: SCAB_12211(idh)
            LXX: Lxx19490(icd)
            CMI: CMM_2537(icdA)
            CMS: CMS_0599
            ART: Arth_1092
            AAU: AAur_1201
            ACH: Achl_1170
            AAI: AARI_06450(icd)
            RSA: RSal33209_0245
            KRH: KRH_08030(icd)
            MLU: Mlut_04530
            BCV: Bcav_3007
            BFA: Bfae_22050
            JDE: Jden_0685
            KSE: Ksed_19690
            XCE: Xcel_3100
            SKE: Sked_37720
            CFL: Cfla_2528
            ICA: Intca_0556
            PAC: PPA1738
            PAK: HMPREF0675_4792
            PFR: PFREUD_06870(icd)
            NCA: Noca_3575
            KFL: Kfla_1537
            TFU: Tfu_2568
            NDA: Ndas_3960
            TCU: Tcur_4210
            SRO: Sros_1254
            FRA: Francci3_2203
            FRE: Franean1_4274
            FRI: FraEuI1c_6152
            FAL: FRAAL3297(icd)
            ACE: Acel_0388
            NML: Namu_1281
            GOB: Gobs_4413
            KRA: Krad_3988
            SEN: SACE_6636(icd-2)
            SVI: Svir_05050
            TBI: Tbis_0665
            AMD: AMED_0833(icd)
            AMI: Amir_6478
            STP: Strop_3793
            SAQ: Sare_4173
            MAU: Micau_5381
            MIL: ML5_0474
            CAI: Caci_7976
            SNA: Snas_1222
            AHE: Arch_1451
            MCU: HMPREF0573_10107
            BLO: BL1499(icd1)
            BLJ: BLD_0398(icd)
            BLN: Blon_1051
            BLL: BLJ_1107
            BLB: BBMN68_366(icd)
            BAD: BAD_0776(icd1)
            BLA: BLA_1290
            BLC: Balac_0768
            BLT: Balat_0768
            BDE: BDP_1207(icdA)
            BBI: BBIF_1018(icdA)
            BBP: BBPR_1073(icdA)
            CWO: Cwoe_0911
            AFO: Afer_1881 Afer_1984
            SHI: Shel_06080
            ELE: Elen_1459
            OLS: Olsu_0358
            PCU: pc1783(icd)
            WCH: wcw_1730(icd)
            SSM: Spirs_2856
            LIL: LA_4171(leuB)
            LIC: LIC13328
            LBJ: LBJ_2800(leuB-2)
            LBL: LBL_0271(leuB-2)
            LBI: LEPBI_I2891(icd)
            LBF: LBF_2792(icdA)
            BRM: Bmur_2697
            BPO: BP951000_0369(idh)
            ABA: Acid345_1950
            ACA: ACP_0089(icd1) ACP_0990(icd2)
            TSA: AciPR4_1000
            SUS: Acid_2824
            BTH: BT_2071
            BFR: BF3754
            BFS: BF3542(icd)
            BVU: BVU_1960
            BHL: Bache_3314
            PDI: BDI_1075
            PPN: Palpr_1044
            SRU: SRU_1973(icd)
            SRM: SRM_02189(icd)
            RMR: Rmar_1401 Rmar_2190
            CHU: CHU_1228(icd)
            DFE: Dfer_3730
            SLI: Slin_3335 Slin_4767
            LBY: Lbys_3113
            MTT: Ftrac_1656 Ftrac_3556
            CPI: Cpin_6591 Cpin_6592
            PHE: Phep_0734
            GFO: GFO_0618(icd)
            FJO: Fjoh_2181
            FPS: FP1872(icd)
            COC: Coch_0970
            RBI: RB2501_12442
            ZPR: ZPR_3604
            CAT: CA2559_06770
            RAN: Riean_0199
            FBC: FB2170_13543
            CAO: Celal_0013 Celal_3005
            FBA: FIC_00973
            BBL: BLBBGE_272(icd)
            FSU: Fisuc_0675
            OTE: Oter_3132
            CAA: Caka_2526
            MIN: Minf_0939(leuB)
            AMU: Amuc_1880
            GAU: GAU_2329(idh)
            RBA: RB1593(icd)
            IPA: Isop_2834
            TAI: Taci_0021
            SYN: slr1289(icd)
            SYC: syc2372_d(icd)
            SYF: Synpcc7942_1719
            SYD: Syncc9605_0161
            SYE: Syncc9902_0191
            SYR: SynRCC307_0153(icd)
            SYX: SynWH7803_0217(icd)
            SYP: SYNPCC7002_A0838(icd)
            MAR: MAE_62530(icd)
            CYT: cce_3202(icd)
            CYP: PCC8801_3969
            CYC: PCC7424_0313
            CYN: Cyan7425_2071
            CYH: Cyan8802_4014
            CYJ: Cyan7822_1400
            GVI: gll3998
            ANA: alr1827(icd)
            NPU: Npun_R5474
            AVA: Ava_4831
            NAZ: Aazo_1215
            PMN: PMN2A_1170
            PMI: PMT9312_1688
            PMH: P9215_18691(icd)
            PMJ: P9211_17171
            TER: Tery_0071
            AMR: AM1_5754(icd)
            CTE: CT0351(icd)
            CPC: Cpar_1686
            CCH: Cag_1410
            CPH: Cpha266_0680
            CPB: Cphamn1_0799
            CLI: Clim_0553
            PVI: Cvib_0507
            PLT: Plut_0459
            PPH: Ppha_2213
            PAA: Paes_1677
            CTS: Ctha_0632
            RRS: RoseRS_0785
            RCA: Rcas_1241
            CAU: Caur_2895
            CAG: Cagg_1050
            CHL: Chy400_3133
            TRO: trd_0647
            ATM: ANT_03940
            DRA: DR_1540
            DGE: Dgeo_1166
            DDR: Deide_13580
            DMR: Deima_1499
            TRA: Trad_1633
            TTH: TTC1172
            TTJ: TTHA1535
            TSC: TSC_c18520(icd1)
            MRB: Mrub_1134 Mrub_1505
            MSV: Mesil_1295 Mesil_1684
            OPR: Ocepr_1260
            AAE: aq_1512(icd)
            HYA: HY04AAS1_1432
            HTH: HTH_0836(icd)
            TAL: Thal_0646
            SUL: SYO3AOP1_0694
            SAF: SULAZ_0526
            PMX: PERMA_1716
            TAM: Theam_1023
            TMA: TM1148
            TRQ: TRQ2_1668
            TNA: CTN_1427
            TNP: Tnap_1622
            KOL: Kole_1227
            DTH: DICTH_1941
            DTU: Dtur_0212
            NDE: NIDE0837(idh)
            DDF: DEFDS_0918(icd)
            DAP: Dacet_2347
            CNI: Calni_0462
            MAC: MA4265
            MBA: Mbar_A0623
            MMA: MM_0642 MM_1003
            MBU: Mbur_1073
            MMH: Mmah_0582
            MEV: Metev_0798
            MPD: MCP_0437
            AFU: AF0647(icd)
            APO: Arcpr_0248
            FPL: Ferp_0862
            HAL: VNG1873G(icd)
            HSL: OE3634F(icd)
            HMA: rrnAC3419(icd)
            HWA: HQ3212A(icd)
            NPH: NP2430A(icd)
            HLA: Hlac_2330
            HUT: Huta_0281
            HMU: Hmuk_1506
            HTU: Htur_0547
            NMG: Nmag_2939
            HVO: HVO_2588(icd)
            HJE: HacjB3_06550
            HBO: Hbor_09930
            TAC: Ta0117
            TVO: TVN0195
            PTO: PTO0168 PTO0426
            PFU: PF0202
            RCI: RCIX1801(icd)
            APE: APE_0689.1
            IHO: Igni_1064
            IAG: Igag_1763
            SSO: SSO2182(idh)
            STO: ST2166
            SAI: Saci_2375(icd)
            SIS: LS215_2965
            SIA: M1425_2800
            SIM: M1627_2852
            SID: M164_2781
            SIY: YG5714_2980
            SIN: YN1551_3171
            SII: LD85_3130
            MSE: Msed_0703
            PAI: PAE1651
            PIS: Pisl_1672
            PCL: Pcal_0579
            PAS: Pars_1842
            CMA: Cmaq_1738
            TNE: Tneu_0698
            VDI: Vdis_2027
            ASC: ASAC_0817
            NMR: Nmar_1379
            CSY: CENSYa_0471
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.42
            IUBMB Enzyme Nomenclature: 1.1.1.42
            ExPASy - ENZYME nomenclature database: 1.1.1.42
            BRENDA, the Enzyme Database: 1.1.1.42
            CAS: 9028-48-2
///
ENTRY       EC 1.1.1.43                 Enzyme
NAME        phosphogluconate 2-dehydrogenase;
            6-phosphogluconic dehydrogenase;
            phosphogluconate dehydrogenase;
            gluconate 6-phosphate dehydrogenase;
            6-phosphogluconate dehydrogenase (NAD+);
            2-keto-6-phosphogluconate reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase
REACTION    6-phospho-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate +
            NAD(P)H + H+ [RN:R02032 R02034]
ALL_REAC    R02032 R02034
SUBSTRATE   6-phospho-D-gluconate [CPD:C00345];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     6-phospho-2-dehydro-D-gluconate [CPD:C01218];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13894458]
  AUTHORS   FRAMPTON EW, WOOD WA.
  TITLE     Carbohydrate oxidation by Pseudomonas fluorescens VI. Conversion of
            2-keto-6-phosphogluconate to pyruvate.
  JOURNAL   J. Biol. Chem. 236 (1961) 2571-7.
  ORGANISM  Pseudomonas fluorescens
PATHWAY     ec00030  Pentose phosphate pathway
            ec00480  Glutathione metabolism
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00032  phosphogluconate 2-dehydrogenase
GENES       PAE: PA2263
            PAU: PA14_35320(kguD)
            PAP: PSPA7_2977
            PPU: PP_3376(kguD)
            PPF: Pput_2382
            PPG: PputGB1_2568
            PPW: PputW619_2571
            PFL: PFL_2717
            REH: H16_B1813(kguD)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.43
            IUBMB Enzyme Nomenclature: 1.1.1.43
            ExPASy - ENZYME nomenclature database: 1.1.1.43
            BRENDA, the Enzyme Database: 1.1.1.43
            CAS: 9001-82-5
///
ENTRY       EC 1.1.1.44                 Enzyme
NAME        phosphogluconate dehydrogenase (decarboxylating);
            phosphogluconic acid dehydrogenase;
            6-phosphogluconic dehydrogenase;
            6-phosphogluconic carboxylase;
            6-phosphogluconate dehydrogenase (decarboxylating);
            6-phospho-D-gluconate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)
REACTION    6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH
            [RN:R01528]
ALL_REAC    R01528
SUBSTRATE   6-phospho-D-gluconate [CPD:C00345];
            NADP+ [CPD:C00006]
PRODUCT     D-ribulose 5-phosphate [CPD:C00199];
            CO2 [CPD:C00011];
            NADPH [CPD:C00005]
COFACTOR    Manganese [CPD:C00034]
COMMENT     Certain preparations reduce NAD+ as well as NADP+.
REFERENCE   1  [PMID:14904376]
  AUTHORS   DICKENS F, GLOCK GE.
  TITLE     Direct oxidation of glucose-6-phosphate, 6-phosphogluconate and
            pentose-5-phosphates by enzymes of animal origin.
  JOURNAL   Biochem. J. 50 (1951) 81-95.
  ORGANISM  Rattus norvegicus [GN:rno], Oryctolagus cuniculus
REFERENCE   2  [PMID:14487824]
  AUTHORS   PONTREMOLI S, DE FLORA A, GRAZI E, MANGIAROTTIG, BONSIGNORE A,
            HORECKER BL.
  TITLE     Crystalline D-gluconate 6-phosphate dehydrogenase.
  JOURNAL   J. Biol. Chem. 236 (1961) 2975-80.
  ORGANISM  Candida utilis
REFERENCE   3  [PMID:13093611]
  AUTHORS   SCOTT DB, COHEN SS
  TITLE     The oxidative pathway of carbohydrate metabolism in Escherichia
            coli. 1. The isolation and properties of glucose 6-phosphate
            dehydrogenase and 6-phosphogluconate dehydrogenase.
  JOURNAL   Biochem. J. 55 (1953) 23-33.
REFERENCE   4  [PMID:13426085]
  AUTHORS   SCOTT DB, COHEN SS
  TITLE     The oxidative pathway of carbohydrate metabolism in Escherichia
            coli. V. Isolation and identification of ribulose phosphate produced
            from 6-phosphogluconate by the dehydrogenase of E. coli.
  JOURNAL   Biochem. J. 65 (1957) 686-9.
PATHWAY     ec00030  Pentose phosphate pathway
            ec00480  Glutathione metabolism
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00033  6-phosphogluconate dehydrogenase
GENES       HSA: 5226(PGD)
            PON: 100433341
            MMU: 110208(Pgd)
            RNO: 100360180
            CFA: 478236(PGD)
            AML: 100479518(PGD)
            BTA: 514939(PGD)
            SSC: 397546(PGD)
            ECB: 100146298
            OAA: 100078793
            GGA: 419450(PGD)
            XLA: 398848(pgd) 735164
            XTR: 100491794
            DRE: 406762(pgd)
            BFO: BRAFLDRAFT_118445
            CIN: 100178165
            SPU: 583873
            DME: Dmel_CG15093 Dmel_CG3724(Pgd)
            DPO: Dpse_GA17642
            DAN: Dana_GF21463
            DER: Dere_GG12910
            DPE: Dper_GL14162
            DSE: Dsec_GM19200
            DSI: Dsim_GD16588(Dsim_Pgd)
            DWI: Dwil_GK10231
            DYA: Dyak_GE16239(Dyak_Pgd)
            DGR: Dgri_GH24572
            DMO: Dmoj_GI11069
            DVI: Dvir_GJ16930
            AGA: AgaP_AGAP004197
            AAG: AaeL_AAEL005931
            CQU: CpipJ_CPIJ001316
            AME: 552712(Pgd)
            NVI: 100120510(NV16426)
            TCA: 660752
            API: 100167791
            ISC: IscW_ISCW010101
            CEL: T25B9.9
            CBR: CBG17632
            BMY: Bm1_52945
            SMM: Smp_071840
            NVE: NEMVE_v1g230495
            HMG: 100211738
            TAD: TRIADDRAFT_64046
            ATH: AT1G64190 AT3G02360 AT5G41670
            POP: POPTR_640402 POPTR_831203 POPTR_831204 POPTR_837012
            RCU: RCOM_0876630 RCOM_0901440
            VVI: 100241717 100246134
            OSA: 4339892 4350528
            SBI: SORBI_05g016740
            ZMA: 100274495 541700(pgd2)
            PPP: PHYPADRAFT_109688 PHYPADRAFT_183544 PHYPADRAFT_189273
                 PHYPADRAFT_227811
            CRE: CHLREDRAFT_192597(GND1a)
            VCN: VOLCADRAFT_109207
            OLU: OSTLU_32825
            OTA: Ot07g04130
            CME: CML036C CML059C CMM231C CMS195C CMX012C
            SCE: YGR256W(GND2) YHR183W(GND1)
            AGO: AGOS_AFR129W
            KLA: KLLA0A09339g
            LTH: KLTH0B08668g
            PPA: PAS_chr3_0277
            VPO: Kpol_1067p2
            ZRO: ZYRO0D07876g
            CGR: CAGL0M13343g
            DHA: DEHA2D06160g
            PIC: PICST_69500(GND1)
            PGU: PGUG_05084
            LEL: LELG_03480
            CAL: CaO19.12491(DOR14)
            CTP: CTRG_03660
            CDU: CD36_12850
            YLI: YALI0B15598g
            CLU: CLUG_04244
            NCR: NCU00837 NCU03100
            PAN: PODANSg4621 PODANSg5877
            MGR: MGG_00175(MG00175.4)
            FGR: FG01111.1
            SSL: SS1G_09870
            BFU: BC1G_02744
            ANI: AN3954.2
            AFM: AFUA_6G08050 AFUA_6G08730
            NFI: NFIA_053740 NFIA_054380
            AOR: AO090001000547 AO090003000121
            ANG: An11g02040 An11g06120
            AFV: AFLA_036840 AFLA_128510
            ACT: ACLA_082590 ACLA_083680
            PCS: Pc12g08920 Pc12g10940 Pc19g00410
            CIM: CIMG_01153
            CPW: CPC735_052290
            URE: UREG_01088 UREG_04836
            PNO: SNOG_00430 SNOG_15879
            TML: GSTUM_00005638001
            SPO: SPBC660.16
            CNE: CNK01050
            CNB: CNBK2450
            LBC: LACBIDRAFT_293971
            MPR: MPER_10462
            CCI: CC1G_03705
            SCM: SCHCODRAFT_13226 SCHCODRAFT_50168
            UMA: UM02577.1
            MGL: MGL_3885
            ECU: ECU05_0860
            MBR: MONBRDRAFT_20098
            NGR: NAEGRDRAFT_77240
            DDI: DDB_G0277885(gnd)
            PFA: PF14_0520
            PFD: PFDG_04224
            PFH: PFHG_00665
            PYO: PY00858
            PCB: PC000964.01.0
            PBE: PB000629.00.0
            PKN: PKH_125180
            PVX: PVX_117745
            TAN: TA19350
            TPV: TP01_0193
            BBO: BBOV_IV004060(23.m05761)
            TGO: TGME49_042600 TGME49_107850
            TBR: Tb09.211.3180
            TCR: 507011.269 510663.70
            LMA: LmjF35.3340
            LIF: LinJ35.3440
            LBZ: LbrM34_V2.3250
            TVA: TVAG_006140 TVAG_553420
            PTI: PHATRDRAFT_45333(6PGDH)
            TPS: THAPSDRAFT_33343(PGD1) THAPSDRAFT_3900
            PIF: PITG_10032
            ECO: b2029(gnd)
            ECJ: JW2011(gnd)
            ECD: ECDH10B_2177(gnd)
            EBW: BWG_1820(gnd)
            ECE: Z3191(gnd)
            ECS: ECs2830
            ECF: ECH74115_2962(gnd)
            ETW: ECSP_2780(gnd)
            EOJ: ECO26_2940(gnd)
            EOI: ECO111_2755(gnd)
            EOH: ECO103_2508(gnd)
            ECG: E2348C_2170(gnd)
            EOK: G2583_2553(gnd)
            ECC: c2556(gnd)
            ECP: ECP_2072
            ECI: UTI89_C2302(gnd)
            ECV: APECO1_1126(gnd)
            ECX: EcHS_A2183(gnd)
            ECW: EcE24377A_2320(gnd)
            ECM: EcSMS35_1031(gnd)
            ECY: ECSE_2303
            ECR: ECIAI1_2109(gnd)
            ECQ: ECED1_2378(gnd)
            ECK: EC55989_2288(gnd)
            ECT: ECIAI39_0989(gnd)
            EUM: ECUMN_2371(gnd)
            ECZ: ECS88_2128(gnd)
            ECL: EcolC_1613
            EBR: ECB_01931(gnd)
            EBD: ECBD_1630
            EFE: EFER_2112(gnd)
            STY: STY2290(gnd)
            STT: t0792(gnd)
            STM: STM2081(gnd)
            SPT: SPA0790(gnd)
            SEK: SSPA0740
            SPQ: SPAB_00951
            SEI: SPC_1631(gnd)
            SEC: SC2091(gnd)
            SEH: SeHA_C2307(gnd)
            SEE: SNSL254_A2260(gnd)
            SEW: SeSA_A2309(gnd)
            SEA: SeAg_B2206(gnd)
            SED: SeD_A2420(gnd)
            SEG: SG2111(gnd)
            SET: SEN2080(gnd)
            SES: SARI_00803
            YPE: YPO1541(gnd)
            YPK: y2629(gnd)
            YPA: YPA_0836
            YPN: YPN_2439
            YPM: YP_1430(gnd)
            YPP: YPDSF_1435
            YPG: YpAngola_A3177(gnd)
            YPZ: YPZ3_1406(gnd)
            YPS: YPTB1553(gnd)
            YPI: YpsIP31758_2436(gnd)
            YPY: YPK_2535
            YPB: YPTS_1663
            YEN: YE2773(gnd)
            SFL: SF2091(gnd)
            SFX: S2212(gnd)
            SFV: SFV_2089(gnd)
            SSN: SSON_2100(gnd)
            SBO: SBO_0858(gnd)
            SBC: SbBS512_E1202(gnd)
            SDY: SDY_2212(gnd)
            ECA: ECA1444(gnd)
            PCT: PC1_1320
            PWA: Pecwa_3014
            ETA: ETA_13450(gnd)
            EPY: EpC_14090(gnd)
            EAM: EAMY_2229(gnd)
            EAY: EAM_2150(gnd)
            EBI: EbC_29190(gnd)
            PLU: plu1560(gnd)
            PAY: PAU_02885(gnd)
            BUC: BU107(gnd)
            BAS: BUsg100(gnd)
            BAB: bbp101(gnd)
            BCC: BCc_071(gnsD)
            BAP: BUAP5A_105(gnd)
            BAU: BUAPTUC7_106(gnd)
            SGL: SG1122
            ENT: Ent638_2642
            ENC: ECL_03352(gnd)
            ESC: Entcl_1664
            ESA: ESA_01189
            CTU: Ctu_27250(gnd)
            KPN: KPN_02499(gnd)
            KPE: KPK_1667(gnd)
            KPU: KP1_3704(gnd)
            KVA: Kvar_1562
            CKO: CKO_00756
            CRO: ROD_21671(gnd)
            SPE: Spro_1608
            PMR: PMI0655(gnd)
            EIC: NT01EI_1320
            ETR: ETAE_1212(gnd)
            BFL: Bfl470(gnd)
            BPN: BPEN_485(gnd)
            BVA: BVAF_471(gnd)
            HDE: HDEF_0040(gnd)
            DDA: Dd703_1204
            DDC: Dd586_1255
            DDD: Dda3937_04507(gnd)
            DZE: Dd1591_2847
            XBO: XBJ1_0927(gnd)
            XNE: XNC1_1504(gnd)
            PAM: PANA_2481(gnd) PANA_4019(yqeC)
            PVA: Pvag_1962(gnd)
            PAO: Pat9b_2575
            HIN: HI0553(gnd)
            HIT: NTHI0681(gnd)
            HIP: CGSHiEE_00210
            HIQ: CGSHiGG_06045
            HIF: HIBPF17740
            HIL: HICON_08640
            HDU: HD0833(gnd)
            HAP: HAPS_0833(gnd)
            HSO: HS_1654(gnd)
            HSM: HSM_1816
            PMU: PM1554(gnd)
            MSU: MS0013(gnd)
            APL: APL_1305(gnd)
            APJ: APJL_1319(gnd)
            APA: APP7_1357
            ASU: Asuc_0232
            AAP: NT05HA_2095
            AAT: D11S_0524
            XCC: XCC3439(gndA)
            XCB: XC_0725
            XCA: xccb100_0757(gnd)
            XCV: XCV0741(gndA)
            XAC: XAC0680(gndA)
            XOO: XOO3939(gndA)
            XOM: XOO_3717
            XOP: PXO_04301(gnd)
            XAL: XALc_0826(gnd)
            SML: Smlt4042
            SMT: Smal_3438
            PSU: Psesu_2564
            VCH: VCA0898
            VCO: VC0395_0339(gnd)
            VCM: VCM66_A0858(gnd)
            VCJ: VCD_000433
            VVU: VV1_2682
            VVY: VV1607
            VVM: VVM_03166
            VPA: VP1708
            VHA: VIBHAR_02427
            VSP: VS_1306 VS_II0409
            VEX: VEA_003325
            VFI: VF_A0470(gnd)
            VFM: VFMJ11_A0520(gnd)
            VSA: VSAL_II0685(gnd)
            PPR: PBPRA1444
            PPU: PP_4043(gnd)
            PPF: Pput_1795
            PPG: PputGB1_3647
            PPW: PputW619_1830
            PST: PSPTO_3122(gnd)
            PSB: Psyr_2989
            PSP: PSPPH_2251
            PFL: PFL_3144
            PFO: Pfl01_2586
            PFS: PFLU2691
            PEN: PSEEN1939(gnd)
            CJA: CJA_3099(gnd)
            SON: SO_1902(gnd)
            SDN: Sden_1935
            SFR: Sfri_2724
            SAZ: Sama_1365
            SBL: Sbal_2824
            SBM: Shew185_2842
            SBN: Sbal195_2969
            SBP: Sbal223_1534
            SLO: Shew_2561
            SPC: Sputcn32_1723
            SSE: Ssed_1461
            SPL: Spea_2794
            SHE: Shewmr4_1609
            SHM: Shewmr7_1684
            SHN: Shewana3_1677
            SHW: Sputw3181_2302
            SHL: Shal_2899
            SWD: Swoo_3220
            SWP: swp_3432
            SVO: SVI_3128(gnd)
            CPS: CPS_2341(gnd)
            PHA: PSHAa1407
            PAT: Patl_2110
            PSM: PSM_A1445
            SDE: Sde_0635
            AMC: MADE_01255
            PIN: Ping_2752 Ping_2937
            TTU: TERTU_0484(gnd)
            FBL: Fbal_3127
            MCA: MCA1950(gnd)
            TCX: Tcr_1215
            NOC: Noc_2061
            NHL: Nhal_2849
            NWA: Nwat_1039
            ALV: Alvin_1628
            TGR: Tgr7_0873
            HNA: Hneap_0997
            CSA: Csal_0666
            MMW: Mmwyl1_3505
            DNO: DNO_1236(gnd)
            AFE: Lferr_1689
            AFR: AFE_2024
            BCI: BCI_0397(gnd)
            CRP: CRP_039
            NMA: NMA0262(gnd)
            NME: NMB0015(gnd)
            NMC: NMC2153(gnd)
            NMN: NMCC_0017(gnd)
            NMI: NMO_0001(gnd)
            NGO: NGO1914
            NGK: NGK_2339
            NLA: NLA_20670(gnd)
            LHK: LHK_01920
            BMA: BMAA0420(gnd)
            BML: BMA10229_1798(gnd)
            BMN: BMA10247_A0469(gnd)
            BPS: BPSS1749(gnd)
            BPM: BURPS1710b_A0828(gnd)
            BPL: BURPS1106A_A2376(gnd)
            BPD: BURPS668_A2515(gnd)
            BTE: BTH_II0631(gnd)
            BVI: Bcep1808_4384
            BUR: Bcep18194_B2181
            BCN: Bcen_4459
            BCH: Bcen2424_3907
            BCM: Bcenmc03_3620
            BCJ: BCAM0941(gnd)
            BAM: Bamb_3285
            BAC: BamMC406_3801
            BMU: Bmul_4676
            BMJ: BMULJ_03838(gnd)
            BXE: Bxe_B1341 Bxe_B2210
            BPH: Bphy_4715
            BPY: Bphyt_5277 Bphyt_5973
            BGL: bglu_2g07680
            BGE: BC1002_3424 BC1002_3885
            BRH: RBRH_01800
            RFR: Rfer_4033
            PNA: Pnap_4501
            VAP: Vapar_1694
            VPE: Varpa_1860
            NEU: NE0397
            NET: Neut_2144 Neut_2432
            NMU: Nmul_A1623
            DAR: Daro_2069
            TBD: Tbd_2123
            MFA: Mfla_0918 Mfla_1062 Mfla_2599
            MMB: Mmol_0143
            MEH: M301_2666
            MEI: Msip34_1094
            MEP: MPQ_1149(gnd)
            APP: CAP2UW1_2361
            SLT: Slit_0394
            GCA: Galf_1905
            GME: Gmet_2620
            PCA: Pcar_0925(gnd)
            PPD: Ppro_2249
            DDE: Dde_3470
            DMA: DMR_05560(gnd)
            DBA: Dbac_0340
            DRT: Dret_2486
            DAK: DaAHT2_1236
            DPR: Despr_2153
            DAL: Dalk_3008
            ADE: Adeh_1438
            ACP: A2cp1_2509
            AFW: Anae109_0596
            ANK: AnaeK_2422
            MXA: MXAN_0951(gnd)
            SCL: sce3546(gnd1) sce6035(gnd2)
            DBR: Deba_3180
            MLO: mll3321 mlr4206
            MCI: Mesci_1061 Mesci_1692
            MES: Meso_3946
            SME: SMc04262(gnd)
            SMD: Smed_1732
            RHI: NGR_c17890
            ATU: Atu1526(gntZ) Atu4834
            ARA: Arad_2442(gnd) Arad_2660(gnd)
            AVI: Avi_2396(gnd) Avi_7571
            RET: RHE_CH02468(gnd) RHE_CH03488(ypch01234)
            REC: RHECIAT_CH0002570(gnd) RHECIAT_CH0003729
            RLE: RL2807(gnd) RL3998(gntZ)
            RLT: Rleg2_2107 Rleg2_3229
            RLG: Rleg_2349 Rleg_3524
            LAS: CLIBASIA_03015(gnd)
            LSO: CKC_00655
            BME: BMEII1124
            BMI: BMEA_B0114(gnd)
            BMF: BAB2_0109(gnd)
            BMB: BruAb2_0109(gnd)
            BMC: BAbS19_II01000
            BMS: BRA0111(gnd)
            BMT: BSUIS_B0116(gnd)
            BOV: BOV_A0101(gnd)
            BCS: BCAN_B0115(gnd)
            BMR: BMI_II111(gnd)
            OAN: Oant_4233
            BJA: blr6759
            BRA: BRADO5810
            BBT: BBta_6316 BBta_p0095
            RPA: RPA3635(gnd)
            RPB: RPB_1891
            RPC: RPC_3671
            RPD: RPD_3475
            RPE: RPE_3709
            RPT: Rpal_4156
            RPX: Rpdx1_1716
            NWI: Nwi_2642
            NHA: Nham_3270
            OCA: OCAR_5069(gnd)
            SNO: Snov_3857
            MEX: Mext_4826
            MEA: Mex_1p5283(gnd)
            MDI: METDI5883(gnd)
            MRD: Mrad2831_2307
            MET: M446_6707
            MPO: Mpop_5371
            MCH: Mchl_5293
            MNO: Mnod_7446
            BID: Bind_0459
            RVA: Rvan_2950
            PZU: PHZ_p0183
            JAN: Jann_3252
            PDE: Pden_2393
            KVU: EIO_0834
            SAL: Sala_0114
            GOX: GOX1705
            GBE: GbCGDNIH1_0854
            ACR: Acry_1276
            GDI: GDI_0287(gnd)
            GDJ: Gdia_2350
            APT: APA01_23130
            BSU: BSU23860(yqjI) BSU25730(yqeC) BSU40080(gntZ)
            BSS: BSUW23_11790(gndA) BSUW23_12775(yqeC) BSUW23_19985(gntZ)
            BHA: BH2674
            BAN: BA_0164(yqjI) BA_3431
            BAR: GBAA_0164(yqjI) GBAA_3431
            BAT: BAS0166 BAS3180
            BAH: BAMEG_0195(yqjI) BAMEG_1196
            BAI: BAA_0195(yqjI) BAA_3465(gnd)
            BAL: BACI_c02050(gntZ) BACI_c33330
            BCE: BC2225 BC3372
            BCA: BCE_2304(gnd) BCE_3410
            BCZ: BCZK0157(gnd) BCZK3081(gnd)
            BCR: BCAH187_A0208(yqjI) BCAH187_A3412
            BCB: BCB4264_A2255(gnd) BCB4264_A3387
            BCU: BCAH820_0186(yqjI) BCAH820_3400
            BCG: BCG9842_B1845 BCG9842_B3070(gnd)
            BCQ: BCQ_0188(gntZ) BCQ_3186(gnd)
            BCX: BCA_0207(yqjI) BCA_3467
            BCY: Bcer98_1665
            BTK: BT9727_0159(gntZ) BT9727_3164(gnd)
            BTL: BALH_0162(gntZ) BALH_3050
            BTB: BMB171_C2002(gnd) BMB171_C3062
            BWE: BcerKBAB4_2095 BcerKBAB4_3104
            BLI: BL00198(gntZ) BL01383(yqjI)
            BLD: BLi02567(yqjI) BLi04289(gntZ)
            BAY: RBAM_022170(yqjI)
            BAO: BAMF_2286(gndA)
            BAE: BATR1942_10240 BATR1942_18025
            BCL: ABC1926
            BPU: BPUM_2124(yqjI)
            BPF: BpOF4_01170
            BMQ: BMQ_0752(gnd) BMQ_1336(gnd) BMQ_3260(gnd) BMQ_5211(gnd)
            BMD: BMD_1316(gnd) BMD_3266(gnd) BMD_5197(gnd)
            BCO: Bcell_3669
            OIH: OB0185 OB3187(gntZ)
            GKA: GK2344
            GTN: GTNG_2289(gntZ)
            GWC: GWCH70_2279
            GYM: GYMC10_1905 GYMC10_6341
            GYC: GYMC61_0326
            GYA: GYMC52_2339
            GCT: GC56T3_1159
            GMC: GY4MC1_1224 GY4MC1_3101
            AFL: Aflv_0976
            SAU: SA1342(gnd)
            SAV: SAV1511(gnd)
            SAW: SAHV_1499(gnd)
            SAH: SaurJH1_1601 SaurJH1_2810
            SAJ: SaurJH9_1569 SaurJH9_2765
            SAM: MW1464(gnd)
            SAS: SAS1450
            SAR: SAR1589(gnd)
            SAC: SACOL1554(gnd)
            SAX: USA300HOU_1512(pgd)
            SAA: SAUSA300_1459(gnd)
            SAO: SAOUHSC_01605
            SAE: NWMN_1417(gnd)
            SAD: SAAV_1502
            SAB: SAB1384c(gnd)
            SEP: SE1192
            SER: SERP1071(gnd)
            SHA: SH1406(gnd)
            SSP: SSP1244
            SCA: Sca_1132(gnd)
            SLG: SLGD_01404
            SSD: SPSINT_1205
            LMO: lmo1376
            LMF: LMOf2365_1395(gnd)
            LMH: LMHCC_1194(gnd)
            LMC: Lm4b_01385
            LMN: LM5578_1517
            LMY: LM5923_1469
            LIN: lin1413
            LWE: lwe1392(gnd)
            LSG: lse_1293(gnd)
            LSP: Bsph_4720
            ESI: Exig_2998
            EAT: EAT1b_1206 EAT1b_1221
            MCL: MCCL_1157(gnd)
            BBE: BBR47_27330
            PJD: Pjdr2_3810
            PPY: PPE_02029 PPE_02966(gnd)
            PPM: PPSC2_c2264 PPSC2_c3347
            AAC: Aaci_1061 Aaci_2831
            LLA: L0046(gnd) L53699(gntZ)
            LLK: LLKF_0600(gnd) LLKF_2430(gntZ)
            LLC: LACR_0642 LACR_2497
            LLM: llmg_0586(gnd) llmg_2469(gntZ)
            SPN: SP_0375
            SPD: SPD_0343(gnd)
            SPR: spr0335(gnd)
            SPW: SPCG_0371(gnd)
            SPX: SPG_0341(gnd)
            SNE: SPN23F_03470(gnd)
            SPV: SPH_0482(gnd)
            SNM: SP70585_0446(gnd)
            SJJ: SPJ_0361(gnd)
            SPP: SPP_0413(gnd)
            SNT: SPT_0418(gnd)
            SNC: HMPREF0837_10672(gnd)
            SNB: SP670_0443(gnd)
            SNP: SPAP_0400
            SSA: SSA_1811(gnd)
            SSU: SSU05_1733 SSU05_1735
            SSV: SSU98_1745
            SSB: SSUBM407_1615(gnd)
            SSI: SSU1541(gnd)
            SSS: SSUSC84_1567(gnd)
            SGO: SGO_0503(gnd)
            SUB: SUB0199
            SMB: smi_1750(gnd)
            LPL: lp_1251(gnd1) lp_1541(gnd2)
            LPJ: JDM1_1059(gnd1) JDM1_1292(gnd2)
            LPS: LPST_C1015(gnd1) LPST_C1216(gnd2)
            LJO: LJ1852
            LJF: FI9785_1804(gnd)
            LAC: LBA1973
            LSA: LSA0297(gntZ) LSA1385(gndA)
            LSL: LSL_0645(gnd)
            LDB: Ldb2212(gnd)
            LBU: LBUL_2033
            LDE: LDBND_2050(gnd)
            LBR: LVIS_0094 LVIS_0144
            LCA: LSEI_0227 LSEI_1681
            LCB: LCABL_02270(gntZ) LCABL_18990(gndA)
            LCZ: LCAZH_0262 LCAZH_1670
            LGA: LGAS_1892
            LRE: Lreu_1766
            LRF: LAR_1654
            LHE: lhv_2102
            LFE: LAF_1761
            LRH: LGG_00274(gnd) LGG_01727(gnd)
            LRL: LC705_00265(gnd) LC705_01710(gnd)
            LCR: LCRIS_02017(gnd)
            LAM: LA2_10760
            PPE: PEPE_0713 PEPE_1362
            EFA: EF1049(gnd) EF3142
            OOE: OEOE_0892 OEOE_1523
            LME: LEUM_0551 LEUM_0924
            LCI: LCK_00462(gntZ) LCK_00929(gnd)
            LKI: LKI_00915 LKI_02715
            LGS: LEGAS_0931(gnd2) LEGAS_1343(gnd1)
            CTC: CTC01865
            CBK: CLL_A1312(gnd)
            CBE: Cbei_2192
            CLJ: CLJU_c11590
            AMT: Amet_3469
            DAE: Dtox_1550
            TTE: TTE0195(gnd) TTE1941(gnd2)
            TEX: Teth514_0139 Teth514_1081 Teth514_1416
            TPD: Teth39_0598 Teth39_0975 Teth39_2063
            TIT: Thit_0172 Thit_0964 Thit_1743
            TMT: Tmath_0229 Tmath_1019 Tmath_1723
            TBO: Thebr_0615 Thebr_1001 Thebr_2108
            MTA: Moth_1283
            TOC: Toce_1896
            TTM: Tthe_2388 Tthe_2465
            HOR: Hore_16280
            HAS: Halsa_0820
            MCP: MCAP_0460
            MLC: MSB_A0473(gnd)
            ACL: ACL_0963(gnd)
            MTU: Rv1122(gnd2) Rv1844c(gnd1)
            MTC: MT1154 MT1892(gnd)
            MRA: MRA_1131(gnd2) MRA_1855(gnd1)
            MTF: TBFG_11145 TBFG_11872
            MTB: TBMG_02150(TBMG_02150.1) TBMG_02860(TBMG_02860.1)
            MBO: Mb1153(gnd2) Mb1875c(gnd1)
            MBB: BCG_1183(gnd2) BCG_1880c(gnd1)
            MBT: JTY_1156(gnd2) JTY_1864(gnd1)
            MLE: ML2065(gnd)
            MLB: MLBr_02065(gnd)
            MPA: MAP1557c(gnd) MAP2670c(gnd2)
            MAV: MAV_1253(gnd) MAV_2871(gnd)
            MSM: MSMEG_0002 MSMEG_3632(gnd)
            MUL: MUL_0148(gnd2) MUL_3035(gnd1)
            MVA: Mvan_0003 Mvan_3089
            MGI: Mflv_0825 Mflv_3359
            MAB: MAB_0003(gnd) MAB_2413c
            MMC: Mmcs_0003 Mmcs_2812
            MKM: Mkms_0011 Mkms_2856
            MJL: Mjls_0003 Mjls_2839
            MSP: Mspyr1_00030 Mspyr1_26900
            MMI: MMAR_2718(gnd1) MMAR_4338(gnd2)
            CGL: NCgl1396(cgl1452)
            CGB: cg1643(gnd)
            CGT: cgR_1513
            CEF: CE1588
            CDI: DIP1213(gnd)
            CJK: jk0912(gnd)
            CUR: cur_1065
            CAR: cauri_1296(gnd)
            CKP: ckrop_0877(gnd)
            CPU: cpfrc_01011(gnd)
            NFA: nfa11750(gnd) nfa54570(gnd2)
            RHA: RHA1_ro00556(gnd1) RHA1_ro03668(gnd2) RHA1_ro07246(gnd3)
                 RHA1_ro11061(gnd4) RHA1_ro11328(gnd5)
            RER: RER_00030 RER_31010(gnd)
            ROP: ROP_34850 ROP_70300(gnd)
            REQ: REQ_00030 REQ_24220
            GBR: Gbro_2762
            TPR: Tpau_0004 Tpau_1596
            SRT: Srot_1784
            SCO: SCO0975(SCBAC19F3.02) SCO3877(SCH18.14c) SCO6658(SC5A7.08c)
            SMA: SAV_1771(gnd1) SAV_4318(gnd2) SAV_7249(gnd3)
            SGR: SGR_3702 SGR_769
            SCB: SCAB_11811 SCAB_15751 SCAB_45801
            TWH: TWT492(gnd)
            TWS: TW272(gnd)
            LXX: Lxx00030(gnd) Lxx17380(gnd)
            CMI: CMM_0003(gndA1) CMM_2272(gndA2)
            CMS: CMS_0004 CMS_2466(gnd)
            ART: Arth_0003 Arth_2449
            AAU: AAur_0003 AAur_2419(gnd)
            ACH: Achl_0003 Achl_2197
            AAI: AARI_15520(gnd)
            RSA: RSal33209_0003 RSal33209_3326
            KRH: KRH_14660(gnd)
            MLU: Mlut_09430
            RMU: RMDY18_07920
            RDN: HMPREF0733_12158(gnd)
            BCV: Bcav_0003 Bcav_3598
            BFA: Bfae_07950
            JDE: Jden_1948
            KSE: Ksed_00030
            XCE: Xcel_0003 Xcel_1889
            SKE: Sked_00030 Sked_16410
            CFL: Cfla_0003 Cfla_1729
            ICA: Intca_0003 Intca_2469
            PAC: PPA1629
            PAK: HMPREF0675_4667(gnd)
            PFR: PFREUD_04620(gnd1) PFREUD_08090(gnd2)
            NCA: Noca_0003
            KFL: Kfla_0003 Kfla_1879
            TFU: Tfu_0003
            NDA: Ndas_0003
            TCU: Tcur_0003 Tcur_2816
            SRO: Sros_0004 Sros_3959
            FRA: Francci3_0936
            FRE: Franean1_5606
            FRI: FraEuI1c_1222
            FAL: FRAAL1567(gnd)
            ACE: Acel_1820
            NML: Namu_0003 Namu_4562 Namu_4789
            GOB: Gobs_0003
            KRA: Krad_0003 Krad_1524
            SEN: SACE_0004(gnd2) SACE_4396(zwf3)
            SVI: Svir_00030 Svir_36670
            TBI: Tbis_0003 Tbis_2102
            AMD: AMED_0003(gnd) AMED_0394(gnd)
            AMI: Amir_0003 Amir_5683
            STP: Strop_0004 Strop_3445
            SAQ: Sare_0003 Sare_3824
            MAU: Micau_0003 Micau_4835
            MIL: ML5_0003 ML5_3464
            CAI: Caci_0003 Caci_1141 Caci_2642
            SNA: Snas_0003
            MCU: HMPREF0573_10630(yqjI)
            BLO: BL0444(gnt)
            BLJ: BLD_1244(gnd)
            BLN: Blon_0207
            BLL: BLJ_0210
            BLB: BBMN68_1188(gnd)
            BAD: BAD_0197 BAD_0628(gnt)
            BLA: BLA_1007(gnd)
            BLC: Balac_1041
            BLT: Balat_1041
            BDE: BDP_0295(gnt) BDP_0847(gnt)
            BBI: BBIF_1443(gnt)
            BBP: BBPR_1497(gnt)
            GVA: HMPREF0424_0180(gnd)
            GVG: HMPREF0421_20299(gnd) HMPREF0421_21329(gnd2)
            RXY: Rxyl_0050
            CWO: Cwoe_2511 Cwoe_4301
            AFO: Afer_1093
            CTR: CT063(gnd)
            CTA: CTA_0068(gnd)
            CTB: CTL0319(gnd)
            CTL: CTLon_0314(gnd)
            CTJ: JALI_0621(gnd)
            CTZ: CTB_0621(gnd)
            CMU: TC0333(pgd)
            CPN: CPn0360(gnd)
            CPA: CP0398
            CPJ: CPj0360(gnd)
            CPT: CpB0369
            CCA: CCA00432(gnd)
            CAB: CAB418(gnd)
            CFE: CF0576(gnd)
            PCU: pc0317(pgd)
            WCH: wcw_0356(gnd)
            BBU: BB0561
            BBZ: BbuZS7_0571(gnd)
            BGA: BG0571(gnd)
            BAF: BAPKO_0590(gnd)
            BTU: BT0561
            BHR: BH0561
            BDU: BDU_563(gnd)
            BRE: BRE_566(gnd)
            TPA: TP0331
            TPP: TPASS_0331(gnd)
            SSM: Spirs_3595
            ABA: Acid345_2811
            ACA: ACP_2279(gnd)
            TSA: AciPR4_0514 AciPR4_0849
            SUS: Acid_1206 Acid_7082
            BTH: BT_1222
            BFR: BF1853
            BFS: BF1919(gnd)
            BVU: BVU_2795
            BHL: Bache_2720
            PDI: BDI_0646
            PPN: Palpr_0566
            SRU: SRU_0079(gnd)
            SRM: SRM_00084(gnd)
            RMR: Rmar_2300
            CHU: CHU_1404(gnd)
            DFE: Dfer_5181
            SLI: Slin_4083 Slin_6630
            CPI: Cpin_1480
            PHE: Phep_1676 Phep_2404
            FJO: Fjoh_4799
            RBI: RB2501_00246
            ZPR: ZPR_2641
            FBC: FB2170_13818
            CAO: Celal_0076
            IPO: Ilyop_2788
            OTE: Oter_0758
            CAA: Caka_2080
            MIN: Minf_0198(gnd)
            RBA: RB2817(6pgD)
            PSL: Psta_2486
            PLM: Plim_2297
            IPA: Isop_3207
            SYN: sll0329(gnd)
            SYW: SYNW1119(gnd)
            SYC: syc1460_c(gnd)
            SYF: Synpcc7942_0039
            SYD: Syncc9605_1256
            SYE: Syncc9902_1226
            SYG: sync_1688(gnd)
            SYR: SynRCC307_1252(gnd)
            SYX: SynWH7803_1297(gnd)
            SYP: SYNPCC7002_A0221(gnd)
            CYA: CYA_0947(gnd)
            CYB: CYB_2481(gnd)
            TEL: tlr0576
            MAR: MAE_15220
            CYT: cce_3746(gnd)
            CYP: PCC8801_2258
            CYC: PCC7424_3297
            CYN: Cyan7425_1582
            CYH: Cyan8802_2309
            CYJ: Cyan7822_3017
            CYU: UCYN_06970
            GVI: gll1117
            ANA: alr5275
            NPU: Npun_F2977 Npun_F3303 Npun_R6307
            AVA: Ava_2527 Ava_C0152
            NAZ: Aazo_1275
            PMA: Pro0843(gnd)
            PMM: PMM0770(gnd)
            PMT: PMT0565(gnd)
            PMN: PMN2A_0176
            PMI: PMT9312_0778
            PMB: A9601_08321(gnd)
            PMC: P9515_08131(gnd)
            PMF: P9303_16871(gnd)
            PMG: P9301_08301(gnd)
            PMH: P9215_08641(gnd)
            PMJ: P9211_09921(gnd)
            PME: NATL1_08081(gnd)
            TER: Tery_1834
            AMR: AM1_2091(gnd) AM1_6319(gnd)
            CTE: CT1874
            CPC: Cpar_0334
            CCH: Cag_1669
            CPH: Cpha266_2151
            CPB: Cphamn1_2105
            CLI: Clim_2077
            PVI: Cvib_0374
            PLT: Plut_0306
            PPH: Ppha_2484
            PAA: Paes_1907
            DLY: Dehly_0889
            RRS: RoseRS_4286
            RCA: Rcas_0935
            CAU: Caur_0500
            CAG: Cagg_3189
            CHL: Chy400_0536
            HAU: Haur_2625
            TRO: trd_1142(gnd)
            STI: Sthe_2435
            ATM: ANT_01430(gnd)
            DRA: DR_1595
            DGE: Dgeo_1973
            DDR: Deide_16450(gnd)
            DMR: Deima_2378
            TRA: Trad_1523 Trad_1969
            TSC: TSC_c11220
            MSV: Mesil_2478
            AAE: aq_498(gnd)
            HYA: HY04AAS1_1281
            HTH: HTH_0380(gnd)
            TAL: Thal_1580
            TMA: TM0438
            TPT: Tpet_0482
            TLE: Tlet_0874
            TRQ: TRQ2_0497
            TNA: CTN_0234
            TNP: Tnap_0220
            PMO: Pmob_0443
            DTH: DICTH_1926(gnd)
            DTU: Dtur_0197
            NDE: NIDE2204(gnd)
            TTR: Tter_0833
            MPD: MCP_2266
            HAL: VNG2553G(yqeC)
            HSL: OE4581F(gnd)
            HMA: rrnAC2180(gnd)
            HWA: HQ1075A(gnd)
            NPH: NP0286A(gnd)
            HLA: Hlac_1605
            HMU: Hmuk_0410
            HTU: Htur_3388
            NMG: Nmag_1339
            HVO: HVO_1830(gndA)
            HJE: HacjB3_14780
            HBO: Hbor_03760
            RCI: RCIX2363(gnd)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.44
            IUBMB Enzyme Nomenclature: 1.1.1.44
            ExPASy - ENZYME nomenclature database: 1.1.1.44
            BRENDA, the Enzyme Database: 1.1.1.44
            CAS: 9073-95-4
///
ENTRY       EC 1.1.1.45                 Enzyme
NAME        L-gulonate 3-dehydrogenase;
            L-3-aldonate dehydrogenase;
            L-3-aldonic dehydrogenase;
            L-gulonic acid dehydrogenase;
            L-beta-hydroxyacid dehydrogenase;
            L-beta-hydroxy-acid-NAD+-oxidoreductase;
            L-3-hydroxyacid dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-gulonate:NAD+ 3-oxidoreductase
REACTION    L-gulonate + NAD+ = 3-dehydro-L-gulonate + NADH + H+ [RN:R02640]
ALL_REAC    R02640
SUBSTRATE   L-gulonate [CPD:C00800];
            NAD+ [CPD:C00003]
PRODUCT     3-dehydro-L-gulonate [CPD:C00618];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also oxidizes other L-3-hydroxyacids.
REFERENCE   1
  AUTHORS   Dworsky, P. and Hoffmann-Ostenhof, O.
  TITLE     L-3-Aldonic acid dehydrogenase from Schwanniomyces occidentalis.
  JOURNAL   Acta Biochim. Pol. 11 (1964) 269-277.
REFERENCE   2
  AUTHORS   Smiley, J.D. and Ashwell, G.
  TITLE     Purification and properties of beta-L-hydroxy acid dehydrogenase.
            II. Isolation of beta-keto-L-gluconic acid, an intermediate in
            L-xylulose biosynthesis.
  JOURNAL   J. Biol. Chem. 236 (1961) 357-364.
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec01100  Metabolic pathways
ORTHOLOGY   K13247  L-gulonate 3-dehydrogenase
GENES       HSA: 51084(CRYL1)
            PTR: 452458(CRYL1)
            PON: 100171829(CRYL1)
            MCC: 703988(CRYL1)
            MMU: 68631(Cryl1)
            RNO: 290277(Cryl1)
            CFA: 486050(CRYL1)
            AML: 100472061
            BTA: 281725(CRYL1)
            SSC: 396914(CRY)
            ECB: 100054141
            OAA: 100089465
            GGA: 418953(CRYL1)
            TGU: 100232047
            XLA: 100036971(cryl1)
            XTR: 100145620(cryl1)
            DRE: 751596(cryl1)
            BFO: BRAFLDRAFT_116612
            CIN: 100176260
            SPU: 589657
            DME: Dmel_CG10131 Dmel_CG9914
            DPO: Dpse_GA10097 Dpse_GA23040
            DAN: Dana_GF11336 Dana_GF19071
            DER: Dere_GG19334 Dere_GG20470
            DPE: Dper_GL11451 Dper_GL21343
            DSE: Dsec_GM13412 Dsec_GM21560
            DSI: Dsim_GD11066
            DWI: Dwil_GK19629 Dwil_GK25055
            DYA: Dyak_GE11007 Dyak_GE13601
            DGR: Dgri_GH12278 Dgri_GH22921
            DMO: Dmoj_GI10976 Dmoj_GI18410
            DVI: Dvir_GJ18534 Dvir_GJ21492
            AAG: AaeL_AAEL008006
            CQU: CpipJ_CPIJ019115
            AME: 406119(Cryl1)
            NVI: 100116345(NV13246)
            TCA: 656318
            API: 100160442
            PHU: Phum_PHUM424710
            ISC: IscW_ISCW024631
            CEL: Y71F9B.9
            CBR: CBG04121
            NVE: NEMVE_v1g168735
            HMG: 100202070
            MBR: MONBRDRAFT_2035
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.45
            IUBMB Enzyme Nomenclature: 1.1.1.45
            ExPASy - ENZYME nomenclature database: 1.1.1.45
            BRENDA, the Enzyme Database: 1.1.1.45
            CAS: 9028-51-7
///
ENTRY       EC 1.1.1.46                 Enzyme
NAME        L-arabinose 1-dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     L-arabinose:NAD+ 1-oxidoreductase
REACTION    L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH + H+ [RN:R01757]
ALL_REAC    R01757
SUBSTRATE   L-arabinose [CPD:C00259];
            NAD+ [CPD:C00003]
PRODUCT     L-arabinono-1,4-lactone [CPD:C01114];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13271422]
  AUTHORS   WEIMBERG R, DOUDOROFF M.
  TITLE     The oxidation of L-arabinose by Pseudomonas saccharophila.
  JOURNAL   J. Biol. Chem. 217 (1955) 607-24.
  ORGANISM  Pseudomonas saccharophila
PATHWAY     ec00053  Ascorbate and aldarate metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K13873  L-arabinose 1- dehydrogenase
GENES       RPI: Rpic_3007
            RPF: Rpic12D_2597
            BTE: BTH_II1629
            BVI: Bcep1808_3835
            BUR: Bcep18194_B0043
            BCN: Bcen_5217
            BCH: Bcen2424_5642
            BCM: Bcenmc03_4587
            BCJ: BCAM2799(gal)
            BAM: Bamb_4922
            BAC: BamMC406_5477
            BMU: Bmul_3205
            BMJ: BMULJ_05320(gal)
            BPH: Bphy_4216
            BGL: bglu_1g17840
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.46
            IUBMB Enzyme Nomenclature: 1.1.1.46
            ExPASy - ENZYME nomenclature database: 1.1.1.46
            BRENDA, the Enzyme Database: 1.1.1.46
            CAS: 9028-52-8
///
ENTRY       EC 1.1.1.47                 Enzyme
NAME        glucose 1-dehydrogenase;
            D-glucose dehydrogenase (NAD(P)+);
            hexose phosphate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     beta-D-glucose:NAD(P)+ 1-oxidoreductase
REACTION    beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H + H+
            [RN:R01520 R01521]
ALL_REAC    R01520 R01521
SUBSTRATE   beta-D-glucose [CPD:C00221];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     D-glucono-1,5-lactone [CPD:C00198];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also oxidizes D-xylose.
REFERENCE   1  [PMID:810982]
  AUTHORS   Banauch D, Brummer W, Ebeling W, Metz H, Rindfrey H, Lang H, Leybold
            K, Rick W, Staudinger HJ.
  TITLE     [A glucose dehydrogenase for the determination of glucose
            concentrations in body fluids (author's transl)]
  JOURNAL   Z. Klin. Chem. Klin. Biochem. 13 (1975) 101-7.
  ORGANISM  Bacillus megaterium
REFERENCE   2
  AUTHORS   Brink, N.G.
  TITLE     Beef liver glucose dehydrogenase. 1. Purification and properties.
  JOURNAL   Acta Chem. Scand. 7 (1953) 1081-1089.
REFERENCE   3
  AUTHORS   Pauly, H.E. and Pfleiderer, G.
  TITLE     D-Glucose dehydrogenase from Bacillus megaterium M 1286:
            purification, properties and structure.
  JOURNAL   Hoppe-Seyler's Z. Physiol. Chem. 356 (1976) 1613-1623.
REFERENCE   4  [PMID:12981017]
  AUTHORS   STRECKER HJ, KORKES S.
  TITLE     Glucose dehydrogenase.
  JOURNAL   J. Biol. Chem. 196 (1952) 769-84.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   5  [PMID:4392298]
  AUTHORS   Thompson RE, Carper WR.
  TITLE     Glucose dehydrogenase from pig liver. I. Isolation and purification.
  JOURNAL   Biochim. Biophys. Acta. 198 (1970) 397-406.
  ORGANISM  Sus scofa [GN:ssc]
PATHWAY     ec00030  Pentose phosphate pathway
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00034  glucose 1-dehydrogenase
            K13937  hexose-6-phosphate dehydrogenase
GENES       HSA: 9563(H6PD)
            PON: 100438428
            MCC: 710107(H6PD)
            MMU: 100198(H6pd)
            RNO: 298655(H6pd)
            CFA: 489642(H6PD)
            AML: 100476557(H6PD)
            BTA: 541220(H6PD)
            ECB: 100057646(H6PD)
            MDO: 100009940
            OAA: 100082409
            GGA: 428188(H6PD)
            TGU: 100228049(H6PD)
            XTR: 100127695(h6pd)
            DRE: 569348
            BFO: BRAFLDRAFT_65130
            SPU: 590387
            NVE: NEMVE_v1g31531
            TAD: TRIADDRAFT_20384
            ETA: ETA_30410(gdh)
            EPY: EpC_32460(gdh)
            EAM: EAMY_3245(gdh)
            EAY: EAM_0356(gdh)
            PMR: PMI1532
            PST: PSPTO_2492
            PSB: Psyr_2297
            PSP: PSPPH_2879
            PFL: PFL_4100
            PFO: Pfl01_1840
            PFS: PFLU2089
            PSA: PST_3895
            NWA: Nwat_1326
            AFE: Lferr_1535 Lferr_1879
            AFR: AFE_1857 AFE_2225
            BMU: Bmul_0907
            BMJ: BMULJ_02351(gdh)
            BXE: Bxe_B0443
            BPH: Bphy_4761
            BPY: Bphyt_7232
            BGE: BC1002_4763
            BPT: Bpet0388(gdh)
            AXY: AXYL_03471
            AAV: Aave_1089
            TBD: Tbd_0924
            SCL: sce7442
            HOH: Hoch_0357
            BJA: bll7157 bll7185(gdh)
            BRA: BRADO1396
            BBT: BBta_6708
            MPO: Mpop_1521
            RDE: RD1_3328
            SWI: Swit_0697
            GOX: GOX2015
            ACR: Acry_2603 Acry_3136
            GDI: GDI_2625(gdh)
            GDJ: Gdia_0840
            BSU: BSU02830(ycdF) BSU03930(gdh)
            BSS: BSUW23_02030(gdh)
            BAN: BA_4968(gdh)
            BAR: GBAA_4968(gdh)
            BAT: BAS4612
            BAH: BAMEG_4999(gdh)
            BAI: BAA_4978(gdh)
            BCE: BC4715
            BCA: BCE_4858(gdh)
            BCZ: BCZK4466(gdh) pE33L466_0368(gdh)
            BCR: BCAH187_A4852(gdh)
            BCB: BCB4264_A4828(gdh)
            BCU: BCAH820_4834(gdh)
            BCG: BCG9842_B0408(gdh)
            BCQ: BCQ_4529(gdh)
            BCX: BCA_4839(gdh)
            BCY: Bcer98_3132
            BTK: BT9727_4448(gdh)
            BTL: BALH_3120 BALH_4289(gdh)
            BTB: BMB171_C4353(gdh)
            BWE: BcerKBAB4_4547
            BLI: BL01382(gdh) BL01687(ycdF)
            BLD: BLi00341(ycdF) BLi02566(gdh)
            BAY: RBAM_003090(ycdF) RBAM_004180(gdh)
            BAO: BAMF_0361(gdh)
            BAE: BATR1942_20675
            BPU: BPUM_0257(ycdF) BPUM_2122(gdh)
            BMQ: BMQ_0838(gdh) BMQ_1051 BMQ_3371
            BMD: BMD_0838(gdh) BMD_1054 BMD_3374
            OIH: OB3183
            SAA: SAUSA300_2416
            SEP: SE1830
            SER: SERP1839(gdh)
            SHA: SH0795
            SSP: SSP0656
            SCA: Sca_1743(gdh)
            ESI: Exig_0211
            EAT: EAT1b_1955
            MCL: MCCL_0186 MCCL_1630
            PJD: Pjdr2_4221
            LAC: LBA1098
            LSL: LSL_0144(gdh)
            LCA: LSEI_2180
            LCB: LCABL_23550(gdh)
            LRH: LGG_02189(gdh)
            LRL: LC705_02185(gdh)
            PPE: PEPE_0073
            EFA: EF2382(gdh)
            SCO: SCO1335(2SCG61.17c)
            SMA: SAV_1922(gdh)
            FRA: Francci3_2849
            NML: Namu_1837
            STP: Strop_0661
            SAQ: Sare_0635
            RXY: Rxyl_0551
            CWO: Cwoe_1554
            ELE: Elen_0198
            WCH: wcw_0442
            ABA: Acid345_3509
            ACA: ACP_3015(gdh)
            SUS: Acid_2336 Acid_7577
            CHU: CHU_1661(gdh)
            DFE: Dfer_1228
            SLI: Slin_2520
            CPI: Cpin_0947
            ZPR: ZPR_1651
            OTE: Oter_3349
            RBA: RB7294(gdh)
            PSL: Psta_3574
            SYN: sll1709(gdh)
            SYC: syc0030_d
            SYF: Synpcc7942_1573
            SYG: sync_1918
            SYR: SynRCC307_1928(gdh)
            SYX: SynWH7803_0725(gdh)
            CYT: cce_0222
            CYC: PCC7424_3932
            CYN: Cyan7425_1811 Cyan7425_4436
            CYJ: Cyan7822_5687 Cyan7822_6114
            GVI: gll1114
            ANA: all3836
            NPU: Npun_F1792 Npun_F2211
            AVA: Ava_1863
            TTR: Tter_2119
            HMA: rrnAC2741(ywfD2)
            TAC: Ta0897
            TVO: TVN1019
            PTO: PTO0639 PTO1070
            PHO: PH1809
            PFU: PF1853
            TKO: TK0673
            HBU: Hbut_1375
            SSO: SSO3003(dhg-1) SSO3042(dhg-2) SSO3204(dhg-3)
            STO: ST1704
            SAI: Saci_1079
            SIS: LS215_2319
            SIA: M1425_2156
            SIM: M1627_2236
            SID: M164_2160
            SIY: YG5714_2283
            SIN: YN1551_0633
            SII: LD85_2423
            MSE: Msed_1301
            CMA: Cmaq_1714
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.47
            IUBMB Enzyme Nomenclature: 1.1.1.47
            ExPASy - ENZYME nomenclature database: 1.1.1.47
            BRENDA, the Enzyme Database: 1.1.1.47
            CAS: 9028-53-9
///
ENTRY       EC 1.1.1.48                 Enzyme
NAME        galactose 1-dehydrogenase;
            D-galactose dehydrogenase;
            beta-galactose dehydrogenase;
            NAD+-dependent D-galactose dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-galactose:NAD+ 1-oxidoreductase
REACTION    D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+ [RN:R01094]
ALL_REAC    R01094;
            (other) R01096 R01097 R08544
SUBSTRATE   D-galactose [CPD:C00124];
            NAD+ [CPD:C00003]
PRODUCT     D-galactono-1,4-lactone [CPD:C03383];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13462997]
  AUTHORS   DE LEY J, DOUDOROFF M.
  TITLE     The metabolism of D-galactose in Pseudomonas saccharophila.
  JOURNAL   J. Biol. Chem. 227 (1957) 745-57.
  ORGANISM  Pseudomonas saccharophila
REFERENCE   2  [PMID:14251301]
  AUTHORS   HU AS, CLINE AL.
  TITLE     THE REGULATION OF SOME SUGAR DEHYDROGENASES IN A PSEUDOMONAD.
  JOURNAL   Biochim. Biophys. Acta. 93 (1964) 237-45.
  ORGANISM  Pseudomonas saccharophila
PATHWAY     ec00052  Galactose metabolism
ORTHOLOGY   K00035  D-galactose 1-dehydrogenase
GENES       XCC: XCC0744(dgd)
            XCB: XC_3491
            XCA: xccb100_3611
            XCV: XCV0847
            XAC: XAC0797(dgd)
            XOO: XOO3804(dgd)
            XOM: XOO_3586
            XOP: PXO_04345
            PSU: Psesu_0880
            PST: PSPTO_4782(gal)
            PSB: Psyr_4331
            PSP: PSPPH_4371(gal)
            CSA: Csal_1017
            HEL: HELO_2796(gal)
            HSE: Hsero_2708
            MLO: mll0280
            MCI: Mesci_3619
            MES: Meso_0843
            SME: SMc00588(gal)
            SMD: Smed_0768
            RHI: NGR_c09060
            ATU: Atu1113
            ARA: Arad_1691(gal)
            AVI: Avi_3910
            RET: RHE_CH01458(gal)
            REC: RHECIAT_CH0001526(gal)
            RLE: RL1574
            RLT: Rleg2_1072
            RLG: Rleg_1217
            BME: BMEII0355
            BMI: BMEA_B0926
            BMF: BAB2_0293
            BMB: BruAb2_0292
            BMC: BAbS19_II02780
            BMS: BRA0941
            BMT: BSUIS_B0934
            BOV: BOV_A0883
            BCS: BCAN_B0961(gal)
            BMR: BMI_II935
            OAN: Oant_1420
            BJA: blr3205
            BRA: BRADO1814
            BBT: BBta_2134
            SNO: Snov_0117
            MRD: Mrad2831_1330
            MET: M446_4632
            BID: Bind_3077
            CCR: CC_0967
            CCS: CCNA_01018
            CAK: Caul_3616 Caul_3971
            CSE: Cseg_1896 Cseg_3324
            AEX: Astex_1898
            PDE: Pden_4245
            SAL: Sala_0745
            SJP: SJA_C1-05950
            AZL: AZL_e03690(gal)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.48
            IUBMB Enzyme Nomenclature: 1.1.1.48
            ExPASy - ENZYME nomenclature database: 1.1.1.48
            BRENDA, the Enzyme Database: 1.1.1.48
            CAS: 9028-54-0
///
ENTRY       EC 1.1.1.49                 Enzyme
NAME        glucose-6-phosphate dehydrogenase;
            NADP-glucose-6-phosphate dehydrogenase;
            Zwischenferment;
            D-glucose 6-phosphate dehydrogenase;
            glucose 6-phosphate dehydrogenase (NADP);
            NADP-dependent glucose 6-phosphate dehydrogenase;
            6-phosphoglucose dehydrogenase;
            Entner-Doudoroff enzyme;
            glucose-6-phosphate 1-dehydrogenase;
            G6PDH;
            GPD
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-glucose-6-phosphate:NADP+ 1-oxidoreductase
REACTION    D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone +
            NADPH + H+ [RN:R00835]
ALL_REAC    R00835 > R02736
SUBSTRATE   D-glucose 6-phosphate [CPD:C00092];
            NADP+ [CPD:C00006]
PRODUCT     6-phospho-D-glucono-1,5-lactone [CPD:C01236];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
INHIBITOR   Fatty acid [CPD:C00162]
COMMENT     Also acts slowly on beta-D-glucose and other sugars. Certain
            preparations reduce NAD+ as well as NADP+.
REFERENCE   1  [PMID:5363983]
  AUTHORS   Engel HJ, Domschke W, Alberti M, Domagk GF.
  TITLE     Protein structure and enzymatic activity. II. Purification and
            properties of a crystalline glucose-6-phosphate dehydrogenase from
            Candida utilis.
  JOURNAL   Biochim. Biophys. Acta. 191 (1969) 509-16.
  ORGANISM  Candida utilis
REFERENCE   2  [PMID:13252007]
  AUTHORS   GLASER L, BROWN DH.
  TITLE     Purification and properties of d-glucose-6-phosphate dehydrogenase.
  JOURNAL   J. Biol. Chem. 216 (1955) 67-79.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
REFERENCE   3  [PMID:13790996]
  AUTHORS   JULIAN GR, WOLFE RG, REITHEL FJ.
  TITLE     The enzymes of mammary gland. II. The preparation of glucose
            6-phosphate dehydrogenase.
  JOURNAL   J. Biol. Chem. 236 (1961) 754-8.
  ORGANISM  Neurospora crassa [GN:ncr]
REFERENCE   4  [PMID:13729473]
  AUTHORS   NOLTMANN EA, GUBLER CJ, KUBY SA.
  TITLE     Glucose 6-phosphate dehydrogenase (Zwischenferment). I. Isolation of
            the crystalline enzyme from yeast.
  JOURNAL   J. Biol. Chem. 236 (1961) 1225-30.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
REFERENCE   5  [PMID:11457850]
  AUTHORS   Miclet E, Stoven V, Michels PA, Opperdoes FR, Lallemand JY, Duffieux
            F.
  TITLE     NMR spectroscopic analysis of the first two steps of the
            pentose-phosphate pathway elucidates the role of
            6-phosphogluconolactonase.
  JOURNAL   J. Biol. Chem. 276 (2001) 34840-6.
  ORGANISM  Homo sapiens [GN:hsa], Plasmodium falciparum, Trypanosoma brucei
            [GN:tbr]
PATHWAY     ec00030  Pentose phosphate pathway
            ec00480  Glutathione metabolism
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00036  glucose-6-phosphate 1-dehydrogenase
GENES       HSA: 2539(G6PD)
            PTR: 743041(G6PD)
            PON: 100449143
            MCC: 701137(G6PD)
            MMU: 14380(G6pd2) 14381(G6pdx)
            RNO: 24377(G6pd)
            CFA: 481088(G6PD)
            AML: 100469970
            BTA: 281179(G6PD)
            SSC: 100515002
            ECB: 100059734(G6PD)
            MDO: 100012365
            OAA: 100073461
            XLA: 379711(g6pd)
            XTR: 550066(g6pd)
            DRE: 100148915 570579(fj78b06)
            BFO: BRAFLDRAFT_276753
            CIN: 100183819
            SPU: 590603
            DME: Dmel_CG12529(Zw) Dmel_CG7140
            DPO: Dpse_GA11679 Dpse_GA28263
            DAN: Dana_GF20421 Dana_GF23498
            DER: Dere_GG13190 Dere_GG19245(Dere_Zw)
            DPE: Dper_GL18263 Dper_GL25454
            DSE: Dsec_GM22102 Dsec_GM22981(Dsec_Zw)
            DSI: Dsim_GD12078
            DWI: Dwil_GK12143 Dwil_GK20019
            DYA: Dyak_GE15864(Dyak_Zw) Dyak_GE19513
            DGR: Dgri_GH12489 Dgri_GH17134
            DMO: Dmoj_GI11107(Dmoj_G6pd) Dmoj_GI11743
            DVI: Dvir_GJ11415 Dvir_GJ15960
            AGA: AgaP_AGAP010739 AgaP_AGAP012678
            AAG: AaeL_AAEL009507
            CQU: CpipJ_CPIJ006761
            AME: 725325
            NVI: 100115674(Zw)
            TCA: 662934(G6pd)
            API: 100159375
            ISC: IscW_ISCW010043
            CEL: B0035.5
            CBR: CBG06072
            BMY: Bm1_36755
            SMM: Smp_052810
            NVE: NEMVE_v1g246951
            HMG: 100204193
            TAD: TRIADDRAFT_24087
            ATH: AT1G09420(G6PD4) AT1G24280(G6PD3) AT3G27300(G6PD5)
                 AT5G13110(G6PD2) AT5G35790(G6PD1) AT5G40760(G6PD6)
            POP: POPTR_554745 POPTR_641721 POPTR_708767 POPTR_736146
                 POPTR_807677 POPTR_834445
            RCU: RCOM_0347870 RCOM_1078990 RCOM_1436130
            VVI: 100254253 100254628 100264918 100266583 100267681
            OSA: 4329889 4332659 4333103 4336209 4342988
            SBI: SORBI_01g037060 SORBI_06g003160
            ZMA: 100279290(gpm175) 100284317 100304292 100383421(gpm742)
                 100383765
            PPP: PHYPADRAFT_106065 PHYPADRAFT_110277 PHYPADRAFT_110351
                 PHYPADRAFT_120050 PHYPADRAFT_179517 PHYPADRAFT_189728
                 PHYPADRAFT_209102 PHYPADRAFT_225940 PHYPADRAFT_233228
            CRE: CHLREDRAFT_119861(GLD1) CHLREDRAFT_173841(GLD2-N)
            VCN: VOLCADRAFT_82038
            OLU: OSTLU_45668
            OTA: Ot05g04760
            CME: CMI224C CMR014C
            SCE: YNL241C(ZWF1)
            AGO: AGOS_ABL206C
            KLA: KLLA0D19855g
            LTH: KLTH0H00374g
            PPA: PAS_chr2-1_0308
            VPO: Kpol_1015p12
            ZRO: ZYRO0F15686g
            CGR: CAGL0J07612g
            DHA: DEHA2C10274g
            PIC: PICST_85065(ZWF1)
            PGU: PGUG_03724
            LEL: LELG_00511
            CAL: CaO19.12218(ZWF1) CaO19.4754(ZWF1)
            CTP: CTRG_03250
            CDU: CD36_08460
            YLI: YALI0E22649g
            CLU: CLUG_01870
            NCR: NCU09111
            PAN: PODANSg5654
            MGR: MGG_09926(MG09926.4)
            FGR: FG01279.1
            SSL: SS1G_12886
            BFU: BC1G_08348
            ANI: AN2981.2
            AFM: AFUA_3G08470
            NFI: NFIA_068650
            AOR: AO090005001427
            ANG: An02g12140(gsdA)
            AFV: AFLA_086620
            ACT: ACLA_036450
            PCS: Pc20g03330
            CIM: CIMG_07661
            CPW: CPC735_042930
            URE: UREG_07624
            PNO: SNOG_09416
            TML: GSTUM_00008696001
            SPO: SPAC3A12.18(zwf1) SPAC3C7.13c SPCC794.01c
            CNE: CNG03280
            CNB: CNBG1480
            LBC: LACBIDRAFT_188936
            MPR: MPER_06249
            CCI: CC1G_00317
            SCM: SCHCODRAFT_12537
            UMA: UM04930.1
            MGL: MGL_3189
            ECU: ECU08_1850
            MBR: MONBRDRAFT_32291
            NGR: NAEGRDRAFT_78375
            DDI: DDB_G0273131(g6pd-1) DDB_G0273639(g6pd-2)
            PFA: PF14_0511
            PFD: PFDG_02252
            PFH: PFHG_00656
            PYO: PY00793
            PCB: PC000399.00.0
            PBE: PB001310.02.0
            PKN: PKH_125270
            PVX: PVX_117790
            TAN: TA05220
            TPV: TP03_0558
            BBO: BBOV_IV001600(21.m02735)
            TGO: TGME49_078830 TGME49_094200
            TBR: Tb10.70.5200
            TCR: 509287.50
            LMA: LmjF34.0080
            LIF: LinJ34.0080
            LBZ: LbrM20_V2.0160
            GLA: GL50803_8682
            TVA: TVAG_089600 TVAG_414060
            TPS: THAPSDRAFT_34514
            PIF: PITG_00146
            ECO: b1852(zwf)
            ECJ: JW1841(zwf)
            ECD: ECDH10B_1993(zwf)
            EBW: BWG_1666(zwf)
            ECE: Z2904(zwf)
            ECS: ECs2562
            ECF: ECH74115_2587(zwf)
            ETW: ECSP_2426(zwf)
            EOJ: ECO26_2690(zwf)
            EOI: ECO111_2360(zwf)
            EOH: ECO103_2042(zwf)
            ECG: E2348C_1977(zwf)
            EOK: G2583_2304(zwf)
            ECC: c2265(zwf)
            ECP: ECP_1796
            ECI: UTI89_C2055(zwf)
            ECV: APECO1_902(zwf)
            ECX: EcHS_A1944(zwf)
            ECW: EcE24377A_2082(zwf)
            ECM: EcSMS35_1335(zwf)
            ECY: ECSE_2027
            ECR: ECIAI1_1925(zwf)
            ECQ: ECED1_2057(zwf)
            ECK: EC55989_2030(zwf)
            ECT: ECIAI39_1198(zwf)
            EUM: ECUMN_2149(zwf)
            ECZ: ECS88_1909(zwf)
            ECL: EcolC_1780
            EBR: ECB_01823(zwf)
            EBD: ECBD_1787
            EFE: EFER_1221(zwf)
            STY: STY2094(zwf)
            STT: t0991(zwf)
            STM: STM1886(zwf)
            SPT: SPA0983(zwf)
            SEK: SSPA0917
            SPQ: SPAB_01282
            SEI: SPC_1830(zwf)
            SEC: SC1891(zwf)
            SEH: SeHA_C2100(zwf)
            SEE: SNSL254_A2045(zwf)
            SEW: SeSA_A2040(zwf)
            SEA: SeAg_B1238(zwf)
            SED: SeD_A1362(zwf)
            SEG: SG1166(zwf)
            SET: SEN1117(zwf)
            SES: SARI_01060
            YPE: YPO2066(zwf)
            YPK: y2244(zwf)
            YPA: YPA_1449
            YPN: YPN_1543
            YPM: YP_1909(zwf)
            YPP: YPDSF_1056
            YPG: YpAngola_A2412(zwf)
            YPZ: YPZ3_1758(zwf)
            YPS: YPTB2049(zwf)
            YPI: YpsIP31758_2022(zwf)
            YPY: YPK_2134
            YPB: YPTS_2109
            YEN: YE2383(zwf)
            SFX: S1928(zwf)
            SFV: SFV_1854(zwf)
            SSN: SSON_1296(zwf)
            SBO: SBO_1160(zwf)
            SBC: SbBS512_E2127(zwf)
            SDY: SDY_1138(zwf)
            ECA: ECA2479(zwf)
            PCT: PC1_1832
            PWA: Pecwa_2116
            ETA: ETA_14980(zwf)
            EPY: EpC_15740(zwf)
            EAM: EAMY_2054(zwf)
            EAY: EAM_1995(zwf)
            EBI: EbC_24960(zwf)
            PLU: plu2122(zwf)
            PAY: PAU_02443(zwf)
            BUC: BU320(zwf)
            BAS: BUsg312(zwf)
            BAB: bbp298(zwf)
            BCC: BCc_199(zwf)
            BAP: BUAP5A_313(zwf)
            BAU: BUAPTUC7_314(zwf)
            SGL: SG1270
            ENT: Ent638_2421
            ENC: ECL_01446
            ESC: Entcl_1938
            ESA: ESA_01389
            CTU: Ctu_25340(zwf)
            KPN: KPN_02367(zwf)
            KPE: KPK_1922(zwf)
            KPU: KP1_3496(zwf)
            KVA: Kvar_1742
            CKO: CKO_01113
            CRO: ROD_18921(zwf)
            SPE: Spro_2768
            PMR: PMI1157(zwf)
            EIC: NT01EI_1607
            ETR: ETAE_1449
            BFL: Bfl449(zwf)
            BPN: BPEN_464(zwf)
            BVA: BVAF_450(zwf)
            HDE: HDEF_0646(zwf)
            DDA: Dd703_2136
            DDC: Dd586_2187
            DDD: Dda3937_03574(zwf)
            DZE: Dd1591_2244
            XBO: XBJ1_2233(zwf)
            XNE: XNC1_2174(zwf)
            PAM: PANA_2191(zwf) PANA_4018(zwf2)
            PVA: Pvag_1655(zwf)
            PAO: Pat9b_2299
            HIN: HI0558(zwf)
            HIT: NTHI0686(zwf)
            HIP: CGSHiEE_00190
            HIQ: CGSHiGG_06065
            HIF: HIBPF17700
            HIL: HICON_08610
            HDU: HD0838(zwf)
            HAP: HAPS_0838(zwf)
            HSO: HS_1651(zwf)
            HSM: HSM_1813
            PMU: PM1549(zwf)
            MSU: MS0016(zwf)
            APL: APL_1311(zwf)
            APJ: APJL_1324(zwf)
            APA: APP7_1362
            ASU: Asuc_0227
            AAP: NT05HA_2091
            AAT: D11S_0516
            XFA: XF1065
            XFT: PD0346(zwf)
            XFM: Xfasm12_0374
            XFN: XfasM23_0338
            XCC: XCC2136(zwf) XCC3993(zwf)
            XCB: XC_1977 XC_4082
            XCA: xccb100_2042(zwf1) xccb100_4185(zwf2)
            XCV: XCV2237(zwf1) XCV4168(zwf2)
            XAC: XAC2071(zwf) XAC4081(zwf)
            XOO: XOO0467(zwf) XOO2314(zwf)
            XOM: XOO_0432 XOO_2191
            XOP: PXO_00608(zwf) PXO_02888(zwf)
            XAL: XALc_0145 XALc_1830(zwf)
            SML: Smlt1793(zwf)
            SMT: Smal_1531
            PSU: Psesu_1292
            VCH: VCA0896
            VCO: VC0395_0341(zwf)
            VCM: VCM66_A0856(zwf)
            VCJ: VCD_000435
            VVU: VV1_2684
            VVY: VV1605
            VVM: VVM_03171
            VPA: VP1710
            VHA: VIBHAR_02429
            VSP: VS_1304
            VEX: VEA_003323
            VFI: VF_A0468(zwf)
            VFM: VFMJ11_A0518(zwf)
            VSA: VSAL_II0687(zwf)
            PPR: PBPRA1442
            PAE: PA3183(zwf) PA5439
            PAU: PA14_23070(zwf) PA14_71800(zwf)
            PAP: PSPA7_1947(zwf2) PSPA7_6228(zwf1)
            PAG: PLES_18851(zwf) PLES_58341
            PPU: PP_1022(zwf-1) PP_4042(zwf-2) PP_5351(zwf-3)
            PPF: Pput_1060 Pput_1796 Pput_5259
            PPG: PputGB1_1020 PputGB1_3646 PputGB1_5400
            PPW: PputW619_1831 PputW619_4202 PputW619_5128
            PST: PSPTO_1300(zwf-1) PSPTO_3121(zwf-2)
            PSB: Psyr_1120 Psyr_2988
            PSP: PSPPH_1188(zwf1)
            PFL: PFL_3143(zwf) PFL_4610(zwf)
            PFO: Pfl01_2587 Pfl01_4363
            PFS: PFLU2692 PFLU4838
            PEN: PSEEN1940(zwf-2) PSEEN4405(zwf-1) PSEEN5500(zwf-3)
            PMY: Pmen_3143 Pmen_4486
            PSA: PST_0182(zwf-3) PST_2329 PST_3497
            CJA: CJA_1350(zwf)
            AVN: Avin_02020(zwf-4) Avin_27260(zwf-1)
            SON: SO_2489(zwf)
            SDN: Sden_2079
            SFR: Sfri_1892
            SAZ: Sama_1812
            SBL: Sbal_2241 Sbal_4527
            SBM: Shew185_2130
            SBN: Sbal195_2175
            SBP: Sbal223_2254
            SLO: Shew_2048
            SPC: Sputcn32_1866
            SSE: Ssed_2070
            SPL: Spea_2335
            SHE: Shewmr4_2046
            SHM: Shewmr7_1929
            SHN: Shewana3_2151
            SHW: Sputw3181_2142
            SHL: Shal_1949
            SWD: Swoo_2539
            SWP: swp_2390
            SVO: SVI_2317(zwf)
            CPS: CPS_2281(zwf)
            PHA: PSHAa1140(zwf)
            PAT: Patl_0970
            PSM: PSM_A1887(zwf)
            SDE: Sde_1380
            MAQ: Maqu_1834
            AMC: MADE_01244
            PIN: Ping_2754
            TTU: TERTU_2711(zwf)
            FBL: Fbal_1965
            LPN: lpg0416(zwf)
            LPF: lpl0459(zwf)
            LPP: lpp0483(zwf)
            LPC: LPC_2927(zwf)
            LPA: lpa_00651(zwf)
            LLO: LLO_2807(zwf)
            MCA: MCA0025(zwf-1) MCA2971(zwf-2)
            TCX: Tcr_1214
            NOC: Noc_0772 Noc_2062
            NHL: Nhal_2215 Nhal_2848
            NWA: Nwat_1038 Nwat_2337
            ALV: Alvin_2753
            TGR: Tgr7_0872
            HNA: Hneap_0996
            HCH: HCH_00347(zwf)
            CSA: Csal_2741
            HEL: HELO_3637(zwf)
            MMW: Mmwyl1_1038
            DNO: DNO_1223(zwf)
            AFE: Lferr_1690
            AFR: AFE_2025(zwf)
            BCI: BCI_0309(zwf)
            NMA: NMA1609(zwf)
            NME: NMB1392(zwf)
            NMC: NMC1331(zwf)
            NMN: NMCC_1307(zwf)
            NMI: NMO_1234(zwf)
            NGO: NGO0715
            NGK: NGK_1174
            NLA: NLA_9260(gdh)
            CVI: CV_0145(zwf)
            LHK: LHK_01919
            RSO: RSp1559(zwf)
            RSL: RPSI07_mp1663(zwf)
            RPI: Rpic_4867
            RPF: Rpic12D_3790
            REU: Reut_A1650 Reut_B5329
            REH: H16_A0316(zwf1) H16_B1501(zwf2) H16_B2566(zwf3)
            RME: Rmet_5801(zwf)
            CTI: RALTA_A0255(zwf1) RALTA_B2296(zwf2)
            BMA: BMA2130(zwf)
            BMV: BMASAVP1_A0780(zwf)
            BML: BMA10229_A2614(zwf)
            BMN: BMA10247_2000(zwf)
            BPS: BPSL2612(zwf)
            BPM: BURPS1710b_3087(zwf)
            BPL: BURPS1106A_3053(zwf)
            BPD: BURPS668_2999(zwf)
            BPR: GBP346_A3190(zwf)
            BTE: BTH_I1552(zwf)
            BVI: Bcep1808_0883 Bcep1808_3601
            BUR: Bcep18194_A4070 Bcep18194_B0242
            BCN: Bcen_0488 Bcen_5455
            BCH: Bcen2424_0967 Bcen2424_5407
            BCM: Bcenmc03_0928 Bcenmc03_4863
            BCJ: BCAL3042(zwf) BCAM2600(zwf)
            BAM: Bamb_0827 Bamb_4748
            BAC: BamMC406_0839 BamMC406_5293
            BMU: Bmul_2431 Bmul_3354
            BMJ: BMULJ_00802(zwf) BMULJ_05172(zwf)
            BXE: Bxe_A3452 Bxe_B0215 Bxe_B1764
            BPH: Bphy_0627 Bphy_2400 Bphy_3342
            BPY: Bphyt_1027 Bphyt_4908 Bphyt_7097
            BGL: bglu_1g08060 bglu_1g13030 bglu_2g11990
            BGE: BC1002_0742 BC1002_3729 BC1002_5019
            BRH: RBRH_01408 RBRH_03664
            RFR: Rfer_1125 Rfer_4034
            POL: Bpro_0751
            PNA: Pnap_0653 Pnap_3694
            AAV: Aave_0942
            AJS: Ajs_0695
            DIA: Dtpsy_0673
            VEI: Veis_4223
            DAC: Daci_5599
            VAP: Vapar_1096
            VPE: Varpa_1180
            HAR: HEAR1084(zwf)
            MMS: mma_2313(zwf)
            HSE: Hsero_1098(zwf)
            LCH: Lcho_3387
            TIN: Tint_1100
            NEU: NE0398(zwf)
            NET: Neut_2143 Neut_2431
            NMU: Nmul_A0466
            DAR: Daro_2070
            TBD: Tbd_2122
            MFA: Mfla_0917 Mfla_1061
            MMB: Mmol_1527
            MEH: M301_1112
            MEI: Msip34_1093
            MEP: MPQ_1148(zwf)
            SLT: Slit_0395
            GCA: Galf_1908
            HPY: HP1101
            HPJ: jhp1027(zwf)
            HPA: HPAG1_1039
            HPS: HPSH_05655
            HPG: HPG27_1042
            HPP: HPP12_1066
            HPB: HELPY_1070(zwf)
            HPL: HPB8_403(zwf)
            HPC: HPPC_05345
            HPM: HPSJM_05435
            HAC: Hac_0441
            HMS: HMU04960(zwf)
            HFE: Hfelis_04930(zwf)
            CJD: JJD26997_1270(zwf)
            ANT: Arnit_0214
            GME: Gmet_2619
            PCA: Pcar_0924(zwf)
            PPD: Ppro_2250
            DDE: Dde_3471
            DMA: DMR_05550(zwf)
            DBA: Dbac_0184
            DRT: Dret_2487
            DAK: DaAHT2_0039
            DPR: Despr_2152
            DAL: Dalk_3007
            ADE: Adeh_1439
            ACP: A2cp1_2508
            AFW: Anae109_0597 Anae109_3326
            ANK: AnaeK_2421
            MXA: MXAN_0953(zwf)
            SCL: sce4355(zwf1) sce7012(zwf2)
            HOH: Hoch_4431
            DBR: Deba_0223
            MLO: mll6516 mlr4207
            MCI: Mesci_1060 Mesci_2405
            MES: Meso_0159
            SME: SMc03070(zwf)
            SMD: Smed_0300
            RHI: NGR_c03190
            ATU: Atu0600(zwf) Atu4835
            ARA: Arad_0944(zwf) Arad_1403(zwf)
            AVI: Avi_0798(zwf) Avi_7570
            RET: RHE_CH00704(zwf1) RHE_CH01185(zwf2)
            REC: RHECIAT_CH0000785(zwf1) RHECIAT_CH0001273(zwf2)
            RLE: RL0753(zwf) RL1315(zwf) pRL120561
            RLT: Rleg2_0363 Rleg2_0826 Rleg2_4766
            RLG: Rleg_0395 Rleg_0940
            LAS: CLIBASIA_01955
            LSO: CKC_02755
            BME: BMEII0513
            BMI: BMEA_B0756(zwf)
            BMF: BAB2_0460
            BMB: BruAb2_0454(zwf)
            BMC: BAbS19_II04350
            BMS: BRA0778(zwf)
            BMT: BSUIS_B0770(zwf)
            BOV: BOV_A0728(zwf)
            BCS: BCAN_B0790(zwf)
            BMR: BMI_II771(zwf)
            OAN: Oant_3956
            BJA: blr6760(zwf)
            BRA: BRADO5811(zwf)
            BBT: BBta_6317(zwf) BBta_p0094(zwf)
            RPA: RPA3636(zwf)
            RPB: RPB_1890
            RPC: RPC_3672
            RPD: RPD_3476
            RPE: RPE_3710
            RPT: Rpal_4157
            RPX: Rpdx1_1715
            NWI: Nwi_2643
            NHA: Nham_3271
            OCA: OCAR_5068(zwf)
            BHE: BH03910(zwf)
            BQU: BQ02930(zwf)
            BTR: Btr_0599(zwf)
            BGR: Bgr_04210(zwf)
            XAU: Xaut_1017 Xaut_1252
            AZC: AZC_3629
            SNO: Snov_3398 Snov_3856
            MEX: Mext_0545 Mext_1515 Mext_2523
            MEA: Mex_1p0364(zwf) Mex_1p1408(zwf) Mex_1p1864(zwf) Mex_1p2490(zwf)
            MDI: METDI0517(zwf) METDI2177(zwf) METDI3253(zwf)
            MRD: Mrad2831_3905 Mrad2831_4314
            MET: M446_4822 M446_6708
            MPO: Mpop_0516 Mpop_1515 Mpop_2451
            MCH: Mchl_0480 Mchl_1794 Mchl_2746
            MNO: Mnod_1704 Mnod_7447
            BID: Bind_0458 Bind_2867
            MSL: Msil_1125
            RVA: Rvan_3105
            CCR: CC_2057
            CCS: CCNA_02136(zwf)
            CAK: Caul_1438
            CSE: Cseg_1373
            PZU: PHZ_c3256(zwf)
            BSB: Bresu_1037
            AEX: Astex_1954
            SIL: SPO2048(zwf-1) SPO3033(zwf-2)
            SIT: TM1040_0377
            RSP: RSP_2734(zwf)
            RSH: Rsph17029_1392
            RSQ: Rsph17025_1778
            RSK: RSKD131_1057
            RCP: RCAP_rcc02408(zwf)
            JAN: Jann_1969
            RDE: RD1_2722(zwf)
            PDE: Pden_1952
            DSH: Dshi_1684(zwf)
            KVU: EIO_1652
            MMR: Mmar10_2642
            HNE: HNE_1738(zwf)
            HBA: Hbal_1547
            ZMO: ZMO0367
            ZMN: Za10_0873
            NAR: Saro_1893
            SAL: Sala_0190
            SWI: Swit_1623 Swit_2887
            SJP: SJA_C1-20860(zwf)
            ELI: ELI_00545
            GOX: GOX0145
            GBE: GbCGDNIH1_0798 GbCGDNIH1_0853
            ACR: Acry_0465 Acry_1275
            GDI: GDI_0288(zwf) GDI_1408(zwf) GDI_3177(zwf)
            GDJ: Gdia_2111 Gdia_2351 Gdia_3183
            APT: APA01_18870
            AZL: AZL_a09910(zwf)
            APB: SAR116_1986
            BSU: BSU23850(zwf)
            BSS: BSUW23_11785(zwf)
            BAN: BA_3433(zwf)
            BAR: GBAA_3433(zwf)
            BAT: BAS3182
            BAH: BAMEG_1194(zwf)
            BAI: BAA_3467(zwf)
            BAL: BACI_c33350
            BCA: BCE_3412(zwf)
            BCZ: BCZK3083(zwf) BCZK3084(g6pD)
            BCR: BCAH187_A3414(zwf)
            BCB: BCB4264_A3389(zwf)
            BCU: BCAH820_3402(zwf)
            BCG: BCG9842_B1843(zwf)
            BCQ: BCQ_3188
            BCX: BCA_3469(zwf)
            BTK: BT9727_3166(zwf)
            BTL: BALH_3052
            BTB: BMB171_C3064(zwf)
            BWE: BcerKBAB4_3105
            BLI: BL01964(zwf)
            BLD: BLi02555(zwf)
            BAY: RBAM_022160(zwf)
            BAO: BAMF_2285(zwf)
            BAE: BATR1942_10235
            BCL: ABC1924(zwf)
            BPU: BPUM_2116(zwf)
            BMQ: BMQ_1958(zwf) BMQ_3262(zwf) BMQ_5210(zwf)
            BMD: BMD_1913(zwf) BMD_3268(zwf) BMD_5196(zwf)
            BCO: Bcell_1992 Bcell_3667
            OIH: OB2938
            GKA: GK2334
            GTN: GTNG_2264(zwf)
            GWC: GWCH70_2277
            GYM: GYMC10_5505
            GYC: GYMC61_0348
            GYA: GYMC52_2314
            GCT: GC56T3_1169
            GMC: GY4MC1_1226 GY4MC1_3100
            AFL: Aflv_0978(zwf)
            SAU: SA1336
            SAV: SAV1505
            SAW: SAHV_1493
            SAH: SaurJH1_1593 SaurJH1_2809
            SAJ: SaurJH9_1562 SaurJH9_2764
            SAM: MW1459
            SAS: SAS1445
            SAR: SAR1582(zwf)
            SAC: SACOL1549(zwf)
            SAX: USA300HOU_1507
            SAA: SAUSA300_1454(zwf)
            SAO: SAOUHSC_01599
            SAE: NWMN_1412(zwf)
            SAD: SAAV_1495(zwf)
            SAB: SAB1366
            SEP: SE1188
            SER: SERP1067(zwf-2)
            SHA: SH1411
            SSP: SSP1248
            SCA: Sca_1130(zwf)
            SLG: SLGD_01408
            SSD: SPSINT_1200
            LMO: lmo1978
            LMF: LMOf2365_2002(zwf)
            LMH: LMHCC_0583(zwf)
            LMC: Lm4b_01990
            LMN: LM5578_2179
            LMY: LM5923_2130
            LIN: lin2085
            LWE: lwe1997(zwf)
            LSG: lse_1960(zwf)
            MCL: MCCL_1154(zwf)
            BBE: BBR47_37600(zwf)
            PJD: Pjdr2_1111 Pjdr2_2695
            PPY: PPE_02028(zwf1) PPE_03961(zwf2)
            PPM: PPSC2_c2263 PPSC2_c4474
            AAC: Aaci_2551
            LLA: L0044(zwf)
            LLK: LLKF_2489(zwf)
            LLC: LACR_2527
            LLM: llmg_2499
            SPN: SP_1243
            SPD: SPD_1100(zwf)
            SPR: spr1122(zwf)
            SPW: SPCG_1060(zwf)
            SPX: SPG_1133(zwf)
            SNE: SPN23F_11380(zwf)
            SPV: SPH_1358(zwf)
            SNM: SP70585_1305(zwf)
            SJJ: SPJ_1156(zwf)
            SPP: SPP_1280(zwf)
            SNT: SPT_0986(zwf)
            SNC: HMPREF0837_11258(zwf)
            SNB: SP670_1036(zwf)
            SNP: SPAP_1267
            SSA: SSA_1555(gdh)
            SSU: SSU05_1184
            SSV: SSU98_1201
            SSB: SSUBM407_0761(zwf)
            SSI: SSU1025(zwf)
            SSS: SSUSC84_1063(zwf)
            SGO: SGO_0788(zwf)
            SMB: smi_1205(zwf)
            LPL: lp_2681(gpd)
            LPJ: JDM1_2150(gpd)
            LPS: LPST_C2204(gpd)
            LJO: LJ0470
            LJF: FI9785_486(zwf)
            LAC: LBA0413
            LSA: LSA0381(zwf)
            LSL: LSL_0462(zwf)
            LDB: Ldb1611(gpd)
            LBU: LBUL_1490
            LDE: LDBND_1519
            LBR: LVIS_0097
            LCA: LSEI_0778
            LCB: LCABL_08400(zwf)
            LCZ: LCAZH_0721
            LGA: LGAS_0417
            LRE: Lreu_1765
            LRF: LAR_1653
            LHE: lhv_0432
            LFE: LAF_1760
            LRH: LGG_00760(zwf)
            LRL: LC705_00754(zwf)
            LCR: LCRIS_00410(zwf)
            LAM: LA2_02145
            PPE: PEPE_1267
            EFA: EF1004(zwf)
            OOE: OEOE_0135
            LME: LEUM_2016
            LCI: LCK_00052(zwf)
            LKI: LKI_03825
            LGS: LEGAS_0183(zwf)
            CTC: CTC01864
            AMT: Amet_3468
            TTE: TTE1005(zwf)
            TEX: Teth514_1417
            TPD: Teth39_0976
            TIT: Thit_0965
            TMT: Tmath_1020
            TBO: Thebr_1002
            MTA: Moth_2302
            TTM: Tthe_1640
            HOR: Hore_16270
            HAS: Halsa_0822
            ACL: ACL_0962(zwf)
            MTU: Rv1121(zwf1) Rv1447c(zwf2)
            MTC: MT1153(zwf-1) MT1494(zwf-2)
            MRA: MRA_1130(zwf1) MRA_1456(zwf2)
            MTF: TBFG_11144 TBFG_11475
            MTB: TBMG_02534(TBMG_02534.1) TBMG_02861(TBMG_02861.1)
            MBO: Mb1152(zwf1) Mb1482c(zwf2)
            MBB: BCG_1182(zwf1) BCG_1508c(zwf2)
            MBT: JTY_1155(zwf1) JTY_1483(zwf2)
            MPA: MAP1176c(zwf2) MAP1687 MAP2671c(zwf)
            MAV: MAV_1252(zwf) MAV_2733(zwf) MAV_3329(zwf)
            MSM: MSMEG_0314(zwf) MSMEG_3101(zwf)
            MUL: MUL_0149(zwf1) MUL_1842(zwf2)
            MVA: Mvan_2718
            MGI: Mflv_0266 Mflv_3694 Mflv_4263
            MAB: MAB_2761
            MMC: Mmcs_0459 Mmcs_2412 Mmcs_4976
            MKM: Mkms_0470 Mkms_2458 Mkms_5064
            MJL: Mjls_0446 Mjls_2452 Mjls_5357
            MSP: Mspyr1_05100 Mspyr1_30370 Mspyr1_36090
            MMI: MMAR_2252(zwf2) MMAR_4339(zwf1)
            CGL: NCgl1514(cgl1576)
            CGB: cg1778(zwf)
            CGT: cgR_1626
            CEF: CE0542 CE1696
            CDI: DIP1304(zwf)
            CJK: jk0994(zwf)
            CUR: cur_0997
            CAR: cauri_1206(zwf)
            CKP: ckrop_0961(zwf)
            CPU: cpfrc_01103(zwf)
            NFA: nfa35750(zwf)
            RHA: RHA1_ro00555(zwf1) RHA1_ro02369(zwf2) RHA1_ro05641(zwf3)
                 RHA1_ro07184(zwf4) RHA1_ro11166 RHA1_ro11332(zwf5)
            RER: RER_30430(zwf)
            ROP: ROP_20830(zwf) ROP_57040(zwf) ROP_69650(zwf)
            REQ: REQ_22140
            GBR: Gbro_2372
            TPR: Tpau_2524 Tpau_4207
            SRT: Srot_0465
            SCO: SCO1937(SCC22.19) SCO6661(SC5A7.11c)
            SMA: SAV_1768(zwf1) SAV_6313(zwf2)
            SGR: SGR_5586
            SCB: SCAB_15731 SCAB_69901(zwf)
            TWH: TWT343(zwf)
            TWS: TW428(zwf)
            LXX: Lxx11590(zwf)
            CMI: CMM_1074(zwfB) CMM_1519(zwfA1) CMM_1737(zwfA2)
            CMS: CMS_1784(zwf) CMS_1981(zwf)
            ART: Arth_2094 Arth_2490
            AAU: AAur_2094(zwf) AAur_2459(zwf)
            ACH: Achl_1835 Achl_2230 Achl_4518
            AAI: AARI_18900(zwf)
            RSA: RSal33209_1073 RSal33209_2249
            KRH: KRH_00500(zwf) KRH_12160(zwf)
            MLU: Mlut_11400 Mlut_17870
            RMU: RMDY18_10950
            RDN: HMPREF0733_11884(zwf)
            BCV: Bcav_2163
            BFA: Bfae_15250
            JDE: Jden_1262 Jden_1585
            KSE: Ksed_03930 Ksed_13180
            XCE: Xcel_1555
            SKE: Sked_19960
            CFL: Cfla_0081 Cfla_1936
            ICA: Intca_0182 Intca_1691
            PAC: PPA1563
            PAK: HMPREF0675_4630(zwf)
            PFR: PFREUD_15060(zwf)
            NCA: Noca_2538 Noca_4526
            KFL: Kfla_3269 Kfla_5077
            TFU: Tfu_2005
            NDA: Ndas_2976 Ndas_4742
            TCU: Tcur_2210
            SRO: Sros_3374 Sros_6016
            FRA: Francci3_1647
            FRE: Franean1_2073 Franean1_7022
            FRI: FraEuI1c_4865
            FAL: FRAAL4576(zwf)
            ACE: Acel_1124
            NML: Namu_0335 Namu_0725 Namu_2260
            GOB: Gobs_0785 Gobs_2055 Gobs_2934
            KRA: Krad_0133 Krad_1200 Krad_2924
            SEN: SACE_2157(zwf)
            SVI: Svir_15950
            TBI: Tbis_1983
            AMD: AMED_2806(zwf)
            AMI: Amir_5189
            STP: Strop_1668 Strop_3092
            SAQ: Sare_1660 Sare_3319
            MAU: Micau_4330
            MIL: ML5_3973
            CAI: Caci_2244 Caci_2643 Caci_8680
            SNA: Snas_2419 Snas_2996
            BLO: BL0440(zwf2)
            BLJ: BLD_1241(zwf)
            BLN: Blon_0210
            BLL: BLJ_0213
            BLB: BBMN68_1185(zwf)
            BAD: BAD_0631(zwf2)
            BLA: BLA_1010(zwf)
            BLC: Balac_1038
            BLT: Balat_1038
            BDE: BDP_0850(zwf)
            BBI: BBIF_1447(zwf)
            BBP: BBPR_1500(zwf)
            GVA: HMPREF0424_0185(zwf)
            GVG: HMPREF0421_21326(zwf)
            RXY: Rxyl_0051
            CWO: Cwoe_1220 Cwoe_2510 Cwoe_4949
            AFO: Afer_0496 Afer_1521
            CTR: CT185(zwf)
            CTA: CTA_0203(zwf)
            CTB: CTL0437(zwf)
            CTL: CTLon_0432(zwf)
            CTJ: JALI_1791(zwf)
            CTZ: CTB_1791(zwf)
            CMU: TC0457(zwf)
            CPN: CPn0238(zwf)
            CPA: CP0524
            CPJ: CPj0238(zwf)
            CPT: CpB0244
            CCA: CCA00540(zwf)
            CAB: CAB526(zwf)
            CFE: CF0468(zwf)
            PCU: pc0821(zwf)
            WCH: wcw_1132(zwf)
            BBU: BB0636
            BBZ: BbuZS7_0656(zwf)
            BGA: BG0658(zwf)
            BAF: BAPKO_0679(zwf)
            BTU: BT0636
            BHR: BH0636
            BDU: BDU_640(zwf)
            BRE: BRE_643(zwf)
            TPA: TP0478
            TPP: TPASS_0478(zwf)
            SSM: Spirs_1426
            ABA: Acid345_2812
            ACA: ACP_0572(zwf1) ACP_2280(zwf2)
            TSA: AciPR4_0515 AciPR4_1749
            SUS: Acid_5281
            BTH: BT_1221
            BFR: BF1854
            BFS: BF1920(zwf)
            BVU: BVU_2796
            BHL: Bache_2719
            PDI: BDI_0647
            PPN: Palpr_2270
            SRU: SRU_0078(zwf)
            SRM: SRM_00083(zwf)
            RMR: Rmar_2298
            DFE: Dfer_5182
            SLI: Slin_2700
            CPI: Cpin_1481
            PHE: Phep_1675
            FJO: Fjoh_4800
            RBI: RB2501_00241
            ZPR: ZPR_2642
            CAO: Celal_0075
            IPO: Ilyop_2787
            OTE: Oter_3908
            CAA: Caka_2200
            MIN: Minf_0262(zwf) Minf_1496(zwf)
            RBA: RB2735(g6pD)
            PSL: Psta_2488
            PLM: Plim_1200
            IPA: Isop_2384
            SYN: slr1843(zwf)
            SYW: SYNW0750(zwf)
            SYC: syc1768_d(zwf)
            SYF: Synpcc7942_2334
            SYD: Syncc9605_1918
            SYE: Syncc9902_0748
            SYG: sync_1002(zwf)
            SYR: SynRCC307_0759(zwf)
            SYX: SynWH7803_1561(zwf)
            SYP: SYNPCC7002_A1459(zwf)
            CYA: CYA_1699(zwf)
            CYB: CYB_1985(zwf)
            TEL: tll0540(zwf)
            MAR: MAE_43640(zwf)
            CYT: cce_2536(zwf)
            CYP: PCC8801_3806
            CYC: PCC7424_1498
            CYN: Cyan7425_3427
            CYH: Cyan8802_3858
            CYJ: Cyan7822_4173
            CYU: UCYN_11980
            GVI: gvip152(zwf) gvip438(zwf)
            ANA: all4019(zwf)
            NPU: Npun_F2978 Npun_F3304 Npun_F4025
            AVA: Ava_1682 Ava_C0151
            NAZ: Aazo_1091
            PMA: Pro1124(zwf)
            PMM: PMM1074(zwf)
            PMT: PMT1102(zwf)
            PMN: PMN2A_0676
            PMI: PMT9312_1085
            PMB: A9601_11801(zwf)
            PMC: P9515_11641(zwf)
            PMF: P9303_09401(zwf)
            PMG: P9301_11811(zwf)
            PMH: P9215_12101(zwf)
            PMJ: P9211_11141(zwf)
            PME: NATL1_15091(zwf)
            TER: Tery_0684
            AMR: AM1_2877(zwf) AM1_6320(zwf)
            CTE: CT1873(zwf)
            CPC: Cpar_0335
            CCH: Cag_1668
            CPH: Cpha266_2150
            CPB: Cphamn1_2104
            CLI: Clim_2076
            PVI: Cvib_0375
            PLT: Plut_0307
            PPH: Ppha_2483
            PAA: Paes_1906
            RRS: RoseRS_2562
            RCA: Rcas_1852
            CAU: Caur_0501
            CAG: Cagg_3190
            CHL: Chy400_0537
            HAU: Haur_3021
            TRO: trd_1143(zwf)
            STI: Sthe_2436
            ATM: ANT_18590(zwf)
            DRA: DR_1596
            DGE: Dgeo_1974
            DDR: Deide_16460
            DMR: Deima_2379
            TRA: Trad_1970 Trad_2275
            TSC: TSC_c11210(zwf)
            MSV: Mesil_2480 Mesil_3140
            AAE: aq_497(gsdA)
            HYA: HY04AAS1_1282
            HTH: HTH_0379(zwf)
            TAL: Thal_1579
            TMA: TM1155
            TPT: Tpet_1595
            TRQ: TRQ2_1661
            TNA: CTN_1420
            TNP: Tnap_1615
            PMO: Pmob_1133
            DTH: DICTH_1756(zwf)
            DTU: Dtur_0054
            NDE: NIDE0468(zwf1) NIDE2203(zwf2)
            TTR: Tter_0413
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.49
            IUBMB Enzyme Nomenclature: 1.1.1.49
            ExPASy - ENZYME nomenclature database: 1.1.1.49
            BRENDA, the Enzyme Database: 1.1.1.49
            CAS: 9001-40-5
///
ENTRY       EC 1.1.1.50                 Enzyme
NAME        3alpha-hydroxysteroid dehydrogenase (B-specific);
            hydroxyprostaglandin dehydrogenase;
            3alpha-hydroxysteroid oxidoreductase;
            sterognost 3alpha
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)
REACTION    androsterone + NAD(P)+ = 5alpha-androstane-3,17-dione + NAD(P)H + H+
            [RN:R02476 R02477]
ALL_REAC    R02476 R02477;
            (other) R04309 R04310 R04818 R04819 R04824 R04825 R04829 R04830
            R04832 R04833 R04835 R04836 R04837 R04838 R04842 R04843 R04845
            R04846 R08963
SUBSTRATE   androsterone [CPD:C00523];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     5alpha-androstane-3,17-dione [CPD:C00674];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also acts on other 3alpha-hydroxysteroids and on 9-, 11- and
            15-hydroxyprostaglandin. B-specific with respect to NAD+ or NADP+.
REFERENCE   1  [PMID:14406805]
  AUTHORS   JARABAK J, TALALAY P.
  TITLE     Stereospecificity of hydrogen transfer by pyridine nucleotide-linked
            hydroxysteroid dehydrogenases.
  JOURNAL   J. Biol. Chem. 235 (1960) 2147-51.
  ORGANISM  Pseudomonas testosteroni
REFERENCE   2  [PMID:13405910]
  AUTHORS   KOCHAKIAN CD, CARROLL BR, UHRI B.
  TITLE     Comparisons of the oxidation of C19-hydroxysteroids by guinea pig
            liver homogenates.
  JOURNAL   J. Biol. Chem. 224 (1957) 811-8.
  ORGANISM  Cavia porcellus
REFERENCE   3  [PMID:13295221]
  AUTHORS   MARCUS PI, TALALAY P.
  TITLE     Induction and purification of alpha- and beta-hydroxysteroid
            dehydrogenases.
  JOURNAL   J. Biol. Chem. 218 (1956) 661-74.
  ORGANISM  Pseudomonas testosteroni
REFERENCE   4  [PMID:3479982]
  AUTHORS   Penning TM, Sharp RB.
  TITLE     Prostaglandin dehydrogenase activity of purified rat liver 3
            alpha-hydroxysteroid dehydrogenase.
  JOURNAL   Biochem. Biophys. Res. Commun. 148 (1987) 646-52.
  ORGANISM  Rattus norvegicus [GN:rno]
PATHWAY     ec00120  Primary bile acid biosynthesis
            ec00140  Steroid hormone biosynthesis
            ec01100  Metabolic pathways
ORTHOLOGY   K00037  3-alpha-hydroxysteroid dehydrogenase
GENES       HSA: 1109(AKR1C4)
            XFA: XF2269
            XFT: PD1305
            XCC: XCC0353(drb0080)
            XCB: XC_0365
            XCA: xccb100_0379
            XCV: XCV0366
            XAC: XAC0353(drb0080)
            PAP: PSPA7_2450
            PSB: Psyr_2733
            PSP: PSPPH_2428
            PHA: PSHAa2145(hsdA)
            RSO: RS05193(RSp0230)
            REH: H16_B0673
            POL: Bpro_0129
            HSE: Hsero_4583
            MLO: mll7199
            RLE: pRL120488
            SAL: Sala_0895
            MPA: MAP0698
            MAV: MAV_5096
            MSM: MSMEG_4862
            MVA: Mvan_2008 Mvan_4241
            MGI: Mflv_2405 Mflv_4338
            MMC: Mmcs_3782
            MKM: Mkms_3855
            MJL: Mjls_3786
            ART: Arth_1724
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.50
            IUBMB Enzyme Nomenclature: 1.1.1.50
            ExPASy - ENZYME nomenclature database: 1.1.1.50
            BRENDA, the Enzyme Database: 1.1.1.50
            CAS: 9028-56-2
///
ENTRY       EC 1.1.1.51                 Enzyme
NAME        3(or 17)beta-hydroxysteroid dehydrogenase;
            beta-hydroxy steroid dehydrogenase;
            17-ketoreductase;
            17beta-hydroxy steroid dehydrogenase;
            3beta-hydroxysteroid dehydrogenase;
            17beta-hydroxy steroid dehydrogenase;
            3beta-hydroxy steroid dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase
REACTION    testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+
            [RN:R01836 R01838]
ALL_REAC    R01836 R01838;
            (other) R02352 R02353 R03406 R03407
SUBSTRATE   testosterone [CPD:C00535];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     androst-4-ene-3,17-dione [CPD:C00280];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also acts on other 3beta- or 17beta-hydroxysteroids. cf. EC
            1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase.
REFERENCE   1  [PMID:14214322]
  AUTHORS   DAHM K, BREUER H.
  TITLE     [PRECIPITATION OF A 17-BETA-HYDROXYSTEROID:NAD(P) OXIDOREDUCTASE
            FROM THE RAT ADRENAL GLAND.]
  JOURNAL   Hoppe. Seylers. Z. Physiol. Chem. 336 (1964) 63-8.
  ORGANISM  Rattus norvegicus [GN:rno]
REFERENCE   2  [PMID:13549484]
  AUTHORS   LYNN WS Jr, BROWN RH.
  TITLE     The conversion of progesterone to androgens by testes.
  JOURNAL   J. Biol. Chem. 232 (1958) 1015-30.
  ORGANISM  Cavia porcellus
REFERENCE   3  [PMID:13295221]
  AUTHORS   MARCUS PI, TALALAY P.
  TITLE     Induction and purification of alpha- and beta-hydroxysteroid
            dehydrogenases.
  JOURNAL   J. Biol. Chem. 218 (1956) 661-74.
  ORGANISM  Pseudomonas testosteroni
REFERENCE   4  [PMID:193845]
  AUTHORS   Schultz RM, Groman EV, Engel LL.
  TITLE     3(17)beta-Hydroxysteroid dehydrogenase of Pseudomonas testosteroni.
            A convenient purification and demonstration of multiple molecular
            forms.
  JOURNAL   J. Biol. Chem. 252 (1977) 3775-83.
  ORGANISM  Pseudomonas testosteroni
REFERENCE   5  [PMID:13129261]
  AUTHORS   TALALAY P, DOBSON MM.
  TITLE     Purification and properties of a beta-hydroxysteroid dehydrogenase.
  JOURNAL   J. Biol. Chem. 205 (1953) 823-37.
  ORGANISM  Pseudomonas sp.
PATHWAY     ec00140  Steroid hormone biosynthesis
            ec01100  Metabolic pathways
ORTHOLOGY   K05296  3(or 17)beta-hydroxysteroid dehydrogenase
GENES       REH: H16_B0642 H16_B0649
            BUR: Bcep18194_B1514
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.51
            IUBMB Enzyme Nomenclature: 1.1.1.51
            ExPASy - ENZYME nomenclature database: 1.1.1.51
            UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.51
            BRENDA, the Enzyme Database: 1.1.1.51
            CAS: 9015-81-0
///
ENTRY       EC 1.1.1.52                 Enzyme
NAME        3alpha-hydroxycholanate dehydrogenase;
            alpha-hydroxy-cholanate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase
REACTION    3alpha-hydroxy-5beta-cholanate + NAD+ = 3-oxo-5beta-cholanate + NADH
            + H+ [RN:R04139]
ALL_REAC    R04139
SUBSTRATE   3alpha-hydroxy-5beta-cholanate [CPD:C03990];
            NAD+ [CPD:C00003]
PRODUCT     3-oxo-5beta-cholanate [CPD:C03070];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also acts on other 3alpha-hydroxysteroids with an acidic side-chain.
REFERENCE   1  [PMID:14377608]
  AUTHORS   HAYAISHI O, SATO Y, JAKOBY WB, STOHLMAN EF.
  TITLE     Reversible enzymatic oxidation of bile acids.
  JOURNAL   Arch. Biochem. 56 (1955) 554-5.
  ORGANISM  Escherichia freundii
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.52
            IUBMB Enzyme Nomenclature: 1.1.1.52
            ExPASy - ENZYME nomenclature database: 1.1.1.52
            BRENDA, the Enzyme Database: 1.1.1.52
            CAS: 9028-57-3
///
ENTRY       EC 1.1.1.53                 Enzyme
NAME        3alpha(or 20beta)-hydroxysteroid dehydrogenase;
            cortisone reductase;
            (R)-20-hydroxysteroid dehydrogenase;
            dehydrogenase, 20beta-hydroxy steroid;
            Delta4-3-ketosteroid hydrogenase;
            20beta-hydroxysteroid dehydrogenase;
            3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase;
            NADH-20beta-hydroxysteroid dehydrogenase;
            20beta-HSD
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase
REACTION    androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one
            + NADH + H+ [RN:R04330]
ALL_REAC    R04330;
            (other) R04831 R04834 R04844 R04847
SUBSTRATE   androstan-3alpha,17beta-diol [CPD:C03852];
            NAD+ [CPD:C00003]
PRODUCT     17beta-hydroxyandrostan-3-one [CPD:C03917];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     The 3alpha-hydroxy group or 20beta-hydroxy group of pregnane and
            androstane steroids can act as donor.
REFERENCE   1  [PMID:718844]
  AUTHORS   Edwards CA, Orr JC.
  TITLE     Comparison of the 3alpha-and 20beta-hydroxysteroid dehydrogenase
            activities of the cortisone reductase of Streptomyces hydrogenans.
  JOURNAL   Biochemistry. 17 (1978) 4370-6.
  ORGANISM  Streptomyces hydrogenans
REFERENCE   2  [PMID:14403761]
  AUTHORS   HUEBENER HJ, SAHRHOLZ FG
  TITLE     [20 beta-Hydroxysteroid dehydrogenase. 2. Preparation and
            crystallization.]
  JOURNAL   Biochem. Z. 333 (1960) 95-105.
REFERENCE   3  [PMID:14403760]
  AUTHORS   HUEBENER HJ, SAHRHOLZ FG, SCHMIDT-THOME J, NESEMANN G, JUNK R
  TITLE     [20 beta-Hydroxysteroid dehydrogenase, a new crystalline enzyme.]
  JOURNAL   Biochim. Biophys. Acta. 35 (1959) 270-2.
REFERENCE   4  [PMID:13549484]
  AUTHORS   LYNN WS Jr, BROWN RH.
  TITLE     The conversion of progesterone to androgens by testes.
  JOURNAL   J. Biol. Chem. 232 (1958) 1015-30.
  ORGANISM  Rattus norvegicus [GN:rno], Cavia porcellus
REFERENCE   5  [PMID:6936053]
  AUTHORS   Strickler RC, Covey DF, Tobias B.
  TITLE     Study of 3 alpha, 20 beta-hydroxysteroid dehydrogenase with an
            enzyme-generated affinity alkylator: dual enzyme activity at a
            single active site.
  JOURNAL   Biochemistry. 19 (1980) 4950-4.
  ORGANISM  Streptomyces hydrogenans
REFERENCE   6  [PMID:6928375]
  AUTHORS   Sweet F, Samant BR.
  TITLE     Bifunctional enzyme activity at the same active site: study of 3
            alpha and 20 beta activity by affinity alkylation of 3 alpha, 20
            beta-hydroxysteroid dehydrogenase with 17-(bromoacetoxy)steroids.
  JOURNAL   Biochemistry. 19 (1980) 978-86.
  ORGANISM  Streptomyces hydrogenans
PATHWAY     ec00140  Steroid hormone biosynthesis
            ec01100  Metabolic pathways
ORTHOLOGY   K00038  3alpha(or 20beta)-hydroxysteroid dehydrogenase
GENES       PRW: PsycPRwf_0909
            PHA: PSHAa0891
            BUR: Bcep18194_B1012 Bcep18194_B1510
            BCJ: BCAM1582 BCAM1939
            BAC: BamMC406_4593
            GME: Gmet_2226 Gmet_2249
            RLE: RL1197
            BJA: bll0026
            NAR: Saro_3667
            SWI: Swit_3288
            SJP: SJA_C2-05080
            OIH: OB0329
            LBR: LVIS_0330
            MTU: Rv2002(fabG3)
            MTC: MT2058
            MRA: MRA_2018(fabG3-1)
            MTF: TBFG_12034
            MTB: TBMG_01984(TBMG_01984.1)
            MBO: Mb2025(fabG3)
            MBB: BCG_2019(fabG3)
            MBT: JTY_2014(fabG3)
            MPA: MAP1739c MAP3577
            MAV: MAV_2509 MAV_5136
            MSM: MSMEG_2566 MSMEG_3515
            MUL: MUL_1037(fabG3)
            MVA: Mvan_3000
            MGI: Mflv_3281 Mflv_4505
            MAB: MAB_4680c
            MMC: Mmcs_2711
            MKM: Mkms_2755
            MJL: Mjls_2741
            MMI: MMAR_0387(fabG3) MMAR_2981(fabG3_1)
            CGT: cgR_0065
            CKP: ckrop_1446
            NFA: nfa48060
            RHA: RHA1_ro01882
            RER: RER_11770
            ROP: ROP_15600
            GBR: Gbro_2728
            TPR: Tpau_3804
            SCO: SCO4169(SCD66.06)
            SGR: SGR_48t
            SCB: SCAB_52021
            ACH: Achl_1690
            NCA: Noca_2813
            KFL: Kfla_1988 Kfla_2054
            NDA: Ndas_4479
            TCU: Tcur_3357
            SRO: Sros_1990
            FRI: FraEuI1c_2671
            SEN: SACE_4705
            AMD: AMED_2425 AMED_3705
            AMI: Amir_5048
            STP: Strop_2631
            SAQ: Sare_2828
            MAU: Micau_5142
            CAI: Caci_8769
            LBY: Lbys_0205
            MBN: Mboo_0405
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.53
            IUBMB Enzyme Nomenclature: 1.1.1.53
            ExPASy - ENZYME nomenclature database: 1.1.1.53
            BRENDA, the Enzyme Database: 1.1.1.53
            CAS: 9028-42-6
///
ENTRY       EC 1.1.1.54                 Enzyme
NAME        allyl-alcohol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     allyl-alcohol:NADP+ oxidoreductase
REACTION    allyl alcohol + NADP+ = acrolein + NADPH + H+ [RN:R03572]
ALL_REAC    R03572
SUBSTRATE   allyl alcohol [CPD:C02001];
            NADP+ [CPD:C00006]
PRODUCT     acrolein [CPD:C01471];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also acts on saturated primary alcohols.
REFERENCE   1
  AUTHORS   Otsuka, K.
  TITLE     Triphosphopyridine nucleotide-allyl and -ethyl alcohol
            dehydrogenases from Escherichia coli.
  JOURNAL   J. Gen. Appl. Microbiol. 4 (1958) 211-215.
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.54
            IUBMB Enzyme Nomenclature: 1.1.1.54
            ExPASy - ENZYME nomenclature database: 1.1.1.54
            BRENDA, the Enzyme Database: 1.1.1.54
            CAS: 9028-58-4
///
ENTRY       EC 1.1.1.55                 Enzyme
NAME        lactaldehyde reductase (NADPH);
            lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate)
            reductase;
            NADP+-1,2-propanediol dehydrogenase;
            propanediol dehydrogenase;
            1,2-propanediol:NADP+ oxidoreductase;
            lactaldehyde reductase (NADPH)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     propane-1,2-diol:NADP+ oxidoreductase
REACTION    propane-1,2-diol + NADP+ = L-lactaldehyde + NADPH + H+ [RN:R02259]
ALL_REAC    R02259
SUBSTRATE   propane-1,2-diol [CPD:C00583];
            NADP+ [CPD:C00006]
PRODUCT     L-lactaldehyde [CPD:C00424];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     May be identical with EC 1.1.1.2 alcohol dehydrogenase (NADP+).
REFERENCE   1  [PMID:13830319]
  AUTHORS   GUPTA NK, ROBINSON WG.
  TITLE     The enzymatic conversion of lactaldehyde to propanediol.
  JOURNAL   J. Biol. Chem. 235 (1960) 1609-12.
  ORGANISM  Rattus norvegicus [GN:rno], Bos taurus [GN:bta], Sus scofa [GN:ssc],
            Spinacia oleracea, Pseudomonas fluorescens
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.55
            IUBMB Enzyme Nomenclature: 1.1.1.55
            ExPASy - ENZYME nomenclature database: 1.1.1.55
            BRENDA, the Enzyme Database: 1.1.1.55
            CAS: 9028-43-7
///
ENTRY       EC 1.1.1.56                 Enzyme
NAME        ribitol 2-dehydrogenase;
            adonitol dehydrogenase;
            ribitol dehydrogenase A (wild type);
            ribitol dehydrogenase B (mutant enzyme with different properties);
            ribitol dehydrogenase D (mutant enzyme with different properties)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     ribitol:NAD+ 2-oxidoreductase
REACTION    ribitol + NAD+ = D-ribulose + NADH + H+ [RN:R01895]
ALL_REAC    R01895
SUBSTRATE   ribitol [CPD:C00474];
            NAD+ [CPD:C00003]
PRODUCT     D-ribulose [CPD:C00309];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13416220]
  AUTHORS   HOLLMANN S, TOUSTER O.
  TITLE     The L-xylulose-xylitol enzyme and other polyol dehydrogenases of
            guinea pig liver mitochondria.
  JOURNAL   J. Biol. Chem. 225 (1957) 87-102.
  ORGANISM  Cavia porcellus
REFERENCE   2  [PMID:14427582]
  AUTHORS   NORDLIE RC, FROMM HJ.
  TITLE     Ribitol dehydrogenase. II. Studies on the reaction mechanism.
  JOURNAL   J. Biol. Chem. 234 (1959) 2523-31.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
REFERENCE   3  [PMID:13786517]
  AUTHORS   WOOD WA, McDONOUGH MJ, JACOBS LB.
  TITLE     Rihitol and D-arabitol utilization by Aerobacter aerogenes.
  JOURNAL   J. Biol. Chem. 236 (1961) 2190-5.
  ORGANISM  Klebsiella pneumoniae [GN:kpn]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec01100  Metabolic pathways
ORTHOLOGY   K00039  ribitol 2-dehydrogenase
GENES       PIC: PICST_36953(TSC10) PICST_53846(AYR3) PICST_80053(YIM4)
            EOK: G2583_2620
            EFE: EFER_2179
            KPN: KPN_02546
            KPU: KP1_3763
            CKO: CKO_00689
            HEL: HELO_3492(rbtD)
            MMW: Mmwyl1_0908 Mmwyl1_1991
            BXE: Bxe_A0233
            BGL: bglu_2g03610
            HSE: Hsero_1065(rbtD)
            LCH: Lcho_3181
            ATU: Atu4323(rdh)
            ARA: Arad_9649
            AVI: Avi_7375(rdh)
            RET: RHE_PC00223(ypc00125) RHE_PE00178(ype00081) RHE_PF00005(rdh)
            REC: RHECIAT_PA0000135 RHECIAT_PC0000009(rdh)
            RLE: RL0644(rbtD) pRL100461(rbtD) pRL90116
            RLT: Rleg2_4590
            RLG: Rleg_6324
            BME: BMEII0980
            BMI: BMEA_B0269
            BMF: BAB2_0935
            BMB: BruAb2_0912
            BMC: BAbS19_II08640
            BMS: BRA0268
            BMT: BSUIS_B0273
            BOV: BOV_A0243
            BCS: BCAN_B0269(rbtD)
            BMR: BMI_II262(rbtD)
            OAN: Oant_2815
            BJA: bll6662(rdh)
            BRA: BRADO6647(rbtD)
            BBT: BBta_0884(rbtD)
            RSP: RSP_3704
            RSH: Rsph17029_3439
            RSQ: Rsph17025_3589
            RSK: RSKD131_3939
            RCP: RCAP_rcc02370(rbtD)
            PDE: Pden_2157
            DSH: Dshi_0554(rbtD)
            GDI: GDI_2642(rbtD)
            GDJ: Gdia_0856
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.56
            IUBMB Enzyme Nomenclature: 1.1.1.56
            ExPASy - ENZYME nomenclature database: 1.1.1.56
            BRENDA, the Enzyme Database: 1.1.1.56
            CAS: 9014-23-7
///
ENTRY       EC 1.1.1.57                 Enzyme
NAME        fructuronate reductase;
            mannonate oxidoreductase;
            mannonic dehydrogenase;
            D-mannonate dehydrogenase;
            D-mannonate:NAD+ oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-mannonate:NAD+ 5-oxidoreductase
REACTION    D-mannonate + NAD+ = D-fructuronate + NADH + H+ [RN:R02454]
ALL_REAC    R02454
SUBSTRATE   D-mannonate [CPD:C00514];
            NAD+ [CPD:C00003]
PRODUCT     D-fructuronate [CPD:C00905];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also reduces D-tagaturonate.
REFERENCE   1  [PMID:14401695]
  AUTHORS   HICKMAN J, ASHWELL G.
  TITLE     Uronic acid metabolism in bacteria. II. Purification and properties
            of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia
            coli.
  JOURNAL   J. Biol. Chem. 235 (1960) 1566-70.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   2  [PMID:14409051]
  AUTHORS   KILGORE WW, STARR MP.
  TITLE     Catabolism of galacturonic and glucuronic acids by Erwinia
            carotovora.
  JOURNAL   J. Biol. Chem. 234 (1959) 2227-35.
  ORGANISM  Erwinia carotovora [GN:eca]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec01100  Metabolic pathways
ORTHOLOGY   K00040  fructuronate reductase
GENES       ECO: b4323(uxuB)
            ECJ: JW4286(uxuB)
            EBW: BWG_4021(uxuB)
            ECE: Z5921(uxuB)
            ECS: ECs5282
            ECF: ECH74115_5829(uxuB)
            ETW: ECSP_5407(uxuB)
            EOJ: ECO26_5519(uxuB)
            EOI: ECO111_5179(uxuB)
            EOH: ECO103_5104(uxuB)
            ECG: E2348C_4629(uxuB)
            EOK: G2583_5124(uxuB)
            ECC: c5403(uxuB)
            ECP: ECP_4659
            ECI: UTI89_C5019(uxuB)
            ECV: APECO1_2108(uxuB)
            ECX: EcHS_A4549
            ECW: EcE24377A_4921
            ECM: EcSMS35_4850(uxuB)
            ECY: ECSE_4596
            ECR: ECIAI1_4539(uxuB)
            ECQ: ECED1_5205(uxuB)
            ECK: EC55989_4988(uxuB)
            ECT: ECIAI39_4796(uxuB)
            EUM: ECUMN_4931(uxuB)
            ECZ: ECS88_4941(uxuB)
            EBR: ECB_04192(uxuB)
            EBD: ECBD_3712
            EFE: EFER_1533(ydfI) EFER_3029(uxuB)
            STY: STY1553 STY3307(uxuB)
            STT: t3057(uxuB)
            STM: STM1508(ydfI) STM3136
            SPT: SPA1347(ydfI) SPA3004(uxuB)
            SEK: SSPA1252 SSPA2802
            SPQ: SPAB_01802 SPAB_03916
            SEI: SPC_2221(ydfI) SPC_3204(uxuB)
            SEC: SC1525(ydfI) SC3077(uxuB)
            SEH: SeHA_C1678 SeHA_C3382
            SEE: SNSL254_A1619 SNSL254_A3388
            SEW: SeSA_A1610 SeSA_A3318
            SEA: SeAg_B1664 SeAg_B3308
            SED: SeD_A1830 SeD_A3481
            SEG: SG1611(ydfI) SG3030
            SET: SEN1543(ydfI) SEN2979
            SES: SARI_01444 SARI_04490
            YPE: YPO1280
            YPK: y2903
            YPA: YPA_0998
            YPN: YPN_2696
            YPM: YP_1309(mtlD1)
            YPP: YPDSF_2414
            YPG: YpAngola_A1507
            YPZ: YPZ3_1172
            YPS: YPTB1314
            YPI: YpsIP31758_2702
            YPY: YPK_2779
            YPB: YPTS_1406
            YEN: YE1438
            SFL: SF4197(uxuB)
            SFX: S4453(uxuB)
            SFV: SFV_4203(uxuB)
            SSN: SSON_4478(uxuB)
            SBO: SBO_4374(uxuB)
            SBC: SbBS512_E4791(uxuB)
            ECA: ECA0819(uxuB)
            PCT: PC1_0693 PC1_0805
            PWA: Pecwa_0928 Pecwa_1039
            PLU: plu0175(uxuB)
            PAY: PAU_00125(uxuB)
            SGL: SG1837
            ENT: Ent638_1935 Ent638_2768
            ENC: ECL_02178
            ESC: Entcl_1530 Entcl_2316
            ESA: ESA_01067 ESA_01754
            CTU: Ctu_21990(ydfI) Ctu_28380(yeiQ)
            KPN: KPN_01587(ydfI)
            KPE: KPK_1557 KPK_2868
            KPU: KP1_2610(ydfI) KP1_3834(yeiQ)
            KVA: Kvar_1455 Kvar_2770
            CRO: ROD_14851
            SPE: Spro_3239
            EIC: NT01EI_2580
            ETR: ETAE_2291
            DDA: Dd703_0976 Dd703_2638
            DDC: Dd586_0689 Dd586_2942
            DDD: Dda3937_01171(yeiQ) Dda3937_01658(ydfI)
            DZE: Dd1591_1267 Dd1591_3363
            PAM: PANA_3987(ydfI)
            PVA: Pvag_2007(ydfI)
            PAO: Pat9b_2616
            ASU: Asuc_0371
            XCC: XCC4107(mtlD)
            XCB: XC_4198
            XCA: xccb100_4312(uxuB)
            XCV: XCV4338(mtlD)
            XAC: XAC4232(mtlD)
            XOO: XOO4424(mtlD)
            XOM: XOO_4167
            XOP: PXO_03857
            XAL: XALc_0057
            PSU: Psesu_2922
            VVU: VV2_1069
            VVY: VVA1593
            VVM: VVM_03077
            VPA: VPA1705
            PPR: PBPRB1880
            PSP: PSPPH_2593(uxuB)
            CJA: CJA_0180
            PHA: PSHAb0208(uxuB)
            PAT: Patl_0834
            SDE: Sde_0941
            PIN: Ping_0132
            TTU: TERTU_0899
            CSA: Csal_2979
            HEL: HELO_1151(yeiQ)
            MMW: Mmwyl1_2779
            TAU: Tola_2883
            REH: H16_A1937(mtlD)
            CTI: RALTA_A2838
            BMA: BMAA0768
            BMV: BMASAVP1_0581
            BML: BMA10229_0692
            BMN: BMA10247_A1646
            BPS: BPSS1476
            BPM: BURPS1710b_A0508
            BPL: BURPS1106A_A1999
            BPD: BURPS668_A2094
            BAC: BamMC406_5134
            BPY: Bphyt_4721 Bphyt_5747
            BGL: bglu_2g01890
            BPT: Bpet3940
            AXY: AXYL_05545
            POL: Bpro_3970
            VEI: Veis_3560
            VAP: Vapar_2884
            MCI: Mesci_1181
            MES: Meso_4497
            SME: SM_b20749(uxuB)
            SMD: Smed_4245
            RHI: NGR_b20770
            ATU: Atu3530(uxuB)
            ARA: Arad_8887(uxuB)
            AVI: Avi_3896(uxuB)
            RET: RHE_CH00089(uxuB)
            REC: RHECIAT_CH0000093(uxuB)
            RLE: RL0098
            RLT: Rleg2_4022
            RLG: Rleg_4352
            BME: BMEII0478
            BMI: BMEA_B0790
            BMF: BAB2_0426
            BMB: BruAb2_0421
            BMC: BAbS19_II04010
            BOV: BOV_A0761
            BCS: BCAN_B0825(mtlK)
            BMR: BMI_II805
            OAN: Oant_4096
            BJA: blr6836(uxuB)
            BBT: BBta_2118
            AZC: AZC_3347
            SNO: Snov_4292
            MNO: Mnod_0976
            CCS: CCNA_01554
            CAK: Caul_1753
            CSE: Cseg_1548
            PZU: PHZ_c2458(mtlK)
            BSB: Bresu_1684
            AEX: Astex_0453
            SIL: SPO1724(uxuB)
            SIT: TM1040_3866
            RSP: RSP_0480(uxuB)
            RSH: Rsph17029_2132
            RSQ: Rsph17025_2405
            RSK: RSKD131_1813
            RDE: RD1_2933(uxuB)
            KVU: EIO_3034
            HBA: Hbal_2811
            NAR: Saro_3524
            SWI: Swit_1886
            SJP: SJA_C2-03410
            ACR: Acry_1859
            GDI: GDI_0886(mtlK)
            GDJ: Gdia_1133
            APT: APA01_40070
            AZL: AZL_e02210(uxuB)
            APB: SAR116_0903
            PPY: PPE_02411
            PPM: PPSC2_c2587
            LLA: L0241(uxuB)
            LLK: LLKF_1789(uxuB)
            LLC: LACR_1746
            LLM: llmg_0858(uxuB)
            LBR: LVIS_0139
            LRH: LGG_00057(uxuB)
            LRL: LC705_00048(uxuB)
            CBE: Cbei_4083
            CPY: Cphy_1062
            CCE: Ccel_0139
            CSH: Closa_1622
            AMT: Amet_1293
            APR: Apre_1602
            EEL: EUBELI_20594
            BPB: bpr_I0686(uxuB)
            RAL: Rumal_0189
            TTE: TTE1940(mtlD2)
            TIT: Thit_0182 Thit_1742
            TMT: Tmath_0239 Tmath_1722
            MTA: Moth_0429
            CSC: Csac_2688
            ATE: Athe_0855
            COB: COB47_0792
            CHD: Calhy_1830
            COW: Calow_0704
            CKI: Calkr_1857
            CKN: Calkro_1798
            TTM: Tthe_2387
            HAS: Halsa_0906
            MSM: MSMEG_5576
            CGT: cgR_2395
            CEF: CE2378
            RHA: RHA1_ro02788
            ROP: ROP_24050
            ART: Arth_0503
            AAU: AAur_0528
            ACH: Achl_0788 Achl_1006
            RSA: RSal33209_3419
            BCV: Bcav_0601 Bcav_3317
            BFA: Bfae_31040
            JDE: Jden_2406
            XCE: Xcel_2666
            SKE: Sked_05330
            CFL: Cfla_3014
            ICA: Intca_2463
            PAK: HMPREF0675_5408
            KFL: Kfla_2756
            NDA: Ndas_3280
            TCU: Tcur_4796
            FRE: Franean1_3198
            FRI: FraEuI1c_5657
            NML: Namu_4288
            GOB: Gobs_1282
            KRA: Krad_0583
            SEN: SACE_4940 SACE_5054(mtlD)
            SVI: Svir_07170
            AMI: Amir_5059
            MAU: Micau_3550
            MIL: ML5_4846
            AHE: Arch_0440
            BLN: Blon_0668
            BHY: BHWA1_02241(mtlD2)
            BRM: Bmur_2039
            BPO: BP951000_0482(mtlD2)
            PRU: PRU_0735
            PHE: Phep_3764
            RBA: RB2403(uxuB)
            TMA: TM0068
            TPT: Tpet_0856
            TRQ: TRQ2_0879
            TNA: CTN_0625
            TNP: Tnap_0698
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.57
            IUBMB Enzyme Nomenclature: 1.1.1.57
            ExPASy - ENZYME nomenclature database: 1.1.1.57
            BRENDA, the Enzyme Database: 1.1.1.57
            CAS: 9028-44-8
///
ENTRY       EC 1.1.1.58                 Enzyme
NAME        tagaturonate reductase;
            altronic oxidoreductase;
            altronate oxidoreductase;
            TagUAR;
            altronate dehydrogenase;
            D-tagaturonate reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-altronate:NAD+ 3-oxidoreductase
REACTION    D-altronate + NAD+ = D-tagaturonate + NADH + H+ [RN:R02555]
ALL_REAC    R02555
SUBSTRATE   D-altronate [CPD:C00817];
            NAD+ [CPD:C00003]
PRODUCT     D-tagaturonate [CPD:C00558];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:14401695]
  AUTHORS   HICKMAN J, ASHWELL G.
  TITLE     Uronic acid metabolism in bacteria. II. Purification and properties
            of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia
            coli.
  JOURNAL   J. Biol. Chem. 235 (1960) 1566-70.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00040  Pentose and glucuronate interconversions
            ec01100  Metabolic pathways
ORTHOLOGY   K00041  tagaturonate reductase
GENES       ECO: b1521(uxaB)
            ECJ: JW1514(uxaB)
            EBW: BWG_1340(uxaB)
            ECE: Z2184(uxaB)
            ECS: ECs2128
            ECF: ECH74115_2134(uxaB)
            ETW: ECSP_2006(uxaB)
            EOJ: ECO26_2122(uxaB)
            EOI: ECO111_1917(uxaB)
            EOH: ECO103_1651(uxaB)
            ECG: E2348C_1642(uxaB)
            EOK: G2583_1886(uxaB)
            ECP: ECP_1505
            ECI: UTI89_C1740(uxaB)
            ECV: APECO1_641(uxaB)
            ECX: EcHS_A1603(uxaB)
            ECW: EcE24377A_1721(uxaB)
            ECM: EcSMS35_1651(uxaB)
            ECY: ECSE_1611
            ECR: ECIAI1_1533(uxaB)
            ECQ: ECED1_1653(uxaB)
            ECK: EC55989_1654(uxaB)
            ECT: ECIAI39_1785(uxaB)
            EUM: ECUMN_1789(uxaB)
            ECZ: ECS88_1598(uxaB)
            ECL: EcolC_2137
            EBR: ECB_01478(uxaB)
            EBD: ECBD_2121
            EFE: EFER_1553(uxaB)
            YPE: YPO0580(uxaB)
            YPK: y3599(uxaB)
            YPA: YPA_3208 YPA_3209
            YPN: YPN_0449
            YPM: YP_2900(uxaB)
            YPP: YPDSF_0367
            YPZ: YPZ3_0556(uxaB)
            YPS: YPTB3477(uxaB)
            YPI: YpsIP31758_0492(uxaB)
            YPY: YPK_0555
            YPB: YPTS_3662
            YEN: YE3707(uxaB)
            SFL: SF1572(uxaB)
            SFX: S1699(uxaB)
            SFV: SFV_1580(uxaB)
            SSN: SSON_1607(uxaB)
            SBC: SbBS512_E1685
            ECA: ECA0646(uxaB1) ECA4383(uxaB2)
            PCT: PC1_0058 PC1_0530
            PWA: Pecwa_0064 Pecwa_0747
            EBI: EbC_05120(uxaB)
            ENT: Ent638_2013
            ENC: ECL_01984
            ESC: Entcl_2285
            ESA: ESA_01824
            CTU: Ctu_21580(uxaB)
            KPN: KPN_01640(uxaB)
            KPE: KPK_2739(uxaB) KPK_4814
            KPU: KP1_2680(uxaB)
            KVA: Kvar_2694 Kvar_4447
            CKO: CKO_01541
            CRO: ROD_15221(uxaB)
            EIC: NT01EI_0503
            ETR: ETAE_0437(uxaB)
            DDA: Dd703_3384
            DDC: Dd586_0556
            DDD: Dda3937_02740(uxaB)
            DZE: Dd1591_3510
            PAM: PANA_3455(uxaB)
            PVA: Pvag_2726(uxaB)
            PAO: Pat9b_3492
            MSU: MS0529(mtlD)
            ASU: Asuc_0155
            PPR: PBPRB1516
            HEL: HELO_3555
            TAU: Tola_3026
            BCN: Bcen_6468
            BCH: Bcen2424_6703
            BCM: Bcenmc03_6309
            BAM: Bamb_1222
            BAC: BamMC406_1248
            BPH: Bphy_6340
            BPY: Bphyt_5477
            BGL: bglu_2g18530
            BGE: BC1002_6155
            PNA: Pnap_2069
            BBA: Bd3477
            SCL: sce1243
            ATU: Atu2813(uxaB)
            ARA: Arad_8417(uxuB)
            OAN: Oant_3906
            XAU: Xaut_0173
            AZC: AZC_3284
            RSH: Rsph17029_0263
            RSK: RSKD131_3010
            AZL: AZL_c04510(uxaB)
            BSU: BSU12380(uxaB)
            BSS: BSUW23_06305(uxaB)
            BHA: BH0492
            BLI: BL00711(uxaB)
            BLD: BLi03513(uxaB)
            BAY: RBAM_012410(uxaB)
            BAE: BATR1942_03830
            BCL: ABC0443(uxaB) ABC1154
            BPU: BPUM_2985(uxaB)
            GYM: GYMC10_4122
            PJD: Pjdr2_2924
            PPY: PPE_02051
            PPM: PPSC2_c2287
            AAC: Aaci_1577
            LLK: LLKF_1709(uxaB)
            CAC: CA_C0695
            CBE: Cbei_1833 Cbei_1838
            CPY: Cphy_2741
            CSH: Closa_1092
            CCB: Clocel_2251
            AMT: Amet_0555
            EEL: EUBELI_00907
            BPB: bpr_I1275(uxaB)
            RAL: Rumal_2177
            TTM: Tthe_2396
            HAS: Halsa_0910
            XCE: Xcel_2656
            BTH: BT_0825
            BVU: BVU_3075
            PRU: PRU_1646
            DFE: Dfer_2842 Dfer_4128
            SLI: Slin_1056 Slin_1247
            LBY: Lbys_1620
            CPI: Cpin_5504 Cpin_6833
            PHE: Phep_1160
            GFO: GFO_1705(uxaB)
            FJO: Fjoh_4259
            ZPR: ZPR_2953
            FBC: FB2170_03360
            CAO: Celal_2508
            FBA: FIC_01884
            STR: Sterm_0701
            CAA: Caka_0717
            PSL: Psta_0940
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.58
            IUBMB Enzyme Nomenclature: 1.1.1.58
            ExPASy - ENZYME nomenclature database: 1.1.1.58
            BRENDA, the Enzyme Database: 1.1.1.58
            CAS: 9028-45-9
///
ENTRY       EC 1.1.1.59                 Enzyme
NAME        3-hydroxypropionate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3-hydroxypropanoate:NAD+ oxidoreductase
REACTION    3-hydroxypropanoate + NAD+ = 3-oxopropanoate + NADH + H+ [RN:R01608]
ALL_REAC    R01608
SUBSTRATE   3-hydroxypropanoate [CPD:C01013];
            NAD+ [CPD:C00003]
PRODUCT     3-oxopropanoate [CPD:C00222];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13672942]
  AUTHORS   DEN H, ROBINSON WG, COON MJ.
  TITLE     Enzymatic conversion of beta-hydroxypropionate to malonic
            semialdehyde.
  JOURNAL   J. Biol. Chem. 234 (1959) 1666-71.
  ORGANISM  Sus scofa [GN:ssc]
PATHWAY     ec00410  beta-Alanine metabolism
            ec00640  Propanoate metabolism
            ec01100  Metabolic pathways
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.59
            IUBMB Enzyme Nomenclature: 1.1.1.59
            ExPASy - ENZYME nomenclature database: 1.1.1.59
            BRENDA, the Enzyme Database: 1.1.1.59
            CAS: 9028-59-5
///
ENTRY       EC 1.1.1.60                 Enzyme
NAME        2-hydroxy-3-oxopropionate reductase;
            tartronate semialdehyde reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-glycerate:NAD(P)+ oxidoreductase
REACTION    (R)-glycerate + NAD(P)+ = 2-hydroxy-3-oxopropanoate + NAD(P)H + H+
            [RN:R01745 R01747]
ALL_REAC    R01745 R01747
SUBSTRATE   (R)-glycerate [CPD:C00258];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     2-hydroxy-3-oxopropanoate [CPD:C01146];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13900766]
  AUTHORS   GOTTO AM, KORNBERG HL.
  TITLE     The metabolism of C2 compounds in micro-organisms. 7. Preparation
            and properties of crystalline tartronic semialdehyde reductase.
  JOURNAL   Biochem. J. 81 (1961) 273-84.
  ORGANISM  Pseudomonas ovalis
PATHWAY     ec00630  Glyoxylate and dicarboxylate metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K00042  2-hydroxy-3-oxopropionate reductase
GENES       TCR: 505807.180 507017.40
            LMA: LmjF30.0180
            ECO: b0509(glxR) b3125(garR)
            ECJ: JW0497(glxR) JW5526(garR)
            ECD: ECDH10B_0465(glxR) ECDH10B_3298(garR)
            EBW: BWG_0386(glxR) BWG_2831(garR)
            ECE: Z0663(ybbQ) Z4477(garR)
            ECS: ECs0570 ECs4003(garR)
            ECF: ECH74115_0610 ECH74115_4437(garR)
            ETW: ECSP_0584(glxR) ECSP_4096(garR)
            EOJ: ECO26_0542(glxR) ECO26_4228(garR)
            EOI: ECO111_0542(glxR) ECO111_3947(garR)
            EOH: ECO103_0482(glxR) ECO103_3870(garR)
            ECG: E2348C_0443(glxR) E2348C_3411(garR)
            EOK: G2583_0629(glxR) G2583_3847(garR)
            ECC: c0624(ybbQ) c3880(garR)
            ECP: ECP_0570 ECP_3215(garR)
            ECI: UTI89_C0538(ybbQ) UTI89_C3556(garR)
            ECV: APECO1_1505(ybbQ) APECO1_3302(garR)
            ECX: EcHS_A0583 EcHS_A3314(garR)
            ECW: EcE24377A_0546 EcE24377A_3603(garR)
            ECM: EcSMS35_0552 EcSMS35_3420(garR) EcSMS35_4864(gcxR)
            ECY: ECSE_0535 ECSE_3409(garR)
            ECR: ECIAI1_0512(glxR) ECIAI1_3273(garR)
            ECQ: ECED1_0529(glxR) ECED1_3786(garR)
            ECK: EC55989_0524(glxR) EC55989_3543(garR)
            ECT: ECIAI39_3624(garR)
            EUM: ECUMN_0550(glxR) ECUMN_3607(garR)
            ECZ: ECS88_0508(glxR) ECS88_3513(garR)
            ECL: EcolC_0575(garR) EcolC_3113
            EBR: ECB_00459(glxR) ECB_02990(garR)
            EBD: ECBD_0617(garR) ECBD_3148
            EFE: EFER_4367(garR)
            STY: STY0567(garR) STY3430(garR)
            STT: t2341(garR) t3168(garR)
            STM: STM0519(glxR) STM3248(garR)
            SPT: SPA2203 SPA3117(garR)
            SEK: SSPA2047 SSPA2910(garR)
            SPQ: SPAB_03044 SPAB_04054(garR)
            SEI: SPC_0534(garR) SPC_3324(garR)
            SEC: SC0559(glxR) SC3195(garR)
            SEH: SeHA_C0627 SeHA_C3546(garR)
            SEE: SNSL254_A0573 SNSL254_A3510(garR)
            SEW: SeSA_A3441(garR)
            SEA: SeAg_B0566 SeAg_B3438(garR)
            SED: SeD_A0568 SeD_A3607(garR)
            SEG: SG0531(glxR) SG3144(garR)
            SET: SEN0500(glxR) SEN3088(garR)
            SES: SARI_04369(garR)
            YPE: YPO3648
            YPA: YPA_3661
            YPN: YPN_3523
            YPS: YPTB3582
            SFL: SF3162(garR)
            SFX: S3377(garR)
            SFV: SFV_3165(garR)
            SSN: SSON_3280(garR)
            SBO: SBO_2990(garR)
            SBC: SbBS512_E3233(garR)
            SDY: SDY_3319(garR)
            ECA: ECA0489 ECA3573(garR)
            PCT: PC1_3393
            PWA: Pecwa_3553(garR)
            EBI: EbC_35510
            SGL: SG0507
            ENT: Ent638_3567(garR)
            ENC: ECL_04514
            ESC: Entcl_3499
            KPN: KPN_03537(garR)
            KPE: KPK_0573(garR)
            KPU: KP1_1363(glxR) KP1_4839(garR)
            KVA: Kvar_0560
            CKO: CKO_04522(garR)
            CRO: ROD_47541(garR)
            DDA: Dd703_0845(garR)
            DDC: Dd586_3332
            DDD: Dda3937_00191(garR)
            DZE: Dd1591_0811(garR)
            PAM: PANA_3082(garR)
            PVA: Pvag_2465(yhaE)
            MSU: MS0692(garR)
            ASU: Asuc_1858(garR)
            VSP: VS_1248
            PPR: PBPRA2273
            PAE: PA1500
            PAU: PA14_45020(glxR)
            PAP: PSPA7_3831
            PAG: PLES_39121
            PPU: PP_4299(glxR)
            PPF: Pput_1570
            PPG: PputGB1_3864
            PPW: PputW619_2310 PputW619_3624
            PFL: PFL_1699
            PFO: Pfl01_1596
            PEN: PSEEN1670(glxR)
            PMY: Pmen_2771
            PSA: PST_3116(glxR)
            AVN: Avin_43420(garR)
            ACB: A1S_1790
            ABY: ABAYE1786
            ABC: ACICU_01881
            ABN: AB57_2118
            ABB: ABBFA_001671
            SON: SO_2771(garR)
            SDN: Sden_2289
            SFR: Sfri_1503
            SAZ: Sama_1975
            PHA: PSHAa1254
            MAQ: Maqu_3742
            PIN: Ping_2750(garR) Ping_3356
            TGR: Tgr7_2984
            HCH: HCH_00576
            HEL: HELO_1047(mmsB) HELO_1603(glxR)
            ABO: ABO_1232(yhaE)
            TAU: Tola_2580(garR)
            GPB: HDN1F_15570(garR)
            LHK: LHK_02488
            RSO: RSc3283(glxR)
            RPI: Rpic_2693 Rpic_3480 Rpic_4497
            RPF: Rpic12D_3153 Rpic12D_4629
            REU: Reut_A1500 Reut_A2701 Reut_A3293
            REH: H16_A3600
            RME: Rmet_1632 Rmet_3450
            CTI: RALTA_A2478(garR) RALTA_A3054(glxR) RALTA_B0765(glxR)
            BMA: BMAA0577(garR)
            BML: BMA10229_0890(garR)
            BMN: BMA10247_A1857(garR)
            BPS: BPSL1450(glxR)
            BPM: BURPS1710b_2426
            BPL: BURPS1106A_2301 BURPS1106A_A1920(garR)
            BPD: BURPS668_2261
            BPR: GBP346_A2372
            BTE: BTH_I2171 BTH_II0977
            BVI: Bcep1808_1804 Bcep1808_1879
            BUR: Bcep18194_A5180 Bcep18194_A5264
            BCN: Bcen_6125 Bcen_6199
            BCH: Bcen2424_1880 Bcen2424_1953
            BCM: Bcenmc03_1903 Bcenmc03_1977
            BCJ: BCAL1951(glxR) BCAL2026
            BAM: Bamb_1817 Bamb_1940
            BAC: BamMC406_1789 BamMC406_1867
            BMU: Bmul_1316 Bmul_1394
            BMJ: BMULJ_01849(garR) BMULJ_01930(garR)
            BXE: Bxe_A2462 Bxe_B0972 Bxe_C0957
            BPH: Bphy_1286 Bphy_1622 Bphy_6215 Bphy_6528
            BPY: Bphyt_1780 Bphyt_4859
            PNU: Pnuc_0594 Pnuc_0958
            BPA: BPP3639
            BBR: BB2674 BB4074
            BPT: Bpet1646
            BAV: BAV2903(glxR)
            RFR: Rfer_0430 Rfer_3038
            POL: Bpro_0394 Bpro_1712 Bpro_3102 Bpro_4563
            PNA: Pnap_0274 Pnap_1600
            VEI: Veis_1704
            DAC: Daci_2119
            VAP: Vapar_3337 Vapar_3956
            CTT: CtCNB1_0910 CtCNB1_3708
            MPT: Mpe_A0975 Mpe_A2972
            HAR: HEAR0217 HEAR0334(glxR)
            MMS: mma_0270(garR1) mma_0381(garR2)
            LCH: Lcho_1123 Lcho_1133
            TIN: Tint_2353 Tint_2856
            NEU: NE0676
            NET: Neut_1881
            NMU: Nmul_A0172
            EBA: ebA3883(tsaR)
            AZO: azo3362(glxR1) azo3363(glxR2)
            TMZ: Tmz1t_1297 Tmz1t_3294 Tmz1t_3295
            TBD: Tbd_0081
            APP: CAP2UW1_2635
            ANT: Arnit_1026
            GUR: Gura_0588 Gura_2805
            GEM: GM21_0331
            PPD: Ppro_2197
            DVM: DvMF_2927(garR)
            DMA: DMR_35000(garR)
            PUB: SAR11_0778(gnd)
            MLO: mlr0254
            MES: Meso_2516 Meso_4460
            SME: SM_b20679(glxR) SMa0237 SMa0516
            SMD: Smed_2487 Smed_4310 Smed_5561
            ATU: Atu2737 Atu4085(garR)
            ARA: Arad_3557 Arad_9669
            AVI: Avi_5035(garR) Avi_5720
            RET: RHE_PC00146(ypc00079)
            RLE: RL2772 RL3773 RL3800 pRL100393
            RLT: Rleg2_3094 Rleg2_4513
            RLG: Rleg_3351 Rleg_3379
            OAN: Oant_0460 Oant_3760
            BJA: blr3168
            BRA: BRADO6761(garR)
            OCA: OCAR_6560
            XAU: Xaut_2369 Xaut_2433
            AZC: AZC_2610 AZC_3490
            SNO: Snov_2985
            MRD: Mrad2831_1777
            MET: M446_6206
            MNO: Mnod_3089 Mnod_7094 Mnod_8654
            SIL: SPO2560(garR)
            RDE: RD1_0672(garR) RD1_0684(glxR)
            DSH: Dshi_4221
            SWI: Swit_3270
            SJP: SJA_C2-03590(garR)
            GBE: GbCGDNIH1_0961
            ACR: Acry_1159 Acry_1592
            AZL: AZL_a04730(garR) AZL_d01180(garR)
            BCA: BCE_2381(garR) BCE_4109
            BCR: BCAH187_A2454
            BCB: BCB4264_A2319
            BCU: BCAH820_2372
            BCG: BCG9842_B3005
            BLD: BLi02105
            BPU: BPUM_3559(garR)
            BMQ: BMQ_1147
            BMD: BMD_1134
            CPF: CPF_0381(garR)
            CDF: CD2813(garR)
            CDC: CD196_2655(garR)
            CDL: CDR20291_2702(garR)
            CBK: CLL_A1570
            CBT: CLH_1483
            CBE: Cbei_1311
            CLJ: CLJU_c00680 CLJU_c28090
            AMT: Amet_2959(garR)
            DSY: DSY4169(garR)
            DHD: Dhaf_1173(garR)
            EEL: EUBELI_01262
            ELM: ELI_1577
            MSM: MSMEG_5477
            MMC: Mmcs_5347
            MKM: Mkms_5436
            MJL: Mjls_5726
            RHA: RHA1_ro02575 RHA1_ro03224 RHA1_ro04661
            ROP: ROP_23000(glxR)
            SCO: SCO6205(SC2G5.26c)
            SMA: SAV_2025(garR)
            SGR: SGR_1322
            SCB: SCAB_18581
            ART: Arth_2453 Arth_3602 Arth_3690
            AAU: AAur_2423 AAur_3507
            ACH: Achl_3437
            AAI: AARI_32360
            KRH: KRH_00810
            BCV: Bcav_3560
            BFA: Bfae_08160
            KFL: Kfla_2136 Kfla_4631 Kfla_4965
            TFU: Tfu_1265
            NDA: Ndas_0555 Ndas_0722
            ACE: Acel_1045
            NML: Namu_0245
            KRA: Krad_2146
            SEN: SACE_1936 SACE_5376(glxR) SACE_6730
            AMD: AMED_4581(garR) AMED_7266(garR)
            AMI: Amir_1312
            CAI: Caci_4729
            SNA: Snas_2547
            RXY: Rxyl_1714 Rxyl_2852
            SSM: Spirs_0509 Spirs_2563
            ABA: Acid345_1903
            SUS: Acid_3982(garR)
            DFE: Dfer_1409
            SYW: SYNW2331
            SYE: Syncc9902_2145
            AVA: Ava_3206
            CAU: Caur_3345
            CAG: Cagg_0261
            CHL: Chy400_3607
            TRO: trd_A0460
            STI: Sthe_3355
            DGE: Dgeo_2614
            TTR: Tter_1923
            HUT: Huta_0338
            PTO: PTO1147
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.60
            IUBMB Enzyme Nomenclature: 1.1.1.60
            ExPASy - ENZYME nomenclature database: 1.1.1.60
            BRENDA, the Enzyme Database: 1.1.1.60
            CAS: 9028-68-6
///
ENTRY       EC 1.1.1.61                 Enzyme
NAME        4-hydroxybutyrate dehydrogenase;
            gamma-hydroxybutyrate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     4-hydroxybutanoate:NAD+ oxidoreductase
REACTION    4-hydroxybutanoate + NAD+ = succinate semialdehyde + NADH + H+
            [RN:R01644]
ALL_REAC    R01644
SUBSTRATE   4-hydroxybutanoate [CPD:C00989];
            NAD+ [CPD:C00003]
PRODUCT     succinate semialdehyde [CPD:C00232];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:14427301]
  AUTHORS   NIRENBERG MW, JAKOBY WB.
  TITLE     Enzymatic utilization of gamma-hydroxybutyric acid.
  JOURNAL   J. Biol. Chem. 235 (1960) 954-60.
  ORGANISM  Pseudomonas sp.
PATHWAY     ec00650  Butanoate metabolism
ORTHOLOGY   K00043  4-hydroxybutyrate dehydrogenase
GENES       RSO: RSp0986(gbd2)
            REH: H16_A1553(gbd)
            BMA: BMA0905 BMAA0572
            BMV: BMASAVP1_A1435
            BML: BMA10229_0895 BMA10229_A0445
            BMN: BMA10247_0717 BMA10247_A1862
            BPS: BPSL2002 BPSS1420
            BPM: BURPS1710b_1823(gbd1) BURPS1710b_A0444
            BPL: BURPS1106A_1668 BURPS1106A_A1925
            BPD: BURPS668_1646 BURPS668_A2018
            BPA: BPP2084(gbd)
            BBR: BB1480(gbd)
            BME: BMEII1094
            RDE: RD1_2171(gbd)
            HNE: HNE_0174(gbd)
            CPF: CPF_0518
            CPR: CPR_0507
            CDF: CD2338(abfH)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.61
            IUBMB Enzyme Nomenclature: 1.1.1.61
            ExPASy - ENZYME nomenclature database: 1.1.1.61
            BRENDA, the Enzyme Database: 1.1.1.61
            CAS: 9028-60-8
///
ENTRY       EC 1.1.1.62                 Enzyme
NAME        estradiol 17beta-dehydrogenase;
            20alpha-hydroxysteroid dehydrogenase;
            17beta,20alpha-hydroxysteroid dehydrogenase;
            17beta-estradiol dehydrogenase;
            estradiol dehydrogenase;
            estrogen 17-oxidoreductase;
            17beta-HSD
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     estradiol-17beta:NAD(P)+ 17-oxidoreductase
REACTION    estradiol-17beta + NAD(P)+ = estrone + NAD(P)H + H+ [RN:R02352
            R02353]
ALL_REAC    R02352 R02353;
            (other) R04681 R04682 R08945 R08980
SUBSTRATE   estradiol-17beta [CPD:C00951];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     estrone [CPD:C00468];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also acts on (S)-20-hydroxypregn-4-en-3-one and related compounds,
            oxidizing the (S)-20-group. B-specific with respect to NAD(P)+ (cf.
            EC 1.1.1.149 20alpha-hydroxysteroid dehydrogenase).
REFERENCE   1  [PMID:4314937]
  AUTHORS   Kautsky MP, Hagerman DD.
  TITLE     17 Beta-estradiol dehydrogenase of ovine ovaries.
  JOURNAL   J. Biol. Chem. 245 (1970) 1978-84.
  ORGANISM  Ovis aries
REFERENCE   2  [PMID:14413943]
  AUTHORS   LANGER LJ, ALEXANDER JA, ENGEL LL.
  TITLE     Human placental estradiol-17 beta dehydrogenase. II. Kinetics and
            substrate specificities.
  JOURNAL   J. Biol. Chem. 234 (1959) 2609-14.
  ORGANISM  Homo sapiens [GN:hsa]
PATHWAY     ec00140  Steroid hormone biosynthesis
            ec01100  Metabolic pathways
ORTHOLOGY   K00044  estradiol 17beta-dehydrogenase
            K13368  estradiol 17beta-dehydrogenase / testosterone
                    17beta-dehydrogenase
            K13369  estradiol 17beta-dehydrogenase / testosterone
                    17beta-dehydrogenase / retinol dehydrogenase
            K13370  estradiol 17beta-dehydrogenase / testosterone
                    17beta-dehydrogenase /
            K13373  estradiol 17beta-dehydrogenase / 3-keto steroid reductase
GENES       HSA: 3292(HSD17B1) 3294(HSD17B2) 51144(HSD17B12) 51478(HSD17B7)
                 7923(HSD17B8) 8630(HSD17B6)
            PTR: 454269(HSD17B2) 454689(HSD17B1) 466046 741010(HSD17B12)
                 746685(HSD17B8) 747814(HSD17B7)
            PON: 100446761(HSD17B7) 100456547(HSD17B2) 100456666
                 100458219(HSD17B6) 100461538
            MCC: 710392(HSD17B1) 713549(HSD17B6) 714282 718119(HSD17B8) 720399
            MMU: 14979(H2-Ke6) 15485(Hsd17b1) 15486(Hsd17b2) 15490(Hsd17b7)
                 27400(Hsd17b6) 56348(Hsd17b12)
            RNO: 25322(Hsd17b1) 286964(Hsd17b6) 29540(Hsd17b7) 361802(Hsd17b8)
                 79243(Hsd17b2) 84013(Hsd17b12)
            CFA: 475939(HSD17B12) 481118(HSD17B6) 489690(HSD17B2)
                 607570(HSD17B1) 607895(HSD17B8) 609364(HSD17B7)
            AML: 100474694 100475452 100477716 100479742 100484147 100484508
            BTA: 353107(HSD17B1) 505212(HSD17B7) 515710(HSD17B2) 532422(HSD17B8)
                 533086(HSD17B6) 616219(HSD17B12) 789567(HSD17B12)
            SSC: 100147712(HSD17B1) 100154372(HSD17B8) 100155418(HSD17B7)
                 100312973(HSD17B2)
            ECB: 100036556(HSD17B1) 100050075 100052840 100059061 100061414
                 100146214
            MDO: 100011776 100013277 100016071 100025234 100031815
            OAA: 100076931
            GGA: 395641 415807(HSD17B2) 424367(HSD17B7) 770297(HSD17B12)
            TGU: 100222823 100223843 100228039 100231423
            XLA: 379747(hsd17b12-b) 495218(hsd17b12-a) 734717(hsd17b7)
            XTR: 100127828 100489679 100497002 548963(hsd17b7) 549425(hsd17b8)
                 549988(hsd17b12)
            DRE: 100332819 322626(hsd17b12b) 327417(hsd17b12a) 402842(hsd17b1)
                 449537(hsd17b2) 64815(hsd17b8) 768185(hsd17b7)
            BFO: BRAFLDRAFT_106524 BRAFLDRAFT_267231 BRAFLDRAFT_291019
            CIN: 100180521 100184861 445663(17-beta-HSD)
            SPU: 588363
            DPO: Dpse_GA17551
            CBR: CBG18334(Cbr-dhs-11)
            NVE: NEMVE_v1g104066
            TAD: TRIADDRAFT_53215
            PIC: PICST_40664(PXP18)
            TET: TTHERM_00024130 TTHERM_00024140 TTHERM_00024170 TTHERM_00024180
                 TTHERM_00024190 TTHERM_00024200 TTHERM_00418230 TTHERM_00802430
            BUR: Bcep18194_A3871 Bcep18194_A5812 Bcep18194_B0662 Bcep18194_B1144
                 Bcep18194_B1176 Bcep18194_B1177
            RET: RHE_PF00466(ypf00240)
            BRA: BRADO4879
            BBT: BBta_3170
            MSM: MSMEG_3112
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.62
            IUBMB Enzyme Nomenclature: 1.1.1.62
            ExPASy - ENZYME nomenclature database: 1.1.1.62
            BRENDA, the Enzyme Database: 1.1.1.62
            CAS: 9028-61-9
///
ENTRY       EC 1.1.1.63                 Enzyme
NAME        testosterone 17beta-dehydrogenase;
            17-ketoreductase;
            17beta-HSD
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     17beta-hydroxysteroid:NAD+ 17-oxidoreductase
REACTION    testosterone + NAD+ = androst-4-ene-3,17-dione + NADH + H+
            [RN:R01836]
ALL_REAC    R01836
SUBSTRATE   testosterone [CPD:C00535];
            NAD+ [CPD:C00003]
PRODUCT     androst-4-ene-3,17-dione [CPD:C00280];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:13696735]
  AUTHORS   ENDAHL GL, KOCHAKIAN CD, HAMM D.
  TITLE     Separation of a triphosphopyridine nucleotide-specific from a
            diphosphopyridine nucleotide-specific 17 beta-hydroxy-(testosterone)
            dehydrogenase of guinea pig liver.
  JOURNAL   J. Biol. Chem. 235 (1960) 2792-6.
  ORGANISM  Cavia porcellus
REFERENCE   2  [PMID:15436478]
  AUTHORS   SWEAT ML, SAMUELS LT, LUMRY R.
  TITLE     Preparation and characterization of the enzyme which converts
            testosterone to androstenedione.
  JOURNAL   J. Biol. Chem. 185 (1950) 75-84.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   3  [PMID:13781425]
  AUTHORS   VILLEE CA, SPENCER JM.
  TITLE     Some properties of the pyridine nucleotide-specific 17 beta-hydroxy
            steroid dehydrogenases of guinea pig liver.
  JOURNAL   J. Biol. Chem. 235 (1960) 3615-9.
  ORGANISM  Cavia porcellus
PATHWAY     ec00140  Steroid hormone biosynthesis
            ec01100  Metabolic pathways
ORTHOLOGY   K13368  estradiol 17beta-dehydrogenase / testosterone
                    17beta-dehydrogenase
            K13369  estradiol 17beta-dehydrogenase / testosterone
                    17beta-dehydrogenase / retinol dehydrogenase
            K13370  estradiol 17beta-dehydrogenase / testosterone
                    17beta-dehydrogenase /
GENES       HSA: 3294(HSD17B2) 7923(HSD17B8) 8630(HSD17B6)
            PTR: 454269(HSD17B2) 746685(HSD17B8)
            PON: 100456547(HSD17B2) 100458219(HSD17B6) 100461538
            MCC: 713549(HSD17B6) 714282 718119(HSD17B8)
            MMU: 14979(H2-Ke6) 15486(Hsd17b2) 27400(Hsd17b6)
            RNO: 286964(Hsd17b6) 361802(Hsd17b8) 79243(Hsd17b2)
            CFA: 481118(HSD17B6) 489690(HSD17B2) 607895(HSD17B8)
            AML: 100474694 100475452 100484508
            BTA: 515710(HSD17B2) 532422(HSD17B8) 533086(HSD17B6)
            SSC: 100154372(HSD17B8) 100312973(HSD17B2)
            ECB: 100052840 100061414 100146214
            MDO: 100025234 100031815
            OAA: 100076931
            GGA: 415807(HSD17B2)
            TGU: 100228039
            XTR: 100497002 549425(hsd17b8)
            DRE: 64815(hsd17b8)
            BFO: BRAFLDRAFT_291019
            CIN: 100184861
            CBR: CBG18334(Cbr-dhs-11)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.63
            IUBMB Enzyme Nomenclature: 1.1.1.63
            ExPASy - ENZYME nomenclature database: 1.1.1.63
            BRENDA, the Enzyme Database: 1.1.1.63
            CAS: 9028-62-0
///
ENTRY       EC 1.1.1.64                 Enzyme
NAME        testosterone 17beta-dehydrogenase (NADP+);
            17-ketoreductase;
            NADP-dependent testosterone-17beta-oxidoreductase;
            testosterone 17beta-dehydrogenase (NADP)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     17beta-hydroxysteroid:NADP+ 17-oxidoreductase
REACTION    testosterone + NADP+ = androst-4-ene-3,17-dione + NADPH + H+
            [RN:R01838]
ALL_REAC    R01838
SUBSTRATE   testosterone [CPD:C00535];
            NADP+ [CPD:C00006]
PRODUCT     androst-4-ene-3,17-dione [CPD:C00280];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also oxidizes 3-hydroxyhexobarbital to 3-oxohexobarbital.
REFERENCE   1  [PMID:13696735]
  AUTHORS   ENDAHL GL, KOCHAKIAN CD, HAMM D.
  TITLE     Separation of a triphosphopyridine nucleotide-specific from a
            diphosphopyridine nucleotide-specific 17 beta-hydroxy-(testosterone)
            dehydrogenase of guinea pig liver.
  JOURNAL   J. Biol. Chem. 235 (1960) 2792-6.
  ORGANISM  Cavia porcellus
REFERENCE   2  [PMID:15436478]
  AUTHORS   SWEAT ML, SAMUELS LT, LUMRY R.
  TITLE     Preparation and characterization of the enzyme which converts
            testosterone to androstenedione.
  JOURNAL   J. Biol. Chem. 185 (1950) 75-84.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   3  [PMID:13781425]
  AUTHORS   VILLEE CA, SPENCER JM.
  TITLE     Some properties of the pyridine nucleotide-specific 17 beta-hydroxy
            steroid dehydrogenases of guinea pig liver.
  JOURNAL   J. Biol. Chem. 235 (1960) 3615-9.
  ORGANISM  Cavia porcellus
PATHWAY     ec00140  Steroid hormone biosynthesis
            ec01100  Metabolic pathways
ORTHOLOGY   K10207  testosterone 17beta-dehydrogenase (NADP+)
GENES       HSA: 3293(HSD17B3)
            PTR: 742116(HSD17B3)
            PON: 100433175
            MCC: 709843(HSD17B3)
            MMU: 15487(Hsd17b3)
            RNO: 117182(Hsd17b3)
            CFA: 606956(HSD17B3)
            AML: 100468038
            BTA: 616934(HSD17B3)
            SSC: 100513224
            ECB: 100062795
            DRE: 393335(hsd17b3)
            TET: TTHERM_00706280
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.64
            IUBMB Enzyme Nomenclature: 1.1.1.64
            ExPASy - ENZYME nomenclature database: 1.1.1.64
            BRENDA, the Enzyme Database: 1.1.1.64
            CAS: 9028-63-1
///
ENTRY       EC 1.1.1.65                 Enzyme
NAME        pyridoxine 4-dehydrogenase;
            pyridoxin dehydrogenase;
            pyridoxol dehydrogenase;
            pyridoxine dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     pyridoxine:NADP+ 4-oxidoreductase
REACTION    pyridoxine + NADP+ = pyridoxal + NADPH + H+ [RN:R01708]
ALL_REAC    R01708
SUBSTRATE   pyridoxine [CPD:C00314];
            NADP+ [CPD:C00006]
PRODUCT     pyridoxal [CPD:C00250];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also oxidizes pyridoxine phosphate.
REFERENCE   1  [PMID:13715611]
  AUTHORS   HOLZER H, SCHNEIDER S.
  TITLE     [Purification and characterization of a TPN-dependent pyridoxol
            dehydrogenase from brewers yeast.]
  JOURNAL   Biochim. Biophys. Acta. 48 (1961) 71-6.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
PATHWAY     ec00750  Vitamin B6 metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K05275  pyridoxine 4-dehydrogenase
GENES       ZMA: 100272747
            SCE: YPR127W
            AGO: AGOS_AAR033W
            KLA: KLLA0B09658g
            LTH: KLTH0D13750g
            PPA: PAS_chr4_0550
            VPO: Kpol_1039p78
            ZRO: ZYRO0C06468g
            CGR: CAGL0D04752g CAGL0I02046g
            DHA: DEHA2A03036g
            PIC: PICST_59193(PLR1)
            PGU: PGUG_01740
            LEL: LELG_05379
            CAL: CaO19.7306
            CDU: CD36_34520
            YLI: YALI0F02013g
            CLU: CLUG_02968
            NCR: NCU02930 NCU09141
            PAN: PODANSg5701
            MGR: MGG_00381(MG00381.4)
            FGR: FG06869.1
            SSL: SS1G_01199
            BFU: BC1G_03253 BC1G_11605
            ANI: AN9179.2
            AFM: AFUA_1G10270
            NFI: NFIA_015400
            AOR: AO090038000402
            ANG: An08g02180 An16g02360
            AFV: AFLA_069440
            ACT: ACLA_025270
            PCS: Pc16g04830
            CPW: CPC735_071360
            URE: UREG_02949
            PNO: SNOG_06819
            TML: GSTUM_00002653001
            SPO: SPAC9E9.11(plr1)
            CNE: CNA00960
            CNB: CNBA0930
            SCM: SCHCODRAFT_68259 SCHCODRAFT_70603
            TET: TTHERM_00962020 TTHERM_00962050 TTHERM_00962060 TTHERM_00962070
                 TTHERM_00962090 TTHERM_01311290
            BUR: Bcep18194_B1236 Bcep18194_B2855
            RLE: RL3415
            RPC: RPC_0451
            RDE: RD1_3755
            RRU: Rru_A1059 Rru_A2876
            SEN: SACE_3303
            AVA: Ava_0134
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.65
            IUBMB Enzyme Nomenclature: 1.1.1.65
            ExPASy - ENZYME nomenclature database: 1.1.1.65
            UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.65
            BRENDA, the Enzyme Database: 1.1.1.65
            CAS: 9028-64-2
///
ENTRY       EC 1.1.1.66                 Enzyme
NAME        omega-hydroxydecanoate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     10-hydroxydecanoate:NAD+ 10-oxidoreductase
REACTION    10-hydroxydecanoate + NAD+ = 10-oxodecanoate + NADH + H+ [RN:R03886]
ALL_REAC    R03886
SUBSTRATE   10-hydroxydecanoate [CPD:C02774];
            NAD+ [CPD:C00003]
PRODUCT     10-oxodecanoate [CPD:C02217];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Also acts, more slowly, on 9-hydroxynonanoate and
            11-hydroxyundecanoate.
REFERENCE   1  [PMID:14202238]
  AUTHORS   KAMEI S, WAKABAYASHI K, SHIMAZONO N.
  TITLE     STUDIES ON OMEGA-OXIDATION OF FATTY ACIDS IN VITRO. II.
            OMEGA-HYDROXY FATTY ACID: NAD OXIDOREDUCTASE.
  JOURNAL   J. Biochem. 56 (1964) 72-6.
  ORGANISM  Oryctolagus cuniculus
REFERENCE   2  [PMID:13771448]
  AUTHORS   MITZ MA, HEINRIKSON RL.
  TITLE     Omega hydroxy fatty acid dehydrogenase.
  JOURNAL   Biochim. Biophys. Acta. 46 (1961) 45-50.
  ORGANISM  Rattus norvegicus [GN:rno], Equus caballus [GN:ecb], Sus scofa
            [GN:ssc], Ovis aries
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.66
            IUBMB Enzyme Nomenclature: 1.1.1.66
            ExPASy - ENZYME nomenclature database: 1.1.1.66
            BRENDA, the Enzyme Database: 1.1.1.66
            CAS: 9028-65-3
///
ENTRY       EC 1.1.1.67                 Enzyme
NAME        mannitol 2-dehydrogenase;
            D-mannitol dehydrogenase;
            mannitol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-mannitol:NAD+ 2-oxidoreductase
REACTION    D-mannitol + NAD+ = D-fructose + NADH + H+ [RN:R00868]
ALL_REAC    R00868
SUBSTRATE   D-mannitol [CPD:C00392];
            NAD+ [CPD:C00003]
PRODUCT     D-fructose [CPD:C00095];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1
  AUTHORS   Martinez, G., Barker, H.A. and Horecker, B.L.
  TITLE     A specific mannitol dehydrogenase from Lactobacillus brevis.
  JOURNAL   J. Biol. Chem. 238 (1963) 1598-1603.
PATHWAY     ec00051  Fructose and mannose metabolism
ORTHOLOGY   K00045  mannitol 2-dehydrogenase
GENES       SCE: YEL070W(DSF1)
            MGR: MGCH7_ch7g1113(MGG_ch7g1113)
            FGR: FG03311.1
            ANI: AN2815.2
            AFM: AFUA_4G14450
            NFI: NFIA_101920
            AOR: AO090011000230
            ANG: An03g02430
            AFV: AFLA_040380
            ACT: ACLA_078730
            PCS: Pc22g09390
            PNO: SNOG_09898
            PAE: PA2342(mtlD)
            PAU: PA14_34360(mtlD)
            PAP: PSPA7_2921(mtlD)
            PAG: PLES_29611(mtlD)
            PPW: PputW619_2037
            PFL: PFL_3074
            PFS: PFLU2741
            PEN: PSEEN1989(mltD)
            PMY: Pmen_4472
            PSA: PST_2194(uxuB)
            AVN: Avin_27360(mtlD)
            CSA: Csal_0643
            HEL: HELO_2490(mtlD)
            BCM: Bcenmc03_5663
            HOH: Hoch_4543
            MLO: mll4920 mlr4057
            MCI: Mesci_0550
            SME: SMc01501(mtlK)
            SMD: Smed_2353
            RHI: NGR_c24690
            ATU: Atu4451(mtlK)
            ARA: Arad_4011(mtlK)
            AVI: Avi_3572(mtlK)
            RET: RHE_CH03678(mtlK)
            REC: RHECIAT_CH0003952(mtlK)
            RLE: RL4214(mtlK)
            RLT: Rleg2_3446
            RLG: Rleg_3748
            OAN: Oant_3848
            BID: Bind_2459 Bind_3797
            CCR: CC_1487
            BSB: Bresu_2841
            SIT: TM1040_0426
            RSP: RSP_0096(mtlK)
            RSH: Rsph17029_1732
            RSQ: Rsph17025_1685
            RSK: RSKD131_1412
            RCP: RCAP_rcc02027(mtlK)
            JAN: Jann_2907
            RDE: RD1_1481(mtlK)
            PDE: Pden_4177
            DSH: Dshi_0969(mtlK)
            ZMN: Za10_1741
            GOX: GOX0849
            GDJ: Gdia_3090
            APT: APA01_10290
            AZL: AZL_b04790(mtlK)
            APB: SAR116_0965
            MPA: MAP3809c
            MAV: MAV_1052 MAV_4838
            MMI: MMAR_0571
            CGL: NCgl0108(cgl0109)
            CGB: cg0143(mtlD)
            CGT: cgR_0185
            RHA: RHA1_ro02810
            RER: RER_36900
            ROP: ROP_25060
            SRT: Srot_2878
            ACH: Achl_1716
            AAI: AARI_01680(mtlK)
            ICA: Intca_2092
            KFL: Kfla_1360
            SRO: Sros_3496
            NML: Namu_3962
            GOB: Gobs_2791
            KRA: Krad_0300
            CAO: Celal_2591
            DGE: Dgeo_2866
            DDR: Deide_3p02120
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.67
            IUBMB Enzyme Nomenclature: 1.1.1.67
            ExPASy - ENZYME nomenclature database: 1.1.1.67
            BRENDA, the Enzyme Database: 1.1.1.67
            CAS: 9001-65-4
///
ENTRY       EC 1.1.1.68       Obsolete  Enzyme
NAME        Transferred to 1.5.1.20
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
COMMENT     Transferred entry: 5,10-methylenetetrahydrofolate reductase. Now EC
            1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H] (EC 1.1.1.68
            created 1965, deleted 1978 [transferred to EC 1.1.99.15, deleted
            1980])
///
ENTRY       EC 1.1.1.69                 Enzyme
NAME        gluconate 5-dehydrogenase;
            5-keto-D-gluconate 5-reductase;
            5-keto-D-gluconate 5-reductase;
            5-ketogluconate 5-reductase;
            5-ketogluconate reductase;
            5-keto-D-gluconate reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-gluconate:NAD(P)+ 5-oxidoreductase
REACTION    D-gluconate + NAD(P)+ = 5-dehydro-D-gluconate + NAD(P)H + H+
            [RN:R01738 R01740]
ALL_REAC    R01738 R01740
SUBSTRATE   D-gluconate [CPD:C00257];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     5-dehydro-D-gluconate [CPD:C01062];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1
  AUTHORS   Ameyama, M. and Adachi, O.
  TITLE     5-Keto-D-gluconate reductase from Gluconobacter suboxydans.
  JOURNAL   Methods Enzymol. 89 (1982) 198-202.
REFERENCE   2
  AUTHORS   De Ley, J.
  TITLE     5-Ketogluconic acid reductase.
  JOURNAL   Methods Enzymol. 9 (1966) 200-203.
REFERENCE   3  [PMID:13939777]
  AUTHORS   OKAMOTO K.
  TITLE     Enzymatic studies on the formation of 5-ketogluconic acid by
            Acetobacter suboxydans. II. 5-ketogluconate reductase.
  JOURNAL   J. Biochem. 53 (1963) 448-52.
  ORGANISM  Acetobacter suboxydans
ORTHOLOGY   K00046  gluconate 5-dehydrogenase
GENES       ECO: b4266(idnO)
            ECJ: JW4223(idnO)
            ECD: ECDH10B_4459(idnO)
            EBW: BWG_3972(idnO)
            ECC: c0321 c5367(idnO)
            ECP: ECP_4515
            ECI: UTI89_C4873(idnO)
            ECV: APECO1_2128(idnO)
            ECX: EcHS_A4522(idnO)
            ECM: EcSMS35_4747(idnO)
            ECQ: ECED1_5120(idnO)
            ECK: EC55989_4824(idnO)
            ECT: ECIAI39_0671 ECIAI39_4739(idnO)
            EUM: ECUMN_4798(idnO)
            EBR: ECB_04132(idnO)
            EBD: ECBD_3770
            STM: STM4483(idnO)
            SPT: SPA4283(idnO)
            SEK: SSPA3980
            SPQ: SPAB_05640
            SEI: SPC_4615(idnO)
            SEC: SC4339(idnO)
            SEH: SeHA_C4887
            SEE: SNSL254_A4831
            SEW: SeSA_A4738
            SEA: SeAg_B1540 SeAg_B4768
            SED: SeD_A4868
            SEG: SG1502 SG4307(idnO)
            SET: SEN1435 SEN4236(idnO)
            YPE: YPO2539(idnO)
            YPK: y1645
            YPA: YPA_2031
            YPN: YPN_2134
            YPM: YP_2350(idnO)
            YPP: YPDSF_1949
            YPG: YpAngola_A1800(idnO)
            YPZ: YPZ3_2243(idnO)
            YPS: YPTB2571(idnO)
            YPI: YpsIP31758_1470(idnO)
            YPY: YPK_1576
            YPB: YPTS_2666
            YEN: YE1363(idnO)
            SSN: SSON_4451(idnO)
            PCT: PC1_2241
            ETA: ETA_28940(idnO)
            EBI: EbC_22230 EbC_39220(idnO)
            SGL: SG1773
            ESC: Entcl_3681
            KPE: KPK_4703(idnO)
            KVA: Kvar_4344
            CKO: CKO_02793
            SPE: Spro_3288
            DDA: Dd703_0222 Dd703_0946
            PAM: PANA_0593(gno)
            PAO: Pat9b_1828 Pat9b_3477 Pat9b_4922
            HSM: HSM_0702
            MSU: MS0955(fabG)
            ASU: Asuc_1156
            CJA: CJA_0168
            AVN: Avin_46750
            SDE: Sde_0949
            TTU: TERTU_1486
            CSA: Csal_1129
            TAU: Tola_0224
            RSO: RSc1763 RSp0947(idnO)
            RSC: RCFBP_11772
            RSL: RPSI07_1806 RPSI07_mp0631(gno)
            RPI: Rpic_1443
            RPF: Rpic12D_1484
            REU: Reut_A1409 Reut_C6091
            REH: H16_A1531 H16_B0062
            RME: Rmet_1851 Rmet_5878
            CTI: RALTA_A1472 RALTA_B0063
            BTE: BTH_II0349
            BUR: Bcep18194_A3725
            BCN: Bcen_0158
            BCH: Bcen2424_0641
            BCM: Bcenmc03_0608 Bcenmc03_6868
            BCJ: BCAL3386(idnO)
            BXE: Bxe_A2748
            BPY: Bphyt_2216 Bphyt_5033
            BGL: bglu_2g13720
            BGE: BC1002_4271
            BPE: BP0464(idnO)
            BPA: BPP4378(idnO)
            BBR: BB1512 BB4964(idnO)
            BPT: Bpet0033(idnO)
            BAV: BAV3384(idnO)
            AXY: AXYL_00061(idnO1) AXYL_01400 AXYL_01890(idnO2)
            RFR: Rfer_2493
            POL: Bpro_2567 Bpro_3524
            PNA: Pnap_1844
            AAV: Aave_2873
            AJS: Ajs_1695
            DIA: Dtpsy_2008
            VEI: Veis_0770 Veis_2353
            DAC: Daci_0266 Daci_3360
            VAP: Vapar_2919 Vapar_3338 Vapar_5326
            VPE: Varpa_2279 Varpa_3179
            CTT: CtCNB1_2704
            ADN: Alide_1888 Alide_2900
            HSE: Hsero_1093(idnO)
            TIN: Tint_1592
            GME: Gmet_2231
            MLO: mlr3785
            MCI: Mesci_3043
            SME: SM_b20692(idnO1) SM_b20750 SMa0513(idnO1)
            SMD: Smed_4244 Smed_5798
            RHI: NGR_b20840 NGR_b22270(idnO)
            ATU: Atu1407 Atu2417 Atu4086(idnO)
            ARA: Arad_3121(idnO) Arad_8618(idnO) Arad_9671(idnO)
            AVI: Avi_5032(idnO) Avi_9124(idnO)
            RET: RHE_PC00144(idnO)
            RLE: RL2835 pRL100391(gno) pRL110084(gno)
            RLT: Rleg2_2136 Rleg2_4511
            RLG: Rleg_2380 Rleg_6414 Rleg_7084
            OAN: Oant_3756
            BJA: blr5277
            BRA: BRADO6762(idnO)
            BBT: BBta_0777(idnO)
            XAU: Xaut_0468 Xaut_2437
            AZC: AZC_2614
            SNO: Snov_1903 Snov_3389
            MNO: Mnod_5663
            BID: Bind_0620
            CCR: CC_1286
            CCS: CCNA_01345
            CAK: Caul_4004
            CSE: Cseg_2091
            SIL: SPO0595(gno) SPO2417(idnO)
            RSP: RSP_2160(gno) RSP_7371
            RSH: Rsph17029_3622
            RSK: RSKD131_4258 RSKD131_4330
            RDE: RD1_1109(idnO) RD1_3809(gno) RD1_3945
            KVU: EIO_1893
            SWI: Swit_0380 Swit_2306
            SJP: SJA_C1-03840 SJA_C2-05510(idnO)
            GOX: GOX2187
            ACR: Acry_0618 Acry_1591
            GDI: GDI_0691
            GDJ: Gdia_1318
            RRU: Rru_A2747
            AZL: AZL_b00310(idnO) AZL_c04980(fabG)
            APB: SAR116_2139
            BCZ: pE33L466_0134
            BPF: BpOF4_13540
            BMQ: BMQ_2354
            BMD: BMD_2316
            OIH: OB0675
            GKA: GK1029
            GTN: GTNG_0891
            GWC: GWCH70_0926
            GYC: GYMC61_1802
            GYA: GYMC52_0929
            GCT: GC56T3_2543
            GMC: GY4MC1_2868
            LSP: Bsph_3231
            AAC: Aaci_0157
            BTS: Btus_2562
            SPY: SPy_0636(idnO)
            SPZ: M5005_Spy_0524(idnO)
            SPM: spyM18_0699
            SPG: SpyM3_0448
            SPS: SPs1408
            SPH: MGAS10270_Spy0519(idnO)
            SPI: MGAS10750_Spy0543(idnO)
            SPJ: MGAS2096_Spy0536(idnO)
            SPK: MGAS9429_Spy0515(idnO)
            SPF: SpyM51339(idnO)
            SPA: M6_Spy0545
            SPB: M28_Spy0503(idnO)
            SOZ: Spy49_0530
            SPN: SP_0320
            SPD: SPD_0292
            SPR: spr0290(gno)
            SPW: SPCG_0326(gno)
            SPX: SPG_0290
            SNE: SPN23F_02940(idnO)
            SPV: SPH_0431
            SNM: SP70585_0384
            SJJ: SPJ_0315
            SPP: SPP_0355
            SNT: SPT_0369
            SNC: HMPREF0837_10623(gno)
            SNB: SP670_0389
            SNP: SPAP_0352
            SAG: SAG1904
            SAN: gbs1891
            SSU: SSU05_1225
            SSV: SSU98_1240
            SSB: SSUBM407_0725(idnO)
            SSI: SSU1064(idnO)
            SSS: SSUSC84_1097(idnO)
            SEQ: SZO_06640
            SEZ: Sez_1303
            SEU: SEQ_1484
            SUB: SUB1604(idnO)
            SDS: SDEG_0650(idnO)
            EFA: EF0426 EF2263
            CAC: CA_C2607
            CBE: Cbei_3371
            CPY: Cphy_0490 Cphy_2534
            CCE: Ccel_2618
            CSH: Closa_2878
            CCB: Clocel_2262
            AOE: Clos_0849
            SLP: Slip_2087
            EEL: EUBELI_01110
            BPB: bpr_I0930(kduD)
            TMR: Tmar_1328
            NTH: Nther_0725
            MSM: MSMEG_3420
            CPU: cpfrc_00142
            RHA: RHA1_ro03299(gno) RHA1_ro04137
            RER: RER_02970(gno)
            ROP: ROP_28410(gno) ROP_40690(gno)
            TPR: Tpau_1688
            SCO: SCO1681(SCI30A.02)
            SMA: SAV_6627(kduD)
            SGR: SGR_1253
            SCB: SCAB_76391 SCAB_9571
            ART: Arth_2452
            AAU: AAur_2422
            ACH: Achl_0214 Achl_0471
            AAI: AARI_28000(idnO)
            SKE: Sked_31400
            NDA: Ndas_4214
            SRO: Sros_6803
            MCU: HMPREF0573_10632(gno)
            RXY: Rxyl_2333
            SHI: Shel_07750
            OLS: Olsu_0175
            SSM: Spirs_0922
            TSA: AciPR4_1061
            BTH: BT_3232
            BFR: BF0072
            BFS: BF0083(gno)
            BVU: BVU_1106
            BHL: Bache_0766
            PRU: PRU_2301(idnO)
            DFE: Dfer_0299 Dfer_4305
            SLI: Slin_3987
            FJO: Fjoh_4263
            RBI: RB2501_01525
            FBC: FB2170_06215
            FBA: FIC_01891
            FNU: FN1687
            OTE: Oter_1273 Oter_4331
            CAA: Caka_0225 Caka_0519
            RBA: RB6802
            PSL: Psta_2028
            DGE: Dgeo_2403
            DDR: Deide_2p02020
            DMR: Deima_1217
            TRA: Trad_1407
            TTH: TTC0235
            TTJ: TTHB016
            TSC: TSC_c11860
            MRB: Mrub_1322
            MSV: Mesil_0465
            TMA: TM0441
            TNP: Tnap_0223
            MAC: MA0107(gno)
            MRU: mru_0443
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.69
            IUBMB Enzyme Nomenclature: 1.1.1.69
            ExPASy - ENZYME nomenclature database: 1.1.1.69
            BRENDA, the Enzyme Database: 1.1.1.69
            CAS: 9028-70-0
///
ENTRY       EC 1.1.1.70       Obsolete  Enzyme
NAME        Deleted entry
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
COMMENT     Deleted entry: D-glucuronolactone dehydrogenase. Now included with
            EC 1.2.1.3 aldehyde dehydrogenase (NAD+) (EC 1.1.1.70 created 1965,
            deleted 1978)
///
ENTRY       EC 1.1.1.71                 Enzyme
NAME        alcohol dehydrogenase [NAD(P)+];
            retinal reductase;
            aldehyde reductase (NADPH/NADH);
            alcohol dehydrogenase [NAD(P)]
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     alcohol:NAD(P)+ oxidoreductase
REACTION    an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ [RN:R07326 R07328]
ALL_REAC    R07326 > R00623 R00754;
            R07328 > R00625 R00746
SUBSTRATE   alcohol [CPD:C00069];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     aldehyde [CPD:C00071];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Reduces aliphatic aldehydes of carbon chain length from 2 to 14,
            with greatest activity on C4, C6 and C8 aldehydes; also reduces
            retinal to retinol.
REFERENCE   1  [PMID:4300551]
  AUTHORS   Fidge NH, Goodman DS.
  TITLE     The enzymatic reducation of retinal to retinol in rat intestine.
  JOURNAL   J. Biol. Chem. 243 (1968) 4372-9.
  ORGANISM  Rattus norvegicus [GN:rno]
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.71
            IUBMB Enzyme Nomenclature: 1.1.1.71
            ExPASy - ENZYME nomenclature database: 1.1.1.71
            UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.71
            BRENDA, the Enzyme Database: 1.1.1.71
            CAS: 37250-10-5
///
ENTRY       EC 1.1.1.72                 Enzyme
NAME        glycerol dehydrogenase (NADP+);
            glycerol dehydrogenase (NADP+)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     glycerol:NADP+ oxidoreductase
REACTION    glycerol + NADP+ = D-glyceraldehyde + NADPH + H+ [RN:R01041]
ALL_REAC    R01041;
            (other) R01036
SUBSTRATE   glycerol [CPD:C00116];
            NADP+ [CPD:C00006]
PRODUCT     D-glyceraldehyde [CPD:C00577];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:4400494]
  AUTHORS   Kormann AW, Hurst RO, Flynn TG.
  TITLE     Purification and properties of an NADP + -dependent glycerol
            dehydrogenase from rabbit skeletal muscle.
  JOURNAL   Biochim. Biophys. Acta. 258 (1972) 40-55.
  ORGANISM  Oryctolagus cuniculus
REFERENCE   2  [PMID:16742532]
  AUTHORS   Toews CJ.
  TITLE     The kinetics and reaction mechanism of the nicotinamide-adenine
            dinucleotide phosphate-specific glycerol dehydrogenase of rat
            skeletal muscle.
  JOURNAL   Biochem. J. 105 (1967) 1067-1073.
  ORGANISM  Rattus norvegicus [GN:rno]
PATHWAY     ec00561  Glycerolipid metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.72
            IUBMB Enzyme Nomenclature: 1.1.1.72
            ExPASy - ENZYME nomenclature database: 1.1.1.72
            BRENDA, the Enzyme Database: 1.1.1.72
            CAS: 37250-11-6
///
ENTRY       EC 1.1.1.73                 Enzyme
NAME        octanol dehydrogenase;
            1-octanol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     octanol:NAD+ oxidoreductase
REACTION    1-octanol + NAD+ = 1-octanal + NADH + H+ [RN:R02878]
ALL_REAC    R02878
SUBSTRATE   1-octanol [CPD:C00756];
            NAD+ [CPD:C00003]
PRODUCT     1-octanal [CPD:C01545];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Acts, less rapidly, on other long-chain alcohols.
REFERENCE   1  [PMID:4308448]
  AUTHORS   Roche B, Azoulay E.
  TITLE     [Regulation of the alcohol dehydrogenases Saccharomyces cerevisiae]
  JOURNAL   Eur. J. Biochem. 8 (1969) 426-34.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
ORTHOLOGY   K00047  octanol dehydrogenase
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.73
            IUBMB Enzyme Nomenclature: 1.1.1.73
            ExPASy - ENZYME nomenclature database: 1.1.1.73
            BRENDA, the Enzyme Database: 1.1.1.73
            CAS: 9031-31-6
///
ENTRY       EC 1.1.1.74       Obsolete  Enzyme
NAME        Deleted entry
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
COMMENT     Deleted entry: D-aminopropanol dehydrogenase (reaction due to EC
            1.1.1.4 (R,R)-butanediol dehydrogenase) (EC 1.1.1.74 created 1972,
            deleted 1976)
///
ENTRY       EC 1.1.1.75                 Enzyme
NAME        (R)-aminopropanol dehydrogenase;
            L-aminopropanol dehydrogenase;
            1-aminopropan-2-ol-NAD+ dehydrogenase;
            L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase;
            1-aminopropan-2-ol-dehydrogenase;
            DL-1-aminopropan-2-ol: NAD+ dehydrogenase;
            L(+)-1-aminopropan-2-ol-NAD+/NADP+ oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-1-aminopropan-2-ol:NAD+ oxidoreductase
REACTION    (R)-1-aminopropan-2-ol + NAD+ = aminoacetone + NADH + H+ [RN:R03759]
ALL_REAC    R03759
SUBSTRATE   (R)-1-aminopropan-2-ol [CPD:C03194];
            NAD+ [CPD:C00003]
PRODUCT     aminoacetone [CPD:C01888];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COFACTOR    Potassium [CPD:C00238]
COMMENT     Requires K+.
REFERENCE   1  [PMID:4385233]
  AUTHORS   Dekker EE, Swain RR.
  TITLE     Formation of Dg-1-amino-2-propanol by a highly purified enzyme from
            Escherichia coli.
  JOURNAL   Biochim. Biophys. Acta. 158 (1968) 306-7.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   2  [PMID:5329339]
  AUTHORS   Tuner JM.
  TITLE     Microbial metabolism of amino ketones. Aminoacetone formation from
            1-aminopropan-2-ol by a dehydrgenase in Escerichia coli.
  JOURNAL   Biochem. J. 99 (1966) 427-33.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   3  [PMID:5340733]
  AUTHORS   Turner JM.
  TITLE     Microbial metabolism of amino ketones. L-1-aminopropan-2-ol
            dehydrogenase and L-threonine dehydrogenase in Escherichia coli.
  JOURNAL   Biochem. J. 104 (1967) 112-21.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00260  Glycine, serine and threonine metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.75
            IUBMB Enzyme Nomenclature: 1.1.1.75
            ExPASy - ENZYME nomenclature database: 1.1.1.75
            BRENDA, the Enzyme Database: 1.1.1.75
            CAS: 37250-13-8
///
ENTRY       EC 1.1.1.76                 Enzyme
NAME        (S,S)-butanediol dehydrogenase;
            L-butanediol dehydrogenase;
            L-BDH;
            L(+)-2,3-butanediol dehydrogenase (L-acetoin forming);
            (S)-acetoin reductase [(S,S)-butane-2,3-diol forming]
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S,S)-butane-2,3-diol:NAD+ oxidoreductase
REACTION    (2S,3S)-butane-2,3-diol + NAD+ = (S)-acetoin + NADH + H+ [RN:R03707]
ALL_REAC    R03707
SUBSTRATE   (2S,3S)-butane-2,3-diol;
            NAD+ [CPD:C00003]
PRODUCT     (S)-acetoin [CPD:C01769];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     This enzyme catalyses the reversible reduction of (S)-acetoin to
            (S,S)-butane-2,3-diol. It can also catalyse the irreversible
            reduction of diacetyl to (S)-acetoin.
REFERENCE   1  [PMID:13837186]
  AUTHORS   TAYLOR MB, JUNI E.
  TITLE     Stereoisomeric specificities of 2,3-butanediol dehydrogenases.
  JOURNAL   Biochim. Biophys. Acta. 39 (1960) 448-57.
  ORGANISM  Bacillus subtilis [GN:bsu], Klebsiella pneumoniae [GN:kpn],
            Pseudomonas hydrophila
REFERENCE   2  [PMID:2040298]
  AUTHORS   Carballo J, Martin R, Bernardo A, Gonzalez J
  TITLE     Purification, characterization and some properties of
            diacetyl(acetoin) reductase from Enterobacter aerogenes.
  JOURNAL   Eur. J. Biochem. 198 (1991) 327-32.
REFERENCE   3  [PMID:11577733]
  AUTHORS   Takusagawa Y, Otagiri M, Ui S, Ohtsuki T, Mimura A, Ohkuma M, Kudo T
  TITLE     Purification and characterization of L-2,3-butanediol dehydrogenase
            of Brevibacterium saccharolyticum C-1012 expressed in Escherichia
            coli.
  JOURNAL   Biosci. Biotechnol. Biochem. 65 (2001) 1876-8.
PATHWAY     ec00650  Butanoate metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.76
            IUBMB Enzyme Nomenclature: 1.1.1.76
            ExPASy - ENZYME nomenclature database: 1.1.1.76
            BRENDA, the Enzyme Database: 1.1.1.76
///
ENTRY       EC 1.1.1.77                 Enzyme
NAME        lactaldehyde reductase;
            propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase;
            L-lactaldehyde:propanediol oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)[or (S)]-propane-1,2-diol:NAD+ oxidoreductase
REACTION    (R)[or (S)]-propane-1,2-diol + NAD+ = (R)[or (S)]-lactaldehyde +
            NADH + H+ [RN:R02258 R03080]
ALL_REAC    R02258 R03080;
            (other) R01781 R02257
SUBSTRATE   (R)-propane-1,2-diol [CPD:C02912];
            (S)-propane-1,2-diol [CPD:C02917];
            NAD+ [CPD:C00003]
PRODUCT     (R)-lactaldehyde [CPD:C00937];
            (S)-lactaldehyde [CPD:C00424];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:14203169]
  AUTHORS   TING SM, SELLINGER OZ, MILLER ON
  TITLE     THE METABOLISM OF LACTALDEHYDE. VI. THE REDUCTION OF D- AND
            L-LACTALDEHYDE IN RAT LIVER.
  JOURNAL   Biochim. Biophys. Acta. 89 (1964) 217-25.
PATHWAY     ec00620  Pyruvate metabolism
            ec00630  Glyoxylate and dicarboxylate metabolism
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00048  lactaldehyde reductase
GENES       ECO: b2799(fucO)
            ECJ: JW2770(fucO)
            ECD: ECDH10B_2968(fucO)
            EBW: BWG_2537(fucO)
            ECE: Z4116(fucO)
            ECS: ECs3659
            ECF: ECH74115_4063(fucO)
            ETW: ECSP_3751(fucO)
            EOJ: ECO26_3869(fucO)
            EOI: ECO111_3524(fucO)
            EOH: ECO103_3342(fucO)
            ECG: E2348C_3066(fucO)
            EOK: G2583_3452(fucO)
            ECC: c3367(fucO)
            ECP: ECP_2782
            ECI: UTI89_C3170(fucO)
            ECV: APECO1_3732(fucO)
            ECX: EcHS_A2943(fucO)
            ECW: EcE24377A_3104(fucO)
            ECM: EcSMS35_2939(fucO)
            ECY: ECSE_3059
            ECR: ECIAI1_2909(fucO)
            ECQ: ECED1_3252(fucO)
            ECK: EC55989_3078(fucO)
            ECT: ECIAI39_3221(fucO)
            EUM: ECUMN_3128(fucO)
            ECZ: ECS88_3068(fucO)
            ECL: EcolC_0913
            EBR: ECB_02644(fucO)
            EBD: ECBD_0929
            STY: STY3112(fucO)
            STT: t2881(fucO)
            STM: STM2973(fucO)
            SPT: SPA2837(fucO)
            SEK: SSPA2643
            SPQ: SPAB_03699
            SEI: SPC_3030(fucO)
            SEC: SC2912(fucO)
            SEH: SeHA_C3181(fucO)
            SEE: SNSL254_A3196(fucO)
            SEW: SeSA_A3133(fucO)
            SEA: SeAg_B3116(fucO)
            SED: SeD_A3296(fucO)
            SEG: SG2883(fucO)
            SET: SEN2818(fucO)
            SES: SARI_04689
            SFL: SF2813(fucO)
            SFX: S3008(fucO)
            SFV: SFV_2878(fucO)
            SSN: SSON_2956(fucO)
            SDY: SDY_3016(fucO)
            ECA: ECA0742(fucO)
            PCT: PC1_0621
            PWA: Pecwa_0837
            EBI: EbC_38970(fucO)
            ESC: Entcl_3258
            KPN: KPN_03150(fucO)
            KPE: KPK_0969(fucO)
            KPU: KP1_4430(fucO)
            KVA: Kvar_0903
            CKO: CKO_04157
            ETR: ETAE_0294(fucO)
            DDA: Dd703_3316
            DDC: Dd586_0626
            DDD: Dda3937_02309(fucO)
            DZE: Dd1591_3438
            PVA: Pvag_pPag30186(fucO)
            MSU: MS2325(eutG)
            APL: APL_1689
            APJ: APJL_1721(fucO)
            APA: APP7_1750
            CPF: CPF_1046(fucO)
            CPR: CPR_0927
            CBE: Cbei_0455
            CCB: Clocel_1504
            VPR: Vpar_1772
            EEL: EUBELI_20348
            ERE: EUBREC_1091
            ELM: ELI_1743
            BPB: bpr_I2065(fucO)
            MCD: MCRO_0019(fucO)
            BLO: BL1673(fucO)
            BLJ: BLD_1839(dhaT)
            BLN: Blon_0540
            BLL: BLJ_1640
            BLB: BBMN68_1706(dhaT)
            BAD: BAD_0403(fucO)
            BDE: BDP_0538(fucO)
            BBI: BBIF_1397(fucO)
            BBP: BBPR_1454(fucO)
            GVG: HMPREF0421_20697(fucO)
            OLS: Olsu_1397
            BRM: Bmur_2495
            BPO: BP951000_0138(adh)
            BTH: BT_3767
            BFR: BF0254
            BFS: BF0212(fucO)
            BVU: BVU_1251
            BHL: Bache_2994
            LBA: Lebu_1790
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.77
            IUBMB Enzyme Nomenclature: 1.1.1.77
            ExPASy - ENZYME nomenclature database: 1.1.1.77
            BRENDA, the Enzyme Database: 1.1.1.77
            CAS: 37250-15-0
///
ENTRY       EC 1.1.1.78                 Enzyme
NAME        methylglyoxal reductase (NADH-dependent);
            methylglyoxal reductase;
            D-lactaldehyde dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-lactaldehyde:NAD+ oxidoreductase
REACTION    (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+ [RN:R02527]
ALL_REAC    R02527
SUBSTRATE   (R)-lactaldehyde [CPD:C00937];
            NAD+ [CPD:C00003]
PRODUCT     methylglyoxal [CPD:C00546];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     This mammalian enzyme differs from the yeast enzyme, EC 1.1.1.283,
            methylglyoxal reductase (NADPH-dependent), in using NADH rather than
            NADPH as reductant. It oxidizes HO-CH2-CHOH-CHO (glyceraldehyde) as
            well as CH3-CHOH-CHO (lactaldehyde).
REFERENCE   1  [PMID:14323585]
  AUTHORS   TING SM, MILLER ON, SELLINGER OZ.
  TITLE     THE METABOLISM OF LACTALDEHYDE. VII. THE OXIDATION OF D-LACTALDEHYDE
            IN RAT LIVER.
  JOURNAL   Biochim. Biophys. Acta. 97 (1965) 407-15.
  ORGANISM  Rattus norvegicus [GN:rno]
PATHWAY     ec00620  Pyruvate metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.78
            IUBMB Enzyme Nomenclature: 1.1.1.78
            ExPASy - ENZYME nomenclature database: 1.1.1.78
            BRENDA, the Enzyme Database: 1.1.1.78
            CAS: 37250-16-1
///
ENTRY       EC 1.1.1.79                 Enzyme
NAME        glyoxylate reductase (NADP+);
            NADPH-glyoxylate reductase;
            glyoxylate reductase (NADP)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     glycolate:NADP+ oxidoreductase
REACTION    glycolate + NADP+ = glyoxylate + NADPH + H+ [RN:R00465]
ALL_REAC    R00465;
            (other) R01392 R02527
SUBSTRATE   glycolate [CPD:C00160];
            NADP+ [CPD:C00006]
PRODUCT     glyoxylate [CPD:C00048];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also reduces hydroxypyruvate to glycerate; has some affinity for
            NAD+.
REFERENCE   1  [PMID:16742459]
  AUTHORS   Cartwright LN, Hullin RP.
  TITLE     Purification and properties of two glyoxylate reductases from a
            species of Pseudomonas.
  JOURNAL   Biochem. J. 101 (1966) 781-791.
  ORGANISM  Pseudomonas sp.
REFERENCE   2  [PMID:3548703]
  AUTHORS   Kleczkowski LA, Randall DD, Blevins DG.
  TITLE     Purification and characterization of a novel NADPH(NADH)-dependent
            glyoxylate reductase from spinach leaves. Comparison of
            immunological properties of leaf glyoxylate reductase and
            hydroxypyruvate reductase.
  JOURNAL   Biochem. J. 239 (1986) 653-9.
  ORGANISM  Spinacia oleracea
PATHWAY     ec00620  Pyruvate metabolism
            ec00630  Glyoxylate and dicarboxylate metabolism
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00049  glyoxylate reductase (NADP+)
            K12972  gyoxylate/hydroxypyruvate reductase A
GENES       HSA: 9380(GRHPR)
            MMU: 76238(Grhpr)
            DME: Dmel_CG31674
            CME: CMQ289C
            ECO: b1033(ghrA)
            ECJ: JW5146(ycdW)
            ECD: ECDH10B_1105(ycdW)
            EBW: BWG_0882(ghrA)
            ECE: Z1666(ycdW)
            ECS: ECs1410
            ECF: ECH74115_1411
            ETW: ECSP_1334(ycdW)
            EOJ: ECO26_1366(ycdW)
            EOI: ECO111_1310(ycdW)
            EOH: ECO103_1078(ycdW)
            ECG: E2348C_1123(ghrA)
            EOK: G2583_1291(ghrA)
            ECC: c1295(ycdW)
            ECP: ECP_1025
            ECI: UTI89_C1154(ycdW)
            ECV: APECO1_118(ycdW)
            ECX: EcHS_A1151
            ECM: EcSMS35_2100
            ECY: ECSE_1095
            ECR: ECIAI1_1067(ycdW)
            ECQ: ECED1_1177(ycdW)
            ECK: EC55989_1146(ycdW)
            ECT: ECIAI39_2130(ycdW)
            EUM: ECUMN_1207(ycdW)
            ECZ: ECS88_1044(ycdW)
            ECL: EcolC_2566
            EBR: ECB_01030(ycdW)
            EBD: ECBD_2566
            EFE: EFER_1897(ycdW)
            STY: STY1172
            STT: t1785
            STM: STM1135(ycdW)
            SPT: SPA1716(ycdW)
            SEK: SSPA1596
            SPQ: SPAB_02402
            SEI: SPC_2615(ycdW)
            SEC: SC1083(ycdW)
            SEH: SeHA_C1245
            SEE: SNSL254_A1230
            SEW: SeSA_A1200
            SEA: SeAg_B2056
            SED: SeD_A2239
            SEG: SG1987(ycdW)
            SET: SEN1913(ycdW)
            SES: SARI_01863
            YEN: YE2422
            SSN: SSON_1042(ycdW)
            SBO: SBO_2035(ycdW)
            SBC: SbBS512_E2296
            SDY: SDY_1004(ycdW)
            ETA: ETA_14400(ycdW)
            EPY: EpC_14640
            EBI: EbC_26190 EbC_28150 EbC_28270
            PLU: plu2086
            PAY: PAU_02507(ycdW)
            ENT: Ent638_1549
            ENC: ECL_02607
            ESC: Entcl_2748
            ESA: ESA_02341
            CTU: Ctu_16120(ghrA)
            KPN: KPN_01056(ycdW) KPN_02979
            KPE: KPK_1152 KPK_3501
            KPU: KP1_2043(ycdW) KP1_4239
            KVA: Kvar_1089 Kvar_3325
            CKO: CKO_02036
            CRO: ROD_10911
            SPE: Spro_1933
            PMR: PMI1094
            EIC: NT01EI_1576
            ETR: ETAE_1416
            DDD: Dda3937_03024(ycdW)
            XBO: XBJ1_2213(ghrA)
            XNE: XNC1_2134(ghrA)
            PAM: PANA_1555(ycdW) PANA_2406(ycdW)
            PVA: Pvag_1013(ycdW) Pvag_1879
            PAO: Pat9b_1558 Pat9b_2478
            PST: PSPTO_0258
            PSB: Psyr_0147
            PSP: PSPPH_5039
            PFO: Pfl01_3899
            PFS: PFLU4037
            PSA: PST_1590
            PHA: PSHAa2153
            PAT: Patl_1447
            PSM: PSM_A0980
            PIN: Ping_2133
            HCH: HCH_06811
            CSA: Csal_2734
            HEL: HELO_3667
            MMW: Mmwyl1_3064 Mmwyl1_3293
            TAU: Tola_0642
            CVI: CV_1724
            RSO: RSc0262
            RSC: RCFBP_21231
            RSL: RPSI07_3152 RPSI07_mp1041
            RPI: Rpic_0115
            RPF: Rpic12D_0122
            REU: Reut_A0152
            REH: H16_A0185 H16_B0466(serA3)
            RME: Rmet_0118
            CTI: RALTA_A0128 RALTA_B0703
            BPS: BPSL0334
            BPM: BURPS1710b_0544
            BPL: BURPS1106A_0368(ghrA)
            BPD: BURPS668_0354(ghrA)
            BPR: GBP346_A0273
            BTE: BTH_I0314
            BVI: Bcep1808_3047 Bcep1808_6428
            BUR: Bcep18194_A6308
            BCN: Bcen_2344 Bcen_6449
            BCH: Bcen2424_2958 Bcen2424_6684
            BCM: Bcenmc03_2979 Bcenmc03_6281
            BCJ: BCAL0632 BCAS0384
            BAM: Bamb_3006 Bamb_4327 Bamb_6349
            BAC: BamMC406_2869 BamMC406_6053
            BMU: Bmul_2954
            BMJ: BMULJ_00280(serA)
            BXE: Bxe_A4269 Bxe_B1490
            BPH: Bphy_0166 Bphy_3184 Bphy_6567
            BPY: Bphyt_0441 Bphyt_6094
            BGL: bglu_1g32580 bglu_2g10310
            BGE: BC1002_0185 BC1002_4545
            BPE: BP2304
            BPA: BPP2425
            BBR: BB1874
            BPT: Bpet3096(ycdW1) Bpet4875(ycdW2)
            BAV: BAV2205
            AXY: AXYL_00754 AXYL_01281
            RFR: Rfer_3829
            POL: Bpro_0053 Bpro_0422 Bpro_4156
            PNA: Pnap_0476
            AAV: Aave_2182 Aave_3758 Aave_4350
            AJS: Ajs_3758
            DIA: Dtpsy_3039
            VEI: Veis_0512
            DAC: Daci_1407 Daci_5635 Daci_5969
            VAP: Vapar_4717 Vapar_5231 Vapar_5630
            VPE: Varpa_0606 Varpa_5352
            CTT: CtCNB1_0508 CtCNB1_3749
            ADN: Alide_3796
            MPT: Mpe_A0213
            HSE: Hsero_1127(serA) Hsero_2486(serA)
            LCH: Lcho_4179
            TIN: Tint_2718
            HOH: Hoch_3783
            MLO: mll5489 mll7048
            MCI: Mesci_0071
            MES: Meso_4079
            SME: SMa1838
            SMD: Smed_3362 Smed_5604
            RHI: NGR_b06370 NGR_c34780
            ATU: Atu3399 Atu4048 Atu5222
            ARA: Arad_0308 Arad_7092 Arad_7363 Arad_9166
            AVI: Avi_0248 Avi_5861
            RET: RHE_PF00336(ypf00169)
            REC: RHECIAT_CH0000223 RHECIAT_PC0000540
            RLE: pRL120632
            RLT: Rleg2_4136 Rleg2_4424
            RLG: Rleg_4450 Rleg_5028
            BME: BMEI1939
            BMI: BMEA_A0005
            BMF: BAB1_0005
            BMB: BruAb1_0005
            BMC: BAbS19_I00050
            BMS: BR0005
            BMT: BSUIS_A0005
            BOV: BOV_0005
            BCS: BCAN_A0005
            BMR: BMI_I5
            OAN: Oant_0010 Oant_4836
            BJA: bll6710
            BRA: BRADO1153 BRADO3422
            BBT: BBta_1916 BBta_4284
            RPB: RPB_1647
            XAU: Xaut_2571
            AZC: AZC_2038 AZC_3359 AZC_3465
            SNO: Snov_4156
            MRD: Mrad2831_3212 Mrad2831_3223 Mrad2831_5498
            MET: M446_0667 M446_3560
            MNO: Mnod_1511 Mnod_2906
            PZU: PHZ_c2003
            AEX: Astex_2551
            SIL: SPO0415
            SIT: TM1040_0466
            RSP: RSP_3442
            RSH: Rsph17029_3087
            RSQ: Rsph17025_2055
            RSK: RSKD131_3608
            RCP: RCAP_rcc00798
            JAN: Jann_3650
            RDE: RD1_1204
            PDE: Pden_4037 Pden_4963
            DSH: Dshi_0590
            ZMO: ZMO1883
            ZMN: Za10_1258
            NAR: Saro_2948
            GOX: GOX1300
            GDJ: Gdia_1589 Gdia_2170
            RRU: Rru_A2002
            RCE: RC1_3398
            AZL: AZL_026040 AZL_c03180
            APB: SAR116_1484
            GFO: GFO_0312
            RBI: RB2501_14994
            ZPR: ZPR_3640
            FBC: FB2170_11281
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.79
            IUBMB Enzyme Nomenclature: 1.1.1.79
            ExPASy - ENZYME nomenclature database: 1.1.1.79
            BRENDA, the Enzyme Database: 1.1.1.79
            CAS: 37250-17-2
///
ENTRY       EC 1.1.1.80                 Enzyme
NAME        isopropanol dehydrogenase (NADP+);
            isopropanol dehydrogenase (NADP+)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     propan-2-ol:NADP+ oxidoreductase
REACTION    propan-2-ol + NADP+ = acetone + NADPH + H+ [RN:R01550]
ALL_REAC    R01550
SUBSTRATE   propan-2-ol [CPD:C01845];
            NADP+ [CPD:C00006]
PRODUCT     acetone [CPD:C00207];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also acts on other short-chain secondary alcohols and, slowly, on
            primary alcohols.
REFERENCE   1
  AUTHORS   Hoshino, K.
  TITLE     Organism producing isopropanol from acetone. V. Enzymological
            [studies] on the oxidation-reduction of Lactobacillus brevis var.
            hofuensis. [in Japanese].
  JOURNAL   Nippon Nogei Kagaku Kaishi 34 (1960) 608-615.
REFERENCE   2
  AUTHORS   Hoshino, K. and Udagawa, K.
  TITLE     Organism producing isopropanol from acetone. VI. Isopropanol
            dehydrogenase and alcohol dehydrogenase of Lactobacillus brevis var.
            hofuensis. [in Japanese].
  JOURNAL   Nippon Nogei Kagaku Kaishi 34 (1960) 616-619.
PATHWAY     ec00640  Propanoate metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.80
            IUBMB Enzyme Nomenclature: 1.1.1.80
            ExPASy - ENZYME nomenclature database: 1.1.1.80
            BRENDA, the Enzyme Database: 1.1.1.80
            CAS: 37250-18-3
///
ENTRY       EC 1.1.1.81                 Enzyme
NAME        hydroxypyruvate reductase;
            beta-hydroxypyruvate reductase;
            NADH:hydroxypyruvate reductase;
            D-glycerate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-glycerate:NADP+ 2-oxidoreductase
REACTION    D-glycerate + NAD(P)+ = hydroxypyruvate + NAD(P)H + H+ [RN:R01388
            R01392]
ALL_REAC    R01388 R01392
SUBSTRATE   D-glycerate [CPD:C00258];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     hydroxypyruvate [CPD:C00168];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:16667010]
  AUTHORS   Kleczkowski LA, Edwards GE.
  TITLE     Identification of Hydroxypyruvate and Glyoxylate Reductases in Maize
            Leaves.
  JOURNAL   Plant. Physiol. 91 (1989) 278-286.
  ORGANISM  Zea mays [GN:zma]
REFERENCE   2  [PMID:3281657]
  AUTHORS   Kleczkowski LA, Randall DD.
  TITLE     Purification and characterization of a novel NADPH(NADH)-dependent
            hydroxypyruvate reductase from spinach leaves. Comparison of
            immunological properties of leaf hydroxypyruvate reductases.
  JOURNAL   Biochem. J. 250 (1988) 145-52.
  ORGANISM  Spinacia oleracea
REFERENCE   3  [PMID:4385077]
  AUTHORS   Kohn LD, Jakoby WB.
  TITLE     Tartaric acid metabolism. VII. Crystalline hydroxypyruvate reductase
            (D-glycerate dehydrogenase).
  JOURNAL   J. Biol. Chem. 243 (1968) 2494-9.
  ORGANISM  Pseudomonas acidovorans
PATHWAY     ec00260  Glycine, serine and threonine metabolism
            ec00630  Glyoxylate and dicarboxylate metabolism
            ec01100  Metabolic pathways
ORTHOLOGY   K00050  hydroxypyruvate reductase
            K12972  gyoxylate/hydroxypyruvate reductase A
GENES       ECO: b1033(ghrA)
            ECJ: JW5146(ycdW)
            ECD: ECDH10B_1105(ycdW)
            EBW: BWG_0882(ghrA)
            ECE: Z1666(ycdW)
            ECS: ECs1410
            ECF: ECH74115_1411
            ETW: ECSP_1334(ycdW)
            EOJ: ECO26_1366(ycdW)
            EOI: ECO111_1310(ycdW)
            EOH: ECO103_1078(ycdW)
            ECG: E2348C_1123(ghrA)
            EOK: G2583_1291(ghrA)
            ECC: c1295(ycdW)
            ECP: ECP_1025
            ECI: UTI89_C1154(ycdW)
            ECV: APECO1_118(ycdW)
            ECX: EcHS_A1151
            ECM: EcSMS35_2100
            ECY: ECSE_1095
            ECR: ECIAI1_1067(ycdW)
            ECQ: ECED1_1177(ycdW)
            ECK: EC55989_1146(ycdW)
            ECT: ECIAI39_2130(ycdW)
            EUM: ECUMN_1207(ycdW)
            ECZ: ECS88_1044(ycdW)
            ECL: EcolC_2566
            EBR: ECB_01030(ycdW)
            EBD: ECBD_2566
            EFE: EFER_1897(ycdW)
            STY: STY1172
            STT: t1785
            STM: STM1135(ycdW)
            SPT: SPA1716(ycdW)
            SEK: SSPA1596
            SPQ: SPAB_02402
            SEI: SPC_2615(ycdW)
            SEC: SC1083(ycdW)
            SEH: SeHA_C1245
            SEE: SNSL254_A1230
            SEW: SeSA_A1200
            SEA: SeAg_B2056
            SED: SeD_A2239
            SEG: SG1987(ycdW)
            SET: SEN1913(ycdW)
            SES: SARI_01863
            YPE: YPO2536
            YPK: y1651
            YPA: YPA_2028
            YPN: YPN_2131
            YPM: YP_2347(ldhA2)
            YPP: YPDSF_1946
            YPG: YpAngola_A1794
            YPZ: YPZ3_2240
            YPS: YPTB2568
            YPI: YpsIP31758_1475
            YPY: YPK_1579
            YPB: YPTS_2663
            YEN: YE1365 YE2422
            SSN: SSON_1042(ycdW)
            SBO: SBO_2035(ycdW)
            SBC: SbBS512_E2296
            SDY: SDY_1004(ycdW)
            ETA: ETA_14400(ycdW)
            EPY: EpC_14640
            EBI: EbC_26190 EbC_28150 EbC_28270 EbC_39240 EbC_44850(ttuD)
            PLU: plu2086
            PAY: PAU_02507(ycdW)
            ENT: Ent638_1549
            ENC: ECL_02607
            ESC: Entcl_2748 Entcl_3679
            ESA: ESA_02341
            CTU: Ctu_16120(ghrA)
            KPN: KPN_01056(ycdW) KPN_02979
            KPE: KPK_1152 KPK_3184(ttuD) KPK_3501 KPK_4701
            KPU: KP1_2043(ycdW) KP1_2293 KP1_4239
            KVA: Kvar_1089 Kvar_3058 Kvar_3325 Kvar_4342
            CKO: CKO_02036
            CRO: ROD_10911 ROD_11921
            SPE: Spro_1933 Spro_2497
            PMR: PMI1094
            EIC: NT01EI_1576
            ETR: ETAE_1416
            DDD: Dda3937_03024(ycdW)
            XBO: XBJ1_2213(ghrA)
            XNE: XNC1_2134(ghrA)
            PAM: PANA_1555(ycdW) PANA_2406(ycdW)
            PVA: Pvag_1013(ycdW) Pvag_1879 Pvag_pPag30034(hfr)
            PAO: Pat9b_1558 Pat9b_2478 Pat9b_4595 Pat9b_5268
            PPR: PBPRA2272
            PAE: PA1499
            PAU: PA14_45030(ttuD)
            PAP: PSPA7_3833
            PAG: PLES_39131
            PPU: PP_4300
            PPF: Pput_1569
            PPG: PputGB1_3865
            PPW: PputW619_2309 PputW619_3625
            PST: PSPTO_0258
            PSB: Psyr_0147
            PSP: PSPPH_5039
            PFL: PFL_1698
            PFO: Pfl01_1595 Pfl01_3899
            PFS: PFLU1800 PFLU4037
            PEN: PSEEN1669
            PMY: Pmen_2772
            PSA: PST_1590 PST_3117
            PHA: PSHAa2153
            PAT: Patl_0336 Patl_1447
            PSM: PSM_A0980
            AMC: MADE_03376
            PIN: Ping_2133
            ALV: Alvin_0475
            AEH: Mlg_1319
            HHA: Hhal_1267
            TGR: Tgr7_0931
            HCH: HCH_06811
            CSA: Csal_2734
            HEL: HELO_1604(ttuD) HELO_3667
            MMW: Mmwyl1_0248 Mmwyl1_3064 Mmwyl1_3293
            TAU: Tola_0642
            CVI: CV_1724 CV_3660(ttuD)
            RSO: RSc0262 RSc0486(ttuD2) RSp1449(ttuD1)
            RSC: RCFBP_10195(ttuD) RCFBP_20996(ttuD) RCFBP_21231
            RSL: RPSI07_2881(ttuD) RPSI07_3152 RPSI07_mp1041 RPSI07_mp1426(ttuD)
            RPI: Rpic_0115 Rpic_0362 Rpic_3481
            RPF: Rpic12D_0122 Rpic12D_0377 Rpic12D_3154
            REU: Reut_A0152 Reut_A0463 Reut_A3294
            REH: H16_A0185 H16_A0478(ldhA) H16_A2132(ttuD2) H16_A3601(ttuD1)
                 H16_B0466(serA3)
            RME: Rmet_0118 Rmet_0405 Rmet_3451
            CTI: RALTA_A0128 RALTA_A0434(ttuD3) RALTA_A3055(ttuD2) RALTA_B0703
                 RALTA_B0888(ttuD2)
            BPS: BPSL0334
            BPM: BURPS1710b_0544
            BPL: BURPS1106A_0368(ghrA)
            BPD: BURPS668_0354(ghrA)
            BPR: GBP346_A0273
            BTE: BTH_I0314
            BVI: Bcep1808_3047 Bcep1808_6428
            BUR: Bcep18194_A6308
            BCN: Bcen_2344 Bcen_6449
            BCH: Bcen2424_2958 Bcen2424_6684
            BCM: Bcenmc03_2979 Bcenmc03_6281
            BCJ: BCAL0632 BCAS0384
            BAM: Bamb_3006 Bamb_4327 Bamb_6349
            BAC: BamMC406_2869 BamMC406_6053
            BMU: Bmul_2954
            BMJ: BMULJ_00280(serA)
            BXE: Bxe_A4269 Bxe_B1490
            BPH: Bphy_0166 Bphy_3184 Bphy_6567
            BPY: Bphyt_0441 Bphyt_6094
            BGL: bglu_1g32580 bglu_2g10310
            BGE: BC1002_0185 BC1002_4545
            PNU: Pnuc_1889
            BPE: BP2304
            BPA: BPP2425
            BBR: BB1874
            BPT: Bpet3096(ycdW1) Bpet4875(ycdW2)
            BAV: BAV2205
            AXY: AXYL_00754 AXYL_01281
            RFR: Rfer_2329 Rfer_3829
            POL: Bpro_0053 Bpro_0422 Bpro_1434 Bpro_4156
            PNA: Pnap_0476 Pnap_1018
            AAV: Aave_1113 Aave_2182 Aave_3758 Aave_4350
            AJS: Ajs_1122 Ajs_3758
            DIA: Dtpsy_1042 Dtpsy_3039
            VEI: Veis_0512 Veis_0928
            DAC: Daci_1407 Daci_2115 Daci_5635 Daci_5969
            VAP: Vapar_3921 Vapar_4717 Vapar_5231 Vapar_5630
            VPE: Varpa_0606 Varpa_4534 Varpa_5352
            CTT: CtCNB1_0508 CtCNB1_3712 CtCNB1_3749
            ADN: Alide_3101 Alide_3796
            MPT: Mpe_A0213 Mpe_A0976 Mpe_A3263
            HAR: HEAR0335
            MMS: mma_0382(ttuD)
            HSE: Hsero_1127(serA) Hsero_2486(serA)
            LCH: Lcho_3177 Lcho_4179
            TIN: Tint_2718 Tint_2855
            NEU: NE2456(ttuD2)
            NET: Neut_2458
            NMU: Nmul_A2230
            EBA: ebA4615(hfr)
            AZO: azo1162(ttuD)
            DAR: Daro_2118
            TBD: Tbd_0433
            APP: CAP2UW1_2071
            SLT: Slit_1785
            ANT: Arnit_0210
            GBM: Gbem_3609
            GEM: GM21_3717
            DVU: DVU0765
            DVL: Dvul_2205
            DVM: DvMF_2801
            DDE: Dde_2751
            DMA: DMR_28270(ttuD)
            DSA: Desal_0037
            DAS: Daes_2689
            BBA: Bd3195
            DOL: Dole_1573
            DAL: Dalk_0946
            DAT: HRM2_40640(ttuD)
            ADE: Adeh_3968
            ACP: A2cp1_4112
            AFW: Anae109_0452
            ANK: AnaeK_4079
            SCL: sce2998
            HOH: Hoch_2496 Hoch_3783 Hoch_4287
            SAT: SYN_00869
            SFU: Sfum_3915
            DBR: Deba_0515
            MLO: mll5489 mll7048 mlr5146
            MCI: Mesci_0071 Mesci_0361
            MES: Meso_2839 Meso_4079
            PLA: Plav_2031
            SME: SM_b20678(ttuD2) SMa1406(ttuD3) SMa1838 SMc04389(ttuD1)
            SMD: Smed_3163 Smed_3362 Smed_4311 Smed_5604
            RHI: NGR_b06370 NGR_b20390 NGR_c33150(ttuD2) NGR_c34780
            ATU: Atu3232 Atu3399 Atu4048 Atu5222 Atu5334
            ARA: Arad_0308 Arad_12372 Arad_3582(ttuD) Arad_7092 Arad_7363
                 Arad_7659(ttuD) Arad_9166
            AVI: Avi_0248 Avi_0477 Avi_5861 Avi_9119
            RET: RHE_CH01794(ttuD) RHE_PF00336(ypf00169)
            REC: RHECIAT_CH0000223 RHECIAT_CH0001882(ttuD) RHECIAT_PC0000540
            RLE: RL0994 RL2008 pRL120632
            RLT: Rleg2_1461 Rleg2_4136 Rleg2_4424
            RLG: Rleg_1644 Rleg_4450 Rleg_5028
            BME: BMEI1570 BMEI1939
            BMI: BMEA_A0005 BMEA_A0392
            BMF: BAB1_0005 BAB1_0384
            BMB: BruAb1_0005 BruAb1_0381
            BMC: BAbS19_I00050 BAbS19_I03550
            BMS: BR0005 BR0355
            BMT: BSUIS_A0005 BSUIS_A0386(ttuD)
            BOV: BOV_0005 BOV_0372
            BCS: BCAN_A0005 BCAN_A0363(ttuD)
            BMR: BMI_I360 BMI_I5
            OAN: Oant_0010 Oant_0461 Oant_4836
            BJA: bll6710 blr7830
            BRA: BRADO0973 BRADO1153 BRADO3422
            BBT: BBta_1916 BBta_4284 BBta_7083
            RPA: RPA1797
            RPB: RPB_1647 RPB_3567
            RPC: RPC_4629
            RPD: RPD_1897
            RPE: RPE_3720
            RPT: Rpal_2000
            RPX: Rpdx1_3733
            NHA: Nham_0659
            OCA: OCAR_7443
            XAU: Xaut_2571 Xaut_3104
            AZC: AZC_0324 AZC_2038 AZC_3359 AZC_3465
            SNO: Snov_3108 Snov_4156
            MEX: Mext_0771 Mext_2747
            MEA: Mex_1p2748 Mex_1p2944(gck)
            MDI: METDI1374 METDI3513(gck)
            MRD: Mrad2831_0126 Mrad2831_3212 Mrad2831_3223 Mrad2831_5498
            MET: M446_0667 M446_3560 M446_5205
            MPO: Mpop_2869 Mpop_4659
            MCH: Mchl_2974 Mchl_5683
            MNO: Mnod_0654 Mnod_1511 Mnod_2906 Mnod_5964
            BID: Bind_1721 Bind_2209
            MSL: Msil_1715
            HDN: Hden_2642
            RVA: Rvan_0616
            CSE: Cseg_2978
            PZU: PHZ_c2003
            AEX: Astex_2551
            SIL: SPO0415 SPO1564
            SIT: TM1040_0466 TM1040_3471
            RSP: RSP_3071 RSP_3442
            RSH: Rsph17029_3087 Rsph17029_3797
            RSQ: Rsph17025_2055 Rsph17025_3906
            RSK: RSKD131_3245 RSKD131_3608
            RCP: RCAP_rcc00798 RCAP_rcc02615(ttuD)
            JAN: Jann_3650 Jann_3926
            RDE: RD1_1204 RD1_1981(ttuD) RD1_3495 RD1_4241
            PDE: Pden_2195 Pden_4037 Pden_4963
            DSH: Dshi_0590 Dshi_3046(ttuD)
            KVU: EIO_1613
            ZMO: ZMO1883
            ZMN: Za10_1258
            NAR: Saro_2948 Saro_3775
            GOX: GOX1300
            GBE: GbCGDNIH1_0364
            ACR: Acry_1160 Acry_2372
            GDJ: Gdia_1589 Gdia_2170
            APT: APA01_00840 APA01_05700
            RRU: Rru_A2002 Rru_A2464
            RCE: RC1_2136(ttuD) RC1_3398
            MAG: amb3175
            AZL: AZL_026040 AZL_c03180
            APB: SAR116_1484 SAR116_2472
            CPY: Cphy_2103
            AFN: Acfer_1604
            EEL: EUBELI_01261
            ELM: ELI_2301
            BPB: bpr_I0130
            RXY: Rxyl_2854
            LIL: LA_2527(gckA)
            LBI: LEPBI_I2456
            LBF: LBF_2384
            ABA: Acid345_1043
            ACA: ACP_0262
            TSA: AciPR4_1527
            SUS: Acid_0778
            SRU: SRU_1550
            SRM: SRM_01748(ttuD)
            RMR: Rmar_0944
            CPI: Cpin_1502
            GFO: GFO_0312
            RBI: RB2501_14994
            ZPR: ZPR_3640
            FBC: FB2170_11281
            GAU: GAU_2625
            PSL: Psta_0794
            PLM: Plim_1831
            ACO: Amico_1239
            DLY: Dehly_0560
            RRS: RoseRS_1997
            RCA: Rcas_3272
            CAU: Caur_0619
            CAG: Cagg_3389
            CHL: Chy400_0669
            HAU: Haur_4017
            TRO: trd_1031
            STI: Sthe_0502
            ATM: ANT_25230
            DRA: DR_1157
            DGE: Dgeo_2615
            DDR: Deide_1p01720
            TRA: Trad_2945
            TTH: TTC0124
            TTJ: TTHA0500
            TSC: TSC_c05380(ttuD)
            MRB: Mrub_2759
            MSV: Mesil_1425
            OPR: Ocepr_1765
            PMX: PERMA_1579
            TMA: TM1585
            TPT: Tpet_1207
            TLE: Tlet_1724
            TRQ: TRQ2_1248
            TNA: CTN_1169
            TNP: Tnap_1223
            TME: Tmel_0085
            TAF: THA_302
            FNO: Fnod_1253
            PMO: Pmob_0534
            KOL: Kole_1768
            DTH: DICTH_0141
            NDE: NIDE0496(ttuD)
            TTR: Tter_0099
            DDF: DEFDS_1959
            DAP: Dacet_2927
            MPD: MCP_1988
            APO: Arcpr_0243
            HMA: pNG7015(ttuD)
            HWA: HQ1667A(gckA)
            NPH: NP1162A
            HLA: Hlac_0380
            HUT: Huta_2454
            HMU: Hmuk_3413
            HTU: Htur_2421
            NMG: Nmag_0806
            HVO: HVO_1553(ttuD)
            HJE: HacjB3_12580
            HBO: Hbor_16760
            TON: TON_1228
            TGA: TGAM_1557(ttuD)
            TSI: TSIB_1605
            TBA: TERMP_00811
            ABI: Aboo_0604
            RCI: RCIX2676(ttuD)
            SMR: Smar_0737
            SHC: Shell_0054
            IAG: Igag_0369
            SIS: LS215_1579
            SIA: M1425_1471
            SIM: M1627_1586
            SID: M164_1468
            SIY: YG5714_1475
            SIN: YN1551_1361
            SII: LD85_1678
            MSE: Msed_2013
            PAS: Pars_0472
            CMA: Cmaq_0816
            VDI: Vdis_1804
            TPE: Tpen_0207
            ASC: ASAC_1021
            NMR: Nmar_1111
            CSY: CENSYa_0799
            KCR: Kcr_1277
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.81
            IUBMB Enzyme Nomenclature: 1.1.1.81
            ExPASy - ENZYME nomenclature database: 1.1.1.81
            BRENDA, the Enzyme Database: 1.1.1.81
            CAS: 9059-44-3
///
ENTRY       EC 1.1.1.82                 Enzyme
NAME        malate dehydrogenase (NADP+);
            NADP+-malic enzyme;
            NADP+-malate dehydrogenase;
            malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
            malate NADP+ dehydrogenase;
            NADP+ malate dehydrogenase;
            NADP+-linked malate dehydrogenase;
            malate dehydrogenase (NADP+)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-malate:NADP+ oxidoreductase
REACTION    (S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:R00343]
ALL_REAC    R00343
SUBSTRATE   (S)-malate [CPD:C00149];
            NADP+ [CPD:C00006]
PRODUCT     oxaloacetate [CPD:C00036];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
EFFECTOR    hn [CPD:C00205]
COMMENT     Activated by light.
REFERENCE   1  [PMID:5689906]
  AUTHORS   Connelly JL, Danner DJ, Bowden JA.
  TITLE     Branched chain alpha-keto acid metabolism. I. Isolation,
            purification, and partial characterization of bovine liver
            alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid
            dehydrogenase.
  JOURNAL   J. Biol. Chem. 243 (1968) 1198-203.
  ORGANISM  Bos taurus [GN:bta]
REFERENCE   2  [PMID:4397919]
  AUTHORS   Johnson HS.
  TITLE     NADP-malate dehydrogenase: photoactivation in leaves of plants with
            Calvin cycle photosynthesis.
  JOURNAL   Biochem. Biophys. Res. Commun. 43 (1971) 703-9.
  ORGANISM  Zea mays [GN:zma]
REFERENCE   3  [PMID:4395182]
  AUTHORS   Johnson HS, Hatch MD.
  TITLE     Properties and regulation of leaf nicotinamide-adenine dinucleotide
            phosphate-malate dehydrogenase and 'malic' enzyme in plants with the
            C4-dicarboxylic acid pathway of photosynthesis.
  JOURNAL   Biochem. J. 119 (1970) 273-80.
  ORGANISM  Zea mays [GN:zma]
PATHWAY     ec00620  Pyruvate metabolism
            ec00710  Carbon fixation in photosynthetic organisms
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00051  malate dehydrogenase (NADP+)
GENES       CGL: NCgl0631(cgl0661)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.82
            IUBMB Enzyme Nomenclature: 1.1.1.82
            ExPASy - ENZYME nomenclature database: 1.1.1.82
            BRENDA, the Enzyme Database: 1.1.1.82
            CAS: 37250-19-4
///
ENTRY       EC 1.1.1.83                 Enzyme
NAME        D-malate dehydrogenase (decarboxylating);
            D-malate dehydrogenase;
            D-malic enzyme;
            bifunctional L(+)-tartrate dehydrogenase-D(+)-malate
            (decarboxylating)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-malate:NAD+ oxidoreductase (decarboxylating)
REACTION    (R)-malate + NAD+ = pyruvate + CO2 + NADH [RN:R00215]
ALL_REAC    R00215
SUBSTRATE   (R)-malate [CPD:C00497];
            NAD+ [CPD:C00003]
PRODUCT     pyruvate [CPD:C00022];
            CO2 [CPD:C00011];
            NADH [CPD:C00004]
REFERENCE   1  [PMID:4889267]
  AUTHORS   Stern JR, O'Brien RW.
  TITLE     Oxidation D-malic and beta-alkylmalic acids wild-type and mutant
            strains of Salmonella typhimurium and by Aerobacter aerogenes.
  JOURNAL   J. Bacteriol. 98 (1969) 147-51.
  ORGANISM  Salmonella typhimurium, Klebsiella pneumoniae [GN:kpn]
PATHWAY     ec00650  Butanoate metabolism
ORTHOLOGY   K07246  tartrate dehydrogenase/decarboxylase / D-malate
                    dehydrogenase
GENES       ECO: b1800(dmlA)
            ECJ: JW1789(yeaU)
            ECD: ECDH10B_1938(yeaU)
            EBW: BWG_1613(yeaU)
            ECE: Z2843(yeaU)
            ECS: ECs2509
            ECF: ECH74115_2526(ttuC)
            ETW: ECSP_2372(yeaU)
            EOJ: ECO26_2569(yeaU)
            EOI: ECO111_2306(yeaU)
            EOH: ECO103_1989(yeaU)
            EOK: G2583_2247(yeaU)
            ECX: EcHS_A1888(ttuC)
            ECW: EcE24377A_2026(ttuC)
            ECM: EcSMS35_1388(ttuC)
            ECY: ECSE_1974
            ECR: ECIAI1_1869(yeaU)
            ECK: EC55989_1973(yeaU)
            ECT: ECIAI39_1253(yeaU)
            EUM: ECUMN_2090(yeaU)
            ECL: EcolC_1833
            EBR: ECB_01770(yeaU)
            EBD: ECBD_1842
            YPE: YPO2496
            YPK: y1692
            YPA: YPA_1991
            YPN: YPN_2090
            YPM: YP_2311(leuB1)
            YPP: YPDSF_1907
            YPG: YpAngola_A1756
            YPZ: YPZ3_2138
            YPS: YPTB2532
            YPI: YpsIP31758_1512
            YPY: YPK_1616
            YPB: YPTS_2627
            SSN: SSON_1361(yeaU)
            SBO: SBO_1288(yeaU)
            SBC: SbBS512_E2058(ttuC)
            SDY: SDY_1701(yeaU)
            EBI: EbC_44840(ttuC\')
            ESC: Entcl_2813
            KPN: KPN_01015
            KPE: KPK_3185(ttuC) KPK_3545
            KPU: KP1_1998 KP1_2292
            KVA: Kvar_3059 Kvar_3364
            CKO: CKO_01178
            CRO: ROD_11931(ttuC') ROD_18421
            DDA: Dd703_3166
            DDC: Dd586_0850
            DDD: Dda3937_01460(yeaU)
            DZE: Dd1591_3237
            XNE: XNC1_0562(yeaU)
            PAM: PANA_0325(yeaU)
            PVA: Pvag_3587(yeaU) Pvag_pPag30035(ttuC)
            PAO: Pat9b_0374 Pat9b_4594
            MSU: MS1105(leuB)
            PPG: PputGB1_2196
            PPW: PputW619_1230
            PST: PSPTO_2662
            PSB: Psyr_2396
            PSP: PSPPH_1578 PSPPH_2554
            PFL: PFL_3649
            PFS: PFLU4038
            PEN: PSEEN2132
            ACD: AOLE_15445
            ACB: A1S_0849
            ABY: ABAYE2964
            ABC: ACICU_00802
            ABN: AB57_0897
            ABB: ABBFA_002763
            MAQ: Maqu_2209
            AEH: Mlg_0489
            HHA: Hhal_0829
            CSA: Csal_2776
            HEL: HELO_1564(yeaU)
            ABO: ABO_0510(tdh)
            MMW: Mmwyl1_3080
            RSO: RSp0996(ttuC2) RSp1612(ttuC)
            RSL: RPSI07_mp0990 RPSI07_mp1032 RPSI07_mp1717
            REU: Reut_A0462 Reut_B4115 Reut_C5899
            REH: H16_A0477(leuB1) H16_A2133(leuB2)
            RME: Rmet_0404
            CTI: RALTA_A0433(ttuC3) RALTA_B0889(ttuC1)
            BMA: BMAA0011(ttuC)
            BMV: BMASAVP1_1159(ttuC)
            BML: BMA10229_1440(ttuC)
            BMN: BMA10247_A0014(ttuC)
            BPS: BPSS0011
            BPM: BURPS1710b_A1518
            BPL: BURPS1106A_A0014
            BPD: BURPS668_A0015
            BTE: BTH_II0013
            BVI: Bcep1808_3784
            BUR: Bcep18194_B3173
            BCN: Bcen_4654 Bcen_5152 Bcen_5538
            BCH: Bcen2424_3709 Bcen2424_5707 Bcen2424_5903
            BCM: Bcenmc03_3812 Bcenmc03_4532
            BCJ: BCAM0016 BCAM0743 BCAS0278
            BAM: Bamb_4976 Bamb_5440
            BAC: BamMC406_3119 BamMC406_3593
            BMU: Bmul_5024 Bmul_5317 Bmul_6024
            BMJ: BMULJ_03204(ttuC) BMULJ_03491(ttuC) BMULJ_05503(ttuC)
            BXE: Bxe_B1486 Bxe_B1620 Bxe_C0769 Bxe_C1229
            BPH: Bphy_4849 Bphy_5655 Bphy_6571
            BPY: Bphyt_5037 Bphyt_6098
            BGL: bglu_2g00150
            BGE: BC1002_3331 BC1002_4548 BC1002_5049
            PNU: Pnuc_1028
            PNE: Pnec_0838
            BPE: BP2291
            BPA: BPP2437 BPP4066
            BBR: BB1886 BB4539
            BPT: Bpet3077(yeaU1) Bpet4476(yeaU2)
            BAV: BAV2193
            AXY: AXYL_02112 AXYL_05245
            RFR: Rfer_0440 Rfer_0845 Rfer_2247
            POL: Bpro_1432 Bpro_3066
            PNA: Pnap_1016 Pnap_1632
            AAV: Aave_2087 Aave_2191
            AJS: Ajs_1120 Ajs_2860
            DIA: Dtpsy_1040 Dtpsy_2349
            VEI: Veis_2698 Veis_3186
            DAC: Daci_2113 Daci_2360
            VAP: Vapar_1027 Vapar_1788 Vapar_5638
            VPE: Varpa_0614 Varpa_1963 Varpa_4346 Varpa_5965
            CTT: CtCNB1_3465
            ADN: Alide_2759 Alide_3103
            MPT: Mpe_A0251
            HAR: HEAR3229(yeaU)
            MMS: mma_1237(ttuC)
            HSE: Hsero_1469(ttuC)
            LCH: Lcho_2992 Lcho_3176
            TIN: Tint_1132
            AZO: azo3860(yeaU)
            MLO: mll7044
            MES: Meso_4538
            PLA: Plav_0534
            SME: SMa1846
            SMD: Smed_5601
            RHI: NGR_b06350 NGR_b06550(ttuC)
            ATU: Atu3402
            ARA: Arad_7660 Arad_9169
            AVI: Avi_9120
            RET: RHE_PF00339(ypf00171)
            REC: RHECIAT_PC0000543
            RLE: RL0995 pRL110153(ttuC) pRL120629
            RLT: Rleg2_4411 Rleg2_4999 Rleg2_5311
            RLG: Rleg_5025
            BJA: blr2916 blr6570
            BRA: BRADO2534(yeaU) BRADO5094(ttuC)
            BBT: BBta_2879(yeaU) BBta_5565(ttuC)
            RPA: RPA1742(yeaU)
            RPB: RPB_3626
            RPC: RPC_4630
            RPD: RPD_1841
            RPT: Rpal_1942
            RPX: Rpdx1_3789
            OCA: OCAR_4377 OCAR_5921
            SNO: Snov_1602 Snov_1606
            MEX: Mext_4687
            MEA: Mex_1p5136(ttuC)
            MDI: METDI1373(ttuC) METDI5741(ttuC)
            MRD: Mrad2831_0770 Mrad2831_3993
            MET: M446_5246 M446_6783
            MPO: Mpop_4658 Mpop_5230
            MCH: Mchl_5152
            MNO: Mnod_1445 Mnod_5811
            CSE: Cseg_2987
            RSP: RSP_3388 RSP_3389 RSP_4031
            RSH: Rsph17029_3034 Rsph17029_3035
            RSK: RSKD131_3554 RSKD131_3555 RSKD131_4374
            PDE: Pden_4970
            DSH: Dshi_0775(ttuC)
            NAR: Saro_2935 Saro_3895
            ACR: Acry_0182 Acry_0647
            GDI: GDI_0420
            GDJ: Gdia_1585
            MAG: amb3176
            AZL: AZL_c03210(ttuC)
            APB: SAR116_0317 SAR116_1679
            BSU: BSU04000(ycsA)
            BSS: BSUW23_02070(ycsA)
            BHA: BH1070
            BCY: Bcer98_0765
            BLI: BL03389(ycsA)
            BLD: BLi03766(ycsA)
            BAY: RBAM_006090(ycsA)
            BAO: BAMF_0508(ycsA)
            BAE: BATR1942_18405
            BCL: ABC0841
            BPU: BPUM_0399(ycsA)
            BPF: BpOF4_11105
            BMQ: BMQ_1960(ycsA)
            BMD: BMD_1915(ycsA)
            OIH: OB0661
            GTN: GTNG_0291 GTNG_3379
            GMC: GY4MC1_3777
            LSP: Bsph_2213
            BBE: BBR47_56490
            BTS: Btus_3059
            CCE: Ccel_2567
            AMT: Amet_4274
            STH: STH2344
            AFN: Acfer_1764
            DSY: DSY3587
            DHD: Dhaf_1796
            MSM: MSMEG_1986
            MAB: MAB_4419
            MMC: Mmcs_2573
            MKM: Mkms_2618
            MJL: Mjls_2612
            RHA: RHA1_ro04803 RHA1_ro08803
            ROP: ROP_48970
            ACH: Achl_0442
            NDA: Ndas_0828 Ndas_1797
            SEN: SACE_3495(leuB1) SACE_4608
            SVI: Svir_30170
            AMD: AMED_7876(ttuC)
            SNA: Snas_1914 Snas_4827
            RXY: Rxyl_1183
            CWO: Cwoe_1031
            SUS: Acid_1530
            IPO: Ilyop_2603
            GAU: GAU_3552
            PSL: Psta_3744
            TRO: trd_1342
            STI: Sthe_3519
            KOL: Kole_0991
            HJE: HacjB3_03310 HacjB3_09780
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.83
            IUBMB Enzyme Nomenclature: 1.1.1.83
            ExPASy - ENZYME nomenclature database: 1.1.1.83
            BRENDA, the Enzyme Database: 1.1.1.83
            CAS: 37250-20-7
///
ENTRY       EC 1.1.1.84                 Enzyme
NAME        dimethylmalate dehydrogenase;
            beta,beta-dimethylmalate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)
REACTION    (R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH
            [RN:R01211]
ALL_REAC    R01211
SUBSTRATE   (R)-3,3-dimethylmalate [CPD:C01088];
            NAD+ [CPD:C00003]
PRODUCT     3-methyl-2-oxobutanoate [CPD:C00141];
            CO2 [CPD:C00011];
            NADH [CPD:C00004]
COFACTOR    NH3 [CPD:C00014];
            Manganese [CPD:C00034];
            Cobalt ion [CPD:C00175];
            Potassium [CPD:C00238];
            NH4+ [CPD:C01342]
COMMENT     Requires K+ or NH4+ and Mn2+ or Co2+; also acts on (R)-malate.
REFERENCE   1  [PMID:4287371]
  AUTHORS   Magee PT, Snell EE.
  TITLE     The bacterial degradation of pantothenic acid. IV. Enzymatic
            conversion of aldopantoate to alpha-ketoisovalerate.
  JOURNAL   Biochemistry. 5 (1966) 409-16.
  ORGANISM  Pseudomonas sp.
PATHWAY     ec00770  Pantothenate and CoA biosynthesis
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.84
            IUBMB Enzyme Nomenclature: 1.1.1.84
            ExPASy - ENZYME nomenclature database: 1.1.1.84
            BRENDA, the Enzyme Database: 1.1.1.84
            CAS: 37250-21-8
///
ENTRY       EC 1.1.1.85                 Enzyme
NAME        3-isopropylmalate dehydrogenase;
            beta-isopropylmalic enzyme;
            beta-isopropylmalate dehydrogenase;
            threo-Ds-3-isopropylmalate dehydrogenase;
            3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
REACTION    (1) (1a) (2R,3S)-3-isopropylmalate + NAD+ =
            (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ [RN:R04426];
            (2) (1b) (2S)-2-isopropyl-3-oxosuccinate = 4-methyl-2-oxopentanoate
            + CO2 (spontaneous)
ALL_REAC    R04426;
            (other) R00994
SUBSTRATE   (2R,3S)-3-isopropylmalate [CPD:C04411];
            NAD+ [CPD:C00003];
            (2S)-2-isopropyl-3-oxosuccinate [CPD:C04236]
PRODUCT     (2S)-2-isopropyl-3-oxosuccinate [CPD:C04236];
            NADH [CPD:C00004];
            H+ [CPD:C00080];
            4-methyl-2-oxopentanoate [CPD:C00233];
            CO2 [CPD:C00011]
COMMENT     The product decarboxylates spontaneously to yield
            4-methyl-2-oxopentanoate.
REFERENCE   1  [PMID:14087358]
  AUTHORS   BURNS RO, UMBARGER HE, GROSS SR
  TITLE     THE BIOSYNTHESIS OF LEUCINE. III. THE CONVERSION OF
            ALPHA-HYDROXY-BETA-CARBOXYISOCAPROATE TO ALPHA-KETOISOCAPROATE.
  JOURNAL   Biochemistry. 2 (1963) 1053-8.
REFERENCE   2  [PMID:4889950]
  AUTHORS   Parsons SJ, Burns RO.
  TITLE     Purification and properties of beta-isopropylmalate dehydrogenase.
  JOURNAL   J. Biol. Chem. 244 (1969) 996-1003.
  ORGANISM  Salmonella typhimurium [GN:stm]
REFERENCE   3  [PMID:10683439]
  AUTHORS   Nemeth A, Svingor A, Pocsik M, Dobo J, Magyar C, Szilagyi A, Gal P,
            Zavodszky P.
  TITLE     Mirror image mutations reveal the significance of an intersubunit
            ion cluster in the stability of 3-isopropylmalate dehydrogenase.
  JOURNAL   FEBS. Lett. 468 (2000) 48-52.
  ORGANISM  Escherichia coli [GN:eco], Thermus thermophilus [GN:ttj]
REFERENCE   4  [PMID:14269331]
  AUTHORS   CALVO JM, STEVENS CM, KALYANPUR MG, UMBARGER HE.
  TITLE     THE ABSOLUTE CONFIGURATION OF ALPHA-HYDROXY-BETA-CARBOXYISOCAPROIC
            ACID (3-ISOPROPYLMALIC ACID), AN INTERMEDIATE IN LEUCINE
            BIOSYNTHESIS.
  JOURNAL   Biochemistry. 19 (1964) 2024-7.
  ORGANISM  Neurospora crassa [GN:ncr]
PATHWAY     ec00290  Valine, leucine and isoleucine biosynthesis
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00052  3-isopropylmalate dehydrogenase
GENES       ATH: AT1G31180 AT1G80560 AT5G14200
            POP: POPTR_1067569
            RCU: RCOM_0011000
            VVI: 100259968
            OSA: 4333613
            SBI: SORBI_06g033720
            ZMA: 100283376 100284589(cl362_2b)
            PPP: PHYPADRAFT_115152
            CRE: CHLREDRAFT_195906(LEU3b)
            VCN: VOLCADRAFT_106647
            OLU: OSTLU_29616
            OTA: Ot14g03440
            CME: CMM229C
            SCE: YCL018W(LEU2)
            AGO: AGOS_AAL012C
            KLA: KLLA0D04906g
            LTH: KLTH0H12188g
            PPA: PAS_chr3_0039
            VPO: Kpol_1048p63
            ZRO: ZYRO0E04796g
            CGR: CAGL0H03795g
            DHA: DEHA2G10978g
            PIC: PICST_68561(LEU2)
            PGU: PGUG_04278
            LEL: LELG_05559
            CAL: CaO19.7080(LEU2) CaO19_7080(CaJ7_0053)
            CTP: CTRG_04924
            CDU: CD36_70610(LEU2)
            CLU: CLUG_05354
            NCR: NCU06232
            PAN: PODANSg5277
            MGR: MGG_05223(MG05223.4) MGG_09813(MG09813.4)
            FGR: FG06675.1 FG10671.1
            SSL: SS1G_07102
            BFU: BC1G_14880
            ANI: AN0912.2
            AFM: AFUA_1G15780 AFUA_6G13590
            NFI: NFIA_009550 NFIA_059550
            AOR: AO090005001122
            ANG: An01g14130(leu2A)
            AFV: AFLA_009040 AFLA_083640
            ACT: ACLA_019590 ACLA_086890
            PCS: Pc16g13350 Pc22g00840
            CIM: CIMG_03106 CIMG_08476
            CPW: CPC735_010410 CPC735_061440
            URE: UREG_02552 UREG_02851
            PNO: SNOG_02041
            TML: GSTUM_00006378001
            SPO: SPBC1A4.02c(leu1)
            CNE: CNA04310
            CNB: CNBA4140
            PPL: POSPLDRAFT_104910
            LBC: LACBIDRAFT_231016
            MPR: MPER_02541
            CCI: CC1G_01358
            SCM: SCHCODRAFT_80432
            UMA: UM01245.1
            MGL: MGL_0905
            ECO: b0073(leuB)
            ECJ: JW5807(leuB)
            EBW: BWG_0069(leuB)
            ECE: Z0082(leuB)
            ECS: ECs0077
            ECF: ECH74115_0080(leuB)
            ETW: ECSP_0077(leuB)
            EOJ: ECO26_0076(leuB)
            EOI: ECO111_0076(leuB)
            EOH: ECO103_0075(leuB)
            ECG: E2348C_0078(leuB)
            EOK: G2583_0077(leuB)
            ECC: c0090(leuB)
            ECP: ECP_0075
            ECI: UTI89_C0080(leuB)
            ECV: APECO1_1910(leuB)
            ECX: EcHS_A0078(leuB)
            ECW: EcE24377A_0076(leuB)
            ECM: EcSMS35_0078(leuB)
            ECY: ECSE_0073
            ECR: ECIAI1_0074(leuB)
            ECQ: ECED1_0073(leuB)
            ECK: EC55989_0071(leuB)
            ECT: ECIAI39_0078(leuB)
            EUM: ECUMN_0075(leuB)
            ECZ: ECS88_0078(leuB)
            ECL: EcolC_3584
            EBR: ECB_00075(leuB)
            EBD: ECBD_3543
            EFE: EFER_0095(leuB)
            STY: STY0131(leuB)
            STT: t0116(leuB)
            STM: STM0112(leuB)
            SPT: SPA0114(leuB)
            SEK: SSPA0110
            SPQ: SPAB_00142
            SEI: SPC_0121(leuB)
            SEC: SC0108(leuB)
            SEH: SeHA_C0123(leuB)
            SEE: SNSL254_A0124(leuB)
            SEW: SeSA_A0128(leuB)
            SEA: SeAg_B0128(leuB)
            SED: SeD_A0121(leuB)
            SEG: SG0114(leuB)
            SET: SEN0113(leuB)
            SES: SARI_02890
            YPE: YPO0532(leuB)
            YPK: y3646(leuB)
            YPA: YPA_3565
            YPN: YPN_0402
            YPM: YP_3650(leuB2)
            YPP: YPDSF_3107
            YPG: YpAngola_A2937(leuB)
            YPZ: YPZ3_0514
            YPS: YPTB0671(leuB)
            YPI: YpsIP31758_3406(leuB)
            YPY: YPK_3536
            YPB: YPTS_0697
            YEN: YE0653(leuB)
            SFL: SF0068(leuB)
            SFX: S0070(leuB)
            SFV: SFV_0065(leuB)
            SSN: SSON_0080(leuB)
            SBO: SBO_0060(leuB)
            SBC: SbBS512_E0067(leuB)
            SDY: SDY_0100(leuB)
            ECA: ECA3832(leuB)
            PCT: PC1_3608
            PWA: Pecwa_3796
            ETA: ETA_07410(leuB)
            EPY: EpC_07280(leuB)
            EAM: EAMY_2907(leuB)
            EAY: EAM_0682(leuB)
            EBI: EbC_07060(leuB)
            PLU: plu3674(leuB)
            PAY: PAU_01096(leuB)
            BUC: BUpL05(leuB)
            BAB: bbp496(leuB)
            BCC: pLeuBCc_003(leuB)
            SGL: SG0436
            ENT: Ent638_0621
            ENC: ECL_00871
            ESC: Entcl_3651
            ESA: ESA_03265
            CTU: Ctu_07060(leuB)
            KPN: KPN_00079(leuB)
            KPE: KPK_4663(leuB)
            KPU: KP1_0895(leuB)
            KVA: Kvar_4304
            CKO: CKO_03305
            CRO: ROD_00811(leuB) ROD_12401
            SPE: Spro_0744
            PMR: PMI2085(leuB)
            EIC: NT01EI_0719
            ETR: ETAE_0620(leuB)
            BFL: Bfl132(leuB)
            BPN: BPEN_136(leuB)
            BVA: BVAF_133(leuB)
            DDA: Dd703_0631
            DDC: Dd586_3548
            DDD: Dda3937_04404(leuB)
            DZE: Dd1591_0593
            XBO: XBJ1_3494(leuB)
            XNE: XNC1_1040(leuB)
            PAM: PANA_0705(leuB)
            PVA: Pvag_0107(leuB)
            PAO: Pat9b_0649
            HIN: HI0987(leuB)
            HIT: NTHI1161(leuB)
            HIP: CGSHiEE_07030
            HIF: HIBPF12610
            HIL: HICON_04130
            HAP: HAPS_0030(leuB)
            HSO: HS_0391(leuB)
            HSM: HSM_0716
            PMU: PM1961(leuB)
            MSU: MS0598(leuB)
            APL: APL_0432(leuB)
            APJ: APJL_0458(leuB)
            APA: APP7_0507
            ASU: Asuc_1908
            AAP: NT05HA_1565
            XFA: XF2372
            XFT: PD1397(leuB)
            XFM: Xfasm12_1539
            XFN: XfasM23_1483
            XCC: XCC3328(leuB)
            XCB: XC_0836
            XCA: xccb100_0869(leuB)
            XCV: XCV3584(leuB)
            XAC: XAC3456(leuB)
            XOO: XOO0940(leuB)
            XOM: XOO_0860
            XOP: PXO_02610(leuB)
            XAL: XALc_0751(leuB)
            SML: Smlt3921(leuB)
            SMT: Smal_3336
            PSU: Psesu_0439
            VCH: VC2491
            VCO: VC0395_A2066(leuB)
            VCM: VCM66_2413(leuB)
            VCJ: VCD_001865
            VVU: VV1_0655
            VVY: VV0486
            VVM: VVM_04233
            VPA: VP0344
            VHA: VIBHAR_00816
            VSP: VS_0379
            VEX: VEA_001657
            VFI: VF_0294(leuB)
            VFM: VFMJ11_0282(leuB)
            VSA: VSAL_I0376(leuB)
            PPR: PBPRA0418
            PAE: PA3118(leuB)
            PAU: PA14_23790(leuB)
            PAP: PSPA7_2015(leuB)
            PAG: PLES_19411(leuB)
            PPU: PP_1988(leuB)
            PPF: Pput_3771
            PPG: PputGB1_1519
            PPW: PputW619_1551
            PST: PSPTO_2175(leuB)
            PSB: Psyr_1985
            PSP: PSPPH_1954(leuB) PSPPH_2159
            PFL: PFL_2066(leuB)
            PFO: Pfl01_1892
            PFS: PFLU4193
            PEN: PSEEN1652(leuB)
            PMY: Pmen_2721
            PSA: PST_1774(leuB)
            CJA: CJA_1746(leuB)
            AVN: Avin_34260(leuB)
            PAR: Psyc_1410(leuB)
            PCR: Pcryo_1571
            PRW: PsycPRwf_1934
            ACI: ACIAD0469(leuB)
            ACD: AOLE_17335
            ACB: A1S_0420
            ABM: ABSDF3095(leuB)
            ABY: ABAYE3357(leuB)
            ABC: ACICU_00428
            ABN: AB57_0497(leuB)
            ABB: ABBFA_003116(leuB)
            MCT: MCR_1022(leuB)
            SON: SO_4235(leuB)
            SDN: Sden_0335
            SFR: Sfri_3819
            SAZ: Sama_0336
            SBL: Sbal_0387
            SBM: Shew185_0386
            SBN: Sbal195_0398
            SBP: Sbal223_0412
            SLO: Shew_3471
            SPC: Sputcn32_0472
            SSE: Ssed_0394
            SPL: Spea_3827
            SHE: Shewmr4_3587
            SHM: Shewmr7_0369
            SHN: Shewana3_3760
            SHW: Sputw3181_0375
            SHL: Shal_0439
            SWD: Swoo_4549
            SWP: swp_2214
            SVO: SVI_4049(leuB)
            CPS: CPS_4209(leuB)
            PHA: PSHAa2893(leuB)
            PAT: Patl_3269
            PSM: PSM_A2985(leuB)
            SDE: Sde_2084
            MAQ: Maqu_1563
            AMC: MADE_03086
            PIN: Ping_2229
            TTU: TERTU_2500(leuB)
            FBL: Fbal_3682
            MCA: MCA2063(leuB)
            FTL: FTL_1887
            FTN: FTN_0059(leuB)
            FPH: Fphi_0772
            TCX: Tcr_0797
            NOC: Noc_1014
            NHL: Nhal_1962
            NWA: Nwat_2019
            ALV: Alvin_1606
            AEH: Mlg_1230 Mlg_2362
            HHA: Hhal_1810
            TGR: Tgr7_1247
            TKM: TK90_1341
            HNA: Hneap_1716
            HCH: HCH_02430(leuB)
            CSA: Csal_2451
            HEL: HELO_2234(leuB)
            ABO: ABO_1467(leuB)
            KKO: Kkor_0977
            MMW: Mmwyl1_2093
            AHA: AHA_0881(leuB)
            ASA: ASA_3410(leuB)
            TAU: Tola_0681
            AFE: Lferr_1732
            AFR: AFE_2075(leuB)
            CRP: CRP_082
            RMA: Rmag_0099
            VOK: COSY_0103(leuB)
            GPB: HDN1F_16210(leuB)
            NMA: NMA1456(leuB)
            NME: NMB1031(leuB)
            NMC: NMC1182(leuB)
            NMN: NMCC_1164(leuB)
            NMI: NMO_1097(leuB)
            NGO: NGO0674
            NGK: NGK_1232
            NLA: NLA_10860(leuB)
            CVI: CV_2778(leuB)
            LHK: LHK_01242(leuB)
            RSO: RSc1988(leuB1) RSp0329(leuB2)
            RSC: RCFBP_11397(leuB)
            RSL: RPSI07_1441(leuB)
            RPI: Rpic_2143
            RPF: Rpic12D_1819
            REU: Reut_A2311
            REH: H16_A2619(leuB3)
            RME: Rmet_2472
            CTI: RALTA_A2118(leuB)
            BMA: BMAA1726(leuB)
            BMV: BMASAVP1_1643(leuB)
            BML: BMA10229_1852(leuB)
            BMN: BMA10247_A0523(leuB)
            BPS: BPSS1705(leuB)
            BPM: BURPS1710b_A0775(leuB)
            BPL: BURPS1106A_A2313(leuB)
            BPD: BURPS668_A2451(leuB)
            BTE: BTH_II0674(leuB)
            BVI: Bcep1808_4457
            BUR: Bcep18194_B2131
            BCN: Bcen_4415
            BCH: Bcen2424_3952
            BCM: Bcenmc03_3576
            BCJ: BCAM0985(leuB)
            BAM: Bamb_3343
            BAC: BamMC406_3847
            BMU: Bmul_4627
            BMJ: BMULJ_03884(leuB)
            BXE: Bxe_B2887
            BPH: Bphy_4369
            BPY: Bphyt_6847
            BGL: bglu_2g08360
            BGE: BC1002_5206
            BRH: RBRH_00179
            PNU: Pnuc_0767
            PNE: Pnec_1054
            BPE: BP1483(leuB)
            BPA: BPP1944(leuB)
            BBR: BB1014(leuB) BB2132(leuB)
            BPT: Bpet3035(leuB)
            BAV: BAV2268(leuB)
            AXY: AXYL_02236(leuB1) AXYL_03894(leuB2)
            TEQ: TEQUI_1482
            RFR: Rfer_1793
            POL: Bpro_3610
            PNA: Pnap_3041
            AAV: Aave_1221
            AJS: Ajs_3233
            DIA: Dtpsy_2586
            VEI: Veis_1047 Veis_1349
            DAC: Daci_5238
            VAP: Vapar_1420 Vapar_6279
            VPE: Varpa_1565 Varpa_4883
            CTT: CtCNB1_1005
            ADN: Alide_0827 Alide_3142
            MPT: Mpe_A2162
            HAR: HEAR1217(leuB)
            MMS: mma_2169(leuB)
            HSE: Hsero_3297(leuB)
            LCH: Lcho_1677
            TIN: Tint_2329
            NEU: NE0688(leuB)
            NET: Neut_1147
            NMU: Nmul_A1918
            EBA: ebA4760(leuB)
            AZO: azo1041(leuB)
            DAR: Daro_0864 Daro_3775
            TMZ: Tmz1t_3068
            TBD: Tbd_1920
            MFA: Mfla_1703
            MMB: Mmol_0974
            MEH: M301_1172
            MEI: Msip34_1551
            MEP: MPQ_1616(leuB)
            APP: CAP2UW1_0184 CAP2UW1_1223
            SLT: Slit_2122
            GCA: Galf_0493
            HHE: HH1134(leuB)
            HMS: HMU10170(leuB)
            WSU: WS1813
            TDN: Suden_1101
            SKU: Sulku_0987
            CJE: Cj1718c(leuB)
            CJR: CJE1888(leuB)
            CJJ: CJJ81176_0016(leuB)
            CJU: C8J_1624(leuB)
            CJN: ICDCCJ_1623
            CJD: JJD26997_2095(leuB)
            CFF: CFF8240_1020(leuB)
            CCV: CCV52592_1365(leuB)
            CHA: CHAB381_1264(leuB)
            CCO: CCC13826_0036(leuB)
            ABU: Abu_1013(leuB)
            ANT: Arnit_1417
            SDL: Sdel_1516
            NIS: NIS_0727(leuB)
            SUN: SUN_1705(leuB)
            NSA: Nitsa_0614
            NAM: NAMH_1248(leuB)
            GSU: GSU2879(leuB)
            GME: Gmet_0602
            GUR: Gura_1045
            GLO: Glov_0348
            GBM: Gbem_0908
            GEO: Geob_3653
            GEM: GM21_3353
            PCA: Pcar_1904(leuB)
            PPD: Ppro_0045
            DVU: DVU2985(leuB)
            DVL: Dvul_0387
            DVM: DvMF_1794
            DDE: Dde_3222
            DDS: Ddes_0509
            DMA: DMR_16010(leuB)
            DSA: Desal_1585
            DAS: Daes_1909
            DBA: Dbac_1740
            DRT: Dret_1100
            DPS: DP1284
            DAK: DaAHT2_0936
            DPR: Despr_0909
            DOL: Dole_2219
            DAL: Dalk_1240
            DAT: HRM2_04430(leuB)
            ADE: Adeh_2070
            ACP: A2cp1_1886
            AFW: Anae109_1754
            ANK: AnaeK_1807
            MXA: MXAN_1283
            SCL: sce3735(leuB1) sce8151(leuB3)
            HOH: Hoch_6339
            SAT: SYN_00088
            SFU: Sfum_2989 Sfum_3031
            DBR: Deba_0342
            PUB: SAR11_0250(leuB)
            MLO: mll4399
            MCI: Mesci_0931 Mesci_5396
            MES: Meso_3381
            PLA: Plav_1425
            SME: SMc04405(leuB)
            SMD: Smed_3178
            RHI: NGR_c06160 NGR_c25920 NGR_c33180(leuB)
            ATU: Atu2791(leuB)
            ARA: Arad_4909(leuB)
            AVI: Avi_4359(leuB)
            RET: RHE_CH04093(leuB)
            REC: RHECIAT_CH0004383(leuB)
            RLE: RL4707(leuB)
            RLT: Rleg2_3900
            RLG: Rleg_4224
            BME: BMEII0404
            BMI: BMEA_B0869(leuB)
            BMF: BAB2_0346
            BMB: BruAb2_0342(leuB)
            BMC: BAbS19_II03270
            BMS: BRA0890(leuB)
            BMT: BSUIS_B0882(leuB)
            BOV: BOV_A0834(leuB)
            BCS: BCAN_B0908(leuB)
            BMR: BMI_II884(leuB)
            OAN: Oant_3287
            BJA: bll0414(leuB) bll0504(leuB) bll6321(leuB) blr2741 blr2781
            BRA: BRADO0353(leuB) BRADO2458
            BBT: BBta_0340(leuB) BBta_2804
            RPA: RPA0227(leuB)
            RPB: RPB_0335
            RPC: RPC_0240
            RPD: RPD_0490
            RPE: RPE_0480
            RPT: Rpal_0226
            RPX: Rpdx1_0409
            NWI: Nwi_2795
            NHA: Nham_3595
            OCA: OCAR_4283(leuB)
            XAU: Xaut_2589
            AZC: AZC_0304
            SNO: Snov_1022 Snov_1601 Snov_2745 Snov_4067 Snov_4333
            MEX: Mext_2524
            MEA: Mex_1p2491(leuB)
            MDI: METDI3254(leuB)
            MRD: Mrad2831_2669
            MET: M446_6646
            MPO: Mpop_2452
            MCH: Mchl_2747
            MNO: Mnod_2259 Mnod_7390
            BID: Bind_1182
            MSL: Msil_3510
            HDN: Hden_3323
            RVA: Rvan_3222
            CCR: CC_0193
            CCS: CCNA_00193(leuB)
            CAK: Caul_0213
            CSE: Cseg_3961
            PZU: PHZ_c0104(leuB)
            BSB: Bresu_3086
            AEX: Astex_0707
            SIL: SPO0210(leuB)
            SIT: TM1040_3762
            RSP: RSP_0859(leuB)
            RSH: Rsph17029_2518
            RSQ: Rsph17025_0162
            RSK: RSKD131_2230
            RCP: RCAP_rcc00085(leuB)
            JAN: Jann_0128
            RDE: RD1_0228(leuB) RD1_3789(leuB)
            PDE: Pden_0440
            DSH: Dshi_0081(imdH) Dshi_3393(leuB)
            KVU: EIO_0631
            MMR: Mmar10_0283
            HNE: HNE_0056(leuB)
            HBA: Hbal_2302
            ZMO: ZMO0677
            ZMN: Za10_0589
            NAR: Saro_2662
            SAL: Sala_1085
            SWI: Swit_4494
            SJP: SJA_C1-22380(leuB)
            ELI: ELI_08335
            GOX: GOX0191
            GBE: GbCGDNIH1_1678
            ACR: Acry_1270 Acry_2147
            GDI: GDI_3085(leuB)
            GDJ: Gdia_3282
            APT: APA01_17110
            RRU: Rru_A1191
            RCE: RC1_3962(leuB)
            MAG: amb4069
            AZL: AZL_008900(leuB)
            PBR: PB2503_06292
            APB: SAR116_1739 SAR116_1823
            MGM: Mmc1_1781
            DIN: Selin_2104
            BSU: BSU28270(leuB)
            BSS: BSUW23_13705(leuB)
            BHA: BH3057(leuB)
            BAN: BA_1421(leuB)
            BAR: GBAA_1421(leuB)
            BAT: BAS1312
            BAH: BAMEG_3174(leuB)
            BAI: BAA_1488(leuB)
            BAL: BACI_c14400(leuB)
            BCE: BC1401
            BCA: BCE_1521(leuB)
            BCZ: BCZK1286(leuB)
            BCR: BCAH187_A1560(leuB)
            BCB: BCB4264_A1454(leuB)
            BCU: BCAH820_1492(leuB)
            BCG: BCG9842_B3890(leuB)
            BCQ: BCQ_1474(leuB)
            BCX: BCA_1456(leuB)
            BCY: Bcer98_1124
            BTK: BT9727_1285(leuB)
            BTL: BALH_1256(leuB)
            BTB: BMB171_C1239(leuB)
            BWE: BcerKBAB4_1323
            BLI: BL00612(leuB)
            BLD: BLi02957(leuB)
            BAY: RBAM_025330(leuB)
            BAO: BAMF_2634(leuB)
            BAE: BATR1942_11905
            BCL: ABC0628 ABC2641(leuB)
            BPU: BPUM_2468(leuB)
            BPF: BpOF4_03005(leuB)
            BMQ: BMQ_1620 BMQ_4696(leuB)
            BMD: BMD_1601 BMD_4682(leuB)
            BSE: Bsel_2532
            BCO: Bcell_1393
            OIH: OB2619(leuB)
            GKA: GK2657
            GTN: GTNG_2586
            GWC: GWCH70_2592
            GYM: GYMC10_5136
            GYC: GYMC61_0860
            GYA: GYMC52_2693
            GCT: GC56T3_0834
            GMC: GY4MC1_0913
            AFL: Aflv_0595(leuB)
            SAU: SA1863(leuB)
            SAV: SAV2058(leuB)
            SAW: SAHV_2043(leuB)
            SAH: SaurJH1_2132
            SAJ: SaurJH9_2095
            SAM: MW1982(leuB)
            SAS: SAS1963
            SAR: SAR2145(leuB)
            SAC: SACOL2047(leuB)
            SAX: USA300HOU_2053(leuB)
            SAA: SAUSA300_2011(leuB)
            SAO: SAOUHSC_02286
            SAE: NWMN_1964(leuB)
            SAD: SAAV_2106(leuB)
            SAB: SAB1943(leuB)
            SEP: SE1659
            SER: SERP1670(leuB)
            SHA: SH0975(leuB)
            SSP: SSP0820
            SCA: Sca_1564(leuB)
            SLG: SLGD_00964
            SSD: SPSINT_1723
            LMO: lmo1988(leuB)
            LMF: LMOf2365_2011(leuB)
            LMH: LMHCC_0572(leuB)
            LMC: Lm4b_02000(leuB)
            LMN: LM5578_2190(leuB)
            LMY: LM5923_2141(leuB)
            LIN: lin2095
            LWE: lwe2007(leuB)
            LSG: lse_1970(leuB)
            LSP: Bsph_3385
            BBE: BBR47_16220(leuB)
            PJD: Pjdr2_1307
            PPY: PPE_01374(leuB)
            PPM: PPSC2_c1476
            AAC: Aaci_2226
            BTS: Btus_0949
            LLA: L0074(leuB)
            LLK: LLKF_1261(leuB)
            LLC: LACR_1320
            SPD: SPD_1115(leuB)
            SPR: spr1135(leuB)
            SPW: SPCG_1046
            SPX: SPG_1149
            SNE: SPN23F_11520(leuB)
            SPV: SPH_1373(leuB)
            SNM: SP70585_1320(leuB)
            SJJ: SPJ_1171(leuB)
            SPP: SPP_1295(leuB)
            SNT: SPT_0971(leuB)
            SNC: HMPREF0837_11244(leuB)
            SNB: SP670_1019(leuB)
            SNP: SPAP_1281
            SMU: SMU.1383(leuB)
            SMC: SmuNN2025_0726(leuB)
            STC: str1202(leuB)
            STL: stu1202(leuB)
            STE: STER_1170
            SSA: SSA_0977(leuB)
            SSU: SSU05_1948
            SSV: SSU98_1953
            SSB: SSUBM407_1810(leuB)
            SSI: SSU1740(leuB)
            SSS: SSUSC84_1762(leuB)
            SGO: SGO_0907(leuB)
            SGA: GALLO_0759(leuB)
            SMB: smi_1217(leuB)
            LFE: LAF_0965
            LME: LEUM_2031
            LCI: LCK_01491(leuB)
            LKI: LKI_07050
            LGS: LEGAS_0262(leuB)
            CAC: CA_C3171(leuB)
            CTH: Cthe_2209
            CDF: CD0992(leuB)
            CDC: CD196_0865(leuB)
            CDL: CDR20291_0845(leuB)
            CBK: CLL_A0324(leuB)
            CBT: CLH_0305(leuB)
            CBE: Cbei_0216
            CKL: CKL_2157(leuB)
            CKR: CKR_1892
            CPY: Cphy_3358
            CCE: Ccel_0128
            CLJ: CLJU_c09080(leuB1) CLJU_c39500(leuB2)
            CSH: Closa_3657
            CCB: Clocel_1322
            CST: CLOST_0417(leuB)
            AMT: Amet_3455
            STH: STH3035
            SWO: Swol_2140
            SLP: Slip_2156
            VPR: Vpar_0097
            AFN: Acfer_0154
            DSY: DSY1371
            DHD: Dhaf_2487
            DRM: Dred_0288
            PTH: PTH_0534(leuB)
            DAU: Daud_1279
            TJR: TherJR_0366
            HMO: HM1_1518(leuB)
            EEL: EUBELI_00761
            ERE: EUBREC_1878
            ELM: ELI_2735
            BPB: bpr_I1336(leuB)
            EHA: Ethha_0925
            RAL: Rumal_1042
            CLO: HMPREF0868_0826(leuB)
            TTE: TTE0019(leuB)
            TEX: Teth514_0017
            TPD: Teth39_0018
            TIT: Thit_0018
            TMT: Tmath_0035
            TBO: Thebr_0018
            CHY: CHY_0524(leuB)
            MTA: Moth_2252
            ADG: Adeg_1962
            CSC: Csac_1333
            ATE: Athe_2099
            COB: COB47_1876
            CHD: Calhy_0656
            COW: Calow_1785
            CKI: Calkr_0485
            CKN: Calkro_0533
            TTM: Tthe_0017
            HOR: Hore_10890
            HAS: Halsa_1420
            AAR: Acear_0211
            MTU: Rv2995c(leuB)
            MTC: MT3073(leuB)
            MRA: MRA_3024(leuB)
            MTF: TBFG_13010
            MTB: TBMG_00975(TBMG_00975.1)
            MBO: Mb3019c(leuB)
            MBB: BCG_3016c(leuB)
            MBT: JTY_3011(leuB)
            MLE: ML1691(leuB)
            MLB: MLBr_01691(leuB)
            MPA: MAP3032c(leuB)
            MAV: MAV_3845(leuB)
            MSM: MSMEG_2379(leuB) MSMEG_3285
            MUL: MUL_1953(leuB)
            MVA: Mvan_2129
            MGI: Mflv_4233
            MAB: MAB_3303c
            MMC: Mmcs_1911 Mmcs_2572
            MKM: Mkms_1957 Mkms_2617
            MJL: Mjls_1891 Mjls_2611
            MSP: Mspyr1_35780
            MMI: MMAR_1716(leuB)
            CGL: NCgl1237(cgl1286)
            CGB: cg1453(leuB)
            CGT: cgR_1364
            CEF: CE1383(leuB)
            CDI: DIP1105(leuB)
            CJK: jk1288(leuB)
            CUR: cur_0764 cur_1141
            CAR: cauri_1136(leuB)
            CKP: ckrop_1234
            CPU: cpfrc_00900(leuB)
            NFA: nfa18790 nfa42200(leuB)
            RHA: RHA1_ro00322(leuB1) RHA1_ro00984(leuB2) RHA1_ro06490(leuB3)
            RER: RER_24010(leuB) RER_33170
            ROP: ROP_07140 ROP_65430(leuB)
            REQ: REQ_25200 REQ_31430(leuB)
            GBR: Gbro_2885 Gbro_3224
            TPR: Tpau_2855
            SRT: Srot_2053
            SCO: SCO5522(leuB)
            SMA: SAV_2718(leuB)
            SGR: SGR_1983
            SCB: SCAB_26951(leuB) SCAB_3581
            LXX: Lxx13130(leuB)
            CMI: CMM_1104(leuB)
            CMS: CMS_1424(leuB)
            ART: Arth_2530
            AAU: AAur_2498(leuB)
            ACH: Achl_2268
            AAI: AARI_14240(leuB)
            RSA: RSal33209_1060
            KRH: KRH_10250(leuB)
            MLU: Mlut_08590
            RMU: RMDY18_07660
            RDN: HMPREF0733_12188(leuB)
            BCV: Bcav_1417
            BFA: Bfae_18770
            JDE: Jden_1704
            XCE: Xcel_2383
            SKE: Sked_10780
            CFL: Cfla_1167
            ICA: Intca_2356
            PAK: HMPREF0675_4418
            PFR: PFREUD_13360(leuB)
            NCA: Noca_3368
            KFL: Kfla_4881
            TFU: Tfu_0615
            NDA: Ndas_0175
            TCU: Tcur_3544
            SRO: Sros_8042
            FRA: Francci3_3632
            FRE: Franean1_1098
            FRI: FraEuI1c_1023
            FAL: FRAAL5843(leuB)
            ACE: Acel_0710
            NML: Namu_1472
            GOB: Gobs_3616 Gobs_4067
            KRA: Krad_1352 Krad_2488
            SEN: SACE_3196(leuB) SACE_6154(leuB)
            SVI: Svir_08950 Svir_14420
            TBI: Tbis_2812
            AMD: AMED_1696(leuB)
            AMI: Amir_6014
            STP: Strop_1239
            SAQ: Sare_1129
            MAU: Micau_1308 Micau_5090
            MIL: ML5_1554 ML5_3221
            CAI: Caci_7787
            SNA: Snas_4289
            MCU: HMPREF0573_11482(leuB)
            BLO: BL1218(leuB)
            BLJ: BLD_0981(leuB)
            BLN: Blon_2070
            BLL: BLJ_0446
            BLB: BBMN68_984(leuB)
            BAD: BAD_1340(leuB)
            BLA: BLA_0567(leuB)
            BLC: Balac_1362
            BLT: Balat_1362
            BDE: BDP_1805(leuB)
            BBI: BBIF_0424(leuB)
            BBP: BBPR_0397(leuB)
            RXY: Rxyl_3130
            CWO: Cwoe_3548
            AFO: Afer_1536
            CCU: Ccur_04390
            ELE: Elen_0585
            OLS: Olsu_1542
            SSM: Spirs_1612 Spirs_3280
            LIL: LA_2152(leuB)
            LIC: LIC11768(leuB)
            LBJ: LBJ_1863(leuB-1)
            LBL: LBL_1421(leuB-1)
            LBI: LEPBI_I2317(leuB)
            LBF: LBF_2251(leuB-1)
            BHY: BHWA1_01041(leuB)
            BRM: Bmur_2222
            BPO: BP951000_0184(leuB)
            ABA: Acid345_2917 Acid345_2964
            ACA: ACP_3470(leuB)
            TSA: AciPR4_1136
            SUS: Acid_4068
            BTH: BT_1857
            BFR: BF3444
            BFS: BF3263(leuB)
            BVU: BVU_2008
            BHL: Bache_3167
            PDI: BDI_2059
            PPN: Palpr_0058
            APS: CFPG_565
            PRU: PRU_0733(leuB)
            SRU: SRU_2148(leuB)
            SRM: SRM_02369(leuB)
            RMR: Rmar_0739
            CHU: CHU_3744(leuB)
            DFE: Dfer_3671
            SLI: Slin_5898
            LBY: Lbys_2677
            MTT: Ftrac_1642
            CPI: Cpin_1985
            PHE: Phep_3428
            GFO: GFO_2098(leuB)
            FJO: Fjoh_1304 Fjoh_2864
            RBI: RB2501_15804
            ZPR: ZPR_1691
            FBC: FB2170_12261 FB2170_13146
            CAO: Celal_3378 Celal_3690
            SMG: SMGWSS_040(leuB)
            SMS: SMDSEM_044(leuB)
            SMH: DMIN_00380
            SUM: SMCARI_048(leuB)
            BBL: BLBBGE_070(leuD)
            BPI: BPLAN_564(leuB)
            FSU: Fisuc_2644
            LBA: Lebu_1710 Lebu_1719
            STR: Sterm_0114
            IPO: Ilyop_1161 Ilyop_2094
            OTE: Oter_3663
            CAA: Caka_0187
            MIN: Minf_1566(leuB)
            AMU: Amuc_0785
            RBA: RB12597(leuB) RB3767(leuB)
            PSL: Psta_2334
            PLM: Plim_3900
            IPA: Isop_0954
            RSD: TGRD_453
            TAI: Taci_1368 Taci_1612
            ACO: Amico_0098
            SYN: slr1517(leuB)
            SYW: SYNW0784(leuB)
            SYC: syc2490_c(leuB)
            SYF: Synpcc7942_1505
            SYD: Syncc9605_1865
            SYE: Syncc9902_0788
            SYG: sync_1712(leuB)
            SYR: SynRCC307_0997(leuB)
            SYX: SynWH7803_1152(leuB)
            SYP: SYNPCC7002_A2354(leuB)
            CYA: CYA_1798(leuB)
            CYB: CYB_1631(leuB)
            TEL: tlr1600(leuB)
            MAR: MAE_00210(leuB)
            CYT: cce_3617(leuB)
            CYP: PCC8801_0340
            CYC: PCC7424_4657
            CYN: Cyan7425_2577
            CYH: Cyan8802_0347
            CYJ: Cyan7822_3255
            GVI: gvip479(leuB)
            ANA: alr1313(leuB)
            NPU: Npun_R2802
            AVA: Ava_2987
            NAZ: Aazo_0972
            PMA: Pro0862(leuB)
            PMM: PMM0786(leuB)
            PMT: PMT0531(leuB)
            PMN: PMN2A_0194
            PMI: PMT9312_0794
            PMB: A9601_08501(leuB)
            PMC: P9515_07951(leuB)
            PMF: P9303_17341(leuB)
            PMG: P9301_08471(leuB)
            PMH: P9215_08811(leuB)
            PMJ: P9211_09751(leuB)
            PME: NATL1_08261(leuB)
            TER: Tery_4403
            AMR: AM1_0898(leuB)
            CTE: CT0615(leuB)
            CPC: Cpar_0631
            CCH: Cag_1901
            CPH: Cpha266_0850
            CPB: Cphamn1_1720
            CLI: Clim_0738
            PVI: Cvib_1173
            PLT: Plut_0603
            PPH: Ppha_2173
            PAA: Paes_0740
            CTS: Ctha_1628
            DET: DET0826(leuB)
            DEH: cbdb_A804(leuB)
            DEB: DehaBAV1_0745
            DEV: DhcVS_730(leuB)
            DEG: DehalGT_0706
            DLY: Dehly_0673
            RRS: RoseRS_1057 RoseRS_1958
            RCA: Rcas_1546 Rcas_3471
            CAU: Caur_0041 Caur_0331
            CAG: Cagg_0588 Cagg_3600
            CHL: Chy400_0047 Chy400_0356
            HAU: Haur_3304 Haur_4439
            TRO: trd_1693(leuB)
            STI: Sthe_0766
            ATM: ANT_03340(leuB) ANT_08240
            DRA: DR_1785
            DGE: Dgeo_1033 Dgeo_1458
            DDR: Deide_12390(leuB)
            DMR: Deima_1515
            TRA: Trad_2208
            TTH: TTC0867
            TTJ: TTHA1230
            TSC: TSC_c07620(leuB)
            MRB: Mrub_1846
            MSV: Mesil_1601
            OPR: Ocepr_0797
            AAE: aq_244(leuB)
            HYA: HY04AAS1_1260
            HTH: HTH_1526(leuB)
            TAL: Thal_0592
            SUL: SYO3AOP1_0648
            SAF: SULAZ_0271(leuB)
            PMX: PERMA_0387(leuB)
            TAM: Theam_0348
            TMA: TM0556
            TPT: Tpet_0364
            TRQ: TRQ2_0381
            TNA: CTN_0112
            TNP: Tnap_0336
            PMO: Pmob_1586
            DTH: DICTH_1066(leuB)
            DTU: Dtur_1193
            TYE: THEYE_A0114
            NDE: NIDE1005(leuB)
            TTR: Tter_0192
            DDF: DEFDS_0681(leuB)
            DAP: Dacet_1506
            CNI: Calni_1247
            MJA: MJ_0720
            MFE: Mefer_1072
            MVU: Metvu_0636
            MFS: MFS40622_1452
            MIF: Metin_0657
            MMP: MMP0539(leuB)
            MMQ: MmarC5_1068
            MMX: MmarC6_0353
            MMZ: MmarC7_1558
            MAE: Maeo_1416
            MVN: Mevan_1693
            MAC: MA0201(leuB) MA3748(leuB)
            MBA: Mbar_A0248 Mbar_A1339
            MMA: MM_1489
            MBU: Mbur_1632
            MMH: Mmah_0129 Mmah_1956
            MEV: Metev_0082 Metev_1314
            MTP: Mthe_0025 Mthe_0855
            MHU: Mhun_1797 Mhun_2363
            MLA: Mlab_0235 Mlab_0609
            MEM: Memar_0637 Memar_1947
            MPI: Mpet_1073 Mpet_2492
            MBN: Mboo_0602 Mboo_2077
            MPL: Mpal_0187 Mpal_2146
            MPD: MCP_1963(aksF) MCP_2993(leuB)
            MTH: MTH1388 MTH184
            MMG: MTBMA_c06370 MTBMA_c17740(leuB)
            MST: Msp_1484(leuB)
            MSI: Msm_0373 Msm_1298
            MRU: mru_0103(leuB) mru_1033(aksF)
            MFV: Mfer_0585 Mfer_1273
            MKA: MK0782(leuB_1) MK1215(leuB_2)
            AFU: AF0628(leuB)
            APO: Arcpr_0379
            FPL: Ferp_2126
            HMA: rrnAC0340(ipmD)
            HWA: HQ2707A(leuB)
            NPH: NP2190A(leuB)
            HLA: Hlac_0870
            HUT: Huta_0651
            HMU: Hmuk_2659
            HTU: Htur_2762
            NMG: Nmag_0898
            HVO: HVO_1502(leuB)
            HJE: HacjB3_10520
            HBO: Hbor_17360
            PTO: PTO0910
            PHO: PH1722
            PAB: PAB0289(leuB-2) PAB2424(leuB-1)
            PFU: PF0940
            TKO: TK0280
            ABI: Aboo_0166
            RCI: RCIX2644(leuB-2) RCIX993(leuB-1)
            IHO: Igni_0982
            IAG: Igag_1566
            SSO: SSO0723(leuB)
            STO: ST0433
            SAI: Saci_0600(leuB)
            SIS: LS215_1512
            SIA: M1425_1417
            SIM: M1627_1467
            SID: M164_1411
            SIY: YG5714_1412
            SIN: YN1551_1431
            SII: LD85_1622
            MSE: Msed_0088
            PAI: PAE1995
            PIS: Pisl_1815
            PCL: Pcal_1605
            PAS: Pars_2064
            CMA: Cmaq_1172
            TNE: Tneu_0833
            VDI: Vdis_0683
            NMR: Nmar_1069
            CSY: CENSYa_0612
            KCR: Kcr_0190
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.85
            IUBMB Enzyme Nomenclature: 1.1.1.85
            ExPASy - ENZYME nomenclature database: 1.1.1.85
            BRENDA, the Enzyme Database: 1.1.1.85
            CAS: 9030-97-1
///
ENTRY       EC 1.1.1.86                 Enzyme
NAME        ketol-acid reductoisomerase;
            dihydroxyisovalerate dehydrogenase (isomerizing);
            acetohydroxy acid isomeroreductase;
            ketol acid reductoisomerase;
            alpha-keto-beta-hydroxylacyl reductoisomerase;
            2-hydroxy-3-keto acid reductoisomerase;
            acetohydroxy acid reductoisomerase;
            acetolactate reductoisomerase;
            dihydroxyisovalerate (isomerizing) dehydrogenase;
            isomeroreductase;
            reductoisomerase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase
            (isomerizing)
REACTION    (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ =
            (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+ [RN:R04439]
ALL_REAC    R04439;
            (other) R03051 R04440 R05068 R05069 R05071
SUBSTRATE   (R)-2,3-dihydroxy-3-methylbutanoate [CPD:C04272];
            NADP+ [CPD:C00006]
PRODUCT     (S)-2-hydroxy-2-methyl-3-oxobutanoate [CPD:C06010];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also catalyses the reduction of 2-aceto-2-hydroxybutanoate to
            2,3-dihydroxy-3-methylpentanoate.
REFERENCE   1  [PMID:4388025]
  AUTHORS   Arfin SM, Umbarger HE.
  TITLE     Purification and properties of the acetohydroxy acid
            isomeroreductase of Salmonella typhimurium.
  JOURNAL   J. Biol. Chem. 244 (1969) 1118-27.
  ORGANISM  Salmonella typhimurium
REFERENCE   2
  AUTHORS   Hill, R.K., Sawada, S. and Arfin, S.M.
  TITLE     Stereochemistry of valine and isoleucine biosynthesis. IV.
            Synthesis, configuration, and enzymatic specificity of
            alpha-acetolactate and alpha-aceto-alpha-hydroxybutyrate.
  JOURNAL   Bioorg. Chem. 8 (1979) 175-189.
REFERENCE   3
  AUTHORS   Kiritani, K., Narise, S. and Wagner, R.P.
  TITLE     The reductoisomerase of Neurospora crassa.
  JOURNAL   J. Biol. Chem. 241 (1966) 2047-2051.
REFERENCE   4  [PMID:5866387]
  AUTHORS   Satyanarayana T, Radhakrishnan AN.
  TITLE     Biosynthesis of valine and isoleucine in plants. 3. Reductoisomerase
            of Phaseolus radiatus.
  JOURNAL   Biochim. Biophys. Acta. 110 (1965) 380-8.
  ORGANISM  Phaseolus radiatus
PATHWAY     ec00290  Valine, leucine and isoleucine biosynthesis
            ec00770  Pantothenate and CoA biosynthesis
            ec01100  Metabolic pathways
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00053  ketol-acid reductoisomerase
GENES       ATH: AT3G58610
            POP: POPTR_817858 POPTR_827835
            RCU: RCOM_0553440 RCOM_1014850
            VVI: 100262542
            OSA: 4325375 4339677
            SBI: SORBI_03g029720 SORBI_09g029170
            ZMA: 100191801 100193695 100382989
            PPP: PHYPADRAFT_110501 PHYPADRAFT_145519
            CRE: CHLREDRAFT_140839(AAI1)
            VCN: VOLCADRAFT_74529
            OLU: OSTLU_30575
            OTA: Ot03g02490
            CME: CMR121C
            SCE: YLR355C(ILV5)
            AGO: AGOS_ACL198W
            KLA: KLLA0A02673g
            LTH: KLTH0G17292g
            PPA: PAS_chr1-1_0432
            VPO: Kpol_543p30
            ZRO: ZYRO0B08118g
            CGR: CAGL0B03047g
            DHA: DEHA2F09570g
            PIC: PICST_78299(ILV5)
            PGU: PGUG_01529
            LEL: LELG_04680
            CAL: CaO19.7733(ILV5)
            CTP: CTRG_02949
            CDU: CD36_60880
            YLI: YALI0D03135g
            CLU: CLUG_01479
            NCR: NCU03608
            PAN: PODANSg7891
            MGR: MGG_01808(MG01808.4)
            FGR: FG10118.1
            SSL: SS1G_03855
            BFU: BC1G_04443
            ANI: AN2526.2
            AFM: AFUA_3G14490
            NFI: NFIA_062770
            AOR: AO090701000557
            ANG: An09g03940
            AFV: AFLA_060300
            ACT: ACLA_041940
            PCS: Pc13g15810
            CIM: CIMG_05641
            CPW: CPC735_067570
            URE: UREG_06109
            PNO: SNOG_06575
            TML: GSTUM_00011835001
            SPO: SPBC56F2.12(ilv5)
            CNE: CNF02480
            CNB: CNBF2210
            LBC: LACBIDRAFT_190413
            MPR: MPER_08942
            CCI: CC1G_06305
            SCM: SCHCODRAFT_82317
            UMA: UM04741.1
            MGL: MGL_3299
            PTI: PHATRDRAFT_30967
            TPS: THAPSDRAFT_23228
            PIF: PITG_02925
            ECO: b3774(ilvC)
            ECJ: JW3747(ilvC)
            ECD: ECDH10B_3963(ilvC)
            EBW: BWG_3459(ilvC)
            ECE: Z5285(ilvC)
            ECS: ECs4708
            ECF: ECH74115_5208(ilvC)
            ETW: ECSP_4823(ilvC)
            EOJ: ECO26_4812(ilvC)
            EOI: ECO111_4600(ilvC)
            EOH: ECO103_4390(ilvC)
            ECG: E2348C_4076(ilvC)
            EOK: G2583_4568(ilvC)
            ECC: c4696(ilvC)
            ECP: ECP_3967
            ECI: UTI89_C4330(ilvC)
            ECV: APECO1_2697(ilvC)
            ECX: EcHS_A3990(ilvC)
            ECW: EcE24377A_4285(ilvC)
            ECM: EcSMS35_4140(ilvC)
            ECY: ECSE_4057
            ECR: ECIAI1_3961(ilvC)
            ECQ: ECED1_4460(ilvC)
            ECK: EC55989_4246(ilvC)
            ECT: ECIAI39_3012(ilvC)
            EUM: ECUMN_4300(ilvC)
            ECZ: ECS88_4197(ilvC)
            ECL: EcolC_4228
            EBR: ECB_03652(ilvC)
            EBD: ECBD_4265
            EFE: EFER_3728(ilvC)
            STY: STY3648(ilvC)
            STT: t3389(ilvC)
            STM: STM3909(ilvC)
            SPT: SPA3748(ilvC)
            SEK: SSPA3493
            SPQ: SPAB_04854
            SEI: SPC_4022(ilvC)
            SEC: SC3814(ilvC)
            SEH: SeHA_C4240
            SEE: SNSL254_A4191
            SEW: SeSA_A4119
            SEA: SeAg_B4134
            SED: SeD_A4299
            SEG: SG3533(ilvC)
            SET: SEN3715(ilvC)
            SES: SARI_03745
            YPE: YPO3888(ilvC)
            YPK: y0345(ilvC)
            YPA: YPA_0132
            YPN: YPN_0077
            YPM: YP_3158(ilvC)
            YPP: YPDSF_3501
            YPG: YpAngola_A0493(ilvC)
            YPZ: YPZ3_3434(ilvC)
            YPS: YPTB0145(ilvC)
            YPI: YpsIP31758_0163(ilvC)
            YPY: YPK_4051
            YPB: YPTS_0154
            YEN: YE0155(ilvC)
            SFL: SF3848(ilvC)
            SFX: S3910(ilvC)
            SFV: SFV_3729(ilvC)
            SSN: SSON_3945(ilvC)
            SBO: SBO_3785(ilvC)
            SBC: SbBS512_E4146(ilvC)
            SDY: SDY_3974(ilvC)
            ECA: ECA4221(ilvC)
            PCT: PC1_4021
            PWA: Pecwa_4213
            ETA: ETA_01900(ilvC)
            EPY: EpC_01760(ilvC)
            EAM: EAMY_0164(ilvC)
            EAY: EAM_0157(ilvC)
            EBI: EbC_01890(ilvC)
            PLU: plu4668(ilvC)
            PAY: PAU_04148(ilvC)
            BUC: BU599(ilvC)
            BAS: BUsg575(ilvC)
            BAB: bbp541(ilvC)
            BCC: BCc_388(ilvC)
            BAP: BUAP5A_591(ilvC)
            BAU: BUAPTUC7_592(ilvC)
            SGL: SG2391
            ENT: Ent638_4009
            ENC: ECL_05008
            ESC: Entcl_4255
            ESA: ESA_03781
            CTU: Ctu_02130(ilvC)
            KPN: KPN_04273(ilvC)
            KPE: KPK_5407(ilvC)
            KPU: KP1_0135(ilvC)
            KVA: Kvar_4955
            CKO: CKO_00113
            CRO: ROD_39741(ilvC)
            SPE: Spro_4751
            PMR: PMI3305(ilvC)
            EIC: NT01EI_0083
            ETR: ETAE_0094(ilvC)
            BFL: Bfl588(ilvC)
            BPN: BPEN_609(ilvC)
            BVA: BVAF_590(ilvC)
            DDA: Dd703_3768
            DDC: Dd586_3910
            DDD: Dda3937_00256(ilvC)
            DZE: Dd1591_0146
            XBO: XBJ1_4189(ilvC)
            XNE: XNC1_0376(ilvC)
            PAM: PANA_3823(ilvC)
            PVA: Pvag_3105(ilvC)
            PAO: Pat9b_3834
            HIN: HI0682(ilvC)
            HIT: NTHI0804(ilvC)
            HIP: CGSHiEE_08680
            HIQ: CGSHiGG_06705
            HIF: HIBPF17020
            HIL: HICON_08060
            HAP: HAPS_1327(ilvC)
            HSO: HS_1671(ilvC)
            HSM: HSM_1833
            PMU: PM1284(ilvC)
            MSU: MS0045(ilvC)
            APL: APL_1853(ilvC)
            APJ: APJL_1897(ilvC)
            APA: APP7_1943
            ASU: Asuc_0563
            AAP: NT05HA_2297
            AAT: D11S_0224
            XFA: XF1822
            XFT: PD1043(ilvC)
            XFM: Xfasm12_1201
            XFN: XfasM23_1107
            XCC: XCC3323(ilvC)
            XCB: XC_0841
            XCA: xccb100_0874(ilvC)
            XCV: XCV3579(ilvC)
            XAC: XAC3451(ilvC)
            XOO: XOO0946(ilvC)
            XOM: XOO_0865
            XOP: PXO_02605(ilvC)
            XAL: XALc_0759(ilvC)
            SML: Smlt3913
            SMT: Smal_3328
            PSU: Psesu_0445
            VCH: VC0162
            VCO: VC0395_A2550(ilvC)
            VCM: VCM66_0161(ilvC)
            VCJ: VCD_001447
            VVU: VV1_1077
            VVY: VV0035
            VVM: VVM_00108
            VPA: VP0035
            VHA: VIBHAR_00478
            VSP: VS_0061
            VEX: VEA_001983
            VFI: VF_2528(ilvC)
            VFM: VFMJ11_2657
            VSA: VSAL_I0087(ilvC)
            PPR: PBPRA0085
            PAE: PA4694(ilvC)
            PAU: PA14_62130(ilvC)
            PAP: PSPA7_5408(ilvC)
            PAG: PLES_50791(ilvC)
            PPU: PP_4678(ilvC)
            PPF: Pput_4542
            PPG: PputGB1_4676
            PPW: PputW619_0756
            PST: PSPTO_0983(ilvC)
            PSB: Psyr_0848
            PSP: PSPPH_0874(ilvC)
            PFL: PFL_5253(ilvC)
            PFO: Pfl01_4786
            PFS: PFLU5218
            PEN: PSEEN4709(ilvC)
            PMY: Pmen_1009
            PSA: PST_3256(ilvC)
            CJA: CJA_0668(ilvC)
            AVN: Avin_42500(ilvC)
            PAR: Psyc_0529(ilvC)
            PCR: Pcryo_0524
            PRW: PsycPRwf_0611
            ACI: ACIAD3102(ilvC)
            ACD: AOLE_16710
            ACB: A1S_0545
            ABM: ABSDF2975(ilvC)
            ABY: ABAYE3238(ilvC)
            ABC: ACICU_00553
            ABN: AB57_0626(ilvC)
            ABB: ABBFA_003011(ilvC)
            MCT: MCR_1546(ilvC)
            SON: SO_4349(ilvC)
            SDN: Sden_3415
            SFR: Sfri_0421
            SAZ: Sama_3282
            SBL: Sbal_4032
            SBM: Shew185_4010
            SBN: Sbal195_4129
            SBP: Sbal223_3935
            SLO: Shew_0288
            SPC: Sputcn32_3615
            SSE: Ssed_4166
            SPL: Spea_0344
            SHE: Shewmr4_0361
            SHM: Shewmr7_3665
            SHN: Shewana3_0355
            SHW: Sputw3181_3755
            SHL: Shal_3945
            SWD: Swoo_0441
            SWP: swp_0358
            SVO: SVI_3870(ilvC)
            CPS: CPS_4839(ilvC)
            PHA: PSHAa0849(ilvC)
            PAT: Patl_4255
            PSM: PSM_A2198(ilvC)
            SDE: Sde_2539
            MAQ: Maqu_0884
            AMC: MADE_04021
            PIN: Ping_0853
            TTU: TERTU_1066(ilvC)
            FBL: Fbal_3651
            MCA: MCA2272(ilvC)
            FTW: FTW_1086(ilvC)
            FTL: FTL_0916
            FTH: FTH_0896(ilvC)
            FTA: FTA_0966(ilvC)
            FTN: FTN_1040(ilvC)
            FPH: Fphi_1550
            TCX: Tcr_0636
            NOC: Noc_2518
            NHL: Nhal_0657
            NWA: Nwat_0616
            ALV: Alvin_0950
            AEH: Mlg_0544
            HHA: Hhal_0693
            TGR: Tgr7_2156
            TKM: TK90_1780
            HNA: Hneap_1900
            HCH: HCH_05914(ilvC)
            CSA: Csal_0504
            HEL: HELO_1337(ilvC)
            ABO: ABO_0485(ilvC)
            MMW: Mmwyl1_3846
            AHA: AHA_0153(ilvC)
            ASA: ASA_4236(ilvC)
            TAU: Tola_0279
            AFE: Lferr_0894
            AFR: AFE_0747(ilvC)
            CRP: CRP_125
            RMA: Rmag_0447
            VOK: COSY_0413(ilvC)
            GPB: HDN1F_03470(ilvC)
            NMA: NMA1763(ilvC)
            NME: NMB1574(ilvC)
            NMC: NMC1494(ilvC)
            NMN: NMCC_1477(ilvC)
            NMI: NMO_1385(ilvC)
            NGO: NGO1233
            NGK: NGK_0276
            NLA: NLA_7090(ilvC)
            CVI: CV_0588(ilvC)
            LHK: LHK_00158(ilvC)
            RSO: RSc2075(ilvC)
            RSC: RCFBP_11314(ilvC)
            RSL: RPSI07_1353(ilvC)
            RPI: Rpic_2226
            RPF: Rpic12D_1903
            REU: Reut_A0949
            REH: H16_A1037(ilvC)
            RME: Rmet_0913
            CTI: RALTA_A1021(ilvC)
            BMA: BMA1846(ilvC) BMAA1453
            BMV: BMASAVP1_A1115(ilvC)
            BML: BMA10229_2160 BMA10229_A0751(ilvC)
            BMN: BMA10247_0398(ilvC) BMA10247_A0844
            BPS: BPSL1198(ilvC) BPSS0305
            BPM: BURPS1710b_1421(ilvC) BURPS1710b_A1855(ilvC)
            BPL: BURPS1106A_1283(ilvC) BURPS1106A_A0433(ilvC)
            BPD: BURPS668_1276(ilvC) BURPS668_A0529(ilvC)
            BPR: GBP346_A1299(ilvC_1)
            BTE: BTH_I1047(ilvC-1) BTH_II2094(ilvC-2)
            BVI: Bcep1808_2347
            BUR: Bcep18194_A5590
            BCN: Bcen_1652
            BCH: Bcen2424_2263
            BCM: Bcenmc03_2286
            BCJ: BCAL2357(ilvC)
            BAM: Bamb_2301
            BAC: BamMC406_2179
            BMU: Bmul_1015
            BMJ: BMULJ_02249(ilvC)
            BXE: Bxe_A3229
            BPH: Bphy_2020
            BPY: Bphyt_1330
            BGL: bglu_1g26060
            BGE: BC1002_0943
            BRH: RBRH_02511
            PNU: Pnuc_1061
            PNE: Pnec_0812
            BPE: BP0791(ilvC)
            BPA: BPP3435(ilvC)
            BBR: BB3885(ilvC)
            BPT: Bpet1606(ilvC)
            BAV: BAV2671(ilvC)
            AXY: AXYL_01240(ilvC)
            TEQ: TEQUI_0193
            RFR: Rfer_3324
            POL: Bpro_2319
            PNA: Pnap_1719
            AAV: Aave_3110
            AJS: Ajs_1771
            DIA: Dtpsy_1951
            VEI: Veis_1747
            DAC: Daci_4865
            VAP: Vapar_2371
            VPE: Varpa_2554
            CTT: CtCNB1_1660
            ADN: Alide_1763
            MPT: Mpe_A2103
            HAR: HEAR1239(ilvC)
            MMS: mma_2148(ilvC)
            HSE: Hsero_1737(ilvC) Hsero_3806(ilvC)
            LCH: Lcho_2891
            TIN: Tint_2152
            NEU: NE1323(ilvC)
            NET: Neut_1260
            NMU: Nmul_A0472
            EBA: ebA7134(ilvC)
            AZO: azo3156(ilvC)
            DAR: Daro_3073
            TMZ: Tmz1t_2775
            TBD: Tbd_1989
            MFA: Mfla_2121
            MMB: Mmol_0616
            MEH: M301_0629
            MEI: Msip34_0607
            MEP: MPQ_0633(ilvC)
            APP: CAP2UW1_4118
            SLT: Slit_2402
            GCA: Galf_2516
            HPY: HP0330
            HPJ: jhp0313(ilvC)
            HPA: HPAG1_0334
            HPS: HPSH_01715
            HPG: HPG27_312
            HPP: HPP12_1582(ilvC)
            HPB: HELPY_0334(ilvC)
            HPL: HPB8_1234(ilvC)
            HPC: HPPC_01675
            HPM: HPSJM_01770
            HHE: HH1204(ilvC)
            HAC: Hac_0990(ilvC)
            HMS: HMU11790(ilvC)
            HFE: Hfelis_10840(ilvC)
            WSU: WS1878(ilvC)
            TDN: Suden_0541
            SKU: Sulku_0583
            CJE: Cj0632(ilvC)
            CJR: CJE0735(ilvC)
            CJJ: CJJ81176_0660(ilvC)
            CJU: C8J_0591(ilvC)
            CJN: ICDCCJ_578
            CJD: JJD26997_1367(ilvC)
            CFF: CFF8240_1127(ilvC)
            CCV: CCV52592_1581(ilvC)
            CHA: CHAB381_0374(ilvC)
            CCO: CCC13826_2003(ilvC)
            CLA: Cla_0948(ilvC)
            ABU: Abu_0237(ilvC)
            ANT: Arnit_2836
            SDL: Sdel_0867
            NIS: NIS_1161(ilvC)
            SUN: SUN_0443
            NSA: Nitsa_0379
            NAM: NAMH_1150(ilvC)
            GSU: GSU1909(ilvC)
            GME: Gmet_1262
            GUR: Gura_3718
            GLO: Glov_2501
            GBM: Gbem_2758(ilvC)
            GEO: Geob_1507
            GEM: GM21_1483
            PCA: Pcar_2518(ilvC)
            PPD: Ppro_2555
            DVU: DVU1378(ilvC)
            DVL: Dvul_1690
            DVM: DvMF_0155
            DDE: Dde_2166
            DDS: Ddes_1905
            DMA: DMR_21850(ilvC)
            DSA: Desal_2396
            DAS: Daes_1773
            DBA: Dbac_0410
            DRT: Dret_1660
            DPS: DP0726 DP0727
            DAK: DaAHT2_1105
            DPR: Despr_3279
            DOL: Dole_2039
            DAL: Dalk_0563
            DAT: HRM2_21070(ilvC)
            ADE: Adeh_1976
            ACP: A2cp1_1987
            AFW: Anae109_1879
            ANK: AnaeK_1902
            SCL: sce3732(ilvC)
            SAT: SYN_01709
            SFU: Sfum_2984 Sfum_3026
            DBR: Deba_0338
            AMA: AM1310(ilvC)
            AMF: AMF_990(ilvC)
            ACN: ACIS_00096(ilvC)
            PUB: SAR11_0001(ilvC)
            MLO: mll1405
            MCI: Mesci_3259
            MES: Meso_1496
            PLA: Plav_2466
            SME: SMc04346(ilvC)
            SMD: Smed_1962
            RHI: NGR_c19760(ilvC)
            ATU: Atu2019(ilvC)
            ARA: Arad_2866(ilvC)
            AVI: Avi_2778(ilvC)
            RET: RHE_CH02744(ilvC)
            REC: RHECIAT_CH0002884(ilvC)
            RLE: RL3205(ilvC)
            RLT: Rleg2_2492
            RLG: Rleg_2749
            BME: BMEI0624
            BMI: BMEA_A1427(ilvC)
            BMF: BAB1_1399
            BMB: BruAb1_1376(ilvC)
            BMC: BAbS19_I13070
            BMS: BR1380(ilvC)
            BMT: BSUIS_A1431(ilvC)
            BOV: BOV_1337(ilvC)
            BCS: BCAN_A1411(ilvC)
            BMR: BMI_I1390(ilvC)
            OAN: Oant_1813
            BJA: bll6497(ilvC)
            BRA: BRADO5559(ilvC)
            BBT: BBta_6082(ilvC)
            RPA: RPA2035(ilvC)
            RPB: RPB_3341
            RPC: RPC_3248
            RPD: RPD_2102
            RPE: RPE_2195
            RPT: Rpal_2246
            RPX: Rpdx1_3477
            NWI: Nwi_2341
            NHA: Nham_2720
            OCA: OCAR_5292(ilvC)
            BHE: BH10890(ilvC)
            BQU: BQ08540(ilvC)
            BBK: BARBAKC583_0917(ilvC)
            BTR: Btr_1549(ilvC)
            BGR: Bgr_13600(ilvC)
            BCD: BARCL_0581(ilvC)
            XAU: Xaut_1490
            AZC: AZC_2374
            SNO: Snov_0330
            MEX: Mext_0285
            MEA: Mex_1p0175(ilvC)
            MDI: METDI0158(ilvC)
            MRD: Mrad2831_5327
            MET: M446_3416
            MPO: Mpop_0361
            MCH: Mchl_0329
            MNO: Mnod_2857
            BID: Bind_2418
            MSL: Msil_3011
            HDN: Hden_2076
            RVA: Rvan_2284
            CCR: CC_2120
            CCS: CCNA_02204
            CAK: Caul_3381
            CSE: Cseg_1300
            PZU: PHZ_c0777(ilvC)
            BSB: Bresu_3092
            AEX: Astex_0714
            SIL: SPO1366(ilvC)
            SIT: TM1040_2303
            RSP: RSP_1865
            RSH: Rsph17029_0514
            RSQ: Rsph17025_0651
            RSK: RSKD131_0175
            RCP: RCAP_rcc01214(ilvC)
            JAN: Jann_1238
            RDE: RD1_1954(ilvC)
            PDE: Pden_1760
            DSH: Dshi_2396(ilvC)
            KVU: EIO_0997
            MMR: Mmar10_0290 Mmar10_2020
            HNE: HNE_0447(ilvC)
            HBA: Hbal_0470
            ZMO: ZMO1141
            ZMN: Za10_0185
            NAR: Saro_2263
            SAL: Sala_1472
            SWI: Swit_0611
            SJP: SJA_C1-14610(ilvC)
            ELI: ELI_05505
            GOX: GOX1089
            GBE: GbCGDNIH1_1478
            ACR: Acry_2559
            GDI: GDI_0024(ilvC)
            GDJ: Gdia_1781
            APT: APA01_19250
            RRU: Rru_A0469
            RCE: RC1_1973(ilvC)
            MAG: amb3509
            AZL: AZL_021700(ilvC)
            PBR: PB2503_06327
            APB: SAR116_0711
            MGM: Mmc1_0900
            DIN: Selin_0695
            BSU: BSU28290(ilvC)
            BSS: BSUW23_13715(ilvC)
            BHA: BH3059(ilvC)
            BAN: BA_1419(ilvC-1) BA_1852(ilvC-2)
            BAR: GBAA_1419(ilvC-1) GBAA_1852(ilvC-2)
            BAT: BAS1310 BAS1716
            BAH: BAMEG_2740(ilvC2) BAMEG_3176(ilvC1)
            BAI: BAA_1486(ilvC1) BAA_1921(ilvC2)
            BAL: BACI_c14380(ilvC1) BACI_c18380(ilvC2)
            BCE: BC1399 BC1779
            BCA: BCE_1519(ilvC) BCE_1936(ilvC)
            BCZ: BCZK1284(ilvC) BCZK1668(ilvC)
            BCR: BCAH187_A1558(ilvC1) BCAH187_A1968(ilvC2)
            BCB: BCB4264_A1452(ilvC1) BCB4264_A1853(ilvC2)
            BCU: BCAH820_1490(ilvC1) BCAH820_1890(ilvC2)
            BCG: BCG9842_B3489(ilvC2) BCG9842_B3892(ilvC1)
            BCQ: BCQ_1472(ilvC) BCQ_1853(ilvC)
            BCX: BCA_1454(ilvC1) BCA_1858(ilvC2)
            BCY: Bcer98_1122
            BTK: BT9727_1283(ilvC) BT9727_1693(ilvC)
            BTL: BALH_1254 BALH_1626
            BTB: BMB171_C1237(ilvC1) BMB171_C1645(ilvC2)
            BWE: BcerKBAB4_1321 BcerKBAB4_1709
            BLI: BL00610(ilvC)
            BLD: BLi02959(ilvC)
            BAY: RBAM_025350(ilvC)
            BAO: BAMF_2636(ilvC)
            BAE: BATR1942_11915
            BCL: ABC2643(ilvC)
            BPU: BPUM_2470(ilvC)
            BPF: BpOF4_03015(ilvC)
            BMQ: BMQ_4698(ilvC)
            BMD: BMD_4684(ilvC)
            BSE: Bsel_2530
            BCO: Bcell_1395
            OIH: OB2621(ilvC)
            GKA: GK2659
            GTN: GTNG_2588
            GWC: GWCH70_2594
            GYM: GYMC10_5140
            GYC: GYMC61_0858
            GYA: GYMC52_2695
            GCT: GC56T3_0832
            GMC: GY4MC1_0911
            AFL: Aflv_0593(ilvC)
            SAU: SA1861(ilvC)
            SAV: SAV2056(ilvC)
            SAW: SAHV_2041(ilvC)
            SAH: SaurJH1_2130
            SAJ: SaurJH9_2093
            SAM: MW1980(ilvC)
            SAS: SAS1961
            SAR: SAR2143(ilvC)
            SAC: SACOL2045(ilvC)
            SAX: USA300HOU_2051(ilvC)
            SAA: SAUSA300_2009(ilvC)
            SAO: SAOUHSC_02284
            SAE: NWMN_1962(ilvC)
            SAD: SAAV_2104(ilvC)
            SAB: SAB1941(ilvC)
            SEP: SE1657
            SER: SERP1668(ilvC)
            SHA: SH0977(ilvC)
            SSP: SSP0822
            SCA: Sca_1562(ilvC)
            SLG: SLGD_00966
            SSD: SPSINT_1721
            LMO: lmo1986(ilvC)
            LMF: LMOf2365_2009(ilvC)
            LMH: LMHCC_0574(ilvC)
            LMC: Lm4b_01998(ilvC)
            LMN: LM5578_2188(ilvC)
            LMY: LM5923_2139(ilvC)
            LIN: lin2093
            LWE: lwe2005(ilvC)
            LSG: lse_1968(ilvC)
            LSP: Bsph_3387
            MCL: MCCL_0858(ilvC)
            BBE: BBR47_16200(ilvC)
            PJD: Pjdr2_1304
            PPY: PPE_01372(ilvC)
            PPM: PPSC2_c1474
            AAC: Aaci_2227
            BTS: Btus_0947
            LLA: L0080(ilvC)
            LLK: LLKF_1269(ilvC)
            LLC: LACR_1309
            LLM: llmg_1277(ilvC)
            SPN: SP_0447
            SPD: SPD_0406(ilvC)
            SPR: spr0403(ilvC)
            SPW: SPCG_0441(ilvC)
            SPX: SPG_0409
            SNE: SPN23F_04190(ilvC)
            SPV: SPH_0553(ilvC)
            SNM: SP70585_0516(ilvC)
            SJJ: SPJ_0430(ilvC)
            SPP: SPP_0477(ilvC)
            SNT: SPT_0483(ilvC)
            SNC: HMPREF0837_10739(ilvC)
            SNB: SP670_0521(ilvC)
            SNP: SPAP_0461
            SMU: SMU.233(ilvC)
            SMC: SmuNN2025_1723(ilvC)
            STC: str1871(ilvC)
            STL: stu1871(ilvC)
            STE: STER_1848
            SSA: SSA_1968(ilvC)
            SSU: SSU05_1886
            SSV: SSU98_1889
            SSB: SSUBM407_1752(ilvC)
            SSI: SSU1680(ilvC)
            SSS: SSUSC84_1704(ilvC)
            SGO: SGO_0528(ilvC)
            SGA: GALLO_0307(ilvC)
            SMB: smi_1823(ilvC)
            LME: LEUM_1957
            CAC: CA_C0091(ilvC)
            CNO: NT01CX_2028(ilvC)
            CTH: Cthe_2518
            CDF: CD1565(ilvC)
            CDC: CD196_1436(ilvC)
            CDL: CDR20291_1413(ilvC)
            CBK: CLL_A0327(ilvC)
            CBT: CLH_0308(ilvC)
            CBE: Cbei_0218
            CKL: CKL_1080(ilvC1) CKL_1089(ilvC2)
            CKR: CKR_0983 CKR_0991
            CPY: Cphy_3020
            CCE: Ccel_3435
            CLJ: CLJU_c20390(ilvC2)
            CSH: Closa_2206
            CCB: Clocel_1325
            CST: CLOST_1421(ilvC)
            AMT: Amet_3402
            STH: STH2688
            SWO: Swol_2144
            SLP: Slip_2160
            VPR: Vpar_1436
            AFN: Acfer_0158
            DSY: DSY1368
            DHD: Dhaf_2484
            DRM: Dred_0283
            DAE: Dtox_0593
            PTH: PTH_0529(ilvC)
            DAU: Daud_0354
            TJR: TherJR_0362
            HMO: HM1_1513(ilvC)
            EEL: EUBELI_01373
            ERE: EUBREC_2000
            ELM: ELI_2739
            BPB: bpr_I1657(ilvC)
            EHA: Ethha_0183
            RAL: Rumal_0497
            TMR: Tmar_1772
            TTE: TTE0015(ilvC)
            TEX: Teth514_0013
            TPD: Teth39_0014
            TIT: Thit_0014
            TMT: Tmath_0031
            TBO: Thebr_0014
            CHY: CHY_0519(ilvC)
            MTA: Moth_1350
            ADG: Adeg_0225
            CSC: Csac_1144
            ATE: Athe_0504
            COB: COB47_0454
            CHD: Calhy_2166
            COW: Calow_0358
            CKI: Calkr_1819
            CKN: Calkro_2143
            TTM: Tthe_0013
            HOR: Hore_10850
            HAS: Halsa_1424
            AAR: Acear_0207
            MTU: Rv3001c(ilvC)
            MTC: MT3081(ilvC)
            MRA: MRA_3031(ilvC)
            MTF: TBFG_13016
            MTB: TBMG_00969(TBMG_00969.1)
            MBO: Mb3026c(ilvC)
            MBB: BCG_3023c(ilvC)
            MBT: JTY_3018(ilvC)
            MLE: ML1694(ilvC)
            MLB: MLBr_01694(ilvC)
            MPA: MAP3036c(ilvC)
            MAV: MAV_3850(ilvC)
            MSM: MSMEG_2374(ilvC)
            MUL: MUL_1949(ilvC)
            MVA: Mvan_2124
            MGI: Mflv_4237
            MAB: MAB_3321c
            MMC: Mmcs_1908
            MKM: Mkms_1954
            MJL: Mjls_1888
            MSP: Mspyr1_35820
            MMI: MMAR_1712(ilvC)
            CGL: NCgl1224(cgl1273)
            CGB: cg1437(ilvC)
            CGT: cgR_1349
            CEF: CE1367(ilvC)
            CDI: DIP1100(ilvC)
            CJK: jk1298(ilvC)
            CUR: cur_0755
            CAR: cauri_1132(ilvC)
            CKP: ckrop_1237
            CPU: cpfrc_00894(ilvC)
            NFA: nfa42300(ilvC)
            RHA: RHA1_ro06488(ilvC)
            RER: RER_23990(ilvC)
            ROP: ROP_65410(ilvC)
            REQ: REQ_31460(ilvC)
            GBR: Gbro_3228
            TPR: Tpau_2862
            SRT: Srot_2013
            SCO: SCO5514(ilvC) SCO7154(ilvC2)
            SMA: SAV_2731(ilvC)
            SGR: SGR_1998
            SCB: SCAB_27061(ilvC)
            TWH: TWT207(ilvC)
            TWS: TW565(ilvC)
            LXX: Lxx13170(ilvC)
            CMI: CMM_1096(ilvC)
            CMS: CMS_1416(ilvC)
            ART: Arth_2537
            AAU: AAur_2507(ilvC)
            ACH: Achl_2277
            AAI: AARI_13810(ilvC)
            RSA: RSal33209_1045
            KRH: KRH_10230(ilvC)
            MLU: Mlut_08550
            RMU: RMDY18_07530
            RDN: HMPREF0733_12198(ilvC)
            BCV: Bcav_1410
            BFA: Bfae_18790
            JDE: Jden_1708
            KSE: Ksed_09880
            XCE: Xcel_2384
            SKE: Sked_10700
            CFL: Cfla_1165
            ICA: Intca_2361
            PAC: PPA1372
            PAK: HMPREF0675_4420(ilvC)
            PFR: PFREUD_13390(ilvC)
            NCA: Noca_2140 Noca_3390
            KFL: Kfla_4886
            TFU: Tfu_0613
            NDA: Ndas_0173
            TCU: Tcur_3552
            SRO: Sros_8057
            FRA: Francci3_3638
            FRE: Franean1_1092
            FRI: FraEuI1c_1017
            FAL: FRAAL5849(ilvC)
            ACE: Acel_0708
            NML: Namu_1468
            GOB: Gobs_4071
            KRA: Krad_1337
            SEN: SACE_6157(ilvC)
            SVI: Svir_08890
            TBI: Tbis_2819
            AMD: AMED_1687(ilvC)
            AMI: Amir_6019
            STP: Strop_1235
            SAQ: Sare_1125
            MAU: Micau_1304
            MIL: ML5_1550
            CAI: Caci_7780
            SNA: Snas_4354
            MCU: HMPREF0573_11480(ilvC)
            BLO: BL0530(ilvC1) BL0531(ilvC2)
            BLJ: BLD_1326(ilvC1) BLD_1327(ilvC2)
            BLN: Blon_0131 Blon_0136
            BLL: BLJ_0103 BLJ_0105
            BLB: BBMN68_1262(ilvC1) BBMN68_1263(ilvC2)
            BAD: BAD_0081(ilvC2) BAD_0082(ilvC1)
            BLA: BLA_0138(ilvC)
            BLC: Balac_0148
            BLT: Balat_0148
            BDE: BDP_0118(ilvC) BDP_0119(ilvC)
            BBI: BBIF_0185(ilvC1) BBIF_0186(ilvC2)
            BBP: BBPR_0147(ilvC) BBPR_0148(ilvC)
            RXY: Rxyl_3127
            CWO: Cwoe_3563
            AFO: Afer_1545
            CCU: Ccur_08830
            ELE: Elen_1875
            SSM: Spirs_0830 Spirs_1606
            LIL: LA_4242(ilvC)
            LIC: LIC13393(ilvC)
            LBJ: LBJ_2914(ilvC)
            LBL: LBL_0149(ilvC)
            LBI: LEPBI_I0708(ilvC)
            LBF: LBF_0685(ilvC)
            BHY: BHWA1_01045(ilvC)
            BRM: Bmur_2218
            BPO: BP951000_0188(ilvC)
            ABA: Acid345_3106
            ACA: ACP_3464(ilvC)
            TSA: AciPR4_1129
            SUS: Acid_0178
            BTH: BT_2074
            BFR: BF3758
            BFS: BF3546
            BVU: BVU_2558
            BHL: Bache_3319
            PDI: BDI_2069
            PPN: Palpr_0140
            APS: CFPG_336
            PRU: PRU_0551(ilvC)
            SRU: SRU_2147(ilvC)
            SRM: SRM_02368(ilvC)
            RMR: Rmar_0738
            CHU: CHU_1149(ilvC)
            DFE: Dfer_3679
            SLI: Slin_5912
            LBY: Lbys_2276
            MTT: Ftrac_1636
            CPI: Cpin_1923
            PHE: Phep_3422
            GFO: GFO_2110(ilvC)
            FJO: Fjoh_2860
            FPS: FP0446(ilvC)
            RBI: RB2501_14429
            ZPR: ZPR_2800
            FBC: FB2170_12286
            CAO: Celal_3664
            SMG: SMGWSS_262(ilvC)
            SMS: SMDSEM_275(ilvC)
            SMH: DMIN_02570
            SUM: SMCARI_285(ilvC)
            BBL: BLBBGE_554(ilvC)
            BPI: BPLAN_086(ilvC)
            FSU: Fisuc_0313
            LBA: Lebu_1703
            STR: Sterm_0116
            IPO: Ilyop_1157
            OTE: Oter_3478 Oter_3480
            CAA: Caka_1137
            MIN: Minf_1744(ilvC)
            AMU: Amuc_1178
            RBA: RB9869(ilvC)
            PSL: Psta_4689
            PLM: Plim_1193
            IPA: Isop_0283
            RSD: TGRD_684
            TAI: Taci_1608
            SYN: sll1363(ilvC)
            SYW: SYNW1650(ilvC)
            SYC: syc0010_c(ilvC)
            SYF: Synpcc7942_1552
            SYD: Syncc9605_0839
            SYE: Syncc9902_1550
            SYG: sync_0725(ilvC)
            SYR: SynRCC307_0594(ilvC)
            SYX: SynWH7803_1765(ilvC)
            SYP: SYNPCC7002_A1278(ilvC)
            CYA: CYA_0246(ilvC)
            CYB: CYB_1789(ilvC)
            TEL: tll2254(ilvC)
            MAR: MAE_09700(ilvC)
            CYT: cce_2120(ilvC)
            CYP: PCC8801_0991
            CYC: PCC7424_2051
            CYN: Cyan7425_1343
            CYH: Cyan8802_1020
            CYJ: Cyan7822_0132
            GVI: gvip374(ilvC)
            ANA: all2315
            NPU: Npun_F3618
            AVA: Ava_0133
            NAZ: Aazo_0343
            PMA: Pro1389(ilvC)
            PMM: PMM1315(ilvC)
            PMT: PMT0313
            PMN: PMN2A_0881
            PMI: PMT9312_1412
            PMB: A9601_15141(ilvC)
            PMC: P9515_14761(ilvC)
            PMF: P9303_20051(ilvC)
            PMG: P9301_15011(ilvC)
            PMH: P9215_15441(ilvC)
            PMJ: P9211_13631
            PME: NATL1_17361(ilvC)
            TER: Tery_4335
            AMR: AM1_5555(ilvC)
            CTE: CT0616(ilvC)
            CPC: Cpar_0632
            CCH: Cag_1902
            CPH: Cpha266_0851
            CPB: Cphamn1_1719
            CLI: Clim_0739
            PVI: Cvib_1172
            PLT: Plut_0604
            PPH: Ppha_2172
            PAA: Paes_0741
            CTS: Ctha_1629
            DET: DET0831(ilvC)
            DEH: cbdb_A811(ilvC)
            DEB: DehaBAV1_0750
            DEV: DhcVS_735(ilvC)
            DEG: DehalGT_0711
            DLY: Dehly_0668
            RRS: RoseRS_1966
            RCA: Rcas_1555
            CAU: Caur_0165
            CAG: Cagg_1242
            CHL: Chy400_0177
            HAU: Haur_4447
            TRO: trd_0625(ilvC)
            STI: Sthe_1555
            ATM: ANT_03280(ilvC)
            DRA: DR_1519
            DGE: Dgeo_0600
            DDR: Deide_16830(ilvC)
            DMR: Deima_1512
            TRA: Trad_0206
            TTH: TTC0850
            TTJ: TTHA1211
            TSC: TSC_c08410(ilvC)
            MRB: Mrub_1907
            MSV: Mesil_2142
            OPR: Ocepr_0803
            AAE: aq_1245(ilvC)
            HYA: HY04AAS1_0065
            HTH: HTH_1630(ilvC)
            TAL: Thal_0897
            SUL: SYO3AOP1_0228
            SAF: SULAZ_0081(ilvC)
            PMX: PERMA_0155(ilvC)
            TAM: Theam_0459
            TMA: TM0550
            TPT: Tpet_0370
            TRQ: TRQ2_0387
            TNA: CTN_0118
            TNP: Tnap_0330
            PMO: Pmob_1590
            DTH: DICTH_1062(ilvC)
            DTU: Dtur_1189
            TYE: THEYE_A0653(ilvC)
            NDE: NIDE0999(ilvC)
            TTR: Tter_0188
            DDF: DEFDS_1665(ilvC)
            DAP: Dacet_0417
            CNI: Calni_0830
            MJA: MJ_1543
            MFE: Mefer_1479
            MVU: Metvu_0649
            MFS: MFS40622_0744
            MIF: Metin_0097
            MMP: MMP0654(ilvC)
            MMQ: MmarC5_0922
            MMX: MmarC6_0233
            MMZ: MmarC7_1680
            MAE: Maeo_1175
            MVN: Mevan_1538
            MVO: Mvol_0798
            MAC: MA3790(ilvC)
            MBA: Mbar_A0220
            MMA: MM_0668
            MBU: Mbur_0708
            MMH: Mmah_0836
            MEV: Metev_0746
            MTP: Mthe_0112
            MHU: Mhun_1245
            MLA: Mlab_0019 Mlab_0602
            MEM: Memar_2172
            MPI: Mpet_0410
            MBN: Mboo_0481
            MPL: Mpal_0082
            MPD: MCP_2585(ilvC)
            MTH: MTH1442
            MMG: MTBMA_c00290(ilvC)
            MST: Msp_0022(ilvC)
            MSI: Msm_1222
            MRU: mru_2110(ilvC)
            MFV: Mfer_0054
            MKA: MK0832(ilvC)
            AFU: AF1985(ilvC)
            APO: Arcpr_0347
            FPL: Ferp_0388
            HMA: rrnAC0332(ilvC)
            HWA: HQ2704A(ilvC)
            NPH: NP2198A(ilvC)
            HLA: Hlac_0873
            HUT: Huta_0641
            HMU: Hmuk_2654
            HTU: Htur_2767
            NMG: Nmag_0903
            HVO: HVO_1506(ilvC)
            HJE: HacjB3_05845 HacjB3_10540
            HBO: Hbor_17320
            PTO: PTO1073
            PAB: PAB0889(ilvC)
            PFU: PF0936
            RCI: LRC519(ilvC)
            IHO: Igni_0608
            IAG: Igag_1561
            SSO: SSO0576(ilvC-1) SSO1322(ilvC-2) SSO1942(ilvC-3)
            STO: ST1445
            SAI: Saci_1559
            SIS: LS215_0667 LS215_1663
            SIA: M1425_0953 M1425_1555
            SIM: M1627_1009 M1627_1671
            SID: M164_0949 M164_1552
            SIY: YG5714_0707 YG5714_1559
            SIN: YN1551_1277 YN1551_2489
            SII: LD85_0896 LD85_1763
            MSE: Msed_1927
            PAI: PAE3298
            PIS: Pisl_0552
            PCL: Pcal_1755
            PAS: Pars_1722
            CMA: Cmaq_1168
            TNE: Tneu_1541
            VDI: Vdis_0688 Vdis_1748
            ASC: ASAC_1365
            NMR: Nmar_0959
            CSY: CENSYa_1385
            KCR: Kcr_0639
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.86
            IUBMB Enzyme Nomenclature: 1.1.1.86
            ExPASy - ENZYME nomenclature database: 1.1.1.86
            BRENDA, the Enzyme Database: 1.1.1.86
            CAS: 9075-02-9
///
ENTRY       EC 1.1.1.87                 Enzyme
NAME        homoisocitrate dehydrogenase;
            2-hydroxy-3-carboxyadipate dehydrogenase;
            3-carboxy-2-hydroxyadipate dehydrogenase;
            homoisocitric dehydrogenase;
            (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase
            (decarboxylating);
            3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating);
            HICDH
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase
            (decarboxylating)
REACTION    (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate +
            CO2 + NADH + H+ [RN:R01934]
ALL_REAC    R01934;
            (other) R01936 R04862
SUBSTRATE   (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate [CPD:C05662];
            NAD+ [CPD:C00003]
PRODUCT     2-oxoadipate [CPD:C00322];
            CO2 [CPD:C00011];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Forms part of the lysine biosynthesis pathway in fungi [3].
REFERENCE   1  [PMID:4284830]
  AUTHORS   Strassman M, Ceci LN.
  TITLE     Enzymatic formation of alpha-ketoadipic acid from homoisocitric
            acid.
  JOURNAL   J. Biol. Chem. 240 (1965) 4357-61.
  ORGANISM  Torulopsis utilis
REFERENCE   2  [PMID:4395693]
  AUTHORS   Rowley B, Tucci AF.
  TITLE     Homoisocitric dehydrogenase from yeast.
  JOURNAL   Arch. Biochem. Biophys. 141 (1970) 499-510.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
REFERENCE   3  [PMID:10714900]
  AUTHORS   Zabriskie TM, Jackson MD.
  TITLE     Lysine biosynthesis and metabolism in fungi.
  JOURNAL   Nat. Prod. Rep. 17 (2000) 85-97.
  ORGANISM  Saccharomyces cerevisiae [GN:sce]
PATHWAY     ec00300  Lysine biosynthesis
            ec01100  Metabolic pathways
ORTHOLOGY   K05824  homoisocitrate dehydrogenase
GENES       SCE: YIL094C(LYS12)
            AGO: AGOS_ADL214C
            KLA: KLLA0E08339g
            LTH: KLTH0G10384g
            PPA: PAS_chr2-2_0168
            VPO: Kpol_1003p39
            ZRO: ZYRO0A01914g
            CGR: CAGL0G02585g
            DHA: DEHA2C16852g
            PIC: PICST_50442(LYS12)
            LEL: LELG_00189
            CAL: CaO19.10060(LYS12)
            CTP: CTRG_00945
            CDU: CD36_26410
            YLI: YALI0D10593g
            NCR: NCU02954
            PAN: PODANSg09901
            MGR: MGG_01566(MG01566.4)
            FGR: FG01392.1
            SSL: SS1G_02537
            BFU: BC1G_01260
            ANI: AN5206.2
            AFM: AFUA_6G07390
            NFI: NFIA_053070
            AOR: AO090005001561
            ANG: An15g02490
            AFV: AFLA_087950
            ACT: ACLA_081560
            PCS: Pc18g05890
            CIM: CIMG_08027
            CPW: CPC735_020650
            URE: UREG_02316
            PNO: SNOG_01047
            TML: GSTUM_00011274001
            SPO: SPAC31G5.04
            CNE: CND03850
            CNB: CNBD2460
            LBC: LACBIDRAFT_229977
            CCI: CC1G_00055
            SCM: SCHCODRAFT_46722
            UMA: UM04873.1
            MGL: MGL_3003
            NGR: NAEGRDRAFT_79802
            DRA: DR_1674
            TTH: TTC1012
            TTJ: TTHA1378
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.87
            IUBMB Enzyme Nomenclature: 1.1.1.87
            ExPASy - ENZYME nomenclature database: 1.1.1.87
            BRENDA, the Enzyme Database: 1.1.1.87
            CAS: 9067-90-7
///
ENTRY       EC 1.1.1.88                 Enzyme
NAME        hydroxymethylglutaryl-CoA reductase;
            beta-hydroxy-beta-methylglutaryl coenzyme A reductase;
            beta-hydroxy-beta-methylglutaryl CoA-reductase;
            3-hydroxy-3-methylglutaryl coenzyme A reductase;
            hydroxymethylglutaryl coenzyme A reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-mevalonate:NAD+ oxidoreductase (CoA-acylating)
REACTION    (R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2
            NADH + 2 H+ [RN:R02081]
ALL_REAC    R02081
SUBSTRATE   (R)-mevalonate [CPD:C00418];
            CoA [CPD:C00010];
            NAD+ [CPD:C00003]
PRODUCT     3-hydroxy-3-methylglutaryl-CoA [CPD:C00356];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1
  AUTHORS   Fimognari, G.M. and Rodwell, V.W.
  TITLE     Substrate-competitive inhibition of bacterial
            mevalonate:nicotinamide-adenine dinucleotide oxidoreductase
            (acylating CoA).
  JOURNAL   Biochemistry 4 (1965) 2086-2090.
PATHWAY     ec00900  Terpenoid backbone biosynthesis
            ec01110  Biosynthesis of secondary metabolites
ORTHOLOGY   K00054  hydroxymethylglutaryl-CoA reductase
GENES       PPF: Pput_3073
            TTU: TERTU_3247
            LPN: lpg2052
            LPF: lpl2030
            LPP: lpp2035
            LPC: LPC_1538(mvaA)
            LPA: lpa_02994
            LLO: LLO_2093(mvaA)
            BCH: Bcen2424_3505
            BCM: Bcenmc03_4013
            BCJ: BCAM0531(mvaA)
            BPT: Bpet3342(mvaA)
            DAC: Daci_0287
            VPE: Varpa_0083
            CTT: CtCNB1_3119
            ADN: Alide_3812
            HSE: Hsero_3034(mvaA)
            BBA: Bd1627
            MXA: MXAN_5020
            SCL: sce3010
            HOH: Hoch_3406 Hoch_5714
            SIL: SPOA0163(mvaA)
            OIH: OB0224
            SAU: SA2333(mvaA)
            SAV: SAV2545(mvaA)
            SAW: SAHV_2529(mvaA)
            SAH: SaurJH1_2621
            SAJ: SaurJH9_2568
            SAM: MW2466(mvaA)
            SAS: SAS2431
            SAR: SAR2625(mvaA)
            SAC: SACOL2560
            SAX: USA300HOU_2539
            SAA: SAUSA300_2483
            SAO: SAOUHSC_02859
            SAE: NWMN_2445(mvaA)
            SAD: SAAV_2611
            SAB: SAB2419c(mvaA)
            SEP: SE2109
            SER: SERP2121
            SHA: SH0511(mvaA)
            SSP: SSP0326
            SCA: Sca_1883(mvaA)
            SLG: SLGD_00448
            LMO: lmo0825
            LMF: LMOf2365_0844
            LMH: LMHCC_1803
            LMC: Lm4b_00843
            LMN: LM5578_0904
            LMY: LM5923_0859
            LIN: lin0821
            LWE: lwe0819(mvaA)
            LSG: lse_0725
            LLA: L10433(mvaA)
            LLK: LLKF_1694(mvaA)
            LLC: LACR_1664
            LLM: llmg_0931(mvaA)
            SPY: SPy_0880(mvaS.1)
            SPZ: M5005_Spy_0686
            SPM: spyM18_0941(mvaS1)
            SPG: SpyM3_0599(mvaS.1)
            SPS: SPs1254
            SPH: MGAS10270_Spy0744
            SPI: MGAS10750_Spy0778
            SPJ: MGAS2096_Spy0758
            SPK: MGAS9429_Spy0742
            SPF: SpyM51122(mvaA)
            SPA: M6_Spy0703
            SPB: M28_Spy0666
            SOZ: Spy49_0694c(mvaS1)
            SPN: SP_1726
            SPD: SPD_1536
            SPR: spr1570(mvaA)
            SPW: SPCG_1698(mvaA)
            SPX: SPG_1631(mvaA)
            SNE: SPN23F_17270(mvaA)
            SPV: SPH_1835
            SNM: SP70585_1765
            SJJ: SPJ_1621
            SNT: SPT_1664
            SNC: HMPREF0837_11969(mvaA)
            SNB: SP670_1819
            SNP: SPAP_1731
            SAG: SAG1317
            SAN: gbs1387
            SAK: SAK_1348
            SMU: SMU.942(mvaA)
            SMC: SmuNN2025_1085(mvaA)
            STC: str0576(mvaA)
            STL: stu0576(mvaA)
            STE: STER_0620
            SSA: SSA_0337(mvaA)
            SSU: SSU05_1642
            SSV: SSU98_1653
            SSB: SSUBM407_1530(mvaA)
            SSI: SSU1454(mvaA)
            SSS: SSUSC84_1483(mvaA)
            SGO: SGO_0243
            SEQ: SZO_08870
            SEZ: Sez_1080(hmgA)
            SEU: SEQ_1108
            SUB: SUB0769(mvaA)
            SDS: SDEG_0842(mvaS1)
            SGA: GALLO_1260
            SMB: smi_1618
            LPL: lp_0447(mvaA)
            LPJ: JDM1_0375(mvaA)
            LPS: LPST_C0374(mvaA)
            LJO: LJ1608
            LJF: FI9785_1399(mvaA)
            LAC: LBA0627(hmdH)
            LSA: LSA1485(mvaA)
            LSL: LSL_0224
            LDB: Ldb0880(mvaA)
            LBU: LBUL_0805
            LDE: LDBND_0809
            LBR: LVIS_0450
            LCA: LSEI_1786
            LCB: LCABL_20040(mvaA)
            LCZ: LCAZH_1777
            LGA: LGAS_1373
            LRE: Lreu_0206
            LRF: LAR_0196
            LHE: lhv_0662
            LFE: LAF_0181
            LRH: LGG_01838(mvaA)
            LRL: LC705_01821(mvaA)
            LCR: LCRIS_00631(mvaA)
            LAM: LA2_03245
            PPE: PEPE_0258
            EFA: EF1364
            LME: LEUM_0335
            LCI: LCK_00238(mvaA)
            LKI: LKI_04880
            LGS: LEGAS_1641(mvaA)
            ACL: ACL_0223
            RER: RER_34980(mvaA)
            GVA: HMPREF0424_0360
            GVG: HMPREF0421_21108(mvaA)
            WCH: wcw_1117(mvaA)
            BBU: BB0685
            BBZ: BbuZS7_0705
            BGA: BG0708(mvaA)
            BAF: BAPKO_0729(mvaA)
            BTU: BT0685
            BHR: BH0685
            BDU: BDU_688(mvaA)
            BRE: BRE_691(mvaA)
            GFO: GFO_2973(hmgA)
            FPS: FP2341
            RBI: RB2501_08860
            ZPR: ZPR_0646
            CAT: CA2559_04185
            RAN: Riean_1569
            FBC: FB2170_08454
            CAO: Celal_0919
            FBA: FIC_02280
            LBA: Lebu_0850
            SMF: Smon_1290
            RRS: RoseRS_0431
            RCA: Rcas_0981
            CAU: Caur_0236
            CAG: Cagg_1141
            CHL: Chy400_0251
            HAU: Haur_3539
            ATM: ANT_28820(mvaA)
            MTP: Mthe_0936
            MPD: MCP_0218(hmgA-1)
            AFU: AF1736(mvaA)
            APO: Arcpr_1276
            FPL: Ferp_1542
            TAC: Ta0406m(HMG1)
            TVO: TVN1168
            PTO: PTO1143
            ABI: Aboo_1461
            RCI: RCIX376(hmgA)
            SMR: Smar_0178
            SHC: Shell_0645
            DKA: DKAM_0720
            DMU: Desmu_0460
            TAG: Tagg_0332
            IAG: Igag_1535
            TPE: Tpen_0927
            NMR: Nmar_1560
            CSY: CENSYa_2026
            KCR: Kcr_0563
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.88
            IUBMB Enzyme Nomenclature: 1.1.1.88
            ExPASy - ENZYME nomenclature database: 1.1.1.88
            BRENDA, the Enzyme Database: 1.1.1.88
            CAS: 37250-24-1
///
ENTRY       EC 1.1.1.89       Obsolete  Enzyme
NAME        Deleted entry
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
COMMENT     Deleted entry: dihydroxyisovalerate dehydrogenase (isomerizing). Now
            included with EC 1.1.1.86 ketol-acid reductoisomerase (EC 1.1.1.89
            created 1972, deleted 1976)
///
ENTRY       EC 1.1.1.90                 Enzyme
NAME        aryl-alcohol dehydrogenase;
            p-hydroxybenzyl alcohol dehydrogenase;
            benzyl alcohol dehydrogenase;
            coniferyl alcohol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     aryl-alcohol:NAD+ oxidoreductase
REACTION    an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+
            [RN:R01487]
ALL_REAC    R01487 > R01763 R02611 R04304 R05282 R05347 R05348;
            (other) R02229
SUBSTRATE   aromatic alcohol [CPD:C03485];
            NAD+ [CPD:C00003]
PRODUCT     aromatic aldehyde [CPD:C00193];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     A group of enzymes with broad specificity towards primary alcohols
            with an aromatic or cyclohex-1-ene ring, but with low or no activity
            towards short-chain aliphatic alcohols.
REFERENCE   1  [PMID:5778658]
  AUTHORS   Suhara K, Takemori S, Katagiri M.
  TITLE     The purification and properties of benzylalcohol dehydrogenase from
            Pseudomonas sp.
  JOURNAL   Arch. Biochem. Biophys. 130 (1969) 422-9.
  ORGANISM  Pseudomonas sp.
REFERENCE   2
  AUTHORS   Yamanaka, K. and Minoshima, R.
  TITLE     Identification and characterization of a nicotinamide adenine
            dinucleotide-dependent para-hydroxybenzyl alcohol-dehydrogenase from
            Rhodopseudomonas acidophila M402.
  JOURNAL   Agric. Biol. Chem. 48 (1984) 1161-1171.
PATHWAY     ec00350  Tyrosine metabolism
            ec00360  Phenylalanine metabolism
            ec00622  Xylene degradation
            ec00623  Toluene degradation
            ec00930  Caprolactam degradation
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00055  aryl-alcohol dehydrogenase
GENES       KPN: KPN_01945
            KPE: KPK_2404(areB)
            KPU: KP1_3012
            KVA: Kvar_2358
            SPE: Spro_1170 Spro_1956
            SMT: Smal_3489
            PAP: PSPA7_4414
            PPG: PputGB1_3245
            ACI: ACIAD1429(areB) ACIAD1578
            PAT: Patl_3763
            CSA: Csal_0349
            BCN: Bcen_1312
            BCH: Bcen2424_6517
            BCM: Bcenmc03_6119
            BAM: Bamb_5580
            BAC: BamMC406_6306
            BRH: RBRH_02691
            BPT: Bpet1387(areB)
            NEU: NE0742
            NMU: Nmul_A1473
            EBA: ebA3166(adh)
            HOH: Hoch_1664
            SFU: Sfum_0304
            PLA: Plav_0089
            ATU: Atu5202
            RET: RHE_PD00126(ypd00032)
            REC: RHECIAT_PB0000141 RHECIAT_PC0000920
            RLE: pRL120506(xylB)
            RLT: Rleg2_4902
            RLG: Rleg_4812
            BBT: BBta_6644(xylB)
            MSL: Msil_3430
            CCR: CC_2396
            CCS: CCNA_02479
            HNE: HNE_1493 HNE_2119
            NAR: Saro_3899
            SJP: SJA_C2-04960
            AZL: AZL_c01090
            BHA: BH2011
            BWE: BcerKBAB4_3334
            BPU: BPUM_1147
            PJD: Pjdr2_6217
            LPL: lp_3054
            LPJ: JDM1_2435
            LPS: LPST_C2513
            LSA: LSA0542
            LSL: LSL_1748(adhC)
            LBR: LVIS_0911
            LRE: Lreu_1578
            LRF: LAR_1480
            LFE: LAF_0797
            LRH: LGG_02693(xylB)
            LRL: LC705_02676(xylB)
            LAM: LA2_04575
            CLJ: CLJU_c16150
            MSM: MSMEG_2034 MSMEG_4039
            MGI: Mflv_0725
            MSP: Mspyr1_01060
            CGT: cgR_2372
            NFA: nfa25980
            RHA: RHA1_ro02648 RHA1_ro02661 RHA1_ro03285(xylB)
            RER: RER_07910(adhA) RER_47820(adhB)
            ROP: ROP_45670(adhA) ROP_46940 ROP_49550(adhB)
            REQ: REQ_04010
            TPR: Tpau_2391
            SCO: SCO6442(SC9B5.09) SCO6782(SC6A5.31c)
            SGR: SGR_6401 SGR_857
            SCB: SCAB_9131
            NCA: Noca_1176 Noca_2120
            TCU: Tcur_1032
            FRI: FraEuI1c_5052
            FAL: FRAAL4756(xylB)
            SVI: Svir_28790
            AMD: AMED_3271
            AMI: Amir_6807
            CAI: Caci_2709 Caci_6462
            RXY: Rxyl_1758
            NDE: NIDE0023(xylB)
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.90
            IUBMB Enzyme Nomenclature: 1.1.1.90
            ExPASy - ENZYME nomenclature database: 1.1.1.90
            UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.90
            BRENDA, the Enzyme Database: 1.1.1.90
            CAS: 37250-26-3
///
ENTRY       EC 1.1.1.91                 Enzyme
NAME        aryl-alcohol dehydrogenase (NADP+);
            aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide
            phosphate);
            coniferyl alcohol dehydrogenase;
            NADPH-linked benzaldehyde reductase;
            aryl-alcohol dehydrogenase (NADP+)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     aryl-alcohol:NADP+ oxidoreductase
REACTION    an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH + H+
            [RN:R01488]
ALL_REAC    R01488
SUBSTRATE   aromatic alcohol [CPD:C03485];
            NADP+ [CPD:C00006]
PRODUCT     aromatic aldehyde [CPD:C00193];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also acts on some aliphatic aldehydes, but cinnamaldehyde was the
            best substrate found.
REFERENCE   1  [PMID:4389864]
  AUTHORS   Gross GG, Zenk MH.
  TITLE     [Reduction of aromatic acids to aldehydes and alcohols in the
            cell-free system. 2. Purification and properties of aryl-alcohol:
            NADP-oxidoreductase from Neurospora crassa]
  JOURNAL   Eur. J. Biochem. 8 (1969) 420-5.
  ORGANISM  Neurospora crassa [GN:ncr]
ORTHOLOGY   K05882  aryl-alcohol dehydrogenase (NADP+)
GENES       TET: TTHERM_00962040
            BMA: BMAA1370
            BMV: BMASAVP1_0355
            BML: BMA10229_0633
            BMN: BMA10247_A0938
            BPM: BURPS1710b_A2461(mocA)
            BPL: BURPS1106A_A1195
            BPD: BURPS668_A1269
            BUR: Bcep18194_A4943 Bcep18194_A6427 Bcep18194_B0520 Bcep18194_B1321
                 Bcep18194_B2226 Bcep18194_B2826 Bcep18194_B2914 Bcep18194_B3141
            RET: RHE_CH02454(ypch00822) RHE_CH02805(ypch00965)
                 RHE_CH03774(ypch01349)
            RLE: RL2983
            BRA: BRADO6605
            BBT: BBta_0931
            GBE: GbCGDNIH1_0531
            MJL: Mjls_0023
            CGL: NCgl0099(cgl0100)
            RHA: RHA1_ro00240 RHA1_ro01880
            ART: Arth_3453
            FRA: Francci3_3416
            FAL: FRAAL3972 FRAAL4438 FRAAL5526
            SEN: SACE_0624(mocA) SACE_1269
            AVA: Ava_0108 Ava_4145 Ava_5010
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.91
            IUBMB Enzyme Nomenclature: 1.1.1.91
            ExPASy - ENZYME nomenclature database: 1.1.1.91
            BRENDA, the Enzyme Database: 1.1.1.91
            CAS: 37250-27-4
///
ENTRY       EC 1.1.1.92                 Enzyme
NAME        oxaloglycolate reductase (decarboxylating)
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     D-glycerate:NAD(P)+ oxidoreductase (carboxylating)
REACTION    D-glycerate + NAD(P)+ + CO2 = 2-hydroxy-3-oxosuccinate + NAD(P)H + 2
            H+ [RN:R01749 R01750]
ALL_REAC    R01749 R01750
SUBSTRATE   D-glycerate [CPD:C00258];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006];
            CO2 [CPD:C00011]
PRODUCT     2-hydroxy-3-oxosuccinate [CPD:C03459];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Also reduces hydroxypyruvate to D-glycerate and glyoxylate to
            glycolate.
REFERENCE   1  [PMID:4385076]
  AUTHORS   Kohn LD, Jakoby WB.
  TITLE     Tartaric acid metabolism. VI. Crystalline oxaloglycolate reductive
            decarboxylase.
  JOURNAL   J. Biol. Chem. 243 (1968) 2486-93.
  ORGANISM  Pseudomonas putida
PATHWAY     ec00630  Glyoxylate and dicarboxylate metabolism
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.92
            IUBMB Enzyme Nomenclature: 1.1.1.92
            ExPASy - ENZYME nomenclature database: 1.1.1.92
            BRENDA, the Enzyme Database: 1.1.1.92
            CAS: 37250-28-5
///
ENTRY       EC 1.1.1.93                 Enzyme
NAME        tartrate dehydrogenase;
            mesotartrate dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     tartrate:NAD+ oxidoreductase
REACTION    tartrate + NAD+ = oxaloglycolate + NADH + H+ [RN:R02545 R06180]
ALL_REAC    R02545 R06180
SUBSTRATE   tartrate [CPD:C00898];
            NAD+ [CPD:C00003]
PRODUCT     oxaloglycolate [CPD:C03459];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COFACTOR    Manganese [CPD:C00034]
COMMENT     meso-tartrate and (R,R)-tartrate act as substrates. Requires Mn2+
            and a monovalent cation.
REFERENCE   1  [PMID:4297261]
  AUTHORS   Kohn LD, Packman PM, Allen RH, Jakoby WB.
  TITLE     Tartaric acid metabolism. V. Crystalline tartrate dehydrogenase.
  JOURNAL   J. Biol. Chem. 243 (1968) 2479-85.
  ORGANISM  Pseudomonas putida
PATHWAY     ec00630  Glyoxylate and dicarboxylate metabolism
ORTHOLOGY   K07246  tartrate dehydrogenase/decarboxylase / D-malate
                    dehydrogenase
GENES       ECO: b1800(dmlA)
            ECJ: JW1789(yeaU)
            ECD: ECDH10B_1938(yeaU)
            EBW: BWG_1613(yeaU)
            ECE: Z2843(yeaU)
            ECS: ECs2509
            ECF: ECH74115_2526(ttuC)
            ETW: ECSP_2372(yeaU)
            EOJ: ECO26_2569(yeaU)
            EOI: ECO111_2306(yeaU)
            EOH: ECO103_1989(yeaU)
            EOK: G2583_2247(yeaU)
            ECX: EcHS_A1888(ttuC)
            ECW: EcE24377A_2026(ttuC)
            ECM: EcSMS35_1388(ttuC)
            ECY: ECSE_1974
            ECR: ECIAI1_1869(yeaU)
            ECK: EC55989_1973(yeaU)
            ECT: ECIAI39_1253(yeaU)
            EUM: ECUMN_2090(yeaU)
            ECL: EcolC_1833
            EBR: ECB_01770(yeaU)
            EBD: ECBD_1842
            YPE: YPO2496
            YPK: y1692
            YPA: YPA_1991
            YPN: YPN_2090
            YPM: YP_2311(leuB1)
            YPP: YPDSF_1907
            YPG: YpAngola_A1756
            YPZ: YPZ3_2138
            YPS: YPTB2532
            YPI: YpsIP31758_1512
            YPY: YPK_1616
            YPB: YPTS_2627
            SSN: SSON_1361(yeaU)
            SBO: SBO_1288(yeaU)
            SBC: SbBS512_E2058(ttuC)
            SDY: SDY_1701(yeaU)
            EBI: EbC_44840(ttuC\')
            ESC: Entcl_2813
            KPN: KPN_01015
            KPE: KPK_3185(ttuC) KPK_3545
            KPU: KP1_1998 KP1_2292
            KVA: Kvar_3059 Kvar_3364
            CKO: CKO_01178
            CRO: ROD_11931(ttuC') ROD_18421
            DDA: Dd703_3166
            DDC: Dd586_0850
            DDD: Dda3937_01460(yeaU)
            DZE: Dd1591_3237
            XNE: XNC1_0562(yeaU)
            PAM: PANA_0325(yeaU)
            PVA: Pvag_3587(yeaU) Pvag_pPag30035(ttuC)
            PAO: Pat9b_0374 Pat9b_4594
            MSU: MS1105(leuB)
            PPG: PputGB1_2196
            PPW: PputW619_1230
            PST: PSPTO_2662
            PSB: Psyr_2396
            PSP: PSPPH_1578 PSPPH_2554
            PFL: PFL_3649
            PFS: PFLU4038
            PEN: PSEEN2132
            ACD: AOLE_15445
            ACB: A1S_0849
            ABY: ABAYE2964
            ABC: ACICU_00802
            ABN: AB57_0897
            ABB: ABBFA_002763
            MAQ: Maqu_2209
            AEH: Mlg_0489
            HHA: Hhal_0829
            CSA: Csal_2776
            HEL: HELO_1564(yeaU)
            ABO: ABO_0510(tdh)
            MMW: Mmwyl1_3080
            RSO: RSp0996(ttuC2) RSp1612(ttuC)
            RSL: RPSI07_mp0990 RPSI07_mp1032 RPSI07_mp1717
            REU: Reut_A0462 Reut_B4115 Reut_C5899
            REH: H16_A0477(leuB1) H16_A2133(leuB2)
            RME: Rmet_0404
            CTI: RALTA_A0433(ttuC3) RALTA_B0889(ttuC1)
            BMA: BMAA0011(ttuC)
            BMV: BMASAVP1_1159(ttuC)
            BML: BMA10229_1440(ttuC)
            BMN: BMA10247_A0014(ttuC)
            BPS: BPSS0011
            BPM: BURPS1710b_A1518
            BPL: BURPS1106A_A0014
            BPD: BURPS668_A0015
            BTE: BTH_II0013
            BVI: Bcep1808_3784
            BUR: Bcep18194_B3173
            BCN: Bcen_4654 Bcen_5152 Bcen_5538
            BCH: Bcen2424_3709 Bcen2424_5707 Bcen2424_5903
            BCM: Bcenmc03_3812 Bcenmc03_4532
            BCJ: BCAM0016 BCAM0743 BCAS0278
            BAM: Bamb_4976 Bamb_5440
            BAC: BamMC406_3119 BamMC406_3593
            BMU: Bmul_5024 Bmul_5317 Bmul_6024
            BMJ: BMULJ_03204(ttuC) BMULJ_03491(ttuC) BMULJ_05503(ttuC)
            BXE: Bxe_B1486 Bxe_B1620 Bxe_C0769 Bxe_C1229
            BPH: Bphy_4849 Bphy_5655 Bphy_6571
            BPY: Bphyt_5037 Bphyt_6098
            BGL: bglu_2g00150
            BGE: BC1002_3331 BC1002_4548 BC1002_5049
            PNU: Pnuc_1028
            PNE: Pnec_0838
            BPE: BP2291
            BPA: BPP2437 BPP4066
            BBR: BB1886 BB4539
            BPT: Bpet3077(yeaU1) Bpet4476(yeaU2)
            BAV: BAV2193
            AXY: AXYL_02112 AXYL_05245
            RFR: Rfer_0440 Rfer_0845 Rfer_2247
            POL: Bpro_1432 Bpro_3066
            PNA: Pnap_1016 Pnap_1632
            AAV: Aave_2087 Aave_2191
            AJS: Ajs_1120 Ajs_2860
            DIA: Dtpsy_1040 Dtpsy_2349
            VEI: Veis_2698 Veis_3186
            DAC: Daci_2113 Daci_2360
            VAP: Vapar_1027 Vapar_1788 Vapar_5638
            VPE: Varpa_0614 Varpa_1963 Varpa_4346 Varpa_5965
            CTT: CtCNB1_3465
            ADN: Alide_2759 Alide_3103
            MPT: Mpe_A0251
            HAR: HEAR3229(yeaU)
            MMS: mma_1237(ttuC)
            HSE: Hsero_1469(ttuC)
            LCH: Lcho_2992 Lcho_3176
            TIN: Tint_1132
            AZO: azo3860(yeaU)
            MLO: mll7044
            MES: Meso_4538
            PLA: Plav_0534
            SME: SMa1846
            SMD: Smed_5601
            RHI: NGR_b06350 NGR_b06550(ttuC)
            ATU: Atu3402
            ARA: Arad_7660 Arad_9169
            AVI: Avi_9120
            RET: RHE_PF00339(ypf00171)
            REC: RHECIAT_PC0000543
            RLE: RL0995 pRL110153(ttuC) pRL120629
            RLT: Rleg2_4411 Rleg2_4999 Rleg2_5311
            RLG: Rleg_5025
            BJA: blr2916 blr6570
            BRA: BRADO2534(yeaU) BRADO5094(ttuC)
            BBT: BBta_2879(yeaU) BBta_5565(ttuC)
            RPA: RPA1742(yeaU)
            RPB: RPB_3626
            RPC: RPC_4630
            RPD: RPD_1841
            RPT: Rpal_1942
            RPX: Rpdx1_3789
            OCA: OCAR_4377 OCAR_5921
            SNO: Snov_1602 Snov_1606
            MEX: Mext_4687
            MEA: Mex_1p5136(ttuC)
            MDI: METDI1373(ttuC) METDI5741(ttuC)
            MRD: Mrad2831_0770 Mrad2831_3993
            MET: M446_5246 M446_6783
            MPO: Mpop_4658 Mpop_5230
            MCH: Mchl_5152
            MNO: Mnod_1445 Mnod_5811
            CSE: Cseg_2987
            RSP: RSP_3388 RSP_3389 RSP_4031
            RSH: Rsph17029_3034 Rsph17029_3035
            RSK: RSKD131_3554 RSKD131_3555 RSKD131_4374
            PDE: Pden_4970
            DSH: Dshi_0775(ttuC)
            NAR: Saro_2935 Saro_3895
            ACR: Acry_0182 Acry_0647
            GDI: GDI_0420
            GDJ: Gdia_1585
            MAG: amb3176
            AZL: AZL_c03210(ttuC)
            APB: SAR116_0317 SAR116_1679
            BSU: BSU04000(ycsA)
            BSS: BSUW23_02070(ycsA)
            BHA: BH1070
            BCY: Bcer98_0765
            BLI: BL03389(ycsA)
            BLD: BLi03766(ycsA)
            BAY: RBAM_006090(ycsA)
            BAO: BAMF_0508(ycsA)
            BAE: BATR1942_18405
            BCL: ABC0841
            BPU: BPUM_0399(ycsA)
            BPF: BpOF4_11105
            BMQ: BMQ_1960(ycsA)
            BMD: BMD_1915(ycsA)
            OIH: OB0661
            GTN: GTNG_0291 GTNG_3379
            GMC: GY4MC1_3777
            LSP: Bsph_2213
            BBE: BBR47_56490
            BTS: Btus_3059
            CCE: Ccel_2567
            AMT: Amet_4274
            STH: STH2344
            AFN: Acfer_1764
            DSY: DSY3587
            DHD: Dhaf_1796
            MSM: MSMEG_1986
            MAB: MAB_4419
            MMC: Mmcs_2573
            MKM: Mkms_2618
            MJL: Mjls_2612
            RHA: RHA1_ro04803 RHA1_ro08803
            ROP: ROP_48970
            ACH: Achl_0442
            NDA: Ndas_0828 Ndas_1797
            SEN: SACE_3495(leuB1) SACE_4608
            SVI: Svir_30170
            AMD: AMED_7876(ttuC)
            SNA: Snas_1914 Snas_4827
            RXY: Rxyl_1183
            CWO: Cwoe_1031
            SUS: Acid_1530
            IPO: Ilyop_2603
            GAU: GAU_3552
            PSL: Psta_3744
            TRO: trd_1342
            STI: Sthe_3519
            KOL: Kole_0991
            HJE: HacjB3_03310 HacjB3_09780
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.93
            IUBMB Enzyme Nomenclature: 1.1.1.93
            ExPASy - ENZYME nomenclature database: 1.1.1.93
            BRENDA, the Enzyme Database: 1.1.1.93
            CAS: 37250-29-6
///
ENTRY       EC 1.1.1.94                 Enzyme
NAME        glycerol-3-phosphate dehydrogenase [NAD(P)+];
            L-glycerol-3-phosphate:NAD(P) oxidoreductase;
            glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide
            (phosphate));
            glycerol 3-phosphate dehydrogenase (NADP);
            glycerol-3-phosphate dehydrogenase [NAD(P)]
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase
REACTION    sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H +
            H+ [RN:R00842 R00844]
ALL_REAC    R00842 R00844
SUBSTRATE   sn-glycerol 3-phosphate [CPD:C00093];
            NAD+ [CPD:C00003];
            NADP+ [CPD:C00006]
PRODUCT     glycerone phosphate [CPD:C00111];
            NADH [CPD:C00004];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     The enzyme from Escherichia coli shows specificity for the B side of
            NADPH.
REFERENCE   1  [PMID:4389388]
  AUTHORS   Kito M, Pizer LI.
  TITLE     Purification and regulatory properties of the biosynthetic
            L-glycerol 3-phosphate dehydrogenase from Escherichia coli.
  JOURNAL   J. Biol. Chem. 244 (1969) 3316-23.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   2  [PMID:355254]
  AUTHORS   Edgar JR, Bell RM.
  TITLE     Biosynthesis in Escherichia coli fo sn-glycerol 3-phosphate, a
            precursor of phospholipid.
  JOURNAL   J. Biol. Chem. 253 (1978) 6348-53.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   3  [PMID:28326]
  AUTHORS   Edgar JR, Bell RM.
  TITLE     Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a
            precursor of phospholipid. Kinetic characterization of wild type and
            feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate
            dehydrogenase.
  JOURNAL   J. Biol. Chem. 253 (1978) 6354-63.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   4  [PMID:6767719]
  AUTHORS   Edgar JR, Bell RM.
  TITLE     Biosynthesis in Escherichia coli of sn-glycerol-3-phosphate, a
            precursor of phospholipid. Further kinetic characterization of wild
            type and feedback-resistant forms of the biosynthetic
            sn-glycerol-3-phosphate dehydrogenase.
  JOURNAL   J. Biol. Chem. 255 (1980) 3492-7.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00564  Glycerophospholipid metabolism
ORTHOLOGY   K00057  glycerol-3-phosphate dehydrogenase (NAD(P)+)
GENES       CRE: CHLREDRAFT_80188
            ECO: b3608(gpsA)
            ECJ: JW3583(gpsA)
            ECD: ECDH10B_3790(gpsA)
            EBW: BWG_3299(gpsA)
            ECE: Z5035(gpsA)
            ECS: ECs4486(gpsA)
            ECF: ECH74115_4981(gpsA)
            ETW: ECSP_4605(gpsA)
            EOJ: ECO26_4989(gpsA)
            EOI: ECO111_4433(gpsA)
            EOH: ECO103_4571(gpsA)
            ECG: E2348C_3857(gpsA)
            EOK: G2583_4347(gpsA)
            ECC: c4430(gpsA)
            ECP: ECP_3709(gpsA)
            ECI: UTI89_C4149(gpsA)
            ECV: APECO1_2847(gpsA)
            ECX: EcHS_A3820(gpsA)
            ECW: EcE24377A_4112(gpsA)
            ECM: EcSMS35_3945(gpsA)
            ECY: ECSE_3890(gpsA)
            ECR: ECIAI1_3781(gpsA)
            ECQ: ECED1_4294(gpsA)
            ECK: EC55989_4075(gpsA)
            ECT: ECIAI39_4129(gpsA)
            EUM: ECUMN_4125(gpsA)
            ECZ: ECS88_4025(gpsA)
            ECL: EcolC_0100(gpsA)
            EBR: ECB_03466(gpsA)
            EBD: ECBD_0117(gpsA)
            EFE: EFER_3602(gpsA)
            STY: STY4095(gpsA)
            STT: t3819(gpsA)
            STM: STM3700(gpsA)
            SPT: SPA3552(gpsA)
            SEK: SSPA3315(gpsA)
            SPQ: SPAB_04597(gpsA)
            SEI: SPC_3782(gpsA)
            SEC: SC3623(gpsA)
            SEH: SeHA_C4025(gpsA)
            SEE: SNSL254_A3980(gpsA)
            SEW: SeSA_A3899(gpsA)
            SEA: SeAg_B3918(gpsA)
            SED: SeD_A4086(gpsA)
            SEG: SG3731(gpsA)
            SET: SEN3522(gpsA)
            SES: SARI_03941(gpsA)
            YPE: YPO0068(gpsA)
            YPK: y0073(gpsA)
            YPA: YPA_3474(gpsA)
            YPN: YPN_3782(gpsA)
            YPM: YP_0068(gpsA)
            YPP: YPDSF_3837(gpsA)
            YPG: YpAngola_A0073(gpsA)
            YPZ: YPZ3_0062(gpsA)
            YPS: YPTB0064(gpsA)
            YPI: YpsIP31758_0079(gpsA)
            YPY: YPK_4137(gpsA)
            YPB: YPTS_0066(gpsA)
            YEN: YE0081(gpsA)
            SFL: SF3647(gpsA)
            SFX: S4121(gpsA)
            SFV: SFV_3923(gpsA)
            SSN: SSON_3797(gpsA)
            SBO: SBO_3614(gpsA)
            SBC: SbBS512_E4036(gpsA)
            SDY: SDY_4041(gpsA)
            ECA: ECA0173(gpsA)
            PCT: PC1_4081
            PWA: Pecwa_4362(gpsA)
            ETA: ETA_00910(gpsA)
            EPY: EpC_01020(gpsA)
            EAM: EAMY_0101(gpsA)
            EAY: EAM_0096(gpsA)
            EBI: EbC_00870(gpsA)
            PLU: plu4838(gpsA)
            PAY: PAU_04346(gpsA)
            WBR: WGLp539(gpsA)
            SGL: SG2184(gpsA)
            ENT: Ent638_0127(gpsA)
            ENC: ECL_00156
            ESC: Entcl_0135
            ESA: ESA_04119(gpsA)
            CTU: Ctu_41170(gpsA)
            KPN: KPN_03952(gpsA)
            KPE: KPK_0143(gpsA)
            KPU: KP1_5301(gpsA)
            KVA: Kvar_0149
            CKO: CKO_05065(gpsA)
            CRO: ROD_42081(gpsA)
            SPE: Spro_4815(gpsA)
            PMR: PMI3184(gpsA)
            EIC: NT01EI_3815(gpsA)
            ETR: ETAE_3457
            BFL: Bfl604(gpsA)
            BPN: BPEN_626(gpsA)
            BVA: BVAF_607(gpsA)
            DDA: Dd703_0180(gpsA)
            DDC: Dd586_0171
            DDD: Dda3937_02048(gpsA)
            DZE: Dd1591_3939(gpsA)
            XBO: XBJ1_4331(gpsA)
            XNE: XNC1_0141(gpsA)
            PAM: PANA_3878(gpsA)
            PVA: Pvag_3171(gpsA)
            PAO: Pat9b_3885
            HIN: HI0605(gpsA)
            HIT: NTHI0860(gpsA)
            HIP: CGSHiEE_02000(gpsA)
            HIF: HIBPF16050
            HIL: HICON_06930
            HDU: HD0660(gpsA)
            HAP: HAPS_1513(gpsA)
            HSO: HS_0155(gpsA)
            HSM: HSM_0021(gpsA)
            PMU: PM1431(gpsA)
            MSU: MS2213(gpsA)
            APL: APL_1510(gpsA)
            APJ: APJL_1536(gpsA)
            APA: APP7_1570(gpsA)
            ASU: Asuc_0385
            AAP: NT05HA_1985
            AAT: D11S_0306
            XFA: XF1802(gpsA)
            XFT: PD1064(gpsA)
            XFM: Xfasm12_1221(gpsA)
            XFN: XfasM23_1129(gpsA)
            XCC: XCC0204(gpsA)
            XCB: XC_0214(gpsA)
            XCA: xccb100_0225(gpsA)
            XCV: XCV0207(gpsA)
            XAC: XAC0222(gpsA)
            XOO: XOO4198(gpsA)
            XOM: XOO_3967(gpsA)
            XOP: PXO_03969(gpsA)
            XAL: XALc_3078(gpsA)
            SML: Smlt0172(gpsA)
            SMT: Smal_0136(gpsA)
            PSU: Psesu_0106
            VCH: VC2651(gpsA)
            VCO: VC0395_A2226(gpsA)
            VCM: VCM66_2571(gpsA)
            VCJ: VCD_001714(gpsA)
            VVU: VV1_1277(gpsA)
            VVY: VV3087(gpsA)
            VVM: VVM_00435
            VPA: VP2832(gpsA)
            VHA: VIBHAR_00124(gpsA)
            VSP: VS_0205(gpsA)
            VEX: VEA_002244
            VFI: VF_2348(gpsA)
            VFM: VFMJ11_2469(gpsA)
            VSA: VSAL_I2801(gpsA)
            PPR: PBPRA0227(gpsA)
            PAE: PA1614(gpsA)
            PAU: PA14_43640(gpsA)
            PAP: PSPA7_3659(gpsA)
            PAG: PLES_37131(gpsA)
            PPU: PP_4169(gpsA)
            PPF: Pput_1698(gpsA)
            PPG: PputGB1_3741(gpsA)
            PPW: PputW619_3493(gpsA)
            PST: PSPTO_2213(gpsA)
            PSB: Psyr_2022(gpsA)
            PSP: PSPPH_1994(gpsA)
            PFL: PFL_1741(gpsA)
            PFO: Pfl01_4208(gpsA)
            PFS: PFLU1840(gpsA)
            PEN: PSEEN3618(gpsA)
            PMY: Pmen_2467(gpsA)
            PSA: PST_1894(gpsA)
            CJA: CJA_1957(gpsA)
            AVN: Avin_29030(gpsA)
            PAR: Psyc_1286(gpsA)
            PCR: Pcryo_1096(gpsA)
            PRW: PsycPRwf_0931(gpsA)
            ACI: ACIAD1317(gpsA)
            ACD: AOLE_05765(gpsA)
            ACB: A1S_2257(gpsA)
            ABM: ABSDF1271(gpsA)
            ABY: ABAYE1223(gpsA)
            ABC: ACICU_02458(gpsA)
            ABN: AB57_2614(gpsA)
            ABB: ABBFA_001183(gpsA)
            MCT: MCR_0836(gpsA)
            SON: SO_0053(gpsA)
            SDN: Sden_3695(gpsA)
            SFR: Sfri_4018(gpsA)
            SAZ: Sama_0063(gpsA)
            SBL: Sbal_4329(gpsA)
            SBM: Shew185_0046(gpsA)
            SBN: Sbal195_0050(gpsA)
            SBP: Sbal223_0050(gpsA)
            SLO: Shew_3803(gpsA)
            SPC: Sputcn32_0043(gpsA)
            SSE: Ssed_4467(gpsA)
            SPL: Spea_4214(gpsA)
            SHE: Shewmr4_0048(gpsA)
            SHM: Shewmr7_0046(gpsA)
            SHN: Shewana3_0054(gpsA)
            SHW: Sputw3181_4035(gpsA)
            SHL: Shal_0046(gpsA)
            SWD: Swoo_4874(gpsA)
            SWP: swp_0081(gpsA)
            SVO: SVI_4303(gpsA)
            ILO: IL0236(gpsA)
            CPS: CPS_4387(gpsA)
            PHA: PSHAa0370(gpsA)
            PAT: Patl_3615
            PSM: PSM_A2721(gpsA)
            SDE: Sde_2098(gpsA)
            MAQ: Maqu_1477(gpsA)
            AMC: MADE_00540
            PIN: Ping_3207
            TTU: TERTU_2515(gpsA)
            FBL: Fbal_3753
            CBU: CBU_1518(gpsA)
            CBS: COXBURSA331_A1701(gpsA)
            CBD: CBUD_0466(gpsA)
            CBG: CbuG_0491(gpsA)
            CBC: CbuK_1746(gpsA)
            LPN: lpg2309(gpsA)
            LPF: lpl2228(gpsA)
            LPP: lpp2257(gpsA)
            LPC: LPC_1774(gpsA)
            LPA: lpa_03310(gpsA)
            LLO: LLO_0575(gpsA)
            MCA: MCA2538(gpsA)
            FTU: FTT_0871(gpsA)
            FTF: FTF0871(gpsA)
            FTW: FTW_1309(gpsA)
            FTL: FTL_0372(gpsA)
            FTH: FTH_0365(gpsA)
            FTA: FTA_0395(gpsA)
            FTM: FTM_0460(gpsA)
            FTN: FTN_0397(gpsA)
            FPH: Fphi_0440(gpsA)
            TCX: Tcr_1952
            NOC: Noc_0035(gpsA)
            NHL: Nhal_0027
            NWA: Nwat_0033
            ALV: Alvin_3030
            AEH: Mlg_2572(gpsA)
            HHA: Hhal_1214(gpsA)
            TGR: Tgr7_3281(gpsA)
            TKM: TK90_2026
            HNA: Hneap_2345
            HCH: HCH_02763(gpsA)
            CSA: Csal_2490(gpsA)
            HEL: HELO_3421(gpsA)
            ABO: ABO_1488(gpsA)
            KKO: Kkor_2293
            MMW: Mmwyl1_2121
            AHA: AHA_0296(gpsA)
            ASA: ASA_4101(gpsA)
            TAU: Tola_0509(gpsA)
            DNO: DNO_0293
            AFE: Lferr_1785(gpsA)
            AFR: AFE_2126(gpsA)
            BCI: BCI_0173(gpsA)
            RMA: Rmag_0934(gpsA)
            VOK: COSY_0840(gpsA)
            GPB: HDN1F_15890(gpsA)
            NMA: NMA0375(gpsA)
            NME: NMB2060(gpsA)
            NMC: NMC2041(gpsA)
            NMN: NMCC_0126(gpsA)
            NMI: NMO_0107(gpsA)
            NGO: NGO2021(gpsA)
            NGK: NGK_2215(gpsA)
            NLA: NLA_2630(gpsA)
            CVI: CV_1129(gpsA)
            LHK: LHK_02840(gpsA)
            RSO: RSc0357(gpsA)
            RSC: RCFBP_21130(gpsA)
            RSL: RPSI07_3052(gpsA)
            RPI: Rpic_0213(gpsA)
            RPF: Rpic12D_0232(gpsA)
            REU: Reut_A0308(gpsA)
            REH: H16_A0336(gpsA)
            RME: Rmet_0255(gpsA)
            CTI: RALTA_A0280(gpsA)
            BMA: BMA3204(gpsA)
            BMV: BMASAVP1_A0177(gpsA)
            BML: BMA10229_A1415(gpsA)
            BMN: BMA10247_2842(gpsA)
            BPS: BPSL0447(gpsA)
            BPM: BURPS1710b_0666(gpsA)
            BPL: BURPS1106A_0501(gpsA)
            BPD: BURPS668_0482(gpsA)
            BPR: GBP346_A0411(gpsA)
            BTE: BTH_I0420(gpsA)
            BVI: Bcep1808_2953(gpsA)
            BUR: Bcep18194_A6182(gpsA)
            BCN: Bcen_2239(gpsA)
            BCH: Bcen2424_2853(gpsA)
            BCM: Bcenmc03_2864(gpsA)
            BCJ: BCAL0743(gpsA)
            BAM: Bamb_2908(gpsA)
            BAC: BamMC406_2770(gpsA)
            BMU: Bmul_0450(gpsA)
            BMJ: BMULJ_02805(gpsA)
            BXE: Bxe_A4177(gpsA)
            BPH: Bphy_0270(gpsA)
            BPY: Bphyt_0538(gpsA)
            BGL: bglu_1g31750(gpsA)
            BGE: BC1002_0264
            BRH: RBRH_02191
            PNU: Pnuc_1944(gpsA)
            PNE: Pnec_1649(gpsA)
            BPE: BP0603(gpsA)
            BPA: BPP0291(gpsA)
            BBR: BB0294(gpsA)
            BPT: Bpet4698(gpsA)
            BAV: BAV0239(gpsA)
            AXY: AXYL_06074(gpsA)
            TEQ: TEQUI_0741
            RFR: Rfer_1313(gpsA)
            POL: Bpro_0890(gpsA)
            PNA: Pnap_0931(gpsA)
            AAV: Aave_3854(gpsA)
            AJS: Ajs_3501(gpsA)
            DIA: Dtpsy_2824(gpsA)
            VEI: Veis_0042(gpsA)
            DAC: Daci_1817(gpsA)
            VAP: Vapar_4099(gpsA)
            VPE: Varpa_4766
            CTT: CtCNB1_3885
            ADN: Alide_3434
            MPT: Mpe_A0717(gpsA)
            HAR: HEAR2970(gpsA)
            MMS: mma_3217(gpsA)
            HSE: Hsero_0158(gpsA)
            LCH: Lcho_3814(gpsA)
            TIN: Tint_0740 Tint_2685
            NEU: NE2208(gpsA)
            NET: Neut_0660(gpsA)
            NMU: Nmul_A1126(gpsA)
            EBA: ebA1060(gpsA)
            AZO: azo2814(gpsA)
            DAR: Daro_0615(gpsA)
            TMZ: Tmz1t_1539(gpsA)
            TBD: Tbd_2404(gpsA)
            MFA: Mfla_2183
            MMB: Mmol_0569
            MEH: M301_0575
            MEI: Msip34_0556
            MEP: MPQ_0581(gpsA)
            APP: CAP2UW1_1510(gpsA)
            SLT: Slit_2610
            GCA: Galf_0224
            HPY: HP0961(gpsA)
            HPJ: jhp0895(gpsA)
            HPA: HPAG1_0945(gpsA)
            HPS: HPSH_05065(gpsA)
            HPG: HPG27_909(gpsA)
            HPP: HPP12_0957(gpsA)
            HPB: HELPY_0947(gpsA)
            HPL: HPB8_584(gpsA)
            HPC: HPPC_04855(gpsA)
            HPM: HPSJM_04900(gpsA)
            HHE: HH0794(gpsA)
            HAC: Hac_1037(gpsA)
            HMS: HMU01880(gpsA)
            HFE: Hfelis_09620(gpsA)
            WSU: WS2004(gpsA)
            TDN: Suden_1330(gpsA)
            SKU: Sulku_0825
            CJE: Cj1196c(gpsA)
            CJR: CJE1330(gpsA)
            CJJ: CJJ81176_1211(gpsA)
            CJU: C8J_1140(gpsA)
            CJN: ICDCCJ_1147
            CJD: JJD26997_0533(gpsA)
            CFF: CFF8240_0775(gpsA)
            CCV: CCV52592_0792(gpsA)
            CHA: CHAB381_0943(gpsA)
            CLA: Cla_1206(gpsA)
            ABU: Abu_0029(gpsA)
            ANT: Arnit_0116
            SDL: Sdel_1130
            NIS: NIS_0859(gpsA)
            SUN: SUN_1577(gpsA)
            NSA: Nitsa_0710
            NAM: NAMH_1088(gpsA)
            GSU: GSU0006(gpsA)
            GME: Gmet_0008(gpsA)
            GUR: Gura_0007(gpsA)
            GLO: Glov_0029
            GBM: Gbem_0008(gpsA)
            GEO: Geob_0007(gpsA)
            GEM: GM21_0007(gpsA)
            PCA: Pcar_0007(gpsA)
            PPD: Ppro_0007
            DVU: DVU3159(gpsA)
            DVL: Dvul_0226(gpsA)
            DDE: Dde_3178(gpsA)
            DDS: Ddes_1879
            DMA: DMR_11830(gpsA)
            DSA: Desal_0748
            DAS: Daes_0751
            LIP: LI0828(gpsA)
            DBA: Dbac_3001
            DRT: Dret_2423
            DPS: DP0651
            DAK: DaAHT2_2105
            DPR: Despr_3293
            DOL: Dole_0674
            DAL: Dalk_0486
            DAT: HRM2_11980(gpsA2)
            ADE: Adeh_0396(gpsA)
            ACP: A2cp1_0425(gpsA)
            AFW: Anae109_4181(gpsA)
            ANK: AnaeK_0424(gpsA)
            MXA: MXAN_1354(gpsA)
            SCL: sce7273(gpsA1)
            HOH: Hoch_4050
            SAT: SYN_01987
            SFU: Sfum_2691
            DBR: Deba_0262
            RPR: RP442(gpsA)
            RTY: RT0429(gpsA)
            RCO: RC0615(gpsA)
            RFE: RF_0677(gpsA)
            RAK: A1C_03310(gpsA)
            RRI: A1G_03470(gpsA)
            RRJ: RrIowa_0734
            RMS: RMA_0628(gpsA)
            RAF: RAF_ORF0573(gpsA)
            RBE: RBE_1225(gpsA)
            RBO: A1I_01190(gpsA)
            OTS: OTBS_1307(gpsA)
            OTT: OTT_1001(gpsA)
            WOL: WD0731(gpsA)
            WBM: Wbm0597
            WRI: WRi_007450(gpsA)
            WPI: WPa_0584(gpsA)
            AMA: AM985(gpsA)
            AMF: AMF_753(gpsA)
            ACN: ACIS_00355(gpsA)
            APH: APH_0198(gpsA)
            ERU: Erum6600(gpsA)
            ERW: ERWE_CDS_06920(gpsA)
            ERG: ERGA_CDS_06830(gpsA)
            ECN: Ecaj_0667
            ECH: ECH_0340(gpsA)
            NSE: NSE_0228(gpsA)
            NRI: NRI_0220
            PUB: SAR11_1295(gpsA)
            MLO: mlr4225(gpsA)
            MCI: Mesci_1047
            MES: Meso_3204(gpsA)
            PLA: Plav_1343
            SME: SMc03229(gpsA)
            SMD: Smed_2692 Smed_2964(gpsA)
            RHI: NGR_c32130(gpsA)
            ATU: Atu2650(gpsA)
            ARA: Arad_4354(gpsA)
            AVI: Avi_4143(gpsA)
            RET: RHE_CH03902(gpsA) RHE_PA00028(ypa00009)
            REC: RHECIAT_CH0004186(gpsA)
            RLE: RL4493(gpsA)
            RLT: Rleg2_3697(gpsA)
            RLG: Rleg_4018(gpsA)
            LAS: CLIBASIA_04705(gpsA)
            LSO: CKC_03150
            BME: BMEI0174(gpsA)
            BMI: BMEA_A1942
            BMF: BAB1_1889(gpsA)
            BMB: BruAb1_1866(gpsA)
            BMC: BAbS19_I17710(gpsA)
            BMS: BR1889(gpsA)
            BMT: BSUIS_A1729(gpsA)
            BOV: BOV_1817(gpsA)
            BCS: BCAN_A1932(gpsA)
            BMR: BMI_I1910(gpsA)
            OAN: Oant_0973(gpsA)
            BJA: blr0568(gpsA)
            BRA: BRADO0303(gpsA)
            BBT: BBta_0290(gpsA)
            RPA: RPA0254(gpsA)
            RPB: RPB_0316(gpsA)
            RPC: RPC_0045(gpsA)
            RPD: RPD_0471(gpsA)
            RPE: RPE_0066(gpsA)
            RPT: Rpal_0255(gpsA)
            RPX: Rpdx1_0380
            NWI: Nwi_0469(gpsA)
            NHA: Nham_0560(gpsA)
            OCA: OCAR_4328
            BHE: BH01260(gpsA)
            BQU: BQ01190(gpsA)
            BBK: BARBAKC583_1191(gpsA)
            BTR: Btr_0137(gpsA)
            BGR: Bgr_01240(gpsA)
            XAU: Xaut_1156(gpsA)
            AZC: AZC_0263(gpsA)
            SNO: Snov_2808
            MEX: Mext_0730(gpsA)
            MEA: Mex_1p0556(gpsA)
            MDI: METDI0832(gpsA)
            MRD: Mrad2831_1746(gpsA)
            MET: M446_4531(gpsA)
            MPO: Mpop_0703(gpsA)
            MCH: Mchl_0743(gpsA)
            MNO: Mnod_4465(gpsA)
            BID: Bind_3219(gpsA)
            MSL: Msil_0925(gpsA)
            HDN: Hden_3452
            RVA: Rvan_2215
            CCR: CC_0070(gpsA)
            CCS: CCNA_00068(gpsA)
            CAK: Caul_0116(gpsA)
            CSE: Cseg_0061
            PZU: PHZ_c3407(gpsA)
            BSB: Bresu_0411
            AEX: Astex_0747
            SIL: SPO3855(gpsA)
            SIT: TM1040_2830(gpsA)
            RSP: RSP_1510(gpsA)
            RSH: Rsph17029_0162(gpsA)
            RSQ: Rsph17025_2915(gpsA)
            RSK: RSKD131_2903(gpsA)
            RCP: RCAP_rcc03507(gpsA)
            JAN: Jann_4079(gpsA)
            RDE: RD1_0469(gpsA)
            PDE: Pden_1999(gpsA)
            DSH: Dshi_3414(gpsA) Dshi_3830
            KVU: EIO_2682(gpsA)
            MMR: Mmar10_0038(gpsA)
            HNE: HNE_0982(gpsA)
            HBA: Hbal_0075
            ZMO: ZMO1905
            ZMN: Za10_1238
            NAR: Saro_2784(gpsA)
            SAL: Sala_0199(gpsA) Sala_2874(gpsA)
            SWI: Swit_1932(gpsA)
            SJP: SJA_C1-03140(gpsA)
            ELI: ELI_09165(gpsA)
            GOX: GOX1880(gpsA)
            GBE: GbCGDNIH1_2427
            ACR: Acry_1484
            GDI: GDI_2073(gpsA)
            GDJ: Gdia_0294(gpsA)
            APT: APA01_04490
            RRU: Rru_A3571(gpsA)
            RCE: RC1_2361(gpsA)
            MAG: amb4006
            AZL: AZL_004060(gpsA)
            PBR: PB2503_03002
            APB: SAR116_1477
            MGM: Mmc1_0741
            DIN: Selin_1822
            BSU: BSU22830(gpsA)
            BSS: BSUW23_11200(gpsA)
            BHA: BH1640(gpsA)
            BAN: BA_1526(gpsA)
            BAR: GBAA_1526(gpsA)
            BAT: BAS1415(gpsA)
            BAH: BAMEG_3067(gpsA)
            BAI: BAA_1595(gpsA)
            BAL: BACI_c15480(gpsA)
            BCE: BC1505(gpsA)
            BCA: BCE_1632(gpsA)
            BCZ: BCZK1387(gpsA)
            BCR: BCAH187_A1668(gpsA)
            BCB: BCB4264_A1560(gpsA)
            BCU: BCAH820_1599(gpsA)
            BCG: BCG9842_B3784(gpsA)
            BCQ: BCQ_1574(gpsA)
            BCX: BCA_1564(gpsA)
            BCY: Bcer98_1228(gpsA)
            BTK: BT9727_1387(gpsA)
            BTL: BALH_1360(gpsA)
            BTB: BMB171_C1338(gpsA)
            BWE: BcerKBAB4_1429(gpsA)
            BLI: BL02791(gpsA)
            BLD: BLi02420(gpsA)
            BAY: RBAM_020990(gpsA)
            BAO: BAMF_2184(gpsA)
            BAE: BATR1942_09285(gpsA)
            BCL: ABC1878(gpsA)
            BPU: BPUM_2014(gpsA)
            BPF: BpOF4_15365(gpsA)
            BMQ: BMQ_4338(gpsA)
            BMD: BMD_4324(gpsA)
            BSE: Bsel_2142
            BCO: Bcell_1857
            OIH: OB1796(gpsA)
            GKA: GK2220(gpsA)
            GTN: GTNG_2153(gpsA)
            GWC: GWCH70_2158(gpsA)
            GYM: GYMC10_2186
            GYC: GYMC61_0461(gpsA)
            GYA: GYMC52_2201
            GCT: GC56T3_1283
            GMC: GY4MC1_1341
            AFL: Aflv_1086(gpsA)
            SAU: SA1306(gpsA)
            SAV: SAV1474(gpsA)
            SAW: SAHV_1462(gpsA)
            SAH: SaurJH1_1561(gpsA)
            SAJ: SaurJH9_1531(gpsA)
            SAM: MW1363(gpsA)
            SAS: SAS1415(gpsA)
            SAR: SAR1483(gpsA)
            SAC: SACOL1514(gpsA)
            SAX: USA300HOU_1411(gpsA)
            SAA: SAUSA300_1363(gpsA)
            SAO: SAOUHSC_01491(gpsA)
            SAE: NWMN_1383(gpsA)
            SAD: SAAV_1461(gpsA)
            SAB: SAB1336c(gpsA)
            SEP: SE1162
            SER: SERP1042(gpsA)
            SHA: SH1437(gpsA)
            SSP: SSP1272(gpsA)
            SCA: Sca_1106(gpsA)
            SLG: SLGD_01433
            SSD: SPSINT_1175
            LMO: lmo1936(gpsA)
            LMF: LMOf2365_1965(gpsA)
            LMH: LMHCC_0620(gpsA)
            LMC: Lm4b_01953(gpsA)
            LMN: LM5578_2137(gpsA)
            LMY: LM5923_2088(gpsA)
            LIN: lin2050(gpsA)
            LWE: lwe1962(gpsA)
            LSG: lse_1922(gpsA)
            LSP: Bsph_1921
            ESI: Exig_1804
            EAT: EAT1b_2989
            MCL: MCCL_1125(glyC)
            BBE: BBR47_24500(gpsA)
            PJD: Pjdr2_2392
            PPY: PPE_02766
            PPM: PPSC2_c3140
            AAC: Aaci_1699
            BTS: Btus_1767
            LLA: L0016(gpsA)
            LLK: LLKF_1429(gpsA)
            LLC: LACR_1461(gpsA)
            LLM: llmg_1114(gpsA)
            SPY: SPy_0226(gpsA)
            SPZ: M5005_Spy_0194(gpsA)
            SPM: spyM18_0212(gpsA)
            SPG: SpyM3_0161(gpsA)
            SPS: SPs0167(gpsA)
            SPH: MGAS10270_Spy0193(gpsA)
            SPI: MGAS10750_Spy0189(gpsA)
            SPJ: MGAS2096_Spy0206(gpsA)
            SPK: MGAS9429_Spy0195(gpsA)
            SPF: SpyM50173(gpsA)
            SPA: M6_Spy0225(gpsA)
            SPB: M28_Spy0188(gpsA)
            SOZ: Spy49_0192c(gpsA)
            SPN: SP_2091(gpsA)
            SPD: SPD_1918(gpsA)
            SPR: spr1902(gpsA)
            SPW: SPCG_2057(gpsA)
            SPX: SPG_2029(gpsA)
            SNE: SPN23F_21160(gpsA)
            SPV: SPH_2278(gpsA)
            SNM: SP70585_2197(gpsA)
            SJJ: SPJ_2112(gpsA)
            SPP: SPP_2146(gpsA)
            SNT: SPT_2101(gpsA)
            SNC: HMPREF0837_10088(gpsA)
            SNB: SP670_2231
            SNP: SPAP_2137
            SAG: SAG0407(gpsA)
            SAN: gbs0442(gpsA)
            SAK: SAK_0480(gpsA)
            SMU: SMU.323(gpsA)
            SMC: SmuNN2025_1626(gbpS)
            STC: str1832(gpsA)
            STL: stu1832(gpsA)
            STE: STER_1809(gpsA)
            SSA: SSA_2168(gpsA)
            SSU: SSU05_2040(gpsA)
            SSV: SSU98_2040(gpsA)
            SSB: SSUBM407_1897(gpsA)
            SSI: SSU1827(gpsA)
            SSS: SSUSC84_1849(gpsA)
            SGO: SGO_0164(gpsA)
            SEQ: SZO_17500(gpsA)
            SEZ: Sez_0217(gpsA)
            SEU: SEQ_0290(gpsA)
            SUB: SUB1691(gpsA)
            SDS: SDEG_1979(gpsA)
            SGA: GALLO_2092(gpdA)
            SMB: smi_0148(gpdA)
            LPL: lp_0756(gpsA)
            LPJ: JDM1_0625(gpsA)
            LPS: LPST_C0580(gpsA)
            LJO: LJ0851(gpsA)
            LJF: FI9785_1352(gpsA)
            LAC: LBA0678(gpsA)
            LSA: LSA0518(gpsA)
            LSL: LSL_0372(gpsA)
            LDB: Ldb0612(gpsA) Ldb1959(gpsA)
            LBU: LBUL_0547(gpsA) LBUL_1823(gpsA)
            LDE: LDBND_0554(gpsA) LDBND_1802(gpsA)
            LBR: LVIS_0643
            LCA: LSEI_0947(gpsA)
            LCB: LCABL_10610(gpsA)
            LCZ: LCAZH_0890
            LGA: LGAS_1326(gpsA)
            LRE: Lreu_0371(gpsA)
            LRF: LAR_0360(gpsA)
            LHE: lhv_0725(gpsA)
            LFE: LAF_0339(gpsA)
            LRH: LGG_00919(gpsA)
            LRL: LC705_00967(gpsA)
            LCR: LCRIS_00687(gpsA)
            LAM: LA2_03495(gpsA)
            PPE: PEPE_0443(gpsA)
            EFA: EF1747(gpsA)
            OOE: OEOE_0564
            LME: LEUM_0598(gpsA)
            LCI: LCK_01252(gpsA)
            LKI: LKI_08350(gpsA)
            LGS: LEGAS_0660(gpsA)
            CAC: CA_C1712(gpsA)
            CPE: CPE1754(gpsA)
            CPF: CPF_2007(gpsA)
            CPR: CPR_1725(gpsA)
            CTC: CTC01139(gpsA)
            CTH: Cthe_1022
            CDF: CD2630(glyC)
            CDC: CD196_2471(glyC)
            CDL: CDR20291_2518(glyC)
            CBO: CBO2518(gpsA)
            CBA: CLB_2395(gpsA)
            CBH: CLC_2377(gpsA)
            CBY: CLM_2823(gpsA)
            CBL: CLK_1902(gpsA)
            CBK: CLL_A1204(gpsA)
            CBB: CLD_2117(gpsA)
            CBI: CLJ_B2749(gpsA)
            CBT: CLH_1155(gpsA)
            CBF: CLI_2581(gpsA)
            CBE: Cbei_1135(gpsA) Cbei_2503
            CKL: CKL_1357(gpsA)
            CKR: CKR_1253(gpsA)
            CPY: Cphy_2388(gpsA) Cphy_3205
            CCE: Ccel_2129
            CLJ: CLJU_c12480
            CSH: Closa_2095
            CCB: Clocel_3207
            CST: CLOST_1883(gpsA)
            AMT: Amet_2855
            AOE: Clos_1401
            STH: STH1681
            SWO: Swol_1323
            SLP: Slip_1471
            VPR: Vpar_0834
            AFN: Acfer_1235
            DSY: DSY2249(gpsA)
            DHD: Dhaf_3379(gpsA)
            DRM: Dred_1162(gpsA)
            DAE: Dtox_2110(gpsA)
            PTH: PTH_1607(gpsA)
            DAU: Daud_1168(gpsA)
            TJR: TherJR_1580
            HMO: HM1_1987(gpsA)
            FMA: FMG_0523
            APR: Apre_0918
            EEL: EUBELI_01038(gpsA)
            ERE: EUBREC_2285(gpsA)
            ELM: ELI_1420 ELI_3423
            BPB: bpr_I1540(gpsA)
            EHA: Ethha_1156
            RAL: Rumal_2131
            TTE: TTE1617(gpsA)
            TEX: Teth514_1981(gpsA)
            TPD: Teth39_0841(gpsA)
            TIT: Thit_1454
            TMT: Tmath_1445
            TBO: Thebr_0863
            CHY: CHY_1917(gpsA)
            MTA: Moth_1320
            ADG: Adeg_0622(gpsA)
            TOC: Toce_0979
            TTM: Tthe_1740
            NTH: Nther_1628
            HOR: Hore_10550
            HAS: Halsa_1540
            AAR: Acear_1047
            MPU: MYPU_1240(gpsA)
            MPE: MYPE2300(gpsA)
            MGA: MGA_1133(gpsA)
            MMY: MSC_0409(gpsA)
            MMO: MMOB4820(gpsA)
            MSY: MS53_0654(gpsA)
            MCP: MCAP_0576(gpsA)
            MAA: MAG_0500(gpsA)
            MAL: MAGa0530(gpsA)
            MAT: MARTH_orf305(gpsA)
            MHO: MHO_1690(gpsA)
            MCD: MCRO_0680
            MHR: MHR_0350(gpsA)
            MFR: MFE_07190(gpsA)
            MFM: MfeM64YM_0887(gpsA)
            MBV: MBOVPG45_0057(gpsA)
            MLC: MSB_A0580
            UUR: UU382(gpsA)
            UPA: UPA3_0398
            UUE: UUR10_0425
            POY: PAM_241(gpsA)
            AYW: AYWB_480(gpsA)
            PML: ATP_00120(gpsA)
            PAL: PAa_0684(gpsA)
            ACL: ACL_0873(gpsA)
            MFL: Mfl200
            MTU: Rv0564c(gpsA) Rv2982c(gpsA)
            MTC: MT0590(gpsA) MT3060(gpsA)
            MRA: MRA_0571(gpsA1) MRA_3011(gpsA)
            MTF: TBFG_10574 TBFG_12997(gpsA)
            MTB: TBMG_00569(TBMG_00569.1) TBMG_00987(gpsA)
            MBO: Mb0579c(gpsA) Mb3006c(gpsA)
            MBB: BCG_0609c(gpdA1) BCG_3003c(gpsA)
            MBT: JTY_0579(gpdA1) JTY_2998(gpsA)
            MLE: ML1679(gpsA)
            MLB: MLBr_01679(gpsA)
            MPA: MAP3020c(gpsA) MAP4061c(gpsA)
            MAV: MAV_4577
            MSM: MSMEG_1140 MSMEG_2393(gpsA)
            MUL: MUL_0667(gpdA1) MUL_1975(gpsA)
            MVA: Mvan_0995 Mvan_2141(gpsA)
            MGI: Mflv_4221(gpsA) Mflv_5249
            MAB: MAB_3288c MAB_3915
            MMC: Mmcs_0774 Mmcs_1927(gpsA)
            MKM: Mkms_0788 Mkms_1973(gpsA)
            MJL: Mjls_0769 Mjls_1907(gpsA)
            MSP: Mspyr1_08140 Mspyr1_35640
            MMI: MMAR_0915(gpdA1) MMAR_1732(gpsA)
            CGL: NCgl1266(gpsA)
            CGB: cg1492(gpsA)
            CGT: cgR_1394(gpsA)
            CEF: CE1430(gpsA)
            CDI: DIP1130(gpsA)
            CJK: jk0920(gpsA2) jk1218(gpsA)
            CUR: cur_0777(gpsA)
            CAR: cauri_1159(gpsA)
            CKP: ckrop_1209(gpsA)
            CPU: cpfrc_00914(gpsA)
            NFA: nfa42060(gpsA)
            RHA: RHA1_ro02396(gpsA) RHA1_ro06505(gpsA)
            RER: RER_24140(gpsA) RER_53170(gpsA)
            ROP: ROP_21080(gpsA) ROP_65560(gpsA)
            REQ: REQ_31290(gpdA2) REQ_44820
            GBR: Gbro_3209
            TPR: Tpau_2842
            SRT: Srot_0989
            SCO: SCO5559(gpsA)
            SMA: SAV_2680(gpsA)
            SGR: SGR_1922(gpsA)
            SCB: SCAB_26541(gpdA)
            TWH: TWT506(gpsA)
            TWS: TW256(gpsA)
            LXX: Lxx09700(gpsA)
            CMI: CMM_1345(gpsA)
            CMS: CMS_2048(gpsA)
            ART: Arth_2515
            AAU: AAur_2482
            ACH: Achl_2252
            AAI: AARI_14390(gpsA)
            RSA: RSal33209_1786
            KRH: KRH_10360(gpsA)
            MLU: Mlut_08780
            RMU: RMDY18_08120
            RDN: HMPREF0733_12142(gpsA)
            BCV: Bcav_1590
            BFA: Bfae_18510 Bfae_27910
            JDE: Jden_1682
            KSE: Ksed_10760
            XCE: Xcel_2292
            SKE: Sked_11140
            CFL: Cfla_2312
            ICA: Intca_2325
            PAC: PPA2315
            PAK: HMPREF0675_5393
            PFR: PFREUD_00770(gpsA)
            NCA: Noca_3293
            KFL: Kfla_4851
            TFU: Tfu_0631(gpsA)
            NDA: Ndas_0190
            TCU: Tcur_3456
            SRO: Sros_8010
            FRA: Francci3_3614(gpsA)
            FRE: Franean1_1123(gpsA)
            FRI: FraEuI1c_1044
            FAL: FRAAL5821(gpsA)
            ACE: Acel_1587(gpsA)
            NML: Namu_0208 Namu_1484
            GOB: Gobs_4047
            KRA: Krad_1615
            SEN: SACE_6137(gpdA2)
            SVI: Svir_09130
            TBI: Tbis_2793
            AMD: AMED_1731(gpsA)
            AMI: Amir_5998
            STP: Strop_1266
            SAQ: Sare_1157
            MAU: Micau_1337
            MIL: ML5_1583
            CAI: Caci_8043(gpsA)
            SNA: Snas_4989
            MCU: HMPREF0573_10501(gpsA)
            BLO: BL0346(gpsA)
            BLJ: BLD_1113(gpsA)
            BLN: Blon_0319(gpsA)
            BLL: BLJ_0286(gpsA)
            BLB: BBMN68_1108(gpsA)
            BAD: BAD_0185(gpsA)
            BLA: BLA_0235(gpsA)
            BLC: Balac_0247(gpsA)
            BLT: Balat_0247(gpsA)
            BDE: BDP_0282(gpsA)
            BBI: BBIF_0282(gpsA)
            BBP: BBPR_0261(gpsA)
            GVA: HMPREF0424_1234
            GVG: HMPREF0421_20312(gpsA)
            CWO: Cwoe_5566
            CCU: Ccur_06910
            SHI: Shel_09720
            APV: Apar_0730
            ELE: Elen_1339
            OLS: Olsu_0920
            CTR: CT714(gpsA)
            CTA: CTA_0776(gpsA)
            CTB: CTL0083(gpsA)
            CTL: CTLon_0083(gpsA)
            CTJ: JALI_7191(gpsA)
            CTZ: CTB_7191(gpsA)
            CMU: TC0087(gpsA)
            CPN: CPn0855(gpsA)
            CPA: CP1014(gpsA)
            CPJ: CPj0855(gpsA)
            CPT: CpB0884(gpsA)
            CCA: CCA00912(gpsA)
            CAB: CAB880(gpsA)
            CFE: CF0102(gpsA)
            PCU: pc0083(gpsA)
            WCH: wcw_1793(gpdA)
            BBU: BB0368(gpsA)
            BBZ: BbuZS7_0370(gpsA)
            BGA: BG0367(gpsA)
            BAF: BAPKO_0377(gpsA)
            BTU: BT0368(gpsA)
            BHR: BH0368(gpsA)
            BDU: BDU_363(gpsA)
            BRE: BRE_367(gpsA)
            TPA: TP1009(gpsA)
            TPP: TPASS_1009(gpsA)
            TDE: TDE2090(gpsA)
            SSM: Spirs_0873
            LIL: LA_3939(gpsA)
            LIC: LIC13145(gpsA)
            LBJ: LBJ_0395(gpsA)
            LBL: LBL_2682(gpsA)
            LBI: LEPBI_I0227 LEPBI_I0345(gpsA)
            LBF: LBF_0334(gpsA)
            BHY: BHWA1_00500(gspA)
            BRM: Bmur_0080
            BPO: BP951000_0337(gspA)
            ABA: Acid345_2137(gpsA)
            ACA: ACP_3411(gpsA)
            TSA: AciPR4_3138
            SUS: Acid_0313(gpsA)
            BTH: BT_2123
            BFR: BF3811
            BFS: BF3603
            BVU: BVU_4108
            BHL: Bache_3339
            PGI: PG1369(gpsA)
            PGN: PGN_1156
            PDI: BDI_0149
            PPN: Palpr_3046
            APS: CFPG_625
            PRU: PRU_1692
            PMZ: HMPREF0659_A6045
            SRU: SRU_1473(gpsA) SRU_1481(gpsA)
            SRM: SRM_01666(gpsA) SRM_01674(gpsA)
            RMR: Rmar_1270
            CHU: CHU_1307(gpsA)
            DFE: Dfer_2864
            SLI: Slin_1206
            LBY: Lbys_2041
            MTT: Ftrac_3756
            CPI: Cpin_0966
            PHE: Phep_0664
            GFO: GFO_3429(gpsA)
            FJO: Fjoh_0762
            FPS: FP0141(gpsA)
            COC: Coch_0393
            RBI: RB2501_07725
            ZPR: ZPR_0332
            CAT: CA2559_02220
            RAN: Riean_1586
            FBC: FB2170_06890
            CAO: Celal_1220
            FBA: FIC_01622
            AAS: Aasi_0284
            FSU: Fisuc_2248
            FNU: FN0906(gpsA)
            LBA: Lebu_1269
            STR: Sterm_2000
            SMF: Smon_0576
            IPO: Ilyop_1275
            OTE: Oter_2230
            CAA: Caka_2245
            MIN: Minf_0182(gpsA)
            AMU: Amuc_0795
            GAU: GAU_1603(gpsA)
            PLM: Plim_1353
            IPA: Isop_0834
            EMI: Emin_1110
            RSD: TGRD_142
            TAI: Taci_0259
            ACO: Amico_1622
            SYN: slr1755(gpsA)
            SYF: Synpcc7942_2522
            SYR: SynRCC307_1214
            SYP: SYNPCC7002_A2853(gpsA)
            CYA: CYA_0480
            CYB: CYB_0350
            TEL: tll2111
            MAR: MAE_31130
            CYT: cce_4760(gpsA)
            CYP: PCC8801_4137
            CYC: PCC7424_1190
            CYN: Cyan7425_2777
            CYH: Cyan8802_4177
            CYJ: Cyan7822_4200
            GVI: gvip496(glpD)
            ANA: all1693
            NPU: Npun_F0995
            AVA: Ava_1163
            NAZ: Aazo_0566
            TER: Tery_1811
            AMR: AM1_4768
            CTE: CT0092(gpsA)
            CPC: Cpar_2000(gpsA)
            CCH: Cag_2026(gpsA)
            CPH: Cpha266_2580(gpsA)
            CPB: Cphamn1_2442(gpsA)
            CLI: Clim_2416(gpsA)
            PVI: Cvib_1699(gpsA)
            PLT: Plut_2057(gpsA)
            PPH: Ppha_2815(gpsA)
            PAA: Paes_2174(gpsA)
            CTS: Ctha_0029(gpsA)
            DET: DET1397(gpsA)
            DEH: cbdb_A1356(gpsA)
            DEB: DehaBAV1_1206(gpsA)
            DEV: DhcVS_1179(gpsA)
            DEG: DehalGT_1115
            DLY: Dehly_0112
            HAU: Haur_3883
            DRA: DR_2621
            DGE: Dgeo_2043
            DDR: Deide_04670(gpsA)
            DMR: Deima_0575
            TRA: Trad_0577
            TTH: TTC1378
            TTJ: TTHA1740
            TSC: TSC_c03670(gpsA)
            MRB: Mrub_2574
            MSV: Mesil_2710
            OPR: Ocepr_1426
            AAE: aq_1634(gspA)
            HYA: HY04AAS1_1158
            HTH: HTH_0831(gpsA)
            TAL: Thal_0118
            SUL: SYO3AOP1_1528
            SAF: SULAZ_0014
            PMX: PERMA_1482
            TAM: Theam_0686
            TMA: TM0378(gpsA)
            TPT: Tpet_0529
            TLE: Tlet_0002
            TRQ: TRQ2_0543
            TNA: CTN_0318
            TNP: Tnap_0183
            TME: Tmel_1790
            TAF: THA_78
            FNO: Fnod_1014
            PMO: Pmob_1386
            KOL: Kole_0002
            DTH: DICTH_1033
            DTU: Dtur_1161
            TYE: THEYE_A0581
            NDE: NIDE0531(gpsA)
            TTR: Tter_1069
            DDF: DEFDS_1969(gpsA)
            DAP: Dacet_0406
            CNI: Calni_0959
            MEM: Memar_1602
            MTH: MTH368
            MSI: Msm_1540
            MRU: mru_2188
            AFU: AF0871(gpsA)
            FPL: Ferp_1421
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.94
            IUBMB Enzyme Nomenclature: 1.1.1.94
            ExPASy - ENZYME nomenclature database: 1.1.1.94
            BRENDA, the Enzyme Database: 1.1.1.94
            CAS: 37250-30-9
///
ENTRY       EC 1.1.1.95                 Enzyme
NAME        phosphoglycerate dehydrogenase;
            D-3-phosphoglycerate:NAD+ oxidoreductase;
            alpha-phosphoglycerate dehydrogenase;
            3-phosphoglycerate dehydrogenase;
            3-phosphoglyceric acid dehydrogenase;
            D-3-phosphoglycerate dehydrogenase;
            glycerate 3-phosphate dehydrogenase;
            glycerate-1,3-phosphate dehydrogenase;
            phosphoglycerate oxidoreductase;
            phosphoglyceric acid dehydrogenase;
            SerA;
            3-phosphoglycerate:NAD+ 2-oxidoreductase;
            SerA 3PG dehydrogenase;
            3PHP reductase;
            alphaKG reductase;
            D- and L-HGA
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3-phospho-D-glycerate:NAD+ 2-oxidoreductase
REACTION    (1) 3-phospho-D-glycerate + NAD+ = 3-phosphonooxypyruvate + NADH +
            H+ [RN:R01513];
            (2) 2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+
            [RN:R08198]
ALL_REAC    R01513 R08198
SUBSTRATE   3-phospho-D-glycerate [CPD:C00197];
            NAD+ [CPD:C00003];
            2-hydroxyglutarate [CPD:C02630]
PRODUCT     3-phosphonooxypyruvate [CPD:C03232];
            NADH [CPD:C00004];
            H+ [CPD:C00080];
            2-oxoglutarate [CPD:C00026]
COMMENT     This enzyme catalyses the first committed step in the phosphoserine
            pathway of serine biosynthesis in Escherichia coli [2,3]. Reaction
            (1) occurs predominantly in the reverse direction and is inhibited
            by serine and glycine. The enzyme is unusual in that it also acts as
            a D- and L-2-hydroxyglutarate dehydrogenase (with the D-form being
            the better substrate) and as a 2-oxoglutarate reductase [3]. It has
            been postulated [3] that the cellular 2-oxoglutarate concentration
            may regulate serine biosynthesis and one-carbon metabolism directly
            by modulating the activity of this enzyme.
REFERENCE   1  [PMID:4384871]
  AUTHORS   Sugimoto E, Pizer LI.
  TITLE     The mechanism of end product inhibition of serine biosynthesis. I.
            Purification and kinetics of phosphoglycerate dehydrogenase.
  JOURNAL   J. Biol. Chem. 243 (1968) 2081-9.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   2  [PMID:14086727]
  AUTHORS   PIZER LI.
  TITLE     THE PATHWAY AND CONTROL OF SERINE BIOSYNTHESIS IN ESCHERICHIA COLI.
  JOURNAL   J. Biol. Chem. 238 (1963) 3934-44.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   3  [PMID:8550422]
  AUTHORS   Zhao G, Winkler ME.
  TITLE     A novel alpha-ketoglutarate reductase activity of the serA-encoded
            3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its
            possible implications for human 2-hydroxyglutaric aciduria.
  JOURNAL   J. Bacteriol. 178 (1996) 232-9.
  ORGANISM  Escherichia coli [GN:eco]
REFERENCE   4  [PMID:7719856]
  AUTHORS   Schuller DJ, Grant GA, Banaszak LJ.
  TITLE     The allosteric ligand site in the Vmax-type cooperative enzyme
            phosphoglycerate dehydrogenase.
  JOURNAL   Nat. Struct. Biol. 2 (1995) 69-76.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00260  Glycine, serine and threonine metabolism
            ec00680  Methane metabolism
            ec01100  Metabolic pathways
            ec01120  Microbial metabolism in diverse environments
ORTHOLOGY   K00058  D-3-phosphoglycerate dehydrogenase
GENES       HSA: 26227(PHGDH)
            PTR: 739534(PHGDH)
            PON: 100173288(PHGDH)
            MCC: 713480(PHGDH) 723360
            MMU: 236539(Phgdh)
            RNO: 58835(Phgdh)
            CFA: 607890
            AML: 100463774(PHGDH)
            BTA: 505103(PHGDH)
            SSC: 100144529(PHGDH)
            ECB: 100059940(PHGDH)
            MDO: 100012806(PHGDH)
            OAA: 100092875(PHGDH)
            GGA: 424381(PHGDH)
            XLA: 100037051(phgdh)
            XTR: 548683(phgdh)
            DRE: 321928(phgdh)
            BFO: BRAFLDRAFT_123498
            CIN: 100186739
            SPU: 590971
            DME: Dmel_CG6287
            DPO: Dpse_GA19489
            DAN: Dana_GF15130
            DER: Dere_GG10320
            DPE: Dper_GL18582
            DSE: Dsec_GM11122
            DSI: Dsim_GD22186
            DWI: Dwil_GK15239
            DYA: Dyak_GE12961
            DGR: Dgri_GH13534
            DMO: Dmoj_GI18148
            DVI: Dvir_GJ14930
            AGA: AgaP_AGAP008849
            AAG: AaeL_AAEL005336
            CQU: CpipJ_CPIJ009262
            AME: 725967
            NVI: 100116297(NV17542)
            TCA: 663218
            API: 100165735
            PHU: Phum_PHUM025750
            ISC: IscW_ISCW015967
            CEL: C31C9.2
            CBR: CBG20736
            BMY: Bm1_57055
            NVE: NEMVE_v1g170150
            HMG: 100200310
            TAD: TRIADDRAFT_37449
            ATH: AT1G17745(PGDH) AT3G19480 AT4G34200(EDA9)
            POP: POPTR_1069632 POPTR_1071977 POPTR_1084113 POPTR_1092826
                 POPTR_1110513 POPTR_201872
            RCU: RCOM_0811570 RCOM_1556820 RCOM_1589250
            VVI: 100241666 100259056 100260655
            OSA: 4337230 4341713
            SBI: SORBI_06g030920 SORBI_07g021980 SORBI_10g026070
            ZMA: 100280688(umc2594) 100280735 100281928(si707066f01) 100501398
            PPP: PHYPADRAFT_122014 PHYPADRAFT_131174
            CRE: CHLREDRAFT_136279 CHLREDRAFT_162449 CHLREDRAFT_78757(PGD1)
            VCN: VOLCADRAFT_107347 VOLCADRAFT_60404
            OLU: OSTLU_13344 OSTLU_39000
            OTA: Ot05g01370
            CME: CMC149C
            SCE: YER081W(SER3) YIL074C(SER33)
            AGO: AGOS_ACL032C
            KLA: KLLA0C09306g
            LTH: KLTH0A05038g
            PPA: PAS_chr2-1_0657
            VPO: Kpol_387p9 Kpol_411p5
            ZRO: ZYRO0C08932g
            CGR: CAGL0M12837g
            DHA: DEHA2B11000g
            PIC: PICST_87754(SER3)
            PGU: PGUG_01716
            LEL: LELG_00443
            CAL: CaO19.12728(SER3)
            CTP: CTRG_03447
            CDU: CD36_11260
            YLI: YALI0F09966g
            CLU: CLUG_03849
            NCR: NCU01439
            PAN: PODANSg2909 PODANSg8350
            MGR: MGG_07207(MG07207.4) MGG_11794
            FGR: FG07468.1 FG09483.1
            SSL: SS1G_00194 SS1G_09516
            BFU: BC1G_04899 BC1G_06095
            ANI: AN8866.2
            AFM: AFUA_1G14400 AFUA_2G04490 AFUA_4G11840 AFUA_5G05500
            NFI: NFIA_037560 NFIA_081250
            AOR: AO090009000711
            ANG: An17g02330
            AFV: AFLA_048020
            ACT: ACLA_008800
            PCS: Pc12g10550 Pc20g00530
            CIM: CIMG_01241 CIMG_06353
            CPW: CPC735_028640 CPC735_051550
            URE: UREG_01171 UREG_04045
            PNO: SNOG_09415 SNOG_13160
            TML: GSTUM_00002422001
            SPO: SPCC364.07
            CNE: CNA07520
            CNB: CNBA7340
            LBC: LACBIDRAFT_291447
            CCI: CC1G_10537
            SCM: SCHCODRAFT_64271
            UMA: UM01233.1
            MGL: MGL_1179
            MBR: MONBRDRAFT_37889
            NGR: NAEGRDRAFT_55823
            DDI: DDB_G0281071(serA)
            EHI: EHI_060860(130.t00010)
            EDI: EDI_314570
            LMA: LmjF03.0030
            LIF: LinJ20.1910
            LBZ: LbrM03_V2.0050
            TVA: TVAG_154750
            PTI: PHATRDRAFT_27166
            TPS: THAPSDRAFT_25130 THAPSDRAFT_268970
            ECO: b2913(serA)
            ECJ: JW2880(serA)
            ECD: ECDH10B_3088(serA)
            EBW: BWG_2637(serA)
            ECE: Z4251(serA)
            ECS: ECs3784
            ECF: ECH74115_4208(serA)
            ETW: ECSP_3880(serA)
            EOJ: ECO26_3884 ECO26_4001(serA)
            EOI: ECO111_3539 ECO111_3650(serA)
            EOH: ECO103_3488(serA)
            ECG: E2348C_3081 E2348C_3164(serA)
            EOK: G2583_3568(serA)
            ECC: c3405 c3494(serA)
            ECP: ECP_2824 ECP_2905
            ECI: UTI89_C3212 UTI89_C3299(serA)
            ECV: APECO1_3616(serA) APECO1_3693
            ECX: EcHS_A3071(serA)
            ECW: EcE24377A_3240(serA)
            ECM: EcSMS35_2958 EcSMS35_3046(serA)
            ECY: ECSE_0272 ECSE_3175
            ECR: ECIAI1_3032(serA)
            ECQ: ECED1_3268 ECED1_3371(serA)
            ECK: EC55989_3200(serA)
            ECT: ECIAI39_3328(serA)
            EUM: ECUMN_3254(serA)
            ECZ: ECS88_3107 ECS88_3192(serA) ECS88_3862
            ECL: EcolC_0797
            EBR: ECB_02744(serA)
            EBD: ECBD_0825
            EFE: EFER_2850(serA)
            STY: STY3218(serA)
            STT: t2980(serA)
            STM: STM3062(serA)
            SPT: SPA2933(serA)
            SEK: SSPA2732
            SPQ: SPAB_03816
            SEI: SPC_3123(serA)
            SEC: SC3003(serA)
            SEH: SeHA_C3297(serA)
            SEE: SNSL254_A3300(serA)
            SEW: SeSA_A3235(serA)
            SEA: SeAg_B3223(serA)
            SED: SeD_A3402(serA)
            SEG: SG2957(serA)
            SET: SEN2905(serA)
            SES: SARI_04588
            YPE: YPO0914(serA) YPO1288
            YPK: y2896 y3301(serA)
            YPA: YPA_0353 YPA_1004
            YPN: YPN_2690 YPN_3113
            YPM: YP_1303(serA1) YP_3611(serA2)
            YPP: YPDSF_0599 YPDSF_2408
            YPG: YpAngola_A1514 YpAngola_A3823(serA)
            YPZ: YPZ3_0810(serA) YPZ3_1177
            YPS: YPTB1320 YPTB3189(serA)
            YPI: YpsIP31758_0856(serA) YpsIP31758_2694
            YPY: YPK_0859 YPK_2773
            YPB: YPTS_1412 YPTS_3321
            YEN: YE2604 YE3400(serA)
            SFL: SF2898(serA)
            SFX: S3098(serA)
            SFV: SFV_2960(serA)
            SSN: SSON_3065(serA)
            SBO: SBO_2700 SBO_3080(serA)
            SBC: SbBS512_E3053 SbBS512_E3333(serA)
            SDY: SDY_3169(serA)
            ECA: ECA3905(serA)
            PCT: PC1_2719 PC1_3682
            PWA: Pecwa_3876
            ETA: ETA_28070(serA)
            EPY: EpC_29500(serA)
            EAM: EAMY_0632(serA)
            EAY: EAM_2798(serA)
            EBI: EbC_07650 EbC_25480 EbC_36490(serA)
            PLU: plu3605(serA)
            PAY: PAU_01152(serA)
            SGL: SG2009
            ENT: Ent638_3332
            ENC: ECL_04239 ECL_04872
            ESC: Entcl_0840
            ESA: ESA_00416
            CTU: Ctu_34620(serA)
            KPN: KPN_00636 KPN_03348(serA)
            KPE: KPK_0752(serA) KPK_2753(gyaR) KPK_3939
            KPU: KP1_1587 KP1_4635(serA)
            KVA: Kvar_0720 Kvar_1023 Kvar_3731
            CKO: CKO_04278
            CRO: ROD_43131 ROD_49181(serA)
            SPE: Spro_3923
            PMR: PMI2031(serA)
            EIC: NT01EI_3360
            ETR: ETAE_2949
            HDE: HDEF_2074(serA)
            DDA: Dd703_0561 Dd703_3000
            DDC: Dd586_0910
            DDD: Dda3937_00407(serA) Dda3937_00861
            DZE: Dd1591_0520 Dd1591_3184
            XBO: XBJ1_3444(serA)
            XNE: XNC1_1100(serA)
            PAM: PANA_1607(gyaR) PANA_2952(serA) PANA_3196(serA)
            PVA: Pvag_2537(serA) Pvag_pPag30144 Pvag_pPag30411(serA)
            PAO: Pat9b_0706 Pat9b_3192 Pat9b_4426 Pat9b_4542 Pat9b_5196
                 Pat9b_5680
            HIN: HI0465(serA)
            HIT: NTHI0596(serA)
            HIP: CGSHiEE_00665
            HIQ: CGSHiGG_05565
            HIF: HIBPF18640
            HIL: HICON_09490
            HAP: HAPS_1043(serA)
            HSO: HS_0122(serA)
            HSM: HSM_2007
            PMU: PM1671(serA)
            MSU: MS0068(serA) MS1743(serA)
            APL: APL_1452(serA)
            APJ: APJL_1474(serA)
            APA: APP7_1457
            ASU: Asuc_1869
            AAP: NT05HA_2355
            AAT: D11S_1510
            XFA: XF2206
            XFT: PD1255(serA)
            XFM: Xfasm12_1407
            XFN: XfasM23_1340
            XCC: XCC0020(serA) XCC1825(serA)
            XCB: XC_0020 XC_2364
            XCA: xccb100_0022(serA2) xccb100_2112(serA1)
            XCV: XCV0023(serA) XCV1890(serA)
            XAC: XAC0022(serA) XAC1844(serA)
            XOO: XOO2143(serA) XOO4585(serA)
            XOM: XOO_2012 XOO_4321
            XOP: PXO_00852 PXO_03548
            XAL: XALc_0394(serA) XALc_1326(serA)
            SML: Smlt2195(serA)
            SMT: Smal_1787
            PSU: Psesu_1805
            VCH: VC2481 VCA0630
            VCO: VC0395_0573 VC0395_A2057(serA)
            VCM: VCM66_2403(serA) VCM66_A0588
            VCJ: VCD_000692 VCD_001875
            VVU: VV1_1546 VV2_0975
            VVY: VV2851 VVA1466
            VVM: VVM_00886 VVM_02875
            VPA: VP2593
            VHA: VIBHAR_03556
            VSP: VS_1609 VS_2640
            VEX: VEA_002479
            VFI: VF_2106(serA)
            VFM: VFMJ11_2211
            VSA: VSAL_I2544(serA)
            PPR: PBPRA3123 PBPRA3124
            PAE: PA0316(serA)
            PAU: PA14_04110(serA)
            PAP: PSPA7_0409(serA)
            PAG: PLES_03121(serA)
            PPU: PP_2533 PP_5155(serA)
            PPF: Pput_3187 Pput_5062
            PPG: PputGB1_5208
            PPW: PputW619_0310
            PST: PSPTO_5294(serA)
            PSB: Psyr_4852
            PSP: PSPPH_4885(serA)
            PFL: PFL_5911
            PFO: Pfl01_2987 Pfl01_5387
            PFS: PFLU2307 PFLU5829(serA)
            PEN: PSEEN5248(serA)
            PMY: Pmen_4232
            PSA: PST_0398(serA)
            CJA: CJA_0232 CJA_1072
            AVN: Avin_39750 Avin_48330(serA)
            PAR: Psyc_0369(serA)
            PCR: Pcryo_0410
            PRW: PsycPRwf_0569
            ACI: ACIAD3302(serA)
            ACD: AOLE_01695 AOLE_09035
            ACB: A1S_3152
            ABM: ABSDF0338(serA)
            ABY: ABAYE0332(serA)
            ABC: ACICU_01895 ACICU_03352
            ABN: AB57_3607
            ABB: ABBFA_000359
            MCT: MCR_0259(serA)
            SON: SO_0862(serA)
            SDN: Sden_3097
            SFR: Sfri_0558
            SAZ: Sama_2949
            SBL: Sbal_3502
            SBM: Shew185_0838
            SBN: Sbal195_0873
            SBP: Sbal223_0861
            SLO: Shew_3196
            SPC: Sputcn32_3139
            SSE: Ssed_3947
            SPL: Spea_0631
            SHE: Shewmr4_0718
            SHM: Shewmr7_3304
            SHN: Shewana3_3416
            SHW: Sputw3181_0804
            SHL: Shal_0723
            SWD: Swoo_3889
            SWP: swp_1563 swp_4448
            SVO: SVI_3665(serA)
            ILO: IL2104(serA)
            CPS: CPS_1544(serA)
            PHA: PSHAa0666(serA)
            PAT: Patl_1156
            PSM: PSM_A2397(serA)
            SDE: Sde_1333 Sde_3388
            MAQ: Maqu_2819
            AMC: MADE_03208
            PIN: Ping_0600
            TTU: TERTU_0393 TERTU_2749
            FBL: Fbal_0688
            CBU: CBU_1732
            CBS: COXBURSA331_A1924
            CBD: CBUD_0270
            CBG: CbuG_0113
            CBC: CbuK_0275
            LPN: lpg0242(serA)
            LPF: lpl0296
            LPP: lpp0312
            LLO: LLO_0726 LLO_3163
            FTU: FTT_1230(serA)
            FTF: FTF1230(serA)
            FTL: FTL_0714
            FTH: FTH_0716(serA)
            FTA: FTA_0754
            FTM: FTM_0713(serA)
            FPH: Fphi_1431
            TCX: Tcr_0627
            NOC: Noc_0173
            NHL: Nhal_2630
            NWA: Nwat_0173
            ALV: Alvin_2085
            AEH: Mlg_0925
            HHA: Hhal_0569
            TGR: Tgr7_1472 Tgr7_1537
            TKM: TK90_1206
            HNA: Hneap_1337
            HCH: HCH_01646(serA)
            CSA: Csal_0096 Csal_1770
            HEL: HELO_1081(serA)
            ABO: ABO_0068(serA)
            KKO: Kkor_2479
            MMW: Mmwyl1_1580 Mmwyl1_4310
            AHA: AHA_2731 AHA_3354
            ASA: ASA_0954(serA) ASA_1641(serA)
            TAU: Tola_1366
            AFE: Lferr_1018
            AFR: AFE_0896(serA)
            RMA: Rmag_0627
            VOK: COSY_0580(serA)
            GPB: HDN1F_04140(serA)
            LHK: LHK_02185
            RSO: RSc0016(serA1) RSp0505(serA2)
            RSC: RCFBP_21431(serA)
            RSL: RPSI07_3364(serA)
            RPI: Rpic_3740 Rpic_3984
            RPF: Rpic12D_3417 Rpic12D_4097
            REU: Reut_A3421 Reut_B3530 Reut_B4615 Reut_B4747 Reut_C5898
            REH: H16_A3712(serA1) H16_B0347(serA2) H16_B0824(serA4)
                 H16_B0841(serA5) H16_B1819(serA6)
            RME: Rmet_3578 Rmet_4234 Rmet_4537(serA2)
            CTI: RALTA_A3168(serA3) RALTA_B0655(serA1) RALTA_B0841(serA2)
                 RALTA_B1944
            BMA: BMA0137
            BMV: BMASAVP1_A2813
            BML: BMA10229_A2269
            BMN: BMA10247_2346
            BPS: BPSL0116 BPSL1250(serA)
            BPM: BURPS1710b_0341(serA1) BURPS1710b_1481
            BPL: BURPS1106A_0151(gyaR) BURPS1106A_1345(serA)
            BPD: BURPS668_0143 BURPS668_1338(serA)
            BPR: GBP346_A0055 GBP346_A1360
            BTE: BTH_I0123 BTH_I2885(serA) BTH_II0982
            BVI: Bcep1808_3291
            BUR: Bcep18194_A3727 Bcep18194_A6483 Bcep18194_B0500 Bcep18194_B0965
                 Bcep18194_B1312 Bcep18194_C7658
            BCN: Bcen_2519 Bcen_3835 Bcen_5465
            BCH: Bcen2424_3132 Bcen2424_4533 Bcen2424_5397
            BCM: Bcenmc03_3148 Bcenmc03_4873 Bcenmc03_5771
            BCJ: BCAL0460 BCAM1715 BCAM2587(serA)
            BAM: Bamb_3187
            BAC: BamMC406_3070
            BMU: Bmul_3129 Bmul_4705
            BMJ: BMULJ_00101(serA) BMULJ_03811(serA)
            BXE: Bxe_A2676 Bxe_B1744 Bxe_B1896 Bxe_B2128
            BPH: Bphy_0029 Bphy_6028 Bphy_6995
            BPY: Bphyt_0303 Bphyt_6458
            BGL: bglu_1g34150
            BGE: BC1002_0019
            BRH: RBRH_01278
            BPE: BP0155(serA)
            BPA: BPP2132 BPP4001(serA)
            BBR: BB1529 BB4474(serA) BB4731
            BPT: Bpet0409(serA2) Bpet0479(serA3) Bpet3356(serA4) Bpet3803(serA5)
                 Bpet3817(serA6)
            BAV: BAV3093(serA)
            AXY: AXYL_00471(serA1) AXYL_00491(serA2) AXYL_04203
            TEQ: TEQUI_0604
            RFR: Rfer_1867 Rfer_2996
            POL: Bpro_2956 Bpro_4572 Bpro_5117
            PNA: Pnap_1854 Pnap_1916
            AAV: Aave_3158 Aave_3649
            AJS: Ajs_0863 Ajs_1926
            DIA: Dtpsy_0792 Dtpsy_1729
            VEI: Veis_0891 Veis_1307 Veis_1427 Veis_2017 Veis_3989 Veis_4913
            DAC: Daci_0347 Daci_1381 Daci_3541 Daci_4276 Daci_5796
            VAP: Vapar_2634 Vapar_3820 Vapar_4133 Vapar_5586 Vapar_6256
            VPE: Varpa_3128 Varpa_3293 Varpa_3905 Varpa_4804
            CTT: CtCNB1_0270 CtCNB1_2857
            ADN: Alide_0349 Alide_0949 Alide_2176
            MPT: Mpe_A1136 Mpe_A1820
            HAR: HEAR3340 HEAR3458(tkrA)
            MMS: mma_3685(serA)
            HSE: Hsero_3336(serA) Hsero_4313(serA) Hsero_4453(serA)
            LCH: Lcho_0717 Lcho_1907 Lcho_3015 Lcho_3627
            TIN: Tint_3193
            NEU: NE0334 NE1688(serA)
            NET: Neut_0433 Neut_1571
            NMU: Nmul_A0428 Nmul_A2191
            EBA: ebA6869(serA)
            AZO: azo3099(serA)
            TBD: Tbd_0950
            MFA: Mfla_0724
            APP: CAP2UW1_2565
            SLT: Slit_2066
            GCA: Galf_1138
            HPY: HP0397
            HPJ: jhp0984(serA)
            HPA: HPAG1_0995
            HPS: HPSH_05420
            HPG: HPG27_1000
            HPP: HPP12_1023(serA)
            HPB: HELPY_1028(serA)
            HPL: HPB8_448(serA)
            HPC: HPPC_05120
            HPM: HPSJM_05200
            HHE: HH0135(serA)
            HAC: Hac_0455(serA)
            HMS: HMU01550
            HFE: Hfelis_14530
            WSU: WS1313(serA)
            TDN: Suden_0875
            SKU: Sulku_0886 Sulku_2398
            CJE: Cj0891c(serA)
            CJR: CJE0970(serA)
            CJJ: CJJ81176_0900(serA)
            CJU: C8J_0828(serA)
            CJN: ICDCCJ_846
            CJD: JJD26997_0922(serA)
            CFF: CFF8240_1248(serA)
            CCV: CCV52592_0512(serA)
            CHA: CHAB381_0480(serA)
            CCO: CCC13826_1569(serA)
            CLA: Cla_1188(serA)
            ABU: Abu_2048(serA)
            ANT: Arnit_0487 Arnit_1196 Arnit_1990
            SDL: Sdel_0615 Sdel_1201
            NIS: NIS_0664
            SUN: SUN_0551
            NSA: Nitsa_0332
            NAM: NAMH_0913(serA)
            GSU: GSU1198(serA)
            GME: Gmet_2378
            GUR: Gura_1737 Gura_3860
            GLO: Glov_2087
            GBM: Gbem_1961(serA)
            GEO: Geob_3435
            GEM: GM21_2256
            PCA: Pcar_0417(serA-1) Pcar_3115(serA-2)
            PPD: Ppro_0734 Ppro_1699
            DVU: DVU0339
            DVL: Dvul_2644
            DVM: DvMF_1902
            DDE: Dde_3689
            DDS: Ddes_0277
            DAS: Daes_0102 Daes_2365
            LIP: LI0671(serA)
            BBA: Bd1461(serA) Bd2892(serA)
            DPS: DP1709
            DAK: DaAHT2_0597
            DPR: Despr_0935
            DOL: Dole_2813 Dole_2852
            DAL: Dalk_3379
            DAT: HRM2_35500(serA1)
            ADE: Adeh_1262
            ACP: A2cp1_2694 A2cp1_3156
            AFW: Anae109_2506 Anae109_2907
            ANK: AnaeK_2601 AnaeK_3048
            MXA: MXAN_6356(serA)
            SCL: sce1526 sce4153(serA1) sce5802(serA2)
            HOH: Hoch_4608
            SAT: SYN_00123
            SFU: Sfum_3136 Sfum_3649
            DBR: Deba_0722
            PUB: SAR11_1366(serA)
            MLO: mll1021 mll3875 mlr3367 mlr7269
            MCI: Mesci_1304 Mesci_1660 Mesci_5287 Mesci_6404
            MES: Meso_3161
            PLA: Plav_2138
            SME: SMa1347 SMc00641(serA) SMc01622
            SMD: Smed_2158 Smed_2466 Smed_2618 Smed_5864 Smed_5903
            RHI: NGR_b04550 NGR_b17460 NGR_c27700
            ATU: Atu3706(serA) Atu5399
            ARA: Arad_0100(serA) Arad_10005(serA) Arad_3664(serA)
                 Arad_7653(serA) Arad_7972(serA)
            AVI: Avi_3595(serA) Avi_7079(serA)
            RET: RHE_CH03454(serA) RHE_PC00143(ypc00078) RHE_PF00379(ypf00200)
            REC: RHECIAT_CH0002310 RHECIAT_CH0003693(serA)
            RLE: RL3960 pRL100390 pRL120588
            RLT: Rleg2_3192 Rleg2_5216
            RLG: Rleg_3486 Rleg_4983
            LAS: CLIBASIA_00175
            BME: BMEI0349 BMEII0813
            BMI: BMEA_A1738(serA) BMEA_B0432
            BMF: BAB1_1697 BAB2_0783(serA-2)
            BMB: BruAb1_1670(serA-1) BruAb2_0769(serA-2)
            BMC: BAbS19_I15880 BAbS19_II07270
            BMS: BR1685(serA-1) BRA0453(serA-2)
            BMT: BSUIS_B0454 BSUIS_B1160(serA)
            BOV: BOV_1629(serA)
            BCS: BCAN_A1723(serA) BCAN_B0455
            BMR: BMI_I1706(serA-1) BMI_II450(serA-2)
            OAN: Oant_1229 Oant_3104
            BJA: bll6549 bll7401(serA) bll7965 blr3173
            BRA: BRADO1760(serA) BRADO2535 BRADO3813 BRADO3860 BRADO4794
                 BRADO4922 BRADO5741 BRADO5948(serA)
            BBT: BBta_1826(serA) BBta_2073(serA) BBta_2880 BBta_3129 BBta_3231
                 BBta_4121 BBta_6253
            RPA: RPA1744(serA) RPA2975(serA1) RPA4308(serA2)
            RPB: RPB_1315 RPB_4226
            RPC: RPC_1669 RPC_4106
            RPD: RPD_3905 RPD_4078
            RPE: RPE_4160
            RPT: Rpal_1944 Rpal_3323 Rpal_4789
            RPX: Rpdx1_2466 Rpdx1_3787 Rpdx1_4524
            NWI: Nwi_2968
            NHA: Nham_1119
            OCA: OCAR_7157(serA) OCAR_7552
            BGR: Bgr_13640
            XAU: Xaut_1202 Xaut_2822 Xaut_3822
            AZC: AZC_0179 AZC_0758 AZC_0985 AZC_3025
            SNO: Snov_0173 Snov_3003
            MEX: Mext_0213 Mext_0660
            MEA: Mex_1p0105(serA) Mex_1p0486(serA)
            MDI: METDI0094(serA) METDI0641(serA2)
            MRD: Mrad2831_1426 Mrad2831_1474 Mrad2831_2449 Mrad2831_3405
                 Mrad2831_4214 Mrad2831_4405 Mrad2831_5977
            MET: M446_3767 M446_6394 M446_6454
            MPO: Mpop_0639 Mpop_2979
            MCH: Mchl_0672
            MNO: Mnod_2863 Mnod_6798
            BID: Bind_1269 Bind_2829
            MSL: Msil_1760
            RVA: Rvan_2957 Rvan_3575
            CCR: CC_3215
            CCS: CCNA_03322
            CAK: Caul_4467
            CSE: Cseg_0705 Cseg_2984
            PZU: PHZ_c3272(serA)
            BSB: Bresu_1707
            AEX: Astex_2107
            SIL: SPO3355(serA)
            SIT: TM1040_3021
            RSP: RSP_1352 RSP_3407(serA) RSP_3447
            RSH: Rsph17029_0020 Rsph17029_3052 Rsph17029_3092
            RSQ: Rsph17025_0010 Rsph17025_2050
            RSK: RSKD131_2750 RSKD131_3572 RSKD131_3613 RSKD131_4358
            RCP: RCAP_rcc03447(serA)
            JAN: Jann_0261
            RDE: RD1_0197(serA) RD1_3633(serA)
            PDE: Pden_0814 Pden_3433
            DSH: Dshi_1001(serA2) Dshi_3318(serA1)
            KVU: EIO_0005 EIO_2961(serA)
            HNE: HNE_3126(serA)
            HBA: Hbal_1531 Hbal_2411
            ZMO: ZMO1685
            ZMN: Za10_1534
            NAR: Saro_2680
            SAL: Sala_0616
            SWI: Swit_4685
            SJP: SJA_C1-01840(serA)
            ELI: ELI_01970
            GOX: GOX0065 GOX0218
            ACR: Acry_2572 Acry_2650
            GDI: GDI_0211 GDI_1473 GDI_1874(serA)
            GDJ: Gdia_0098 Gdia_2280
            APT: APA01_11910
            RRU: Rru_A2456
            RCE: RC1_1786(serA)
            MAG: amb3193
            AZL: AZL_004920(serA) AZL_010500(serA) AZL_a09310(serA) AZL_b00610
            PBR: PB2503_01827
            APB: SAR116_1741 SAR116_2307
            MGM: Mmc1_1423
            DIN: Selin_0361
            BSU: BSU18560(yoaD) BSU23070(serA)
            BSS: BSUW23_09900(yoaD) BSUW23_11330(serA)
            BHA: BH1602
            BAN: BA_3320
            BAR: GBAA_3320
            BAT: BAS3078
            BAH: BAMEG_1305
            BAI: BAA_3355
            BAL: BACI_c32170
            BCE: BC3248
            BCA: BCE_3284
            BCZ: BCZK1299(serA) BCZK2968(serA)
            BCR: BCAH187_A3293
            BCB: BCB4264_A3260
            BCU: BCAH820_3298
            BCG: BCG9842_B1989
            BCQ: BCQ_3074
            BCX: BCA_3352
            BCY: Bcer98_2085
            BTK: BT9727_3022(serA)
            BTL: BALH_1270(serA) BALH_2945(serA)
            BTB: BMB171_C2919
            BWE: BcerKBAB4_2986
            BLI: BL00647(serA)
            BLD: BLi02446(serA)
            BAY: RBAM_018760(yoaD) RBAM_021220(serA)
            BAO: BAMF_1971(yoaD) BAMF_2207(serA)
            BAE: BATR1942_08160 BATR1942_09415
            BCL: ABC0220 ABC1843(serA)
            BPU: BPUM_2039(serA)
            BPF: BpOF4_15180(serA)
            BMQ: BMQ_2421 BMQ_4365(serA)
            BMD: BMD_2386 BMD_4351(serA)
            BSE: Bsel_2170
            BCO: Bcell_2366
            OIH: OB2626(serA)
            GKA: GK2247
            GTN: GTNG_2184
            GWC: GWCH70_2197
            GYM: GYMC10_2168 GYMC10_3582
            GYC: GYMC61_0432
            GYA: GYMC52_2230
            GCT: GC56T3_1254 GC56T3_1560
            GMC: GY4MC1_1305
            AFL: Aflv_1055(serA)
            SAU: SA1545(serA)
            SAV: SAV1724(serA)
            SAW: SAHV_1710(serA)
            SAH: SaurJH1_1814
            SAJ: SaurJH9_1779
            SAM: MW1666(serA)
            SAS: SAS1650
            SAR: SAR1801
            SAC: SACOL1773(serA)
            SAX: USA300HOU_1712(serA)
            SAA: SAUSA300_1670(serA)
            SAO: SAOUHSC_01833
            SAE: NWMN_1617(serA)
            SAD: SAAV_1734(serA)
            SAB: SAB1582
            SEP: SE1401
            SER: SERP1288(serA)
            SHA: SH1200(serA)
            SSP: SSP1039
            SCA: Sca_1330(serA)
            SLG: SLGD_01207
            SSD: SPSINT_1493
            LMO: lmo2824
            LMF: LMOf2365_2815
            LMH: LMHCC_2697
            LMC: Lm4b_02797
            LMN: LM5578_0033
            LMY: LM5923_0033
            LIN: lin2956
            LWE: lwe2754
            LSG: lse_2705
            LSP: Bsph_0386
            ESI: Exig_1690
            EAT: EAT1b_0622
            BBE: BBR47_24220(serA)
            PJD: Pjdr2_2370
            PPY: PPE_02781(serA)
            PPM: PPSC2_c3155
            AAC: Aaci_1231
            BTS: Btus_0927 Btus_1805
            LLA: L0084(serA)
            LLK: LLKF_0582(serA)
            LLC: LACR_0620
            LLM: llmg_0566(serA)
            SAG: SAG1566
            SAN: gbs1619
            SAK: SAK_1584
            SMU: SMU.1653(serA)
            SMC: SmuNN2025_0464(serA)
            STC: str1527(serA)
            STL: stu1527(serA)
            STE: STER_1487
            SSA: SSA_1713(serA) SSA_2085
            SSU: SSU05_0667
            SSV: SSU98_0667
            SSB: SSUBM407_1201
            SSI: SSU0623
            SSS: SSUSC84_0596
            SUB: SUB0447
            SGA: GALLO_0848 GALLO_1744(serA)
            LPL: lp_0203(serA1) lp_2790(serA3)
            LPJ: JDM1_0188(serA1)
            LPS: LPST_C0165(serA1)
            LSA: LSA0922(serA)
            LSL: LSL_0092(serA)
            LDE: LDBND_0927
            LHE: lhv_0049
            LFE: LAF_0769 LAF_1801
            LRL: LC705_00400(serA)
            LME: LEUM_1463
            LCI: LCK_00351 LCK_00558 LCK_01533
            LKI: LKI_02155 LKI_02870 LKI_05460
            LGS: LEGAS_0078(serA2) LEGAS_1250(serA) LEGAS_1364(serA3) LEGAS_1453
            CAC: CA_C0015(serA) CA_C0089(serA)
            CPE: CPE0054(serA)
            CPF: CPF_0061
            CPR: CPR_0064
            CTC: CTC00694
            CNO: NT01CX_0728(serA)
            CTH: Cthe_3035
            CDF: CD0995(serA)
            CDC: CD196_0868(serA)
            CDL: CDR20291_0848(serA)
            CBO: CBO1127(serA)
            CBA: CLB_1164(serA)
            CBH: CLC_1176(serA)
            CBY: CLM_1283
            CBL: CLK_0567(serA)
            CBK: CLL_A3438
            CBB: CLD_3436(serA)
            CBI: CLJ_B1174
            CBT: CLH_3217
            CBF: CLI_1213(serA)
            CBE: Cbei_4927
            CKL: CKL_0436(serA) CKL_3816
            CKR: CKR_0381 CKR_3370
            CPY: Cphy_1465 Cphy_3382
            CCE: Ccel_1189
            CLJ: CLJU_c00970 CLJU_c03860 CLJU_c11580 CLJU_c11620 CLJU_c30610
                 CLJU_c32780(serA)
            CSH: Closa_3653
            CCB: Clocel_2018
            CST: CLOST_1813
            AMT: Amet_3604 Amet_4275
            STH: STH9
            SWO: Swol_0009
            SLP: Slip_0010
            AFN: Acfer_0068 Acfer_0073 Acfer_2029 Acfer_2034
            DSY: DSY0969 DSY4683
            DHD: Dhaf_2054 Dhaf_3417 Dhaf_4578
            DRM: Dred_0014
            DAE: Dtox_4340
            PTH: PTH_0012(serA)
            DAU: Daud_0012
            TJR: TherJR_0013
            HMO: HM1_0851(serA)
            EEL: EUBELI_00765
            ERE: EUBREC_1207 EUBREC_1874
            ELM: ELI_0434 ELI_0529 ELI_0730
            BPB: bpr_I1342(serA)
            EHA: Ethha_0033 Ethha_2251
            RAL: Rumal_1020
            TMR: Tmar_0517 Tmar_1044
            TTE: TTE2613(serA2)
            TEX: Teth514_0124 Teth514_0128 Teth514_0136 Teth514_1916
                 Teth514_2306
            TPD: Teth39_0145 Teth39_1970 Teth39_2066 Teth39_2074 Teth39_2078
            TIT: Thit_0157 Thit_0161 Thit_0169 Thit_1574 Thit_2266
            TMT: Tmath_0214 Tmath_0218 Tmath_0226 Tmath_2173
            TBO: Thebr_0151 Thebr_2017 Thebr_2111 Thebr_2119 Thebr_2123
            CHY: CHY_2698(serA)
            MTA: Moth_0020
            ADG: Adeg_0010
            CSC: Csac_1304
            ATE: Athe_1994 Athe_2125
            COB: COB47_1906
            CHD: Calhy_0502 Calhy_0632 Calhy_2453
            COW: Calow_1815
            CKI: Calkr_0457
            CKN: Calkro_0510
            TOC: Toce_1898
            TTM: Tthe_2467 Tthe_2593
            HOR: Hore_11540
            HAS: Halsa_1988
            AAR: Acear_0027
            MTU: Rv0728c(serA2) Rv2996c(serA1)
            MTC: MT0753 MT3074(serA)
            MRA: MRA_0736(serA2) MRA_3025(serA1)
            MTF: TBFG_10742 TBFG_13011
            MTB: TBMG_00742(TBMG_00742.1) TBMG_00974(TBMG_00974.1)
            MBO: Mb0749c(serA2) Mb3020c(serA1)
            MBB: BCG_0778c(serA2) BCG_3017c(serA1)
            MBT: JTY_0748(serA2) JTY_3012(serA1)
            MLE: ML1692(serA)
            MLB: MLBr_01692(serA)
            MPA: MAP3033c(serA) MAP4194c
            MAV: MAV_0349 MAV_3847(serA) MAV_4438
            MSM: MSMEG_2378(serA)
            MUL: MUL_0823(serA2) MUL_1952(serA1)
            MVA: Mvan_2128
            MGI: Mflv_4234
            MAB: MAB_3304c
            MMC: Mmcs_1910
            MKM: Mkms_1956
            MJL: Mjls_1890
            MSP: Mspyr1_35790
            MMI: MMAR_1065(serA2) MMAR_1715(serA1)
            CGL: NCgl1235(cgl1284)
            CGB: cg1451(serA)
            CGT: cgR_1362
            CEF: CE1379
            CDI: DIP1104(serA)
            CJK: jk1291(serA)
            CUR: cur_0759
            CAR: cauri_1135(serA)
            CKP: ckrop_1236
            CPU: cpfrc_00898(serA)
            NFA: nfa42210(serA)
            RHA: RHA1_ro02903(serA1) RHA1_ro03298 RHA1_ro04630
                 RHA1_ro06489(serA2) RHA1_ro08844(serA3) RHA1_ro08891
            RER: RER_24000(serA)
            ROP: ROP_05010 ROP_47270(hprA) ROP_65420(serA)
            REQ: REQ_31440 REQ_43370 REQ_43480
            GBR: Gbro_3225
            TPR: Tpau_1543 Tpau_2856
            SRT: Srot_2054
            SCO: SCO5515(SC8D9.27)
            SMA: SAV_2730(serA) SAV_7481
            SGR: SGR_1997 SGR_223
            SCB: SCAB_27051(serA)
            LXX: Lxx13140(serA)
            CMI: CMM_1100(serA)
            CMS: CMS_1420(serA)
            ART: Arth_2536
            AAU: AAur_2506(serA) AAur_pTC20110
            ACH: Achl_0132 Achl_2276
            AAI: AARI_14060(serA)
            RSA: RSal33209_1046
            KRH: KRH_20570(serA)
            MLU: Mlut_08560
            BCV: Bcav_1686 Bcav_2429
            BFA: Bfae_18780
            JDE: Jden_1058
            XCE: Xcel_1261
            SKE: Sked_22990
            CFL: Cfla_1571
            ICA: Intca_2357
            PAC: PPA1272 PPA2251
            PAK: HMPREF0675_4337
            PFR: PFREUD_10080 PFREUD_21910
            NCA: Noca_3385 Noca_3951
            KFL: Kfla_4884 Kfla_6644
            TFU: Tfu_0614
            NDA: Ndas_0174
            TCU: Tcur_0451 Tcur_3546
            SRO: Sros_8047 Sros_8241
            FRA: Francci3_3637
            FRE: Franean1_1093
            FRI: FraEuI1c_1016 FraEuI1c_3545 FraEuI1c_5629
            FAL: FRAAL5848(serA) FRAAL6376
            ACE: Acel_0709
            NML: Namu_1471
            GOB: Gobs_2440 Gobs_2471 Gobs_4068
            KRA: Krad_1513
            SEN: SACE_4226(serA) SACE_4558(serA) SACE_4605(serA) SACE_5219(serA)
                 SACE_6155(serA)
            SVI: Svir_08910 Svir_32100
            TBI: Tbis_1582 Tbis_2435 Tbis_2814
            AMD: AMED_1694(serA)
            AMI: Amir_4166 Amir_6017
            STP: Strop_1236
            SAQ: Sare_0567 Sare_1126
            MAU: Micau_1305
            MIL: ML5_1551
            CAI: Caci_7791
            SNA: Snas_1558 Snas_4069 Snas_4312
            MCU: HMPREF0573_10634(serA) HMPREF0573_11568(serA2)
            BLO: BL1313(serA)
            BLJ: BLD_0170(serA2)
            BLN: Blon_0845
            BLL: BLJ_1306
            BLB: BBMN68_198(serA2)
            BAD: BAD_1112(serA)
            BLA: BLA_0787(serA)
            BLC: Balac_1209
            BLT: Balat_1209
            BDE: BDP_1553(serA1)
            BBI: BBIF_0569(serA)
            BBP: BBPR_0545(serA)
            RXY: Rxyl_0837
            CWO: Cwoe_0118 Cwoe_2098 Cwoe_3561 Cwoe_4320
            AFO: Afer_1530
            CCU: Ccur_03390
            SHI: Shel_28220
            ELE: Elen_0965 Elen_1873
            OLS: Olsu_0010 Olsu_0716
            WCH: wcw_0057(serA)
            SSM: Spirs_0779 Spirs_0924 Spirs_0994 Spirs_1672 Spirs_2138
                 Spirs_2393 Spirs_3738
            LIL: LA_1629(serA) LA_1911(serA)
            LIC: LIC11992(serA)
            LBJ: LBJ_1496
            LBL: LBL_1720
            LBI: LEPBI_I1899(serA2) LEPBI_I2005(serA1)
            LBF: LBF_1844 LBF_1952
            BHY: BHWA1_00562(serA)
            BRM: Bmur_2694
            BPO: BP951000_0366(serA)
            ABA: Acid345_0115
            ACA: ACP_2392(serA)
            TSA: AciPR4_0546
            SUS: Acid_1661 Acid_5922
            BTH: BT_1152
            BFR: BF2019
            BFS: BF2073(serA)
            BVU: BVU_3242
            BHL: Bache_2615
            PGI: PG1279
            PGN: PGN_0611
            PDI: BDI_0506
            PPN: Palpr_1740
            APS: CFPG_743
            PRU: PRU_1036(serA)
            PMZ: HMPREF0659_A6812
            RMR: Rmar_1474
            CHU: CHU_0996(serA) CHU_1630(ldhA)
            DFE: Dfer_0419 Dfer_3130 Dfer_4690
            SLI: Slin_0324 Slin_1074
            LBY: Lbys_0229 Lbys_0364 Lbys_1245
            MTT: Ftrac_0702 Ftrac_3193
            CPI: Cpin_1239 Cpin_3752
            PHE: Phep_0261 Phep_1858 Phep_3505 Phep_3811
            GFO: GFO_0734(serA) GFO_1469(serA) GFO_3512(serA)
            FJO: Fjoh_0839 Fjoh_2461
            FPS: FP0064 FP0639(serA)
            COC: Coch_1659 Coch_1745
            RBI: RB2501_00101 RB2501_05020 RB2501_15344
            ZPR: ZPR_0459 ZPR_2134 ZPR_2876
            CAT: CA2559_03740 CA2559_08686
            RAN: Riean_0149 Riean_1573
            FBC: FB2170_04230 FB2170_10731 FB2170_13643
            CAO: Celal_0040 Celal_1890 Celal_4203
            FBA: FIC_00155 FIC_00525 FIC_01053
            BBL: BLBBGE_283(serA)
            BPI: BPLAN_357(serA)
            FSU: Fisuc_2392 Fisuc_2660
            FNU: FN0965
            LBA: Lebu_1043
            STR: Sterm_2699 Sterm_3551
            IPO: Ilyop_0567
            OTE: Oter_3521 Oter_4261
            CAA: Caka_2599 Caka_2859
            MIN: Minf_1255(serA)
            AMU: Amuc_0705
            GAU: GAU_0195(serA)
            RBA: RB10004(serA) RB6248(serA) RB6394
            PSL: Psta_0833 Psta_2972 Psta_4745
            PLM: Plim_1680 Plim_2827
            IPA: Isop_0186 Isop_0723 Isop_3664
            ACO: Amico_1309 Amico_1753
            SYN: sll1908(serA)
            SYW: SYNW0533(serA)
            SYC: syc2486_c(serA)
            SYF: Synpcc7942_1501
            SYD: Syncc9605_2150
            SYE: Syncc9902_0527
            SYG: sync_2256(serA)
            SYR: SynRCC307_1844(serA)
            SYX: SynWH7803_1981(serA)
            SYP: SYNPCC7002_A1246(serA)
            CYA: CYA_1354(serA)
            CYB: CYB_1383(serA)
            TEL: tlr0325(serA)
            MAR: MAE_50690(serA)
            CYT: cce_2134(serA)
            CYP: PCC8801_0053 PCC8801_2377
            CYC: PCC7424_4778
            CYN: Cyan7425_3375
            CYH: Cyan8802_0051 Cyan8802_2428
            CYJ: Cyan7822_2869
            CYU: UCYN_12720
            GVI: gvip294(serA)
            ANA: alr1890
            NPU: Npun_R5218
            AVA: Ava_3759
            NAZ: Aazo_2156
            PMA: Pro1436(serA)
            PMM: PMM1354(serA)
            PMT: PMT1431(serA)
            PMN: PMN2A_0926
            PMI: PMT9312_1452
            PMB: A9601_04421(engA) A9601_15551(serA)
            PMC: P9515_15151(serA)
            PMF: P9303_05241(serA)
            PMG: P9301_15401(serA)
            PMH: P9215_15831(serA)
            PMJ: P9211_12891 P9211_14091(serA)
            PME: NATL1_17821(serA)
            TER: Tery_4196
            AMR: AM1_1274(serA)
            CCH: Cag_1377
            CPH: Cpha266_1089
            CPB: Cphamn1_1569
            CLI: Clim_0967 Clim_1897
            PPH: Ppha_1520
            CTS: Ctha_0221
            DET: DET0599(serA)
            DEH: cbdb_A580(serA)
            DEB: DehaBAV1_0574
            DEV: DhcVS_539(serA)
            DEG: DehalGT_0536
            DLY: Dehly_0744
            RRS: RoseRS_0271
            RCA: Rcas_0263 Rcas_0608
            CAU: Caur_0280
            CAG: Cagg_3620
            CHL: Chy400_0300
            HAU: Haur_1084
            TRO: trd_1777 trd_1852
            STI: Sthe_0409 Sthe_1515
            ATM: ANT_06500 ANT_07000(serA)
            DRA: DR_1291
            DGE: Dgeo_0710
            DDR: Deide_09800 Deide_3p01400
            DMR: Deima_2230
            TRA: Trad_0302
            TTH: TTC0586 TTC1209
            TTJ: TTHA0952
            TSC: TSC_c10330(serA)
            MRB: Mrub_0173 Mrub_2461
            MSV: Mesil_1013 Mesil_2386
            OPR: Ocepr_1066
            AAE: aq_1905(serA)
            HYA: HY04AAS1_0786
            HTH: HTH_1866(serA)
            TAL: Thal_1470
            SUL: SYO3AOP1_0259
            SAF: SULAZ_1703(serA)
            PMX: PERMA_0333(serA)
            TAM: Theam_1510
            TMA: TM0327 TM1401
            TPT: Tpet_0592 Tpet_1382
            TLE: Tlet_0049 Tlet_1768
            TRQ: TRQ2_0606 TRQ2_1428
            TNA: CTN_0341 CTN_1190
            TNP: Tnap_0963 Tnap_1402
            TME: Tmel_0112
            TAF: THA_345(serA)
            FNO: Fnod_0103
            PMO: Pmob_0258
            KOL: Kole_2169
            DTH: DICTH_1665 DICTH_1741(serA)
            DTU: Dtur_0039 Dtur_1775
            TYE: THEYE_A0937(serA)
            NDE: NIDE3443(serA)
            TTR: Tter_0270 Tter_1436 Tter_2005 Tter_2057 Tter_2481
            DDF: DEFDS_0857(serA)
            DAP: Dacet_1260
            CNI: Calni_1129
            MJA: MJ_1018
            MFE: Mefer_0636
            MVU: Metvu_1427
            MFS: MFS40622_1631
            MIF: Metin_0517
            MMP: MMP1588(serA)
            MMQ: MmarC5_1821
            MMX: MmarC6_1082
            MMZ: MmarC7_0835
            MAE: Maeo_0567
            MVN: Mevan_0900
            MVO: Mvol_1155
            MAC: MA0592(serA)
            MBA: Mbar_A1431
            MMA: MM_1753
            MBU: Mbur_2385
            MMH: Mmah_1539
            MEV: Metev_0311
            MTP: Mthe_1224
            MHU: Mhun_3063
            MLA: Mlab_1543
            MEM: Memar_1850
            MPI: Mpet_0343
            MBN: Mboo_2164
            MPL: Mpal_0439
            MPD: MCP_0395(serA)
            MTH: MTH970
            MMG: MTBMA_c13560(serA)
            MST: Msp_1145(serA)
            MSI: Msm_0457
            MRU: mru_0678(serA)
            MFV: Mfer_0845
            MKA: MK0297 MK0319 MK0320(serA)
            AFU: AF0813(serA)
            APO: Arcpr_0691
            FPL: Ferp_2111
            HAL: VNG2424G(serA1)
            HSL: OE4408F(serA1)
            HMA: rrnAC0362(serA4) rrnAC1762(serA2) rrnAC2056(serA3)
                 rrnAC2451(serA5) rrnAC2696(serA1)
            HWA: HQ1043A(serA) HQ2066A(serA) HQ2909A(serA)
            NPH: NP0272A(serA)
            HLA: Hlac_2722
            HUT: Huta_1349 Huta_1491
            HMU: Hmuk_0199 Hmuk_0793
            HTU: Htur_0077
            NMG: Nmag_1887
            HVO: HVO_2968(serA3)
            HJE: HacjB3_00940 HacjB3_13890 HacjB3_15851
            HBO: Hbor_02900
            PTO: PTO0372
            PHO: PH0520 PH1387
            PAB: PAB0514(serA-like) PAB1008
            PFU: PF0370 PF1394
            TKO: TK0551 TK1966
            TON: TON_0569 TON_1463
            TGA: TGAM_0320(serA) TGAM_0565
            TSI: TSIB_1016 TSIB_1017
            TBA: TERMP_00727 TERMP_01571
            ABI: Aboo_1421
            RCI: RCIX1538(serA)
            SMR: Smar_0554
            SHC: Shell_0240
            IHO: Igni_0383
            DKA: DKAM_0857
            DMU: Desmu_0905
            TAG: Tagg_1146
            IAG: Igag_0374 Igag_1777
            SSO: SSO0905(serA-1) SSO3187(serA-2)
            STO: ST0694 ST1218
            SAI: Saci_0247 Saci_1368
            SIS: LS215_1403
            SIA: M1425_1316
            SIM: M1627_1366
            SID: M164_1299
            SIY: YG5714_1310
            SIN: YN1551_1547
            SII: LD85_1428
            MSE: Msed_1059 Msed_1283 Msed_1675
            PAI: PAE1038 PAE3320
            PIS: Pisl_0566
            PCL: Pcal_1741
            PAS: Pars_1736
            CMA: Cmaq_0792
            TNE: Tneu_1556
            VDI: Vdis_1333
            NMR: Nmar_1258
            CSY: CENSYa_0943
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.95
            IUBMB Enzyme Nomenclature: 1.1.1.95
            ExPASy - ENZYME nomenclature database: 1.1.1.95
            BRENDA, the Enzyme Database: 1.1.1.95
            CAS: 9075-29-0
///
ENTRY       EC 1.1.1.96                 Enzyme
NAME        diiodophenylpyruvate reductase;
            aromatic alpha-keto acid;
            KAR;
            2-oxo acid reductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase
REACTION    3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ =
            3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + NADH + H+ [RN:R03431]
ALL_REAC    R03431
SUBSTRATE   3-(3,5-diiodo-4-hydroxyphenyl)lactate [CPD:C04367];
            NAD+ [CPD:C00003]
PRODUCT     3-(3,5-diiodo-4-hydroxyphenyl)pyruvate [CPD:C01244];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
COMMENT     Substrates contain an aromatic ring with a pyruvate side chain. The
            most active substrates are halogenated derivatives. Compounds with
            hydroxy or amino groups in the 3 or 5 position are inactive.
REFERENCE   1  [PMID:5935348]
  AUTHORS   Zannoni VG, Weber WW.
  TITLE     Isolation and properties of aromatic alpha-keto acid reductase.
  JOURNAL   J. Biol. Chem. 241 (1966) 1340-4.
  ORGANISM  Cavia porcellus
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.96
            IUBMB Enzyme Nomenclature: 1.1.1.96
            ExPASy - ENZYME nomenclature database: 1.1.1.96
            BRENDA, the Enzyme Database: 1.1.1.96
            CAS: 37250-31-0
///
ENTRY       EC 1.1.1.97                 Enzyme
NAME        3-hydroxybenzyl-alcohol dehydrogenase;
            m-hydroxybenzyl alcohol dehydrogenase;
            m-hydroxybenzyl alcohol (NADP+) dehydrogenase;
            m-hydroxybenzylalcohol dehydrogenase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     3-hydroxybenzyl-alcohol:NADP+ oxidoreductase
REACTION    3-hydroxybenzyl alcohol + NADP+ = 3-hydroxybenzaldehyde + NADPH + H+
            [RN:R04136]
ALL_REAC    R04136
SUBSTRATE   3-hydroxybenzyl alcohol [CPD:C03351];
            NADP+ [CPD:C00006]
PRODUCT     3-hydroxybenzaldehyde [CPD:C03067];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:4335290]
  AUTHORS   Forrester PI, Gaucher GM.
  TITLE     m-Hydroxybenzyl alcohol dehydrogenase from Penicillium urticae.
  JOURNAL   Biochemistry. 11 (1972) 1108-14.
  ORGANISM  Penicillium urticae
PATHWAY     ec00623  Toluene degradation
            ec01120  Microbial metabolism in diverse environments
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.97
            IUBMB Enzyme Nomenclature: 1.1.1.97
            ExPASy - ENZYME nomenclature database: 1.1.1.97
            BRENDA, the Enzyme Database: 1.1.1.97
            CAS: 9075-73-4
///
ENTRY       EC 1.1.1.98                 Enzyme
NAME        (R)-2-hydroxy-fatty-acid dehydrogenase;
            D-2-hydroxy fatty acid dehydrogenase;
            2-hydroxy fatty acid oxidase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (R)-2-hydroxystearate:NAD+ oxidoreductase
REACTION    (R)-2-hydroxystearate + NAD+ = 2-oxostearate + NADH + H+ [RN:R03021]
ALL_REAC    R03021
SUBSTRATE   (R)-2-hydroxystearate [CPD:C03042];
            NAD+ [CPD:C00003]
PRODUCT     2-oxostearate [CPD:C00869];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:5443694]
  AUTHORS   Levis GM.
  TITLE     2-Hydroxy fatty acid oxidases of rat kidney.
  JOURNAL   Biochem. Biophys. Res. Commun. 38 (1970) 470-7.
  ORGANISM  Rattus norvegicus [GN:rno]
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.98
            IUBMB Enzyme Nomenclature: 1.1.1.98
            ExPASy - ENZYME nomenclature database: 1.1.1.98
            BRENDA, the Enzyme Database: 1.1.1.98
            CAS: 37250-32-1
///
ENTRY       EC 1.1.1.99                 Enzyme
NAME        (S)-2-hydroxy-fatty-acid dehydrogenase;
            dehydrogenase, L-2-hydroxy fatty acid;
            L-2-hydroxy fatty acid dehydrogenase;
            2-hydroxy fatty acid oxidase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (S)-2-hydroxystearate:NAD+ oxidoreductase
REACTION    (S)-2-hydroxystearate + NAD+ = 2-oxostearate + NADH + H+ [RN:R03022]
ALL_REAC    R03022
SUBSTRATE   (S)-2-hydroxystearate [CPD:C03045];
            NAD+ [CPD:C00003]
PRODUCT     2-oxostearate [CPD:C00869];
            NADH [CPD:C00004];
            H+ [CPD:C00080]
REFERENCE   1  [PMID:5443694]
  AUTHORS   Levis GM.
  TITLE     2-Hydroxy fatty acid oxidases of rat kidney.
  JOURNAL   Biochem. Biophys. Res. Commun. 38 (1970) 470-7.
DBLINKS     ExplorEnz - The Enzyme Database: 1.1.1.99
            IUBMB Enzyme Nomenclature: 1.1.1.99
            ExPASy - ENZYME nomenclature database: 1.1.1.99
            BRENDA, the Enzyme Database: 1.1.1.99
            CAS: 37250-33-2
///
ENTRY       EC 1.1.1.100                Enzyme
NAME        3-oxoacyl-[acyl-carrier-protein] reductase;
            beta-ketoacyl-[acyl-carrier protein](ACP) reductase;
            beta-ketoacyl acyl carrier protein (ACP) reductase;
            beta-ketoacyl reductase;
            beta-ketoacyl thioester reductase;
            beta-ketoacyl-ACP reductase;
            beta-ketoacyl-acyl carrier protein reductase;
            3-ketoacyl acyl carrier protein reductase;
            NADPH-specific 3-oxoacyl-[acylcarrier protein]reductase;
            3-oxoacyl-[ACP]reductase;
            (3R)-3-hydroxyacyl-[acyl-carrier-protein]:NADP+ oxidoreductase
CLASS       Oxidoreductases;
            Acting on the CH-OH group of donors;
            With NAD+ or NADP+ as acceptor
SYSNAME     (3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase
REACTION    a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = a
            3-oxoacyl-[acyl-carrier protein] + NADPH + H+ [RN:R02767]
ALL_REAC    R02767 > R04533 R04534 R04536 R04543 R04566 R04953 R04964 R07763
SUBSTRATE   (3R)-3-hydroxyacyl-[acyl-carrier protein] [CPD:C01271];
            NADP+ [CPD:C00006]
PRODUCT     3-oxoacyl-[acyl-carrier protein] [CPD:C00685];
            NADPH [CPD:C00005];
            H+ [CPD:C00080]
COMMENT     Exhibits a marked preference for acyl-carrier-protein derivatives
            over CoA derivatives as substrates.
REFERENCE   1  [PMID:4561013]
  AUTHORS   Prescott DJ, Vagelos PR.
  TITLE     Acyl carrier protein.
  JOURNAL   Adv. Enzymol. Relat. Areas. Mol. Biol. 36 (1972) 269-311.
REFERENCE   2  [PMID:6756317]
  AUTHORS   Shimakata T, Stumpf PK.
  TITLE     Purification and characterizations of
            beta-Ketoacyl-[acyl-carrier-protein] reductase,
            beta-hydroxyacyl-[acylcarrier-protein] dehydrase, and
            enoyl-[acyl-carrier-protein] reductase from Spinacia oleracea
            leaves.
  JOURNAL   Arch. Biochem. Biophys. 218 (1982) 77-91.
  ORGANISM  Spinacia oleracea
REFERENCE   3  [PMID:4381013]
  AUTHORS   Toomey RE, Wakil SJ.
  TITLE     Studies on the mechanism of fatty acid synthesis. XV. Preparation
            and general properties of beta-ketoacyl acyl carrier protein
            reductase from Escherichia coli.
  JOURNAL   Biochim. Biophys. Acta. 116 (1966) 189-97.
  ORGANISM  Escherichia coli [GN:eco]
PATHWAY     ec00061  Fatty acid biosynthesis
            ec01040  Biosynthesis of unsaturated fatty acids
            ec01100  Metabolic pathways
ORTHOLOGY   K00059  3-oxoacyl-[acyl-carrier protein] reductase
            K11610  beta-ketoacyl ACP reductase
GENES       ATH: AT1G24360 AT1G63380 AT3G03980 AT3G04000 AT4G13180
            POP: POPTR_420605 POPTR_571216 POPTR_665443 POPTR_726104
                 POPTR_730005
            RCU: RCOM_1081890 RCOM_1121790 RCOM_1121800 RCOM_1121970
                 RCOM_1506940 RCOM_2133710
            VVI: 100241750 100246875 100254351 100257887
            OSA: 4329424 4334104 4335609 4340334 4342507 4343598 4348791 4351870
                 9270991
            SBI: SORBI_01g020280 SORBI_01g020300 SORBI_01g020310 SORBI_01g032550
                 SORBI_02g003960 SORBI_02g022080 SORBI_04g020450 SORBI_04g035770
                 SORBI_06g010860
            ZMA: 100273168(fab1) 100277126 100284513 100285342(umc2759)
                 100285462 100381348
            PPP: PHYPADRAFT_120696 PHYPADRAFT_187721
            CRE: CHLREDRAFT_114298 CHLREDRAFT_132065
            VCN: VOLCADRAFT_60269 VOLCADRAFT_79385
            OLU: OSTLU_12103
            OTA: Ot01g02200
            NCR: NCU07964 NCU09390 NCU09473
            PAN: PODANSg09804 PODANSg1142 PODANSg1466 PODANSg447 PODANSg8553
            MGR: MGG_02252(MG02252.4) MGG_06660(MG06660.4) MGG_07216(MG07216.4)
            FGR: FG03438.1 FG04045.1
            SSL: SS1G_06806 SS1G_10677 SS1G_12245 SS1G_13315
            BFU: BC1G_01850 BC1G_04040 BC1G_04230 BC1G_10858
            ANI: AN4934.2 AN6450.2 AN7806.2
            AFM: AFUA_1G14380 AFUA_2G17560 AFUA_3G10540 AFUA_7G04980
            NFI: NFIA_011040 NFIA_026060 NFIA_041110 NFIA_066740 NFIA_092980
                 NFIA_101580
            AOR: AO090003000520 AO090010000429 AO090011000370 AO090026000019
            ANG: An03g02840 An16g04520 An16g06450
            AFV: AFLA_000380 AFLA_032160 AFLA_033010 AFLA_042020 AFLA_119140
                 AFLA_139300
            ACT: ACLA_006690 ACLA_021040 ACLA_038440 ACLA_043650 ACLA_076470
            PCS: Pc13g10320 Pc16g12960 Pc21g16430 Pc21g17680
            CIM: CIMG_03191 CIMG_03599
            CPW: CPC735_006650 CPC735_009750
            URE: UREG_07375
            PNO: SNOG_08357 SNOG_10659 SNOG_11990
            PPL: POSPLDRAFT_101039
            LBC: LACBIDRAFT_306995
            MPR: MPER_03218
            CCI: CC1G_13586
            SCM: SCHCODRAFT_17565 SCHCODRAFT_56840 SCHCODRAFT_79125
            PFA: PFI1125c(fabG)
            PFD: PFDG_02160
            PFH: PFHG_01358
            PYO: PY02416
            PCB: PC000242.01.0
            PBE: PB000052.00.0
            PKN: PKH_072010
            PVX: PVX_099555
            TGO: TGME49_017740
            TBR: Tb927.2.5210
            TCR: 511627.150
            LMA: LmjF27.2440
            LIF: LinJ27.2070
            LBZ: LbrM27_V2.2650
            PTI: PHATRDRAFT_13073(FABG)
            TPS: THAPSDRAFT_270321
            ECO: b1093(fabG)
            ECJ: JW1079(fabG)
            ECD: ECDH10B_1165(fabG)
            EBW: BWG_0941(fabG)
            ECE: Z1732(fabG) Z4865(fabG)
            ECS: ECs1471(fabG) ECs4340(fabG)
            ECF: ECH74115_1472(fabG) ECH74115_4813(fabG)
            ETW: ECSP_1394(fabG) ECSP_4447(fabG)
            EOJ: ECO26_1426(fabG)
            EOI: ECO111_1370(fabG)
            EOH: ECO103_1138(fabG)
            ECG: E2348C_1185(fabG)
            EOK: G2583_1353(fabG) G2583_4194
            ECC: c1187(fabG)
            ECP: ECP_1085(fabG)
            ECI: UTI89_C1218(fabG)
            ECV: APECO1_174(fabG)
            ECX: EcHS_A1215(fabG)
            ECW: EcE24377A_1214(fabG)
            ECM: EcSMS35_2034(fabG)
            ECY: ECSE_1157(fabG)
            ECR: ECIAI1_1128(fabG)
            ECQ: ECED1_1236(fabG)
            ECK: EC55989_1205(fabG)
            ECT: ECIAI39_2068(fabG)
            EUM: ECUMN_1268(fabG) ECUMN_3954(fabG)
            ECZ: ECS88_1107(fabG)
            ECL: EcolC_2508(fabG)
            EBR: ECB_01089(fabG)
            EBD: ECBD_2508(fabG)
            EFE: EFER_0800 EFER_1834(fabG) EFER_3465(fabG)
            STY: STY1234(fabG)
            STT: t1725(fabG)
            STM: STM1195(fabG)
            SPT: SPA1656(fabG)
            SEK: SSPA1540(fabG)
            SPQ: SPAB_02328(fabG)
            SEI: SPC_2553(fabG)
            SEC: SC1143(fabG)
            SEH: SeHA_C1309(fabG)
            SEE: SNSL254_A1294(fabG)
            SEW: SeSA_A1265(fabG)
            SEA: SeAg_B1991(fabG)
            SED: SeD_A2174(fabG)
            SEG: SG1927(fabG)
            SET: SEN1854(fabG)
            SES: SARI_01803(fabG)
            YPE: YPO1456 YPO1599(fabG)
            YPK: y1758(fabG) y2713(fabG)
            YPA: YPA_0749 YPA_1926(fabG)
            YPN: YPN_2030(fabG) YPN_2522
            YPM: YP_1348(fabG6) YP_2255(fabG)
            YPP: YPDSF_1518 YPDSF_1848(fabG)
            YPG: YpAngola_A2968 YpAngola_A3499(fabG)
            YPZ: YPZ3_1327 YPZ3_2089(fabG)
            YPS: YPTB1474 YPTB2471(fabG)
            YPI: YpsIP31758_1578(fabG) YpsIP31758_2519
            YPY: YPK_1686(fabG) YPK_2609
            YPB: YPTS_1581 YPTS_2559(fabG)
            YEN: YE0798 YE0910(fabG) YE1635(fabG) YE2069
            SFL: SF1097(fabG)
            SFX: S1177(fabG)
            SFV: SFV_1113(fabG)
            SSN: SSON_1113(fabG)
            SBO: SBO_1970(fabG)
            SBC: SbBS512_E2231(fabG)
            SDY: SDY_2057(fabG)
            ECA: ECA1209 ECA1797(fabG) ECA4492(fabG)
            PCT: PC1_2503
            PWA: Pecwa_2808(fabG) Pecwa_4581(fabG)
            ETA: ETA_20220(fabG) ETA_30050
            EPY: EpC_21480(fabG)
            EAM: EAMY_1474(fabG)
            EAY: EAM_1458(fabG)
            EBI: EbC_10680 EbC_10690 EbC_16020 EbC_16550(fabG) EbC_21520
                 EbC_34960
            PLU: plu1541 plu2833(fabG) plu4678
            PAY: PAU_01704(fabG) PAU_02901 PAU_04158(fabG)
            BUC: BU351(fabG)
            BAS: BUsg339(fabG)
            BAB: bbp321(fabG)
            BCC: BCc_217(fabG)
            BAP: BUAP5A_344(fabG)
            BAU: BUAPTUC7_345(fabG)
            WBR: WGLp091(fabG)
            SGL: SG1060
            ENT: Ent638_1608(fabG) Ent638_2516 Ent638_3898(fabG)
            ENC: ECL_00386 ECL_02543 ECL_03797 ECL_04854
            ESC: Entcl_0256 Entcl_2700
            ESA: ESA_01294 ESA_02252(fabG)
            CTU: Ctu_16720(fabG) Ctu_26320 Ctu_40030(fabG)
            KPN: KPN_01091(fabG) KPN_01694(fabG)
            KPE: KPK_2230 KPK_2307 KPK_3284 KPK_3465(fabG)
            KPU: KP1_2082(fabG) KP1_2746(fabG)
            KVA: Kvar_3152 Kvar_3289
            CKO: CKO_01965(fabG) CKO_04923(fabG)
            CRO: ROD_11551(fabG) ROD_35141 ROD_43261
            SPE: Spro_0127 Spro_0623 Spro_0642 Spro_0902(fabG) Spro_1404
                 Spro_1906(fabG) Spro_3727 Spro_3866 Spro_4437
            PMR: PMI0861(fabG) PMI3202
            EIC: NT01EI_2369(fabG) NT01EI_2713
            ETR: ETAE_0824(fabG1) ETAE_2099(fabG2) ETAE_2407(fabG3)
            BFL: Bfl404(fabG)
            BPN: BPEN_416(fabG)
            BVA: BVAF_407(fabG)
            HDE: HDEF_0447(fabG)
            DDA: Dd703_1587 Dd703_1811
            DDC: Dd586_1266 Dd586_1586 Dd586_1861 Dd586_4180
            DDD: Dda3937_03279 Dda3937_04626(fabG)
            DZE: Dd1591_1623 Dd1591_2838
            XBO: XBJ1_1403 XBJ1_2859(fabG)
            XNE: XNC1_1173(fabG) XNC1_2735(fabG) XNC1_3583
            PAM: PANA_0563(fabG) PANA_1483(fabG) PANA_1932(fabG)
            PVA: Pvag_0846(fabG2) Pvag_0894(fabg1) Pvag_3686
            PAO: Pat9b_0515 Pat9b_1482 Pat9b_1844 Pat9b_2945 Pat9b_5550
                 Pat9b_5632 Pat9b_5633
            RIP: RIEPE_0396
            HIN: HI0155(fabG)
            HIT: NTHI0244(fabG)
            HIP: CGSHiEE_02510(fabG)
            HIQ: CGSHiGG_03370(fabG)
            HIF: HIBPF19790
            HIL: HICON_13180
            HDU: HD0708(fabG)
            HAP: HAPS_0854(fabG)
            HSO: HS_0107(fabG) HS_0167(fabG)
            HSM: HSM_0034(fabG) HSM_1992(fabG)
            PMU: PM1916(fabG)
            MSU: MS1874(fabG)
            APL: APL_1992(fabG)
            APJ: APJL_2040(fabG)
            APA: APP7_2079(fabG)
            ASU: Asuc_2001(fabG)
            AAP: NT05HA_1504(fabG) NT05HA_1717(fabG)
            AAT: D11S_0526(fabG) D11S_2151(fabG)
            XFA: XF0173(fabG) XF0671(fabG)
            XFT: PD0141(fabG) PD1503(fabG)
            XFM: Xfasm12_0146(fabG) Xfasm12_1645(fabG)
            XFN: XfasM23_0129(fabG) XfasM23_1588(fabG)
            XCC: XCC0384 XCC0416 XCC1018(fabG) XCC4003(fabG)
            XCB: XC_0396 XC_0429 XC_3227(fabG) XC_4092(fabG)
            XCA: xccb100_0411 xccb100_3340(fabG) xccb100_4196(fabG)
            XCV: XCV0060 XCV0399 XCV0459 XCV1146(fabG) XCV4178(fabG)
            XAC: XAC0083 XAC0384 XAC0433 XAC1127(fabG) XAC4090(fabG)
            XOO: XOO0234 XOO0459(fabG) XOO0881(fabG)
            XOM: XOO_0214 XOO_0422(fabG) XOO_0806(fabG)
            XOP: PXO_02709(fabG) PXO_02878(fabG) PXO_03629
            XAL: XALc_0137 XALc_0351 XALc_0626(fabG)
            SML: Smlt1029(fabG) Smlt2131 Smlt2216(fabG) Smlt2696 Smlt3653
                 Smlt4462 Smlt4557(fabG)
            SMT: Smal_0872(fabG) Smal_1707 Smal_1727 Smal_1809(fabG) Smal_2069
                 Smal_2168 Smal_3069 Smal_3830 Smal_3909
            PSU: Psesu_1574 Psesu_2003 Psesu_2788
            VCH: VC2021(fabG)
            VCO: VC0395_A1607(fabG)
            VCM: VCM66_1945(fabG)
            VCJ: VCD_002346(fabG)
            VVU: VV1_0060(fabG) VV1_3009(fabG) VV2_0488(fabG)
            VVY: VV1067(fabG) VV1275(fabG) VVA1037(fabG)
            VVM: VVM_01989 VVM_03524 VVM_03742
            VPA: VP0882(fabG) VP2054(fabG) VPA0626(fabG) VPA1117(fabG) VPA1304
            VHA: VIBHAR_02553 VIBHAR_02908(fabG) VIBHAR_05488(fabG) VIBHAR_06461
            VSP: VS_0771(fabG) VS_1024(fabG)
            VEX: VEA_000369 VEA_000603 VEA_001551 VEA_002996 VEA_003354
                 VEA_004077
            VFI: VF_0859(fabG) VF_1740(fabG)
            VFM: VFMJ11_0897(fabG) VFMJ11_1867(fabG)
            VSA: VSAL_I2090(fabG) VSAL_I2241(fabG) VSAL_p840_70
            PPR: PBPRA1195(fabG) PBPRB0105(fabG) PBPRB1106(fabG) PBPRB1562
            PAE: PA0182 PA1470 PA1827 PA2967(fabG) PA4089 PA4389(speA) PA4786
                 PA5524
            PAU: PA14_02300(fabG) PA14_11020(fabG) PA14_25660(fabG) PA14_40900
                 PA14_45430 PA14_57050(fabG) PA14_63270(fabG) PA14_72880(fabG)
            PAP: PSPA7_0262(fabG) PSPA7_1010 PSPA7_2194(fabG) PSPA7_3469
                 PSPA7_3856 PSPA7_4960(fabG) PSPA7_5508(fabG) PSPA7_6325
            PAG: PLES_01831(fabG) PLES_08871 PLES_20961(fabG) PLES_35001
                 PLES_39431 PLES_47681(fabG) PLES_59201
            PPU: PP_0581(fabG) PP_1852(fabG) PP_1914(fabG) PP_2540 PP_2783
            PPF: Pput_0620(fabG) Pput_2199 Pput_3177 Pput_3800(fabG)
                 Pput_3860(fabG)
            PPG: PputGB1_0626(fabG) PputGB1_1428(fabG) PputGB1_1490(fabG)
                 PputGB1_1794 PputGB1_2024 PputGB1_2211 PputGB1_2345
            PPW: PputW619_1463(fabG) PputW619_1525(fabG) PputW619_1689(fabG)
                 PputW619_2844 PputW619_4583(fabG)
            PST: PSPTO_0743 PSPTO_2097 PSPTO_3832(fabG) PSPTO_4380 PSPTO_5109
            PSB: Psyr_0423(fabG) Psyr_0644(fabG) Psyr_1647(fabG) Psyr_1892(fabG)
                 Psyr_3542 Psyr_4075(fabG)
            PSP: PSPPH_0413(fabG) PSPPH_1641(fabG) PSPPH_1847(fabG)
                 PSPPH_4080(fabG) PSPPH_4651(fabG)
            PFL: PFL_0252(fabG) PFL_0462(fabG) PFL_0705(fabG) PFL_1364(fabG)
                 PFL_1796(fabG) PFL_1850(fabG) PFL_2940(fabG) PFL_3223(fabG-2)
                 PFL_3647(fabG) PFL_4842(fabG)
            PFO: Pfl01_0423(fabG) Pfl01_0655(fabG) Pfl01_1753(fabG)
                 Pfl01_4157(fabG) Pfl01_4505(fabG)
            PFS: PFLU0421(fabG) PFLU0654(fabG) PFLU1075 PFLU1076 PFLU1988
                 PFLU3067 PFLU3194 PFLU3283 PFLU3528(fabG) PFLU4646(fabG)
                 PFLU4705(fabG)
            PEN: PSEEN0346(fabG) PSEEN0663(fabG) PSEEN1557(fabG) PSEEN1618(fabG)
                 PSEEN2587 PSEEN3111
            PMY: Pmen_0744(fabG) Pmen_1628(fabG) Pmen_3684(fabG)
            PSA: PST_2622(fabG) PST_3149(fabG)
            CJA: CJA_0116 CJA_1676(fabG)
            AVN: Avin_06560 Avin_13430(fabG) Avin_14920(fabG) Avin_16730
            PAR: Psyc_0521(fabG) Psyc_1309(fabG) Psyc_1871
            PCR: Pcryo_0516 Pcryo_1069(fabG) Pcryo_2161
            PRW: PsycPRwf_0457 PsycPRwf_1389(fabG)
            ACI: ACIAD0582(fabG) ACIAD0871(fabG) ACIAD1976(fabG)
            ACD: AOLE_06920(fabG) AOLE_08550 AOLE_11635 AOLE_15575 AOLE_16810
            ACB: A1S_0524 A1S_0818 A1S_1409 A1S_1858 A1S_2061(fabG)
            ABM: ABSDF2213(fabG) ABSDF2640(fabG)
            ABY: ABAYE1514(fabG) ABAYE1706 ABAYE2246 ABAYE2992(fabG)
            ABC: ACICU_00533(fabG) ACICU_00776 ACICU_01449 ACICU_01970
                 ACICU_02253(fabG)
            ABN: AB57_0871(fabG) AB57_1642 AB57_2193 AB57_2382(fabG)
            ABB: ABBFA_001415(fabG) ABBFA_001594 ABBFA_002078 ABBFA_002794(fabG)
            MCT: MCR_0461 MCR_1553(fabG)
            SON: SO_1683(fabG) SO_2776(fabG-1) SO_2813(fabG) SO_4382(fabG)
            SDN: Sden_1937(fabG) Sden_2293 Sden_3106
            SFR: Sfri_0338(fabG) Sfri_1344(fabG) Sfri_1499
            SAZ: Sama_1381(fabG) Sama_1980 Sama_3393(fabG)
            SBL: Sbal_0328(fabG) Sbal_1501(fabG) Sbal_1719 Sbal_2960
            SBM: Shew185_0326(fabG) Shew185_1495(fabG) Shew185_1716
                 Shew185_4227(fabG)
            SBN: Sbal195_0333(fabG) Sbal195_1531(fabG) Sbal195_1759
                 Sbal195_4359(fabG)
            SBP: Sbal223_0336(fabG) Sbal223_1403 Sbal223_2573 Sbal223_2850(fabG)
                 Sbal223_4155(fabG)
            SLO: Shew_1322 Shew_1603 Shew_1673(fabG) Shew_3525(fabG)
            SPC: Sputcn32_0112(fabG) Sputcn32_0432(fabG) Sputcn32_1403(fabG)
                 Sputcn32_1582
            SSE: Ssed_0311(fabG) Ssed_1479(fabG) Ssed_2624 Ssed_3534
            SPL: Spea_2148 Spea_2168 Spea_2494 Spea_2777(fabG) Spea_3902(fabG)
            SHE: Shewmr4_0336(fabG) Shewmr4_2396 Shewmr4_2591(fabG)
            SHM: Shewmr7_2466 Shewmr7_2658(fabG) Shewmr7_3690(fabG)
            SHN: Shewana3_0327(fabG) Shewana3_2558 Shewana3_2765(fabG)
            SHW: Sputw3181_0286(fabG) Sputw3181_2440 Sputw3181_2698(fabG)
            SHL: Shal_0367(fabG) Shal_1401 Shal_1777 Shal_2119 Shal_2139
                 Shal_2747 Shal_2872(fabG)
            SWD: Swoo_2042 Swoo_3196(fabG) Swoo_4611(fabG)
            SWP: swp_0289(fabG) swp_3045 swp_3381(fabG)
            SVO: SVI_2543(fabG-1) SVI_3097 SVI_4106(fabG-2)
            ILO: IL0142(fabG) IL0866(fabG) IL1340(fabG)
            CPS: CPS_0665 CPS_1608(fabG) CPS_2297(fabG)
            PHA: PSHAa0894 PSHAa1460(fabG) PSHAa1808(fabG) PSHAa2151
                 PSHAb0409(fabG)
            PAT: Patl_0769 Patl_0952(fabG) Patl_2122 Patl_3071 Patl_4046
            PSM: PSM_A0446 PSM_A1251(fabG) PSM_A1505(fabG)
            SDE: Sde_1629
            MAQ: Maqu_1867 Maqu_2017(fabG) Maqu_2033(fabG)
            PIN: Ping_1089
            TTU: TERTU_1720(fabG) TERTU_3288
            FBL: Fbal_1024 Fbal_1397
            CBU: CBU_0495(fabG) CBU_0702 CBU_1514
            CBS: COXBURSA331_A0604(fabG) COXBURSA331_A0820
            CBD: CBUD_0470 CBUD_0716 CBUD_1581(fabG)
            CBG: CbuG_1300 CbuG_1518(fabG)
            CBC: CbuK_1363(fabG) CbuK_1552
            LPN: lpg1395(fabG) lpg2231(fabG)
            LPF: lpl1346(fabG) lpl2157
            LPP: lpp1350(fabG) lpp2184
            LPC: LPC_0811 LPC_1699(fabG)
            LPA: lpa_02052 lpa_03207 lpa_03407
            LLO: LLO_1483(fabG) LLO_2608(fabG)
            MCA: MCA0927(fabG) MCA2001(fabG)
            FTU: FTT_1375(fabG)
            FTF: FTF1375(fabG)
            FTW: FTW_0516(fabG)
            FTL: FTL_1139
            FTH: FTH_1114(fabG)
            FTA: FTA_1202(fabG)
            FTM: FTM_0648(fabG)
            FTN: FTN_1339(fabG)
            FPH: Fphi_1092 Fphi_1349
            TCX: Tcr_0712
            NOC: Noc_1665
            NHL: Nhal_1378 Nhal_3117 Nhal_3411
            NWA: Nwat_1460
            ALV: Alvin_1891
            AEH: Mlg_1421
            HHA: Hhal_1233
            TGR: Tgr7_0904 Tgr7_1835
            TKM: TK90_0472 TK90_1259
            HNA: Hneap_1924 Hneap_2241
            HCH: HCH_00126 HCH_02144(fabG) HCH_04617(fabG) HCH_05141(fabG)
            CSA: Csal_0785(fabG) Csal_1601 Csal_1758 Csal_2157(fabG)
                 Csal_2760(fabG)
            HEL: HELO_1998(fabG) HELO_2872(fabG) HELO_2903(fabG)
            ABO: ABO_0632(fabG) ABO_1069(fabG) ABO_1713(fabG)
            KKO: Kkor_0388 Kkor_1188 Kkor_2588
            MMW: Mmwyl1_1828 Mmwyl1_2132 Mmwyl1_3887(fabG) Mmwyl1_4168
            AHA: AHA_2084(fabG) AHA_2251(fabG) AHA_3383(fabG)
            ASA: ASA_0429(fabG) ASA_0924(fabG) ASA_1918(fabG) ASA_2054(fabG)
            TAU: Tola_2192
            DNO: DNO_0531 DNO_1209(fabG)
            AFE: Lferr_0936(fabG) Lferr_1583
            AFR: AFE_0793(fabG) AFE_1908(fabG)
            BCI: BCI_0434(fabG)
            RMA: Rmag_0916
            VOK: COSY_0822(fabG)
            GPB: HDN1F_02490 HDN1F_24740(fabG1) HDN1F_28110 HDN1F_32070(fabG2)
                 HDN1F_33300 HDN1F_35690
            NMA: NMA0533(fabG)
            NME: NMB1702(fabG) NMB1921(fabG)
            NMC: NMC0302(fabG)
            NMN: NMCC_0298(fabG)
            NMI: NMO_0250(fabG)
            NGO: NGO2163(fabG)
            NGK: NGK_1582(fabG) NGK_2642(fabG)
            NLA: NLA_18670(fabG) NLA_5790(fabG-1)
            CVI: CV_1546 CV_3414(fabG) CV_3576(fabG2) CV_3947
            LHK: LHK_00570(fabG) LHK_00699(fabG2)
            RSO: RS05466(RSp0305) RSc0435(fabG) RSc0536(fabG) RSc1052(fabG)
                 RSc2186 RSc2351(fabG) RSp0359(fabG)
            RSC: RCFBP_11080 RCFBP_11210(fabG) RCFBP_20426(fabG)
                 RCFBP_20940(fabG) RCFBP_21049(fabG)
            RSL: RPSI07_1121 RPSI07_1237(fabG) RPSI07_2341(fabG)
                 RPSI07_2823(fabG) RPSI07_2936(fabG) RPSI07_mp0286(fabG)
            RPI: Rpic_0416(fabG) Rpic_0917(fabG) Rpic_2383 Rpic_2567(fabG)
                 Rpic_4773(fabG) Rpic_4824
            RPF: Rpic12D_0431(fabG) Rpic12D_0982(fabG) Rpic12D_1983
                 Rpic12D_2162(fabG) Rpic12D_3696(fabG) Rpic12D_3747
            REU: Reut_A1570 Reut_A1622 Reut_A2263(fabG) Reut_A2505
                 Reut_A2616(fabG) Reut_A2858 Reut_B3486 Reut_B3848 Reut_B3871
                 Reut_B3935(fabG) Reut_B4170 Reut_B4557 Reut_B4754 Reut_C6224
                 Reut_C6276 Reut_C6315 Reut_C6404
            REH: H16_A0743(fabG) H16_A0849 H16_A0931 H16_A1287 H16_A2567(fabG)
                 H16_A3164 H16_B0101 H16_B0361 H16_B0385 H16_B0666 H16_B1075
                 H16_B1798 H16_B1834(fabG) H16_B1904 H16_B2510(fabG)
            RME: Rmet_0675(fabG) Rmet_0791 Rmet_1911 Rmet_2428 Rmet_2526
                 Rmet_2533 Rmet_3057 Rmet_3874 Rmet_4391(fabG) Rmet_4544
                 Rmet_5028(fabG) Rmet_5524 Rmet_5825
            CTI: RALTA_A0729(fabG) RALTA_A0876 RALTA_A2070(fabG1) RALTA_A2639
                 RALTA_B0508 RALTA_B2239(fabG)
            BMA: BMA0532(fabG) BMA0734(fabG) BMA1882 BMAA0644 BMAA1104 BMAA1367
            BMV: BMASAVP1_0103 BMASAVP1_0352 BMASAVP1_A1078 BMASAVP1_A2279(fabG)
                 BMASAVP1_A2477(fabG)
            BML: BMA10229_0321 BMA10229_0631 BMA10229_0820 BMA10229_A0789
                 BMA10229_A2804(fabG) BMA10229_A3005(fabG)
            BMN: BMA10247_0361 BMA10247_1592(fabG) BMA10247_1800(fabG)
                 BMA10247_A0940 BMA10247_A1272 BMA10247_A1782
            BPS: BPSL1019(fabG) BPSL1167 BPSL2440(fabG) BPSS0794 BPSS0866
                 BPSS1256
            BPM: BURPS1710b_1234(fabG) BURPS1710b_1388 BURPS1710b_2905(fabG)
                 BURPS1710b_A0256 BURPS1710b_A2378 BURPS1710b_A2464
            BPL: BURPS1106A_1082(fabG) BURPS1106A_1243 BURPS1106A_2851(fabG)
                 BURPS1106A_A1085 BURPS1106A_A1197 BURPS1106A_A1687
            BPD: BURPS668_1076(fabG) BURPS668_1234 BURPS668_2790(fabG)
                 BURPS668_A1162 BURPS668_A1271 BURPS668_A1775
            BPR: GBP346_A1074(fabG) GBP346_A1260 GBP346_A2971(fabG)
            BTE: BTH_I0876(fabG) BTH_I1017 BTH_I1719(fabG) BTH_II0319 BTH_II1155
                 BTH_II1539 BTH_II1602
            BVI: Bcep1808_1042(fabG) Bcep1808_1382 Bcep1808_2377
                 Bcep1808_2505(fabG) Bcep1808_2562 Bcep1808_2863 Bcep1808_3383
                 Bcep1808_5966(fabG)
            BUR: Bcep18194_A4235(fabG) Bcep18194_A4562 Bcep18194_A4911
                 Bcep18194_A5619 Bcep18194_A5746(fabG) Bcep18194_A5811
                 Bcep18194_A6088(fabG) Bcep18194_B0623 Bcep18194_B0903
                 Bcep18194_B1002 Bcep18194_B1189 Bcep18194_B1443 Bcep18194_B2504
                 Bcep18194_B3095 Bcep18194_C6694 Bcep18194_C6740 Bcep18194_C6936
                 Bcep18194_C7112 Bcep18194_C7276 Bcep18194_C7331
            BCN: Bcen_0643(fabG) Bcen_0936 Bcen_1680 Bcen_1807(fabG) Bcen_1868
                 Bcen_2144 Bcen_3327 Bcen_3566 Bcen_3619
            BCH: Bcen2424_1123(fabG) Bcen2424_1418 Bcen2424_2292
                 Bcen2424_2419(fabG) Bcen2424_2479 Bcen2424_2758 Bcen2424_3611
                 Bcen2424_4748 Bcen2424_4801 Bcen2424_5040
            BCM: Bcenmc03_1081(fabG) Bcenmc03_1396 Bcenmc03_2315
                 Bcenmc03_2423(fabG) Bcenmc03_2504 Bcenmc03_3909 Bcenmc03_5244
                 Bcenmc03_5482 Bcenmc03_5535
            BCJ: BCAL0846 BCAL0994(fabG) BCAL1151 BCAL1425 BCAL2386
                 BCAL2624(fabG) BCAL2689 BCAM0640 BCAM1625 BCAM1949 BCAM2001
                 BCAM2283
            BAM: Bamb_0999(fabG) Bamb_1298 Bamb_2330 Bamb_2464(fabG) Bamb_2528
                 Bamb_2810 Bamb_3610 Bamb_4131 Bamb_4181 Bamb_4448 Bamb_5347
                 Bamb_6431
            BAC: BamMC406_1003(fabG) BamMC406_1205 BamMC406_1337 BamMC406_2208
                 BamMC406_2329(fabG) BamMC406_2399 BamMC406_2677 BamMC406_3517
                 BamMC406_4085 BamMC406_4595 BamMC406_4634 BamMC406_4703
                 BamMC406_4968
            BMU: Bmul_0815 Bmul_0873(fabG) Bmul_0986 Bmul_1897 Bmul_2181(fabG)
                 Bmul_3598 Bmul_3804 Bmul_3928 Bmul_5087
            BMJ: BMULJ_01060(fabG) BMULJ_01344(fabG) BMULJ_02278(fabG)
                 BMULJ_02385(fabG) BMULJ_02445(fabG) BMULJ_03429
                 BMULJ_04573(fabG) BMULJ_04714(fabG) BMULJ_04919(fabG)
            BXE: Bxe_A0939 Bxe_A1074(fabG) Bxe_A2099 Bxe_A2114 Bxe_A2692
                 Bxe_A2719 Bxe_A2775(fabG) Bxe_A3012 Bxe_A3257 Bxe_A3402(fabG)
                 Bxe_B0266 Bxe_B1028 Bxe_B2157 Bxe_B2694 Bxe_B2728 Bxe_C0296
                 Bxe_C0589 Bxe_C0591 Bxe_C0616 Bxe_C0900
            BPH: Bphy_0342 Bphy_0702 Bphy_0830(fabG) Bphy_1701(fabG) Bphy_2062
                 Bphy_2175(fabG) Bphy_3470 Bphy_4948(fabG) Bphy_5382 Bphy_5822
                 Bphy_6096 Bphy_6716 Bphy_7447
            BPY: Bphyt_0979 Bphyt_1094(fabG) Bphyt_1303 Bphyt_1428
                 Bphyt_1675(fabG) Bphyt_2144 Bphyt_2165 Bphyt_2910(fabG)
                 Bphyt_3052 Bphyt_4455(fabG) Bphyt_5691 Bphyt_6446
            BGL: bglu_1g09530(fabG) bglu_1g14800 bglu_1g17980 bglu_1g26330
                 bglu_1g27890(fabG) bglu_2g00890 bglu_2g07900 bglu_2g19380
            BGE: BC1002_0791 BC1002_0914 BC1002_1052 BC1002_1216 BC1002_1615
                 BC1002_2141 BC1002_2267 BC1002_4239 BC1002_5128 BC1002_5397
                 BC1002_6020 BC1002_6574
            BRH: RBRH_02491 RBRH_02617
            PNU: Pnuc_0214 Pnuc_0400 Pnuc_1069
            PNE: Pnec_0235 Pnec_0407
            BPE: BP0466(fabG) BP0772(fabG) BP0813 BP0859(fabG) BP1128(fabG)
                 BP1668 BP1672(fabG) BP1785(fabG) BP2441(fabG) BP2554(fabG)
                 BP3010
            BPA: BPP0333(fabG) BPP0607 BPP1392 BPP2016(fabG) BPP2100
                 BPP2625(fabG) BPP3213(fabG) BPP3305(fabG) BPP3372(fabG) BPP3417
                 BPP3739 BPP4380(fabG)
            BBR: BB0336(fabG) BB0613 BB1496 BB2068(fabG) BB2264(fabG) BB2461
                 BB3665(fabG) BB3756(fabG) BB3823(fabG) BB3867 BB4185 BB4686
                 BB4764(fabG) BB4780 BB4966(fabG)
            BPT: Bpet1755(fabG) Bpet1965 Bpet3662 Bpet3787 Bpet4167
                 Bpet4438(fabG)
            BAV: BAV0212 BAV0488(fabG) BAV0642 BAV0684 BAV1121(fabG) BAV3257
                 BAV3386(fabG)
            AXY: AXYL_00259(fabG1) AXYL_00540(phbB1) AXYL_00804
                 AXYL_01547(fabG2) AXYL_01697(fabG3) AXYL_02346(fabG5)
                 AXYL_02490 AXYL_02609 AXYL_02888 AXYL_03433(fabG7) AXYL_03872
                 AXYL_04787 AXYL_04869 AXYL_04943(fabG8) AXYL_05472(fabG9)
                 AXYL_05809 AXYL_05924 AXYL_06098
            TEQ: TEQUI_1099
            RFR: Rfer_1638 Rfer_1732 Rfer_3136 Rfer_3195 Rfer_3586(fabG)
                 Rfer_3994(fabG) Rfer_4047
            POL: Bpro_0092(fabG) Bpro_1491 Bpro_2289(fabG) Bpro_3307(fabG)
                 Bpro_3647 Bpro_3876 Bpro_3960 Bpro_4767
            PNA: Pnap_1368(fabG) Pnap_2307 Pnap_3072 Pnap_3235 Pnap_3989
            AAV: Aave_1080 Aave_1185 Aave_2660(fabG) Aave_4512
            AJS: Ajs_3278 Ajs_3977(fabG)
            DIA: Dtpsy_2631 Dtpsy_2744 Dtpsy_3330(fabG)
            VEI: Veis_0638 Veis_0666(fabG) Veis_0996 Veis_1551 Veis_3005(fabG)
                 Veis_3250 Veis_3854 Veis_4114
            DAC: Daci_2089 Daci_2090 Daci_2285 Daci_4525 Daci_4884(fabG)
                 Daci_5270 Daci_5391
            VAP: Vapar_0789 Vapar_1256 Vapar_1391 Vapar_1509 Vapar_1720
                 Vapar_2678(fabG) Vapar_4308 Vapar_5033 Vapar_5322 Vapar_5496
                 Vapar_5771
            VPE: Varpa_0812 Varpa_1351 Varpa_1438 Varpa_1532 Varpa_1891
                 Varpa_2256 Varpa_2639 Varpa_2640 Varpa_3230 Varpa_3776
                 Varpa_5743
            CTT: CtCNB1_0855 CtCNB1_0972 CtCNB1_1271 CtCNB1_1289 CtCNB1_1295
                 CtCNB1_1711 CtCNB1_1924 CtCNB1_2068
            ADN: Alide_1161 Alide_1814 Alide_2937 Alide_2952 Alide_3184
                 Alide_3302 Alide_4196
            MPT: Mpe_A0638 Mpe_A1327(fabG) Mpe_A3053
            HAR: HEAR0567 HEAR2075(fabG) HEAR2870(fabG)
            MMS: mma_0550 mma_1358(fabG) mma_1860 mma_2018
            HSE: Hsero_1047 Hsero_1263(fabG) Hsero_1348(fabG) Hsero_1925(fabG)
                 Hsero_2253(tsaC) Hsero_2803(fabG) Hsero_3315(phaB)
                 Hsero_3715(fabG) Hsero_3897
            LCH: Lcho_0609 Lcho_1226 Lcho_3979
            TIN: Tint_2390 Tint_2531
            NEU: NE1648(fabG1)
            NET: Neut_0468
            NMU: Nmul_A1074 Nmul_A1378
            EBA: ebA5300(bzdZ) ebA5457(fabG) ebA5789(ped2) ebA7075(fabG)
            AZO: azo1625(fabG) azo3914(fabG)
            DAR: Daro_2017 Daro_4188(fabG)
            TMZ: Tmz1t_2326(fabG) Tmz1t_2944
            TBD: Tbd_1549 Tbd_2756(fabG)
            MFA: Mfla_1505 Mfla_1785(fabG) Mfla_2669
            MMB: Mmol_1143
            MEH: M301_0671 M301_1337 M301_2323
            MEI: Msip34_1386 Msip34_1415 Msip34_2478
            MEP: MPQ_1460 MPQ_1488 MPQ_2424
            APP: CAP2UW1_0365(fabG) CAP2UW1_1538 CAP2UW1_2694
            SLT: Slit_0353 Slit_1530
            GCA: Galf_1551
            HPY: HP0561(fabG)
            HPJ: jhp0508(fabG)
            HPA: HPAG1_0540(fabG)
            HPS: HPSH_04070(fabG)
            HPG: HPG27_520(fabG)
            HPP: HPP12_0567(fabG)
            HPB: HELPY_0816(fabG)
            HPL: HPB8_756(fabG)
            HPC: HPPC_02780(fabG)
            HPM: HPSJM_02840(fabG)
            HHE: HH0092 HH0732(fabG)
            HAC: Hac_0781(fabG)
            HMS: HMU11980(fabG)
            HFE: Hfelis_04020(fabG)
            WSU: WS0631(fabG)
            TDN: Suden_1613(fabG)
            SKU: Sulku_0363
            CJE: Cj0435(fabG) Cj0485
            CJR: CJE0485(fabG) CJE0535
            CJJ: CJJ81176_0461(fabG)
            CJU: C8J_0410(fabG)
            CJD: JJD26997_1425 JJD26997_1449 JJD26997_1509(fabG)
            CFF: CFF8240_1065 CFF8240_1361(fabG)
            CCV: CCV52592_1043(fabG) CCV52592_1164
            CHA: CHAB381_0231(fabG)
            CCO: CCC13826_0562(fabG)
            CLA: Cla_0269(fabG)
            ABU: Abu_2058(fabG)
            ANT: Arnit_0497 Arnit_0850 Arnit_2322
            SDL: Sdel_1837 Sdel_2101
            NIS: NIS_0313(fabG)
            SUN: SUN_2189(fabG)
            NSA: Nitsa_0489
            NAM: NAMH_0292(fabG) NAMH_1600
            GSU: GSU0461(fabG-1) GSU1603(fabG-2)
            GME: Gmet_1601 Gmet_1694 Gmet_2059
            GUR: Gura_1536 Gura_1877 Gura_3607
            GLO: Glov_1936 Glov_2194
            GBM: Gbem_3106(fabG-2)
            GEO: Geob_0099 Geob_1910 Geob_2614
            GEM: GM21_1156
            PCA: Pcar_1438(fabG) Pcar_2667
            PPD: Ppro_0905 Ppro_1518 Ppro_1744
            DVU: DVU1206(fabG) DVU2561 DVU3137(fabG)
            DVL: Dvul_0249(fabG) Dvul_0687 Dvul_1851
            DVM: DvMF_1004 DvMF_2858 DvMF_3100
            DDE: Dde_2429 Dde_2658
            DDS: Ddes_1614
            DMA: DMR_22790 DMR_39960(fabG)
            DSA: Desal_0541 Desal_0576 Desal_0660
            DAS: Daes_2796
            LIP: LI0161(fabG) LI0419
            DBA: Dbac_0067 Dbac_1122
            DRT: Dret_1415
            BBA: Bd0281(fabG) Bd0405(fabG) Bd0506 Bd2012(fabG)
            DPS: DP1847 DP2407 DP2790
            DAK: DaAHT2_1120 DaAHT2_1286
            DPR: Despr_2011 Despr_2665
            DOL: Dole_1608 Dole_2084
            DAL: Dalk_3307 Dalk_3912 Dalk_4854(fabG)
            DAT: HRM2_25710(fabG4) HRM2_25940(fabG5)
            ADE: Adeh_2748 Adeh_2760 Adeh_3141
            ACP: A2cp1_2743 A2cp1_2932 A2cp1_2944 A2cp1_3331 A2cp1_3385
            AFW: Anae109_2033 Anae109_2552 Anae109_2737 Anae109_3255
                 Anae109_3601 Anae109_4404
            ANK: AnaeK_2649 AnaeK_2840 AnaeK_2852 AnaeK_3245
            MXA: MXAN_0211 MXAN_0915 MXAN_4770(fabG)
            SCL: sce1646(fabG3) sce3273 sce3354(fabG7) sce3815 sce5302(fabG10)
            HOH: Hoch_0481 Hoch_5001 Hoch_5030 Hoch_5197 Hoch_5651
            SAT: SYN_01680 SYN_01696 SYN_02127
            SFU: Sfum_0112 Sfum_1374
            DBR: Deba_1430 Deba_2388
            RPR: RP762(fabG)
            RTY: RT0748(fabG)
            RCM: A1E_04870(fabG)
            RCO: RC1183(fabG)
            RFE: RF_1222(fabG)
            RAK: A1C_05935(fabG)
            RRI: A1G_06495(fabG)
            RRJ: RrIowa_1392
            RMS: RMA_1204(fabG)
            RPK: RPR_03080(fabG)
            RAF: RAF_ORF1078(fabG)
            RBE: RBE_0116(fabG)
            RBO: A1I_07350(fabG)
            OTS: OTBS_0381(fabG)
            OTT: OTT_1039(fabG)
            WOL: WD0650(fabG)
            WBM: Wbm0310
            WRI: WRi_004870(fabG)
            WPI: WPa_1198(fabG)
            AMA: AM584(fabG)
            AMF: AMF_436(fabG)
            ACN: ACIS_00728(fabG)
            APH: APH_0668(fabG)
            ERU: Erum3840(fabG)
            ERW: ERWE_CDS_03960(fabG)
            ERG: ERGA_CDS_03920(fabG)
            ECN: Ecaj_0374
            ECH: ECH_0669(fabG)
            NSE: NSE_0665(fabG)
            NRI: NRI_0642
            PUB: SAR11_0707(fabG) SAR11_0767
            MLO: mll1017(fabG) mll1981 mll5243 mll6717(fabG) mlr0808 mlr1583
                 mlr2780 mlr6518(fabG) mlr6807 mlr7850(fabG)
            MCI: Mesci_0269 Mesci_0299 Mesci_0645 Mesci_2032 Mesci_2095
                 Mesci_2838 Mesci_4112 Mesci_4406 Mesci_4751 Mesci_5395
            MES: Meso_0411 Meso_1537 Meso_1768 Meso_3774 Meso_4522
            PLA: Plav_0130 Plav_0158 Plav_0371 Plav_0483 Plav_1501 Plav_1519
                 Plav_2616 Plav_3359
            SME: SM_b20493 SMa0854(nodG) SMa0959(fabG) SMc00572(fabG) SMc01157
            SMD: Smed_0745 Smed_2901 Smed_3033 Smed_3570 Smed_6193
            RHI: NGR_b04340(fabG1) NGR_b10630 NGR_b13130 NGR_c08910 NGR_c30920
            ATU: Atu0990 Atu1095(fabG) Atu3531(fabG) Atu3813(fabG) Atu4595
                 Atu4877 Atu5122(fabG) Atu5250(fabG)
            ARA: Arad_14029 Arad_1515 Arad_1668(fabG) Arad_1834 Arad_3575
                 Arad_4291 Arad_4914 Arad_7211 Arad_7307 Arad_7507 Arad_7509
                 Arad_9222 Arad_9489
            AVI: Avi_1391 Avi_1528(fabG) Avi_2420 Avi_5308 Avi_5877 Avi_5878
                 Avi_9206(fabG)
            RET: RHE_CH01047(ypch00346) RHE_CH01307(ypch00443)
                 RHE_CH01443(fabG2) RHE_CH03352(ypch01170) RHE_PE00207(ype00103)
                 RHE_PF00144(ypf00064)
            REC: RHECIAT_CH0001175 RHECIAT_CH0001403 RHECIAT_CH0001511(fabG2)
                 RHECIAT_CH0003226 RHECIAT_CH0003597 RHECIAT_CH0004143
                 RHECIAT_PA0000160
            RLE: RL1193 RL1456 RL1558(fabG) RL2674(fabG) RL3779 RL3854 RL4027
                 pRL110303 pRL120119 pRL120143 pRL120144 pRL80048 pRL90210
            RLT: Rleg2_0719 Rleg2_0941 Rleg2_1057 Rleg2_3099 Rleg2_3641
                 Rleg2_5878 Rleg2_6280
            RLG: Rleg_0806 Rleg_1090 Rleg_1200 Rleg_2210 Rleg_3357 Rleg_3437
                 Rleg_3555 Rleg_3930 Rleg_5680 Rleg_6173 Rleg_6786
            LAS: CLIBASIA_02110
            LSO: CKC_05600
            BME: BMEI0032 BMEI1477(fabG) BMEII0063 BMEII0283(fabG)
                 BMEII0514(fabG) BMEII0872(fabG)
            BMI: BMEA_A0493(fabG) BMEA_A2100 BMEA_B0032 BMEA_B0375(fabG)
                 BMEA_B0755(fabG) BMEA_B0998(fabG)
            BMF: BAB1_0483(fabG) BAB1_2039 BAB2_0029 BAB2_0461(fabG)
                 BAB2_0826(fabG) BAB2_0975(fabG)
            BMB: BruAb1_0480(fabG) BruAb1_2014 BruAb2_0030 BruAb2_0455(fabG)
                 BruAb2_0805(fabG) BruAb2_0953(fabG)
            BMC: BAbS19_I04470(fabG) BAbS19_I19100 BAbS19_II00280
                 BAbS19_II04360(fabG) BAbS19_II07650(fabG) BAbS19_II09040(fabG)
            BMS: BR0458(fabG) BR2039 BRA0030 BRA0396(fabG) BRA0777(fabG)
                 BRA1013(fabG)
            BMT: BSUIS_A0484(fabG) BSUIS_A1881(gdhII) BSUIS_B0032
                 BSUIS_B0399(fabG) BSUIS_B0769(fabG) BSUIS_B1008(fabG)
            BOV: BOV_0463(fabG) BOV_A0339(fabG) BOV_A0727(fabG) BOV_A0955(fabG)
            BCS: BCAN_A0463(fabG) BCAN_A2086(gdhII) BCAN_B0032(fabG)
                 BCAN_B0399(fabG) BCAN_B0789(fabG) BCAN_B1033(fabG)
            BMR: BMI_I2061 BMI_I460(fabG) BMI_II1006(fabG) BMI_II30
                 BMI_II393(fabG) BMI_II770(fabG)
            OAN: Oant_0571(fabG) Oant_0879 Oant_1287(fabG) Oant_2101 Oant_3448
                 Oant_3955(fabG)
            BJA: bll1230 bll2747(fabG) bll3028 bll3913(fabG) bll4020 bll6359
                 bll7782 bll7880 bll7886 blr1495 blr1893(fabG) blr4083(fabG)
                 blr5634 blr6288 blr7888
            BRA: BRADO1083 BRADO1085 BRADO1160 BRADO2099 BRADO3101
                 BRADO3311(fabG) BRADO4807 BRADO6290 BRADO6422 BRADO6424
            BBT: BBta_1210 BBta_1212 BBta_3549 BBta_3818(fabG) BBta_4242
                 BBta_6963 BBta_6964 BBta_7764(fabG)
            RPA: RPA0895 RPA0896 RPA1683 RPA1684 RPA2160 RPA2417 RPA3074(fabG2)
                 RPA3304(fabG3) RPA3474(fabG4) RPA4596(fabG5) RPA4657(kduD)
            RPB: RPB_0994 RPB_2093 RPB_2467 RPB_3242 RPB_3848 RPB_3849 RPB_3897
                 RPB_4075 RPB_4527 RPB_4528
            RPC: RPC_2300 RPC_3013 RPC_3184 RPC_3650 RPC_3795
            RPD: RPD_1097 RPD_1500 RPD_2979 RPD_3326 RPD_3811 RPD_4287 RPD_4365
            RPE: RPE_0118 RPE_2271 RPE_3306 RPE_3690 RPE_3918
            RPT: Rpal_0963 Rpal_0964 Rpal_1879 Rpal_2453 Rpal_3484 Rpal_3725
                 Rpal_3838 Rpal_3964 Rpal_5077 Rpal_5138
            RPX: Rpdx1_1056 Rpdx1_1057 Rpdx1_1900 Rpdx1_2134 Rpdx1_2353
                 Rpdx1_3366 Rpdx1_3839
            NWI: Nwi_1688
            NHA: Nham_2100(fabG) Nham_2353
            OCA: OCAR_6369(fabG) OCAR_7097
            BHE: BH05350(fabG)
            BQU: BQ04530(fabG)
            BBK: BARBAKC583_0497(fabG)
            BTR: Btr_0817(fabG)
            BGR: Bgr_06180(fabG)
            BCD: BARCL_0550(fabG)
            XAU: Xaut_1016 Xaut_1358(fabG) Xaut_1622(fabG) Xaut_1623 Xaut_1907
                 Xaut_3115 Xaut_4068
            AZC: AZC_0732 AZC_1315 AZC_2061 AZC_2269 AZC_2650 AZC_3348 AZC_4313
                 AZC_4379
            SNO: Snov_1085 Snov_1730 Snov_4066 Snov_4089 Snov_4265 Snov_4267
            MEX: Mext_0292 Mext_0557 Mext_0755 Mext_4592
            MEA: Mex_1p0182 Mex_1p0377(fabG) Mex_1p5043
            MDI: METDI0165 METDI0528(fabG) METDI5644
            MRD: Mrad2831_0334(fabG) Mrad2831_1722 Mrad2831_1897 Mrad2831_1938
                 Mrad2831_2853(fabG) Mrad2831_5771
            MET: M446_1438(fabG) M446_3175 M446_3199 M446_4913 M446_5987
                 M446_6526
            MPO: Mpop_0368 Mpop_0528 Mpop_1252(fabG)
            MCH: Mchl_0336 Mchl_0492 Mchl_5053
            MNO: Mnod_0228 Mnod_1050(fabG) Mnod_2255 Mnod_2786 Mnod_2895
                 Mnod_3070 Mnod_3482 Mnod_3752(fabG) Mnod_6725 Mnod_7299
                 Mnod_8559
            BID: Bind_2299 Bind_2891
            MSL: Msil_0061 Msil_0895 Msil_3776
            HDN: Hden_0561 Hden_1711 Hden_2730
            RVA: Rvan_0041 Rvan_0936 Rvan_2624
            CCR: CC_1675 CC_2836
            CCS: CCNA_01747 CCNA_01880 CCNA_02927
            CAK: Caul_0440 Caul_0577 Caul_0993 Caul_1370 Caul_1887 Caul_1891
                 Caul_2518
            CSE: Cseg_0525 Cseg_0778 Cseg_1772 Cseg_2303 Cseg_2438 Cseg_2744
                 Cseg_3217
            PZU: PHZ_c1118 PHZ_c1119 PHZ_c1558(fabG) PHZ_c2229
            BSB: Bresu_2029 Bresu_2595 Bresu_2871 Bresu_2894
            AEX: Astex_1931 Astex_2137 Astex_2142 Astex_2788
            SIL: SPO0128(fabG) SPO2275(fabG) SPO2413 SPO2692
            SIT: TM1040_1051 TM1040_1803
            RSP: RSP_0610 RSP_2371 RSP_2461(fabG) RSP_2538(fabG) RSP_3062(fabG)
                 RSP_3440 RSP_3888(fabG)
            RSH: Rsph17029_1124 Rsph17029_1197 Rsph17029_3085 Rsph17029_3790
                 Rsph17029_4152
            RSQ: Rsph17025_1069 Rsph17025_1985 Rsph17025_2057 Rsph17025_3894
            RSK: RSKD131_0682 RSKD131_0777 RSKD131_0851 RSKD131_3200
                 RSKD131_3237 RSKD131_3606 RSKD131_4467
            RCP: RCAP_rcc01676(fabG)
            JAN: Jann_0774(fabG) Jann_1207 Jann_1626
            RDE: RD1_0098(fabG) RD1_3039 RD1_3261 RD1_3872
            PDE: Pden_1769 Pden_2349 Pden_3419
            DSH: Dshi_1339 Dshi_1429(fabG) Dshi_2182 Dshi_2891(fabG)
            KVU: EIO_1141 EIO_2624
            MMR: Mmar10_1215
            HNE: HNE_0974 HNE_2158(fabG)
            HBA: Hbal_1301 Hbal_1939 Hbal_2758 Hbal_2769
            ZMO: ZMO1222 ZMO1946
            ZMN: Za10_0111
            NAR: Saro_1428 Saro_2510 Saro_3763 Saro_3807
            SAL: Sala_1896
            SWI: Swit_0087 Swit_0740 Swit_1426 Swit_1570 Swit_1607 Swit_1658
                 Swit_1666 Swit_1669 Swit_1854 Swit_3634
            SJP: SJA_C1-16060(fabG) SJA_C1-18780 SJA_C1-26960 SJA_C1-26970
                 SJA_C2-03730
            ELI: ELI_07335
            GOX: GOX1399(fabG) GOX2040
            GBE: GbCGDNIH1_0057(fabG) GbCGDNIH1_1049 GbCGDNIH1_2211
            ACR: Acry_1259(fabG) Acry_1526 Acry_1641 Acry_1734 Acry_1855
                 Acry_1860 Acry_2467
            GDI: GDI_0231 GDI_2664 GDI_2672 GDI_2730 GDI_2943(fabG)
                 GDI_3003(fabG)
            GDJ: Gdia_0877 Gdia_0886 Gdia_2299 Gdia_3406
            APT: APA01_11750 APA01_22030
            RRU: Rru_A0416 Rru_A3017(fabG)
            RCE: RC1_1571(fabG)
            MAG: amb2106 amb2842
            AZL: AZL_013150(fabG) AZL_016740(fabG) AZL_a06540(fabG)
                 AZL_a08840(fabG) AZL_b02080(fabG) AZL_d02380(fabG) AZL_d04540
            PBR: PB2503_11249
            APB: SAR116_0623 SAR116_0640 SAR116_0921 SAR116_0926
            MGM: Mmc1_1874
            DIN: Selin_0492 Selin_0580
            BSU: BSU15910(fabG) BSU16870(fabG) BSU29420(fabG)
            BSS: BSUW23_08185(fabG) BSUW23_08680(ymfI) BSUW23_09850(yoxD)
                 BSUW23_14250(ytkK) BSUW23_16100 BSUW23_16455(yvaG)
                 BSUW23_18610(ywfH)
            BHA: BH0506(fabG) BH0932 BH1842 BH2391 BH2491(fabG) BH3182(fabG)
                 BH3896
            BAN: BA_1958(fabG) BA_3385(fabG) BA_3440 BA_3610(fabG) BA_3921(fabG)
                 BA_3989(fabG) BA_4874(fabG)
            BAR: GBAA_1958(fabG) GBAA_3385(fabG) GBAA_3440 GBAA_3610(fabG)
                 GBAA_3921(fabG) GBAA_3989(fabG) GBAA_4874(fabG)
            BAT: BAS0174(fabG) BAS1819(fabG) BAS3138(fabG) BAS3188 BAS3349(fabG)
                 BAS3635(fabG) BAS3702(fabG) BAS4522(fabG)
            BAH: BAMEG_0204 BAMEG_0642(fabG) BAMEG_0709(fabG) BAMEG_1020(fabG)
                 BAMEG_1188 BAMEG_1241 BAMEG_2632(fabG) BAMEG_4906(fabG)
            BAI: BAA_2028(fabG) BAA_3419 BAA_3473 BAA_3639(fabG) BAA_3947(fabG)
                 BAA_4013(fabG) BAA_4885(fabG)
            BAL: BACI_c02100(fabG1) BACI_c19340(fabG3) BACI_c32820 BACI_c33420
                 BACI_c34990 BACI_c37360 BACI_c38040(fabG4) BACI_c46210(fabG5)
            BCE: BC0195(fabG) BC1062 BC1958(fabG) BC3327(fabG) BC3382
                 BC3556(fabG) BC3785(fabG) BC3849(fabG) BC4624(fabG)
            BCA: BCE_0194(fabG) BCE_2044(fabG) BCE_3355(fabG) BCE_3570(fabG)
                 BCE_3820(fabG) BCE_3893(fabG) BCE_4759(fabG)
            BCZ: BCZK0164(fabG) BCZK1775(fabG) BCZK3032(fabG) BCZK3090
                 BCZK3264(fabG) BCZK3545(fabG) BCZK3610(fabG) BCZK4369(fabG)
            BCR: BCAH187_A0216 BCAH187_A2065(fabG) BCAH187_A3363 BCAH187_A3420
                 BCAH187_A3580(fabG) BCAH187_A3833(fabG) BCAH187_A3899(fabG)
                 BCAH187_A4753(fabG)
            BCB: BCB4264_A0196 BCB4264_A1097 BCB4264_A1964(fabG) BCB4264_A3339
                 BCB4264_A3663(fabG) BCB4264_A3884(fabG) BCB4264_A3950(fabG)
                 BCB4264_A4732(fabG)
            BCU: BCAH820_0193 BCAH820_1995(fabG) BCAH820_3360 BCAH820_3407
                 BCAH820_3563(fabG) BCAH820_3798(fabG) BCAH820_3865(fabG)
                 BCAH820_4742(fabG)
            BCG: BCG9842_B0503(fabG) BCG9842_B1293(fabG) BCG9842_B1415(fabG)
                 BCG9842_B1654(fabG) BCG9842_B1891 BCG9842_B2870
                 BCG9842_B3364(fabG) BCG9842_B4208 BCG9842_B5129
            BCQ: BCQ_0195(fabG) BCQ_1949(fabG) BCQ_3139 BCQ_3193 BCQ_3349(fabG)
                 BCQ_3572(fabG) BCQ_3636(fabG) BCQ_4432(fabG)
            BCX: BCA_0214 BCA_2023(fabG) BCA_3419 BCA_3649(fabG) BCA_3882(fabG)
                 BCA_3951(fabG) BCA_4740(fabG)
            BCY: Bcer98_1494(fabG) Bcer98_1545 Bcer98_2437(fabG)
                 Bcer98_2503(fabG) Bcer98_3300(fabG)
            BTK: BT9727_0164(fabG) BT9727_1793(fabG) BT9727_3125(fabG)
                 BT9727_3169 BT9727_3314(fabG) BT9727_3527(fabG)
                 BT9727_3592(fabG) BT9727_4358(fabG)
            BTL: BALH_0171 BALH_1735(fabG) BALH_3007 BALH_3196(fabG)
                 BALH_3413(fabG) BALH_3482(fabG) BALH_4205(fabG)
            BTB: BMB171_C0158 BMB171_C1745(fabG) BMB171_C3013 BMB171_C3069
                 BMB171_C3230(fabG) BMB171_C3454(fabG) BMB171_C3516(fabG)
                 BMB171_C4264(fabG)
            BWE: BcerKBAB4_0158 BcerKBAB4_1826(fabG) BcerKBAB4_3061
                 BcerKBAB4_3258(fabG) BcerKBAB4_3556(fabG) BcerKBAB4_3674(fabG)
                 BcerKBAB4_4454(fabG) BcerKBAB4_5564
            BLI: BL00414(fabG) BL01199(fabG) BL01678(yusR) BL01969(fabG)
                 BL02315(fabG) BL02426 BL03119(yvaG) BL03573
            BLD: BLi00319 BLi01605 BLi01812(fabG) BLi01911(fabG) BLi02171(fabG)
                 BLi02819 BLi02826(yvaG) BLi03081(fabG)
            BAY: RBAM_015740(fabG) RBAM_016720(fabG) RBAM_018710(fabG)
                 RBAM_022040(dfnC) RBAM_026350(fabG) RBAM_030000(yusR)
                 RBAM_030870(yvaG) RBAM_034870(ywfH)
            BAO: BAMF_1663(fabG1) BAMF_1760(ymfI) BAMF_1956(yoxD)
                 BAMF_2734(ytkK) BAMF_3213(yvaG) BAMF_3601(ywfH)
            BAE: BATR1942_05750 BATR1942_06240(fabG) BATR1942_08135(fabG)
                 BATR1942_12440(fabG) BATR1942_17625
            BCL: ABC0346 ABC0368 ABC1310 ABC2206 ABC2301(fabG) ABC2734(fabG)
                 ABC3532 ABC3620 ABC3762(fabG)
            BPU: BPUM_1285 BPUM_1490(fabG1) BPUM_1592(fabG) BPUM_2574(fabG)
                 BPUM_2971 BPUM_3425(ywfH)
            BPF: BpOF4_00355(fabG) BpOF4_02390 BpOF4_03465(fabG) BpOF4_10840
                 BpOF4_12445 BpOF4_16105 BpOF4_19620
            BMQ: BMQ_0638(fabG) BMQ_1269 BMQ_1310 BMQ_1669 BMQ_2020 BMQ_2717
                 BMQ_3461(fabG) BMQ_4125(fabG) BMQ_4221(fabG)
            BMD: BMD_0641(fabG) BMD_1253 BMD_1290 BMD_1639 BMD_1976 BMD_2704
                 BMD_3454(fabG) BMD_3714 BMD_4112(fabG) BMD_4208(fabG)
            BSE: Bsel_1337 Bsel_1710 Bsel_1805 Bsel_2617 Bsel_2736 Bsel_2808
                 Bsel_2817
            BCO: Bcell_0663 Bcell_0944 Bcell_0969 Bcell_2310 Bcell_2436
                 Bcell_2535 Bcell_3239
            OIH: OB0671 OB1524(fabG) OB1618 OB2792 OB3475(fabG)
            GKA: GK1026 GK1190(fabG) GK1289(fabG) GK1471 GK1655 GK2753(fabG)
                 GK2778
            GTN: GTNG_0292 GTNG_0888 GTNG_1043(fabG) GTNG_1143(fabG) GTNG_1504
                 GTNG_2035 GTNG_2678(fabG)
            GWC: GWCH70_0923 GWCH70_1081(fabG) GWCH70_1182(fabG) GWCH70_1779
                 GWCH70_2699(fabG)
            GYM: GYMC10_0253 GYMC10_1406(fabG) GYMC10_2883 GYMC10_3687
                 GYMC10_3804 GYMC10_4116 GYMC10_4244 GYMC10_5462(fabG)
            GYC: GYMC61_0738 GYMC61_0764(fabG) GYMC61_1799 GYMC61_1972(fabG)
                 GYMC61_2074(fabG) GYMC61_2203 GYMC61_2495
            GYA: GYMC52_0926 GYMC52_1095 GYMC52_1198 GYMC52_1331 GYMC52_1623
                 GYMC52_2788 GYMC52_2814
            GCT: GC56T3_0714 GC56T3_0740 GC56T3_1856 GC56T3_2264 GC56T3_2363
                 GC56T3_2546
            GMC: GY4MC1_0816 GY4MC1_1790 GY4MC1_2617 GY4MC1_2719 GY4MC1_2872
            AFL: Aflv_0486(fabG) Aflv_1265 Aflv_1536(fabG) Aflv_1772(fabG)
                 Aflv_1935(fabG)
            SAU: SA1074(fabG) SA1123
            SAV: SAV1231(fabG) SAV1280
            SAW: SAHV_1221(fabG) SAHV_1270
            SAH: SaurJH1_1315 SaurJH1_1366
            SAJ: SaurJH9_1290 SaurJH9_1340
            SAM: MW1114(fabG) MW1163
            SAS: SAS1165 SAS1214
            SAR: SAR1207(fabG) SAR1256
            SAC: SACOL1245(fabG1) SACOL1299
            SAX: USA300HOU_1167(fabG) USA300HOU_1212
            SAA: SAUSA300_1124(fabG) SAUSA300_1173
            SAO: SAOUHSC_01199 SAOUHSC_01257
            SAE: NWMN_1141(fabG) NWMN_1189
            SAD: SAAV_1203(fabG1) SAAV_1255
            SAB: SAB1095(fabG)
            SEP: SE0324(fabG) SE0906 SE0957
            SER: SERP0201(fabG) SERP0797(fabG) SERP0847
            SHA: SH0230 SH1633 SH1683(fabG)
            SSP: SSP1485 SSP1530(fabG) SSP1538
            SCA: Sca_0854(fabG) Sca_0921 Sca_2279(fabG) Sca_2287
            SLG: SLGD_00216 SLGD_00219 SLGD_00349 SLGD_01614 SLGD_01675
            SSD: SPSINT_0940 SPSINT_1010
            LMO: lmo1394 lmo1807(fabG) lmo2815(fabG)
            LMF: LMOf2365_1413 LMOf2365_1835(fabG) LMOf2365_2806(fabG)
            LMH: LMHCC_0750(fabG) LMHCC_1175 LMHCC_2706(fabG)
            LMC: Lm4b_01403 Lm4b_01823(fabG) Lm4b_02788(fabG)
            LMN: LM5578_0042 LM5578_1535 LM5578_2009
            LMY: LM5923_0042 LM5923_1487 LM5923_1960
            LIN: lin1431 lin1921 lin2948(fabG)
            LWE: lwe1410 lwe1826(fabG) lwe2751(fabG)
            LSG: lse_1311 lse_1787(fabG)
            LSP: Bsph_0252 Bsph_1519(fabG) Bsph_1623 Bsph_2051(fabG) Bsph_2214
            ESI: Exig_1021 Exig_1648 Exig_1908 Exig_2222(fabG)
            EAT: EAT1b_0434 EAT1b_0681(fabG) EAT1b_1301 EAT1b_2885
            MCL: MCCL_0305 MCCL_0816(fabG) MCCL_0871
            BBE: BBR47_11710 BBR47_15800 BBR47_22080(fabG) BBR47_25270
                 BBR47_27240 BBR47_30550 BBR47_34040 BBR47_36250(fabG)
                 BBR47_56470
            PJD: Pjdr2_1692(fabG) Pjdr2_3073 Pjdr2_3386 Pjdr2_3491 Pjdr2_4638
                 Pjdr2_4855(fabG) Pjdr2_5053 Pjdr2_6074 Pjdr2_6220
            PPY: PPE_00983 PPE_01849 PPE_01953 PPE_02490 PPE_03909 PPE_04580
                 PPE_04777 PPE_04783
            PPM: PPSC2_c2051 PPSC2_c2163 PPSC2_c2569 PPSC2_c2845 PPSC2_c4390
                 PPSC2_c5085 PPSC2_c5301 PPSC2_c5306
            AAC: Aaci_0146 Aaci_0156 Aaci_1266 Aaci_1344 Aaci_2067(fabG)
                 Aaci_2186(fabG)
            BTS: Btus_0471 Btus_0756 Btus_1260 Btus_1443 Btus_1586 Btus_1870
                 Btus_1974 Btus_3057
            LLA: L0185(fabG) L1530(fabG) L27694(fabG2)
            LLK: LLKF_0794(fabG) LLKF_0814(yiaB) LLKF_1959(fabG)
            LLC: LACR_0824(fabG) LACR_0845(fabG) LACR_1474 LACR_1960
            LLM: llmg_1762(fabG) llmg_1784(fabG)
            SPY: SPy_0440(fabG) SPy_1749(fabG)
            SPZ: M5005_Spy_0359(fabG) M5005_Spy_1490(fabG)
            SPM: spyM18_0483(fabG) spyM18_1821(fabG)
            SPG: SpyM3_0309(fabG) SpyM3_1523(fabG)
            SPS: SPs0343(fabG) SPs1548(fabG)
            SPH: MGAS10270_Spy0362(fabG) MGAS10270_Spy1558(fabG)
            SPI: MGAS10750_Spy0361(fabG) MGAS10750_Spy1549(fabG)
            SPJ: MGAS2096_Spy0378(fabG) MGAS2096_Spy1518(fabG)
            SPK: MGAS9429_Spy0362(fabG) MGAS9429_Spy1492(fabG)
            SPF: SpyM50355(fabG) SpyM51506(fabG)
            SPA: M6_Spy0383(fabG) M6_Spy1484(fabG)
            SPB: M28_Spy0348(fabG) M28_Spy1479(fabG)
            SOZ: Spy49_0372(fabG) Spy49_1365c(fabG)
            SPN: SP_0421(fabG) SP_0793(fabG)
            SPD: SPD_0384(fabG) SPD_0695(fabG)
            SPR: spr0381(fabG) spr0701(fabG)
            SPW: SPCG_0419(fabG) SPCG_0742(fabG)
            SPX: SPG_0387(fabG) SPG_0723(fabG)
            SNE: SPN23F_03960(fabG) SPN23F_07200(fabG)
            SPV: SPH_0529(fabG) SPH_0895(fabG)
            SNM: SP70585_0492(fabG) SP70585_0837(fabG)
            SJJ: SPJ_0407(fabG) SPJ_0737(fabG)
            SPP: SPP_0452(fabG) SPP_0802(fabG)
            SNT: SPT_0458(fabG) SPT_1406(fabG)
            SNC: HMPREF0837_10712(fabG) HMPREF0837_11699
            SNB: SP670_0495(fabG) SP670_1531
            SNP: SPAP_0439 SPAP_0769
            SAG: SAG0348(fabG) SAG1544(fabG)
            SAN: gbs0335(fabG) gbs1600(fabG)
            SAK: SAK_0422(fabG) SAK_1566(fabG)
            SMU: SMU.1740(fabG)
            SMC: SmuNN2025_0383(fabG)
            STC: str0387(fabG)
            STL: stu0387(fabG)
            STE: STER_0433(fabG)
            SSA: SSA_1650(fabG) SSA_1936(fabG)
            SSU: SSU05_1587(fabG) SSU05_1803(fabG)
            SSV: SSU98_1597(fabG) SSU98_1807(fabG)
            SSB: SSUBM407_1477(fabG) SSUBM407_1676(fabG)
            SSI: SSU1400(fabG) SSU1603(fabG)
            SSS: SSUSC84_1430(fabG) SSUSC84_1628(fabG)